Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2
Open accessAbstract
The vasopressin 1b receptor (Avpr1b) is critical for social memory and social aggression in rodents, yet little is known about its specific roles in these behaviors. Some clues to Avpr1b function can be gained from its profile of expression in the brain, which is largely limited to the pyramidal neurons of the CA2 region of the hippocampus, and from experiments showing that inactivation of the gene or antagonism of the receptor leads to a reduction in social aggression. Here we show that partial replacement of the Avpr1b through lentiviral delivery into the dorsal CA2 region restored the probability of socially motivated attack behavior in total Avpr1b knockout mice, without altering anxiety-like behaviors. To further explore the role of the Avpr1b in this hippocampal region, we examined the effects of Avpr1b agonists on pyramidal neurons in mouse and rat hippocampal slices. We found that selective Avpr1b agonists induced significant potentiation of excitatory synaptic responses in CA2, but not in CA1 or in slices from Avpr1b knockout mice. In a way that is mechanistically very similar to synaptic potentiation induced by oxytocin, Avpr1b agonist-induced potentiation of CA2 synapses relies on NMDA (N-methyl-D-aspartic acid) receptor activation, calcium and calcium/calmodulin-dependent protein kinase II activity, but not on cAMP-dependent protein kinase activity or presynaptic mechanisms. Our data indicate that the hippocampal CA2 is important for attacking in response to a male intruder and that the Avpr1b, likely through its role in regulating CA2 synaptic plasticity, is a necessary mediator.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Oxytocin lowers the threshold for depolarizing inputs to induce long-term potentiation (LTP) in hippocampal CA2 and olfactory bulb.
“For example, oxytocin lowers the threshold for depolarizing inputs to induce long-term potentiation (LTP) in hippocampal CA2 (Pagani et al. 2015, Carstens & Dudek 2019) and olfactory bulb (Fang et al. 2008).”
From Oxytocin, Neural Plasticity, and Social Behavior (2021) · cites this paper as Pagani et al. 2015
The Discussion (page unavailable) proposes that oxytocin decreases the threshold for LTP in CA2, supported by potentiation during baseline stimulation. The Results (page unavailable) show potentiation with an oxytocin-receptor agonist, but the paper presents the threshold claim as a proposal rather than an established finding. The olfactory-bulb portion is attributed to Fang et al., not Pagani et al. (LLM, conf=0.86)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
The mouse brain in stereotaxic coordinates
Konsman, J. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00088-x · Cited by 16,796 · see citing works
The Mouse Brain in Stereotaxic Coordinates
Paxinos, G. (2001) · Cited by 12,859 · see citing works
A Third-Generation Lentivirus Vector with a Conditional Packaging System
Dull, T., Zufferey, R., Kelly, M., Mandel, R. J., Nguyen, M., Trono, D., & Naldini, L. (1998) · Journal of Virology · doi:10.1128/jvi.72.11.8463-8471.1998 · Cited by 3,341 · see citing works
de Nó, R. L. (1934) · Cited by 1,974 · see citing works
Oxytocin and vasopressin in the human brain: social neuropeptides for translational medicine
Meyer-Lindenberg, A., Domes, G., Kirsch, P., & Heinrichs, M. (2011) · Nature Reviews Neuroscience · doi:10.1038/nrn3044 · Cited by 1,688 · see citing works
(1964) · The Medical Journal of Australia · doi:10.5694/j.1326-5377.1964.tb115841.x · Cited by 1,409 · see citing works
Lantos, P. L. (1985) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.48.5.496 · Cited by 1,154 · see citing works
Intracellular injections of EGTA block induction of hippocampal long-term potentiation
Lynch, G., Larson, J., Kelso, S., Barrionuevo, G., & Schottler, F. (1983) · Nature · doi:10.1038/305719a0 · Cited by 1,116 · see citing works
The hippocampal CA2 region is essential for social memory
Hitti, F. L., & Siegelbaum, S. A. (2014) · Nature · doi:10.1038/nature13028 · Cited by 976 · see citing works
Kainic acid seizures in the rat
Sperk, G. (1994) · Progress in Neurobiology · doi:10.1016/0301-0082(94)90019-1 · Cited by 688 · see citing works
Vasopressin: Behavioral roles of an “original” neuropeptide
Caldwell, H. K., Lee, H.-J., Macbeth, A. H., & Young, W. S. (2008) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2007.10.007 · Cited by 504 · see citing works
Self-citationA reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives
Benes, F. M., Kwok, E. W., Vincent, S. L., & Todtenkopf, M. S. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00138-3 · Cited by 470 · see citing works
Insel, T., Wang, Z., & Ferris, C. (1994) · The Journal of Neuroscience · doi:10.1523/jneurosci.14-09-05381.1994 · Cited by 454 · see citing works
Epilepsy and Neuron Loss in the Hippocampus
Dam, A. M. (1980) · Epilepsia · doi:10.1111/j.1528-1157.1980.tb04315.x · Cited by 413 · see citing works
Vasopressin V1b receptor knockout reduces aggressive behavior in male mice
Wersinger, S. R., Ginns, E. I., O'Carroll, A.-M., Lolait, S. J., & Young III, W. S. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001195 · Cited by 397 · see citing works
