Hypothalamic and other connections with dorsal CA2 area of the mouse hippocampus
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The CA2 area is an important, although relatively unexplored, component of the hippocampus. We used various tracers to provide a comprehensive analysis of CA2 connections in C57BL/6J mice. Using various adeno-associated viruses that express fluorescent proteins, we found a vasopressinergic projection from the paraventricular nuclei of the hypothalamus (PVN) to the CA2 as well as a projection from pyramidal neurons of the CA2 to the supramammillary nuclei. These projections were confirmed by retrograde tracing. As expected, we observed CA2 afferent projections from neurons in ipsilateral entorhinal cortical layer II as well as from bilateral dorsal CA2 and CA3 using retrograde tracers. Additionally, we saw CA2 neuronal input from bilateral medial septal nuclei, vertical and horizontal limbs of the nucleus of diagonal band of Broca, supramammillary nuclei (SUM), and median raphe nucleus. Dorsal CA2 injections of adeno-associated virus expressing green fluorescent protein revealed axonal projections primarily to dorsal CA1, CA2, and CA3 bilaterally. No projection was detected to the entorhinal cortex from the dorsal CA2. These results are consistent with recent observations that the dorsal CA2 forms disynaptic connections with the entorhinal cortex to influence dynamic memory processing. Mouse dorsal CA2 neurons send bilateral projections to the medial and lateral septal nuclei, vertical and horizontal limbs of the diagonal band of Broca, and SUM. Novel connections from the PVN and to the SUM suggest important regulatory roles for CA2 in mediating social and emotional input for memory processing.
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Oxytocin and vasopressin-expressing cells in the paraventricular and supraoptic nuclei send projections to the hippocampus, with the highest fiber density seen in the CA2 region for vasopressin and CA2/CA3 regions for oxytocin projections.
“OXT and AVPexpressing cells in PVN and SON send projections to the hippocampus, with the highest fiber density seen in the CA2 region for AVP and CA2/CA3 regions for OXT projections (97-100).”
From Oxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities (2022) · cites this paper as [98]
The failure to observe vasopressinergic input to CA2 from the paraventricular nucleus may reflect an inability of the transsynaptic rabies tracing system to label peptidergic inputs.
“we failed to observe vasopressinergic input to CA2 from the paraventricular nucleus of the hypothalamus13, which may reflect an inability of the transsynaptic rabies tracing system to label peptidergic inputs15.”
From The hippocampal CA2 region is essential for social memory (2014) · cites this paper as [13]
The absence of observed CA2 output to the supramammillary nucleus suggests this output may represent an inhibitory projection from CA2, as only pyramidal neurons were labeled.
“We also did not observe CA2 output to the supramammillary nucleus13, suggesting this output may represent an inhibitory projection from CA2 as we selectively labeled PNs.”
From The hippocampal CA2 region is essential for social memory (2014) · cites this paper as [13]
The anatomical results generally support previous findings on CA2 connectivity.
“These anatomical results generally support previous13,14 findings.”
From The hippocampal CA2 region is essential for social memory (2014) · cites this paper as [13]
The large EPSPs previously evoked in CA2 pyramidal neurons by focal stimulation in CA1 stratum lacunosum may result from activation of entorhinal cortex layer II fibers that course through or near stratum lacunosum, rather than layer III axons.
“Our present results, combined with recent results13,14 suggest that these synaptic responses recorded in CA2 PNs may result from activation of LII fibers that course through or near SLM in CA1.”
From The hippocampal CA2 region is essential for social memory (2014) · cites this paper as [13]
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The mouse brain in stereotaxic coordinates
Konsman, J. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00088-x · Cited by 16,796 · see citing works
Genome-wide atlas of gene expression in the adult mouse brain
Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature · doi:10.1038/nature05453 · Cited by 5,572 · see citing works
Microstructure of a spatial map in the entorhinal cortex
Hafting, T., Fyhn, M., Molden, S., Moser, M.-B., & Moser, E. I. (2005) · Nature · doi:10.1038/nature03721 · Cited by 4,068 · see citing works
The three-dimensional organization of the hippocampal formation: A review of anatomical data
Amaral, D. G., & Witter, M. P. (1989) · Neuroscience · doi:10.1016/0306-4522(89)90424-7 · Cited by 2,180 · see citing works
de Nó, R. L. (1934) · Cited by 1,974 · see citing works
Lantos, P. L. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.5.496 · Cited by 1,154 · see citing works
The connections of the septal region in the rat
Swanson, L. W., & Cowan, W. M. (1979) · The Journal of Comparative Neurology · doi:10.1002/cne.901860408 · Cited by 1,136 · see citing works
The anatomy of memory: an interactive overview of the parahippocampal–hippocampal network
van Strien, N. M., Cappaert, N. L. M., & Witter, M. P. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2614 · Cited by 1,041 · see citing works
Gong, S., Doughty, M., Harbaugh, C. R., Cummins, A., Hatten, M. E., Heintz, N., & Gerfen, C. R. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.2707-07.2007 · Cited by 977 · see citing works
Organization of intrahippocampal projections originating from CA3 pyramidal cells in the rat
Ishizuka, N., Weber, J., & Amaral, D. G. (1990) · The Journal of Comparative Neurology · doi:10.1002/cne.902950407 · Cited by 899 · see citing works
Cells of origin of entorhinal cortical afferents to the hippocampus and fascia dentata of the rat
Steward, O., & Scoville, S. A. (1976) · The Journal of Comparative Neurology · doi:10.1002/cne.901690306 · Cited by 837 · see citing works
The hippocampal CA3 network: An in vivo intracellular labeling study
Li, X. ‐., Somogyi, P., Ylinen, A., & Buzsáki, G. (1994) · The Journal of Comparative Neurology · doi:10.1002/cne.903390204 · Cited by 751 · see citing works
Hippocampal remapping and grid realignment in entorhinal cortex
Fyhn, M., Hafting, T., Treves, A., Moser, M.-B., & Moser, E. I. (2007) · Nature · doi:10.1038/nature05601 · Cited by 749 · see citing works
Kainic acid seizures in the rat
Sperk, G. (1994) · Progress in Neurobiology · doi:10.1016/0301-0082(94)90019-1 · Cited by 688 · see citing works
