Factors influencing the blood-brain barrier permeability

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Blood-Brain Barrier: From Physiology to Disease and Back

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Pericyte Loss and Microaneurysm Formation in PDGF-B-Deficient Mice

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Size-selective loosening of the blood-brain barrier in claudin-5–deficient mice

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Clearance systems in the brain—implications for Alzheimer disease

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Astrocytes induce blood–brain barrier properties in endothelial cells

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Neuroinflammation: friend and foe for ischemic stroke

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The human ATP-binding cassette (ABC) transporter superfamily

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VEGF enhances angiogenesis and promotes blood–brain barrier leakage in the ischemic brain

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Microglia development follows a stepwise program to regulate brain homeostasis

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Increased microvascular permeability and endothelial fenestration induced by vascular endothelial growth factor

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Central nervous system pericytes in health and disease

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Blood-brain barrier dysfunction and recovery after ischemic stroke

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Microglia: Scapegoat, saboteur, or something else?

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Inflammatory Mediators and Modulation of Blood–Brain Barrier Permeability

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Matrix metalloproteinases in the brain and blood–brain barrier: Versatile breakers and makers

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GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

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Developing nervous tissue induces formation of blood-brain barrier characteristics in invading endothelial cells: A study using quail-chick transplantation chimeras

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Alzheimer’s disease: A matter of blood–brain barrier dysfunction?

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Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wallPreprint

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Human iPSC-Derived Blood-Brain Barrier Chips Enable Disease Modeling and Personalized Medicine Applications

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Blood-brain barrier dysfunction in ischemic stroke: targeting tight junctions and transporters for vascular protection

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Pericyte recruitment during vasculogenic tube assembly stimulates endothelial basement membrane matrix formation

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Engaging neuroscience to advance translational research in brain barrier biology

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Brain barriers: Crosstalk between complex tight junctions and adherens junctions

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Microglia-derived TNF-α mediates endothelial necroptosis aggravating blood brain–barrier disruption after ischemic stroke

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Clathrin-independent pathways of endocytosis

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Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability

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Involvement of ROS in BBB dysfunction

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Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

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Crossing the Blood–Brain Barrier: Recent Advances in Drug Delivery to the Brain

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Specific role of tight junction proteins claudin-5, occludin and ZO-1 of the blood-brain barrier in a focal cerebral ischemic insult

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Pericytes and Neurovascular Function in the Healthy and Diseased Brain

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Anatomy and physiology of the blood-brain barrier

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Microglial Responses after Ischemic Stroke and Intracerebral Hemorrhage

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Regulation of blood-brain barrier integrity by microglia in health and disease: A therapeutic opportunity

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Targeting the transferrin receptor for brain drug delivery

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Occludin Phosphorylation and Ubiquitination Regulate Tight Junction Trafficking and Vascular Endothelial Growth Factor-induced Permeability

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Impaired Amino Acid Transport at the Blood Brain Barrier Is a Cause of Autism Spectrum Disorder

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Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

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Transmembrane proteins of the tight junctions at the blood–brain barrier: Structural and functional aspects

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Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy

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ABC transporter research: going strong 40 years on

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Matrix Metalloproteinase-9 Mediates Hypoxia-Induced Vascular Leakage in the Brain via Tight Junction Rearrangement

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Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

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Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-β in a Mouse Model of Alzheimer’s Disease

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Glucose Transporters at the Blood-Brain Barrier: Function, Regulation and Gateways for Drug Delivery

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Heparan sulfate proteoglycan as a plasma membrane carrier

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Factors controlling permeability of the blood–brain barrier

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Microglia–blood vessel interactions: a double-edged sword in brain pathologies

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Blood–brain barrier dysfunction developed during normal aging is associated with inflammation and loss of tight junctions but not with leukocyte recruitment

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Amyloid Beta induces oxidative stress-mediated blood-brain barrier changes in capillary amyloid angiopathy

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Fluid and ion transfer across the blood–brain and blood–cerebrospinal fluid barriers; a comparative account of mechanisms and roles

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Predominant phagocytic activity of resident microglia over hematogenous macrophages following transient focal cerebral ischemia: an investigation using green fluorescent protein transgenic bone marrow chimeric mice

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Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

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Barrier function in the peripheral and central nervous system—a review

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Blood-brain barrier permeability and physical exercise

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Dual Roles of Astrocyte-Derived Factors in Regulation of Blood-Brain Barrier Function after Brain Damage

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Endothelial Smad4 Maintains Cerebrovascular Integrity by Activating N-Cadherin through Cooperation with Notch

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Brain Microvascular Pericytes in Vascular Cognitive Impairment and Dementia

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Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?

