4-hydroxynonenal-mediated signaling and aging

Aging: a theory based on free radical and radiation chemistry

Harman, D. (1956) · Journal of Gerontology · doi:10.1093/geronj/11.3.298 · Cited by 8,567 · see citing works

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

Esterbauer, H., Schaur, R. J., & Zollner, H. (1991) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(91)90192-6 · Cited by 6,672 · see citing works

Inflamm‐aging: An Evolutionary Perspective on Immunosenescence

FRANCESCHI, C., BONAFÈ, M., VALENSIN, S., OLIVIERI, F., DE LUCA, M., OTTAVIANI, E., & DE BENEDICTIS, G. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06651.x · Cited by 5,358 · see citing works

Mitochondria, Oxidants, and Aging

Balaban, R. S., Nemoto, S., & Finkel, T. (2005) · Cell · doi:10.1016/j.cell.2005.02.001 · Cited by 4,388 · see citing works

Blinded by the Light: The Growing Complexity of p53

Vousden, K. H., & Prives, C. (2009) · Cell · doi:10.1016/j.cell.2009.04.037 · Cited by 3,163 · see citing works

MTOR: a pharmacologic target for autophagy regulation

Kim, Y. C., & Guan, K.-L. (2015) · Journal of Clinical Investigation · doi:10.1172/jci73939 · Cited by 2,126 · see citing works

mTOR is a key modulator of ageing and age-related disease

Johnson, S. C., Rabinovitch, P. S., & Kaeberlein, M. (2013) · Nature · doi:10.1038/nature11861 · Cited by 1,676 · see citing works

Relationship of Interleukin-6 and Tumor Necrosis Factor-  With Muscle Mass and Muscle Strength in Elderly Men and Women: The Health ABC Study

Visser, M., Pahor, M., Taaffe, D. R., Goodpaster, B. H., Simonsick, E. M., Newman, A. B., Nevitt, M., & Harris, T. B. (2002) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/57.5.m326 · Cited by 1,294 · see citing works

Lipid peroxidation: Physiological levels and dual biological effects

Niki, E. (2009) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2009.05.032 · Cited by 1,006 · see citing works

Inflammatory markers in population studies of aging

Singh, T., & Newman, A. B. (2010) · Ageing Research Reviews · doi:10.1016/j.arr.2010.11.002 · Cited by 866 · see citing works

Oxidative stress response and Nrf2 signaling in aging

Zhang, H., Davies, K. J. A., & Forman, H. J. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.05.036 · Cited by 804 · see citing works

The two TORCs and Akt

Bhaskar, P. T., & Hay, N. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.03.020 · Cited by 798 · see citing works

The mTOR pathway in the control of protein synthesis

Wang, X., & Proud, C. G. (2006) · Physiology · doi:10.1152/physiol.00024.2006 · Cited by 778 · see citing works

Stress-activated cap’n’collar transcription factors in aging and human disease

Sykiotis, G. P., & Bohmann, D. (2010) · Science Signaling · doi:10.1126/scisignal.3112re3 · Cited by 776 · see citing works

PI3K/Akt: getting it right matters

Franke, T. F. (2008) · Oncogene · doi:10.1038/onc.2008.313 · Cited by 696 · see citing works

mSin1 Is Necessary for Akt/PKB Phosphorylation, and Its Isoforms Define Three Distinct mTORC2s

Frías, M. A., Thoreen, C. C., Jaffe, J. D., Schroder, W. A., Sculley, T. B., Carr, S. A., & Sabatini, D. M. (2006) · Current Biology · doi:10.1016/j.cub.2006.08.001 · Cited by 690 · see citing works

Is the oxidative stress theory of aging dead?

Pérez, V. I., Bokov, A., Remmen, H. V., Mele, J., Ran, Q., Ikeno, Y., & Richardson, A. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.06.003 · Cited by 604 · see citing works

Role of lipid peroxidation derived 4-hydroxynonenal (4-HNE) in cancer: Focusing on mitochondria

Zhong, H., & Yin, H. (2014) · Redox Biology · doi:10.1016/j.redox.2014.12.011 · Cited by 540 · see citing works

The redox stress hypothesis of aging

Sohal, R. S., & Orr, W. C. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.10.445 · Cited by 473 · see citing works

Markers of Oxidative Stress in Erythrocytes and Plasma During Aging in Humans

Pandey, K. B., & Rizvi, S. I. (2009) · Oxidative Medicine and Cellular Longevity · doi:10.4161/oxim.3.1.10476 · Cited by 444 · see citing works

Redox homeostasis: The Golden Mean of healthy living

Ursini, F., Maiorino, M., & Forman, H. J. (2016) · Redox Biology · doi:10.1016/j.redox.2016.01.010 · Cited by 418 · see citing works

Elevated 4-Hydroxynonenal in Ventricular Fluid in Alzheimer’s Disease

Lovell, M. A., Ehmann, W. D., Mattson, M. P., & Markesbery, W. R. (1997) · Neurobiology of Aging · doi:10.1016/s0197-4580(97)00108-5 · Cited by 413 · see citing works