Major Dissociation Between Medial and Lateral Entorhinal Input to Dorsal Hippocampus
Hargreaves, E. L., Rao, G., Lee, I., & Knierim, J. J. (2005) · Science · doi:10.1126/science.1110449 · Cited by 685 · see citing works
Hippocampal Efferents Reach Widespread Areas of Cerebral Cortex and Amygdala in the Rhesus Monkey
Rosene, D. L., & Hoesen, G. W. V. (1977) · Science · doi:10.1126/science.410102 · Cited by 678 · see citing works
Sarter, M., Hasselmo, M. E., Bruno, J. P., & Givens, B. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.08.006 · Cited by 667 · see citing works
Simerly, R. B., & Swanson, L. W. (1988) · The Journal of Comparative Neurology · doi:10.1002/cne.902700205 · Cited by 592 · see citing works
Limbic Regulation of Hypothalamo‐Pituitary‐Adrenocortical Function during Acute and Chronic Stress
Jankord, R., & Herman, J. P. (2008) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1410.012 · Cited by 578 · see citing works
CNS Distribution of Members of the Two-Pore-Domain (KCNK) Potassium Channel Family
Talley, E. M., Solórzano, G., Lei, Q., Kim, D., & Bayliss, D. A. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-19-07491.2001 · Cited by 573 · see citing works
Beck, C., & Fibiger, H. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-01-00709.1995 · Cited by 547 · see citing works
The vasopressinergic innervation of the brain in normal and castrated rats
DeVries, G. J., Buijs, R. M., van Leeuwen, F. W., Caffé, A. R., & Swaab, D. F. (1985) · Journal of Comparative Neurology · doi:10.1002/cne.902330206 · Cited by 522 · see citing works
A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
Benes, F. M., Kwok, E. W., Vincent, S. L., & Todtenkopf, M. S. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00138-3 · Cited by 470 · see citing works
Meibach, R. C., & Siegel, A. (1977) · Brain Research · doi:10.1016/0006-8993(77)90088-9 · Cited by 438 · see citing works
Functional neuroanatomy of the parahippocampal region: The lateral and medial entorhinal areas
Kerr, K. M., Agster, K. L., Furtak, S. C., & Burwell, R. D. (2007) · Hippocampus · doi:10.1002/hipo.20315 · Cited by 433 · see citing works
Linking context with reward: a functional circuit from hippocampal CA3 to ventral tegmental area
Luo, A. H., Tahsili-Fahadan, P., Wise, R. A., Lupica, C. R., & Aston-Jones, G. (2011) · Science · doi:10.1126/science.1204622 · Cited by 425 · see citing works
Dysregulation of the fibroblast growth factor system in major depression
Evans, S. J., Choudary, P. V., Neal, C. R., Li, J. Z., Vawter, M. P., Tomita, H., Lopez, J. F., Thompson, R. C., Meng, F., Stead, J. D., et al. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0406788101 · Cited by 424 · see citing works
Epilepsy and Neuron Loss in the Hippocampus
Dam, A. M. (1980) · Epilepsia · doi:10.1111/j.1528-1157.1980.tb04315.x · Cited by 413 · see citing works
Genomic anatomy of the hippocampus
Thompson, C. L., Pathak, S. D., Jeromin, A., Ng, L. L., MacPherson, C. R., Mortrud, M. T., Cusick, A., Riley, Z. L., Sunkin, S. M., Bernard, A., et al. (2008) · Neuron · doi:10.1016/j.neuron.2008.12.008 · Cited by 403 · see citing works
Vasopressin V1b receptor knockout reduces aggressive behavior in male mice
Wersinger, S. R., Ginns, E. I., O'Carroll, A.-M., Lolait, S. J., & Young III, W. S. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001195 · Cited by 397 · see citing works
Memory Representation within the Parahippocampal Region
Young, B. J., Otto, T., Fox, G. D., & Eichenbaum, H. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-13-05183.1997 · Cited by 363 · see citing works
The axonal projection patterns of the mitral and tufted cells of the olfactory bulb in the rat
Haberly, L. B., & Price, J. L. (1977) · Brain Research · doi:10.1016/0006-8993(77)90978-7 · Cited by 342 · see citing works
Strong CA2 Pyramidal Neuron Synapses Define a Powerful Disynaptic Cortico-Hippocampal Loop
Chevaleyre, V., & Siegelbaum, S. A. (2010) · Neuron · doi:10.1016/j.neuron.2010.04.013 · Cited by 324 · see citing works
PHA-L analysis of projections from the supramammillary nucleus in the rat
Vertes, R. P. (1992) · Journal of Comparative Neurology · doi:10.1002/cne.903260408 · Cited by 299 · cited 1× · see citing works
“We confirmed earlier findings from tracer studies that SUM innervates the dorsal CA2 (Haglund et al., 1984; Vertes, 1992; Magloczky et al., 1994; Ochiishi et al., 1999; Kiss et al., 2000).”
ResultLein, E. S., Zhao, X., & Gage, F. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4710-03.2004 · Cited by 270 · see citing works
Haglund, L., Swanson, L. W., & Köhler, C. (1984) · The Journal of Comparative Neurology · doi:10.1002/cne.902290204 · Cited by 264 · see citing works
Restoring theta‐like rhythmicity in rats restores initial learning in the Morris water maze
McNaughton, N., Ruan, M., & Woodnorth, M. (2006) · Hippocampus · doi:10.1002/hipo.20235 · Cited by 255 · see citing works
Klein, R. L., Meyer, E. M., Peel, A. L., Zolotukhin, S., Meyers, C., Muzyczka, N., & King, M. A. (1998) · Experimental Neurology · doi:10.1006/exnr.1997.6736 · Cited by 252 · see citing works
Kocsis, B., & Vertes, R. P. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-11-07040.1994 · Cited by 242 · see citing works
Supramammillary cell firing and hippocampal rhythmical slow activity
Kirk, I. J., & McNaughton, N. (1991) · Neuroreport · doi:10.1097/00001756-199111000-00023 · Cited by 241 · see citing works
The cholinergic system and hippocampal plasticity
Drever, B. D., Riedel, G., & Platt, B. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2010.11.037 · Cited by 240 · see citing works
Young, W. S., Li, J., Wersinger, S. R., & Palkovits, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.040 · Cited by 222 · see citing works
Chamberlin, N. L., Du, B., de Lacalle, S., & Saper, C. B. (1998) · Brain Research · doi:10.1016/s0006-8993(98)00169-3 · Cited by 221 · see citing works
Tamamaki, N., & Nojyo, Y. (1993) · Hippocampus · doi:10.1002/hipo.450030408 · Cited by 216 · see citing works
Nyakas, C. J., Luiten, P. G. M., Spencer, D. G., & Traber, J. (1987) · Brain Research Bulletin · doi:10.1016/0361-9230(87)90117-1 · Cited by 213 · see citing works
Stranahan, A. M., & Mattson, M. P. (2010) · Neural Plasticity · doi:10.1155/2010/108190 · Cited by 198 · cited 1× · see citing works
“…receives input from postrhinal cortex, which transmits primarily afferents from visual and parietal cortex (Kerr et al., 2007), whereas LEC receives direct olfactory input (Haberly and Price, 1977; Stranahan and Mattson, 2010) and encodes socially relevant odor information (Petrulis et al., 2005).”
