Catenins: Keeping Cells from Getting Their Signals Crossed

Rho GTPases in cell biology

Etienne-Manneville, S., & Hall, A. (2002) · Nature · doi:10.1038/nature01148 · Cited by 4,201

JUNCTIONAL COMPLEXES IN VARIOUS EPITHELIA

Farquhar, M. G., & Palade, G. E. (1963) · The Journal of Cell Biology · doi:10.1083/jcb.17.2.375 · Cited by 3,635

Convergence of Wnt, ß-Catenin, and Cadherin Pathways

Nelson, W. J., & Nusse, R. (2004) · Science · doi:10.1126/science.1094291 · Cited by 2,515

Multifunctional strands in tight junctions

Tsukita, S., Furuse, M., & Itoh, M. (2001) · Nature Reviews Molecular Cell Biology · doi:10.1038/35067088 · Cited by 2,509

Asymmetric and symmetric stem-cell divisions in development and cancer

Morrison, S. J., & Kimble, J. (2006) · Nature · doi:10.1038/nature04956 · Cited by 1,410

CADHERINS: A MOLECULAR FAMILY IMPORTANT IN SELECTIVE CELL-CELL ADHESION

Takeichi, M. (1990) · Annual Review of Biochemistry · doi:10.1146/annurev.bi.59.070190.001321 · Cited by 1,306

Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion

Vasioukhin, V., Bauer, C., Yin, M., & Fuchs, E. (2000) · Cell · doi:10.1016/s0092-8674(00)81559-7 · Cited by 1,205

De Novo Hair Follicle Morphogenesis and Hair Tumors in Mice Expressing a Truncated β-Catenin in Skin

Gat, U., DasGupta, R., Degenstein, L., & Fuchs, E. (1998) · Cell · doi:10.1016/s0092-8674(00)81631-1 · Cited by 1,089

Deconstructing the Cadherin-Catenin-Actin Complex

Yamada, S., Pokutta, S., Drees, F., Weis, W. I., & Nelson, W. J. (2005) · Cell · doi:10.1016/j.cell.2005.09.020 · Cited by 1,021

Asymmetric cell divisions promote stratification and differentiation of mammalian skin

Lechler, T., & Fuchs, E. (2005) · Nature · doi:10.1038/nature03922 · Cited by 998

α-Catenin Is a Molecular Switch that Binds E-Cadherin-β-Catenin and Regulates Actin-Filament Assembly

Drees, F., Pokutta, S., Yamada, S., Nelson, W. J., & Weis, W. I. (2005) · Cell · doi:10.1016/j.cell.2005.09.021 · Cited by 985

E-cadherin null mutant embryos fail to form a trophectoderm epithelium.

Larue, L., Ohsugi, M., Hirchenhain, J., & Kemler, R. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.17.8263 · Cited by 930

Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex

Fujita, Y., Krause, G., Scheffner, M., Zechner, D., Leddy, H. E. M., Behrens, J., Sommer, T., & Birchmeier, W. (2002) · Nature Cell Biology · doi:10.1038/ncb758 · Cited by 846

The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex.

Gumbiner, B., Stevenson, B., & Grimaldi, A. (1988) · The Journal of cell biology · doi:10.1083/jcb.107.4.1575 · Cited by 799

Regulation of Cadherin Adhesive Activity

Gumbiner, B. M. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.148.3.399 · Cited by 787

Orientation of Asymmetric Stem Cell Division by the APC Tumor Suppressor and Centrosome

Yamashita, Y. M., Jones, D. L., & Fuller, M. T. (2003) · Science · doi:10.1126/science.1087795 · Cited by 738

Alpha 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex.