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Multidrug Resistance Protein MRP2 Contributes to Blood-Brain Barrier Function and Restricts Antiepileptic Drug Activity

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PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation

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Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood–brain barrier breakdown

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The Extracellular Matrix Protein Laminin α2 Regulates the Maturation and Function of the Blood–Brain Barrier

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Zonula Occludens-1 Function in the Assembly of Tight Junctions in Madin-Darby Canine Kidney Epithelial Cells

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Differential expression of receptors mediating receptor-mediated transcytosis (RMT) in brain microvessels, brain parenchyma and peripheral tissues of the mouse and the human

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Role of the Blood–Brain Barrier in the Nutrition of the Central Nervous System

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Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-α in the Rat

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Neuron-Glial Interactions in Blood-Brain Barrier Formation

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Estrogen protects the blood–brain barrier from inflammation-induced disruption and increased lymphocyte trafficking

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Astrocyte-mediated control of cerebral microcirculation

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In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization

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Oligodendrocyte Precursor Cells Support Blood-Brain Barrier Integrity via TGF-β Signaling

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Angiogenesis and Blood-Brain Barrier Permeability in Vascular Remodeling after Stroke

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Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation

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Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes

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Interaction between blood-brain barrier and glymphatic system in solute clearance

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Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier

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Receptor-mediated transcytosis of transferrin through blood-brain barrier endothelial cells

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The NMDA and AMPA/KA Receptors are Involved in Glutamate-Induced Alterations of Occludin Expression and Phosphorylation in Brain Endothelial Cells

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The blood–brain-barrier in multiple sclerosis: Functional roles and therapeutic targeting

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Autophagy- and MMP-2/9-mediated Reduction and Redistribution of ZO-1 Contribute to Hyperglycemia-increased Blood–Brain Barrier Permeability During Early Reperfusion in Stroke

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Neurobarrier Coupling in the Brain: A Partner of Neurovascular and Neurometabolic Coupling?

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Blood–brain barrier breakdown and repair by Src after thrombin‐induced injury

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Ultracytochemical characterization of anionic sites in the wall of brain capillaries

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Bridging the gap between the immune and glutamate hypotheses of schizophrenia and major depression: Potential role of glial NMDA receptor modulators and impaired blood–brain barrier integrity

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Leukotrienes increase blood‐brain barrier permeability following intraparenchymal injections in rats

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Inhibition of Hypoxia-Induced Increase of Blood-Brain Barrier Permeability by YC-1 through the Antagonism of HIF-1α Accumulation and VEGF Expression

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Blood-Brain Barrier and Breast Cancer Resistance Protein: A Limit to the Therapy of CNS Tumors and Neurodegenerative Diseases

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Tyrosine Phosphatase PTPRJ/DEP-1 Is an Essential Promoter of Vascular Permeability, Angiogenesis, and Tumor Progression

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Burns Impair Blood-Brain Barrier and Mesenchymal Stem Cells Can Reverse the Process in Mice

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Dl-3-N-Butylphthalide Alleviates the Blood–Brain Barrier Permeability of Focal Cerebral Ischemia Reperfusion in Mice

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Hydrogen sulfide attenuates hyperhomocysteinemia-induced blood-brain barrier permeability by inhibiting MMP-9

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Current Advances in Studying Clinically Relevant Transporters of the Solute Carrier (SLC) Family by Connecting Computational Modeling and Data Science

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Receptor Ligand-Free Mesoporous Silica Nanoparticles: A Streamlined Strategy for Targeted Drug Delivery across the Blood–Brain Barrier

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Exosome-powered neuropharmaceutics: unlocking the blood-brain barrier for next-gen therapies

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Breaking the Barrier: The Role of Proinflammatory Cytokines in BBB Dysfunction