BackgroundTranscriptional profiling reveals strict boundaries between hippocampal subregions
Zhao, X., Lein, E. S., He, A., Smith, S. C., Aston, C., & Gage, F. H. (2001) · The Journal of Comparative Neurology · doi:10.1002/cne.1406 · Cited by 196 · see citing works
Zhu, X. O., Brown, M. W., & Aggleton, J. P. (1995) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1995.tb00679.x · Cited by 194 · see citing works
Köhler, C., Chan‐Palay, V., & Steinbusch, H. W. M. (1982) · The Journal of Comparative Neurology · doi:10.1002/cne.902090109 · Cited by 188 · see citing works
Synaptic Plasticity (and the Lack Thereof) in Hippocampal CA2 Neurons
Zhao, M., Choi, Y., Obrietan, K. H., & Dudek, S. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4094-07.2007 · Cited by 181 · see citing works
Hippocampal FGF-2 and FGFR1 mRNA expression in major depression, schizophrenia and bipolar disorder
Gaughran, F., Payne, J., Sedgwick, P. M., Cotter, D., & Berry, M. (2006) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2006.04.008 · Cited by 178 · see citing works
de Olmos, J. S., Beltramino, C. A., & Alheid, G. F. (2004) · Elsevier eBooks · doi:10.1016/b978-012547638-6/50020-1 · Cited by 160 · see citing works
Lein, E. S., Callaway, E. M., Albright, T. D., & Gage, F. H. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20426 · Cited by 158 · see citing works
Maglóczky, Z., Acsády, L., & Freund, T. F. (1994) · Hippocampus · doi:10.1002/hipo.450040316 · Cited by 158 · see citing works
Wyss, J. M., Swanson, L. W., & Cowan, W. M. (1979) · Anatomy and Embryology · doi:10.1007/bf00300012 · Cited by 148 · see citing works
Vasopressin 1b Receptor Knock-Out Impairs Memory for Temporal Order
DeVito, L. M., Konigsberg, R., Lykken, C., Sauvage, M., Young, W. S., & Eichenbaum, H. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5488-08.2009 · Cited by 147 · see citing works
Self-citationTargeted Retrograde Gene Delivery for Neuronal Protection
Kaspar, B. K., Erickson, D. A., Schaffer, D. V., Hinh, L., Gage, F. H., & Peterson, D. A. (2002) · Molecular Therapy · doi:10.1006/mthe.2001.0520 · Cited by 147 · see citing works
Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectors
Alisky, J. M., Hughes, S. M., Sauter, S. L., Jolly, D. J., Dubensky, T. W., Staber, P. D., Chiorini, J. A., & Davidson, B. L. (2000) · Neuroreport · doi:10.1097/00001756-200008210-00013 · Cited by 143 · see citing works
Behzadi, G., Kalén, P., Parvopassu, F., & Wiklund, L. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90194-9 · Cited by 140 · see citing works
Morin, L. P., & Meyer-Bernstein, E. L. (1999) · Neuroscience · doi:10.1016/s0306-4522(98)00585-5 · Cited by 136 · see citing works
Vasopressin innervation of the mouse ( <i>Mus musculus</i> ) brain and spinal cord
Rood, B. D., & De Vries, G. J. (2011) · Journal of Comparative Neurology · doi:10.1002/cne.22635 · Cited by 134 · see citing works
Marcinkiewicz, M., Morcos, R., & Chrétien, M. (1989) · The Journal of Comparative Neurology · doi:10.1002/cne.902890103 · Cited by 134 · see citing works
Wersinger, S. R., Kelliher, K. R., Zufall, F., Lolait, S. J., O’Carroll, A., & Young, W. S. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.07.004 · Cited by 132 · see citing works
Wersinger, S. R., Caldwell, H. K., Christiansen, M., & Young, W. S. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00294.x · Cited by 130 · see citing works
Two types of corticopulvinar terminations: Round (type 2) and elongate (type 1)
Rockland, K. S. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960422)368:1 · Cited by 129 · see citing works
Smith, Y., Kieval, J. Z., Couceyro, P. R., & Kuhar, M. J. (1999) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19990517)407:4 · Cited by 122 · see citing works
Effects of median raphe nucleus lesions on hippocampal EEG in the freely moving rat
Maru, E., Takahashi, L. K., & Iwahara, S. (1979) · Brain Research · doi:10.1016/0006-8993(79)90351-2 · Cited by 118 · see citing works
Pan, W. X., & McNaughton, N. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02267.x · Cited by 112 · see citing works
Kiss, J., Csáki, Á., Bokor, H., Shanabrough, M., & Léránth, C. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00127-5 · Cited by 104 · see citing works
Perlis, R. H., Moorjani, P., Fagerness, J. A., Purcell, S., Trivedi, M. H., D, M. F. M., Rush, A. J., & Smoller, J. W. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.6 · Cited by 104 · see citing works
Segal, M., & Landis, S. C. (1974) · Brain Research · doi:10.1016/0006-8993(74)90603-9 · Cited by 101 · see citing works
Hippocampal CA3 and CA2 have distinct bilateral innervation patterns to CA1 in rodents
Shinohara, Y., Hosoya, A., Yahagi, K., Ferecskó, A. S., Yaguchi, K., Attila Gabor, S. I. K., Itakura, M., Takahashi, M., & Hirase, H. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.07993.x · Cited by 97 · see citing works
