The DOI matches its Crossref record; 20 of the 20 references it cites were found in a registry or an index.
The Hormonal Control of Food Intake
Open accessAbstract
Numerous circulating peptides and steroids produced in the body influence appetite through their actions on the hypothalamus, the brain stem, and the autonomic nervous system. These hormones come from three major sites-fat cells, the gastrointestinal tract, and the pancreas. In this Review we provide a synthesis of recent evidence concerning the actions of these hormones on food intake.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Sakurai, T., Amemiya, A., Ishii, M., Matsuzaki, I., Chemelli, R. M., Tanaka, H., Williams, S. C., Richardson, J. A., Kozlowski, G. P., Wilson, S., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)80949-6 · Cited by 5,501
Leptin and the regulation of body weight in mammals
Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405
Hypothalamic regulation of sleep and circadian rhythms
Saper, C. B., Scammell, T. E., & Lu, J. (2005) · Nature · doi:10.1038/nature04284 · Cited by 2,804
Anatomy and regulation of the central melanocortin system
Cone, R. D. (2005) · Nature Neuroscience · doi:10.1038/nn1455 · Cited by 1,583
Leptin-Replacement Therapy for Lipodystrophy
Oral, E. A., Simha, V., Ruiz, E., Andewelt, A., Premkumar, A., Snell, P., Wagner, A. J., DePaoli, A. M., Reitman, M. L., Taylor, S. I., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012437 · Cited by 1,247 · cited 1×
“, 2002), has dramatic effects on the metabolic state of patients with lipodystrophy (a metabolic disorder characterized by selective loss of body fat and low leptin levels) (Oral et al., 2002), and shows promise as a therapeutic/diagnostic agent for weight-related reproductive disorders (Welt et al.”
Interleukin-6-deficient mice develop mature-onset obesity
Wallenius, V., Wallenius, K., Ahrén, B., Rudling, M., Carlsten, H., Dickson, S. L., Ohlsson, C., & Jansson, J.-O. (2002) · Nature Medicine · doi:10.1038/nm0102-75 · Cited by 1,213
Rapid Rewiring of Arcuate Nucleus Feeding Circuits by Leptin
Pinto, S., Roseberry, A. G., Liu, H., Diano, S., Shanabrough, M., Cai, X., Friedman, J. M., & Horvath, T. L. (2004) · Science · doi:10.1126/science.1089459 · Cited by 987 · cited 1×
“By studying the electrophysiological activity in neurons from ob/ob mice, it was shown that leptin deficiency markedly changes synaptic inputs to arcuate neurons, increasing excitatory inputs on NPY/AgRP neurons but decreasing excitatory inputs to POMC neurons (Pinto et al., 2004).”
Roux, C. W. L., Aylwin, S. J. B., Batterham, R. L., Borg, C. M., Coyle, F., Prasad, V., Shurey, S., Ghatei, M. A., Patel, A. G., & Bloom, S. R. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000183349.16877.84 · Cited by 985
Recombinant human leptin in women with hypothalamic amenorrhea
Welt, C. K., Chan, J. L., Bullen, J., Murphy, R., Smith, P., DePaoli, A. M., Karalis, A., & Mantzoros, C. S. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040388 · Cited by 908
Cited by
Reward, dopamine and the control of food intake: implications for obesity
Volkow, N. D., Wang, G.-J., & Baler, R. D. (2011) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2010.11.001 · Cited by 1,400
Sirt1 protects against high-fat diet-induced metabolic damage
Pfluger, P. T., Herranz, D., Velasco-Miguel, S., Serrano, M., & Tschöp, M. H. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0802917105 · Cited by 818
The Melanocortin-4 Receptor: Physiology, Pharmacology, and Pathophysiology
Tao, Y.-X. (2010) · Endocrine Reviews · doi:10.1210/er.2009-0037 · Cited by 531
Rinaman, L. (2010) · Brain Research · doi:10.1016/j.brainres.2010.03.059 · Cited by 311
“…from hypothalamus to caudal brainstem provide critical control over the initiation and termination of food intake and feeding-related autonomic adjustments (Berthoud, 2002; Berthoud et al., 2006; Coll et al., 2007; Smith, 2000; Smith, 2003; Woods and D'Alessio, 2008; Zheng et al., 2005).”
