The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Direct 3D bioprinting of perfusable vascular constructs using a blend bioink
Open accessAbstract
Despite the significant technological advancement in tissue engineering, challenges still exist towards the development of complex and fully functional tissue constructs that mimic their natural counterparts. To address these challenges, bioprinting has emerged as an enabling technology to create highly organized three-dimensional (3D) vascular networks within engineered tissue constructs to promote the transport of oxygen, nutrients, and waste products, which can hardly be realized using conventional microfabrication techniques. Here, we report the development of a versatile 3D bioprinting strategy that employs biomimetic biomaterials and an advanced extrusion system to deposit perfusable vascular structures with highly ordered arrangements in a single-step process. In particular, a specially designed cell-responsive bioink consisting of gelatin methacryloyl (GelMA), sodium alginate, and 4-arm poly(ethylene glycol)-tetra-acrylate (PEGTA) was used in combination with a multilayered coaxial extrusion system to achieve direct 3D bioprinting. This blend bioink could be first ionically crosslinked by calcium ions followed by covalent photocrosslinking of GelMA and PEGTA to form stable constructs. The rheological properties of the bioink and the mechanical strengths of the resulting constructs were tuned by the introduction of PEGTA, which facilitated the precise deposition of complex multilayered 3D perfusable hollow tubes. This blend bioink also displayed favorable biological characteristics that supported the spreading and proliferation of encapsulated endothelial and stem cells in the bioprinted constructs, leading to the formation of biologically relevant, highly organized, perfusable vessels. These characteristics make this novel 3D bioprinting technique superior to conventional microfabrication or sacrificial templating approaches for fabrication of the perfusable vasculature. We envision that our advanced bioprinting technology and bioink formulation may also have significant potentials in engineering large-scale vascularized tissue constructs towards applications in organ transplantation and repair.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“In this context, the fast development of new fabrication techniques, such as 3D bioprinting, has led to a general decline in the cost and the specialized work involved in fabricating these chips [65 -67].”
From 3D In Vitro Model (R)evolution: Unveiling Tumor–Stroma Interactions (2021) · cites this paper as [65]
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“To this end, considerable efforts were made in developing hydrogel-based inks or printing techniques to enhance 3D stability and shape fidelity, such as printing multimaterial inks with combined nozzle system24, 25, photo-crosslinkable hydrogels17, 26, 27, adding viscosifiers28–30, or printing in sacrificial supporting materials31–33.”
From Fibre-infused gel scaffolds guide cardiomyocyte alignment in 3D-printed ventricles (2023) · cites this paper as [24]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
3D bioprinting of tissues and organs
Murphy, S. V., & Atala, A. (2014) · Nature Biotechnology · doi:10.1038/nbt.2958 · Cited by 7,034
Hydrogels for biomedical applications