Zhang, L., & Hernández, V. S. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2012.10.010 · Cited by 96 · see citing works
Turner, C. A., Clinton, S. M., Thompson, R. C., Watson, S. J., & Akil, H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103732108 · Cited by 92 · see citing works
Wersinger, S. R., Temple, J. L., Caldwell, H. K., & Young, W. S. (2008) · Endocrinology · doi:10.1210/en.2007-1056 · Cited by 83 · see citing works
Ochiishi, T., Saitoh, Y., Yukawa, A., Saji, M., Ren, Y., Shirao, T., Miyamoto, H., Nakata, H., & Sekino, Y. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00179-7 · Cited by 83 · see citing works
Caffeine-induced synaptic potentiation in hippocampal CA2 neurons
Simons, S. B., Caruana, D. A., Zhao, M., & Dudek, S. M. (2011) · Nature Neuroscience · doi:10.1038/nn.2962 · Cited by 82 · see citing works
Intrinsic connections of the macaque monkey hippocampal formation: II. CA3 connections
Kondo, H., Lavenex, P., & Amaral, D. G. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22056 · Cited by 79 · see citing works
Honkaniemi, J., & Sharp, F. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00401.x · Cited by 77 · see citing works
Petrulis, A., Alvarez, P., & Eichenbaum, H. (2004) · Neuroscience · doi:10.1016/j.neuroscience.2004.09.001 · Cited by 75 · see citing works
Neuropeptides: Effects on paradoxical sleep and theta rhythm in rats
Urban, I. J. A., & de Wied, D. (1978) · Pharmacology Biochemistry and Behavior · doi:10.1016/0091-3057(78)90123-5 · Cited by 73 · see citing works
Delayed Signal Propagation via CA2 in Rat Hippocampal Slices Revealed by Optical Recording
Sekino, Y., Obata, K., Tanifuji, M., Mizuno, M., & Murayama, J. (1997) · Journal of Neurophysiology · doi:10.1152/jn.1997.78.3.1662 · Cited by 69 · see citing works
Parallel activation of field CA2 and dentate gyrus by synaptically elicited perforant path volleys
Bartesaghi, R., & GESSI, T. (2004) · Hippocampus · doi:10.1002/hipo.20011 · Cited by 59 · see citing works
Kinney, G. G., Kocsis, B., & Vertes, R. P. (1994) · Brain Research · doi:10.1016/0006-8993(94)91575-x · Cited by 58 · see citing works
Neuroanatomical study of afferent projections to the supramammillary nucleus of the rat
Hayakawa, T., Ito, H., & Zyo, K. (1993) · Anatomy and Embryology · doi:10.1007/bf00186247 · Cited by 57 · see citing works
Bartesaghi, R., Migliore, M., & Gessi, T. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.06.001 · Cited by 54 · see citing works
Electrophysiological characterization of CA2 pyramidal cells from epileptic humans
Williamson, A., & Spencer, D. D. (1994) · Hippocampus · doi:10.1002/hipo.450040213 · Cited by 52 · see citing works
Identification of retinal ganglion cells projecting to the lateral hypothalamic area of the rat
Leak, R. K., & Moore, R. Y. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00761-0 · Cited by 50 · see citing works
Kitchigina, V. F., Kudina, T. A., Kutyreva, E. V., & Vinogradova, O. S. (1999) · Neuroscience · doi:10.1016/s0306-4522(99)00258-4 · Cited by 47 · see citing works
Liou, Y., Chen, T., Tsai, S., Yu, Y. W. ‐., Cheng, C.-Y., & Hong, C. (2009) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e32832cbe61 · Cited by 46 · see citing works
Yoshida, K., & Oka, H. (1995) · Neuroscience Research · doi:10.1016/0168-0102(94)00852-7 · Cited by 43 · see citing works
Medina, L. M., & Abellán, A. (2011) · Elsevier eBooks · doi:10.1016/b978-0-12-369497-3.10007-x · Cited by 43 · see citing works
Ueta, Y., Dayanithi, G., & Fujihara, H. (2010) · Hormones and Behavior · doi:10.1016/j.yhbeh.2010.12.007 · Cited by 41 · see citing works
Ito, M., Shirao, T., Doya, K., & Sekino, Y. (2009) · Neuroscience Research · doi:10.1016/j.neures.2009.04.013 · Cited by 38 · see citing works
Urban, I. J. A. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61576-9 · Cited by 32 · see citing works
Saji, M., Kobayashi, S., Ohno, K., & Sekino, Y. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00081-6 · Cited by 20 · see citing works
Deng, C., & Rogers, L. J. (1999) · Journal of Neuroscience Methods · doi:10.1016/s0165-0270(99)00044-8 · Cited by 15 · see citing works
Miyata, S., Ishiyama, M., Shibata, M., Nakashima, T., & Kiyohara, T. (1998) · Neuroscience Research · doi:10.1016/s0168-0102(98)00045-5 · Cited by 12 · see citing works
Antidromic activation of a peptidergic pathway in the limbic system of the male rat
Albeck, D. S., Bullock, N., Marrs, K., Cooper, R. N., Smock, T., & Vries, G. J. D. (1993) · Brain Research · doi:10.1016/0006-8993(93)91587-i · Cited by 7 · see citing works
Kosiński, S. (1986) · PubMed · Cited by 2 · see citing works
Flagged first, then by citations
1 of the 101 references couldn’t be matched to a known paper.