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Targeting Cytokine-Mediated Inflammation in Brain Disorders: Developing New Treatment Strategies

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Enhancing drug penetration in solid tumors via nanomedicine: Evaluation models, strategies and perspectives

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Complex in vitro model: A transformative model in drug development and precision medicine

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The Postbiotic Properties of Butyrate in the Modulation of the Gut Microbiota: The Potential of Its Combination with Polyphenols and Dietary Fibers

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Unraveling the complexity of human brain: Structure, function in healthy and disease states

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High altitude hypoxia and oxidative stress: The new hope brought by free radical scavengers

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Microbial-Derived Tryptophan Metabolites and Their Role in Neurological Disease: Anthranilic Acid and Anthranilic Acid Derivatives

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Exploring the Potential Impact of GLP-1 Receptor Agonists on Substance Use, Compulsive Behavior, and Libido: Insights from Social Media Using a Mixed-Methods Approach

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Multifunctional Nanotheranostics for Overcoming the Blood–Brain Barrier

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Digital alchemy: Exploring the pharmacokinetic and toxicity profiles of selected coumarin-heterocycle hybrids

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Crosstalk between peripheral inflammation and brain: Focus on the responses of microglia and astrocytes to peripheral challenge

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Astrocyte in Neurological Disease: Pathogenesis and Therapy

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Iron and Targeted Iron Therapy in Alzheimer’s Disease

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Intrathecal Therapies for Neurodegenerative Diseases: A Review of Current Approaches and the Urgent Need for Advanced Delivery Systems

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Could a Mediterranean Diet Modulate Alzheimer’s Disease Progression? The Role of Gut Microbiota and Metabolite Signatures in Neurodegeneration

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Nanotechnology to Overcome Blood–Brain Barrier Permeability and Damage in Neurodegenerative Diseases

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Maresin1 improves hippocampal neuroinflammation and cognitive function in septic rats by activating the SLC7A11/GPX4 ferroptosis signaling pathway

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Modernizing Neuro-Oncology: The Impact of Imaging, Liquid Biopsies, and AI on Diagnosis and Treatment

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Computational Modeling of Pharmaceuticals with an Emphasis on Crossing the Blood–Brain Barrier

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Hydrogel-Based Therapies for Ischemic and Hemorrhagic Stroke: A Comprehensive Review

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Beyond the Walls of Troy: A Scoping Review on Pharmacological Strategies to Enhance Drug Delivery Across the Blood–Brain Barrier and Blood–Tumor Barrier

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Understanding the Blood-Brain Barrier: From Physiology to Pathology

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A Novel Quercetin Encapsulated Glucose Modified Liposome and Its Brain-Target Antioxidative Neuroprotection Effects

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Recent Update on Pharmacokinetics and Drug Metabolism in CNS-based Drug Discovery

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Current Treatment of Melanoma Brain Metastases

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Mechanistic Intimate Insights into the Role of Hydrogen Sulfide in Alzheimer’s Disease: A Recent Systematic Review

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Exploring novel roles of lipid droplets and lipid metabolism in regulating inflammation and blood–brain barrier function in neurological diseases

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Potential Roles of Natural Antioxidants in Modulating Neurodegenerative Disease Pathways

Oyovwi, M. O., Agbonifo‐Chijiokwu, E., Ben‐Azu, B., Atere, A. D., Joseph, G. U., Godsday, O. U., & Udi, O. A. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-04874-w · Cited by 20 · see citing works

Detection and modulation of neurodegenerative processes using graphene-based nanomaterials: Nanoarchitectonics and applications

Tiwari, P., & Tiwari, S. (2022) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2022.102824 · Cited by 19 · see citing works

MiRNAs as potential therapeutic targets and biomarkers for non-traumatic intracerebral hemorrhage

Фанилевич, Г. И., Beylerli, O., & Zhao, B. (2024) · Biomarker Research · doi:10.1186/s40364-024-00568-y · Cited by 22 · see citing works

Potential mechanisms of Treponema pallidum breaching the blood-brain barrier

Zhou, Y., Xie, Y., & Xu, M. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117478 · Cited by 18 · see citing works

