Intravascular glucose/lactate sensors prepared with nitric oxide releasing poly(lactide-co-glycolide)-based coatings for enhanced biocompatibility
Open accessAbstract
Intravenous amperometric needle-type enzymatic glucose/lactate sensors intended for continuous monitoring are prepared with a novel nitric oxide (NO) releasing layer to improve device hemocompatibility. To create an underlying NO release coating, the sensors with immobilized enzymes (either glucose oxidase or lactate oxidase) are prepared with a thin layer of poly(lactide-co-glycolide) (PLGA) loaded with lipophilic diazeniumdiolate species that slowly release NO via a proton driven reaction. An outer thin layer (ca. 30 μm) of PurSil (polyurethane/dimethylsiloxane copolymer) limits the flux of glucose and lactate to the inner layer of enzyme, to provide the desired linear amperometric response. A 30 μm coating of PLGA containing 33 wt% of the appropriate NO donor (N-diazeniumdiolated dibutylhexanediamine, DBHD/N₂O₂) can release NO at a physiologically relevant rate > 1 × 10⁻¹⁰mol min⁻¹ cm⁻² for at least 7 days without influencing the analytical performance of the glucose/lactate sensors. In vitro, the sensors exhibit relatively stable amperometric response over a one-week period with high selectivity over interferences (e.g., ascorbic acid) required for blood monitoring applications. Glucose sensors implanted in the veins of rabbits for 8h exhibit significantly enhanced hemocompatibility for the NO release sensors vs. corresponding controls (without NO release in same animals), with greatly reduced thrombus formation on their surfaces. Further, the analytical performance of the NO release glucose sensors are superior to controls placed in the veins of the same animals, with a greater accuracy in measuring blood glucose levels as evaluated using a Clarke error grid type analysis.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
NO releasing intravascular glucose, pH, and CO2 sensors using diazeniumdiolated NO donors demonstrated much improved electrochemical responses over corresponding control sensors.
“Similar to oxygen sensors, NO releasing intravascular glucose,271–275 pH,275,276 and CO2275,277 sensors using diazeniumdiolated NO donors have also been tested, demonstrating much improved electrochemical responses over the corresponding control sensors.”
From Recent advances in thromboresistant and antimicrobial polymers for biomedical applications: just say yes to nitric oxide (NO) (2016) · cites this paper as [271]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Harris, R. S., & Thiman, K. V. (1948) · The American Journal of the Medical Sciences · doi:10.1097/00000441-194801000-00035 · Cited by 792 · see citing works
Serum Lactate as a Predictor of Mortality in Emergency Department Patients with Infection
Shapiro, N. I., Howell, M. D., Talmor, D. S., Nathanson, L. A., Lisbon, A., Wolfe, R. E., & Weiss, J. W. (2005) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2004.12.006 · Cited by 750 · see citing works
Methods for reducing biosensor membrane biofouling
Wisniewski, N., & Reichert, M. (2000) · Colloids and Surfaces B: Biointerfaces · doi:10.1016/s0927-7765(99)00148-4 · Cited by 543 · see citing works
Arnold, R. C., Shapiro, N. I., Jones, A. E., Schorr, C., Pope, J., Casner, E., Parrillo, J. E., Dellinger, R. P., & Trzeciak, S. W. (2009) · Shock · doi:10.1097/shk.0b013e3181971d47 · Cited by 398 · see citing works
Frost, M. C., Reynolds, M. M., & Meyerhoff, M. E. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2004.06.006 · Cited by 343 · see citing works
Self-citationEstimation of nitric oxide production and reactionrates in tissue by use of a mathematical model
Vaughn, M. W., Kuo, L., & Liao, J. C. (1998) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.1998.274.6.h2163 · Cited by 338 · see citing works