Research works printed but not linked: 4
- Andersen P 2007 The hippocampus book Oxford; New York Oxford University Press 37 110
- De Olmos J Beltramino CA Alheid G 2004 Amygdala and extendedamygdala of the rat: a cytoarchitectonical, fibroarchitechtonical, and chemoarchitectonical survery Paxinos G The Rat Nervous System 3 New Yorl Elsevier 509 603
- Lein ES Callaway EM Albright TD Gage FH 2005b Redefining the boundaries of the hippocampal CA2 subfield in the mouse using gene expression and 3-dimensional reconstruction J Comp Neurol 485 1 1 10 15776443
- Meldrum BS Corsellis JAN 1984 Epilepsy Adams JH Corsellis JAN Duchen LW Greenfield’s Neuropathology 4 New York John Wiley & Sons 928 929
Cited by
Sorted by citations
The hippocampal CA2 region is essential for social memory
Hitti, F. L., & Siegelbaum, S. A. (2014) · Nature · doi:10.1038/nature13028 · Cited by 976 · see citing works
Cell type–specific genetic and optogenetic tools reveal hippocampal CA2 circuits
Kohara, K., Pignatelli, M., Rivest, A. J., Jung, H.-Y., Kitamura, T., Suh, J., Frank, D., Kajikawa, K., Mise, N., Obata, Y., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3614 · Cited by 528 · see citing works
Rediscovering area CA2: unique properties and functions
Dudek, S. M., Alexander, G. M., & Farris, S. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.22 · Cited by 329 · see citing works
Hippocampal CA2 activity patterns change over time to a larger extent than between spatial contexts
Mankin, E. A., Diehl, G. W., Sparks, F. T., Leutgeb, S., & Leutgeb, J. K. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.001 · Cited by 279 · see citing works
A distributed network for social cognition enriched for oxytocin receptors
Mitre, M., Marlin, B. J., Schiavo, J. K., Morina, E., Norden, S. E., Hackett, T. A., Aoki, C. J., Chao, M. V., & Froemke, R. C. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2409-15.2016 · Cited by 305 · see citing works
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression
Leroy, F., Park, J. M., Asok, A., Brann, D. H., Meira, T., Boyle, L. M., Buss, E. W., Kandel, E. R., & Siegelbaum, S. A. (2018) · Nature · doi:10.1038/s41586-018-0772-0 · Cited by 277 · see citing works
The Corticohippocampal Circuit, Synaptic Plasticity, and MemoryPreprint
Basu, J., & Siegelbaum, S. A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021733 · Cited by 244 · see citing works
Targeted activation of the hippocampal CA2 area strongly enhances social memory
Smith, A. S., Williams Avram, S. K., Cymerblit-Sabba, A., Song, J., & Young, W. S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.189 · Cited by 236 · see citing works
Self-citationBienkowski, M. S., Bowman, I., Song, M. Y., Gou, L., Ard, T., Cotter, K., Zhu, M., Benavidez, N. L., Yamashita, S., Abu-Jaber, J., et al. (2018) · Nature Neuroscience · doi:10.1038/s41593-018-0241-y · Cited by 224 · see citing works
A hippocampal network for spatial coding during immobility and sleep
Kay, K., Sosa, M., Chung, J. E., Karlsson, M. P., Larkin, M. C., & Frank, L. M. (2016) · Nature · doi:10.1038/nature17144 · Cited by 224 · see citing works
Role of Hippocampal CA2 Region in Triggering Sharp-Wave Ripples
Oliva, A., Fernández‐Ruiz, A., Buzsáki, G., & Berényi, A. (2016) · Neuron · doi:10.1016/j.neuron.2016.08.008 · Cited by 217 · see citing works
Ko, J. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00041 · Cited by 212 · see citing works
Pagani, J. H., Zhao, M., Cui, Z., Williams Avram, S. K., Caruana, D. A., Dudek, S. M., & Young, W. S. (2015) · Molecular Psychiatry · doi:10.1038/mp.2014.47 · Cited by 204 · see citing works
Self-citationSocial and novel contexts modify hippocampal CA2 representations of space
Alexander, G. M., Farris, S., Pirone, J. R., Zheng, C., Colgin, L. L., & Dudek, S. M. (2016) · Nature Communications · doi:10.1038/ncomms10300 · Cited by 191 · see citing works
Oxytocin, Vasopressin, and Social Behavior: From Neural Circuits to Clinical Opportunities
Rigney, N., de Vries, G. J., Petrulis, A., & Young, L. J. (2022) · Endocrinology · doi:10.1210/endocr/bqac111 · Cited by 191 · see citing works
Piskorowski, R. A., Nasrallah, K., Diamantopoulou, A., Mukai, J., Hassan, S. I., Siegelbaum, S. A., Gogos, J. A., & Chevaleyre, V. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.036 · Cited by 180 · see citing works
Evolution and development of interhemispheric connections in the vertebrate forebrain
Suárez, R., Gobius, I., & Richards, L. J. (2014) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2014.00497 · Cited by 175 · see citing works
Lin, Y.-T., Hsieh, T.-Y., Tsai, T.-C., Chen, C.-C., Huang, C.-C., & Hsu, K.-S. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.1896-17.2017 · Cited by 165 · see citing works
Lee, H., Wang, C., Deshmukh, S. S., & Knierim, J. J. (2015) · Neuron · doi:10.1016/j.neuron.2015.07.012 · Cited by 164 · see citing works
Oxytocin transforms firing mode of CA2 hippocampal neurons
Tirko, N. N., Eyring, K. W., Carcea, I., Mitre, M., Chao, M. V., Froemke, R. C., & Tsien, R. W. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.008 · Cited by 157 · see citing works
The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation
Lee, C. R., Chen, A., & Tye, K. M. (2021) · Cell · doi:10.1016/j.cell.2021.02.028 · Cited by 138 · see citing works
Oxytocin, vasopressin, and the motivational forces that drive social behaviors
Caldwell, H. K., & Albers, H. E. (2015) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2015_390 · Cited by 129 · see citing works