Lipid peroxidation and neurodegenerative disease

Reed, T. T. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.06.027 · Cited by 380 · see citing works

The TOR pathway comes of age

Stanfel, M. N., Shamieh, L. S., Kaeberlein, M. R., & Kennedy, B. K. (2009) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2009.06.007 · Cited by 339 · see citing works

mTOR signaling in aging and neurodegeneration: at the crossroad between metabolism dysfunction and impairment of autophagy

Perluigi, M., Di Domenico, F., & Butterfield, D. A. (2015) · Neurobiology of Disease · doi:10.1016/j.nbd.2015.03.014 · Cited by 339 · see citing works

Aldehyde dehydrogenase 2 (ALDH2) rescues myocardial ischaemia/reperfusion injury: role of autophagy paradox and toxic aldehyde

Ma, H., Guo, R., Yu, L., Zhang, Y., & Ren, J. T. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq253 · Cited by 336 · see citing works

Inflamm-ageing

Cevenini, E., Monti, D., & Franceschi, C. (2013) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/mco.0b013e32835ada13 · Cited by 317 · see citing works

Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress

Numazawa, S., Ishikawa, M., Yoshida, A., Tanaka, S., & Yoshida, T. (2003) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00043.2003 · Cited by 316 · see citing works

PI3-kinase/Akt/mTOR signaling: Impaired on/off switches in aging, cognitive decline and Alzheimer's disease

Neill, C. O. (2013) · Experimental Gerontology · doi:10.1016/j.exger.2013.02.025 · Cited by 292 · see citing works

NF-κB in Aging and Disease.

Tilstra, J. S., Clauson, C. L., Niedernhofer, L. J., & Robbins, P. D. (2011) · Europe PMC (PubMed Central) · Cited by 290 · see citing works

Increased Lipid Oxidation Causes Oxidative Stress, Increased Peroxisome Proliferator-activated Receptor-γ Expression, and Diminished Pro-osteogenic Wnt Signaling in the Skeleton

Almeida, M., Ambrogini, E., Li, H., Manolagas, S. C., & Jilka, R. L. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.023572 · Cited by 278 · see citing works

The lipid peroxidation product 4-hydroxy-2-nonenal: Advances in chemistry and analysis

Spickett, C. M. (2013) · Redox Biology · doi:10.1016/j.redox.2013.01.007 · Cited by 269 · see citing works

On the role of 4-hydroxynonenal in health and disease

Csala, M., Kardon, T., Legeza, B., Lizák, B., Mandl, J., Margittai, É., Puskás, F., Száraz, P., Szelényi, P., & Bánhegyi, G. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.01.015 · Cited by 244 · see citing works

Age-associated analysis of oxidative stress parameters in human plasma and erythrocytes

Gil, L., Siems, W., Mazurek, B., Gross, J., Schroeder, P., Voss, P., & Grune, T. (2006) · Free Radical Research · doi:10.1080/10715760600592962 · Cited by 242 · see citing works

Markers of oxidant stress that are clinically relevant in aging and age-related disease

Jacob, K. D., Hooten, N. N., Trzeciak, A. R., & Evans, M. K. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.02.008 · Cited by 233 · see citing works

Resveratrol Prevents the Prohypertrophic Effects of Oxidative Stress on LKB1

Dolinsky, V. W., Chan, A. Y. M., Frayne, I. R., Light, P. E., Rosiers, C. D., & Dyck, J. R. B. (2009) · Circulation · doi:10.1161/circulationaha.108.787440 · Cited by 232 · see citing works

4-Hydroxy-nonenal—A Bioactive Lipid Peroxidation Product

Schaur, R. J., Siems, W., Bresgen, N., & Eckl, P. (2015) · Biomolecules · doi:10.3390/biom5042247 · Cited by 231 · see citing works

4-Hydroxynonenal in the Pathogenesis and Progression of Human Diseases

Shoeb, M., Ansari, N., Srivastava, S., & Ramana, K. (2013) · Current Medicinal Chemistry · doi:10.2174/09298673113209990181 · Cited by 230 · see citing works

4-Hydroxy-2-nonenal, a reactive product of lipid peroxidation, and neurodegenerative diseases: a toxic combination illuminated by redox proteomics studies

Perluigi, M., Coccia, R., & Butterfield, D. A. (2012) · Antioxidants & Redox Signaling · doi:10.1089/ars.2011.4406 · Cited by 229 · see citing works

The chemistry of cell signaling by reactive oxygen and nitrogen species and 4-hydroxynonenal

Forman, H. J., Fukuto, J. M., Miller, T., Zhang, H., Rinna, A., & Levy, S. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.06.011 · Cited by 226 · see citing works

Plasma interleukin-6 and soluble IL-6 receptors are associated with psychological well-being in aging women.

