The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Treatment of symptomatic rectovaginal endometriosis with an estrogen–progestogen combination versus low-dose norethindrone acetate
Open accessAbstract
Objective To evaluate the efficacy, safety, and tolerability of an estrogen-progestogen combination versus low-dose norethindrone acetate in the treatment of persistent pain after surgery for symptomatic rectovaginal endometriosis.Design Randomized controlled trial.Setting Academic center.Patient(s) Ninety women with recurrent moderate or severe pelvic pain after unsuccessful conservative surgery for symptomatic rectovaginal endometriosis.Intervention(s) Twelve-month, continuous treatment with oral ethinyl E2, 0.01 mg, plus cyproterone acetate, 3 mg/day, or norethindrone acetate, 2.5 mg/day.Main outcome measure(s) Degree of satisfaction with therapy.Result(s) Seven women in the ethinyl E2 plus cyproterone acetate arm and five in the norethindrone acetate arm withdrew because of side effects (n=5), treatment inefficacy (n=6), or loss to follow-up (n=1). At 12 months, dysmenorrhea, deep dyspareunia, nonmenstrual pelvic pain, and dyschezia scores were substantially reduced without major between-group differences. Both regimens induced minor unfavorable variations in the serum lipid profile. According to an intention-to-treat analysis, 28 (62%) out of 45 patients in the ethinyl E2 plus cyproterone acetate group and 33 (73%) out of 45 in the norethindrone acetate group were satisfied with the treatment received.Conclusion(s) Low-dose norethindrone acetate could be considered an effective, tolerable, and inexpensive first-choice medical alternative to repeat surgery for treating symptomatic rectovaginal endometriotic lesions in patients who do not seek conception.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Low-dose NETA 2.5 mg/day orally is considered an effective, tolerable and inexpensive first choice for symptomatic rectovaginal endometriosis, significantly decreasing VAS scores for dysmenorrhea and dyspareunia [209].”
From Hormonal treatments for endometriosis: The endocrine background (2022) · cites this paper as [209]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“whereas low-dose oral NETA is probably the best choice for rectovaginal lesions”
From “Waiting for Godot”: a commonsense approach to the medical treatment of endometriosis (2011) · cites this paper as Vercellini et al., 2005
Experimental — accuracy not yet measuredThe cited source says what the claim attributes to it.
In the citing paper
“Reported response rates for therapy with 2.5 mg norethindrone acetate per day in endometriosis-associated pain range between 74 and 92%.”
From Pain and functional outcomes after surgical versus hormonal treatment in rectovaginal endometriosis: a retrospective cohort study (2026) · cites this paper as [29]
The cited source says what the claim attributes to it.
In the citing paper
“Evidence for hormonal treatment specifically in RVE is less abundant and only one randomised-controlled trial was identified in the literature [29].”
From Pain and functional outcomes after surgical versus hormonal treatment in rectovaginal endometriosis: a retrospective cohort study (2026) · cites this paper as [29]
In the citing paper
“Based on our previous experience, the proportion of endometriosis patients satisfied with OC treatment is $65% (20,57).”
From A stepped-care approach to symptomatic endometriosis management: A participatory research initiative (2018) · cites this paper as [20]
In the citing paper
“Both treatments were equally effective in the management of pain symptoms and on the reduction of lesion size at ultrasound.”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [13]
In the citing paper
“Overall, 73% women in the NETA group were satisfied or very satisfied with treatment compared to 62% in the EP group.”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [13]
In the citing paper
“The lower dosage increases the tolerability, reducing weight gain and androgenic side effects, and limits the negative impact on serum cholesterol values [13].”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [13]
In the citing paper
“numerous studies by independent groups demonstrated the efficacy of a reduced daily dose of 2.5 mg [13-16].”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [13]
In the citing paper
“in Italy, the monthly cost of treatment with 2.5 mg/d is less than 2 US $ [13].”