Rimm, D. L., Koslov, E. R., Kebriaei, P., Cianci, C. D., & Morrow, J. S. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.19.8813 · Cited by 735

A core function for p120-catenin in cadherin turnover

Davis, M. A., Ireton, R. C., & Reynolds, A. B. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200307111 · Cited by 732

Sticky Business

Perez-Moreno, M., Jamora, C., & Fuchs, E. (2003) · Cell · doi:10.1016/s0092-8674(03)00108-9 · Cited by 721

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions

Marambaud, P. (2002) · The EMBO Journal · doi:10.1093/emboj/21.8.1948 · Cited by 685

Ena/VASP Proteins: Regulators of the Actin Cytoskeleton and Cell Migration

Krause, M., Dent, E. W., Bear, J. E., Loureiro, J. J., & Gertler, F. B. (2003) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.19.050103.103356 · Cited by 682

Balancing cell adhesion and Wnt signaling, the key role of β-catenin

Brembeck, F. H., Rosário, M., & Birchmeier, W. (2006) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2005.12.007 · Cited by 668

A common human skin tumour is caused by activating mutations in β-catenin

Chan, E., Gat, U., McNiff, J. M., & Fuchs, E. (1999) · Nature Genetics · doi:10.1038/7747 · Cited by 612

P120 Catenin Regulates the Actin Cytoskeleton via Rho Family Gtpases

Noren, N. K., Liu, B. P., Burridge, K., & Kreft, B. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.3.567 · Cited by 576

The Juxtamembrane Region of the Cadherin Cytoplasmic Tail Supports Lateral Clustering, Adhesive Strengthening, and Interaction with p120ctn

Yap, A. S., Niessen, C. M., & Gumbiner, B. M. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.141.3.779 · Cited by 568

E-cadherin binding prevents β-catenin nuclear localization and β-catenin/LEF-1-mediated transactivation

Orsulic, S., Huber, O., Aberle, H., Arnold, S., & Kemler, R. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.8.1237 · Cited by 534

The p120 catenin partner Kaiso is a DNA methylation-dependent transcriptional repressor

Prokhortchouk, A., Hendrich, B., Jørgensen, H., Ruzov, A., Wilm, M., Georgiev, G., Bird, A., & Prokhortchouk, E. (2001) · Genes & Development · doi:10.1101/gad.198501 · Cited by 533

Recycling of E-Cadherin

Le, T. L., Yap, A. S., & Stow, J. L. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.1.219 · Cited by 532

A novel role for p120 catenin in E-cadherin function

Ireton, R. C., Davis, M. A., van Hengel, J., Mariner, D. J., Barnes, K., Thoreson, M. A., Anastasiadis, P. Z., Matrisian, L., Bundy, L. M., Sealy, L., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200205115 · Cited by 530

Mechanisms of Epithelial Cell–Cell Adhesion and Cell Compaction Revealed by High-resolution Tracking of E-Cadherin– Green Fluorescent Protein

Adams, C. L., Chen, Y.-T., Smith, S. J., & James Nelson, W. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.4.1105 · Cited by 528

Role of IQGAP1, a Target of the Small GTPases Cdc42 and Rac1, in Regulation of E-Cadherin- Mediated Cell-Cell Adhesion

Kuroda, S., Fukata, M., Nakagawa, M., Fujii, K., Nakamura, T., Ookubo, T., Izawa, I., Nagase, T., Nomura, N., Tani, H., et al. (1998) · Science · doi:10.1126/science.281.5378.832 · Cited by 499

Inhibition of RhoA by p120 catenin

Anastasiadis, P. Z., Moon, S. Y., Thoreson, M. A., Mariner, D. J., Crawford, H. C., Zheng, Y., & Reynolds, A. B. (2000) · Nature Cell Biology · doi:10.1038/35023588 · Cited by 472

ROCK and Dia have opposing effects on adherens junctions downstream of Rho

Sahai, E., & Marshall, C. J. (2002) · Nature Cell Biology · doi:10.1038/ncb796 · Cited by 466

Negative Regulation of Fibroblast Motility by Ena/VASP Proteins

Bear, J. E., Loureiro, J. J., Libova, I., Fässler, R., Wehland, J., & Gertler, F. B. (2000) · Cell · doi:10.1016/s0092-8674(00)80884-3 · Cited by 458

Hyperproliferation and Defects in Epithelial Polarity upon Conditional Ablation of α-Catenin in Skin

Vasioukhin, V., Bauer, C., Degenstein, L., Wise, B., & Fuchs, E. (2001) · Cell · doi:10.1016/s0092-8674(01)00246-x · Cited by 435

The p120 catenin family: Complex roles in adhesion, signaling and cancer

Anastasiadis, P. Z., & Reynolds, A. B. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.8.1319 · Cited by 430