Friedman, E. M., Hayney, M., Love, G. D., Singer, B. H., & Ryff, C. D. (2007) · Health Psychology · doi:10.1037/0278-6133.26.3.305 · Cited by 210 · see citing works

4-Hydroxynonenal Induces Adaptive Response and Enhances PC12 Cell Tolerance Primarily through Induction of Thioredoxin Reductase 1 via Activation of Nrf2

Chen, Z.-H., Saito, Y., Yoshida, Y., Sekine, A., Noguchi, N., & Niki, E. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m508556200 · Cited by 197 · see citing works

Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease

Bradley, M. A., Markesbery, W. R., & Lovell, M. A. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.02.016 · Cited by 193 · see citing works

IκB Kinase, a Molecular Target for Inhibition by 4-Hydroxy-2-nonenal

Ji, C., Kozak, K. R., & Marnett, L. J. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101266200 · Cited by 190 · see citing works

Reactive Carbonyl SpeciesIn Vivo: Generation and Dual Biological Effects

Semchyshyn, H. M. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/417842 · Cited by 189 · see citing works

Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway

Zhang, Z., Wang, S., Zhou, S., Yan, X., Wang, Y., Chen, J., Mellen, N. M., Kong, M., Gu, J., Tan, Y., et al. (2014) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2014.09.022 · Cited by 188 · see citing works

4-Hydroxynonenal Prevents NF-κB Activation and Tumor Necrosis Factor Expression by Inhibiting IκB Phosphorylation and Subsequent Proteolysis

Page, S., Fischer, C., Baumgartner, B., Haas, M., Kreusel, U., Loidl, G., Hayn, M., Ziegler‐Heitbrock, H. W. L., Neumeier, D., & Brand, K. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.17.11611 · Cited by 166 · see citing works

Nrf2-regulated phase II enzymes are induced by chronic ambient nanoparticle exposure in young mice with age-related impairments

Zhang, H., Liu, H., Davies, K. J. A., Sioutas, C., Finch, C. E., Morgan, T. E., & Forman, H. J. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.02.042 · Cited by 155 · see citing works

4-Hydroxynonenal and cholesterol oxidation products in atherosclerosis

Leonarduzzi, G., Chiarpotto, E., Biasi, F., & Poli, G. (2005) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.200500090 · Cited by 152 · see citing works

4-Hydroxynonenal triggers an epidermal growth factor receptor-linked signal pathway for growth inhibition

Liu, W., Akhand, A. A., Kato, M., Yokoyama, I., Miyata, T., Kurokawa, K., Uchida, K., & Nakashima, I. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.14.2409 · Cited by 149 · see citing works

Aldose Reductase Mediates the Lipopolysaccharide-induced Release of Inflammatory Mediators in RAW264.7 Murine Macrophages

Ramana, K. V., Fadl, A. A., Tammali, R., Reddy, A. B. M., Chopra, A. K., & Sk, S. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m603819200 · Cited by 145 · see citing works

Activation of EGF receptor by oxidized LDL

Suc, I., Meilhac, O., Lajoie‐Mazenc, I., Vandaele, J., Jürgens, G., Salvayre, R., & Nègre‐Salvayre, A. (1998) · The FASEB Journal · doi:10.1096/fasebj.12.9.665 · Cited by 140 · see citing works

Reactive aldehydes – second messengers of free radicals in diabetes mellitus

Jaganjac, M., Tirosh, O., Cohen, G., Sasson, S., & Žarković, N. (2013) · Free Radical Research · doi:10.3109/10715762.2013.789136 · Cited by 137 · see citing works

mTOR and autophagy in normal brain aging and caloric restriction ameliorating age-related cognition deficits

Yang, F., Chu, X., Yin, M., Liu, X., Yuan, H., Niu, Y., & Fu, L. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.02.005 · Cited by 136 · see citing works

A recollection of mTOR signaling in learning and memoryPreprint

Graber, T. E., McCamphill, P. K., & Sossin, W. S. (2013) · Learning & Memory · doi:10.1101/lm.027664.112 · Cited by 135 · see citing works

Relationship of electrophilic stress to aging

Zimniak, P. (2011) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2011.05.039 · Cited by 133 · see citing works

p21 Both Attenuates and Drives Senescence and Aging in BubR1 Progeroid Mice

Baker, D. J., Weaver, R. L., & van Deursen, J. M. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.03.028 · Cited by 130 · see citing works

4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells

Sharma, A., Sharma, R., Chaudhary, P., Vatsyayan, R., Pearce, V. P., Jeyabal, P., Zimniak, P., Awasthi, S., & Awasthi, S. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.09.016 · Cited by 104 · see citing works

HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells

Iles, K. E., Dickinson, D. A., Wigley, A. F., Welty, N. E., Blank, V., & Forman, H. J. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.03.026 · Cited by 103 · see citing works

4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase

Vaillancourt, F., Fahmi, H., Shi, Q., Lavigne, P., Ranger, P., Fernandes, J., & Benderdour, M. (2008) · Arthritis Research & Therapy · doi:10.1186/ar2503 · Cited by 102 · see citing works

FALDH Reverses the Deleterious Action of Oxidative Stress Induced by Lipid Peroxidation Product 4-Hydroxynonenal on Insulin Signaling in 3T3-L1 Adipocytes

Demozay, D., Mas, J.-C., Rocchi, S., & OBBERGHEN, E. V. (2008) · Diabetes · doi:10.2337/db07-0389 · Cited by 101 · see citing works