Adamowicz, D. H., Roy, S., Salmon, D. P., Galasko, D. R., Hansen, L. A., Masliah, E., & Gage, F. H. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.3047-16.2016 · Cited by 126 · see citing works
A role for CA3 in social recognition memory
Chiang, M.-C., Huang, A. J. Y., Wintzer, M. E., Ohshima, T., & McHugh, T. J. (2018) · Behavioural Brain Research · doi:10.1016/j.bbr.2018.01.019 · Cited by 129 · see citing works
Social Memory and the Role of the Hippocampal CA2 Region
Tzakis, N., & Holahan, M. R. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00233 · Cited by 122 · see citing works
Donegan, M. L., Stefanini, F., Meira, T., Gordon, J. A., Fusi, S., & Siegelbaum, S. A. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00720-5 · Cited by 114 · see citing works
Chronic Loss of CA2 Transmission Leads to Hippocampal Hyperexcitability
Boehringer, R., Polygalov, D., Huang, A. J. Y., Middleton, S. J., Robert, V., Wintzer, M. E., Piskorowski, R. A., Chevaleyre, V., & McHugh, T. J. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.014 · Cited by 105 · see citing works
The Hippocampal CA2 Ensemble Is Sensitive to Contextual Change
Wintzer, M. E., Boehringer, R., Polygalov, D., & McHugh, T. J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.2563-13.2014 · Cited by 98 · see citing works
Rodriguez, R. D., Suemoto, C. K., Molina, M., Nascimento, C. F., Leite, R. E. P., Ferretti‐Rebustini, R. E. D. L., Farfel, J. M., Heinsen, H., Nitríni, R., Uéda, K., et al. (2016) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlw034 · Cited by 94 · see citing works
Selective alterations of neurons and circuits related to early memory loss in Alzheimer’s disease
Llorens-Martı́n, M., Blázquez‐Llorca, L., Benavides‐Piccione, R., Rábano, A., Hernández, F., Ávila, J., & DeFelipe, J. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00038 · Cited by 94 · see citing works
Multimodal mapping and analysis of the cyto- and receptorarchitecture of the human hippocampus
Palomero‐Gallagher, N., Kedo, O., Mohlberg, H., Zilles, K., & Amunts, K. (2020) · Brain Structure and Function · doi:10.1007/s00429-019-02022-4 · Cited by 90 · see citing works
Price, M. P., Gong, H., Parsons, M. G., Kundert, J. R., Reznikov, L. R., Bernardinelli, L., Chaloner, K. M., Buchanan, G. F., Wemmie, J. A., Richerson, G. B., et al. (2013) · Genes Brain & Behavior · doi:10.1111/gbb.12108 · Cited by 90 · see citing works
Oxytocin and vasopressin in the rodent hippocampus
Cilz, N. I., Cymerblit‐Sabba, A., & Young, W. S. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12535 · Cited by 88 · see citing works
Stoop, R. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.09.012 · Cited by 84 · see citing works
Distribution of interneurons in the CA2 region of the rat hippocampus
Botcher, N. A., Falck, J. E., Thomson, A. M., & Mercer, A. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00104 · Cited by 82 · see citing works
Hippocampal Area CA2: An Overlooked but Promising Therapeutic Target
Chevaleyre, V., & Piskorowski, R. A. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.06.007 · Cited by 80 · see citing works
CA2: A Highly Connected Intrahippocampal Relay
Middleton, S. J., & McHugh, T. J. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080719-100343 · Cited by 79 · see citing works
Whitebirch, A. C., LaFrancois, J. J., Jain, S. S., Leary, P., Santoro, B., Siegelbaum, S. A., & Scharfman, H. E. (2022) · Neuron · doi:10.1016/j.neuron.2022.07.020 · Cited by 78 · see citing works
Sun, Q., Srinivas, K. V., Sotayo, A. O., & Siegelbaum, S. A. (2014) · eLife · doi:10.7554/elife.04551 · Cited by 79 · see citing works
Zhang, L., Hernández, V. S., Vázquez‐Juárez, E., Chay, F. K., & Barrio, R. A. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00013 · Cited by 76 · see citing works
CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing
Lehr, A. B., Kumar, A., Tetzlaff, C., Hafting, T., Fyhn, M., & Stöber, T. M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.03.020 · Cited by 74 · see citing works
ACE2 expression in rat brain: Implications for COVID-19 associated neurological manifestations
Hernández, V. S., Zetter, M. A., Guerra, E. C., Hernández‐Araiza, I., Karuzin, N., Hernández‐Pérez, O. R., Eiden, L. E., & Zhang, L. (2021) · Experimental Neurology · doi:10.1016/j.expneurol.2021.113837 · Cited by 76 · see citing works
Novel role for mineralocorticoid receptors in control of a neuronal phenotype
McCann, K. E., Lustberg, D. J., Shaughnessy, E. K., Carstens, K. E., Farris, S., Alexander, G. M., Radzicki, D., Zhao, M., & Dudek, S. M. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0598-7 · Cited by 69 · see citing works
Cellular, molecular, and genetic substrates underlying the impact of nicotine on learning
Gould, T. J., & Leach, P. T. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.08.004 · Cited by 68 · see citing works
The Human Hippocampus in Parkinson’s Disease: An Integrative Stereological and Proteomic Study
Villar‐Conde, S., Astillero‐Lopez, V., González-Rodríguez, M., Villanueva‐Anguita, P., Saiz‐Sánchez, D., Martı́nez-Marcos, A., Flores‐Cuadrado, A., & Úbeda‐Bañón, I. (2021) · Journal of Parkinson s Disease · doi:10.3233/jpd-202465 · Cited by 67 · see citing works
Three brain states in the hippocampus and cortex
Kay, K., & Frank, L. M. (2018) · Hippocampus · doi:10.1002/hipo.22956 · Cited by 63 · see citing works
Liu, A. K. L., Chau, T. W., Lim, E., Ahmed, I., Chang, R. C., Kalaitzakis, M. E., Graeber, M. B., Gentleman, S., & Pearce, R. K. B. (2019) · Acta Neuropathologica Communications · doi:10.1186/s40478-019-0717-3 · Cited by 64 · see citing works
Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2
