Cited by 354Substance Abuse Treatment and OutcomesNeural and Behavioral Psychology StudiesNeurotransmitter Receptor Influence on Behavior

Impulsivity in abstinent alcohol-dependent patients: relation to control subjects and type 1-/type 2 like traits

Bjork, James M., Hommer, Daniel W., Grant, Steven J., Danube, Cinnamon·2004·Alcohol

Abstract

Extensive literature has linked behavior control problems in childhood to risk for alcoholism, but impulsivity in alcohol-dependent adults has not been well characterized. Using a variety of laboratory measures of impulsivity, we assessed whether detoxified alcohol-dependent patients [(ADP); n = 130] were more impulsive than control subjects [(CS); n = 41]. In comparison with CS, ADP demonstrated (1) increased rates of commission errors, but not omission errors, in a continuous performance test, (2) a more severe devaluation of delayed reward, (3) increased rates of risky responses in a new risk-taking paradigm, and (4) higher psychometric scores of impulsivity and aggression. Across all subjects, aggressiveness correlated significantly with severity of delay discounting. A post hoc analysis of data obtained for male ADP indicated that, in comparison with patients with late onset of problem drinking and no problem-drinking parent, those ADP with earlier age of problem drinking and who reported a problem-drinking father (type 2-like alcohol dependence) demonstrated faster response latencies and more responses to non-target stimuli (commission errors) in the continuous performance test, as well as higher psychometric aggression. In contrast, these subtypes of male ADP did not differ in delay discounting and risk taking. These findings collectively indicate that, in comparison with CS, ADP are more impulsive in several dimensions, with elevated impulsivity in a working memory task as well as aggressivity characteristic of alcohol-dependent men with type 2-like features.

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Crossref · 10.1016/j.alcohol.2004.06.012

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Authors
Bjork, J. M., Hommer, D. W., Grant, S. J., & Danube, C.
Affiliations
National Institutes of Health (US)
Corresponding author
Bjork, James M.
Venue
Alcohol
Publisher
Elsevier BV
Published
2004-10
Volume
34
Issue
2-3
Pages
133-150
ISSN
0741-8329 (ISSN-L)
OpenAlex
W2072715247
Cited by
354
References
98
Citations by year
2026: 4 · 2025: 2 · 2024: 5 · 2023: 5 · 2022: 7 · 2021: 6 · 2020: 58 · 2019: 15 · 2018: 14 · 2017: 12 · 2016: 15 · 2015: 24 · 2014: 30 · 2013: 34 · 2012: 26
FWCI
4.81
Type
journal article
Language
en
Open access
closed
Locations
  • Alcohol (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institute on Alcohol Abuse and Alcoholism
  • National Institute of General Medical Sciences
Topics
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords
impulsivity, alcoholism, alcohol withdrawal, delay discounting, risk-taking, aggression, commission errors, omission errors, continuous performance test, working memory, paternal alcohol use
MeSH terms
Adolescent, Adult, Alcoholism, Female, Humans, Impulsive Behavior, Male, Middle Aged, Neuropsychological Tests, Psychomotor Performance, Reaction Time, Risk-Taking, Temperance

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