Cadherin Engagement Regulates Rho family GTPases

Noren, N. K., Niessen, C. M., Gumbiner, B. M., & Burridge, K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.c100306200 · Cited by 425

Endocytic Traffic in Polarized Epithelial Cells: Role of the Actin and Microtubule Cytoskeleton

Apodaca, G. (2001) · Traffic · doi:10.1034/j.1600-0854.2001.020301.x · Cited by 408

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

Xiao, K., Allison, D. F., Buckley, K. M., Kottke, M. D., Vincent, P. A., Faundez, V., & Kowalczyk, A. P. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200306001 · Cited by 407

Cell-to-cell adherens junction formation and actin filament organization: similarities and differences between non-polarized fibroblasts and polarized epithelial cells

Yonemura, S., Itoh, M., Nagafuchi, A., & Tsukita, S. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.1.127 · Cited by 402

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

Kobielak, A., Pasolli, H. A., & Fuchs, E. (2004) · Nature Cell Biology · doi:10.1038/ncb1075 · Cited by 390

α-catenin: at the junction of intercellular adhesion and actin dynamics

Kobielak, A., & Fuchs, E. (2004) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1433 · Cited by 372

Myosin 2 Is a Key Rho Kinase Target Necessary for the Local Concentration of E-Cadherin at Cell–Cell Contacts

Shewan, A. M., Maddugoda, M., Kraemer, A., Stehbens, S. J., Verma, S., Kovacs, E. M., & Yap, A. S. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-04-0330 · Cited by 371

The Catenin p120 ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor

Daniel, J. M., & Reynolds, A. B. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3614 · Cited by 367

Spatio-Temporal Regulation of Rac1 Localization and Lamellipodia Dynamics during Epithelial Cell-Cell Adhesion

Ehrlich, J. S., Hansen, M. D. H., & Nelson, W. J. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00216-2 · Cited by 358

Actin Cable Dynamics and Rho/Rock Orchestrate a Polarized Cytoskeletal Architecture in the Early Steps of Assembling a Stratified Epithelium

Vaezi, A., Bauer, C., Vasioukhin, V., & Fuchs, E. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00259-9 · Cited by 349

Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene.

Reynolds, A. B., Roesel, D. J., Kanner, S. B., & Parsons, J. T. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.2.629 · Cited by 342

Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours

Celso, C. L., Prowse, D. M., & Watt, F. M. (2004) · Development · doi:10.1242/dev.01052 · Cited by 339

Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions.

Rajasekaran, A. K., Hojo, M., Huima, T., & Rodriguez-Boulan, E. (1996) · The Journal of cell biology · doi:10.1083/jcb.132.3.451 · Cited by 339

Quantitative analysis of cadherin-catenin-actin reorganization during development of cell-cell adhesion.

Adams, C. L., Nelson, W. J., & Smith, S. J. (1996) · The Journal of cell biology · doi:10.1083/jcb.135.6.1899 · Cited by 323

Distinct molecular forms of β-catenin are targeted to adhesive or transcriptional complexes

Gottardi, C. J., & Gumbiner, B. M. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200402153 · Cited by 315

E-cadherin Homophilic Ligation Directly Signals through Rac and Phosphatidylinositol 3-Kinase to Regulate Adhesive Contacts

Kovacs, E. M., Ali, R. G., McCormack, A. J., & Yap, A. S. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109640200 · Cited by 314

Tyrosine phosphorylation and cadherin/catenin function

Daniel, J. M., & Reynolds, A. B. (1997) · BioEssays · doi:10.1002/bies.950191008 · Cited by 313

β-Catenin: A Pivot between Cell Adhesion and Wnt Signalling

Bienz, M. (2005) · Current Biology · doi:10.1016/j.cub.2004.12.058 · Cited by 313

Mammalian tight junctions in the regulation of epithelial differentiation and proliferation

Matter, K., Aijaz, S., Tsapara, A., & Balda, M. S. (2005) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2005.08.003 · Cited by 312

ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly

Palacios, F., Schweitzer, J. K., Boshans, R. L., & D'Souza-Schorey, C. (2002) · Nature Cell Biology · doi:10.1038/ncb881 · Cited by 303

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling.