Aging-Associated Dysfunction of Akt/Protein Kinase B: S-Nitrosylation and Acetaminophen Intervention

Wu, M., Katta, A., Gadde, M. K., Liu, H., Kakarla, S. K., Fannin, J. C., Paturi, S., Arvapalli, R. K., Rice, K. M., Wang, Y., et al. (2009) · PLoS ONE · doi:10.1371/journal.pone.0006430 · Cited by 97 · see citing works

Protein phosphatase 2A-linked and -unlinked caspase-dependent pathways for downregulation of Akt kinase triggered by 4-hydroxynonenal

Liu, W., Akhand, A. A., Takeda, K., Kawamoto, Y., Itoigawa, M., Kato, M., Suzuki, H., Ishikawa, N., & Nakashima, I. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401238 · Cited by 97 · see citing works

Link between PI3K/AKT/PTEN Pathway and NOX Proteinin Diseases

Nakanishi, A. (2014) · Aging and Disease · doi:10.14336/ad.2014.0500203 · Cited by 95 · see citing works

Proteasomal dysfunction induced by 4‐hydroxy‐2,3‐trans‐nonenal, an end‐product of lipid peroxidation: a mechanism contributing to neurodegeneration?

Hyun, D., Lee, M., Halliwell, B. B., & Jenner, P. G. (2002) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2002.01125.x · Cited by 93 · see citing works

4-Hydroxynonenal enhances MMP-2 production in vascular smooth muscle cells via mitochondrial ROS-mediated activation of the Akt/NF-κB signaling pathways

Lee, S. J., Seo, K. W., Yun, M. R., Bae, S. S., Lee, W. S., Hong, K. W., & Kim, C. D. (2008) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2008.08.022 · Cited by 91 · see citing works

4-Hydroxynonenal induces apoptosis, NF-κB-activation and formation of 8-isoprostane in vascular smooth nmuscle cells

Ruef, J., Moser, M., Bode, C., Kübler, W., & Runge, M. S. (2001) · Basic Research in Cardiology · doi:10.1007/s003950170064 · Cited by 87 · see citing works

Calorie restriction delays lipid oxidative damage in Drosophila melanogaster

Zheng, J., Mutcherson, R. J., & Helfand, S. L. (2005) · Aging Cell · doi:10.1111/j.1474-9726.2005.00159.x · Cited by 83 · see citing works

4-Hydroxynonenal and PPARγ ligands affect proliferation, differentiation, and apoptosis in colon cancer cells

Cerbone, A., Toaldo, C., Laurora, S., Briatore, F., Pizzimenti, S., Dianzani, M. U., Ferretti, C., & Barrera, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.02.009 · Cited by 82 · see citing works

Modification of Akt2 by 4-Hydroxynonenal Inhibits Insulin-Dependent Akt Signaling in HepG2 Cells

Shearn, C. T., Fritz, K. S., Reigan, P., & Petersen, D. R. (2011) · Biochemistry · doi:10.1021/bi200029w · Cited by 73 · see citing works

Oxidized LDL and 4-hydroxynonenal modulate tyrosine kinase receptor activity

Nègre‐Salvayre, A., Vieira, O. V., Escargueil‐Blanc, I., & Salvayre, R. (2003) · Molecular Aspects of Medicine · doi:10.1016/s0098-2997(03)00020-7 · Cited by 70 · see citing works

The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor κB in neurons

Camandola, S., Poli, G., & Mattson, M. P. (2000) · Molecular Brain Research · doi:10.1016/s0169-328x(00)00234-5 · Cited by 68 · see citing works

Submicromolar concentrations of 4-hydroxynonenal induce glutamate cysteine ligase expression in HBE1 cells

Zhang, H., Court, N., & Forman, H. J. (2007) · Redox Report · doi:10.1179/135100007x162266 · Cited by 67 · see citing works

Elevated levels of 4-hydroxynonenal-histidine Michael adduct in the hippocampi of patients with Alzheimer's disease

Fukuda, M., Kanou, F., Shimada, N., Sawabe, M., Saito, Y., Murayama, S., Hashimoto, M., Maruyama, N., & Ishigami, A. (2009) · Biomedical Research · doi:10.2220/biomedres.30.227 · Cited by 66 · see citing works

4-Hydroxynonenal modulation of p53 family gene expression in the SK-N-BE neuroblastoma cell line

Laurora, S., Tamagno, E., Briatore, F., Bardini, P., Pizzimenti, S., Toaldo, C., Reffo, P., Costelli, P., Dianzani, M. U., Danni, O., et al. (2004) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2004.10.014 · Cited by 65 · see citing works

High-Density Lipoproteins Prevent the Oxidized Low-Density Lipoprotein–Induced Endothelial Growth Factor Receptor Activation and Subsequent Matrix Metalloproteinase-2 Upregulation

Robbesyn, F., Augè, N., Vindis, C., Cantéro, A., Barbaras, R., Nègre‐Salvayre, A., & Salvayre, R. (2005) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000164805.73558.80 · Cited by 65 · see citing works