Application of Novel Drug‐Delivery Strategies in Neurological Disorders

Li, C., Yao, S., Li, Z., & Gao, Y. (2025) · Advanced Materials · doi:10.1002/adma.202503646 · Cited by 18 · see citing works

Role of Blood-Brain barrier in bacterial translocation

Aborode, A. T., Adesola, R. O., Scott, G. Y., Adepoju, V. A., Akan, O. D., Ogunyemi, A. D., Adetunji, A. P.-G., Arogundade, F. Q., Kwaku, S. D., Emmanuel, A. O., et al. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.06.037 · Cited by 18 · see citing works

The Breakdown of Neurovascular Barriers: Molecular Mechanisms of Tight Junction Dysfunction

Gopal, S. S., Kaur, M., Lanzkron, S., & Srivastava, A. K. (2025) · Molecular Neurobiology · doi:10.1007/s12035-025-05592-z · Cited by 19 · see citing works

Molecular and biophysical remodeling of the blood–brain barrier in glioblastoma: mechanistic drivers of tumor–neurovascular crosstalk

Abikenari, M. A., Sjöholm, M., Liu, J., Nageeb, G., Ha, J. H., Wu, J. Y., Ren, A. L., Sayadi, J. J., Lim, J., Cho, K. B., et al. (2025) · Frontiers in Physics · doi:10.3389/fphy.2025.1723329 · Cited by 19 · see citing works

Melatonin and brain barriers: The protection conferred by melatonin to the blood-brain barrier and blood-cerebrospinal fluid barrier

Mineiro, R., Cardoso, M. R., Duarte, A. C., Santos, C. R. A., Cipolla‐Neto, J., do Amaral, F. G., Costa, D. R. B., & Quintela, T. (2024) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2024.101158 · Cited by 17 · see citing works

Naringenin Protected Against Blood Brain Barrier Breakdown after Ischemic Stroke through GSK-3β/ β-Catenin Pathway

Yang, Y., Li, L., Liang, Y., Xia, Y., Fang, Z., & Wang, S. (2024) · Neurochemical Research · doi:10.1007/s11064-024-04259-w · Cited by 17 · see citing works

Virus-Based Biological Systems as Next-Generation Carriers for the Therapy of Central Nervous System Diseases

Nowak, I., Madej, M., Secemska, J., Sarna, R., & Strzałka‐Mrozik, B. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15071931 · Cited by 17 · see citing works

The Recent Applications of PLGA-Based Nanostructures for Ischemic Stroke

Yan, J., Huang, L., Feng, J., & Yang, X. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15092322 · Cited by 17 · see citing works

Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition

Dichiara, M., Cosentino, G., Giordano, G., Pasquinucci, L., Marrazzo, A., Costanzo, G., & Amata, E. (2023) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2023.2294118 · Cited by 17 · see citing works

Advancing through the blood-brain barrier: mechanisms, challenges and drug delivery strategies

Vargas, R., Martínez-Martínez, N., Lizano-Barrantes, C., Molina, J. A. P., García‐Montoya, E., Pérez‐Lozano, P., Suñé-Negre, J. M., Suñé, C., & Suñé-Pou, M. (2025) · ADMET & DMPK · doi:10.5599/admet.2988 · Cited by 17 · see citing works

Electroacupuncture-modulated extracellular ATP levels in prefrontal cortex ameliorated depressive-like behavior of maternal separation rats

Zheng, Y., Pan, L., Jiang, H., Yan, J., Xia, Y., Lin, C., Chen, X., Zhao, Q., Zeng, Q., Julikezi, M., et al. (2023) · Behavioural Brain Research · doi:10.1016/j.bbr.2023.114548 · Cited by 16 · see citing works

Targeting Non-Coding RNA for CNS Injuries: Regulation of Blood-Brain Barrier Functions

Zhang, L., Bai, W., Sun, L., Lin, Y., & Tian, M. (2023) · Neurochemical Research · doi:10.1007/s11064-023-03892-1 · Cited by 15 · see citing works

Itaconate: A promising precursor for treatment of neuroinflammation associated depression

Liu, R., Gong, Y., Xia, C., Cao, Y., Zhao, C., & Zhou, M. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115521 · Cited by 16 · see citing works

