The Hallmarks of Aging
Cited by (15,681)
Items 501–600 of 15,681
- Mitochondrial sirtuins, metabolism, and agingZhejun Ji, Guang‐Hui Liu, Jing Tao Qu · 2021 · Journal of genetics and genomics/Journal of Genetics and Genomics
- Klotho, Aging, and the Failing KidneySarah J Buchanan, Emilie Combet, Peter Stenvinkel, Paul G. Shiels · 2020 · Frontiers in Endocrinology
- Fibrosis: ultimate and proximate causesVictor John Thannickal, Yong Zhou, Amit Gaggar, Steven R. Duncan · 2014 · Journal of Clinical Investigation
- A Narrative Review on Plasminogen Activator Inhibitor-1 and Its (Patho)Physiological Role: To Target or Not to Target?Machteld Sillen, Paul J. Declerck · 2021 · International Journal of Molecular Sciences
- Inflammation and premature aging in advanced chronic kidney diseaseJeroen Peter Kooman, Marijke J.E. Dekker, Len A. Usvyat, Peter Kotanko, Frank M. VAN DER SANDE, Casper G. Schalkwijk, Paul G. Shiels, Peter Stenvinkel · 2017 · American Journal of Physiology-Renal Physiology
- A Review of Single-Cell RNA-Seq Annotation, Integration, and Cell–Cell CommunicationChangde Cheng, Wenan Chen, Hongjian Jin, Xiang 'Anthony' Chen · 2023 · Cells
- Obesity and aging: Molecular mechanisms and therapeutic approachesAna L. Santos, Sanchari Sinha · 2021 · Ageing Research Reviews
- Challenges in measuring and understanding biological noiseEling, Nils, Morgan, Michael D., Marioni, John C. · 2019 · Nature Reviews Genetics
- Pathogenesis of COVID-19-induced ARDS: implications for an ageing populationTorres Acosta, Manuel A., Singer, Benjamin D. · 2020 · European Respiratory Journal
- Keeping the senescence secretome under control: molecular reins on the senescence-associated secretory phenotype.Malaquin, Nicolas, Martinez, Aurélie, Rodier, Francis · 2016 · Experimental Gerontology
- Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged MiceSaccon, Tatiana Dandolini, Nagpal, Ravinder, Yadav, Hariom, Cavalcante, Marcelo Borges, Nunes, Allancer Divino de Carvalho, Schneider, Augusto, Gesing, Adam, Hughes, Brian, Yousefzadeh, Matthew, Tchkonia, Tamar et al. · 2021 · The Journals of Gerontology: Series A
- Epigenetics of Aging and Aging-Associated DiseasesDominik Saul, Robyn Laura Kosinsky · 2021 · International Journal of Molecular Sciences
- Aging Hallmarks: The Benefits of Physical ExerciseRebelo-Marques, Alexandre, De Sousa Lages, Adriana, Andrade, Renato, Ribeiro, Carlos Fontes, Mota-Pinto, Anabela, Carrilho, Francisco, Espregueira-Mendes, João · 2018 · Frontiers in Endocrinology
- Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast AgingMarion Claudia Salzer, Atefeh Lafzi, Antonio Berenguer, Catrin Youssif, Andrés Castellanos‐Martín, Guiomar Solanas, Francisca Oliveira Peixoto, Camille Stephan‐Otto Attolini, Neus Prats, Mònica Aguilera et al. · 2018 · Cell
- Basic Biology of Oxidative Stress and the Cardiovascular SystemMichael N. Sack, Frej Fyhrquist, Outi J. Saijonmaa, Valentín Fuster, Jason Ciril Kovacic · 2017 · Journal of the American College of Cardiology
- Targeting memory T cell metabolism to improve immunityMauro Corrado, Erika L. Pearce · 2022 · Journal of Clinical Investigation
- The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and DiseaseSchiller, Herbert B., Montoro, Daniel T., Simon, Lukas M., Rawlins, Emma L., Meyer, Kerstin B., Strunz, Maximilian, Vieira Braga, Felipe A., Timens, Wim, Koppelman, Gerard H., Budinger, G. R. Scott et al. · 2019 · American Journal of Respiratory Cell and Molecular Biology
- The African Turquoise Killifish Genome Provides Insights into Evolution and Genetic Architecture of LifespanDario Riccardo Valenzano, Bérénice Anath Benayoun, Param Priya Singh, Elisa Zhang, Paul D. Etter, Chi‐Kuo Hu, Mathieu Clément‐Ziza, David Willemsen, Rongfeng Cui, Itamar Harel et al. · 2015 · Cell
- Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunctionAmor, Corina, Fernández-Maestre, Inés, Chowdhury, Saria, Ho, Yu-Jui, Nadella, Sandeep, Graham, Courtenay, Carrasco, Sebastian E., Nnuji-John, Emmanuella, Feucht, Judith, Hinterleitner, Clemens et al. · 2024 · Nature Aging
- Reconsidering the Role of Mitochondria in AgingGonzalez-Freire, Marta, de Cabo, Rafael, Bernier, Michel, Sollott, Steven J., Fabbri, Elisa, Navas, Placido, Ferrucci, Luigi · 2015 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
- Classical and Nonclassical Intercellular Communication in Senescence and AgeingJuan Fafián‐Labora, Ana O’Loghlen · 2020 · Trends in Cell Biology
- Plant-Derived Bioactives and Oxidative Stress-Related Disorders: A Key Trend towards Healthy Aging and Longevity PromotionBahare Salehi, Elena Azzini, Paolo Zucca, Elena Maria Varoni, Nanjangud V. Anil Kumar, Luciana Dini, Elisa Panzarini, Jovana Rajković, Patrick Valère Tsouh Fokou, Ilaria Peluso et al. · 2020 · Applied Sciences
- A proposed panel of biomarkers of healthy ageingJosé Lara, Rachel Cooper, Jack Nissan, Annie T. Ginty, Kay‐Tee Khaw, Ian J. Deary, Janet M. Lord, Diana J. Kuh, John Cummings Mathers · 2015 · BMC Medicine
- PRKN-regulated mitophagy and cellular senescence during COPD pathogenesisJun Araya, Kazuya Tsubouchi, Nahoko Sato, Saburo Ito, Shunsuke Minagawa, Hiromichi Hara, Yusuke Hosaka, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota et al. · 2018 · Autophagy
- Sarcopenia and Muscle Aging: A Brief OverviewTam Dao, Alex E. Green, Yun-A Kim, Sung‐Jin Bae, Ki‐Tae Ha, Karim Gariani, Mi-ra Lee, Keir J. Menzies, Dongryeol Ryu · 2020 · Endocrinology and Metabolism
- Advances and Utility of the Human Plasma ProteomeEric W. Deutsch, Gilbert S. Omenn, Zhi Sun, Michal Maes, Maria Pernemalm, Krishnan K. Palaniappan, Natasha Letunica, Yves Vandenbrouck, Virginie Brun, Sheng‐ce Tao et al. · 2021 · Journal of Proteome Research
- Ageing: from inflammation to cancerLeonardi, Giulia C., Accardi, Giulia, Monastero, Roberto, Nicoletti, Ferdinando, Libra, Massimo · 2018 · Immunity & Ageing
- Gut microbiota drives age-related oxidative stress and mitochondrial damage in microglia via the metabolite N6-carboxymethyllysineMossad, Omar, Batut, Bérénice, Yilmaz, Bahtiyar, Dokalis, Nikolaos, Mezö, Charlotte, Nent, Elisa, Nabavi, Lara Susann, Mayer, Melanie, Maron, Feres José Mocayar, Buescher, Joerg M. et al. · 2022 · Nature Neuroscience
- Ageing exacerbates ribosome pausing to disrupt cotranslational proteostasisKevin C. Stein, Fabián Morales-Polanco, Joris CJ van der Lienden, T. Kelly Rainbolt, Judith Frydman · 2022 · Nature
- Calorie Restriction and Aging in HumansFlanagan, Emily W., Most, Jasper, Mey, Jacob T., Redman, Leanne M. · 2020 · Annual Review of Nutrition
- Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolismHahn, Oliver, Grönke, Sebastian, Stubbs, Thomas M., Ficz, Gabriella, Hendrich, Oliver, Krueger, Felix, Andrews, Simon, Zhang, Qifeng, Wakelam, Michael J., Beyer, Andreas et al. · 2017 · Genome Biology
- MARK-AGE biomarkers of ageingAlexander Bürkle, María Moreno‐Villanueva, Jürgen Bernhard, Marı́a A. Blasco, Gerben C. M. Zondag, Jan H.J. Hoeijmakers, Olivier Toussaint, Beatrix Grubeck‐Loebenstein, Eugenio Mocchegiani, Sebastiano Collino et al. · 2015 · Mechanisms of Ageing and Development
- TERT promoter mutations in cancer developmentHeidenreich, Barbara, Rachakonda, P Sivaramakrishna, Hemminki, Kari, Kumar, Rajiv · 2014 · Current Opinion in Genetics & Development