Hoffman, A. S. (2002) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(01)00239-3 · Cited by 4,864
Hydrogels for biomedical applications
Hoffman, A. S. (2012) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2012.09.010 · Cited by 3,396
Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels
Yue, K., Trujillo-de Santiago, G., Alvarez, M. M., Tamayol, A., Annabi, N., & Khademhosseini, A. (2015) · Biomaterials · doi:10.1016/j.biomaterials.2015.08.045 · Cited by 3,146
Self-citationHydrogels in regenerative medicine
Slaughter, B. V., Khurshid, S. S., Fisher, O. Z., Khademhosseini, A., & Peppas, N. A. (2009) · Advanced Materials · doi:10.1002/adma.200802106 · Cited by 2,703
Self-citationA 3D bioprinting system to produce human-scale tissue constructs with structural integrity
Kang, H.-W., Lee, S. J., Ko, I. K., Kengla, C., Yoo, J. J., & Atala, A. (2016) · Nature Biotechnology · doi:10.1038/nbt.3413 · Cited by 2,622
Cell-laden microengineered gelatin methacrylate hydrogels
Nichol, J. W., Koshy, S. T., Bae, H., Hwang, C. M., Yamanlar, S., & Khademhosseini, A. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.03.064 · Cited by 2,377
Self-citationHyaluronic Acid Hydrogels for Biomedical Applications
Burdick, J. A., & Prestwich, G. D. (2011) · Advanced Materials · doi:10.1002/adma.201003963 · Cited by 2,150
3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs
Kolesky, D. B., Truby, R. L., Gladman, A. S., Busbee, T. A., Homan, K. A., & Lewis, J. A. (2014) · Advanced Materials · doi:10.1002/adma.201305506 · Cited by 2,102
Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues
Miller, J. S., Stevens, K. R., Yang, M. T., Baker, B. M., Nguyen, D.-H. T., Cohen, D. M., Toro, E., Chen, A. A., Galie, P. A., Yu, X., et al. (2012) · Nature Materials · doi:10.1038/nmat3357 · Cited by 1,917
Research works printed but not linked: 1
- Kolesky, 2014, 3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs, Adv. Mater., 26, 3124, 10.1002/adma.201305506 · DOI · Paper page
Cited by
Sorted by citations
Items 401–500 of 919
He, H., Li, D., Lin, Z., Peng, L., Yang, J., Wu, M., Cheng, D., Pan, H., & Ruan, C. (2020) · Biofabrication · doi:10.1088/1758-5090/ab9906 · Cited by 41
Zeng, Z., Hu, C., Liang, Q., Tang, L., Cheng, D., & Ruan, C. (2020) · Bioactive Materials · doi:10.1016/j.bioactmat.2020.10.028 · Cited by 42
Medical 3D Printing: Tools and Techniques, Today and Tomorrow
Willson, K., & Atala, A. (2022) · Annual Review of Chemical and Biomolecular Engineering · doi:10.1146/annurev-chembioeng-092220-015404 · Cited by 41
Biomedical applications of three‐dimensional bioprinted craniofacial tissue engineering
Charbe, N. B., Tambuwala, M. M., Palakurthi, S. S., Warokar, A., Hromić‐Jahjefendić, A., Bakshi, H. A., Zacconi, F. C. M., Mishra, V. K., Khadse, S. C., Aljabali, A. A. A., et al. (2022) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10333 · Cited by 42
Bioprinted vascular tissue: Assessing functions from cellular, tissue to organ levels
Jiang, H., Li, X., Chen, T., Liu, Y., Wang, Q., Wang, Z., & Jia, J. (2023) · Materials Today Bio · doi:10.1016/j.mtbio.2023.100846 · Cited by 44
Wei, Q., An, Y., Zhao, X., Li, M., & Zhang, J. (2024) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2024.131281 · Cited by 46
Esser, T. U., Roshanbinfar, K., & Engel, F. B. (2018) · Expert Opinion on Biological Therapy · doi:10.1080/14712598.2019.1561855 · Cited by 40