Design and in vitro studies of a needle-type glucose sensor for subcutaneous monitoring
Bindra, D. S., Zhang, Y., Wilson, G. S., Sternberg, R., Thevenot, D. R., Moatti, D., & Reach, G. (1991) · Analytical Chemistry · doi:10.1021/ac00017a008 · Cited by 309 · see citing works
Recent Advances in the Stabilization of Proteins Encapsulated in Injectable PLGA Delivery Systems
Schwendeman, S. P. (2002) · Critical Reviews in Therapeutic Drug Carrier Systems · doi:10.1615/critrevtherdrugcarriersyst.v19.i1.20 · Cited by 235 · see citing works
Electropolymerized films to prevent interferences and electrode fouling in biosensors
Geise, R. J., Adams, J. M., Barone, N. J., & Yacynych, A. M. (1991) · Biosensors and Bioelectronics · doi:10.1016/0956-5663(91)87039-e · Cited by 169 · see citing works
Tight Blood Glucose Control With Insulin in the ICU
Vanhorebeek, I., Langouche, L., & den Berghe, G. V. (2007) · CHEST Journal · doi:10.1378/chest.06-3121 · Cited by 157 · see citing works
Implantable chemical sensors for real-time clinical monitoring: progress and challenges
Frost, M. C., & Meyerhoff, M. E. (2002) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(02)00371-x · Cited by 148 · see citing works
Self-citationTight Blood Glucose Control Is Renoprotective in Critically Ill Patients
Schetz, M., Vanhorebeek, I., Wouters, P. J., Wilmer, A. P., & den Berghe, G. V. (2008) · Journal of the American Society of Nephrology · doi:10.1681/asn.2006101091 · Cited by 146 · see citing works
In Vivo Chemical Sensors: Tackling Biocompatibility
Frost, M. C., & Meyerhoff, M. E. (2006) · Analytical Chemistry · doi:10.1021/ac069475k · Cited by 145 · see citing works
Self-citationMajor, T. C., Brant, D. O., Reynolds, M. M., Bartlett, R. H., Meyerhoff, M. E., Handa, H., & Annich, G. M. (2009) · Biomaterials · doi:10.1016/j.biomaterials.2009.12.028 · Cited by 134 · see citing works
Self-citationLactate as a marker of energy failure in critically ill patients: hypothesis.
Valenza, F., Aletti, G., Fossali, T., Chevallard, G., Sacconi, F., Irace, M., & Gattinoni, L. (2005) · Critical Care · doi:10.1186/cc3818 · Cited by 128 · see citing works
Lonergan, T., Compte, A. L., Willacy, M., Chase, J. G., Shaw, G. M., Wong, X., Lotz, T., Lin, J., & Hann, C. E. (2006) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2006.8.191 · Cited by 123 · see citing works
Batchelor, M. M., Reoma, S. L., Fleser, P. S., Nuthakki, V. K., Callahan, R. E., Shanley, C. J., Politis, J. K., Elmore, J., Merz, S. I., & Meyerhoff, M. E. (2003) · Journal of Medicinal Chemistry · doi:10.1021/jm030286t · Cited by 120 · see citing works
Self-citationFleser, P. S., Nuthakki, V. K., Malinzak, L. E., Callahan, R. E., Seymour, M. L., Reynolds, M. M., Merz, S. I., Meyerhoff, M. E., Bendick, P. J., Zelenock, G. B., et al. (2004) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2004.07.007 · Cited by 110 · see citing works
Self-citationGirardin, C. M., Huot, C., Gonthier, M., & DELVIN, E. E. (2008) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2008.09.112 · Cited by 103 · see citing works
Wu, B., Gerlitz, B., Grinnell, B. W., & Meyerhoff, M. E. (2007) · Biomaterials · doi:10.1016/j.biomaterials.2007.06.002 · Cited by 102 · see citing works
Self-citationMediation of <i>in vivo</i> glucose sensor inflammatory response via nitric oxide release
Gifford, R., Batchelor, M. M., Lee, Y., Gokulrangan, G., Meyerhoff, M. E., & Wilson, G. S. (2005) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.30359 · Cited by 96 · see citing works
Self-citationFrost, M. C., Rudich, S. M., Zhang, H., Maraschio, M., & Meyerhoff, M. E. (2002) · Analytical Chemistry · doi:10.1021/ac025944g · Cited by 93 · see citing works
Self-citationVitamins and Hormones. Advances in Research and Applications.
