Magnetic fluid hyperthermia: focus on superparamagnetic iron oxide nanoparticles
Open accessAbstract
Due to their unique magnetic properties, excellent biocompatibility as well as multi-purpose biomedical potential (e.g., applications in cancer therapy and general drug delivery), superparamagnetic iron oxide nanoparticles (SPIONs) are attracting increasing attention in both pharmaceutical and industrial communities. The precise control of the physiochemical properties of these magnetic systems is crucial for hyperthermia applications, as the induced heat is highly dependent on these properties. In this review, the limitations and recent advances in the development of superparamagnetic iron oxide nanoparticles for hyperthermia are presented.
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Guardia et al. observed a linear SAR dependence as a function of frequency at a fixed amplitude and a quadratic SAR dependence as a function of amplitude at a fixed frequency for water-soluble iron oxide nanocubes.
“Interestingly, Guardia et al. observed a linear SAR dependence as a function of frequency (at a fixed amplitude) and a quadratic SAR dependence as a function of amplitude (at a fixed frequency) for water-soluble iron oxide nanocubes [15, 115].”
From Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications (2019) · cites this paper as [15]
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- Authors
- Laurent, S., Dutz, S., Häfeli, U. O., & Mahmoudi, M.
- Affiliations
- University of Mons (BE)
- University of British Columbia (CA)
- Pasteur Institute of Iran (IR)
- Corresponding author
- Mahmoudi, Morteza
- Venue
- Advances in Colloid and Interface Science
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 166
- Issue
- 1-2
- Pages
- 8-23
- ISSN
- 0001-8686 (ISSN-L)
- OpenAlex
- W2014777534
- Cited by
- 1,326
- References
- 235
- Citations by year
- 2026: 37 · 2025: 56 · 2024: 45 · 2023: 70 · 2022: 96 · 2021: 113 · 2020: 113 · 2019: 112 · 2018: 94 · 2017: 119 · 2016: 124 · 2015: 106 · 2014: 94 · 2013: 76 · 2012: 59
- FWCI
- 6.14
- Type
- journal article
- Language
- en
- Open access
- green
- orbi.umons.ac.be
- Licence
- Locations
- Advances in Colloid and Interface Science (publishedVersion)
- PubMed (publishedVersion)
- ORBi UMONS (submittedVersion, other-oa)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Characterization and Applications of Magnetic Nanoparticles
- Physical Sciences › Materials Science › Materials Chemistry › Magnetic Properties and Synthesis of Ferrites
- Physical Sciences › Materials Science › Biomaterials › Nanoparticle-Based Drug Delivery
- Keywords
- magnetic hyperthermia, superparamagnetic iron oxide nanoparticles, magnetic nanoparticles, cancer therapy, drug delivery, biocompatibility, physicochemical properties, heat generation, nanoparticle synthesis
- MeSH terms
- Animals, Humans, Hyperthermia, Induced, Magnetics, Materials Testing, Temperature, Drug Delivery Systems, Chemical Phenomena, Magnetite Nanoparticles
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