Acoustic Fabrication of Living Cardiomyocyte-based Hybrid Biorobots
Wang, J., Soto, F., Ma, P., Ahmed, R., Yang, H., Chen, S., Wang, J., Liu, C., Akin, D., Fu, K. X., et al. (2022) · ACS Nano · doi:10.1021/acsnano.2c01908 · Cited by 41
Agarwal, K., Srinivasan, V., Lather, V., Pandita, D., & Vasanthan, K. S. (2022) · Journal of materials research/Pratt's guide to venture capital sources · doi:10.1557/s43578-022-00524-2 · Cited by 39
3D bioprinting microgels to construct implantable vascular tissue
Wang, X., Liu, X., Liu, W., Liu, Y., Li, A., Qiu, D., Zheng, X., & Gu, Q. (2023) · Cell Proliferation · doi:10.1111/cpr.13456 · Cited by 40
Self-citation3D bioprinted liver tissue and disease models: Current advances and future perspectives
Sun, L., Wang, Y., Zhang, S., Yang, H., & Mao, Y. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213499 · Cited by 39
Hierarchical patterning via dynamic sacrificial printing of stimuli-responsive hydrogels
Wen, H., Li, J., Payne, G. F., Feng, Q., Liang, M., Chen, J., Dong, H., & Cao, X. (2020) · Biofabrication · doi:10.1088/1758-5090/ab7e74 · Cited by 39
Uysal, B., Madduma‐Bandarage, U. S. K., Jayasinghe, H. G., & Madihally, S. V. (2025) · Gels · doi:10.3390/gels11030192 · Cited by 41
Microfluidic Spun Alginate Hydrogel Microfibers and Their Application in Tissue Engineering
Sun, T., Li, X., Shi, Q., Wang, H., Huang, Q., & Fukuda, T. (2018) · Gels · doi:10.3390/gels4020038 · Cited by 38
3D Printing Applied to Tissue Engineered Vascular Grafts
Wenger, R., & Giraud, M. (2018) · Applied Sciences · doi:10.3390/app8122631 · Cited by 38
3D-printable photocurable bioink for cartilage regeneration of tonsil-derived mesenchymal stem cells
Lee, J. S., Park, H. S., Jung, H., Lee, H., Hong, H., Lee, Y. J., Suh, Y. J., Lee, O. J., Kim, S. H., & Park, C. H. (2020) · Additive manufacturing · doi:10.1016/j.addma.2020.101136 · Cited by 38
Gerdes, S., Ramesh, S., Mostafavi, A., Tamayol, A., Rivero, I. V., & Rao, P. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00598 · Cited by 39
3D and 4D additive manufacturing techniques for vascular-like structures – A review
Solis, D. M., & Czekanski, A. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00182 · Cited by 38
Advantage of Alginate Bioinks in Biofabrication for Various Tissue Engineering Applications
Datta, S. (2023) · International Journal of Polymer Science · doi:10.1155/2023/6661452 · Cited by 38
A Printable Hydrogel Loaded with Medicinal Plant Extract for Promoting Wound Healing
Wang, X., Zhang, Y., Song, A., Wang, H., Wu, Y., Chang, W., Tian, B., Xu, J., Dai, H., Ma, Q., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303017 · Cited by 39
Self-citationTissue‐Engineered Microvessels: A Review of Current Engineering Strategies and Applications
Zhao, N., Pessell, A. F., Zhu, N., & Searson, P. C. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202303419 · Cited by 40
3D Printed Polymeric Hydrogels for Nerve Regeneration
Maiti, B., & Díaz, D. D. (2018) · Polymers · doi:10.3390/polym10091041 · Cited by 37
Grand challenges in the design and manufacture of vascular self-healing
Qamar, I. P. S., Sottos, N. R., & Trask, R. S. (2020) · Multifunctional Materials · doi:10.1088/2399-7532/ab69e2 · Cited by 39
Khalighi, S., & Saadatmand, M. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2021.11.046 · Cited by 37
Methods for biomaterials printing: A short review and perspective
Shokrani, H., Shokrani, A., & Saeb, M. R. (2022) · Methods · doi:10.1016/j.ymeth.2022.07.016 · Cited by 39
Ghahri, T., Salehi, Z., Aghajanpour, S., Eslaminejad, M. B., Kalantari, N., Akrami, M., Dinarvand, R., Jang, H. L., & Esfandyari‐Manesh, M. (2022) · Biomaterials Advances · doi:10.1016/j.bioadv.2022.213254 · Cited by 36
Gelation of Uniform Interfacial Diffusant in Embedded 3D Printing
Shin, S., Brunel, L. G., Cai, B., Kilian, D., Roth, J. G., Seymour, A. J., & Heilshorn, S. C. (2023) · Advanced Functional Materials · doi:10.1002/adfm.202307435 · Cited by 37
Self-citationCurrent developments in 3D bioprinting for tissue engineering
Cornelissen, D.-J., Faulkner‐Jones, A., & Shu, W. (2017) · Current Opinion in Biomedical Engineering · doi:10.1016/j.cobme.2017.05.004 · Cited by 39
Li, H., Li, N., Zhang, H., Zhang, Y., Suo, H., Wang, L., & Xu, M. (2020) · 3D Printing and Additive Manufacturing · doi:10.1089/3dp.2019.0115 · Cited by 36
Self-citationKim, M. H., & Nam, S. Y. (2020) · Bioprinting · doi:10.1016/j.bprint.2020.e00092 · Cited by 36
Recycling of Load‐Bearing 3D Printable Double Network Granular Hydrogels
Charlet, A., Hirsch, M., Schreiber, S., & Amstad, E. (2022) · Small · doi:10.1002/smll.202107128 · Cited by 35
Wang, P., Sun, L., Li, C., Jin, B., Yang, H., Wu, B., & Mao, Y. (2023) · International Journal of Bioprinting · doi:10.18063/ijb.694 · Cited by 37
Raddatz, L., Lavrentieva, A. V., Pepelanova, I., Bahnemann, J., Geier, D., Becker, T. M., Scheper, T. H., & Beutel, S. (2018) · Journal of Functional Biomaterials · doi:10.3390/jfb9040063 · Cited by 35
Importance of Alginate Bioink for 3D Bioprinting in Tissue Engineering and Regenerative Medicine
Datta, S., Barua, D. R., & Das, J. (2019) · IntechOpen eBooks · doi:10.5772/intechopen.90426 · Cited by 34
Microfluidic-assisted bioprinting of tissues and organoids at high cell concentrations
Serex, L., Sharma, K., Rizov, V., Bertsch, A., McKinney, J. D., & Renaud, P. (2020) · Biofabrication · doi:10.1088/1758-5090/abca80 · Cited by 38
3D Bioprinting of Nature-Inspired Hydrogel Inks Based on Synthetic Polymers
Kumar, S., Tharayil, A., & Thomas, S. (2021) · ACS Applied Polymer Materials · doi:10.1021/acsapm.1c00567 · Cited by 36
Multimaterial bioprinting approaches and their implementations for vascular and vascularized tissues
Dikyol, C., Altunbek, M., Bártolo, P., & Koç, B. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00159 · Cited by 40
Wang, Y., Kankala, R. K., Cai, Y., Tang, H., Zhu, K., Zhang, J.-T., Yang, D., Wang, S., Zhang, Y. S., & Chen, A. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121072 · Cited by 35
Self-citationGlobal hotspots and emerging trends in 3D bioprinting research
Ding, Z., Tang, N., Huang, J., Cao, X., & Wu, S. (2023) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2023.1169893 · Cited by 37
3D bioprinting in tissue engineering and regenerative medicine
Gupta, S., & Bit, A. (2021) · Cell and Tissue Banking · doi:10.1007/s10561-021-09936-6 · Cited by 34
Engineering a Chemically Defined Hydrogel Bioink for Direct Bioprinting of Microvasculature
Barrs, R. W., Jia, J., Ward, M., Richards, D., Yao, H., Yost, M. J., & Mei, Y. (2020) · Biomacromolecules · doi:10.1021/acs.biomac.0c00947 · Cited by 36
Engineering Three-Dimensional Vascularized Cardiac Tissues