Li, C. H. (1956) · Journal of the American Chemical Society · doi:10.1021/ja01598a092 · Cited by 85 · see citing works
Calibration of a subcutaneous amperometric glucose sensor implanted for 7 days in diabetic patients
Choleau, C., Klein, J. C., Reach, G., Aussedat, B., Demaria-Pesce, V., Wilson, G. S., Gifford, R., & Ward, W. K. (2002) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00304-9 · Cited by 76 · see citing works
Kondepati, V. R., & Heise, H. M. (2007) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-007-1229-8 · Cited by 71 · see citing works
Nitric Oxide-Releasing Sol−Gel Particle/Polyurethane Glucose Biosensors
Shin, J. H., Marxer, S. M., & Schoenfisch, M. H. (2004) · Analytical Chemistry · doi:10.1021/ac049776z · Cited by 71 · see citing works
Shapiro, N. I., Fisher, C., Donnino, M. W., Cataldo, L., Tang, A., Trzeciak, S., Horowitz, G. L., & Wolfe, R. E. (2009) · Journal of Emergency Medicine · doi:10.1016/j.jemermed.2009.07.021 · Cited by 70 · see citing works
Skrzypchak, A. M., Lafayette, N. G., Bartlett, R. H., Zhou, Z., Frost, M. C., Meyerhoff, M. E., Reynolds, M. M., & Annich, G. M. (2007) · Perfusion · doi:10.1177/0267659107080877 · Cited by 68 · see citing works
Self-citationYang, Q., Atanasov, P., & Wilkins, E. S. (1999) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(98)00109-2 · Cited by 66 · see citing works
Wu, Y., & Meyerhoff, M. E. (2008) · Talanta · doi:10.1016/j.talanta.2007.06.022 · Cited by 65 · see citing works
Self-citationWU, Y., ROJAS, A., GRIFFITH, G., SKRZYPCHAK, A., LAFAYETTE, N., BARTLETT, R., & MEYERHOFF, M. (2007) · Sensors and Actuators B: Chemical · doi:10.1016/j.snb.2006.09.025 · Cited by 65 · cited 2× · see citing works
“Recent research in this laboratory (Fleser et al., 2004; Frost nd Meyerhoff, 2004; Frost et al., 2002, 2005; Wu et al., 2007a,c) tronics 26 (2011) 4276– 4282 4277 and elsewhere (Major et al., 2010; Oh et al., 2005; Skrzypchak et al., 2007) has shown that polymers capable of releasing 1–15 × 10−10…”
BackgroundSelf-citationCalibration of a subcutaneous amperometric glucose sensor
Choleau, C., Klein, J. C., Reach, G., Aussedat, B., Demaria-Pesce, V. H., Wilson, G. S., Gifford, R., & Ward, W. K. (2002) · Biosensors and Bioelectronics · doi:10.1016/s0956-5663(01)00306-2 · Cited by 60 · see citing works
Preparation and characterization of implantable sensors with nitric oxide release coatings
Frost, M. C., Batchelor, M. M., Lee, Y.-M., Zhang, H., Kang, Y., Oh, B. K., Wilson, G. S., Gifford, R., Rudich, S. M., & Meyerhoff, M. E. (2003) · Microchemical Journal · doi:10.1016/s0026-265x(03)00033-x · Cited by 55 · see citing works
Self-citationA needle-type enzyme-based lactate sensor for in vivo monitoring
Hu, Y., Zhang, Y., & Wilson, G. S. (1993) · Analytica Chimica Acta · doi:10.1016/0003-2670(93)85008-8 · Cited by 51 · see citing works
Wu, Y., Zhou, Z., & Meyerhoff, M. E. (2007) · Journal of Biomedical Materials Research Part A · doi:10.1002/jbm.a.31105 · Cited by 48 · see citing works
Self-citationWu, Y., Rojas-Peña, Á., Griffith, G. W., et al. (2007) · PubMed · doi:10.1016/j.snb.2006.09.02 · Cited by 46 · see citing works
Investigation into immobilisation of lactate oxidase to improve stability
Lillis, B., Grogan, C., Berney, H., & Lane, W. A. (2000) · Sensors and Actuators B Chemical · doi:10.1016/s0925-4005(00)00469-x · Cited by 39 · see citing works
Miniaturized glucose biosensor modified with a nitric oxide-releasing xerogel microarray
Oh, B. K., Robbins, M. E., Nablo, B. J., & Schoenfisch, M. H. (2005) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2005.01.010 · Cited by 36 · see citing works