Orsulic, S., & Peifer, M. (1996) · The Journal of cell biology · doi:10.1083/jcb.134.5.1283 · Cited by 294

Direct cadherin-activated cell signaling

Yap, A. S., & Kovacs, E. M. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200208156 · Cited by 293

Emerging roles for p120-catenin in cell adhesion and cancer

Reynolds, A. B., & Roczniak-Ferguson, A. (2004) · Oncogene · doi:10.1038/sj.onc.1208161 · Cited by 287

An essential role for ARF6-regulated membrane traffic in adherens junction turnover and epithelial cell migration

Palacios, F. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4973 · Cited by 284

p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell-cell contact formation and regulation of cell locomotion

Grosheva, I., Shtutman, M., Elbaum, M., & Bershadsky, A. D. (2001) · Journal of Cell Science · doi:10.1242/jcs.114.4.695 · Cited by 282

p120-Catenin Regulates Clathrin-dependent Endocytosis of VE-Cadherin

Xiao, K., Garner, J., Buckley, K. M., Vincent, P. A., Chiasson, C. M., Dejana, E., Faundez, V., & Kowalczyk, A. P. (2005) · Molecular Biology of the Cell · doi:10.1091/mbc.e05-05-0440 · Cited by 282

Regulation of Rho GTPases by p120-catenin

Anastasiadis, P. Z., & Reynolds, A. B. (2001) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(00)00258-1 · Cited by 278

Cross-Talk between Adherens Junctions and Desmosomes Depends on Plakoglobin

Lewis, J. E., Wahl, J. K., Sass, K. M., Jensen, P. J., Johnson, K. R., & Wheelock, M. J. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.136.4.919 · Cited by 276

Two Cell Adhesion Molecules, Nectin and Cadherin, Interact through Their Cytoplasmic Domain–Associated Proteins

Tachibana, K., Nakanishi, H., Mandai, K., Ozaki, K., Ikeda, W., Yamamoto, Y., Nagafuchi, A., Tsukita, S., & Takai, Y. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.150.5.1161 · Cited by 272

Regulation of cell–cell junctions by the cytoskeleton

Mège, R.-M., Gavard, J., & Lambert, M. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.08.004 · Cited by 269

p120-Catenin Mediates Inflammatory Responses in the Skin

Perez-Moreno, M., Davis, M. A., Wong, E., Pasolli, H. A., Reynolds, A. B., & Fuchs, E. (2006) · Cell · doi:10.1016/j.cell.2005.11.043 · Cited by 264

Transient activation of β-catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice

Van Mater, D., Kolligs, F. T., Dlugosz, A. A., & Fearon, E. R. (2003) · Genes & Development · doi:10.1101/gad.1076103 · Cited by 263

p120 catenin associates with kinesin and facilitates the transport of cadherin–catenin complexes to intercellular junctions

Chen, X., Kojima, S.-I., Borisy, G. G., & Green, K. J. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200305137 · Cited by 259

αE-Catenin Controls Cerebral Cortical Size by Regulating the Hedgehog Signaling Pathway

Lien, W., Klezovitch, O., Fernandez, T. E., Delrow, J. J., & Vasioukhin, V. I. (2006) · Science · doi:10.1126/science.1121449 · Cited by 251

Biochemical and Structural Definition of the l-Afadin- and Actin-binding Sites of α-Catenin

Pokutta, S., Drees, F., Takai, Y., Nelson, W. J., & Weis, W. I. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201463200 · Cited by 245

Kaiso/p120-Catenin and TCF/β-Catenin Complexes Coordinately Regulate Canonical Wnt Gene Targets

Park, J.-I., Kim, S. W., Lyons, J. P., Ji, H., Nguyen, T. T., Cho, K., Barton, M. C., Deroo, T., Vleminckx, K., & McCrea, P. D. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.04.010 · Cited by 234

Vezatin, a novel transmembrane protein, bridges myosin VIIA to the cadherin-catenins complex

Kussel-Andermann, P. (2000) · The EMBO Journal · doi:10.1093/emboj/19.22.6020 · Cited by 230

An α- E-catenin gene trap mutation defines its function in preimplantation development

Torres, M., Stoykova, A., Huber, O., Chowdhury, K., Bonaldo, P., Mansouri, A., Butz, S., Kemler, R., & Gruss, P. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.3.901 · Cited by 216

Cadherin-mediated cell–cell adhesion: sticking together as a family

Patel, S. D., Chen, C. P., Bahna, F., Honig, B., & Shapiro, L. (2003) · Current Opinion in Structural Biology · doi:10.1016/j.sbi.2003.10.007 · Cited by 215

Disassembling adherens junctions: breaking up is hard to do

D'Souza-Schorey, C. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2004.11.002 · Cited by 210

p120 Catenin Regulates Dendritic Spine and Synapse Development through Rho-Family GTPases and Cadherins

Elia, L. P., Yamamoto, M., Zang, K., & Reichardt, L. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.05.018 · Cited by 206

RAC1 Regulates Adherens Junctions through Endocytosis of E-Cadherin

Akhtar, N., & Hotchin, N. A. (2001) · Molecular Biology of the Cell · doi:10.1091/mbc.12.4.847 · Cited by 200

Regulation of desmosome assembly and adhesion

Yin, T., & Green, K. J. (2004) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.09.005 · Cited by 199

Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial priming

Raich, W. B., Agbunag, C., & Hardin, J. (1999) · Current Biology · doi:10.1016/s0960-9822(00)80015-9 · Cited by 199

Recycling of E-Cadherin: A Potential Mechanism for Regulating Cadherin Dynamics

Le, T. L. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.999.219 · Cited by 196

Blocked Acinar Development, E-Cadherin Reduction, and Intraepithelial Neoplasia upon Ablation of p120-Catenin in the Mouse Salivary Gland

Davis, M. A., & Reynolds, A. B. (2006) · Developmental Cell · doi:10.1016/j.devcel.2005.12.004 · Cited by 188

Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex

Baki, L., Marambaud, P., Efthimiopoulos, S., Georgakopoulos, A., Wen, P., Cui, W., Shioi, J., Koo, E., Ozawa, M., Friedrich, V. L., et al. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.041603398 · Cited by 185

Rho1 interacts with p120ctn and α-catenin, and regulates cadherin-based adherens junction components in Drosophila

Magie, C. R., Pinto-Santini, D., & Parkhurst, S. M. (2002) · Development · doi:10.1242/dev.129.16.3771 · Cited by 182

Molecular Cloning of the Human p120ctnCatenin Gene (CTNND1): Expression of Multiple Alternatively Spliced Isoforms

Keirsebilck, A., Bonné, S., Staes, K., van Hengel, J., Nollet, F., Reynolds, A. B., & Roy, F. M. V. (1998) · Genomics · doi:10.1006/geno.1998.5325 · Cited by 176

Plakophilins: Multifunctional proteins or just regulators of desmosomal adhesion?

Hatzfeld, M. (2007) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2006.04.009 · Cited by 174

Cadherin Function Is Required for Human Keratinocytes to Assemble Desmosomes and Stratify in Response to Calcium

Lewis, J. E., Jensen, P. J., & Wheelock, M. J. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12382690 · Cited by 173

Csk-Deficient Boundary Cells Are Eliminated from Normal Drosophila Epithelia by Exclusion, Migration, and Apoptosis

Vidal, M., Larson, D. E., & Cagan, R. L. (2006) · Developmental Cell · doi:10.1016/j.devcel.2005.11.007 · Cited by 173

Synaptic contact dynamics controlled by cadherin and catenins

Takeichi, M., & Abe, K. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.02.002 · Cited by 172

Non-canonical Wnt signals are modulated by the Kaiso transcriptional repressor and p120-catenin

Kim, S. W., Park, J.-I., Spring, C. M., Sater, A. K., Ji, H., Otchere, A. A., Daniel, J. M., & McCrea, P. D. (2004) · Nature Cell Biology · doi:10.1038/ncb1191 · Cited by 171

Kaiso-Deficient Mice Show Resistance to Intestinal Cancer

Prokhortchouk, A., Sansom, O., Selfridge, J., Caballero, I. M., Salozhin, S., Aithozhina, D., Cerchietti, L., Meng, F. G., Augenlicht, L. H., Mariadason, J. M., et al. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.1.199-208.2006 · Cited by 169

The p120 family of cell adhesion molecules

Hatzfeld, M. (2005) · European Journal of Cell Biology · doi:10.1016/j.ejcb.2004.12.016 · Cited by 153

Regulation of Endocytosis, Nuclear Translocation, and Signaling of Fibroblast Growth Factor Receptor 1 by E-Cadherin

Bryant, D. M., Wylie, F. G., & Stow, J. L. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-09-0845 · Cited by 148

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

Gavard, J., Lambert, M., Grosheva, I., Marthiens, V., Irinopoulou, T., Riou, J., Bershadsky, A. D., & Mège, R. (2003) · Journal of Cell Science · doi:10.1242/jcs.00857 · Cited by 137

The Caenorhabditis elegans p120 catenin homologue, JAC-1, modulates cadherin–catenin function during epidermal morphogenesis

Pettitt, J., Cox, E. A., Broadbent, I. D., Flett, A., & Hardin, J. D. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200212136 · Cited by 137

Regulation of cadherin stability and turnover by p120ctn: implications in disease and cancer

Reynolds, A. B., & Carnahan, R. H. (2004) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2004.09.003 · Cited by 130

A role for Kaiso–p120ctn complexes in cancer?

Roy, F. M. V., & McCrea, P. D. (2005) · Nature reviews. Cancer · doi:10.1038/nrc1752 · Cited by 129

Drosophila p120catenin plays a supporting role in cell adhesion but is not an essential adherens junction component

Myster, S. H., Cavallo, R., Anderson, C. T., Fox, D. T., & Peifer, M. A. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211083 · Cited by 128

Links between α-catenin, NF-κB, and squamous cell carcinoma in skin

Kobielak, A., & Fuchs, E. V. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510422103 · Cited by 124

Drosophila E-Cadherin Regulates the Orientation of Asymmetric Cell Division in the Sensory Organ Lineage

Borgne, R. L., Bellaı̈che, Y., & Schweisguth, F. (2002) · Current Biology · doi:10.1016/s0960-9822(01)00648-0 · Cited by 121

Deletion in Catna2, encoding αN-catenin, causes cerebellar and hippocampal lamination defects and impaired startle modulation

Park, C., Falls, W. A., Finger, J. H., Longo-Guess, C. M., & Ackerman, S. L. (2002) · Nature Genetics · doi:10.1038/ng908 · Cited by 118

Regulation of the Rapsyn Promoter by Kaiso and δ-Catenin

Rodova, M., Kelly, K. F., VanSaun, M. N., Daniel, J. M., & Werle, M. J. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.16.7188-7196.2004 · Cited by 112

Tyrosine Phosphorylation of Plakoglobin Causes Contrary Effects on Its Association with Desmosomes and Adherens Junction Components and Modulates β-Catenin-Mediated Transcription

Miravet, S., Piedra, J. A., Castaño, J., Raurell, I., Francı́, C., Duñach, M., & de Herreros, A. G. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.20.7391-7402.2003 · Cited by 111

Vertebrate development requires ARVCF and p120 catenins and their interplay with RhoA and Rac

Fang, X., Ji, H. L., Kim, S.-W., Park, J., Vaught, T. G., Anastasiadis, P. Z., Ciesiolka, M., & McCrea, P. D. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307109 · Cited by 103

Frodo Links Dishevelled to the p120-Catenin/Kaiso Pathway: Distinct Catenin Subfamilies Promote Wnt Signals

Park, J., Ji, H. L., Jun, S., Gu, D., Hikasa, H., Li, L., Sokol, S. Y., & McCrea, P. D. (2006) · Developmental Cell · doi:10.1016/j.devcel.2006.09.022 · Cited by 99

Transformation-Specific Tyrosine Phosphorylation of a Novel Cellular Protein in Chicken Cells Expressing Oncogenic Variants of the Avian Cellular src Gene

Reynolds, A. B., Roesel, D. J., Kanner, S. B., & Parsons, J. T. (1989) · Molecular and Cellular Biology · doi:10.1128/mcb.9.2.629-638.1989 · Cited by 97

DrosophilaRhoA regulates the cytoskeleton and cell-cell adhesion in the developing epidermis

Bloor, J. W., & Kiehart, D. P. (2002) · Development · doi:10.1242/dev.129.13.3173 · Cited by 96

Binding site for p120/δ-catenin is not required for Drosophila E-cadherin function in vivo

Pacquelet, A., Lin, L., & Rørth, P. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200207160 · Cited by 88

α-Catenin Can Form Asymmetric Homodimeric Complexes and/or Heterodimeric Complexes with ॆ-Catenin

Koslov, E. R., Maupin, P., Pradhan, D., Morrow, J. S., & Rimm, D. L. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.43.27301 · Cited by 87

Cadherin–catenin proteins in vertebrate development

Lien, W., Klezovitch, O., & Vasioukhin, V. I. (2006) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2006.07.001 · Cited by 81

α-Catenin Binds Directly to Spectrin and Facilitates Spectrin-Membrane Assembly in Vivo

Pradhan, D., Lombardo, C. R., Roe, S., Rimm, D. L., & Morrow, J. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m009259200 · Cited by 71

p120 Catenin Associates with Microtubules

Franz, C. M., & Ridley, A. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312812200 · Cited by 71

Expression and Nuclear Location of the Transcriptional Repressor Kaiso Is Regulated by the Tumor Microenvironment

Soubry, A., van Hengel, J., Parthoens, E., Colpaert, C., Marck, E. V., Waltregny, D., Reynolds, A. B., & Roy, F. M. V. (2005) · Cancer Research · doi:10.1158/0008-5472.can-04-2020 · Cited by 68

Expression of inappropriate cadherins by epithelial tumor cells promotes endocytosis and degradation of E-cadherin via competition for p120ctn

Maeda, M., Johnson, E., Mandal, S., LAWSON, K. R., Keim, S., Svoboda, R. A., Caplan, S., Wahl, J. K., Wheelock, M. J., & Johnson, K. R. (2006) · Oncogene · doi:10.1038/sj.onc.1209396 · Cited by 60

Antagonism of Cell Adhesion by an α-Catenin Mutant, and of the Wnt-signaling Pathway by α-Catenin in Xenopus Embryos

Sehgal, R. N. M., Gumbiner, B. M., & Reichardt, L. F. (1997) · The Journal of Cell Biology · doi:10.1083/jcb.139.4.1033 · Cited by 58

Rho1 regulatesDrosophilaadherens junctions independently of p120ctn

Fox, D. T., Homem, C. C. F., Myster, S. H., Wang, F., Bain, E. E., & Peifer, M. A. (2005) · Development · doi:10.1242/dev.02056 · Cited by 56

Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120 in Xenopus laevis

Kim, S. W., Fang, X., Ji, H. L., Paulson, A. F., Daniel, J. M., Ciesiolka, M., Roy, F. M. V., & McCrea, P. D. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m109508200 · Cited by 52

p120 catenin is required for morphogenetic movements involved in the formation of the eyes and the craniofacial skeleton in Xenopus

Ciesiolka, M., Delvaeye, M., Imschoot, G. V., Verschuere, V., McCrea, P. D., Roy, F. M. V., & Vleminckx, K. (2004) · Journal of Cell Science · doi:10.1242/jcs.01298 · Cited by 52

Intestinal barrier function: molecular regulation and disease pathogenesis

Groschwitz, K. R., & Hogan, S. P. (2009) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2009.05.038 · Cited by 1,775

The Hippo pathway: regulators and regulations.

Yu, F.-X., & Guan, K.-L. (2013) · Genes & Development · doi:10.1101/gad.210773.112 · Cited by 1,231

Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components1,2

Ulluwishewa, D., Anderson, R. C., McNabb, W. C., Moughan, P. J., Wells, J. M., & Roy, N. C. (2011) · The Journal of Nutrition · doi:10.3945/jn.110.135657 · Cited by 1,177

Adherens junctions: from molecules to morphogenesis

Harris, T. J. C., & Tepass, U. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2927 · Cited by 990

Linking actin dynamics and gene transcription to drive cellular motile functions

Olson, E. N., & Nordheim, A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2890 · Cited by 958