Williams, M. A. C., Mair, D. B., Lee, W., Lee, E., & Kim, D. (2021) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2020.0343 · Cited by 36
Engineering Human Cardiac Muscle Patch Constructs for Prevention of Post-infarction LV Remodeling
Wang, L., Serpooshan, V., & Zhang, J. J. (2021) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2021.621781 · Cited by 35
Advances in Photocrosslinkable Materials for 3D Bioprinting
Zhang, W., Ye, W., & Yan, Y. (2021) · Advanced Engineering Materials · doi:10.1002/adem.202100663 · Cited by 34
Biomimetic Approaches in Scaffold-Based Blood Vessel Tissue Engineering
Rosellini, E., Giordano, C., Guidi, L., & Cascone, M. G. (2024) · Biomimetics · doi:10.3390/biomimetics9070377 · Cited by 33
Microphysiological Systems as Organ-Specific In Vitro Vascular Models for Disease Modeling
Nam, U., Lee, S., Ahmad, A., Yi, H., & Jeon, J. S. (2024) · BioChip Journal · doi:10.1007/s13206-024-00152-4 · Cited by 35
Engineered circulatory scaffolds for building cardiac tissue
Huang, S., Yang, Y., Yang, Q., Zhao, Q., & Ye, X. (2018) · Journal of Thoracic Disease · doi:10.21037/jtd.2017.12.92 · Cited by 32
Design Approaches for Generating Organ Constructs
Xia, Y. F., & Belmonte, J. C. I. (2019) · Cell stem cell · doi:10.1016/j.stem.2019.05.016 · Cited by 32
Hierarchical biomaterials via photopatterning-enhanced direct ink writing
Guzzi, E. A., Bischof, R., Dranseike, D., Deshmukh, D., Wahlsten, A., Bovone, G., Bernhard, S., & Tibbitt, M. W. (2021) · Biofabrication · doi:10.1088/1758-5090/ac212f · Cited by 32
3D bioprinting technology to mimic the tumor microenvironment: tumor-on-a-chip concept
Samadian, H., Jafari, S., Sepand, M. R., Alaei, L., Malvajerd, S. S., Jaymand, M., Ghobadinezhad, F., Jahanshahi, F., Hamblin, M. R., Derakhshankhah, H., et al. (2021) · Materials Today Advances · doi:10.1016/j.mtadv.2021.100160 · Cited by 33
Khanna, A., Ayan, B., Undieh, A. A., Yang, Y., & Huang, N. F. (2022) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2022.04.017 · Cited by 38
Lee, J. E., Heo, S. W., Kim, C. H., Park, S. J., Park, S.-H., & Kim, T. H. (2023) · Biomaterials Advances · doi:10.1016/j.bioadv.2023.213322 · Cited by 32
Advances and challenges of the cell-based therapies among diabetic patients
Raoufinia, R., Rahimi, H. R., Saburi, E., & Moghbeli, M. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05226-3 · Cited by 29
Fang, W., Yu, Z., Gao, G., Yang, M., Du, X., Wang, Y., & Fu, Q. (2024) · Materials Today Bio · doi:10.1016/j.mtbio.2024.101135 · Cited by 31
Biocompatible composite hydrogel with on-demand swelling-shrinking properties for 4D bioprinting
Jensen, P. J., Graham, J. P., Busch, T. K., Fitz, O. R., Jayanadh, S., Pashuck, E. T., & Gonzalez‐Fernandez, T. (2025) · Biomaterials Science · doi:10.1039/d5bm00551e · Cited by 38
Alginate Application for Heart and Cardiovascular Diseases
Xu, Z., & Lam, M. T. (2017) · Springer series in biomaterials science and engineering · doi:10.1007/978-981-10-6910-9_7 · Cited by 31
Bioprinting of Human Musculoskeletal Interface
Luo, W., Liu, H., Wang, C., Qin, Y., Liu, Q., & Wang, J. (2019) · Advanced Engineering Materials · doi:10.1002/adem.201900019 · Cited by 30
Interfacing cells with microengineered scaffolds for neural tissue reconstruction
Accardo, A., Cirillo, C., Lionnet, S., Christophe Vieu, A., & Loubinoux, I. (2019) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2019.07.020 · Cited by 31