Cubosomes: evolving platform for intranasal drug delivery of neurotherapeutics

Gawarkar‐Patil, P., Mahajan, B., Pawar, A., & Dhapte-Pawar, V. S. (2024) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-024-00665-7 · Cited by 15 · see citing works

Nature vs. Manmade: Comparing Exosomes and Liposomes for Traumatic Brain Injury

Hennigan, K., & Lavik, E. (2023) · The AAPS Journal · doi:10.1208/s12248-023-00849-8 · Cited by 14 · see citing works

Serum Zonula Occludens-1 and Claudin-5 Levels in Patients with Insomnia Disorder: A Pilot Study

Fan, M., Deng, F., Rui, T., Cai, Y., Zhang, X., Li, H., Xiang, T., & Pan, J. (2023) · Nature and Science of Sleep · doi:10.2147/nss.s424756 · Cited by 15 · see citing works

The battle of lipid-based nanocarriers against blood-brain barrier: a critical review

Abla, K. K., & Mehanna, M. M. (2023) · Journal of drug targeting · doi:10.1080/1061186x.2023.2247583 · Cited by 15 · see citing works

MicroRNA-522-3p promotes brain metastasis in non-small cell lung cancer by targeting Tensin 1 and modulating blood-brain barrier permeability

Liu, Q., Bao, H., Zhang, S., Li, C., Sun, G., Sun, X., Fu, T., Wang, Y., & Liang, P. (2024) · Experimental Cell Research · doi:10.1016/j.yexcr.2024.114199 · Cited by 13 · see citing works

Metal Armor-Decorated Neutrophil Micromotors with Self-Propelled and Targeting Function for Brain Injury Precise Therapy

Lan, D., Wang, H., Wang, D., Wang, S., Mi, J., Gui, H., Cai, X., Xia, Y., Fan, H., Cao, H., et al. (2025) · ACS Nano · doi:10.1021/acsnano.5c05075 · Cited by 14 · see citing works

Discovery of Novel Tryptanthrin Derivatives with Benzenesulfonamide Substituents as Multi-Target-Directed Ligands for the Treatment of Alzheimer’s Disease

Wang, G., Du, J., Ma, J., Liu, P., Xing, S., Xia, J., Dong, S., & Li, Z. (2023) · Pharmaceuticals · doi:10.3390/ph16101468 · Cited by 12 · see citing works

Blood-cerebrospinal fluid barrier permeability of metals/metalloids and its determinants in pediatric patients

Wu, W., Ruan, X., Gu, C., Luo, D., Ye, J., Diao, F., Wu, L., & Luo, M. (2023) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2023.115599 · Cited by 12 · see citing works

Functional Brain Changes Following Burn Injury: A Narrative Review

Rowe, G., Allahham, A., Edgar, D. W., Rurak, B. K., Fear, M. W., Wood, F. M., & Vallence, A. (2023) · Neurorehabilitation and neural repair · doi:10.1177/15459683231215331 · Cited by 12 · see citing works

Investigating the therapeutic effects of nimodipine on vasogenic cerebral edema and blood-brain barrier impairment in an ischemic stroke rat model

Shadman, J., Panahpour, H., Alipour, M. R., Salimi, A., Shahabi, P., & Azar, S. S. (2024) · Neuropharmacology · doi:10.1016/j.neuropharm.2024.110054 · Cited by 12 · see citing works

Improving glioma drug delivery: A multifaceted approach for glioma drug development

Yonk, M. G., Lim, M. A., Thompson, C. M., Tora, M. S., Lakhina, Y., Du, Y., Hoang, K. B., Molinaro, A. M., Boulis, N. M., Hassaneen, W., et al. (2024) · Pharmacological Research · doi:10.1016/j.phrs.2024.107390 · Cited by 12 · see citing works

NR4A2 attenuates early brain injury after intracerebral hemorrhage by promoting M2 microglial polarization via TLR4/TRAF6/NF-κB pathway inhibition

Hu, D., Huang, C., Tang, L. Y., Lei, J., Wang, J., Hu, W., Chen, M., Song, S., Lü, L., & Xu, P. (2025) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-025-05755-0 · Cited by 12 · see citing works

Recent advances in cell-based in vitro models for predicting drug permeability across brain, intestinal, and pulmonary barriers