Bochicchio, G. V., & Scalea, T. M. (2008) · Advances in Surgery · doi:10.1016/j.yasu.2008.03.006 · Cited by 26 · see citing works
Holloway, P. A. H., Benham, S. W., & John, A. S. (2001) · Clinica Chimica Acta · doi:10.1016/s0009-8981(01)00449-1 · Cited by 11 · see citing works
Frost, M. C., & Meyerhoff, M. E. (2004) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/s0076-6879(04)81045-0 · Cited by 9 · see citing works
Self-citationNitric Oxide: News from Stem Cells to Platelets
Atri, L. D., Malaver, E., Romaniuk, M. A., Pozner, R., Negrotto, S., & Schattner, M. A. (2009) · Current Medicinal Chemistry · doi:10.2174/092986709787315513 · Cited by 9 · see citing works
Shapiro, N. I., Howell, M. D., & Talmor, D. S. (2005) · Annals of Emergency Medicine · doi:10.1016/j.annemergmed.2005.07.022 · Cited by 1 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Wo, Y., Brisbois, E. J., Bartlett, R. H., & Meyerhoff, M. E. (2016) · Biomaterials Science · doi:10.1039/c6bm00271d · Cited by 251 · see citing works
Self-citationAnti-Biofouling Strategies for Long-Term Continuous Use of Implantable Biosensors
Xu, J., & Lee, H. (2020) · Chemosensors · doi:10.3390/chemosensors8030066 · Cited by 134 · see citing works
Polymer coatings for biomedical applications: a review
Smith, J. R., & Lamprou, D. A. (2014) · Transactions of the IMF · doi:10.1179/0020296713z.000000000157 · Cited by 123 · see citing works
Teng, X., Peng, B., Xue, M., Zhong, X., Chiu, C.-Y., Yang, S. C., Qu, Y., Ruan, L., Jiang, S. H., Dubin, S., et al. (2014) · Nature Communications · doi:10.1038/ncomms4200 · Cited by 107 · see citing works
Self-citationBrisbois, E. J., Major, T. C., Goudie, M. J., Bartlett, R. H., Meyerhoff, M. E., & Handa, H. (2016) · Acta Biomaterialia · doi:10.1016/j.actbio.2016.04.025 · Cited by 87 · see citing works
Self-citationIn Vivo Chemical Sensors: Role of Biocompatibility on Performance and Utility
Soto, R. J., Hall, J. R., Brown, M. D., Taylor, J. B., & Schoenfisch, M. H. (2016) · Analytical Chemistry · doi:10.1021/acs.analchem.6b04251 · Cited by 85 · see citing works
Cai, W., Wu, J., Xi, C., & Meyerhoff, M. E. (2012) · Biomaterials · doi:10.1016/j.biomaterials.2012.07.027 · Cited by 77 · see citing works
Self-citationFrost, M. C., & Meyerhoff, M. E. (2015) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-071114-040443 · Cited by 68 · see citing works
Self-citationFreeman, M. H., Hall, J. R., & Leopold, M. C. (2013) · Analytical Chemistry · doi:10.1021/ac3037188 · Cited by 61 · see citing works
Brisbois, E. J., Kim, M., Wang, X., Mohammed, A., Major, T. C., Wu, J., Brownstein, J., Xi, C., Handa, H., Bartlett, R. H., et al. (2016) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.6b08707 · Cited by 60 · see citing works
Self-citationNitric Oxide-Releasing Silica Nanoparticle-Doped Polyurethane Electrospun Fibers
Koh, A., Carpenter, A. W., Slomberg, D. L., & Schoenfisch, M. H. (2013) · ACS Applied Materials & Interfaces · doi:10.1021/am402044s · Cited by 49 · see citing works
Chen, L., Xia, N., Li, T., Bai, Y., & Chen, X. (2016) · Microchimica Acta · doi:10.1007/s00604-016-1903-7 · Cited by 38 · see citing works
Fabrication of nitric oxide-releasing polyurethane glucose sensor membranes
Koh, A., Riccio, D. A., Sun, B., Carpenter, A. W., Nichols, S. P., & Schoenfisch, M. H. (2011) · Biosensors and Bioelectronics · doi:10.1016/j.bios.2011.06.005 · Cited by 37 · see citing works
Konopińska, K. K., Schmidt, N. J., Hunt, A. P., Lehnert, N., Wu, J., Xi, C., & Meyerhoff, M. E. (2018) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.8b05917 · Cited by 33 · see citing works