BackgroundHyperleptinemia Is Required for the Development of Leptin Resistance
Knight, Z. A., Hannan, K. S., Greenberg, M. L., & Friedman, J. M. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011376 · Cited by 311
Neuroinflammation and neurodegeneration in overnutrition-induced diseases
Cai, D. (2013) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2012.11.003 · Cited by 256
Zhang, G., Bai, H., Zhang, H., Dean, C., Wu, Q., Li, J., Guariglia, S., Meng, Q., & Cai, D. (2011) · Neuron · doi:10.1016/j.neuron.2010.12.036 · Cited by 208
TGF-b superfamily cytokine MIC-1/GDF15 is a physiological appetite and body weight regulator
Tsai, V. W.-W., Macia, L., Johnen, H., Kuffner, T., Manadhar, R., Jørgensen, S. B., Lee-Ng, K. K. M., Zhang, H. P., Wu, L., Marquis, C. P., et al. (2013) · PLoS ONE · doi:10.1371/journal.pone.0055174 · Cited by 188
Zhang, G., & Cai, D. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00196.2011 · Cited by 171
The maternal deprivation animal model revisited.
Marco, E. M., Llorente, R., López-Gallardo, M., Mela, V., Llorente-Berzal, Á., Prada, C., & Viveros, M.-P. (2015) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2015.01.015 · Cited by 132
Food‐Related Odor Probes of Brain Reward Circuits During Hunger: A Pilot fMRI Study
Bragulat, V., Dzemidzic, M., Bruno, C., Cox, C. A., Talavage, T., Considine, R. V., & Kareken, D. A. (2010) · Obesity · doi:10.1038/oby.2010.57 · Cited by 128
Neuronal regulation of homeostasis by nutrient sensing
Lam, T. K. T. (2010) · Nature Medicine · doi:10.1038/nm0410-392 · Cited by 125
The role of gut hormone peptide YY in energy and glucose homeostasis: Twelve years on
Manning, S., & Batterham, R. L. (2014) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021113-170404 · Cited by 124
Quantifying the Eating Abnormalities in Frontotemporal Dementia
Ahmed, R. M., Irish, M., Kam, J., van Keizerswaard, J., Bartley, L., Samaras, K., Hodges, J. R., & Piguet, O. (2014) · JAMA Neurology · doi:10.1001/jamaneurol.2014.1931 · Cited by 120
Townsend, K. L., Suzuki, R., Huang, T. L., Jing, E., Schulz, T. J., Lee, K., Taniguchi, C. M., Espinoza, D. O., McDougall, L. E., Zhang, H., et al. (2012) · The FASEB Journal · doi:10.1096/fj.11-199067 · Cited by 105
Yadav, V. K., Oury, F., Tanaka, K. F., Thomas, T., Wang, Y., Cremers, S., Hen, R., Krust, A., Chambon, P., & Karsenty, G. (2011) · Journal of Experimental Medicine · doi:10.1084/jem.20101940 · Cited by 96
Physiological changes in neurodegeneration—mechanistic insights and clinical utility
Ahmed, R. M., Ke, Y. D., Vucic, S., Ittner, L. M., Seeley, W., Hodges, J. R., Piguet, O., Halliday, G., & Kiernan, M. C. (2018) · Nature Reviews Neurology · doi:10.1038/nrneurol.2018.23 · Cited by 91
de Souza, F. S. J., Nasif, S., López-Leal, R., Levi, D. H., Low, M. J., & Rubinsten, M. (2011) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2010.10.114 · Cited by 75
O'Gorman, C. S., Simoneau-Roy, J., Pencharz, P., MacFarlane, J., MacLusky, I., Narang, I., Adeli, K., Daneman, D., & Hamilton, J. (2010) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2009-2003 · Cited by 72
Huang, H., Xu, Y., & van den Pol, A. N. (2011) · Journal of Neurophysiology · doi:10.1152/jn.00740.2010 · Cited by 70
Peptide hormones regulating appetite—focus on neuroimaging studies in humans
Schloegl, H., Percik, R., Horstmann, A., Villringer, A., & Stumvoll, M. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1154 · Cited by 70
Wiss, D. A., Criscitelli, K., Gold, M., & Avena, N. (2017) · Appetite · doi:10.1016/j.appet.2016.12.019 · Cited by 53
Yasrebi, A., Rivera, J. A., Krumm, E. A., Yang, J. A., & Roepke, T. A. (2017) · Endocrinology · doi:10.1210/en.2016-1535 · Cited by 40
Metadata
- Authors
- Coll, A. P., Farooqi, I. S., & O'Rahilly, S.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2007-04
- Volume
- 129
- Issue
- 2
- Pages
- 251-262
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2101782891
- Cited by
- 605
- References
- 20
- FWCI
- 19.32
- Type
- journal article
- Language
- en
- Open access
- hybrid
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.