Eltanameli, B., Piñeiro-Llanes, J., & Cristofoletti, R. (2024) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2024.2366390 · Cited by 12 · see citing works

Andrographolide attenuates PM2.5-induced blood–brain barrier damage via antioxidant and PI3K/AKT/mTOR/NRF2 pathways

Kang, K., Zhang, Y., Geng, Y., Wang, D., & Zheng, P. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114764 · Cited by 11 · see citing works

Progress in Research on the Mechanism of GABA in Improving Sleep

Li, S., Li, Y., Xue, C., Zhang, Y., Tong, T., Ouyang, Z., Liu, D., Cai, J., & Sun, H. (2025) · Foods · doi:10.3390/foods14223856 · Cited by 11 · see citing works

Nanoparticles in CNS Therapeutics: Pioneering Drug Delivery Advancements

Nayak, U. Y., Halagali, P., Panchal, K. N., Tippavajhala, V. K., Mudgal, J., Radhakrishnan, R. A., & Manikkath, J. (2024) · Current Pharmaceutical Design · doi:10.2174/0113816128328722240828184410 · Cited by 11 · see citing works

Bone-derived PDGF-BB enhances hippocampal non-specific transcytosis through microglia-endothelial crosstalk in HFD-induced metabolic syndrome

Liu, G., Shu, W., Chen, Y., Fu, Y., Fang, S., Zheng, H., Cheng, W., Lin, Q., Hu, Y., Jiang, N., et al. (2024) · Journal of Neuroinflammation · doi:10.1186/s12974-024-03097-5 · Cited by 10 · see citing works

Characterization of the Components and Metabolites of Achyranthes Bidentata in the Plasma and Brain Tissue of Rats Based on Ultrahigh Performance Liquid Chromatography–High-Resolution Mass Spectrometry (UHPLC–HR-MS)

Wu, M., Yang, P., Wang, J., Yang, R., Chen, Y., Liu, K., Yuan, Y., & Zhang, L. (2024) · Molecules · doi:10.3390/molecules29122840 · Cited by 10 · see citing works

Neurovascular dysfunction in psychiatric disorders: Underlying mechanisms and therapeutic approaches

Sanches, E. S., Simões, D. M., Baptista, F. I., & Silva, A. P. (2024) · European Journal of Clinical Investigation · doi:10.1111/eci.14319 · Cited by 10 · see citing works

Deciphering the Blood–Brain Barrier Paradox in Brain Metastasis Development and Therapy

Peters, J. J., Teng, C., Peng, K., & Li, X. (2025) · Cancers · doi:10.3390/cancers17020298 · Cited by 11 · see citing works

Mechanisms of HIV-mediated blood-brain barrier compromise and leukocyte transmigration under the current antiretroviral era

Hernandez, C., Górska, A. M., & Eugenín, E. A. (2024) · iScience · doi:10.1016/j.isci.2024.109236 · Cited by 10 · see citing works

Advancements in nanotheranostics for glioma therapy

Sahoo, L., Paikray, S. K., Tripathy, N. S., Fernandes, D. A., & Dilnawaz, F. (2024) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-024-03559-w · Cited by 12 · see citing works

Cyanomethyl Vinyl Ethers Against Naegleria fowleri

Chao-Pellicer, J., Arberas-Jiménez, I., Delgado‐Hernández, S., Sifaoui, I., Tejedor, D., García‐Tellado, F., Piñero, J. E., & Lorenzo‐Morales, J. (2023) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.3c00110 · Cited by 10 · see citing works

circRNAs as Epigenetic Regulators of Integrity in Blood–Brain Barrier Architecture: Mechanisms and Therapeutic Strategies in Multiple Sclerosis

D'Aversa, E., Salvatori, F., Vaccarezza, M., Antonica, B., Grisafi, M., Singh, A., Secchiero, P., Zauli, G., Tisato, V., & Gemmati, D. (2024) · Cells · doi:10.3390/cells13161316 · Cited by 10 · see citing works

From Obesity to Mitochondrial Dysfunction in Peripheral Tissues and in the Central Nervous System