Recent Advancements in 3D Printing and Bioprinting Methods for Cardiovascular Tissue Engineering
Kozaniti, F. K., Metsiou, D. N., Manara, A. E., Athanassiou, G., & Deligianni, D. D. (2021) · Bioengineering · doi:10.3390/bioengineering8100133 · Cited by 31
Preparation of Chitosan/Recombinant Human Collagen-Based Photo-Responsive Bioinks for 3D Bioprinting
Yang, Y., Wang, Z., Xu, Y., Xia, J., Xu, Z., Zhu, S., & Jin, M. (2022) · Gels · doi:10.3390/gels8050314 · Cited by 31
All‐Aqueous Freeform Fabrication of Perfusable Self‐Standing Soft Compartments
Gonçalves, R. C., Vilabril, S., Neves, C. M. S. S., Freire, M. G., Coutinho, J. A. P., Oliveira, M. B., & Mano, J. F. (2022) · Advanced Materials · doi:10.1002/adma.202200352 · Cited by 31
Vascularization in Bioartificial Parenchymal Tissue: Bioink and Bioprinting Strategies
Salg, G. A., Blaeser, A., Gerhardus, J. S., Hackert, T., & Kenngott, H. G. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23158589 · Cited by 33
Alarçın, E., İzbudak, B., Yüce, E., Domingo, S., Tutar, R., Titi, K., Kocaağa, B., Güner, F. S., & Bal‐Öztürk, A. (2022) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.37450 · Cited by 31
Three-Dimensional Bioprinting in Cardiovascular Disease: Current Status and Future Directions
Sun, Z.-H., Zhao, J., Leung, E., Flandes-Iparraguirre, M., Vernon, M. J., Silberstein, J., De-Juan-Pardo, E., & Jansen, S. (2023) · Biomolecules · doi:10.3390/biom13081180 · Cited by 20
Perfusable Vessel-on-a-Chip for Antiangiogenic Drug Screening with Coaxial Bioprinting
Gu, Z., Xie, M., Lv, S., Liu, N., He, J., Li, Y., Zhu, Y., Fu, J., Lin, H. P., Xie, C., et al. (2022) · International Journal of Bioprinting · doi:10.18063/ijb.v8i4.619 · Cited by 30
Recent progress of bio‐printed PEGDA ‐based bioinks for tissue regeneration
Hamedi, E., Vahedi, N., Sigaroodi, F., Parandakh, A., Hosseinzadeh, S., Zeinali, F., & Khani, M. (2023) · Polymers for Advanced Technologies · doi:10.1002/pat.6164 · Cited by 30
Clift, C. L., Blaser, M. C., Gerrits, W., Turner, M. E., Sonawane, A. R., Pham, T., Andresen, J. L., Fenton, O. S., Grolman, J. M., Campedelli, A., et al. (2024) · Science Advances · doi:10.1126/sciadv.adj9793 · Cited by 30
Wawszczak, A., Kocki, J., & Kołodyńska, D. (2024) · Journal of Biomedical Materials Research Part B Applied Biomaterials · doi:10.1002/jbm.b.35475 · Cited by 31
3D bioprinting approaches for enhancing stem cell-based neural tissue regeneration
Bektas, C. K., Luo, J., Conley, B., Le, K.-P. N., & Lee, K. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.006 · Cited by 35
Guo, Y., Liu, Y., Zhang, Z., Zhang, X., Xu, J. K., Zhang, R., Chen, G., Zhu, L., & Zhu, M. (2025) · Advanced Materials · doi:10.1002/adma.202414877 · Cited by 33
Son, J., Li, S., & Jeong, W. (2025) · Gels · doi:10.3390/gels11080636 · Cited by 38
Lv, Z., Zhao, N. R., Wu, Z., Zhu, C., & Li, Q. (2018) · Industrial & Engineering Chemistry Research · doi:10.1021/acs.iecr.8b02233 · Cited by 30
3D Bioprinting of Adipose-Derived Stem Cells for Organ Manufacturing
Wang, X., & Liu, C. (2018) · Advances in experimental medicine and biology · doi:10.1007/978-981-13-0950-2_1 · Cited by 30
Chiu, Y., Shen, Y., Lee, A. K.-X., Lin, S.-H., Wu, Y.-C., & Chen, Y. (2019) · Polymers · doi:10.3390/polym11091394 · Cited by 30
Wenger, L., Radtke, C. P., Göpper, J., Wörner, M., & Hubbuch, J. J. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.00713 · Cited by 32