Self-citationLong-Term Accurate Continuous Glucose Biosensors via Extended Nitric Oxide Release
Malone‐Povolny, M. J., Merricks, E. P., Wimsey, L. E., Nichols, T. C., & Schoenfisch, M. H. (2019) · ACS Sensors · doi:10.1021/acssensors.9b01779 · Cited by 31 · see citing works
Ren, H., Coughlin, M. A., Major, T. C., Aiello, S., Rojas Pena, A., Bartlett, R. H., & Meyerhoff, M. E. (2015) · Analytical Chemistry · doi:10.1021/acs.analchem.5b01590 · Cited by 30 · see citing works
Self-citationNitric oxide release for improving performance of implantable chemical sensors – A review
Cha, K. H., Wang, X., & Meyerhoff, M. E. (2017) · Applied Materials Today · doi:10.1016/j.apmt.2017.10.002 · Cited by 27 · see citing works
Self-citationSchmidt, A. R., Nguyen, N. D. T., & Leopold, M. C. (2013) · Langmuir · doi:10.1021/la400359x · Cited by 24 · see citing works
Wolf, A. K., Qin, Y., Major, T. C., & Meyerhoff, M. E. (2015) · Chinese Chemical Letters · doi:10.1016/j.cclet.2015.03.002 · Cited by 21 · see citing works
Self-citationWolf, A. K., Renehan, K., Ho, K. K. Y., Carr, B. D., Chen, C., Cornell, M. S., Ye, M., Rojas-Peña, Á., & Chen, H. (2018) · Biosensors · doi:10.3390/bios8040122 · Cited by 20 · see citing works
Remote Detection for Glucose and Lactate Based on Flexible Sensor Array
Chou, J.-C., Yan, S.-J., Liao, Y.-H., Lai, C.-H., Wu, Y.-X., & Wu, C.-Y. (2018) · IEEE Sensors Journal · doi:10.1109/jsen.2018.2805292 · Cited by 19 · see citing works
Nitric oxide-releasing polyurethanes
Pant, J., Goudie, M. J., Brisbois, E. J., & Handa, H. (2016) · Elsevier eBooks · doi:10.1016/b978-0-08-100614-6.00014-7 · Cited by 18 · see citing works
Chou, J.-C., Yan, S.-J., Liao, Y.-H., Lai, C.-H., Wu, Y.-X., Wu, C.-Y., Chen, H.-Y., Huang, H.-Y., & Wu, T.-Y. (2017) · Sensors · doi:10.3390/s17071618 · Cited by 18 · see citing works
Biodegradable polymers: emerging excipients for the pharmaceutical and medical device industries
Patel, B. B., & Chakraborty, S. (2016) · International Journal of Pharmaceutical Excipients · doi:10.66617/001c.1010 · Cited by 18 · see citing works
Cha, K. H., & Meyerhoff, M. E. (2017) · ACS Sensors · doi:10.1021/acssensors.7b00430 · Cited by 16 · see citing works
Self-citationCombination of Nitric Oxide Release and Surface Texture for Mitigating the Foreign Body Response
Malone‐Povolny, M. J., Bradshaw, T. M., Merricks, E. P., Long, C. T., Nichols, T. C., & Schoenfisch, M. H. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00022 · Cited by 16 · see citing works
Zhang, Q., & Meyerhoff, M. E. (2021) · Electroanalysis · doi:10.1002/elan.202100174 · Cited by 11 · see citing works
Self-citationZhang, Q., Murray, G. P., Hill, J. E., Harvey, S. L., Rojas-Peña, Á., Choi, J. D., Zhou, Y., Bartlett, R. H., & Meyerhoff, M. E. (2020) · Analytical Chemistry · doi:10.1021/acs.analchem.0c02979 · Cited by 11 · see citing works
Self-citationHo, K. K. Y., Peng, Y.-W., Ye, M., Tchouta, L., Schneider, B., Hayes, M., Toomasian, J. M., Cornell, M. S., Rojas-Peña, Á., Charpie, J. R., et al. (2020) · Chemosensors · doi:10.3390/chemosensors8030056 · Cited by 10 · see citing works
White, C. J., Schwartz, J. M., Lehnert, N., & Meyerhoff, M. E. (2023) · Bioelectrochemistry · doi:10.1016/j.bioelechem.2023.108448 · Cited by 8 · see citing works
Self-citationJeakle, M. M. P., Major, T. C., Meyerhoff, M. E., & Bartlett, R. H. (2019) · ACS Applied Bio Materials · doi:10.1021/acsabm.9b00924 · Cited by 8 · see citing works
Self-citationZhang, Q., Stachelek, S. J., Inamdar, V. V., Alferiev, I. S., Nagaswami, C., Weisel, J. W., Hwang, J.-H., & Meyerhoff, M. E. (2020) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2020.111060 · Cited by 8 · see citing works