- Effects of Acute and Chronic Exercise on Immunological Parameters in the Elderly Aged: Can Physical Activity Counteract the Effects of Aging?Maha Sellami, Maha Gasmi, Joshua Denham, Lawrence D. Hayes, Dan Stratton, Johnny Padulo, Nicola Luigi Bragazzi · 2018 · Frontiers in Immunology
- New Therapeutic Targets in Idiopathic Pulmonary Fibrosis. Aiming to Rein in Runaway Wound-Healing ResponsesNeil Ahluwalia, Barry S. Shea, Andrew Martin Tager · 2014 · American Journal of Respiratory and Critical Care Medicine
- Protein Posttranslational Modifications: Roles in Aging and Age‐Related DiseaseAna L. Santos, Ariel B. Lindner · 2017 · Oxidative Medicine and Cellular Longevity
- AGE RELATED CHANGES IN BONE MARROW MESENCHYMAL STROMAL CELLS: A POTENTIAL IMPACT ON OSTEOPOROSIS AND OSTEOARTHRITIS DEVELOPMENTPayal Ganguly, Jehan J. El‐Jawhari, Peter Vasilios Giannoudis, Agata N. Burska, Frédérique Ponchel, Elena Jones · 2017 · Cell Transplantation
- Cellular senescence at the crossroads of inflammation and Alzheimer's diseaseGuerrero, Ana, De Strooper, Bart, Arancibia-Cárcamo, I. Lorena · 2021 · Trends in Neurosciences
- Mitochondria in the spotlight of aging and idiopathic pulmonary fibrosisAna Lucia Mora, Marta Bueno, Mauricio M. Rojas · 2017 · Journal of Clinical Investigation
- The Role of Oxidative Stress and Natural Antioxidants in Ovarian AgingLiuqing Yang, Yun Chen, Yan Liu, Yu Xing, Chenyun Miao, Ying Zhao, Xiangwei Chang, Qin Zhang · 2021 · Frontiers in Pharmacology
- The leading role of epithelial cells in the pathogenesis of idiopathic pulmonary fibrosisMoisés Selman, Annie Pardo · 2019 · Cellular Signalling
- Ageing affects DNA methylation drift and transcriptional cell-to-cell variability in mouse muscle stem cellsHernando-Herraez, Irene, Evano, Brendan, Stubbs, Thomas, Commere, Pierre-Henri, Jan Bonder, Marc, Clark, Stephen, Andrews, Simon, Tajbakhsh, Shahragim, Reik, Wolf · 2019 · Nature Communications
- Senescence and Cancer: A Review of Clinical Implications of Senescence and SenotherapiesWyld, Lynda, Bellantuono, Ilaria, Tchkonia, Tamara, Morgan, Jenna, Turner, Olivia, Foss, Fiona, George, Jayan, Danson, Sarah, Kirkland, James L. · 2020 · Cancers
- Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-κBBo Yu, Jia Chang, Yunsong Liu, Jiong Li, Kareena Kevork, Khalid Al‐Hezaimi, Dana T. Graves, No-Hee Park, Cun‐Yu Wang · 2014 · Nature Medicine
- Introduction to Population BiologyDick Neal · 2003 · Cambridge University Press eBooks
- Mitochondria in the signaling pathways that control longevity and health spanMansour Akbari, Thomas B. L. Kirkwood, Vilhelm A. Bohr · 2019 · Ageing Research Reviews
- Brain Endothelial Cells Are Exquisite Sensors of Age-Related Circulatory CuesChen, Michelle B., Yang, Andrew C., Yousef, Hanadie, Lee, Davis, Chen, Winnie, Schaum, Nicholas, Lehallier, Benoit, Quake, Stephen R., Wyss-Coray, Tony · 2020 · Cell Reports
- Review: Astrocytes in Alzheimer's disease and other age‐associated dementias: a supporting player with a central roleGarwood, C. J., Ratcliffe, L. E., Simpson, J. E., Heath, P. R., Ince, P. G., Wharton, S. B. · 2017 · Neuropathology and Applied Neurobiology
- ATP-Dependent Lon Protease Controls Tumor Bioenergetics by Reprogramming Mitochondrial ActivityQuirós, Pedro M., Español, Yaiza, Acín-Pérez, Rebeca, Rodríguez, Francisco, Bárcena, Clea, Watanabe, Kenta, Calvo, Enrique, Loureiro, Marta, Fernández-García, M. Soledad, Fueyo, Antonio et al. · 2014 · Cell Reports
- Polyglutamine-Expanded Huntingtin Exacerbates Age-Related Disruption of Nuclear Integrity and Nucleocytoplasmic TransportFátima Gasset-Rosa, Carlos Chillón-Marinas, Alexander Goginashvili, Ranjit Singh Atwal, Jonathan W. Artates, Ricardos Tabet, Vanessa C. Wheeler, Anne G. Bang, Don W. Cleveland, Clotilde Lagier‐Tourenne · 2017 · Neuron
