Cited by 345Opioid Use Disorder TreatmentSubstance Abuse Treatment and OutcomesPain Management and Opioid Use

A review of opioid dependence treatment: Pharmacological and psychosocial interventions to treat opioid addiction

Veilleux, Jennifer C., Colvin, Peter J., Anderson, Jennifer, York, Catherine, Heinz, Adrienne J.·2010·Clinical Psychology Review

Abstract

Opioid dependence is a problem of national concern, especially with dramatically increased rates of abuse and dependence of prescription opioids. The current article provides an up-to-date review of the literature on opioid dependence treatment, with a focus on conclusions drawn by experts in the field (e.g., Cochrane reviews and meta-analyses) and methodologically rigorous studies (e.g., randomized controlled trials). We describe the major classes of drug treatments available, including opioid agonist (e.g., methadone, buprenorphine, LAAM), antagonist (e.g., naltrexone) and non-opioid pharmacotherapies (e.g., alpha2 adrenergic agonists). These treatments are discussed in the context of detoxification and long term treatment options such as abstinence-based and maintenance strategies. We review the state of the literature as to prevention of opioid overdose and discuss the widespread problem of comorbidity among opioid-dependent populations. We also focus prominently on evidence for inclusion of psychosocial approaches in treatment regimens, either as stand-alone or in conjunction with psychopharmacological options.

Integrity signals

Registry

Crossref · 10.1016/j.cpr.2009.10.006

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124 of 124 references verified0 citation errors · 0 not checkable

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Authors
Veilleux, J. C., Colvin, P. J., Anderson, J., York, C., & Heinz, A. J.
Affiliations
University of Illinois Chicago (US)
Corresponding author
Veilleux, Jennifer C.
Venue
Clinical Psychology Review
Publisher
Elsevier BV
Published
2010-03
Volume
30
Issue
2
Pages
155-166
ISSN
0272-7358 (ISSN-L)
OpenAlex
W2038833041
Cited by
336
References
130
Citations by year
2026: 2 · 2025: 12 · 2024: 11 · 2023: 13 · 2022: 21 · 2021: 12 · 2020: 24 · 2019: 62 · 2018: 24 · 2017: 22 · 2016: 18 · 2015: 24 · 2014: 29 · 2013: 22 · 2012: 20
FWCI
1.81
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Psychology Review (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
Keywords
opioid use disorder, opioid dependence treatment, pharmacological interventions, psychosocial interventions, methadone, buprenorphine, LAAM, naltrexone, alpha-2 adrenergic agonists, opioid agonists, opioid antagonists, opioid detoxification, abstinence-based treatment, maintenance therapy, opioid overdose prevention, comorbidities, prescription opioid abuse
MeSH terms
Biofeedback, Psychology, Humans, Narcotic Antagonists, Opioid-Related Disorders, Narcotics, Self-Help Groups, Cognitive Behavioral Therapy, Prevalence, Adrenergic Agents

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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