Liu, S., Huang, D., Hu, Y., Zhang, J., Chen, B., Zhang, H., Dong, X., Tong, R., Li, Y., & Zhou, W. (2020) · RSC Advances · doi:10.1039/d0ra04581k · Cited by 30
Pereira, R. F., Lourenço, B. N., Bártolo, P., & Granja, P. L. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202001176 · Cited by 30
Bioprinting Au Natural: The Biologics of Bioinks
Willson, K., Atala, A., & Yoo, J. J. (2021) · Biomolecules · doi:10.3390/biom11111593 · Cited by 31
Review on novel biomaterials and innovative 3D printing techniques in biomedical applications
Pradeep, P. V., & Paul, L. (2022) · Materials Today Proceedings · doi:10.1016/j.matpr.2022.01.072 · Cited by 32
In vitro pre-vascularization strategies for tissue engineered constructs–Bioprinting and others
Liew, A. W. L., & Zhang, Y. (2017) · International Journal of Bioprinting · doi:10.18063/ijb.2017.01.008 · Cited by 29
Self-citationHeidari, F., Saadatmand, M., & Simorgh, S. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.127041 · Cited by 31
Wang, R., Zhang, C., Li, D., & Yao, Y. (2022) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2022.1057913 · Cited by 30
Settembrini, A. M., Buongiovanni, G., Settembrini, P., Alessandrino, A., Freddi, G., Vettor, G., & Martelli, E. (2023) · Frontiers in Surgery · doi:10.3389/fsurg.2023.1090565 · Cited by 29
Capillary-like Formations of Endothelial Cells in Defined Patterns Generated by Laser Bioprinting
Koch, L., Deiwick, A., & Chichkov, B. N. (2021) · Micromachines · doi:10.3390/mi12121538 · Cited by 33
Biomimetic Vasculatures by 3D‐Printed Porous Molds
Ching, T., Vasudevan, J., Chang, S., Tan, H. Y., Ranganath, A. S., Lim, C. T., Fernandez, J. G., Ng, J. J., Toh, Y., & Hashimoto, M. (2022) · Small · doi:10.1002/smll.202203426 · Cited by 29
Yu, J., Yin, Y., Leng, Y., Zhang, J., Wang, C., Chen, Y., Li, X., Wang, X., Liu, H., Liao, Y., et al. (2023) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2023.114842 · Cited by 31
Self-citationAbdollahi, S., Boktor, J. C., & Hibino, N. (2019) · Translational research · doi:10.1016/j.trsl.2019.05.005 · Cited by 29
Pan, R. L., Martyniak, K., Karimzadeh, M., Gelikman, D. G., DeVries, J., Sutter, K., Coathup, M. J., Razavi, M., Sawh-Martinez, R. F., & Kean, T. J. (2022) · Journal of Experimental Orthopaedics · doi:10.1186/s40634-022-00518-3 · Cited by 33
Hu, M. Y., Dailamy, A., Lei, X. Y., Parekh, U., McDonald, D., Kumar, A., & Mali, P. (2018) · Advanced Healthcare Materials · doi:10.1002/adhm.201800845 · Cited by 28
Bioinspired Robust All‐Aqueous Droplet via Diffusion‐Controlled Interfacial Coacervation
Huang, X., Tian, L., Wang, Z., Zhang, J., Chan, Y. S., Cheng, S. H., & Yao, X. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202004166 · Cited by 28
Oliveira, H., Medina, C. F., Stachowicz, M., dos Santos, B. P., Chagot, L., Dusserre, N., & Fricain, J. (2021) · Bioprinting · doi:10.1016/j.bprint.2021.e00134 · Cited by 32
Al‐Kattan, A., Grojo, D., Drouet, C., Mouskeftaras, A., Delaporte, P. C., Casanova, A., Robin, J. D., Magdinier, F., Alloncle, A., Constantinescu, C. D., et al. (2021) · Nanomaterials · doi:10.3390/nano11030712 · Cited by 29
la Vega, L. D., Abelseth, L., Sharma, R., Triviño-Paredes, J., Perez, M. R., & Willerth, S. M. (2021) · Advanced NanoBiomed Research · doi:10.1002/anbr.202000077 · Cited by 28
Biofabrication of tissue engineering vascular systems