Signaling pathways involved in phase II gene induction by α, β-unsaturated aldehydes

Zhang, H., & Forman, H. J. (2009) · Toxicology and Industrial Health · doi:10.1177/0748233709102209 · Cited by 64 · see citing works

Interaction between 4-Hydroxy-2,3-alkenals and the Platelet-derived Growth Factor-β Receptor

Robino, G., Parola, M., Marra, F., Caligiuri, A., Franco, R. D., Zamara, E., Bellomo, G., Geñtilini, P., Pinzani, M., & Dianzani, M. U. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m007694200 · Cited by 63 · see citing works

Reactive Lipid Species from Cyclooxygenase-2 Inactivate Tumor Suppressor LKB1/STK11

Wagner, T. M., Mullally, J. E., & Fitzpatrick, F. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m509723200 · Cited by 62 · see citing works

Involvement of reactive oxygen species in cyclic stretch‐induced NF‐κB activation in human fibroblast cells

Amma, H., Naruse, K., Ishiguro, N., & Sokabe, M. (2005) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0706182 · Cited by 62 · see citing works

Mildly Oxidized LDL Induces Activation of Platelet-Derived Growth Factor β-Receptor Pathway

Escargueil‐Blanc, I., Salvayre, R., Vacaresse, N., Jürgens, G., Darblade, B., Arnal, J., Parthasarathy, S., & Nègre‐Salvayre, A. (2001) · Circulation · doi:10.1161/hc4001.097179 · Cited by 61 · see citing works

γ-Glutamyl transpeptidase is induced by 4-hydroxynonenal via EpRE/Nrf2 signaling in rat epithelial type II cells

Zhang, H., Liu, H., Dickinson, D. A., Liu, R.-M., Postlethwait, E. M., Laperche, Y., & Forman, H. J. (2005) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2005.11.005 · Cited by 60 · see citing works

Protein modification by oxidized phospholipids and hydrolytically released lipid electrophiles: Investigating cellular responses

Cantu, J. C., & Marnett, L. J. (2012) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/j.bbamem.2012.04.014 · Cited by 60 · see citing works

4-Hydroxynonenal Induces Rat γ-Glutamyl Transpeptidase through Mitogen-Activated Protein Kinase–Mediated Electrophile Response Element/Nuclear Factor Erythroid 2–Related Factor 2 Signaling

Zhang, H., Liu, H., Iles, K. E., Liu, R.-M., Postlethwait, E. M., Laperche, Y., & Forman, H. J. (2005) · American Journal of Respiratory Cell and Molecular Biology · doi:10.1165/rcmb.2005-0280oc · Cited by 59 · see citing works

Akt/protein kinase B in skeletal muscle physiology and pathology

Wu, M., Falasca, M., & Blough, E. R. (2010) · Journal of Cellular Physiology · doi:10.1002/jcp.22353 · Cited by 58 · see citing works

Increased 4-Hydroxynonenal Formation Contributes to Obesity-Related Lipolytic Activation in Adipocytes

Zhang, X., Wang, Z., Li, J., Gu, D., Li, S., Shen, C., & Song, Z. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070663 · Cited by 56 · see citing works

Differential regulation of cyclooxygenase‐2 and inducible nitric oxide synthase by 4‐hydroxynonenal in human osteoarthritic chondrocytes through ATF‐2/CREB‐1 transactivation and concomitant inhibition of NF‐κB signaling cascade

Vaillancourt, F., Morquette, B., Shi, Q., Fahmi, H., Lavigne, P., Battista, J. A. D., Fernandes, J., & Benderdour, M. (2006) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21110 · Cited by 55 · see citing works

4-Hydroxynonenal Induces G2/M Phase Cell Cycle Arrest by Activation of the Ataxia Telangiectasia Mutated and Rad3-related Protein (ATR)/Checkpoint Kinase 1 (Chk1) Signaling Pathway

Chaudhary, P., Sharma, R., Sahu, M., Vishwanatha, J. K., Awasthi, S., & Awasthi, Y. C. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.467662 · Cited by 55 · see citing works

Immunosenescence comes of age

Pawelec, G. (2007) · EMBO Reports · doi:10.1038/sj.embor.7400922 · Cited by 54 · see citing works

Inhibition of NF-κB Activation by 4-Hydroxynonenal Contributes to Liver Injury in a Mouse Model of Alcoholic Liver Disease

Dou, X., Li, S., Wang, Z., Gu, D., Shen, C., Yao, T., & Song, Z. (2012) · American Journal Of Pathology · doi:10.1016/j.ajpath.2012.08.004 · Cited by 52 · see citing works

Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN) Inhibition by 4-Hydroxynonenal Leads to Increased Akt Activation in Hepatocytes

Shearn, C. T., McCullough, R. L., Stewart, B. J., Fritz, K. S., Galligan, J. J., Hail, N., & Petersen, D. R. (2011) · Molecular Pharmacology · doi:10.1124/mol.110.069534 · Cited by 51 · see citing works

Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells

Kaarniranta, K., Ryhänen, T., Karjalainen, H. M., Lammi, M. J., Suuronen, T., Huhtala, A., Kontkanen, M., Teräsvirta, M. E., Uusitalo, H. M. T., & Salminen, A. (2005) · Neuroscience Letters · doi:10.1016/j.neulet.2005.03.009 · Cited by 47 · see citing works

Role of Lipid Aldehydes in Cataractogenesis: 4-Hydroxynonenal-Induced Cataract

Ansari, N. H., Wang, L., & Sk, S. (1996) · Biochemical and Molecular Medicine · doi:10.1006/bmme.1996.0028 · Cited by 46 · see citing works

Circulating 4-hydroxynonenal–protein thioether adducts assessed by gas chromatography–mass spectrometry are increased with disease progression and aging in spontaneously hypertensive rats

Asselin, C., Bouchard, B., Tardif, J., & Rosiers, C. D. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.03.011 · Cited by 46 · see citing works

Even stressed cells are individuals: second messengers of free radicals in pathophysiology of cancer

Jaganjac, M., Čaćev, T., Gašparović, A. Č., Kapitanović, S., Gall‐Tros̆elj, K., & Žarković, N. (2012) · Croatian Medical Journal · doi:10.3325/cmj.2012.53.304 · Cited by 45 · see citing works

Measurement of 4-hydroxynonenal in small volume blood plasma samples: modification of a gas chromatographic–mass spectrometric method for clinical settings

Spies-Martin, D., Sommerburg, O., Langhans, C., & Leichsenring, M. (2002) · Journal of Chromatography B · doi:10.1016/s1570-0232(02)00242-8 · Cited by 44 · see citing works

The lipid peroxidation product 4-hydroxy-trans-2-nonenal causes protein synthesis in cardiac myocytes via activated mTORC1–p70S6K–RPS6 signaling

Calamaras, T. D., Lee, C., Lan, F., Ido, Y., Siwik, D. A., & Colucci, W. S. (2015) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2015.01.007 · Cited by 43 · see citing works

Regulation of glycogen synthase kinase‐3β by products of lipid peroxidation in human neuroblastoma cells

Dozza, B., Smith, M. A., Perry, G. L., Tabaton, M., & Strocchi, P. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02413.x · Cited by 43 · see citing works

Inhibition of Hydrogen peroxide signaling by 4-hydroxynonenal due to differential regulation of Akt1 and Akt2 contributes to decreases in cell survival and proliferation in hepatocellular carcinoma cells

Shearn, C. T., Reigan, P., & Petersen, D. R. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.04.021 · Cited by 42 · see citing works

Proteomic Analysis of Nitrated and 4-Hydroxy-2-Nonenal-Modified Serum Proteins During Aging

Kim, C. H., Zou, Y., Kim, D. H., Kim, N. D., Yu, B., & Chung, H. Y. (2006) · The Journals of Gerontology Series A · doi:10.1093/gerona/61.4.332 · Cited by 40 · see citing works

Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells

Vatsyayan, R., Chaudhary, P., Sharma, A., Sharma, R., Lelsani, P. C. R., Awasthi, S., & Awasthi, S. (2010) · Experimental Eye Research · doi:10.1016/j.exer.2010.11.010 · Cited by 39 · see citing works

The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard

Zheng, R., Po, I., Mishin, V. M., Black, A. T., Heck, D. E., Laskin, D. L., Sinko, P. J., Gerecke, D. R., Gordon, M. K., & Laskin, J. D. (2013) · Toxicology and Applied Pharmacology · doi:10.1016/j.taap.2013.06.025 · Cited by 39 · see citing works

Phenolic antioxidants trolox and caffeic acid modulate the oxidized LDL‐induced EGF‐receptor activation

Vacaresse, N., Vieira, O. V., Robbesyn, F., Jürgens, G., Salvayre, R., & Nègre‐Salvayre, A. (2001) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0703981 · Cited by 39 · see citing works

Lipid oxidation products and oxidized low-density lipoproteins impair platelet-derived growth factor receptor activity in smooth muscle cells: implication in atherosclerosis

Vindis, C., Escargueil‐Blanc, I., Uchida, K., Elbaz, M., Salvayre, R., & Nègre‐Salvayre, A. (2007) · Redox Report · doi:10.1179/135100007x162248 · Cited by 37 · see citing works

4-Hydroxynonenal Prevents NO Production in Vascular Smooth Muscle Cells by Inhibiting Nuclear Factor-κB–Dependent Transcriptional Activation of Inducible NO Synthase

Hattori, Y., Hattori, S., & Kasai, K. (2001) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/hq0701.092135 · Cited by 37 · see citing works

Chlamydia pneumoniae activates IKK/IκB-mediated signaling, which is inhibited by 4-HNE and following primary exposure

Donath, B., Fischer, C., Page, S., Prebeck, S., Jilg, N., Weber, M., da Costa, C., Neumeier, D., Miethke, T., & Brand, K. (2002) · Atherosclerosis · doi:10.1016/s0021-9150(02)00198-3 · Cited by 36 · see citing works

