Neuromodulation by oxytocin and vasopressin in the central nervous system as a basis for their rapid behavioral effects
Open accessAbstract
The last several years have seen an increasing number of studies that describe effects of oxytocin and vasopressin on the behavior of animals or humans. Studies in humans have reported behavioral changes and, through fMRI, effects on brain function. These studies are paralleled by a large number of reports, mostly in rodents, that have also demonstrated neuromodulatory effects by oxytocin and vasopressin at the circuit level in specific brain regions. It is the scope of this review to give a summary of the most recent neuromodulatory findings in rodents with the aim of providing a potential neurophysiological basis for their behavioral effects. At the same time, these findings may point to promising areas for further translational research towards human applications.
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Flagged first, then by citations
Research works printed but not linked: 3
- [14]14. **Excellent review about the role of both neuropeptides in social behavior.
- [9]9. *Interesting review on social functions providing many examples across different species, with a focus on aggression, affiliation, bonding, social stress, and parental behavior. It discusses recent studies that demonstrate a diversity of sex-specific contributions of VP-OT cell groups to gregariousness and pair bonding.
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- Authors
- Stoop, R.
- Affiliations
- Centre Hospitalier Universitaire Vaudois (CH)
- Corresponding author
- Stoop, Ron
- ORCID
- Stoop, Ron
- Venue
- Current Opinion in Neurobiology
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 29
- Pages
- 187-193
- ISSN
- 0959-4388 (ISSN-L)
- OpenAlex
- W2014187448
- Cited by
- 84
- References
- 51
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 4 · 2023: 8 · 2022: 6 · 2021: 3 · 2020: 9 · 2019: 7 · 2018: 7 · 2017: 13 · 2016: 15 · 2015: 7
- FWCI
- 1.67
- Type
- journal article
- Language
- en
- Open access
- green
- serval.unil.ch
- Licence
- Locations
- Current Opinion in Neurobiology (publishedVersion)
- PubMed (publishedVersion)
- SERVAL (Université de Lausanne) (acceptedVersion, other-oa)
- IRIS (submittedVersion)
- Funders
- Swiss National Science Foundation (31003A_138526)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuropeptides and Animal Physiology
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Keywords
- oxytocin, vasopressin, neuromodulation, central nervous system, brain circuits, rodent models, translational research
- MeSH terms
- Animals, Behavior, Central Nervous System, Humans, Oxytocin, Vasopressins, Neurotransmitter Agents
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