Dasgupta, A., Baby, N., Krishna, K., Hakim, M., Wong, Y. P., Behnisch, T., Soong, T. W., & Sajikumar, S. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711267114 · Cited by 61 · see citing works
Architecture of spatial circuits in the hippocampal region
Witter, M. P., Canto, C. B., Couey, J. J., Koganezawa, N., & O’Reilly, K. C. (2013) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2012.0515 · Cited by 58 · see citing works
Hippocampal area CA2: an emerging modulatory gateway in the hippocampal circuit
Benoy, A., Dasgupta, A., & Sajikumar, S. (2018) · Experimental Brain Research · doi:10.1007/s00221-018-5187-5 · Cited by 57 · see citing works
Regulation of synaptic plasticity in hippocampal area CA2
Carstens, K. E., & Dudek, S. M. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.07.008 · Cited by 55 · see citing works
Pimpinella, D., Mastrorilli, V., Giorgi, C., Coemans, S., Lecca, S., Lalive, A. L., Ostermann, H., Fuchs, E. C., Monyer, H., Mele, A., et al. (2021) · eLife · doi:10.7554/elife.65580 · Cited by 54 · see citing works
Advances in the study of cholinergic circuits in the central nervous system
He, G., Yang, L., Deng, H., & Zuo, H. (2023) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51920 · Cited by 49 · see citing works
Inhibitory Plasticity Permits the Recruitment of CA2 Pyramidal Neurons by CA3
Nasrallah, K., Piskorowski, R. A., & Chevaleyre, V. (2015) · eNeuro · doi:10.1523/eneuro.0049-15.2015 · Cited by 49 · see citing works
Proximodistal Organization of the CA2 Hippocampal Area
Fernández‐Lamo, I., Gómez-Domínguez, D., Sánchez-Aguilera, A., Oliva, A., Morales, A. V., Valero, M., Cid, E., Berényi, A., & de la Prida, L. M. (2018) · Cell Reports · doi:10.1016/j.celrep.2019.01.060 · Cited by 45 · see citing works
Inoue, K., Ford, C. L., Horie, K., & Young, L. J. (2022) · Journal of Comparative Neurology · doi:10.1002/cne.25382 · Cited by 45 · see citing works
Bilash, O. M., Chavlis, S., Johnson, C. D., Poirazi, P., & Basu, J. (2023) · Cell Reports · doi:10.1016/j.celrep.2022.111962 · Cited by 50 · see citing works
Neural Activity Patterns Underlying Spatial Coding in the Hippocampus
Sosa, M., Gillespie, A. K., & Frank, L. M. (2016) · Current topics in behavioral neurosciences · doi:10.1007/7854_2016_462 · Cited by 39 · see citing works
Critical appraisal of pathology transmission in the α-synuclein fibril model of Lewy body disorders
Nouraei, N., Mason, D. M., Miner, K. M., Carcella, M. A., Bhatia, T. N., Dumm, B. K., Soni, D., Johnson, D. A., Luk, K. C., & Leak, R. K. (2017) · Experimental Neurology · doi:10.1016/j.expneurol.2017.10.017 · Cited by 40 · see citing works
Social Context, Stress, Neuropsychiatric Disorders, and the Vasopressin 1b Receptor
Caldwell, H. K., Aulino, E. A., Rodriguez, K. M., Witchey, S. K., & Yaw, A. M. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00567 · Cited by 39 · see citing works
Review: Revisiting the human cholinergic nucleus of the diagonal band of Broca
Liu, A. K. L., Lim, E., Ahmed, I., Chang, R. C., Pearce, R. K. B., & Gentleman, S. (2018) · Neuropathology and Applied Neurobiology · doi:10.1111/nan.12513 · Cited by 39 · see citing works
Adult Neurogenesis under Control of the Circadian System
Ali, A. A. H., & von Gall, C. (2022) · Cells · doi:10.3390/cells11050764 · Cited by 38 · see citing works
Neuropeptides and small-molecule amine transmitters: cooperative signaling in the nervous system
Eiden, L. E., Hernández, V. S., Jiang, S. Z., & Zhang, L. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04451-7 · Cited by 36 · see citing works
Kooshki, R., Abbasnejad, M., Esmaeili‐Mahani, S., & Raoof, M. (2016) · Physiology & Behavior · doi:10.1016/j.physbeh.2016.01.031 · Cited by 36 · see citing works
Alexander, G. M., Riddick, N. V., McCann, K. E., Lustberg, D. J., Moy, S. S., & Dudek, S. M. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107044 · Cited by 33 · see citing works
Manohar, S., Chen, G., Ding, D., Liu, L., Wang, J., Chen, Y., Chen, L., & Salvi, R. (2022) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2022.871223 · Cited by 37 · see citing works
Primate hippocampus size and organization are predicted by sociality but not diet
Todorov, O. S., Weisbecker, V., Gilissen, E., Zilles, K., & de Sousa, A. A. (2019) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.2019.1712 · Cited by 37 · see citing works
A unified circuit for social behavior
Modi, M. E., & Şahin, M. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.08.010 · Cited by 34 · see citing works
Piskorowski, R. A., & Chevaleyre, V. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.04.015 · Cited by 33 · see citing works
Dynamic Hippocampal CA2 Responses to Contextual Spatial Novelty
Bhasin, G., & Nair, I. R. (2022) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2022.923911 · Cited by 31 · see citing works
Hippocampal area CA2: properties and contribution to hippocampal function
Robert, V., Cassim, S., Chevaleyre, V., & Piskorowski, R. A. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2769-7 · Cited by 30 · see citing works
Hernández‐Pérez, O. R., Hernández, V. S., Nava-Kopp, A. T., Barrio, R. A., Seifi, M., Swinny, J. D., Eiden, L. E., & Zhang, L. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00196 · Cited by 30 · see citing works
c-Fos expression predicts long-term social memory retrieval in mice
Dias, T. L., Golino, H. F., Oliveira, V. E. D. M., Moraes, M. F. D., & Pereira, G. S. (2016) · Behavioural Brain Research · doi:10.1016/j.bbr.2016.07.030 · Cited by 30 · see citing works
Life and death in the hippocampus: What's bad?