4-Hydroxynonenal, a lipid peroxidation product of dietary polyunsaturated fatty acids, has anticarcinogenic properties in colon carcinoma cell lines through the inhibition of telomerase activity

Pizzimenti, S., Menegatti, E., Berardi, D., Toaldo, C., Pettazzoni, P., Minelli, R., Giglioni, B., Cerbone, A., Dianzani, M. U., Ferretti, C., et al. (2009) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2009.06.005 · Cited by 33 · see citing works

Chronic acetaminophen attenuates age-associated increases in cardiac ROS and apoptosis in the Fischer Brown Norway rat

Kakarla, S. K., Fannin, J. C., Keshavarzian, S., Katta, A., Paturi, S., Nalabotu, S. K., Wu, M., Rice, K. M., Manzoor, K., Walker, E. M., et al. (2010) · Basic Research in Cardiology · doi:10.1007/s00395-010-0094-3 · Cited by 31 · see citing works

Inhibition of the Lipopolysaccharide-Induced Stimulation of the Members of the MAPK Family in Human Monocytes/Macrophages by 4-Hydroxynonenal, a Product of Oxidized Omega-6 Fatty Acids

Marantos, C., Mukaro, V. R., Ferrante, J. V., Hii, C. S. T., & Ferrante, A. (2008) · American Journal Of Pathology · doi:10.2353/ajpath.2008.071150 · Cited by 31 · see citing works

4-Hydroxy-2-nonenal Induces Apoptosis by Inhibiting AKT Signaling in Human Osteosarcoma Cells

Ji, G., Yu, N., Xue, X., & Li, Z.-G. (2014) · The Scientific World JOURNAL · doi:10.1155/2014/873525 · Cited by 30 · see citing works

Differential roles of AMPKα1 and AMPKα2 in regulating 4-HNE-induced RPE cell death and permeability

Qin, S., & Rodrigues, G. A. (2010) · Experimental Eye Research · doi:10.1016/j.exer.2010.10.007 · Cited by 29 · see citing works

4-Hydroxynonenal impairs transforming growth factor-β1-induced elastin synthesis via epidermal growth factor receptor activation in human and murine fibroblasts

Larroque-Cardoso, P., Mucher, E., Grazide, M.-H., Josse, G., Schmitt, A.-M., Nadal-Wollbold, F., Žarković, K., Salvayre, R., & Nègre‐Salvayre, A. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.02.015 · Cited by 28 · see citing works

Post-translational Modification of Serine/Threonine Kinase LKB1 via Adduction of the Reactive Lipid Species 4-Hydroxy-trans-2-nonenal (HNE) at Lysine Residue 97 Directly Inhibits Kinase Activity

Calamaras, T. D., Lee, C., Lan, F., Ido, Y., Siwik, D. A., & Colucci, W. S. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.385831 · Cited by 26 · see citing works

Survival responses to oxidative stress and aging

Miura, Y., & Endo, T. (2010) · Geriatrics and gerontology international/Geriatrics & gerontology international · doi:10.1111/j.1447-0594.2010.00597.x · Cited by 26 · see citing works

Aging influences multiple indices of oxidative stress in the heart of the Fischer 344/NNia × Brown Norway/BiNia rat

Asano, S., Rice, K. M., Kakarla, S. K., Katta, A., Desai, D. H., Walker, E. M., Wehner, P. S., & Blough, E. R. (2007) · Redox Report · doi:10.1179/135100007x200254 · Cited by 25 · see citing works

Inhibitory action of salicylideneamino-2-thiophenol on NF-κB signaling cascade and cyclooxygenase-2 in HNE-treated endothelial cells

Park, S., Sung, B., Jang, E. J., Kim, D. H., Park, C. H., Choi, Y. J., Ha, Y. M., Kim, M. K., Kim, N. D., Yu, B. P., et al. (2013) · Archives of Pharmacal Research · doi:10.1007/s12272-013-0116-4 · Cited by 21 · see citing works

The lipid peroxidation end-product and oxidant 4-hydroxynonenal induces insulin resistance in rat slow-twitch skeletal muscle

Prasannarong, M., Santos, F. R., Hooshmand, P., Hooshmand, P., Giovannini, F. J., & Henriksen, E. J. (2013) · Archives of Physiology and Biochemistry · doi:10.3109/13813455.2013.834937 · Cited by 12 · see citing works

Dehydroepiandrosterone effects on Akt signaling modulation in central nervous system of young and aged healthy rats

Janner, D. D. R., Jacob, M., Jahn, M. P., Kucharski, L. C., & Ribeiro, M. F. M. (2010) · The Journal of Steroid Biochemistry and Molecular Biology · doi:10.1016/j.jsbmb.2010.07.006 · Cited by 11 · see citing works

[The role of 4-hydroxynonenal in assessment of chronic obstructive pulmonary disease severity].