Zhang, Q., Bosch-Rué, È., Pérez, R. A., & Truskey, G. A. (2021) · APL Bioengineering · doi:10.1063/5.0039628 · Cited by 30
Biomimetic bioinks of nanofibrillar polymeric hydrogels for 3D bioprinting
Wang, Y., Li, J., Li, Y., & Yang, B. (2021) · Nano Today · doi:10.1016/j.nantod.2021.101180 · Cited by 31
Zhu, B., Wang, D., Pan, H., Gong, T., Ren, Q., Wang, Z., & Guo, Y. (2022) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2022.113017 · Cited by 28
Barua, D. R., Sarkar, A., & Datta, S. (2023) · Advances in medical education, research, and ethics (AMERE) book series · doi:10.4018/978-1-6684-7164-7.ch007 · Cited by 28
vasQchip: A Novel Microfluidic, Artificial Blood Vessel Scaffold for Vascularized 3D Tissues
Kappings, V., Grün, C., Ivannikov, D., Hebeiss, I., Kattge, S., Wendland, I., Rapp, B. E., Hettel, M., Deutschmann, O., & Schepers, U. (2018) · Advanced Materials Technologies · doi:10.1002/admt.201700246 · Cited by 28
3D Bioprinting for Oncology Applications
Liu, T., Delavaux, C., & Zhang, Y. S. (2019) · Journal of 3D Printing in Medicine · doi:10.2217/3dp-2019-0004 · Cited by 28
Self-citationEvolution of bioprinting and current applications
Mendoza-Cerezo, L., Rodríguez-Rego, J. M., Macı́as-Garcı́a, A., Marcos-Romero, A. C., & Díaz-Parralejo, A. (2023) · International Journal of Bioprinting · doi:10.18063/ijb.742 · Cited by 32
Metadata
- Authors
- Jia, W., Gungor-Ozkerim, P. S., Zhang, Y. S., Yue, K., Zhu, K., Liu, W., Pi, Q., Byambaa, B., Dokmeci, M. R., Shin, S. R., & Khademhosseini, A.
- Affiliations
- Brigham and Women's Hospital (US)
- Corresponding author
- Zhang, Yu Shrike
- Shin, Su Ryon
- Khademhosseini, Ali
- ORCID
- Venue
- Biomaterials
- Publisher
- Elsevier BV
- Published
- 2016-11
- Volume
- 106
- Pages
- 58-68
- ISSN
- 0142-9612 (ISSN-L)
- PMC
- PMC5300870
- OpenAlex
- W2502401296
- Cited by
- 922
- References
- 67
- Citations by year
- 2026: 37 · 2025: 59 · 2024: 86 · 2023: 97 · 2022: 113 · 2021: 132 · 2020: 121 · 2019: 110 · 2018: 94 · 2017: 68 · 2016: 4
- FWCI
- 44.28
- Type
- journal article
- Language
- en
- Update notices
- erratum (2025-11-01)
- Open access
- bronze
- doi.org
- Licence
- Locations
- Biomaterials (acceptedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Cancer Institute (1K99CA201603-01A1)
- National Institutes of Health (HL099073, EB02597, AR057837, HL092836)
- Natural Sciences and Engineering Research Council of Canada
- National Science Foundation (DMR0847287)
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu (B.14.2.TBT.0.06.01-219-115543)
- Office of Naval Research
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › 3D Printing in Biomedical Research
- Physical Sciences › Materials Science › Biomaterials › Hydrogels: synthesis, properties, applications
- Health Sciences › Medicine › Surgery › Tissue Engineering and Regenerative Medicine
- Keywords
- 3D bioprinting, perfusable vascular networks, gelatin methacryloyl, sodium alginate, coaxial extrusion, calcium crosslinking, photocrosslinking, endothelial cells, stem cells, vascularized tissue engineering, mechanical strength
- MeSH terms
- Blood Vessels, Cells, Cultured, Equipment Design, Humans, Ink, Organ Culture Techniques, Perfusion, Neovascularization, Physiologic, Bioreactors, Bioartificial Organs, Tissue Engineering, Endothelial Cells, Tissue Scaffolds, Batch Cell Culture Techniques, Printing, Three-Dimensional
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