Self-citationImproving the in vivo stability and sensor lifetime with new blend membranes on CGM sensors
Zuo, Y., Lei, L., Huang, K., Hao, Q., Zhao, C., & Liu, H. (2024) · RSC Applied Polymers · doi:10.1039/d4lp00123k · Cited by 7 · see citing works
Implantable Biosensors for Personalized Healthcare
Mahato, K. (2024) · Springer eBooks · doi:10.1007/978-981-97-5473-1_14 · Cited by 7 · see citing works
Polymeric Materials in Coatings for Biomedical Applications
Fasiku, V. O., Fasiku, V. O., Owonubi, S. J., Mukwevho, E., Aderibigbe, B. A., Sadiku, E. R., Lemmer, Y., Ibrahim, I. D., Mochane, J., Daramola, O. O., et al. (2018) · doi:10.1002/9781119407652.ch14 · Cited by 4 · see citing works
Biodegradable polymer: An emerging excipient in pharmaceutical and medical device industry
Patel, B. B., & Chakraborty, S. (2013) · Cited by 3 · see citing works
Improving the Performance of Implantable Sensors with Nitric Oxide Release
Frost, M. C. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809275-0.00008-9 · Cited by 3 · see citing works
Improving the hemocompatibility of catheters via NO release/generation
Wo, Y., Brisbois, E. J., Bartlett, R. H., & Meyerhoff, M. E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-08-100497-5.00013-6 · Cited by 2 · see citing works
Self-citationBiomimetic Catalysts of Graphene Conjugates and Palladium Nanoparticles
Teng, X. (2014) · eScholarship (California Digital Library)
Intravascular multi-layered glucose sensors for an artificial pancreas
Saber, D., Fadhil, N., Patra, P., & Faezipour, M. (2013) · IEEE Long Island Systems, Applications and Technology Conference (LISAT) · doi:10.1109/lisat.2013.6578251
Printed Electronics Applications: Sensors, Actuators and Biosensors
(2022) · Royal Society of Chemistry eBooks · doi:10.1039/9781788019699-00516
- Authors
- Yan, Q., Major, T. C., Bartlett, R. H., & Meyerhoff, M. E.
- Affiliations
- University of Michigan (US)
- Corresponding author
- Meyerhoff, Mark E.
- Venue
- Biosensors and Bioelectronics
- Publisher
- Elsevier BV
- Published
- 2011-07
- Volume
- 26
- Issue
- 11
- Pages
- 4276-4282
- ISSN
- 0956-5663 (ISSN-L)
- PMC
- PMC3120931
- OpenAlex
- W2016496364
- Cited by
- 41
- References
- 42
- Citations by year
- 2024: 2 · 2023: 1 · 2022: 1 · 2021: 2 · 2020: 4 · 2019: 2 · 2018: 4 · 2017: 5 · 2016: 7 · 2015: 3 · 2014: 3 · 2013: 5 · 2012: 1
- FWCI
- 2.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Biosensors and Bioelectronics (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- U.S. Food and Drug Administration
- National Institute of Biomedical Imaging and Bioengineering (EB-000783, R01EB000783)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (R01HD015434)
- Topics
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Electrochemical sensors and biosensors
- Physical Sciences › Chemical Engineering › Bioengineering › Analytical Chemistry and Sensors
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Enzyme Catalysis and Immobilization
- Keywords
- glucose sensor, lactate sensor, nitric oxide release, PLGA coating, diazeniumdiolates, hemocompatibility, amperometric sensor, glucose oxidase, lactate oxidase, enzyme immobilization, thrombus formation, continuous glucose monitoring, implantable sensors, Clarke error grid
- MeSH terms
- Polylactic Acid-Polyglycolic Acid Copolymer, Animals, Biocompatible Materials, Equipment Design, Glucose, Humans, Materials Testing, Polyglycolic Acid, Rabbits, Blood Glucose Self-Monitoring, Biosensing Techniques, Lactic Acid, Nitric Oxide Donors
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