- FOXOs attenuate bone formation by suppressing Wnt signalingSrividhya V. Iyer, Elena Ambrogini, Shoshana M. Bartell, Han Li, Paula K. Roberson, Rafael de Cabo, Robert L. Jilka, Robert S. Weinstein, Charles A. O’Brien, Stavros C. Manolagas et al. · 2013 · Journal of Clinical Investigation
- Inflammaging and the SkinSuzanne M. Pilkington, Silvia Bulfone‐Paus, Christopher E.M. Griffiths, Rachel E. B. Watson · 2021 · Journal of Investigative Dermatology
- Inflammaging: Implications in SarcopeniaEduardo Antuña, Cristina Cachán-Vega, Juan Carlos Bermejo-Millo, Yaiza Potes, Beatriz Caballero, Ignacio Vega‐Naredo, Ana M. Coto‐Montes, Claudia García-González · 2022 · International Journal of Molecular Sciences
- Senescent cells: SASPected drivers of age-related pathologiesOvadya, Yossi, Krizhanovsky, Valery · 2014 · Biogerontology
- A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived VertebrateHarel, Itamar, Benayoun, Bérénice A., Machado, Ben, Singh, Param Priya, Hu, Chi-Kuo, Pech, Matthew F., Valenzano, Dario Riccardo, Zhang, Elisa, Sharp, Sabrina C., Artandi, Steven E. et al. · 2015 · Cell
- Do DNA Double-Strand Breaks Drive Aging?White, Ryan R., Vijg, Jan · 2016 · Molecular Cell
- Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to StressGuiomar Solanas, Francisca Oliveira Peixoto, Eusebio Perdiguero, Mercè Jardí, Vanessa Ruiz‐Bonilla, Debayan Datta, Aikaterini Symeonidi, Andrés Castellanos‐Martín, Patrick-Simon Welz, Javier Manuel Caballero et al. · 2017 · Cell
- Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase SeparationChen Wang, Yongjia Duan, Gang Duan, Qiangqiang Wang, Kai Zhang, Xue Deng, Beituo Qian, Jinge Gu, Zhiwei Ma, Shuang Zhang et al. · 2020 · Molecular Cell
- The Critical Need to Promote Research of Aging and Aging-related Diseases to Improve Health and Longevity of the Elderly PopulationKunlin Jin · 2014 · Aging and Disease
- Glial Development: The Crossroads of Regeneration and Repair in the CNSVittorio Gallo, Benjamin Deneen · 2014 · Neuron
- Diet and Skin Aging—From the Perspective of Food NutritionCao, Changwei, Xiao, Zhichao, Wu, Yinglong, Ge, Changrong · 2020 · Nutrients
- Serum copper to zinc ratio: Relationship with aging and health statusMarco Malavolta, Francesco Piacenza, Andrea Basso, Robertina Giacconi, Laura Costarelli, Eugenio Mocchegiani · 2015 · Mechanisms of Ageing and Development
- Age-Associated Mitochondrial Dysfunction Accelerates AtherogenesisDaniel J. Tyrrell, Muriel G. Blin, Jianrui Song, Sherri Chan Wood, Min Zhang, Daniel Andrew Beard, Daniel R. Goldstein · 2019 · Circulation Research
- Targeting immune dysfunction in agingSimone Borgoni, Kseniya S. Kudryashova, Ksenia Burka, João Pedro de Magalhães · 2021 · Ageing Research Reviews
- Blue light-induced oxidative stress in live skinYuya Nakashima, Shigeo Ohta, Alexander Martin Wolf · 2017 · Free Radical Biology and Medicine
- The Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheromaSarah J. Zaman, Jason H. Wasfy, Vikas Kapil, Boback Ziaeian, William Anthony Parsonage, Sira Sriswasdi, Tim Chico, Davide Capodanno, Róisín Colleran, Nadia R. Sutton et al. · 2025 · The Lancet
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- Accelerated Accumulation of Multimorbidity After Bilateral Oophorectomy: A Population-Based Cohort StudyWalter A. Rocca, Liliana Gazzuola-Rocca, Carin Y. Smith, Brandon R. Grossardt, Stephanie S. Faubion, Lynne T. Shuster, James L. Kirkland, Elizabeth A. Stewart, Virginia M. Miller · 2016 · Mayo Clinic Proceedings
