Overview of orofacial pain: epidemiology and gender differences in orofacial pain
Abstract
Chronic orofacial pain is a prevalent problem that encompasses numerous disorders with diverse causes and presenting symptoms. Compared with men, women of reproductive age seek treatment for orofacial pain conditions, as well as other chronic pain disorders more frequently. Important issues have been raised regarding gender and sex differences in genetic, neurophysiologic, and psychosocial aspects of pain sensitivity and analgesia. Efforts to improve our understanding of qualitative sex differences in pain modulation signify a promising step toward developing more tailored approaches to pain management.
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Consistent with the Cognitive Behavioral Model of chronic pain, evidence suggests that pain catastrophizing influences pain-related disability through fear of pain.
“Consistent with the Cognitive Behavioral Model of chronic pain, there is evidence to suggest that pain catastrophizing influences pain-related disability via fear of pain 25, 335, 336.”
From Evaluating psychosocial contributions to chronic pain outcomes (2018) · cites this paper as [335]
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Pyridin-2(1H)one derivatives - a new class of therapeutics for trigeminal pain
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Delta-opioïd receptor : a potential new target for migraine and headache therapies
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Maulina, T., Shafira, M., Wulansari, D., & Nurwiadh, A. (2020) · The Open Dentistry Journal · doi:10.2174/1874210602014010317
- Authors
- Shinal, R. M., & Fillingim, R. B.
- Affiliations
- University of Florida Health (US)
- Corresponding author
- Fillingim, Roger B.
- ORCID
- Fillingim, Roger B.
- Venue
- Dental Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2007-01
- Volume
- 51
- Issue
- 1
- Pages
- 1-18
- ISSN
- 0011-8532 (ISSN-L)
- OpenAlex
- W2071564810
- Cited by
- 80
- References
- 156
- Citations by year
- 2025: 5 · 2024: 2 · 2023: 4 · 2022: 1 · 2021: 8 · 2020: 5 · 2019: 4 · 2018: 5 · 2017: 4 · 2016: 1 · 2015: 4 · 2014: 7 · 2013: 6 · 2012: 3
- FWCI
- 1.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Dental Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Health Professions › Complementary and Manual Therapy › Temporomandibular Joint Disorders
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Sex and Gender in Healthcare
- Health Sciences › Medicine › Physiology › Pain Mechanisms and Treatments
- Keywords
- orofacial pain, chronic pain, sex differences, gender differences, epidemiology, pain sensitivity, analgesia, pain modulation, women of reproductive age, pain management
- MeSH terms
- Analgesia, Animals, Brain, Brain Neoplasms, Disease Models, Animal, Facial Neuralgia, Facial Pain, Female, Humans, Male, Sex Factors, Pain Threshold
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