Liu, H., & Xu, J. (2012) · PubMed · Cited by 8 · see citing works

The balance between 4‐hydroxynonenal and intrinsic glutathione/glutathione S‐transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas

Uno, K., Kato, K., Kusaka, G., Asano, N., Iijima, K., & Shimosegawa, T. (2011) · Molecular Carcinogenesis · doi:10.1002/mc.20699 · Cited by 6 · see citing works

IL-6 immunoreactivity changes during aging in the polychaete Ophryotrocha labronica (Polychaeta: Dorvilleidae)

Franchini, A., & Ottaviani, E. (2007) · Tissue and Cell · doi:10.1016/j.tice.2006.11.001 · Cited by 3 · see citing works

Reactive oxygen species (ROS) as pleiotropic physiological signalling agents

Sies, H., & Jones, D. P. (2020) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-020-0230-3 · Cited by 5,335 · see citing works

Targeting oxidative stress in disease: Promise and limitations of antioxidant therapy

Forman, H. J., & Zhang, H. (2021) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00233-1 · Cited by 2,900 · see citing works

Protein oxidation - Formation mechanisms, detection and relevance as biomarkers in human diseases

Kehm, R., Baldensperger, T., Raupbach, J., & Höhn, A. (2021) · Redox Biology · doi:10.1016/j.redox.2021.101901 · Cited by 348 · see citing works

Phospholipids and cholesterol: Inducers of cancer multidrug resistance and therapeutic targets

Kopecka, J., Trouillas, P., Gašparović, A. Č., Gazzano, E., Assaraf, Y. G., & Riganti, C. (2019) · Drug Resistance Updates · doi:10.1016/j.drup.2019.100670 · Cited by 296 · see citing works

Antioxidant activity of nanomaterials

Valgimigli, L., Baschieri, A., & Amorati, R. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb00107c · Cited by 264 · see citing works

Physiological Signaling Functions of Reactive Oxygen Species in Stem Cells: From Flies to Man

Sinenko, S. A., Starkova, T. Y., Kuzmin, A. A., & Tomilin, A. N. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.714370 · Cited by 256 · see citing works

Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging

Lapenna, D. (2023) · Ageing Research Reviews · doi:10.1016/j.arr.2023.102066 · Cited by 239 · see citing works

Antioxidant Therapeutic Strategies for Cardiovascular Conditions Associated with Oxidative Stress

Farías, J. G., Molina, V. M., Carrasco, R. A., Zepeda, A. B., Figueroa, E., Letelier, P. J., & Castillo, R. L. (2017) · Nutrients · doi:10.3390/nu9090966 · Cited by 195 · see citing works

Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases

Li, Y., Zhao, T., Li, J., Xia, M., Li, Y., Wang, X., Liu, C., Zheng, T., Chen, R., Kan, D., et al. (2022) · Journal of Immunology Research · doi:10.1155/2022/2233906 · Cited by 185 · see citing works

Lipid (per) oxidation in mitochondria: an emerging target in the ageing process?

Ademowo, O. S., Dias, H. K. I., Burton, D. G. A., & Griffiths, H. R. (2017) · Biogerontology · doi:10.1007/s10522-017-9710-z · Cited by 184 · see citing works

Redox theory of aging: implications for health and disease

Go, Y., & Jones, D. P. (2017) · Clinical Science · doi:10.1042/cs20160897 · Cited by 173 · see citing works

Potential Adverse Public Health Effects Afforded by the Ingestion of Dietary Lipid Oxidation Product Toxins: Significance of Fried Food Sources

Grootveld, M. C., Percival, B. C., Leenders, J., & Wilson, P. (2020) · Nutrients · doi:10.3390/nu12040974 · Cited by 160 · see citing works

Oxidative stress and regeneration

Jaganjac, M., Milković, L., Žarković, N., & Žarković, K. (2022) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2022.02.004 · Cited by 154 · see citing works

Connecting the “Dots”: From Free Radical Lipid Autoxidation to Cell Pathology and Disease

Foret, M. K., Lincoln, R., Carmo, S. D., Cuello, A. C., & Cosa, G. (2020) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00761 · Cited by 144 · see citing works

Lipid Oxidation Derived Aldehydes and Oxysterols Between Health and Disease

Sottero, B., Leonarduzzi, G., Testa, G., Gargiulo, S., Poli, G., & Biasi, F. (2018) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201700047 · Cited by 137 · see citing works

Origin and pathophysiology of protein carbonylation, nitration and chlorination in age-related brain diseases and aging

Gonos, E. S., Καπετάνου, Μ., Sereikaitė, J., Bartosz, G., Naparło, K., Grzesik, M., & Sadowska‐Bartosz, I. (2018) · Aging · doi:10.18632/aging.101450 · Cited by 133 · see citing works

The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases

Jaganjac, M., Milković, L., Gęgotek, A., Cindrić, M., Žarković, K., Skrzydlewska, E., & Žarković, N. (2019) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2019.11.023 · Cited by 114 · see citing works

Mitochondrial Dysfunction: A Key Player in Brain Aging and Diseases

Bartman, S., Coppotelli, G., & Ross, J. M. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46030130 · Cited by 101 · see citing works

Involvement of 4‐hydroxy‐2‐nonenal in pollution‐induced skin damage

Pecorelli, A., Woodby, B. L., Prieux, R., & Valacchi, G. (2019) · BioFactors · doi:10.1002/biof.1513 · