Obesity and diabetes as accelerators of functional decline: Can lifestyle interventions maintain functional status in high risk older adults?
Open accessAbstract
Obesity and diabetes are known risk factors for the development of physical disability among older adults. With the number of seniors with these conditions rising worldwide, the prevention and treatment of physical disability in these persons have become a major public health challenge. Sarcopenia, the progressive loss of muscle mass and strength, has been identified as a common pathway associated with the initial onset and progression of physical disability among older adults. A growing body of evidence suggests that metabolic dysregulation associated with obesity and diabetes accelerates the progression of sarcopenia, and subsequently functional decline in older adults. The focus of this brief review is on the contributions of obesity and diabetes in accelerating sarcopenia and functional decline among older adults. We also briefly discuss the underexplored interaction between obesity and diabetes that may further accelerate sarcopenia and place obese older adults with diabetes at particularly high risk of disability. Finally, we review findings from studies that have specifically tested the efficacy of lifestyle-based interventions in maintaining the functional status of older persons with obesity and/or diabetes.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The majority of published RT studies in older adults (≥65 y of age) have been conducted in normal-weight or nonobese individuals.
“The majority of published RT studies in older adults ($65 y of age) have been conducted in normal-weight or nonobese individuals (8,24).”
From Effects of resistance training with and without caloric restriction on physical function and mobility in overweight and obese older adults: a randomized controlled trial (2015) · cites this paper as [24]
In “Effects of Lifestyle Interventions on Physical Function in Obese Older Adults” (page unavailable), the review says few studies have examined exercise interventions alone in obese older adults. That supports the general point that this population is understudied, but it does not establish that a majority of published resistance-training studies in adults aged 65 or older enrolled normal-weight or nonobese participants. (LLM, conf=0.78)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin
(2002) · New England Journal of Medicine · doi:10.1056/nejmoa012512 · Cited by 19,011 · see citing works
Prevalence and Trends in Obesity Among US Adults, 1999-2008
Flegal, K. M. (2010) · JAMA · doi:10.1001/jama.2009.2014 · Cited by 7,580 · see citing works
Xu, H., Barnes, G. T., Yang, Q., Tan, G., Yang, D., Chou, C. J., Sole, J., Nichols, A., Ross, J. S., Tartaglia, L. A., et al. (2003) · Journal of Clinical Investigation · doi:10.1172/jci200319451 · Cited by 6,760 · see citing works
Exercise and Physical Activity for Older Adults
Chodzko-Zajko, W. J., Proctor, D. N., Fiatarone Singh, M. A., Minson, C. T., Nigg, C. R., Salem, G. J., & Skinner, J. S. (2009) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0b013e3181a0c95c · Cited by 5,153 · see citing works
Gait speed and survival in older adults.
Studenski, S. (2011) · JAMA · doi:10.1001/jama.2010.1923 · Cited by 4,558 · see citing works
Janssen, I., Heymsfield, S. B., & Ross, R. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50216.x · Cited by 3,139 · cited 3× · see citing works
“Importantly, previous studies have found that risk of functional impairment and disability in older adults dramatically increases if muscle loss progresses to the point where relative muscle mass declines below 30% of the mean for young adults (Janssen et al., 2002).”
The healthcare costs of sarcopenia in the United States
Janssen, I., Shepard, D. S., Katzmarzyk, P. T., & Roubenoff, R. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52014.x · Cited by 1,546 · see citing works
Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes
The Look AHEAD Research Group (2007) · Diabetes Care · doi:10.2337/dc07-0048 · Cited by 1,522 · see citing works
Longitudinal study of muscle strength, quality, and adipose tissue infiltration
Delmonico, M. J., Harris, T. B., Visser, M., Park, S. W., Conroy, M. B., Velasquez-Mieyer, P., Boudreau, R., Manini, T. M., Nevitt, M., Newman, A. B., et al. (2009) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.2009.28047 · Cited by 1,446 · see citing works
Boyle, J. P., Thompson, T. J., Gregg, E. W., Barker, L. E., & Williamson, D. F. (2010) · Population Health Metrics · doi:10.1186/1478-7954-8-29 · Cited by 1,309 · see citing works
Attenuation of skeletal muscle and strength in the elderly: the Health ABC Study
Goodpaster, B. H., Carlson, C. L., Visser, M., Kelley, D. E., Scherzinger, A., Harris, T. B., Stamm, E., & Newman, A. B. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.90.6.2157 · Cited by 1,226 · see citing works
Weight loss, exercise, or both and physical function in obese older adults
Villareal, D. T., Chode, S., Parimi, N., Sinacore, D. R., Hilton, T., Armamento-Villareal, R., Napoli, N., Qualls, C., & Shah, K. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1008234 · Cited by 1,096 · see citing works
Messier, S. P., Loeser, R. F., Miller, G. D., Morgan, T. M., Rejeski, W. J., Sevick, M. A., Ettinger, W. H., Pahor, M., & Williamson, J. D. (2004) · Arthritis & Rheumatism · doi:10.1002/art.20256 · Cited by 1,065 · see citing works
Sarcopenic Obesity Predicts Instrumental Activities of Daily Living Disability in the Elderly
Baumgartner, R. N., Wayne, S. J., Waters, D. L., Janssen, I., Gallagher, D., & Morley, J. E. (2004) · Obesity Research · doi:10.1038/oby.2004.250 · Cited by 937 · see citing works
Castaneda, C., Layne, J. E., Munoz-Orians, L., Gordon, P. L., Walsmith, J., Foldvari, M., Roubenoff, R., Tucker, K. L., & Nelson, M. E. (2002) · Diabetes Care · doi:10.2337/diacare.25.12.2335 · Cited by 844 · see citing works
Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 Diabetes
Park, S. W., Goodpaster, B. H., Lee, J. S., Kuller, L. H., Boudreau, R., de Rekeneire, N., Harris, T. B., Kritchevsky, S., Tylavsky, F. A., Nevitt, M., et al. (2009) · Diabetes Care · doi:10.2337/dc09-0264 · Cited by 778 · see citing works
Accelerated Loss of Skeletal Muscle Strength in Older Adults With Type 2 Diabetes
Park, S. W., Goodpaster, B. H., Strotmeyer, E. S., Kuller, L. H., Broudeau, R., Kammerer, C., de Rekeneire, N., Harris, T. B., Schwartz, A. V., Tylavsky, F. A., et al. (2007) · Diabetes Care · doi:10.2337/dc06-2537 · Cited by 766 · see citing works
Decreased Muscle Strength and Quality in Older Adults With Type 2 Diabetes
Park, S. W., Goodpaster, B. H., Strotmeyer, E. S., de Rekeneire, N., Harris, T. B., Schwartz, A. V., Tylavsky, F. A., & Newman, A. B. (2006) · Diabetes · doi:10.2337/db05-1183 · Cited by 751 · see citing works
Afilalo, J., Eisenberg, M. J., Morin, J.-F., Bergman, H., Monette, J., Noiseux, N., Perrault, L. P., Alexander, K. P., Langlois, Y., Dendukuri, N., et al. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.06.039 · Cited by 746 · see citing works
An Objective Measure of Physical Function of Elderly Outpatients
Reuben, D. B., & Siu, A. L. (1990) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1990.tb01373.x · Cited by 722 · see citing works
Oxidative Stress, Molecular Inflammation and Sarcopenia
Meng, S.-J., & Yu, L.-J. (2010) · International Journal of Molecular Sciences · doi:10.3390/ijms11041509 · Cited by 637 · see citing works
Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes
Kim, T. N., Park, M. S., Yang, S. J., Yoo, H. J., Kang, H. J., Song, W., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2010) · Diabetes Care · doi:10.2337/dc09-2310 · Cited by 585 · see citing works
A Longitudinal Study of Functional Change and Mortality in the United States
Mantón, K. G. (1988) · Journal of Gerontology · doi:10.1093/geronj/43.5.s153 · Cited by 512 · see citing works
Physical Activity, Falls, and Fractures Among Older Adults: A Review of the Epidemiologic Evidence
Gregg, E. W., Pereira, M. A., & Caspersen, C. J. (2000) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2000.tb06884.x · Cited by 507 · see citing works
Physical frailty and body composition in obese elderly men and women
Villareal, D. T., Banks, M., Siener, C., Sinacore, D. R., & Klein, S. (2004) · Obesity Research · doi:10.1038/oby.2004.111 · Cited by 459 · see citing works
A prospective study of long-term care institutionalization among the aged.
Branch, L. G., & Jette, A. M. (1982) · American Journal of Public Health · doi:10.2105/ajph.72.12.1373 · Cited by 440 · see citing works
Psychological and metabolic stress: A recipe for accelerated cellular aging?
Epel, E. S. (2009) · HORMONES · doi:10.14310/horm.2002.1217 · Cited by 422 · see citing works
Penninx, B. W. J. H., Ferrucci, L., Leveille, S. G., Rantanen, T., Pahor, M., & Guralnik, J. M. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.11.m691 · Cited by 403 · see citing works
The Framingham Disability Study: II. Physical disability among the aging.
Jette, A. M., & Branch, L. G. (1981) · American Journal of Public Health · doi:10.2105/ajph.71.11.1211 · Cited by 393 · see citing works
Obesity and mobility disability in the older adult
Vincent, H. K., Vincent, K. R., & Lamb, K. M. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00703.x · Cited by 382 · see citing works
Anker, S. D. (1999) · European Heart Journal · doi:10.1053/euhj.1998.1446 · Cited by 374 · see citing works
Functional transitions among the elderly: patterns, predictors, and related hospital use.
Mor, V., Wilcox, V. L., Rakowski, W., & Hiris, J. (1994) · American Journal of Public Health · doi:10.2105/ajph.84.8.1274 · Cited by 347 · see citing works
Association of Diabetes, Comorbidities, and A1C With Functional Disability in Older Adults
Kalyani, R. R., Saudek, C. D., Brancati, F. L., & Selvin, E. (2010) · Diabetes Care · doi:10.2337/dc09-1597 · Cited by 336 · see citing works
Reduced physical activity increases intermuscular adipose tissue in healthy young adults
Manini, T. M., Clark, B. C., Nalls, M. A., Goodpaster, B. H., Ploutz-Snyder, L. L., & Harris, T. B. (2007) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/85.2.377 · Cited by 332 · see citing works
The gait and balance of patients with diabetes can be improved: a randomised controlled trial
Allet, L., Armand, S., de Bie, R. A., Golay, A., Monnin, D., Aminian, K., Staal, J. B., & de Bruin, E. D. (2009) · Diabetologia · doi:10.1007/s00125-009-1592-4 · Cited by 306 · see citing works
Effect of weight loss and exercise on frailty in obese older adults
Villareal, D. T., Banks, M., Sinacore, D. R., Siener, C., & Klein, S. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.8.860 · Cited by 302 · see citing works
Lifestyle change and mobility in obese adults with type 2 diabetes
Rejeski, W. J., Ip, E. H., Bertoni, A. G., Bray, G. A., Evans, G., Gregg, E. W., & Zhang, Q. (2012) · New England Journal of Medicine · doi:10.1056/nejmoa1110294 · Cited by 301 · see citing works
Davidson, L. E., Hudson, R., Kilpatrick, K., Kuk, J. L., McMillan, K., Janiszewski, P. M., Lee, S., Lam, M., & Ross, R. (2009) · Archives of Internal Medicine · doi:10.1001/archinternmed.2008.558 · Cited by 297 · see citing works
Buford, T. W., Anton, S. D., Judge, A. R., Marzetti, E., Wohlgemuth, S. E., Carter, C. S., Leeuwenburgh, C., Pahor, M., & Manini, T. M. (2010) · Ageing Research Reviews · doi:10.1016/j.arr.2010.04.004 · Cited by 295 · see citing works
Self-citationRole of muscle mass and muscle quality in the association between diabetes and gait speed
Volpato, S., Bianchi, L., Lauretani, F., Lauretani, F., Bandinelli, S., Guralnik, J. M., Zuliani, G., & Ferrucci, L. (2012) · Diabetes Care · doi:10.2337/dc11-2202 · Cited by 294 · see citing works
1 Physical Disability in Older Americans
Guralnik, J. M., & Simonsick, E. M. (1993) · Journal of Gerontology · doi:10.1093/geronj/48.special_issue.3 · Cited by 274 · see citing works
Koster, A., Ding, J., Stenholm, S., Caserotti, P., Houston, D. K., Nicklas, B. J., You, T., Lee, J. S., Visser, M., Newman, A. B., et al. (2011) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/glr070 · Cited by 274 · see citing works
The Obesity Pandemic: Where Have We Been and Where Are We Going?
Roth, J., Qiang, X., Marbán, S. L., Redelt, H., & Lowell, B. (2004) · Obesity Research · doi:10.1038/oby.2004.273 · Cited by 264 · see citing works
Visser, M., Harris, T. B., Langlois, J. A., Hannan, M. T., Roubenoff, R., Felson, D. T., Wilson, P. W. F., & Kiel, D. P. (1998) · The Journals of Gerontology Series A · doi:10.1093/gerona/53a.3.m214 · Cited by 259 · see citing works
Stenholm, S., Alley, D., Bandinelli, S., Griswold, M. E., Koskinen, S., Rantanen, T., Guralnik, J. M., & Ferrucci, L. (2009) · International Journal of Obesity · doi:10.1038/ijo.2009.62 · Cited by 248 · see citing works
Miller, G. D., Nicklas, B. J., Davis, C., Loeser, R. F., Lenchik, L., & Messier, S. P. (2006) · Obesity · doi:10.1038/oby.2006.139 · Cited by 247 · see citing works
Promoting and prescribing exercise for the elderly.
Nied, R. J., & Franklin, B. A. (2002) · PubMed · Cited by 244 · see citing works
Summary health statistics for U.S. adults: National Health Interview Survey, 2001.
Lucas, J. W., Schiller, J. S., & Benson, V. (2004) · PubMed · Cited by 227 · see citing works
Volpato, S., Blaum, C. S., Resnick, H. E., Ferrucci, L., Fried, L. P., & Guralnik, J. M. (2002) · Diabetes Care · doi:10.2337/diacare.25.4.678 · Cited by 217 · see citing works
Predictors of weight change in men: Results from The Health Professionals Follow-Up Study
Coakley, E., Rimm, E. B., Colditz, G. A., Kawachi, I. I., & Willett, W. C. (1998) · International Journal of Obesity · doi:10.1038/sj.ijo.0800549 · Cited by 210 · see citing works
Association of Muscle Strength with Functional Status of Elderly People
HYATT, R. H., Whitelaw, M. N., Bhat, A., SCOTT, S., & Maxwell, J. D. (1990) · Age and Ageing · doi:10.1093/ageing/19.5.330 · Cited by 204 · see citing works
Weighty Concerns: The Growing Prevalence of Obesity among Older Adults
Houston, D. K., Nicklas, B. J., & Zizza, C. A. (2009) · Journal of the American Dietetic Association · doi:10.1016/j.jada.2009.08.014 · Cited by 201 · see citing works
Nicklas, B. J., Wang, X., You, T., Lyles, M. F., Demons, J. L., Easter, L. H., Berry, M. J., Lenchik, L., & Carr, J. J. (2009) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.2008.26938 · Cited by 193 · see citing works
The aging musculoskeletal system and obesity-related considerations with exercise
Vincent, H. K., Raiser, S. N., & Vincent, K. R. (2012) · Ageing Research Reviews · doi:10.1016/j.arr.2012.03.002 · Cited by 186 · see citing works
Diabetes, Sarcopenia, and Frailty
Morley, J. E. (2008) · Clinics in Geriatric Medicine · doi:10.1016/j.cger.2008.03.004 · Cited by 186 · see citing works
The Cardiometabolic Syndrome and Sarcopenic Obesity in Older Persons
Dominguez, L. J., & Barbagallo, M. (2007) · Journal of the CardioMetabolic Syndrome · doi:10.1111/j.1559-4564.2007.06673.x · Cited by 185 · see citing works
Obesity, Physical Function, and Mortality in Older Adults
Lang, I., Llewellyn, D. J., Alexander, K., & Melzer, D. R. (2008) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2008.01813.x · Cited by 180 · see citing works
Impact of diabetes on physical function in older people
Sinclair, A. J., Conroy, S. P., & Bayer, A. J. (2008) · Diabetes Care · doi:10.2337/dc07-1784 · Cited by 179 · see citing works
Dynapenic-Obesity and Physical Function in Older Adults
B̀ouchard, D. R., & Janssen, I. (2009) · The Journals of Gerontology Series A · doi:10.1093/gerona/glp159 · Cited by 178 · see citing works
Song, C. H., PETROFSKY, J. S., Lee, S., Lee, K. J., & Yim, J. (2011) · Diabetes Technology & Therapeutics · doi:10.1089/dia.2011.0036 · Cited by 157 · see citing works
Diabetes Is Associated With Subclinical Functional Limitation in Nondisabled Older Individuals
de Rekeneire, N., Resnick, H. E., Schwartz, A. V., Shorr, R. I., Kuller, L. H., Simonsick, E. M., Vellas, B. J., & Harris, T. B. (2003) · Diabetes Care · doi:10.2337/diacare.26.12.3257 · Cited by 156 · see citing works
Signaling pathways weigh in on decisions to make or break skeletal muscle
Guttridge, D. C. (2004) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/01.mco.0000134364.61406.26 · Cited by 149 · see citing works
Dietary Weight Loss and Exercise Effects on Insulin Resistance in Postmenopausal Women
Mason, C. E., Foster‐Schubert, K. E., Imayama, I., Kong, A., Xiao, L., Bain, C. E., Campbell, K. L., Wang, C.-Y., Duggan, C. R., Ulrich, C. M., et al. (2011) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2011.06.042 · Cited by 142 · see citing works
Fagot‐Campagna, A., Bourdel‐Marchasson, I., & Simon, D. (2005) · Diabetes & Metabolism · doi:10.1016/s1262-3636(05)73650-8 · Cited by 132 · see citing works
Santanasto, A. J., Glynn, N. W., Newman, M. A., Taylor, C. A., Brooks, M. M., Goodpaster, B. H., & Newman, A. B. (2011) · Journal of Obesity · doi:10.1155/2011/516576 · Cited by 132 · see citing works
Prevalence of Self-Reported Physically Active Adults—United States, 2007
(2009) · JAMA · doi:10.1001/jama.2009.246 · Cited by 132 · see citing works
Adult Obesity and the Burden of Disability throughout Life
Peeters, A., Bonneux, L. G. A., Nusselder, W. J., Laet, C. E. D. H. D., & Barendregt, J. J. (2004) · Obesity Research · doi:10.1038/oby.2004.143 · Cited by 131 · see citing works
Avila, J. J., Gutierres, J. A., Sheehy, M. E., Lofgren, I. E., & Delmonico, M. J. (2010) · European Journal of Applied Physiology · doi:10.1007/s00421-010-1387-9 · Cited by 128 · see citing works
Foy, C. G., Lewis, C. E., Hairston, K. G., Miller, G. D., Lang, W., Jakicic, J. M., Rejeski, W. J., Ribisl, P. M., Walkup, M. P., & Wagenknecht, L. E. (2010) · Obesity · doi:10.1038/oby.2010.120 · Cited by 122 · see citing works
Obesity, intentional weight loss and physical disability in older adults
Rejeski, W. J., Marsh, A. P., Chmelo, E., & Rejeski, J. J. (2010) · Obesity Reviews · doi:10.1111/j.1467-789x.2009.00679.x · Cited by 120 · see citing works
Daly, R. M., Dunstan, D. W., Owen, N., Jolley, D., Shaw, J. E., & Zimmet, P. Z. (2005) · Osteoporosis International · doi:10.1007/s00198-005-1906-4 · Cited by 118 · see citing works
Bouchard, D. R., Soucy, L., Sénéchal, M., Dionne, I. J., & Brochu, M. (2009) · Menopause · doi:10.1097/gme.0b013e31817dacf7 · Cited by 117 · see citing works
Summary health statistics for U.S. adults: National Health Interview Survey, 2000.
Pleis, J. R., Schiller, J. S., & Benson, V. (2003) · PubMed · Cited by 113 · see citing works
Progression of Lower-Extremity Disability in Older Women With Diabetes
Volpato, S., Ferrucci, L., Blaum, C. S., Ostir, G. V., Cappola, A. R., Fried, L. P., Fellin, R., & Guralnik, J. M. (2003) · Diabetes Care · doi:10.2337/diacare.26.1.70 · Cited by 108 · see citing works
Type 2 Diabetes and Risk for Functional Decline and Disability in Older Persons
Volpato, S., Maraldi, C., & Fellin, R. (2010) · Current Diabetes Reviews · doi:10.2174/157339910791162961 · Cited by 107 · see citing works
Ability of Fat and Fat-Free Mass Percentages to Predict Functional Disability in Older Men and Women
Broadwin, J., Goodman‐Gruen, D., & Slymen, D. (2001) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2001.t01-1-49273.x · Cited by 103 · see citing works
The case for low carbohydrate diets in diabetes management
Arora, S. K., & McFarlane, S. I. (2005) · Nutrition & Metabolism · doi:10.1186/1743-7075-2-16 · Cited by 102 · see citing works
Geirsdóttir, Ó. G., Arnarson, A., Briem, K., Ramel, A., Jónsson, P. V., & Þórsdóttir, I. (2012) · The Journals of Gerontology Series A · doi:10.1093/gerona/gls096 · Cited by 101 · see citing works
Weight Loss Intervention for Obese Older Women: Improvements in Performance and Function
Jensen, G. L., Roy, M., Buchanan, A. E., & Berg, M. (2004) · Obesity Research · doi:10.1038/oby.2004.225 · Cited by 94 · see citing works
Diabetes, Inflammation, and Functional Decline in Older Adults
Figaro, M. K., Kritchevsky, S. B., Resnick, H. E., Shorr, R. I., Butler, J., Shintani, A., Penninx, B. W. J. H., Simonsick, E. M., Goodpaster, B. H., Newman, A. B., et al. (2006) · Diabetes Care · doi:10.2337/dc06-0245 · Cited by 91 · see citing works
Functional Impact of Relative Versus Absolute Sarcopenia in Healthy Older Women
Estrada, M. R., Kleppinger, A., Judge, J. O., Walsh, S. J., & Kuchel, G. A. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01436.x · Cited by 90 · see citing works
Kelly, K. R., Haus, J. M., Solomon, T. P. J., Patrick-Melin, A. J., Cook, M. D., Rocco, M. B., Barkoukis, H. D., & Kirwan, J. P. (2011) · Journal of Nutrition · doi:10.3945/jn.111.139964 · Cited by 83 · see citing works
Anton, S. D., Manini, T. M., Milsom, V. A., Dubyak, P. J., Cesari, M., Cheng, J., Daniels, M. J., Marsiske, M., Pahor, M., Leeuwenburgh, C., et al. (2011) · Clinical Interventions in Aging · doi:10.2147/cia.s17001 · Cited by 83 · see citing works
Self-citationFat mass loss predicts gain in physical function with intentional weight loss in older adults
Beavers, K. M., Miller, M. E., Rejeski, W. J., Nicklas, B. J., & Kritchevsky, S. B. (2013) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/gls092 · Cited by 82 · see citing works
The Framingham Disability Study: I. Social disability among the aging.
Branch, L. G., & Jette, A. M. (1981) · American Journal of Public Health · doi:10.2105/ajph.71.11.1202 · Cited by 80 · see citing works
Sarcopenic Obesity: An Emerging Cause of Frailty in Older Adults
Jarosz, P. A., & Bellar, A. (2008) · Geriatric Nursing · doi:10.1016/j.gerinurse.2008.02.010 · Cited by 75 · see citing works
Ryan, A. S., Ortmeyer, H. K., & Sorkin, J. D. (2011) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00618.2010 · Cited by 74 · see citing works
Effects of Exercise on Mobility in Obese and Nonobese Older Adults
Manini, T. M., Newman, A. B., Fielding, R. A., Blair, S. N., Perri, M. G., Anton, S. D., Goodpaster, B., Katula, J. A., Rejeski, W. J., Kritchevsky, S. B., et al. (2009) · Obesity · doi:10.1038/oby.2009.317 · Cited by 66 · see citing works
Self-citationObesity and Physical Inactivity: The Relevance of Reconsidering the Notion of Sedentariness
Chaput, J., & Tremblay, A. (2009) · Obesity Facts · doi:10.1159/000227287 · Cited by 64 · see citing works
Rodríguez‐Saldaña, J., Morley, J. E., Reynoso, M. T. M., Medina, C. A., Salazar, P., de la Cruz, E., & Torres, A. L. N. (2002) · Journal of the American Geriatrics Society · doi:10.1046/j.1532-5415.2002.50016.x · Cited by 62 · see citing works
Tsang, T. W., Orr, R., Lam, P., Comino, E. J., & Singh, M. F. (2007) · PubMed Central · Cited by 61 · see citing works
Andrade, F. C. D. (2009) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbp119 · Cited by 61 · see citing works
Tajiri, Y., Kato, T., Nakayama, H., & Yamada, K. (2009) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2009.0043 · Cited by 58 · see citing works
Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment.
Lamson, D. W., & Plaza, S. M. (2002) · PubMed · Cited by 57 · see citing works
Prévost, G., Fajardy, I., Besmond, C., Balkau, B., Tichet, J., Fontaine, P., Danzé, P. M., & Marre, M. (2005) · Diabetes & Metabolism · doi:10.1016/s1262-3636(07)70164-7 · Cited by 55 · see citing works
Obesity in the Elderly Diabetic Patient
Kyrou, I., & Tsigos, C. (2009) · Diabetes Care · doi:10.2337/dc09-s348 · Cited by 53 · see citing works
The effects of lifestyle interventions in dynapenic-obese postmenopausal women
Sénéchal, M., Bouchard, D. R., Dionne, I. J., & Brochu, M. (2012) · Menopause · doi:10.1097/gme.0b013e318248f50f · Cited by 48 · see citing works
Obesity, Disability, and Mortality
Ferrucci, L. (2007) · Archives of Internal Medicine · doi:10.1001/archinte.167.8.750 · Cited by 47 · see citing works
Editorial: Diabetes Mellitus: A Major Disease Of Older Persons
Morley, J. E. (2000) · The Journals of Gerontology Series A · doi:10.1093/gerona/55.5.m255 · Cited by 42 · see citing works
Straight, C. R., Dorfman, L. R., Cottell, K. E., Krol, J. M., Lofgren, I. E., & Delmonico, M. J. (2012) · Journal of Physical Activity and Health · doi:10.1123/jpah.9.6.875 · Cited by 40 · see citing works
Chiu, C., Wray, L. A., & Ofstedal, M. B. (2010) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2010.12.003 · Cited by 37 · see citing works
Lebrun, C. E. I., van der Schouw, Y. T., de Jong, F. H., Pols, H. A. P., Grobbee, D. E., & Lamberts, S. W. J. (2006) · Maturitas · doi:10.1016/j.maturitas.2006.01.008 · Cited by 36 · see citing works
Effect of Diabetes Mellitus on Muscle Size and Strength in Patients Receiving Dialysis Therapy
Sakkas, G. K., Kent‐Braun, J. A., Doyle, J., Shubert, T. E., Gordon, P., & Johansen, K. L. (2006) · American Journal of Kidney Diseases · doi:10.1053/j.ajkd.2006.01.013 · Cited by 33 · see citing works
Apostolopoulou, M. I., Savopoulos, C. G., Michalakis, K. G., Coppack, S. W., Dardavesis, T. I., & Hatzitolios, A. I. (2012) · Maturitas · doi:10.1016/j.maturitas.2011.11.015 · Cited by 33 · see citing works
Ostir, G. V., Volpato, S., Kasper, J. D., Ferrucci, L., & Guralnik, J. M. (2001) · PubMed · Cited by 28 · see citing works
Muszalik, M., Dijkstra, A., Kędziora–Kornatowska, K., Zielińska-Więczkowska, H., & Kornatowski, T. (2010) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2010.11.011 · Cited by 25 · see citing works
Atherosclerotic burden during the menopausal transition is a wakeup call
Wild, R. A. (2011) · Menopause The Journal of The North American Menopause Society · doi:10.1097/gme.0b013e31823434dc · Cited by 19 · see citing works
Nocera, J. R., Buford, T. W., Manini, T. M., Naugle, K. M., Leeuwenburgh, C., Pahor, M., Perri, M. G., & Anton, S. D. (2011) · Journal of Aging Research · doi:10.4061/2011/392510 · Cited by 15 · see citing works
Self-citationInsulin Resistance, Glycemic Control and Adiposity: Key Determinants of Healthy Lifespan
DiStefano, P. S., Curtis, R., & Geddes, B. J. (2007) · Current Alzheimer Research · doi:10.2174/156720507780362038 · Cited by 14 · see citing works
The shape of things to come: obesity, aging, and disability.
Alley, D. E., Chang, V. W., & Doshi, J. A. (2008) · PubMed · Cited by 12 · see citing works
Adherence to Behavioral and Pharmacological Interventions in Clinical Research on Older Adults
Shumaker, S. A., & Rejeski, W. J. (2000) · Controlled Clinical Trials · doi:10.1016/s0197-2456(00)00071-4 · Cited by 12 · see citing works
The role of obesity and cardiovascular fitness in the impaired glucose tolerance of aging
Colman, E. G., Katzel, L. I., Sorkin, J. D., Coon, P. J., Engelhardt, S. M., Rogus, E. M., & Goldberg, A. P. (1995) · Experimental Gerontology · doi:10.1016/0531-5565(95)00015-1 · Cited by 10 · see citing works
Muszalik, M., Dijkstra, A., Kędziora–Kornatowska, K., Zielińska-Więczkowska, H., Kornatowski, T., & Kotkiewicz, A. (2012) · Archives of Gerontology and Geriatrics · doi:10.1016/j.archger.2012.01.005 · Cited by 8 · see citing works
Flagged first, then by citations
1 of the 114 references couldn’t be matched to a known paper.
Research works printed but not linked: 3
- Davidson LE Hudson R Kilpatrick K Kuk JL McMillan K Janiszewski PM Lee S Lam M Ross R 2009 Effects of exercise modality on insulin resistance and functional limitation in older adults Arch Intern Med 169 2 122 131 19171808
- Taijiri Y Kato T Nakayama H Tamada K 2010 Reduction of skeletal muscle, especially in lower limbs, in Japanese type 2 diabetic patients with insulin resistance and cardiovascular risk factors Metab Syndr Relat Disord 8 2 137 142 19900156
- Tsang T Orr R Lam P Comino EJ Singh MF 2007 Health benefits of Tai Chi for older patients with diabetes: The “Move It for Diabetes Study Clin Interv Aging 2 3 429 439 18044193 PMC2685274
Cited by
Sorted by citations
Physical activity/exercise and diabetes: A position statement of the American Diabetes Association
Colberg, S. R., Sigal, R. J., Yardley, J. E., Riddell, M. C., Dunstan, D. W., Dempsey, P. C., Horton, E. S., Castorino, K., & Tate, D. F. (2016) · Diabetes Care · doi:10.2337/dc16-1728 · Cited by 2,991 · see citing works
Flipping the Metabolic Switch: Understanding and Applying the Health Benefits of Fasting
Anton, S. D., Moehl, K., Donahoo, W. T., Marosi, K., Lee, S. A., Mainous, A. G., Leeuwenburgh, C., & Mattson, M. P. (2017) · Obesity · doi:10.1002/oby.22065 · Cited by 782 · see citing works
Self-citationSuccessful aging: Advancing the science of physical independence in older adults
Anton, S. D., Woods, A. J., Ashizawa, T., Barb, D., Buford, T. W., Carter, C. S., Clark, D. J., Cohen, R. A., Corbett, D. B., Cruz-Almeida, Y., et al. (2015) · Ageing Research Reviews · doi:10.1016/j.arr.2015.09.005 · Cited by 292 · see citing works
Self-citationThe Effects of Time Restricted Feeding on Overweight, Older Adults: A Pilot Study
Anton, S. D., Lee, S. A., Donahoo, W. T., McLaren, C., Manini, T. M., Leeuwenburgh, C., & Pahor, M. (2019) · Nutrients · doi:10.3390/nu11071500 · Cited by 236 · see citing works
Self-citationTime-restricted eating: Watching the clock to treat obesity
Ezpeleta, M., Cienfuegos, S., Lin, S., Pavlou, V., Gabel, K., Tussing-Humphreys, L. M., & Varady, K. A. (2024) · Cell Metabolism · doi:10.1016/j.cmet.2023.12.004 · Cited by 161 · see citing works
Nicklas, B. J., Chmelo, E., Delbono, O., Carr, J. J., Lyles, M. F., & Marsh, A. P. (2015) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.105270 · Cited by 144 · see citing works
Rivas, D. A., McDonald, D. J., Rice, N. P., Haran, P. H., Dolnikowski, G. G., & Fielding, R. A. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00198.2015 · Cited by 132 · see citing works
Regulation of myokine expression: Role of exercise and cellular stress
Ost, M., Coleman, V., Kasch, J., & Klaus, S. (2016) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.02.018 · Cited by 131 · see citing works
Exploring the Impact of Obesity on Skeletal Muscle Function in Older Age
Morgan, P., Smeuninx, B., & Breen, L. (2020) · Frontiers in Nutrition · doi:10.3389/fnut.2020.569904 · Cited by 90 · see citing works
Yanai, H. (2015) · Journal of Clinical Medicine Research · doi:10.14740/jocmr2361w · Cited by 93 · see citing works
Implications of circulating Meteorin-like (Metrnl) level in human subjects with type 2 diabetes
Chung, H. S., Hwang, S. Y., Choi, J. H., Lee, H. J., Kim, N. H., Yoo, H. J., Seo, J. A., Kim, S. G., Kim, N. H., Baik, S. H., et al. (2017) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2017.11.031 · Cited by 96 · see citing works
Sphingolipid Metabolism and Signaling in Skeletal Muscle: From Physiology to Physiopathology
Tan, S., Guitton, J., Bourron, O., Stunff, H. L., & Hajduch, É. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.00491 · Cited by 85 · see citing works
Novel Smartphone Game Improves Physical Activity Behavior in Type 2 Diabetes
Höchsmann, C., Müller, O., Ambühl, M., Klenk, C., Königstein, K., Infanger, D., Walz, S. P., & Schmidt-Trucksäss, A. (2019) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2019.02.017 · Cited by 67 · see citing works
Tyrovolas, S., Koyanagi, A., Garín, N., Olaya, B., Ayuso‐Mateos, J. L., Miret, M., Chatterji, S., Tobiasz‐Adamczyk, B., Koskinen, S. V. P., Leonardi, M., et al. (2015) · Experimental Gerontology · doi:10.1016/j.exger.2015.02.010 · Cited by 70 · see citing works
Zhang, J., Tam, W., Hounsri, K., Kusuyama, J., & Wu, X. V. (2023) · Archives of Physical Medicine and Rehabilitation · doi:10.1016/j.apmr.2023.10.005 · Cited by 71 · see citing works
Long, G. H., Cooper, A., Wareham, N. J., Griffin, S. J., & Simmons, R. K. (2014) · Diabetes Care · doi:10.2337/dc13-1731 · Cited by 50 · see citing works
Deschenes, M. R., Sherman, E. G., Roby, M. A., Glass, E. K., & Harris, M. B. (2014) · Journal of Neuroscience Research · doi:10.1002/jnr.23495 · Cited by 46 · see citing works
François, M. E., Durrer, C. G., Pistawka, K. J., Halperin, F. A., Chang, C. R., & Little, J. P. (2017) · Frontiers in Physiology · doi:10.3389/fphys.2017.00528 · Cited by 45 · see citing works
Healthy behaviours and 10-year incidence of diabetes: A population cohort study
Long, G. H., Johansson, I., Rolandsson, O., Wennberg, P., Fhärm, E., Weinehall, L., Griffin, S. J., Simmons, R. K., & Norberg, M. (2014) · Preventive Medicine · doi:10.1016/j.ypmed.2014.12.013 · Cited by 40 · see citing works
Luoma, K., Leavitt, I. M., Marrs, J. C., Nederveld, A., Regensteiner, J. G., Dunn, A. L., Glasgow, R. E., & Huebschmann, A. G. (2017) · Translational Behavioral Medicine · doi:10.1007/s13142-017-0502-4 · Cited by 41 · see citing works
Anton, S. D., Ezzati, A., Witt, D., McLaren, C., & Vial, P. (2021) · Experimental Gerontology · doi:10.1016/j.exger.2021.111617 · Cited by 41 · see citing works
Self-citationMuscle Weakness Is Associated With Diabetes in Older Mexicans: The Mexican Health and Aging Study
Peterson, M. D., McGrath, R. P., Zhang, P., Markides, K. S., Snih, S. A., & Wong, R. (2016) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2016.06.007 · Cited by 36 · see citing works
Identifying Sarcopenia in Metabolic Syndrome: Data from the Berlin Aging Study II
Buchmann, N., Nikolov, J., Spira, D., Demuth, I., Steinhagen‐Thiessen, E., Eckardt, R., & Norman, K. (2015) · The Journals of Gerontology Series A · doi:10.1093/gerona/glv089 · Cited by 34 · see citing works
Klijs, B., Nusselder, W. J., Looman, C. W. N., & Mackenbach, J. P. (2014) · American Journal of Public Health · doi:10.2105/ajph.2014.301924 · Cited by 33 · see citing works
Physical Activity, Functional Ability, and Obesity in Older Adults: A Gender Difference
Gretebeck, K. A., Sabatini, L. M., Black, D. R., & Gretebeck, R. J. (2017) · Journal of Gerontological Nursing · doi:10.3928/00989134-20170406-03 · Cited by 32 · see citing works
Armstrong, M. J., & Sigal, R. J. (2015) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2015.09.081 · Cited by 29 · see citing works
Scott, D. S., Shore‐Lorenti, C., McMillan, L. B., Mesinovic, J., Clark, R. A., Hayes, A., Sanders, K. M., Duque, G., & Ebeling, P. R. (2018) · PubMed Central · Cited by 28 · see citing works
Wong, A. K. C., Wong, F. K. Y., & Chang, K. (2015) · Journal of Advanced Nursing · doi:10.1111/jan.12700 · Cited by 27 · see citing works
The Characteristics of Diabetic Residents in European Nursing Homes: Results from the SHELTER Study
Szczerbińska, K. E., Topinková, E., Brzyski, P., van der Roest, H. G., Richter, T., Finne‐Soveri, H., Denkinger, M. D., Gindin, J., Onder, G., & Bernabei, R. (2014) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2014.11.009 · Cited by 24 · see citing works
Condiciones de salud, síndromes geriátricos y estado nutricional de los adultos mayores en México
Salinas‐Rodríguez, A., la Cruz-Góngora, V. V. D., & Manrique-Espinoza, B. S. (2020) · Salud Pública de México · doi:10.21149/11840 · Cited by 22 · see citing works
Potential Mechanisms for How Long-Term Physical Activity May Reduce Insulin Resistance
Lee-Ødegård, S., Olsén, T., Norheim, F., Drevon, C. A., & Birkeland, K. I. (2022) · Metabolites · doi:10.3390/metabo12030208 · Cited by 20 · see citing works
Trojian, T. H., Colberg, S., Harris, G., Oh, R., Dixit, S., Gibson, M., Corcoran, M., Ramey, L., & Berg, P. V. (2021) · Clinical Journal of Sport Medicine · doi:10.1097/jsm.0000000000000906 · Cited by 20 · see citing works
Memelink, R. G., Hummel, M., Hijlkema, A., Streppel, M. T., Bautmans, I., Weijs, P. J. M., Berk, K. A., & Tieland, M. (2023) · Diabetic Medicine · doi:10.1111/dme.15096 · Cited by 18 · see citing works
François, M. E., Gillen, J. B., & Little, J. P. (2017) · Frontiers in Nutrition · doi:10.3389/fnut.2017.00049 · Cited by 19 · see citing works
Explanators of Sarcopenia in Individuals With Diabesity: A Cross-Sectional Analysis
Bittel, A. J., Bittel, D. C., Tuttle, L. J., Strube, M., Mueller, M. J., Cade, W. T., & Sinacore, D. R. (2016) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000076 · Cited by 17 · see citing works
A Phenomenological Study of Obesity and Physical Activity in Southern African American Older Women
Bowen, P. G., Eaves, Y. D., Vance, D. E., & Moneyham, L. D. (2014) · Journal of Aging and Physical Activity · doi:10.1123/japa.2013-0039 · Cited by 16 · see citing works
Theory of Planned Behavior: Social Support and Diabetes Self-Management
Lee, L. T., Bowen, P. G., Mosley, M. K., & Turner, C. C. (2017) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2016.07.013 · Cited by 16 · see citing works
Glucose regulation and physical performance among older people: the Helsinki Birth Cohort Study
Åström, M. J., von Bonsdorff, M. B., Perälä, M.-M., Salonen, M. K., Rantanen, T., Kajantie, E., Simonen, M., Pohjolainen, P., Osmond, C., & Eriksson, J. G. (2018) · Acta Diabetologica · doi:10.1007/s00592-018-1192-1 · Cited by 16 · see citing works
Armstrong, M. J., Colberg, S. R., & Sigal, R. J. (2015) · Diabetes Spectrum · doi:10.2337/diaspect.28.1.14 · Cited by 17 · see citing works
Saitoh, M., Ogawa, M., Kondo, H., Suga, K., Takahashi, T., Itoh, H., & Tabata, Y. (2019) · Renal Replacement Therapy · doi:10.1186/s41100-019-0240-9 · Cited by 18 · see citing works
Vieira, E. R., Mendy, A., Prado, C. M. M., Gasana, J., & Albatineh, A. N. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.08.005 · Cited by 15 · see citing works
The emerging global phenomenon of sarcopenic obesity: Role of functional foods; a conference report
Shao, A. E., Campbell, W. W., Chen, C. O., Mittendorfer, B., Rivas, D. A., & Griffiths, J. C. (2017) · Journal of Functional Foods · doi:10.1016/j.jff.2017.03.048 · Cited by 15 · see citing works
Lee, Y. J., Kim, G. H., Park, S. I., & Lim, J. H. (2019) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.14799 · Cited by 15 · see citing works
Ard, J. D., Cook, M., Rushing, J., Frain, A., Beavers, K. M., Miller, G., Miller, M. E., & Nicklas, B. (2016) · Obesity · doi:10.1002/oby.21569 · Cited by 14 · see citing works
A Chinese Chan-based Mind-Body Intervention Improves Memory of Older Adults
Chan, A. S.-Y., Cheung, W. K., Yeung, M. K.-C., Woo, J., Kwok, T. C. Y., Shum, D., Yu, R., & Cheung, M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00190 · Cited by 15 · see citing works
Estela-Ayamamani, D., Espinoza-Figueroa, J., Columbus-Morales, M., Runzer-Colmenares, F. M., Parodi, J. F., & Mayta‐Tristán, P. (2014) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2014.11.001 · Cited by 12 · see citing works
Greco, F., Tarsitano, M. G., Cosco, L. F., Quinzi, F., Folino, K., Spadafora, M., Afzal, M., Segura‐Garcìa, C., Maurotti, S., Pujia, R., et al. (2024) · Nutrients · doi:10.3390/nu16060902 · Cited by 11 · see citing works
Wang, L., Zhu, H., Chen, H., Ziyi, H., Feng, M., Menglin, T., & Hu, X. (2025) · BMC Public Health · doi:10.1186/s12889-024-21234-w · Cited by 10 · see citing works
Hu, Y., Malyutina, S. K., Pikhart, H., Peasey, A., Holmes, M. V., Hubacek, J. A., Вахтанговна, Д. Д., Nikitin, Y., & Bobák, M. (2016) · The journal of nutrition health & aging · doi:10.1007/s12603-016-0769-z · Cited by 10 · see citing works
Sones, B. E., & Devlin, B. L. (2024) · Nutrition Reviews · doi:10.1093/nutrit/nuae044 · Cited by 9 · see citing works
Jiménez‐Martínez, P., Ramírez‐Campillo, R., Alix‐Fages, C., Gené‐Morales, J., García‐Ramos, A., & Colado, J. C. (2023) · Healthcare · doi:10.3390/healthcare11040594 · Cited by 9 · see citing works
How Overweight and Obesity Relate to the Development of Functional Limitations among Filipino Women
Adair, L. S., Duazo, P. L., & Borja, J. B. (2018) · Geriatrics · doi:10.3390/geriatrics3040063 · Cited by 9 · see citing works
Wojszel, Z. B., & Magnuszewski, Ł. (2020) · Diabetes Metabolic Syndrome and Obesity · doi:10.2147/dmso.s279388 · Cited by 9 · see citing works
Depression and physical functioning among older Americans with diabesity
Bowen, P. G., Lee, L. T., Martin, M. Y., & Clay, O. J. (2017) · Journal of the American Association of Nurse Practitioners · doi:10.1002/2327-6924.12393 · Cited by 9 · see citing works
Effects of lifestyle interventions on rural patients with type 2 diabetes mellitus
Wang, B., Mu, X.-L., Zhao, J., Jiang, H.-P., Li, S.-S., Yan, G., Hua, Y.-Y., Ren, X.-Y., Xing, L.-X., Liang, Y., et al. (2020) · World Journal of Diabetes · doi:10.4239/wjd.v11.i6.261 · Cited by 9 · see citing works
Sarcopenia and body composition in diabetic Charcot osteoarthropathy
Jansen, R. B., Christensen, T. M., Bülow, J., Rørdam, L., Holstein, P., & Svendsen, O. L. (2015) · Journal of Diabetes and its Complications · doi:10.1016/j.jdiacomp.2015.05.020 · Cited by 8 · see citing works
Diretriz BRASPEN de Terapia Nutricional no Diabetes Mellitus
Campos, L. F., Borges, V. C., Barreto, P. A., González, M. C., Ceniccola, G. D., de Abreu, H. B., Alves, J. T. M., Segadilha, N. L. A. L., Kumbier, M. C. C., & Castro, M. G. (2020) · Braspen Journal · doi:10.37111/braspenj.diretrizdm2020 · Cited by 7 · see citing works
Lixisenatide improves glycemic outcomes of Japanese patients with type 2 diabetes: a meta-analysis
Seino, H., Onishi, Y., Naito, Y., & Komatsu, M. (2016) · Diabetology & Metabolic Syndrome · doi:10.1186/s13098-016-0151-7 · Cited by 8 · see citing works
Physical inactivity, television time and chronic diseases in Brazilian adults and older adults
Christofoletti, M., Duca, G. F. D., da Silva, K. S., Meneghini, V., & Malta, D. C. (2019) · Health Promotion International · doi:10.1093/heapro/daz031 · Cited by 7 · see citing works
Norris, T., Blodgett, J. M., Rogers, N. T., Hamer, M., & Pereira, S. M. P. (2022) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2022.03.008 · Cited by 7 · see citing works
Factors related to depressive symptoms in older adult patients with type 2 Diabetes Mellitus
Filho, B. F. D. L., Dias, V. D. N., Carlos, A. G., Fontes, F. P., de Sousa, A. G. P., & Gazzola, J. M. (2018) · Experimental Gerontology · doi:10.1016/j.exger.2018.11.006 · Cited by 7 · see citing works
Novel insights regarding mechanisms for treatment of sarcopenia
Kraemer, R. R., & Castracane, V. D. (2014) · Metabolism · doi:10.1016/j.metabol.2014.11.002 · Cited by 7 · see citing works
Kioh, S. H., Mat, S., Kamaruzzaman, S. B., Ibrahim, F., Mokhtar, M. S., Hairi, N. N., Cumming, R. G., Myint, P. K., & Tan, M. P. (2019) · Journal of Aging and Physical Activity · doi:10.1123/japa.2019-0011 · Cited by 6 · see citing works
Gobbi, A., de Carvalho, G., Sapalo, A. T., & Guirro, R. R. D. J. (2020) · Lasers in Medical Science · doi:10.1007/s10103-020-03135-7 · Cited by 6 · see citing works
A Phenomenological Study of Obesity and Physical Activity in Southern African American Older Women
Bowen, P. G., Eaves, Y. D., Vance, D. E., & Moneyham, L. D. (2015) · Journal of Aging and Physical Activity · doi:10.1123/japa.23.2.221 · Cited by 6 · see citing works
Lifestyle Changes in the Prevention of Mobility Disability
(2014) · Healthy Aging & Clinical Care in the Elderly · doi:10.4137/hacce.s12502 · Cited by 6 · see citing works
Assessment procedures including comprehensive geriatric assessment
Valencia, W. M., Danet‐Lamasou, M., Florez, H. J., & Bourdel‐Marchasson, I. (2017) · Wiley eBooks · doi:10.1002/9781118954621.ch5 · Cited by 5 · see citing works
Bradway, C. K., & Felix, H. C. (2018) · Research in Gerontological Nursing · doi:10.3928/19404921-20171220-01 · Cited by 5 · see citing works
The DASH diet in diabetes related complications or comorbidities: an unexpected friend
Liu, K., Liu, S., Wang, D., & Qiao, H. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1689467 · Cited by 4 · see citing works
Minasian, V., & Nazari, M. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.122114 · Cited by 6 · see citing works
Dedov, V. N., & Dedova, I. V. (2015) · JMIR Rehabilitation and Assistive Technologies · doi:10.2196/rehab.4812 · Cited by 4 · see citing works
Sinclair, A. J., Sinclair, H., Bellary, S., & Rodríguez‐Mañas, L. (2016) · Cardiovascular Endocrinology · doi:10.1097/xce.0000000000000075 · Cited by 4 · see citing works
A scientometric analysis of sarcopenic obesity: Future trends and new perspectives
Tutan, D., & Uzeli, Ü. Ş. (2023) · Medicine · doi:10.1097/md.0000000000034244 · Cited by 4 · see citing works
Hernández‐Díaz, C., van Schoor, N. M., & Khalil, A. A. F. (2017) · Springer eBooks · doi:10.1007/978-3-319-59963-2_9 · Cited by 4 · see citing works
Ashraf, H., Maghbouli, N., Abolhasani, M., Zandi, N., Nematizadeh, M., Omidi, N., Davoodi, G., Boroumand, M. A., & Haidar, J. (2024) · Journal of Health Population and Nutrition · doi:10.1186/s41043-024-00668-3 · Cited by 4 · see citing works
Diabetes and functional limitation
Rodríguez‐Mañas, L., & Sinclair, A. J. (2017) · doi:10.1002/9781118954621.ch16 · Cited by 3 · see citing works
Type 1 Diabetes, Exercise and Nutrition
Kenger, E. B., & Ergün, C. (2019) · Turkiye Klinikleri Journal of Sports Sciences · doi:10.5336/sportsci.2019-70286 · Cited by 2 · see citing works
Youssef, M. K. (2023) · Physiotherapy Quarterly · doi:10.5114/pq.2023.117072 · Cited by 2 · see citing works
MacNeil, A., Cottagiri, S. A., Villeneuve, P. J., Jiang, Y., de Groh, M., & Fuller‐Thomson, E. (2024) · Canadian Journal of Diabetes · doi:10.1016/j.jcjd.2024.02.005 · Cited by 2 · see citing works
The association between difficult-to-treat rheumatoid arthritis and probable sarcopenia
Ohashi, Y., Suzuki, M., Sobue, Y., Terabe, K., Asai, S., Takahashi, N., & Imagama, S. (2024) · Modern Rheumatology · doi:10.1093/mr/roae116 · Cited by 2 · see citing works
Physioprophylaxis of type 1 diabetes in children using physical exercise
Zaworski, K., Ławnik, A., Kubińska, Z., & Shpakou, A. (2019) · Health Problems of Civilization · doi:10.5114/hpc.2019.89834 · Cited by 2 · see citing works
Balboa-Vásquez, J., Domínguez-Reyes, A., Martín, Y. E.-S., Pavicic, F., Ehrenfeld, P., & Martínez-Huenchullán, S. (2021) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2020.11.004 · Cited by 2 · see citing works
Ma, M., Tang, Z.-L., Chen, L.-P., Qin, X.-N., Xiao, K.-F., Zhu, W., Zhang, Y., & Gong, Z. (2025) · Cells · doi:10.3390/cells14120874 · Cited by 1 · see citing works
Complications and Comorbidities in Individuals >80 Years with Diabetes: A Scoping Review
Ward-Bradley, C., Erwin, A., Pető, T., Cushley, L. N., & Curran, K. (2025) · Diabetology · doi:10.3390/diabetology6120152 · Cited by 1 · see citing works
Functional disability for mobility in adults: a population-based study
Yonamine, C. Y., Matsuo, T., de Souza, R. K. T., Loch, M. R., & Cabrera, M. A. S. (2016) · Fisioterapia em Movimento · doi:10.1590/1980-5918.029.003.ao02 · Cited by 1 · see citing works
Ahmad, S. (2013) · Human Biology
Keski-ikäisten sairaanhoitajien työkuormituksen yhteys vanhuuden toimintakykyyn
Kempas, M. (2015) · Jyväskylä University Digital Archive (University of Jyväskylä)
Dedov, V. N., & Dedova, I. V. (2016) · JMIR Research Protocols · doi:10.2196/resprot.4985
Shahadan, S. Z., Daud, A., Md. Isa, M. L., Ibrahim, M., & Deraman, S. (2020) · IIUM Medical Journal Malaysia · doi:10.31436/imjm.v18i2.102
Lifestyle Management for People with Diabetes – What You Need to Know From the ADA Standards of Care
Pfotenhauer, K. M., Dugan, J. A., Bradley, S., Shubrook, J. H., & Rhinehart, A. S. (2017) · Touro Scholar (Touro College) · doi:10.1016/ofp.v9i5.516
How can older adults combat diabetes to achieve a longer and healthier life
Shang, Y. (2021) · Figshare
Physical Exercise and Falling among Older Patients with Diabetes: A Narrative Review
Abdelbasset, W. K. (2021) · International Journal of Biomedicine · doi:10.21103/article11(4)_ra3
Pathophysiology of Diabetes‐Induced Complications
Dahiya, R., Buttar, H. S., & Gupta, S. (2022) · Wiley eBooks · doi:10.1002/9781119746843.ch30
Della, L. J., Reitenga, A., & King, K. M. (2023) · ACSMʼs Health & Fitness Journal · doi:10.1249/fit.0000000000000844
Ashraf, H., Maghbouli, N., Abolhasani, M., Zandi, N., Nematizadeh, M., Omidi, N., Davoodi, G., Boroumand, M. A., & Haidar, J. (2023) · Research Square · doi:10.21203/rs.3.rs-3303747/v1
Exercise benefits and barriers in an extension‐delivered diabetes prevention program
Castillo‐Hernández, I. M., Wilson, H. K., Williams, E. R., Berg, A. C., & Evans, E. M. (2025) · Family and Consumer Sciences Research Journal · doi:10.1111/fcsr.70000
Exercise and Endocrine Diseases
Selk-Ghaffari, M., Shahi, M. H. P., & Kordi, R. (2025) · Springer eBooks · doi:10.1007/978-981-95-2286-6_12
Exercise and Type 2 Diabetes Mellitus
Ahmed, A., & Ismail, S. M. (2026) · IntechOpen eBooks · doi:10.5772/intechopen.1011038 · Cited by 1 · see citing works
- Authors
- Anton, S. D., Karabetian, C., Naugle, K., & Buford, T. W.
- Affiliations
- University of Florida (US)
- Corresponding author
- Anton, Stephen D.
- Buford, Thomas W.
- Venue
- Experimental Gerontology
- Publisher
- Elsevier BV
- Published
- 2013-09
- Volume
- 48
- Issue
- 9
- Pages
- 888-897
- ISSN
- 0531-5565 (ISSN-L)
- PMC
- PMC3817488
- OpenAlex
- W2062831962
- Cited by
- 100
- References
- 114
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 6 · 2023: 8 · 2022: 3 · 2021: 5 · 2020: 8 · 2019: 8 · 2018: 6 · 2017: 14 · 2016: 11 · 2015: 14 · 2014: 9 · 2013: 1
- FWCI
- 1.29
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Experimental Gerontology (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- University of Florida Claude D. Pepper Older Americans Independence Center (P30AG028740)
- Topics
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Aging, Health, and Disability
- Keywords
- obesity, diabetes mellitus, functional decline, sarcopenia, physical disability, older adults, lifestyle intervention, metabolic dysfunction, muscle mass and strength
- MeSH terms
- Aged, Aging, Diet, Humans, Life Style, Obesity, Risk Factors, Exercise, Disease Progression, Diabetes Complications, Sarcopenia
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