- Immunosenescence Study of T Cells: A Systematic ReviewIvón Johanna Rodríguez, Nicolás Lalinde-Ruiz, Manuela Llano León, Laura Camila Martínez-Enriquez, María del Pilar Montilla Velásquez, Juan Pablo Ortiz Aguirre, Oscar Mauricio Rodríguez Bohórquez, Esteban Alejandro Velandia Vargas, Edgar Debray Hernández-Álvarez, Carlos Parra-López · 2021 · Frontiers in Immunology
- Immunosenescence, aging and successful agingYunan Wang, Dong Chen, Yudian Han, Zhifeng Gu, Chi Chin Sun · 2022 · Frontiers in Immunology
- Autophagy and aging: Maintaining the proteome through exercise and caloric restrictionKurt A. Escobar, Nathan H. Cole, Christine M. Mermier, Trisha A. VanDusseldorp · 2018 · Aging Cell
- Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and womenGaran Jones, Katerina Trajanoska, Adam J. Santanasto, Najada Stringa, Chia‐Ling Kuo, Janice L. Atkins, Joshua Richard Lewis, ThuyVy Duong, Shengjun Hong, Mary Lou Biggs et al. · 2021 · Nature Communications
- The role of declining adaptive homeostasis in ageingLaura C.D. Pomatto, Kelvin J.A. Davies · 2017 · The Journal of Physiology
- Transcriptional and epigenetic decoding of the microglial aging processXiaoyu Li, Yuxin Li, Yuxiao Jin, Yuheng Zhang, Jingchuan Wu, Zhen Xu, Yubin Huang, Lin Cai, Shuai Gao, Taohui Liu et al. · 2023 · Nature Aging
- Underlying features of epigenetic aging clocks in vivo and in vitro.Liu, Zuyun, Leung, Diana, Thrush, Kyra, Zhao, Wei, Ratliff, Scott, Tanaka, Toshiko, Schmitz, Lauren L., Smith, Jennifer A., Ferrucci, Luigi, Levine, Morgan E. · 2020 · Aging Cell
- Accelerated biological aging in COVID-19 patientsXue Cao, Wenjuan Li, Ting Wang, Dongzhi Ran, Verónica Dávalos, Laura Planas‐Serra, Aurora Pujol, Manel Esteller, Xiaolin Wang, Huichuan Yu · 2022 · Nature Communications
- The Emergence of Geroscience as an Interdisciplinary Approach to the Enhancement of Health Span and Life SpanFelipe Sierra · 2016 · Cold Spring Harbor Perspectives in Medicine
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- Role of Age-Related Mitochondrial Dysfunction in SarcopeniaFerri, Evelyn, Marzetti, Emanuele, Calvani, Riccardo, Picca, Anna, Cesari, Matteo, Arosio, Beatrice · 2020 · International Journal of Molecular Sciences
- Stress Biology and Aging Mechanisms: Toward Understanding the Deep Connection Between Adaptation to Stress and LongevityEpel, E. S., Lithgow, G. J. · 2014 · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
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- Mitochondria, energy, and metabolism in neuronal health and diseaseDiogo Trigo, Catarina Avelar, Miguel Fernandes, Juliana Sá, Odete A. B. da Cruz e Silva · 2022 · FEBS Letters
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- Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell FunctionArda, H. Efsun, Li, Lingyu, Tsai, Jennifer, Torre, Eduardo A., Rosli, Yenny, Peiris, Heshan, Spitale, Robert C., Dai, Chunhua, Gu, Xueying, Qu, Kun et al. · 2016 · Cell Metabolism
- Long noncoding RNAs (lncRNAs) and the molecular hallmarks of agingIoannis Grammatikakis, Amaresh Chandra Panda, Kotb Abdelmohsen, Myriam Gorospe · 2014 · Aging
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- Mechanisms of Aging and the Preventive Effects of Resveratrol on Age-Related DiseasesIn Soo Pyo, Suyeon Yun, Ye Eun Yoon, Jung Won Choi, Sung‐Joon Lee · 2020 · Molecules
- Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan ExtensionZhou, Ben, Kreuzer, Johannes, Kumsta, Caroline, Wu, Lianfeng, Kamer, Kimberli J., Cedillo, Lucydalila, Zhang, Yuyao, Li, Sainan, Kacergis, Michael C., Webster, Christopher M. et al. · 2019 · Cell
- Impaired ribosome biogenesis: mechanisms and relevance to cancer and agingZsofia Turi, Matthew Lacey, Martin Mistrík, Pavel Moudrý · 2019 · Aging
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