Self-citationLoup, F., Tribollet, E., Dubois-Dauphin, M., & Dreifuss, J. J. (1991) · Brain Research · doi:10.1016/0006-8993(91)90345-v · Cited by 378 · see citing works
Oxytocin improves long-lasting spatial memory during motherhood through MAP kinase cascade
Tomizawa, K., Iga, N., Lü, Y.-F., Moriwaki, A., Matsushita, M., Li, S., Miyamoto, O., Itano, T., & Matsui, H. (2003) · Nature Neuroscience · doi:10.1038/nn1023 · Cited by 372 · see citing works
Chakrabarti, B., Dudbridge, F., Kent, L., Wheelwright, S., Hill‐Cawthorne, G., Allison, C., Banerjee‐Basu, S., & Baron‐Cohen, S. (2009) · Autism Research · doi:10.1002/aur.80 · Cited by 295 · see citing works
Reduced Neuronal Size in Posterior Hippocampus of Schizophrenic Patients
Benes, F. M., Sorensen, I., & Bird, E. D. (1991) · Schizophrenia Bulletin · doi:10.1093/schbul/17.4.597 · Cited by 285 · see citing works
Ostrowski, N. L., Lolait, S. J., & Young, W. S. (1994) · Endocrinology · doi:10.1210/endo.135.4.7925112 · Cited by 284 · see citing works
Self-citationLein, E. S., Zhao, X., & Gage, F. H. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4710-03.2004 · Cited by 270 · see citing works
A conditional knockout mouse line of the oxytocin receptor
Lee, H.-J., Caldwell, H. K., Macbeth, A. H., Tolu, S. G., & Young, W. S. (2008) · Endocrinology · doi:10.1210/en.2007-1710 · Cited by 269 · see citing works
Self-citationVasopressin receptor blockade in the anterior hypothalamus suppresses aggression in hamsters
Ferris, C. F., & Potegal, M. (1988) · Physiology & Behavior · doi:10.1016/0031-9384(88)90144-8 · Cited by 259 · see citing works
Aggression and anxiety: social context and neurobiological links
Neumann, I. D. (2010) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2010.00012 · Cited by 238 · see citing works
Bard, P., & Mountcastle, V. B. (1948) · PubMed · Cited by 226 · see citing works
Lee, S. E., Simons, S. B., Heldt, S. A., Zhao, M., Schroeder, J. P., Vellano, C. P., Cowan, D. P., Ramineni, S., Yates, C. K., Feng, Y., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1005362107 · Cited by 224 · see citing works
Self-citationYoung, W. S., Li, J., Wersinger, S. R., & Palkovits, M. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.08.040 · Cited by 222 · see citing works
Self-citationHypothalamic and other connections with dorsal CA2 area of the mouse hippocampus
Cui, Z., Gerfen, C. R., & Young, W. S. (2013) · Journal of Comparative Neurology · doi:10.1002/cne.23263 · Cited by 214 · see citing works
Self-citationNeurogenetics of Aggressive Behavior: Studies in Rodents
Takahashi, A., & Miczek, K. A. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_263 · Cited by 212 · see citing works
Insel, T. R., Gelhard, R., & Shapiro, L. E. (1991) · Neuroscience · doi:10.1016/0306-4522(91)90321-e · Cited by 209 · see citing works
Effect of subcortical lesions on shock-induced aggression in the rat.
Eichelman, B. S. (1971) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0030559 · Cited by 208 · see citing works
Maternal aggression in rodents: brain oxytocin and vasopressin mediate pup defence
Bosch, O. J. (2013) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2013.0085 · Cited by 194 · see citing works
Synaptic Plasticity (and the Lack Thereof) in Hippocampal CA2 Neurons
Zhao, M., Choi, Y., Obrietan, K. H., & Dudek, S. M. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4094-07.2007 · Cited by 181 · see citing works
Self-citationLein, E. S., Callaway, E. M., Albright, T. D., & Gage, F. H. (2005) · Journal of Comparative Neurology · doi:10.1002/cne.20426 · Cited by 158 · see citing works
Frontolimbic lesions and social behavior in the rat
Kolb, B. E., & Nonneman, A. J. (1974) · Physiology & Behavior · doi:10.1016/0031-9384(74)90234-0 · Cited by 143 · see citing works
Vasopressin 1a receptor knockout mice have a subtle olfactory deficit but normal aggression
Wersinger, S. R., Caldwell, H. K., Martinez, L. A., Gold, P. W., Hu, S.-B., & Young, W. S. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00281.x · Cited by 139 · see citing works
Self-citationUpdating hippocampal representations: CA2 joins the circuit
Jones, M. W., & McHugh, T. J. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.07.007 · Cited by 137 · see citing works
Landgraf, R., Neumann, I. D., & Pittman, Q. J. (2008) · Neuroendocrinology · doi:10.1159/000125917 · Cited by 137 · see citing works
Vasopressin and oxytocin receptors
Zingg, H. H. (1996) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(96)80314-4 · Cited by 137 · see citing works
Loup, F., Tribollet, E., Dubois-Dauphin, M., Pizzolato, G., & Dreifuss, J. J. (1989) · Brain Research · doi:10.1016/0006-8993(89)90317-x · Cited by 136 · see citing works
Simons, S. B., Escobedo, Y., Yasuda, R., & Dudek, S. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0904775106 · Cited by 134 · see citing works
Self-citationWersinger, S. R., Kelliher, K. R., Zufall, F., Lolait, S. J., O’Carroll, A., & Young, W. S. (2004) · Hormones and Behavior · doi:10.1016/j.yhbeh.2004.07.004 · Cited by 132 · see citing works
Self-citationWersinger, S. R., Caldwell, H. K., Christiansen, M., & Young, W. S. (2006) · Genes Brain & Behavior · doi:10.1111/j.1601-183x.2006.00294.x · Cited by 130 · see citing works