Santos, V. R., de Melo, I. S., Pacheco, A. L. D., & de Castro, O. W. (2019) · Epilepsy & Behavior · doi:10.1016/j.yebeh.2019.106595 · Cited by 29 · see citing works
Regulator of G Protein Signaling 14
Evans, P. R., Dudek, S. M., & Hepler, J. R. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.03.006 · Cited by 26 · see citing works
Helton, T. D., Zhao, M., Farris, S., & Dudek, S. M. (2018) · Hippocampus · doi:10.1002/hipo.23012 · Cited by 25 · see citing works
Alteration of Neural Pathways and Its Implications in Alzheimer’s Disease
Kim, S., Nam, Y., Kim, H. S., Jung, H., Jeon, S. G., Hong, S. B., & Moon, M. (2022) · Biomedicines · doi:10.3390/biomedicines10040845 · Cited by 28 · see citing works
Alexander, G. M., Nikolova, V. D., Stöber, T. M., Gruzdev, A., Moy, S. S., & Dudek, S. M. (2024) · Journal of Neuroscience · doi:10.1523/jneurosci.1626-24.2024 · Cited by 24 · see citing works
The Neural Circuit Architecture of Social Hierarchy in Rodents and Primates
Ferreira‐Fernandes, E., & Peça, J. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.874310 · Cited by 20 · see citing works
Quinn, J. C. (2015) · Journal of Parasitology Research · doi:10.1155/2015/368064 · Cited by 24 · see citing works
Sex-Specific Differences in Oxytocin Receptor Expression and Function for Parental Behavior
Mitre, M., Kranz, T. M., Marlin, B. J., Schiavo, J. K., Erdjument‐Bromage, H., Zhang, X., Minder, J. L., Neubert, T. A., Hackett, T. A., Chao, M. V., et al. (2017) · Gender and the Genome · doi:10.1089/gg.2017.0017 · Cited by 22 · see citing works
Evaluation of WGA–Cre-dependent topological transgene expression in the rodent brain
Libbrecht, S., den Haute, C. V., Malinouskaya, L., Gijsbers, R., & Baekelandt, V. (2016) · Brain Structure and Function · doi:10.1007/s00429-016-1241-x · Cited by 23 · see citing works
Anatomy and Function of the Hypothalamus
Pop, M. G., Crivii, C. B., & Opincariu, I. (2018) · IntechOpen eBooks · doi:10.5772/intechopen.80728 · Cited by 23 · see citing works
Chai, A., Chen, X.-F., Xu, X.-S., Zhang, N., Li, M., Li, J., Zhang, L., Zhang, D., Zhang, X., Mao, R., et al. (2021) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2021.699315 · Cited by 23 · see citing works
CA2 orchestrates hippocampal network dynamics
Oliva, A., Fernández‐Ruiz, A., & Karaba, L. A. (2022) · Hippocampus · doi:10.1002/hipo.23495 · Cited by 24 · see citing works
Stöber, T. M., Lehr, A. B., Hafting, T., Kumar, A., & Fyhn, M. (2020) · Hippocampus · doi:10.1002/hipo.23256 · Cited by 20 · see citing works
Benoy, A., Ibrahim, M. Z. B., Behnisch, T., & Sajikumar, S. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2885-20.2021 · Cited by 20 · see citing works
Diethorn, E. J., & Gould, E. (2022) · Hippocampus · doi:10.1002/hipo.23476 · Cited by 20 · see citing works
Radzicki, D., Chong, S., & Dudek, S. M. (2023) · Hippocampus · doi:10.1002/hipo.23509 · Cited by 20 · see citing works
Olfactory bulb astrocytes link social transmission of stress to cognitive adaptation in male mice
Gómez-Sotres, P., Skupio, U., Tor, T. D., Julio‐Kalajzić, F., Cannich, A., Gisquet, D., Río, I. B., Drago, F., Puente, N., Grandes, P., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-51416-4 · Cited by 21 · see citing works
Zhang, L., & Eiden, L. E. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2958-z · Cited by 21 · see citing works
Development of the hippocampal CA2 region and the emergence of social recognition
Diethorn, E. J., & Gould, E. (2023) · Developmental Neurobiology · doi:10.1002/dneu.22919 · Cited by 20 · see citing works
Integration of the CA2 region in the hippocampal network during epileptogenesis
Kilias, A., Tulke, S., Barheier, N., Ruther, P., & Häussler, U. (2022) · Hippocampus · doi:10.1002/hipo.23479 · Cited by 20 · see citing works
Zhang, L., Hernández, V. S., Zetter, M. A., & Eiden, L. E. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12831 · Cited by 19 · see citing works
Hippocampal area CA2: interneuron disfunction during pathological states
Piskorowski, R. A., & Chevaleyre, V. (2023) · Frontiers in Neural Circuits · doi:10.3389/fncir.2023.1181032 · Cited by 20 · see citing works
Amaral, D. G., Lavenex, P., & Insausti, R. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780190065324.003.0003 · Cited by 19 · see citing works
Russo, C., Russo, A., Pellitteri, R., & Stanzani, S. (2017) · Neuroscience Letters · doi:10.1016/j.neulet.2017.05.049 · Cited by 19 · see citing works
Early hippocampal hyperexcitability and synaptic reorganization in mouse models of amyloidosis
Ray, A., Loghinov, I., Ravindranath, V., & Barth, A. L. (2024) · iScience · doi:10.1016/j.isci.2024.110629 · Cited by 17 · see citing works
Richardson, T. E., Walker, J. M., Farrell, K. W., Oliveira, T. G., White, C. L., & Crary, J. F. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02943-x · Cited by 21 · see citing works
Stability of medial entorhinal cortex representations over time
Diehl, G. W., Hon, O. J., Leutgeb, S., & Leutgeb, J. K. (2018) · Hippocampus · doi:10.1002/hipo.23017 · Cited by 21 · see citing works
- Authors
- Cui, Z., Gerfen, C. R., & Young, W. S.
- Affiliations
- National Institutes of Health (US)
- Venue
- Journal of Comparative Neurology
- Publisher
- Wiley
- Published
- 2013-04-04
- Volume
- 521
- Issue
- 8
- Pages
- 1844-1866
- ISSN
- 0021-9967 (ISSN-L)
- 1096-9861
- PMC
- PMC3798086
- OpenAlex
- W1846418424
- Cited by
- 214
- References
- 101
- Citations by year
- 2026: 16 · 2025: 15 · 2024: 13 · 2023: 18 · 2022: 21 · 2021: 16 · 2020: 16 · 2019: 16 · 2018: 20 · 2017: 13 · 2016: 22 · 2015: 11 · 2014: 11 · 2013: 6
- FWCI
- 4.53
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- The Journal of Comparative Neurology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (Z01-MH-002498-23, ZIAMH002498, Z01MH002498, Z01-MH-002947-23)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- hippocampus, hypothalamus, paraventricular nucleus, vasopressin, entorhinal cortex, medial septum, diagonal band of Broca, median raphe nucleus, retrograde tracing, memory processes
- MeSH terms
- Adenoviridae, Animals, Brain, Hypothalamus, Indoles, Functional Laterality, Male, Neural Pathways, Neurons, Stilbamidines, Gene Transfer Techniques, Entorhinal Cortex, Plant Lectins, Green Fluorescent Proteins, Mice, CA2 Region, Hippocampal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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