From Oral and depot progestin therapy for endometriosis: towards a personalized medicine (2017) · cites this paper as [13]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Revised American Fertility Society Classification of Endometriosis: 1985
(1985) · Fertility and Sterility · doi:10.1016/s0015-0282(16)48430-x · Cited by 1,803
Endometriosis and pelvic pain: relation to disease stage and localization
Vercellini, P., Trespidi, L., De Giorgi, O., Cortesi, I., Parazzini, F., & Crosignani, P. G. (1996) · Fertility and Sterility · doi:10.1016/s0015-0282(16)58089-3 · Cited by 457
Self-citationUse of a levonorgestrel-releasing intrauterine device in the treatment of rectovaginal endometriosis
Fedele, L., Bianchi, S., Zanconato, G., Portuese, A., & Raffaelli, R. (2001) · Fertility and Sterility · doi:10.1016/s0015-0282(00)01759-3 · Cited by 290
Vercellini, P., Frontino, G., De Giorgi, O., Pietropaolo, G., Pasin, R., & Crosignani, P. G. (2003) · Fertility and Sterility · doi:10.1016/s0015-0282(03)00794-5 · Cited by 289
Self-citationDosage aspects of danazol therapy in endometriosis: Short-term and long-term effectiveness
Biberoglu, K. O., & Behrman, S. J. (1981) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(81)90478-6 · Cited by 267
Progestins for symptomatic endometriosis: a critical analysis of the evidence
Vercellini, P., Cortesi, I., & Crosignani, P. G. (1997) · Fertility and Sterility · doi:10.1016/s0015-0282(97)00193-3 · Cited by 229
Self-citationLong-term follow-up after conservative surgery for rectovaginal endometriosis
Fedele, L., Bianchi, S., Zanconato, G., Bettoni, G., & Gotsch, F. (2004) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2003.10.698 · Cited by 216
Deep Endometriosis: Definition, Pathogenesis, and Clinical Management
Vercellini, P., Frontino, G., Pietropaolo, G., Gattei, U., Daguati, R., & Crosignani, P. G. (2004) · The Journal of the American Association of Gynecologic Laparoscopists · doi:10.1016/s1074-3804(05)60190-9 · Cited by 180
Self-citationVercellini, P., De Giorgi, O., Mosconi, P., Stellato, G., Vicentini, S., & Crosignani, P. G. (2002) · Fertility and Sterility · doi:10.1016/s0015-0282(01)02951-x · Cited by 180
Self-citationProlonged GnRH agonist and add-back therapy for symptomatic endometriosis: long-term follow-up*1
Surrey, E. S. (2002) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(02)01945-2 · Cited by 167
Cited by
Sorted by citations
Endometriosis: pathogenesis and treatment
Vercellini, P., Viganò, P., Somigliana, E., & Fedele, L. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.255 · Cited by 1,940
Self-citationZondervan, K. T., Becker, C. M., Koga, K., Missmer, S. A., Taylor, R. N., & Viganò, P. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0008-5 · Cited by 1,257
Systematic review of endometriosis pain assessment: how to choose a scale?