Self-citationSiegel, A., & Flynn, J. P. (1968) · Brain Research · doi:10.1016/0006-8993(68)90102-9 · Cited by 113 · see citing works
West, D. V., Del‐Favero, J., Aulchenko, Y. S., Oswald, P., Souery, D., Forsgren, T., Sluijs, S., Belkacem, S., Adolfsson, R., Mendlewicz, J., et al. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001420 · Cited by 110 · see citing works
Gal, C. S., Wagnon, J., Tonnerre, B., Roux, R., Garcia, G., Griebel, G., & Aulombard, A. (2006) · CNS Drug Reviews · doi:10.1111/j.1527-3458.2005.tb00035.x · Cited by 110 · see citing works
Zetzsche, T., Preuss, U. W., Frodl, T., Schmitt, G., Seifert, D., Münchhausen, E., Tabrizi, S. D., Leinsinger, G. L., Born, C., Reiser, M. F., et al. (2007) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2006.05.010 · Cited by 102 · see citing works
Sala, M., Caverzasi, E., Lazzaretti, M., Morandotti, N., Vidovich, G. Z. D., Marraffini, E., Gambini, F., Isola, M., Bona, M. D., Rambaldelli, G., et al. (2011) · Journal of Affective Disorders · doi:10.1016/j.jad.2010.11.036 · Cited by 101 · see citing works
Zhang, L., & Hernández, V. S. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2012.10.010 · Cited by 96 · see citing works
Antoni, F. A., Holmes, M. C., Makara, G. B., Kárteszi, M., & László, F. A. (1984) · Peptides · doi:10.1016/0196-9781(84)90080-9 · Cited by 96 · see citing works
Spatial Olfactory Learning Contributes to Place Field Formation in the Hippocampus
Zhang, S., & Manahan‐Vaughan, D. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht239 · Cited by 95 · see citing works
AVP V selective antagonist SSR149415 blocks aggressive behaviors in hamsters
Blanchard, R. J., Griebel, G., Farrokhi, C. B., Markham, C. M., YANG, M., & Blanchard, D. C. (2004) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2004.10.024 · Cited by 94 · see citing works
Hazell, G. G. J., Hindmarch, C. C. T., Pope, G. R., Roper, J. A., Lightman, S. L., Murphy, D., O’Carroll, A., & Lolait, S. J. (2011) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2011.07.002 · Cited by 85 · see citing works
Wersinger, S. R., Temple, J. L., Caldwell, H. K., & Young, W. S. (2008) · Endocrinology · doi:10.1210/en.2007-1056 · Cited by 83 · see citing works
Self-citationHodgson, R. A., Higgins, G. A., Guthrie, D. H., Lu, S. X., Pond, A. J., Mullins, D. E., Guzzi, M. F., Parker, E. M., & Varty, G. B. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2006.12.021 · Cited by 82 · see citing works
Caffeine-induced synaptic potentiation in hippocampal CA2 neurons
Simons, S. B., Caruana, D. A., Zhao, M., & Dudek, S. M. (2011) · Nature Neuroscience · doi:10.1038/nn.2962 · Cited by 82 · see citing works
Self-citationKrémarik, P., Freund‐Mercier, M. J., & Stoeckel, M. E. (1993) · The Journal of Comparative Neurology · doi:10.1002/cne.903330304 · Cited by 80 · see citing works
Shimazaki, T., Iijima, M., & Chaki, S. (2006) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2006.06.032 · Cited by 78 · see citing works
Johnson, A. E., Audigier, S., Rossi, F., Jard, S., Tribollet, E., & Barberis, C. (1993) · Brain Research · doi:10.1016/0006-8993(93)90795-o · Cited by 77 · see citing works
Honkaniemi, J., & Sharp, F. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00401.x · Cited by 77 · see citing works
The vasopressin V1b receptor as a therapeutic target in stress-related disorders
Griebel, G., Simiand, J., Stemmelin, J., Gal, C., & Steinberg, R. (2003) · Current Drug Target -CNS & Neurological Disorders · doi:10.2174/1568007033482850 · Cited by 74 · see citing works
Piskorowski, R. A., & Chevaleyre, V. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-011-0769-4 · Cited by 65 · see citing works
Oxytocin, vasopressin, and related peptides in the regulation of behavior
Choleris, E., Pfaff, D. W., & Kavaliers, M. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.025 · Cited by 62 · see citing works
Tribollet, E., Barberis, C., Dubois‐Dauphin, M., & Dreifuss, J. J. (1992) · Brain Research · doi:10.1016/0006-8993(92)91156-9 · Cited by 58 · see citing works
Vasopressin induction of long‐lasting potentiation of synaptic transmission in the dentate gyrus
Chen, C., Brinton, R. D., Shors, T. J., & Thompson, R. F. (1993) · Hippocampus · doi:10.1002/hipo.450030211 · Cited by 54 · see citing works
Electrophysiological characterization of CA2 pyramidal cells from epileptic humans
Williamson, A., & Spencer, D. D. (1994) · Hippocampus · doi:10.1002/hipo.450040213 · Cited by 52 · see citing works
Possible genetic association between vasopressin receptor 1B and child aggression
Zai, C. C., Muir, K. E., Nowrouzi, B., Shaikh, S. A., Choi, E., Berall, L., Trépanier, M.-O., Beitchman, J. H., & Kennedy, J. L. (2012) · Psychiatry Research · doi:10.1016/j.psychres.2012.07.031 · Cited by 43 · see citing works
Watson, R. E., Edinger, H. M., & Siegel, A. (1983) · Brain Research · doi:10.1016/0006-8993(83)90143-9 · Cited by 40 · see citing works
The acute intoxicating effects of ethanol are not dependent on the vasopressin 1a or 1b receptors
Caldwell, H. K., Stewart, J., Wiedholz, L. M., Millstein, R. A., Iacangelo, A. L., Holmes, A., Young, W. S., & Wersinger, S. R. (2006) · Neuropeptides · doi:10.1016/j.npep.2006.08.001 · Cited by 39 · see citing works