Marino, F., Petrella, L., Cimmino, F., Pizzella, A., Monda, A., Allocca, S., Rotondo, R., D’Angelo, M., Musco, N., Iommelli, P., et al. (2025) · Biomolecules · doi:10.3390/biom15050638 · Cited by 10 · see citing works

Focused transcranial ultrasound stimulation: a breakthrough approach to treating brain disorders

Vanneste, S., Reynolds, J. N. J., & Ridder, D. D. (2025) · Expert Review of Medical Devices · doi:10.1080/17434440.2025.2563618 · Cited by 9 · see citing works

Navigating the Central Nervous System (CNS): A Pharmacokinetic Approach to the Treatment of CNS Tumors, Glioblastoma Multiforme (GBM), in Particular

Bartusik‐Aebisher, D., Tylutki, J., Tylutki, M., Leś, D., & Aebisher, D. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199418 · Cited by 9 · see citing works

Carbon Dots for Next-Generation Cancer Theranostics: From Advanced Imaging to Targeted Therapy

Patyal, R., Warjurkar, K., & Sharma, V. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.5c01797 · Cited by 9 · see citing works

Crossing the Blood–Brain Barrier with Molecularly Imprinted Polymeric Nanocarriers: An Emerging Frontier in Brain Disease Therapy

De, R., Shi, S., & Kim, K. (2025) · Advanced Science · doi:10.1002/advs.202517004 · Cited by 9 · see citing works

Plant-derived extracellular vesicles for itraconazole delivery across the blood-brain barrier for potential glioblastoma treatment

Bhom, N., Ramburrun, P., Somandi, K., & Choonara, Y. E. (2026) · Scientific Reports · doi:10.1038/s41598-025-33187-0 · Cited by 9 · see citing works

The role of astrocytes in Alzheimer's disease: Pathophysiology, biomarkers, and therapeutic potential

Abedin, M. J., & Kastanenka, K. V. (2026) · Journal of Alzheimer s Disease · doi:10.1177/13872877251411561 · Cited by 9 · see citing works

Time-dependent neurovascular unit dysfunction in ischemic stroke: mechanisms of neurovascular uncoupling and its clinical impact

Lahariya, R., Sinha, M., Kumari, B., Subramanian, K. V., & Anand, G. S. (2026) · International Journal of Neuroscience · doi:10.1080/00207454.2026.2627246 · Cited by 9 · see citing works

Glutathione transporter as a target for brain drug delivery

Guan, X. (2024) · Medicinal Chemistry Research · doi:10.1007/s00044-024-03225-z · Cited by 8 · see citing works

Effect of Specific mode electroacupuncture stimulation combined with NGF during the ischaemic stroke: Study protocol for a randomized controlled trial

Dai, M., Zhao, Y., Jia, Z., Xu, S., Xu, N., Wu, X. W., Liu, J., Wu, L., Yu, K., & Lin, X. (2024) · Clinics · doi:10.1016/j.clinsp.2024.100451 · Cited by 8 · see citing works

Blood-brain barrier alterations as an initiator of brain metastasis from lung cancer: a new take on an old story

Jian-fen, W., Wu, H., Zhou, F., Wang, Y., Wang, C., & Ji, J. (2025) · Cancer Gene Therapy · doi:10.1038/s41417-025-00916-6 · Cited by 8 · see citing works

Factors controlling permeability of the blood–brain barrier

Almutairi, M. M., Chen, G., Xu, Y. G., Chang, Y., & Shi, H. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2050-8 · Cited by 308 · see citing works

Inflammatory Factors Regulating the Blood-brain Barrier

DIETRICEH, W. D. (2003) · CRC Press eBooks · doi:10.1201/9781482298185-11 · Cited by 2 · see citing works

Mechanisms of transport across the blood–brain barrier

Das, N. G., & Das, S. K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33623-2.00019-2 · Cited by 1 · see citing works

Molecular and cellular permeability control at the blood-brain barrier

Gloor, S. M., Wachtel, M., Bolliger, M. F., Ishihara, H., Landmann, R., & Frei, K. (2001) · Brain Research Reviews · doi:10.1016/s0165-0173(01)00102-3 · Cited by 244 · see citing works

From Blood-to-Brain: Regulating the Permeability of the Blood-Brain Barrier

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