Bourdel, N., Alves, J., Pickering, G. P., Ramilo, I. D. T. M., Roman, H., & Canis, M. J. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmu046 · Cited by 378
The effect of surgery for symptomatic endometriosis: the other side of the story
Vercellini, P., Crosignani, P. G., Abbiati, A., Somigliana, E., Viganò, P., & Fedele, L. (2009) · Human Reproduction Update · doi:10.1093/humupd/dmn062 · Cited by 339
Self-citationHormonal treatments for endometriosis: The endocrine background
Vannuccini, S., Clemenza, S., Rossi, M., & Petraglia, F. (2022) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-021-09666-w · Cited by 336
Reevaluating response and failure of medical treatment of endometriosis: a systematic review
Becker, C. M., Gattrell, W. T., Gude, K., & Singh, S. S. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.05.004 · Cited by 302
Piketty, M., Chopin, N., Dousset, B. E., Millischer, A., Roseau, G., Leconte, M., Borghese, B., & Chapron, C. (2008) · Human Reproduction · doi:10.1093/humrep/den405 · Cited by 284
Donnez, J., & Squifflet, J. (2010) · Human Reproduction · doi:10.1093/humrep/deq135 · Cited by 265
Progestagens and anti-progestagens for pain associated with endometriosis
Brown, J., Kives, S., & Akhtar, M. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd002122.pub2 · Cited by 250
Estrogen-progestins and progestins for the management of endometriosis
Vercellini, P., Buggio, L., Berlanda, N., Barbara, G., Somigliana, E., & Bosari, S. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.10.022 · Cited by 243
Self-citationBowel endometriosis: Diagnosis and management
Nezhat, C., Li, A., Falik, R., Copeland, D., Razavi, G., Shakib, A., Mihailide, C., Bamford, H., DiFrancesco, L., Tazuke, S., et al. (2018) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2017.09.023 · Cited by 205
Oral contraceptives for pain associated with endometriosis
Brown, J., Crawford, T. J., Datta, S., & Prentice, A. (2018) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd001019.pub3 · Cited by 199
Chapron, C., Bourret, A., Chopin, N., Dousset, B. E., Leconte, M., Amsellem‐Ouazana, D., de Ziegler, D., & Borghese, B. (2010) · Human Reproduction · doi:10.1093/humrep/deq017 · Cited by 197
Medical treatment of endometriosis-related pain
Vercellini, P., Buggio, L., Frattaruolo, M. P., Borghi, A., Dridi, D., & Somigliana, E. (2018) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2018.01.015 · Cited by 188
Self-citationLeone Roberti Maggiore, U., Ferrero, S., Candiani, M., Somigliana, E., Viganò, P., & Vercellini, P. (2017) · European Urology · doi:10.1016/j.eururo.2016.12.015 · Cited by 187
Self-citationEndometriosis: Current Therapies and New Pharmacological Developments
Vercellini, P., Somigliana, E., Viganò, P., Abbiati, A., Barbara, G., & Crosignani, P. G. (2009) · Drugs · doi:10.2165/00003495-200969060-00002 · Cited by 182
Self-citation“Waiting for Godot”: a commonsense approach to the medical treatment of endometriosis
Vercellini, P., Crosignani, P., Somigliana, E., Vigano, P., Frattaruolo, M. P., & Fedele, L. (2011) · Human Reproduction · doi:10.1093/humrep/deq302 · Cited by 180
“…may constitute an adequate first-line option for peritoneal and ovarian endometriosis (Vercellini et al., 2003b, 2008a, 2009c), whereas low-dose oral NETA is probably the best choice for rectovaginal lesions (Vercellini et al., 2005, 2009d; Remorgida et al., 2007a; Ferrero et al., 2009b, 2010b,c).”
BackgroundSelf-citationMedical Management of Endometriosis
RAFIQUE, S., & DECHERNEY, A. H. (2017) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000292 · Cited by 173
Reis, F. M., Coutinho, L. M., Vannuccini, S., Batteux, F., Chapron, C., & Petraglia, F. (2020) · Human Reproduction Update · doi:10.1093/humupd/dmaa009 · Cited by 166
Laparoscopic colorectal resection for deep infiltrating endometriosis: analysis of 436 cases
Ruffo, G., Scopelliti, F., Scioscia, M., Ceccaroni, M., Mainardi, P., & Minelli, L. (2010) · Surgical Endoscopy · doi:10.1007/s00464-009-0517-0 · Cited by 156
Reproductive performance in infertile women with rectovaginal endometriosis: Is surgery worthwhile?
Vercellini, P., Pietropaolo, G., Giorgi, O. D., Daguati, R., Pasin, R., & Crosignani, P. G. (2006) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2006.03.068 · Cited by 152
Self-citationNon-Contraceptive Benefits of Oral Hormonal Contraceptives
Schindler, A. E. (2012) · Intern J Endocrinol Metab · doi:10.5812/ijem.4158 · Cited by 152
Current and emerging treatment options for endometriosis
Ferrero, S., Evangelisti, G., & Barra, F. (2018) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2018.1494154 · Cited by 152
Medical treatment for rectovaginal endometriosis: what is the evidence?