Self-citationChepkova, A. N., French, P. J., de Wied, D., Ontskul, A. H., Ramakers, G. M. J., Skrebitski, V. G., Gispen, W. H., & Urban, I. J. A. (1995) · Brain Research · doi:10.1016/0006-8993(95)01006-7 · Cited by 36 · see citing works
Urban, I. J. A. (1999) · Progress in brain research · doi:10.1016/s0079-6123(08)61576-9 · Cited by 32 · see citing works
Vasopressin Inhibits LTP in the CA2 Mouse Hippocampal Area
Chafaï, M., Corbani, M., Guillon, G., & Desarménien, M. G. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049708 · Cited by 32 · see citing works
Action of vasopressin on CA1 pyramidal neurons in rat hippocampal slices
Mizuno, Y., Oomura, Y., Hori, N., & Carpenter, D. O. (1984) · Brain Research · doi:10.1016/0006-8993(84)90589-4 · Cited by 30 · see citing works
Postweaning, forebrain-specific perturbation of the oxytocin system impairs fear conditioning
Pagani, J. H., Lee, H.-J., & Young, W. S. (2011) · Genes, Brain and Behavior · doi:10.1111/j.1601-183x.2011.00709.x · Cited by 30 · see citing works
Self-citationAn anxiety-like phenotype in mice selectively bred for aggression
Nehrenberg, D. L., Rodriguiz, R. M., Cyr, M., Zhang, X., Lauder, J. M., Gariépy, J., & Wetsel, W. C. (2009) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.02.010 · Cited by 29 · see citing works
Minicomputer monitored social behavior of mice with hippocampus lesions
Ely, D., Greene, E. G., & Henry, J. P. (1976) · Behavioral Biology · doi:10.1016/s0091-6773(76)91082-8 · Cited by 27 · see citing works
Peptidergic transmission in the brain. I. Vasopressin-like signal in the hippocampus
Albeck, D. S., Smock, T., McMechen, P., Purves, D., & Floyd, L. (1990) · Brain Research · doi:10.1016/0006-8993(90)90219-2 · Cited by 23 · see citing works
Hippocampal neurofibrillary tangle changes and aggressive behaviour in dementia
Lai, M. K. P., Chen, C., Hope, T., & Esiri, M. M. (2010) · Neuroreport · doi:10.1097/wnr.0b013e3283407204 · Cited by 22 · see citing works
Inhibition by [Arg8]-Vasopressin of Long Term Potentiation in Guinea Pig Hippocampal Slice
Sakurai, E., Maeda, T., Kaneko, S., Akaike, A., & Satoh, M. (1998) · The Japanese Journal of Pharmacology · doi:10.1254/jjp.77.103 · Cited by 9 · see citing works
Antidromic activation of a peptidergic pathway in the limbic system of the male rat
Albeck, D. S., Bullock, N., Marrs, K., Cooper, R. N., Smock, T., & Vries, G. J. D. (1993) · Brain Research · doi:10.1016/0006-8993(93)91587-i · Cited by 7 · see citing works
Амикишиева, А. В., Ilnitskaya, S. I., Nikolin, V. P., & Na, P. (2011) · PubMed · Cited by 5 · see citing works
The roles of vasopressin and oxytocin in aggression
Pagani, J. H., Wersinger, S. R., & Young, W. S. (2013) · Cambridge University Press eBooks · doi:10.1017/cbo9781139017855.014 · Cited by 4 · see citing works
Self-citationDm, P. (1979) · PubMed · Cited by 1 · see citing works
Flagged first, then by citations
1 of the 85 references couldn’t be matched to a known paper.
Research works printed but not linked: 1
- [80]Save E Nerad L Poucet B Contribution of multiple sensory information to place field stability in hippocampal place cells Hippocampus 2000 10 1 64 76 10706218
Cited by
Sorted by citations
Oxytocin, Neural Plasticity, and Social Behavior
Froemke, R. C., & Young, L. J. (2021) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-102320-102847 · Cited by 487 · see citing works
Rediscovering area CA2: unique properties and functions
Dudek, S. M., Alexander, G. M., & Farris, S. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2015.22 · Cited by 329 · see citing works
Self-citationMarmosets: A Neuroscientific Model of Human Social Behavior
Miller, C. T., Freiwald, W. A., Leopold, D. A., Mitchell, J. F., Silva, A. C., & Wang, X. (2016) · Neuron · doi:10.1016/j.neuron.2016.03.018 · Cited by 329 · see citing works
Hippocampal CA2 activity patterns change over time to a larger extent than between spatial contexts
Mankin, E. A., Diehl, G. W., Sparks, F. T., Leutgeb, S., & Leutgeb, J. K. (2015) · Neuron · doi:10.1016/j.neuron.2014.12.001 · Cited by 279 · see citing works
A hippocampal circuit linking dorsal CA2 to ventral CA1 critical for social memory dynamics
Meira, T., Leroy, F., Buss, E. W., Oliva, A., Park, J., & Siegelbaum, S. A. (2018) · Nature Communications · doi:10.1038/s41467-018-06501-w · Cited by 310 · see citing works
A distributed network for social cognition enriched for oxytocin receptors
Mitre, M., Marlin, B. J., Schiavo, J. K., Morina, E., Norden, S. E., Hackett, T. A., Aoki, C. J., Chao, M. V., & Froemke, R. C. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.2409-15.2016 · Cited by 305 · see citing works
Perineuronal Nets Suppress Plasticity of Excitatory Synapses on CA2 Pyramidal Neurons
Carstens, K. E., Phillips, M. L., Pozzo-Miller, L., Weinberg, R. J., & Dudek, S. M. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.0245-16.2016 · Cited by 271 · see citing works
Self-citationHippocampal CA2 sharp-wave ripples reactivate and promote social memory
Oliva, A., Fernández-Ruiz, A., Leroy, F., & Siegelbaum, S. A. (2020) · Nature · doi:10.1038/s41586-020-2758-y · Cited by 268 · see citing works
A circuit from hippocampal CA2 to lateral septum disinhibits social aggression
Leroy, F., Park, J. M., Asok, A., Brann, D. H., Meira, T., Boyle, L. M., Buss, E. W., Kandel, E. R., & Siegelbaum, S. A. (2018) · Nature · doi:10.1038/s41586-018-0772-0 · Cited by 277 · see citing works
The Corticohippocampal Circuit, Synaptic Plasticity, and MemoryPreprint
Basu, J., & Siegelbaum, S. A. (2015) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a021733 · Cited by 244 · see citing works
Targeted activation of the hippocampal CA2 area strongly enhances social memory
Smith, A. S., Williams Avram, S. K., Cymerblit-Sabba, A., Song, J., & Young, W. S. (2016) · Molecular Psychiatry · doi:10.1038/mp.2015.189 · Cited by 236 · see citing works
Self-citationLesions to the <scp>CA</scp>2 region of the hippocampus impair social memory in mice
Stevenson, E. L., & Caldwell, H. K. (2014) · European Journal of Neuroscience · doi:10.1111/ejn.12689 · Cited by 222 · see citing works
Oxytocin and vasopressin: powerful regulators of social behavior
Caldwell, H. K. (2017) · The Neuroscientist · doi:10.1177/1073858417708284 · Cited by 216 · see citing works
Social and novel contexts modify hippocampal CA2 representations of space
Alexander, G. M., Farris, S., Pirone, J. R., Zheng, C., Colgin, L. L., & Dudek, S. M. (2016) · Nature Communications · doi:10.1038/ncomms10300 · Cited by 191 · see citing works
Self-citationPiskorowski, R. A., Nasrallah, K., Diamantopoulou, A., Mukai, J., Hassan, S. I., Siegelbaum, S. A., Gogos, J. A., & Chevaleyre, V. (2016) · Neuron · doi:10.1016/j.neuron.2015.11.036 · Cited by 180 · see citing works
Lin, Y.-T., Hsieh, T.-Y., Tsai, T.-C., Chen, C.-C., Huang, C.-C., & Hsu, K.-S. (2018) · The Journal of Neuroscience · doi:10.1523/jneurosci.1896-17.2017 · Cited by 165 · see citing works
Oxytocin transforms firing mode of CA2 hippocampal neurons
Tirko, N. N., Eyring, K. W., Carcea, I., Mitre, M., Chao, M. V., Froemke, R. C., & Tsien, R. W. (2018) · Neuron · doi:10.1016/j.neuron.2018.09.008 · Cited by 157 · see citing works
Rutigliano, G., Rocchetti, M., Paloyelis, Y., Gilleen, J., Sardella, A., Cappucciati, M., Palombini, E., Dell’Osso, L., Caverzasi, E., Politi, P., et al. (2016) · Psychiatry Research · doi:10.1016/j.psychres.2016.04.117 · Cited by 149 · see citing works
“, 2002), and viral gene transfer (Pagani et al., 2014)).”
The neural circuitry of social homeostasis: Consequences of acute versus chronic social isolation
Lee, C. R., Chen, A., & Tye, K. M. (2021) · Cell · doi:10.1016/j.cell.2021.02.028 · Cited by 138 · see citing works
Diversity of oxytocin neurones: Beyond magno‐ and parvocellular cell types?
Althammer, F., & Grinevich, V. (2018) · Journal of Neuroendocrinology · doi:10.1111/jne.12549 · Cited by 138 · see citing works
Long‐term plasticity in the hippocampus: maintaining within and ‘tagging’ between synapses
Bin Ibrahim, M. Z., Benoy, A., & Sajikumar, S. (2022) · The FEBS Journal · doi:10.1111/febs.16065 · Cited by 137 · see citing works
Oxytocin, vasopressin, and the motivational forces that drive social behaviors
Caldwell, H. K., & Albers, H. E. (2015) · Current Topics in Behavioral Neurosciences · doi:10.1007/7854_2015_390 · Cited by 129 · see citing works
Cataldo, I., Azhari, A., & Esposito, G. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00027 · Cited by 95 · see citing works
Lin, Y.-T., & Hsu, K. (2018) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2018.10.003 · Cited by 97 · see citing works
Farris, S., Ward, J. M., Carstens, K. E., Samadi, M., Wang, Y., & Dudek, S. M. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.08.093 · Cited by 94 · see citing works
Self-citationSocial memory engram in the hippocampus
Okuyama, T. (2018) · Neuroscience Research · doi:10.1016/j.neures.2017.05.007 · Cited by 95 · see citing works
Leroy, F., Brann, D. H., Meira, T., & Siegelbaum, S. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.07.036 · Cited by 91 · see citing works
Is AD a Stress-Related Disorder? Focus on the HPA Axis and Its Promising Therapeutic Targets
Canet, G., Hernandez, C., Zussy, C., Chevallier, N., Desrumaux, C. M., & Givalois, L. (2019) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2019.00269 · Cited by 89 · see citing works
Oxytocin and vasopressin in the rodent hippocampus
Cilz, N. I., Cymerblit‐Sabba, A., & Young, W. S. (2018) · Genes Brain & Behavior · doi:10.1111/gbb.12535 · Cited by 88 · see citing works
Self-citationProulx, M. J., Todorov, O. S., Aiken, A. T., & de Sousa, A. A. (2016) · Frontiers in Psychology · doi:10.3389/fpsyg.2016.00064 · Cited by 91 · see citing works
Sex differences in the regulation of offensive aggression and dominance by arginine-vasopressin
Terranova, J. I., Ferris, C. F., & Albers, H. E. (2017) · Frontiers in Endocrinology · doi:10.3389/fendo.2017.00308 · Cited by 85 · see citing works
Stoop, R. (2014) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2014.09.012 · Cited by 84 · see citing works
Dissecting the Fornix in Basic Memory Processes and Neuropsychiatric Disease: A Review
Benear, S. L., Ngo, C. T., & Olson, I. R. (2020) · Brain Connectivity · doi:10.1089/brain.2020.0749 · Cited by 84 · see citing works
Oxytocin and behavior: lessons from knockout mice
Caldwell, H. K., Aulino, E. A., Freeman, A. R., Miller, T. V., & Witchey, S. K. (2017) · Developmental Neurobiology · doi:10.1002/dneu.22431 · Cited by 79 · see citing works
Hippocampal Area CA2: An Overlooked but Promising Therapeutic Target
Chevaleyre, V., & Piskorowski, R. A. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.06.007 · Cited by 80 · see citing works
CA2: A Highly Connected Intrahippocampal Relay
Middleton, S. J., & McHugh, T. J. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-080719-100343 · Cited by 79 · see citing works
Sun, Q., Srinivas, K. V., Sotayo, A. O., & Siegelbaum, S. A. (2014) · eLife · doi:10.7554/elife.04551 · Cited by 79 · see citing works
Zhang, L., Hernández, V. S., Vázquez‐Juárez, E., Chay, F. K., & Barrio, R. A. (2016) · Frontiers in Neural Circuits · doi:10.3389/fncir.2016.00013 · Cited by 76 · see citing works
Stress and Seizures: Space, Time and Hippocampal Circuits
Gunn, B. G., & Baram, T. Z. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2017.08.004 · Cited by 72 · see citing works
CA2 beyond social memory: Evidence for a fundamental role in hippocampal information processing
Lehr, A. B., Kumar, A., Tetzlaff, C., Hafting, T., Fyhn, M., & Stöber, T. M. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.03.020 · Cited by 74 · see citing works
The role of oxytocin and vasopressin dysfunction in cognitive impairment and mental disorders
Abramova, O. V., Zorkina, Y., Ushakova, V. M., Zubkov, E. A., Morozova, A. Y., & Chekhonin, V. P. (2020) · Neuropeptides · doi:10.1016/j.npep.2020.102079 · Cited by 74 · see citing works
Novel role for mineralocorticoid receptors in control of a neuronal phenotype
McCann, K. E., Lustberg, D. J., Shaughnessy, E. K., Carstens, K. E., Farris, S., Alexander, G. M., Radzicki, D., Zhao, M., & Dudek, S. M. (2019) · Molecular Psychiatry · doi:10.1038/s41380-019-0598-7 · Cited by 69 · see citing works
Self-citationCA2 neuronal activity controls hippocampal low gamma and ripple oscillations
Alexander, G. M., Brown, L. Y., Farris, S., Lustberg, D. J., Pantazis, C. B., Gloss, B. R., Plummer, N. W., Riddick, N. V., Moy, S. S., Jensen, P., et al. (2018) · eLife · doi:10.7554/elife.38052 · Cited by 73 · see citing works
Self-citationNeuropeptidergic regulation of pair-bonding and stress buffering: Lessons from voles
Gobrogge, K. L., & Wang, Z. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.08.010 · Cited by 62 · see citing works
Srinivas, K. V., Buss, E. W., Sun, Q., Santoro, B., Takahashi, H., Nicholson, D. A., & Siegelbaum, S. A. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2219-16.2017 · Cited by 62 · see citing works
ASD and Genetic Associations with Receptors for Oxytocin and Vasopressin—AVPR1A, AVPR1B, and OXTR
Francis, S. M., Kim, S., Kistner‐Griffin, E., Guter, S. J., Cook, E. H., & Jacob, S. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00516 · Cited by 62 · see citing works
Substance P induces plasticity and synaptic tagging/capture in rat hippocampal area CA2
Dasgupta, A., Baby, N., Krishna, K., Hakim, M., Wong, Y. P., Behnisch, T., Soong, T. W., & Sajikumar, S. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1711267114 · Cited by 61 · see citing works
Pagani, J. H., Williams, S. K., Cui, Z., Song, J., Mezey, É., Senerth, J. M., Baumann, M. H., & Young, W. S. (2015) · Genes Brain & Behavior · doi:10.1111/gbb.12202 · Cited by 60 · see citing works
Self-citationRGS14 Restricts Plasticity in Hippocampal CA2 by Limiting Postsynaptic Calcium Signaling
Evans, P. R., Parra-Bueno, P., Smirnov, M. S., Lustberg, D. J., Dudek, S. M., Hepler, J. R., & Yasuda, R. (2018) · eNeuro · doi:10.1523/eneuro.0353-17.2018 · Cited by 57 · see citing works
Self-citationNew opportunities in vasopressin and oxytocin research: a perspective from the amygdala.
Stoop, R., Hegoburu, C., & van den Burg, E. (2015) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-071714-033904 · Cited by 56 · see citing works
Hippocampal area CA2: an emerging modulatory gateway in the hippocampal circuit
Benoy, A., Dasgupta, A., & Sajikumar, S. (2018) · Experimental Brain Research · doi:10.1007/s00221-018-5187-5 · Cited by 57 · see citing works
Perineuronal net degradation rescues CA2 plasticity in a mouse model of Rett syndrome
Carstens, K. E., Lustberg, D. J., Shaughnessy, E. K., McCann, K. E., Alexander, G. M., & Dudek, S. M. (2021) · Journal of Clinical Investigation · doi:10.1172/jci137221 · Cited by 57 · see citing works
Self-citationDaskalakis, N. P., Meijer, O. C., & de Kloet, E. R. (2022) · Neurobiology of Stress · doi:10.1016/j.ynstr.2022.100455 · Cited by 58 · see citing works
Regulation of synaptic plasticity in hippocampal area CA2
Carstens, K. E., & Dudek, S. M. (2019) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.07.008 · Cited by 55 · see citing works
Self-citationPalmitoylation as a Functional Regulator of Neurotransmitter Receptors
Naumenko, V. S., & Ponimaskin, E. G. (2018) · Neural Plasticity · doi:10.1155/2018/5701348 · Cited by 55 · see citing works
Oxytocin and excitation/inhibition balance in social recognition
Lopatina, O. L., Komleva, Y. K., Gorina, Y. V., Olovyannikova, R. Y., Труфанова, Л. В., Hashimoto, T., Takahashi, T., Kikuchi, M., Minabe, Y., Higashida, H., et al. (2018) · Neuropeptides · doi:10.1016/j.npep.2018.09.003 · Cited by 51 · see citing works
Routing Hippocampal Information Flow through Parvalbumin Interneuron Plasticity in Area CA2
Nasrallah, K., Therreau, L., Robert, V., Huang, A. J. Y., McHugh, T. J., Piskorowski, R. A., & Chevaleyre, V. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.03.014 · Cited by 50 · see citing works
Adult-Born Neurons in the Hippocampus Are Essential for Social Memory Maintenance
Cope, E. C., Waters, R. C., Diethorn, E. J., Pagliai, K. A., Dias, C. G., Tsuda, M. C., Cameron, H. A., & Gould, E. (2020) · eNeuro · doi:10.1523/eneuro.0182-20.2020 · Cited by 48 · see citing works
Distinct functions of ventral CA1 and dorsal CA2 in social memory
Watarai, A., Tao, K., Wang, M., & Okuyama, T. (2021) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2020.12.008 · Cited by 46 · see citing works
Proximodistal Organization of the CA2 Hippocampal Area
Fernández‐Lamo, I., Gómez-Domínguez, D., Sánchez-Aguilera, A., Oliva, A., Morales, A. V., Valero, M., Cid, E., Berényi, A., & de la Prida, L. M. (2018) · Cell Reports · doi:10.1016/j.celrep.2019.01.060 · Cited by 45 · see citing works
Cell type specificity of glucocorticoid signaling in the adult mouse hippocampus
Viho, E. M. G., Buurstede, J. C., Berkhout, J. B., Mahfouz, A. E., & Meijer, O. C. (2021) · Journal of Neuroendocrinology · doi:10.1111/jne.13072 · Cited by 46 · see citing works
Aggression in non‐human vertebrates: Genetic mechanisms and molecular pathways
Freudenberg, F., Gutiérrez, H. C., Post, A. M., Reif, A., & Norton, W. (2015) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.32358 · Cited by 44 · see citing works
Young, W. S., & Song, J. (2020) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2020.00040 · Cited by 42 · see citing works
Self-citationWalker, S. E., Zanoletti, O., Guillot de Suduiraut, I., & Sandi, C. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.06.011 · Cited by 40 · see citing works
Stohn, J. P., Martinez, M. E., Zafer, M., López-Espíndola, D., Keyes, L. M., & Hernández, A. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12400 · Cited by 41 · see citing works
Oxytocin Receptor Signaling in Vascular Function and Stroke
McKay, E. C., & Counts, S. (2020) · Frontiers in Neuroscience · doi:10.3389/fnins.2020.574499 · Cited by 41 · see citing works
Neural Activity Patterns Underlying Spatial Coding in the Hippocampus
Sosa, M., Gillespie, A. K., & Frank, L. M. (2016) · Current topics in behavioral neurosciences · doi:10.1007/7854_2016_462 · Cited by 39 · see citing works
Social Context, Stress, Neuropsychiatric Disorders, and the Vasopressin 1b Receptor
Caldwell, H. K., Aulino, E. A., Rodriguez, K. M., Witchey, S. K., & Yaw, A. M. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00567 · Cited by 39 · see citing works
Dasgupta, A., Lim, Y. J., Kumar, K., Baby, N., Pang, K. K. L., Benoy, A., Behnisch, T., & Sajikumar, S. (2020) · eLife · doi:10.7554/elife.55344 · Cited by 38 · see citing works
Cid-Jofré, V., Moreno, M., Reyes-Parada, M. I., & Renard, G. M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222112077 · Cited by 39 · see citing works
SorCS2 is required for social memory and trafficking of the NMDA receptor
Yang, J., Ma, Q., Dincheva, I., Giza, J. I., Jing, D., Marinic, T. E., Milner, T. A., Rajadhyaksha, A. M., Lee, F. S., & Hempstead, B. L. (2020) · Molecular Psychiatry · doi:10.1038/s41380-020-0650-7 · Cited by 35 · see citing works
Neuropeptides and small-molecule amine transmitters: cooperative signaling in the nervous system
Eiden, L. E., Hernández, V. S., Jiang, S. Z., & Zhang, L. (2022) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-022-04451-7 · Cited by 36 · see citing works
3‐Hz subthreshold oscillations of CA2 neurons In vivo
Matsumoto, N., Okamoto, K., Yuki, T., & Ikegaya, Y. (2016) · Hippocampus · doi:10.1002/hipo.22657 · Cited by 37 · see citing works
Alexander, G. M., Riddick, N. V., McCann, K. E., Lustberg, D. J., Moy, S. S., & Dudek, S. M. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.107044 · Cited by 33 · see citing works
Self-citationUnified Classification of Molecular, Network, and Endocrine Features of Hypothalamic Neurons
Romanov, R. A., Alpár, A., Hökfelt, T. G. M., & Harkany, T. (2019) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-070918-050414 · Cited by 35 · see citing works
Cumming, M. J., Thompson, M. A., & McCormick, C. M. (2014) · Developmental Psychobiology · doi:10.1002/dev.21252 · Cited by 33 · see citing works
Hippocampal area CA2: properties and contribution to hippocampal function
Robert, V., Cassim, S., Chevaleyre, V., & Piskorowski, R. A. (2018) · Cell and Tissue Research · doi:10.1007/s00441-017-2769-7 · Cited by 30 · see citing works
Bayerl, D. S., Kaczmarek, V., Jurek, B., van den Burg, E. H., Neumann, I. D., Gaßner, B. M., Klampfl, S. M., & Bosch, O. J. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.12.003 · Cited by 28 · see citing works
Evans, P. R., Gerber, K. J., Dammer, E. B., Duong, D. M., Goswami, D., Lustberg, D. J., Zou, J., Yang, J. J., Dudek, S. M., Griffin, P. R., et al. (2018) · Journal of Proteome Research · doi:10.1021/acs.jproteome.8b00027 · Cited by 27 · see citing works
Self-citationRGS14 Regulation of Post-Synaptic Signaling and Spine Plasticity in Brain
Harbin, N. H., Bramlett, S. N., Montañez‐Miranda, C., Terzioğlu, G., & Hepler, J. R. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22136823 · Cited by 23 · see citing works
Regulator of G Protein Signaling 14
Evans, P. R., Dudek, S. M., & Hepler, J. R. (2015) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2015.03.006 · Cited by 26 · see citing works
Self-citationGrebe, N. M., Sharma, A., Freeman, S. M., Palumbo, M. C., Patisaul, H. B., Bales, K. L., & Drea, C. M. (2021) · Scientific Reports · doi:10.1038/s41598-021-83342-6 · Cited by 26 · see citing works
Helton, T. D., Zhao, M., Farris, S., & Dudek, S. M. (2018) · Hippocampus · doi:10.1002/hipo.23012 · Cited by 25 · see citing works
Self-citationHodges, T. E., Eltahir, A. M., Patel, S. D., Bredewold, R., Veenema, A. H., & McCormick, C. M. (2019) · Hormones and Behavior · doi:10.1016/j.yhbeh.2019.104579 · Cited by 26 · see citing works
Social odor discrimination and its enhancement by associative learning in the hippocampal CA2 region
Hassan, S., Bigler, S. K., & Siegelbaum, S. A. (2023) · Neuron · doi:10.1016/j.neuron.2023.04.026 · Cited by 25 · see citing works
Social zebrafish: Danio rerio as an emerging model in social neuroendocrinology
Kareklas, K., Teles, M. C., Nunes, A. R., & Oliveira, R. F. (2023) · Journal of Neuroendocrinology · doi:10.1111/jne.13280 · Cited by 23 · see citing works
Barsegyan, A., Atsak, P., Hornberger, W., Jacobson, P. B., van Gaalen, M. M., & Roozendaal, B. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.48 · Cited by 25 · see citing works
Robert, V., Therreau, L., Davatolhagh, M. F., Bernardo-Garcia, F. J., Clements, K. N., Chevaleyre, V., & Piskorowski, R. A. (2020) · The Journal of General Physiology · doi:10.1085/jgp.201912462 · Cited by 25 · see citing works
Lewis, A. S., & Picciotto, M. R. (2019) · Neuropharmacology · doi:10.1016/j.neuropharm.2019.107929 · Cited by 23 · see citing works
Williams Avram, S. K., Lee, H.-J., Fastman, J., Cymerblit-Sabba, A., Smith, A., Vincent, M., Song, J., Granovetter, M. C., Lee, S.-H., Cilz, N. I., et al. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2019.00218 · Cited by 22 · see citing works
Self-citationNeuroendocrine regulation of female aggression
Oliveira, V. E. D. M., & Bakker, J. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.957114 · Cited by 22 · see citing works
CA2 orchestrates hippocampal network dynamics
Oliva, A., Fernández‐Ruiz, A., & Karaba, L. A. (2022) · Hippocampus · doi:10.1002/hipo.23495 · Cited by 24 · see citing works
Stöber, T. M., Lehr, A. B., Hafting, T., Kumar, A., & Fyhn, M. (2020) · Hippocampus · doi:10.1002/hipo.23256 · Cited by 20 · see citing works
Benoy, A., Ibrahim, M. Z. B., Behnisch, T., & Sajikumar, S. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2885-20.2021 · Cited by 20 · see citing works
Radzicki, D., Chong, S., & Dudek, S. M. (2023) · Hippocampus · doi:10.1002/hipo.23509 · Cited by 20 · see citing works
Self-citationZhang, L., & Eiden, L. E. (2018) · Cell and Tissue Research · doi:10.1007/s00441-018-2958-z · Cited by 21 · see citing works
Gerber, K. J., Dammer, E. B., Duong, D. M., Deng, Q., Dudek, S. M., Seyfried, N. T., & Hepler, J. R. (2019) · Journal of Proteome Research · doi:10.1021/acs.jproteome.9b00103 · Cited by 20 · see citing works
Self-citationBlázquez, G., Castañé, A., Saavedra, A., Masana, M., Alberch, J., & Pérez‐Navarro, E. (2019) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00317 · Cited by 20 · see citing works
Individual behavioral trajectories shape whole-brain connectivity in mice
Lopes, J. B., Senko, A. N., Bahnsen, K., Geisler, D., Kim, E., Bernanos, M., Cash, D., Ehrlich, S., Vernon, A. C., & Kempermann, G. (2023) · eLife · doi:10.7554/elife.80379 · Cited by 18 · see citing works
Freeman, A. R., Aulino, E. A., Caldwell, H. K., & Ophir, A. G. (2020) · Journal of Neuroendocrinology · doi:10.1111/jne.12828 · Cited by 19 · see citing works
- Authors
- Pagani, J. H., Zhao, M., Cui, Z., Williams Avram, S. K., Caruana, D. A., Dudek, S. M., & Young, W. S.
- Affiliations
- National Institutes of Health (US)
- Corresponding author
- Dudek, S M
- Young, W S
- Venue
- Molecular Psychiatry
- Published
- 2014-05-27
- Volume
- 20
- Issue
- 4
- Pages
- 490-499
- ISSN
- 1359-4184 (ISSN-L)
- 1476-5578
- PMC
- PMC4562468
- OpenAlex
- W2117023704
- Cited by
- 204
- References
- 85
- Citations by year
- 2026: 11 · 2025: 15 · 2024: 15 · 2023: 19 · 2022: 14 · 2021: 16 · 2020: 22 · 2019: 21 · 2018: 20 · 2017: 16 · 2016: 20 · 2015: 11 · 2014: 4
- FWCI
- 25.22
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Molecular Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Aston Publications Explorer (Aston University) (submittedVersion)
- Funders
- National Institutes of Health
- National Institute of Mental Health (ZIAMH002498, Z01-MH-002498-24, Z01MH002498)
- National Institute of Environmental Health Sciences (Z01ES100221)
- Topics
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- AVPR1B, social aggression, hippocampal CA2, synaptic plasticity, NMDA receptor, CaMKII, oxytocin, social memory, pyramidal neurons
- MeSH terms
- Aggression, Animals, Cell Count, Exploratory Behavior, Female, Male, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Transgenic, Neuronal Plasticity, Synapses, Transduction, Genetic, Lentivirus, Receptors, N-Methyl-D-Aspartate, Rats, Sprague-Dawley, Receptors, Vasopressin, Receptors, Oxytocin, Maze Learning, Mice, Rats, Calcium-Calmodulin-Dependent Protein Kinase Type 2, CA2 Region, Hippocampal, Antidiuretic Hormone Receptor Antagonists
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