Vercellini, P., Crosignani, P. G., Somigliana, E., Berlanda, N., Barbara, G., & Fedele, L. (2009) · Human Reproduction · doi:10.1093/humrep/dep231 · Cited by 144
Self-citationMore than just bad sex: sexual dysfunction and distress in patients with endometriosis
Fritzer, N., Haas, D., Oppelt, P., Renner, S. P., Hornung, D., Wölfler, M. M., Ulrich, U. A., Fischerlehner, G., Sillem, M., & Hudelist, G. (2013) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.04.001 · Cited by 146
Farquhar, C. M. (2007) · BMJ · doi:10.1136/bmj.39073.736829.be · Cited by 146
Chronic pelvic pain in women: etiology, pathogenesis and diagnostic approach
Vercellini, P., Somigliana, E., Viganò, P., Abbiati, A., Barbara, G., & Fedele, L. (2009) · Gynecological Endocrinology · doi:10.1080/09513590802549858 · Cited by 138
Self-citationEndometriosis: current and future medical therapies
Vercellini, P., Somigliana, E., Viganò, P., Abbiati, A., Daguati, R., & Crosignani, P. G. (2007) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2007.10.001 · Cited by 136
Self-citationFerrero, S., Camerini, G., Seracchioli, R., Ragni, N., Venturini, P., & Remorgida, V. (2009) · Human Reproduction · doi:10.1093/humrep/dep302 · Cited by 145
Current and Emerging Therapeutics for the Management of Endometriosis
Ferrero, S., Barra, F., & Maggiore, U. L. R. (2018) · Drugs · doi:10.1007/s40265-018-0928-0 · Cited by 135
Walch, K., Unfried, G., Huber, J., Kurz, C., van Trotsenburg, M., Pernicka, E., & Wenzl, R. (2009) · Contraception · doi:10.1016/j.contraception.2008.07.017 · Cited by 128
Vercellini, P., Somigliana, E., Consonni, D., Frattaruolo, M. P., De Giorgi, O., & Fedele, L. (2012) · Human Reproduction · doi:10.1093/humrep/des313 · Cited by 129
Self-citationVercellini, P., Bracco, B., Mosconi, P., Roberto, A., Alberico, D., Dhouha, D., & Somigliana, E. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.11.016 · Cited by 127
Self-citationTreatment of pain associated with deep endometriosis: alternatives and evidence
Ferrero, S., Alessandri, F., Racca, A., & Maggiore, U. L. R. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.08.031 · Cited by 124
Hormonal contraception in women with endometriosis: a systematic review
Grandi, G., Barra, F., Ferrero, S., Sileo, F. G., Bertucci, E., Napolitano, A., & Facchinetti, F. (2019) · The European Journal of Contraception & Reproductive Health Care · doi:10.1080/13625187.2018.1550576 · Cited by 122
Vercellini, P., Somigliana, E., Viganò, P., Matteis, S. D., Barbàra, G., & Fedele, L. (2010) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2010.04.018 · Cited by 121
Self-citationStrowitzki, T., Faustmann, T., Gerlinger, C., Schumacher, U., Ahlers, C., & Seitz, C. (2015) · International Journal of Women's Health · doi:10.2147/ijwh.s77202 · Cited by 120
“6,16,24 Weight gain is a common adverse effect of progestins including medroxyprogesterone acetate and norethindrone acetate 6,20,26,27 and is often perceived adversely by patients.”
Jensen, J. T., Schlaff, W., & Gordon, K. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.03.012 · Cited by 113
Comparison of contraceptive ring and patch for the treatment of symptomatic endometriosis
Vercellini, P., Barbàra, G., Somigliana, E., Bianchi, S., Abbiati, A., & Fedele, L. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2009.01.071 · Cited by 112
Self-citationNorethisterone acetate in the treatment of colorectal endometriosis: a pilot study
Ferrero, S., Camerini, G., Ragni, N., Venturini, P. L., Biscaldi, E., & Remorgida, V. (2010) · Human Reproduction · doi:10.1093/humrep/dep361 · Cited by 107
Barra, F., Scala, C., & Ferrero, S. (2018) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2018.1461840 · Cited by 100
An update on the pharmacological management of endometriosis
Streuli, I., de Ziegler, D., Santulli, P., Marcellin, L., Borghese, B., Batteux, F., & Chapron, C. (2013) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2013.767334 · Cited by 109
Efficacy of vaginal danazol treatment in women with recurrent deeply infiltrating endometriosis
Razzi, S., Luisi, S., Calonaci, F., Altomare, A., Bocchi, C., & Petraglia, F. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.12.077 · Cited by 100
Dienogest or Norethindrone acetate for the treatment of ovarian endometriomas: Can we avoid surgery?
Del Forno, S., Mabrouk, M., Arena, A., Mattioli, G., Giaquinto, I., Paradisi, R., & Seracchioli, R. (2019) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2019.04.010 · Cited by 88
Vercellini, P., Frattaruolo, M. P., Somigliana, E., Jones, G. L., Consonni, D., Alberico, D., & Fedele, L. (2013) · Human Reproduction · doi:10.1093/humrep/det041 · Cited by 97
Self-citationDeep dyspareunia and sex life after laparoscopic excision of endometriosis
Ferrero, S., Abbamonte, L. H., Giordano, M., Ragni, N., & Remorgida, V. (2006) · Human Reproduction · doi:10.1093/humrep/del465 · Cited by 98
Hormonal therapy for endometriosis: from molecular research to bedside
Tosti, C., Biscione, A., Morgante, G., Bifulco, G., Luisi, S., & Petraglia, F. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.05.032 · Cited by 96
Morotti, M., Sozzi, F., Remorgida, V., Venturini, P. L., & Ferrero, S. (2014) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2014.10.036 · Cited by 84
Medical Treatments for Endometriosis-Associated Pelvic Pain
Zito, G., Luppi, S., Giolo, E., Martinelli, M., Venturin, I., Lorenzo, G. D., & Ricci, G. (2014) · BioMed Research International · doi:10.1155/2014/191967 · Cited by 94
Letrozole and norethisterone acetate in colorectal endometriosis
Ferrero, S., Camerini, G., Ragni, N., Venturini, P. L., Biscaldi, E., Seracchioli, R., & Remorgida, V. (2010) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2010.02.023 · Cited by 80
Barbàra, G., Facchin, F., Buggio, L., Somigliana, E., Berlanda, N., Kustermann, A., & Vercellini, P. (2017) · Reproductive Sciences · doi:10.1177/1933719117707054 · Cited by 90
Self-citationLeone Roberti Maggiore, U., Remorgida, V., Scala, C., Tafi, E., Venturini, P. L., & Ferrero, S. (2014) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.12326 · Cited by 80
Safety of medical treatments for endometriosis
Berlanda, N., Somigliana, E., Viganò, P., & Vercellini, P. (2016) · Expert Opinion on Drug Safety · doi:10.1517/14740338.2016.1121991 · Cited by 78
Self-citationEffect of progestogens and combined oral contraceptives on nerve fibers in peritoneal endometriosis.
Tokushige, N., Markham, R., Russell, P., & Fraser, I. (2009) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.07.1774 · Cited by 69
Deep dyspareunia: causes, treatments, and results
Ferrero, S., Ragni, N., & Remorgida, V. (2008) · Current Opinion in Obstetrics & Gynecology · doi:10.1097/gco.0b013e328305b9ca · Cited by 78
Caruso, S., Iraci, M., Cianci, S., Fava, V., Casella, E., & Cianci, A. (2016) · Journal of Endocrinological Investigation · doi:10.1007/s40618-016-0460-6 · Cited by 77
A Lifelong Impact on Endometriosis: Pathophysiology and Pharmacological Treatment
Chen, L.-H., Lo, W.-C., Huang, H.-Y., & Wu, H. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087503 · Cited by 94
Ferrero, S., Venturini, P. L., Gillott, D. J., & Remorgida, V. (2011) · Reproductive Biology and Endocrinology · doi:10.1186/1477-7827-9-88 · Cited by 77
Priorities for Endometriosis Research: A Proposed Focus on Deep Dyspareunia
Vercellini, P., Meana, M., Hummelshøj, L., Somigliana, E., Viganò, P., & Fedele, L. (2010) · Reproductive Sciences · doi:10.1177/1933719110382921 · Cited by 76
Self-citationSurgery versus hormonal therapy for deep endometriosis: is it a choice of the physician?
Berlanda, N., Somigliana, E., Frattaruolo, M. P., Buggio, L., Dridi, D., & Vercellini, P. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2016.07.513 · Cited by 74
Self-citationBowel Endometriosis: Current Perspectives on Diagnosis and Treatment
Habib, N., Centini, G., Lazzeri, L., Amoruso, N., Khoury, L. E., Zupi, E., & Afors, K. (2020) · International Journal of Women s Health · doi:10.2147/ijwh.s190326 · Cited by 75
Morotti, M., Remorgida, V., Venturini, P. L., & Ferrero, S. (2014) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2014.05.016 · Cited by 72
Letrozole and norethisterone acetate in rectovaginal endometriosis
Remorgida, V., Abbamonte, L. H., Ragni, N., Fulcheri, E., & Ferrero, S. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2006.12.027 · Cited by 72
Sansone, A., Rosa, N. D., Giampaolino, P., Guida, M., Laganà, A. S., & Carlo, C. D. (2018) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-018-4851-0 · Cited by 68
Ferrero, S., Remorgida, V., Venturini, P. L., & Maggiore, U. L. R. (2013) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2013.11.030 · Cited by 65
A stepped-care approach to symptomatic endometriosis management: A participatory research initiative
Vercellini, P., Donati, A., Ottolini, F., Frassineti, A., Fiorini, J., Nebuloni, V., Frattaruolo, M. P., Roberto, A., Mosconi, P., & Somigliana, E. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.01.037 · Cited by 64
Self-citationDienogest in the treatment of endometriosis
Bizzarri, N., Remorgida, V., Leone Roberti Maggiore, U., Scala, C., Tafi, E., Ghirardi, V., Salvatore, S., Candiani, M., Venturini, P. L., & Ferrero, S. (2014) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2014.943734 · Cited by 63
Role of medical therapy in the management of deep rectovaginal endometriosis
Vercellini, P., Buggio, L., & Somigliana, E. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.08.038 · Cited by 62
Self-citationVercellini, P., Barbara, G., Buggio, L., Frattaruolo, M. P., Somigliana, E., & Fedele, L. (2012) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2012.01.003 · Cited by 67
Self-citationCurrent pharmacotherapy for endometriosis
Ferrero, S., Remorgida, V., & Venturini, P. L. (2010) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656561003685880 · Cited by 60
Barbàra, G., Facchin, F., Meschìa, M., Berlanda, N., Frattaruolo, M. P., & Vercellini, P. (2016) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13031 · Cited by 59
Self-citationFerrero, S., Leone Roberti Maggiore, U., Scala, C., Di Luca, M., Venturini, P. L., & Remorgida, V. (2013) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-012-2581-2 · Cited by 57
Oral and depot progestin therapy for endometriosis: towards a personalized medicine
Buggio, L., Somigliana, E., Barbara, G., Frattaruolo, M. P., & Vercellini, P. (2017) · Expert Opinion on Pharmacotherapy · doi:10.1080/14656566.2017.1381086 · Cited by 58
Self-citationRobotic surgery for deep endometriosis: a paradigm shift
Siesto, G., Iedà, N., Rosati, R., & Vitobello, D. (2013) · International Journal of Medical Robotics and Computer Assisted Surgery · doi:10.1002/rcs.1518 · Cited by 56
Medical Treatment for Endometriosis: Tolerability, Quality of Life and Adherence
Barbàra, G., Buggio, L., Facchin, F., & Vercellini, P. (2021) · Frontiers in Global Women s Health · doi:10.3389/fgwh.2021.729601 · Cited by 60
Self-citationEzzati, M., & Carr, B. R. (2015) · Women s Health · doi:10.2217/whe.14.68 · Cited by 54
Advances in the medical management of bowel endometriosis
Vercellini, P., Sergenti, G., Buggio, L., Frattaruolo, M. P., Dridi, D., & Berlanda, N. (2020) · Best Practice & Research Clinical Obstetrics & Gynaecology · doi:10.1016/j.bpobgyn.2020.06.004 · Cited by 55
Self-citationProgestin Therapy in Endometriosis
Gezer, A., & Oral, E. (2015) · Women s Health · doi:10.2217/whe.15.42 · Cited by 50
Combined Oral Contraceptive Therapy in Women with Posterior Deep Infiltrating Endometriosis
Mabrouk, M., Frascà, C., Geraci, E., Montanari, G., Ferrini, G., Raimondo, D., Alvisi, S., Paradisi, R., Villa, G., & Seracchioli, R. (2011) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2011.04.008 · Cited by 46
Grandi, G., Xholli, A., Napolitano, A., Palma, F., & Cagnacci, A. (2014) · Reproductive Sciences · doi:10.1177/1933719114556488 · Cited by 46
Tarjanne, S., Heikinheimo, O., Mentula, M., & Härkki, P. (2015) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.12515 · Cited by 43
Tarjanne, S., Ng, C. H. M., Manconi, F., Arola, J. T., Mentula, M. J., Maneck, B., Fraser, I. S., & Heikinheimo, O. (2015) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.12652 · Cited by 43
Tolerability considerations for gonadotropin-releasing hormone analogues for endometriosis
Corte, L. D., Barra, F., Mercorio, A., Evangelisti, G., Rapisarda, A. M. C., Ferrero, S., Bifulco, G., & Giampaolino, P. (2020) · Expert Opinion on Drug Metabolism & Toxicology · doi:10.1080/17425255.2020.1789591 · Cited by 44
Morotti, M., Venturini, P. L., Biscaldi, E., Racca, A., Calanni, L., Vellone, V. G., Stabilini, C., & Ferrero, S. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2017.03.033 · Cited by 43
Use of Norethindrone Acetate Alone for Postoperative Suppression of Endometriosis Symptoms
Kaser, D. J., Missmer, S. A., Berry, K. F., & Laufer, M. R. (2012) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2011.09.013 · Cited by 42
Zanetti‐Dällenbach, R., Bartley, J., Müller, C., Schneider, A., & Köhler, C. (2007) · Surgical Endoscopy · doi:10.1007/s00464-007-9560-x · Cited by 42
Mechsner, S., Weichbrodt, M., Riedlinger, W. F. J., Kaufmann, A. M., Schneider, A., & Köhler, C. (2010) · Fertility and Sterility · doi:10.1016/j.fertnstert.2009.03.097 · Cited by 41
Novel drug delivery methods for improving efficacy of endometriosis treatments
Garzon, S., Laganà, A. S., Barra, F., Casarin, J., Cromi, A., Raffaelli, R., Uccella, S., Franchi, M. P., Ghezzi, F., & Ferrero, S. (2020) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2021.1829589 · Cited by 42
Neurotrophines et douleur : étude d’expression et de corrélation dans l’endométriose
Borghese, B., Vaiman, D., Mondon, F., Mbaye, M., Anaf, V., Noël, J.-C., de Ziegler, D., & Chapron, C. (2010) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2010.05.005 · Cited by 39
Tang, H., Lin, T., Wu, M., & Tsai, S. (2024) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12588 · Cited by 42
Donnez, J., Jadoul, P., Colette, S., Luyckx, M., Squifflet, J. P., & Donnez, O. (2012) · Gynecological Surgery · doi:10.1007/s10397-012-0759-z · Cited by 38
Advances in pharmacotherapy for treating endometriosis
Tafi, E., Maggiore, U. L. R., Alessandri, F., Bogliolo, S., Gardella, B., Vellone, V. G., Grillo, F., Mastracci, L., & Ferrero, S. (2015) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656566.2015.1085510 · Cited by 38
Management of endometriosis: Toward value-based, cost-effective, affordable care
Vercellini, P., Facchin, F., Buggio, L., Barbara, G., Berlanda, N., Frattaruolo, M. P., & Somigliana, E. (2018) · Journal of Obstetrics and Gynaecology Canada · doi:10.1016/j.jogc.2017.07.011 · Cited by 36
Self-citationMaggiore, U. L. R., Scala, C., Tafi, E., Racca, A., Biscaldi, E., Vellone, V. G., Venturini, P. L., & Ferrero, S. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.02.106 · Cited by 36
Endometriosis: seeking optimal management in women approaching menopause
ALIO, L., Angioni, S. L., Arena, S., Bartiromo, L., Bergamini, V., Berlanda, N., Bonanni, V., Bonin, C., Buggio, L., Candiani, M., et al. (2019) · Climacteric · doi:10.1080/13697137.2018.1549213 · Cited by 36
Garzon, S., Laganà, A. S., Barra, F., Casarin, J., Cromi, A., Raffaelli, R., Uccella, S., Franchi, M. P., Ghezzi, F., & Ferrero, S. (2020) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2020.1842356 · Cited by 39
The role of progestins in treating the pain of endometriosis
Surrey, E. S. (2006) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2006.06.008 · Cited by 36
Al‐Jefout, M., & Nawaiseh, N. (2015) · Journal of Pediatric and Adolescent Gynecology · doi:10.1016/j.jpag.2015.08.009 · Cited by 39
Female Sexual Function in Women with Suspected Deep Infiltrating Endometriosis
Lima, R. V., Pereira, A. M. G., Beraldo, F. B., Gazzo, C., Martins, J. A., & Lopes, R. G. C. (2018) · Revista Brasileira Ginecologia e Obstetrícia · doi:10.1055/s-0038-1639593 · Cited by 35
How to Manage Bowel Endometriosis: The ETIC Approach
Alabiso, G., ALIO, L., Arena, S., di Prun, A. B., Bergamini, V., Berlanda, N., Busacca, M., Candiani, M., Centini, G., Cello, A. D., et al. (2015) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2015.01.021 · Cited by 34
Self-citation
Metadata
- Authors
- Vercellini, P., Pietropaolo, G., De Giorgi, O., Pasin, R., Chiodini, A., & Crosignani, P. G.
- Affiliations
- University of Milan (IT)
- Corresponding author
- Vercellini, Paolo
- ORCID
- Vercellini, Paolo
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2005-11
- Volume
- 84
- Issue
- 5
- Pages
- 1375-1387
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2062896185
- Cited by
- 197
- References
- 28
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 7 · 2023: 3 · 2022: 5 · 2021: 8 · 2020: 13 · 2019: 6 · 2018: 18 · 2017: 13 · 2016: 9 · 2015: 13 · 2014: 14 · 2013: 9 · 2012: 15
- FWCI
- 6.68
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
- Health Sciences › Medicine › Obstetrics and Gynecology › Gynecological conditions and treatments
- Keywords
- rectovaginal endometriosis, norethindrone acetate, ethinyl estradiol, cyproterone acetate, dysmenorrhea, dyspareunia, dyschezia, treatment satisfaction, lipid profile
- MeSH terms
- Norethindrone Acetate, Adolescent, Adult, Drug Therapy, Combination, Endometriosis, Estrogens, Female, Humans, Middle Aged, Norethindrone, Pain Measurement, Progestins, Rectal Diseases, Vaginal Diseases, Estrogen Replacement Therapy, Confidence Intervals, Statistics, Nonparametric
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
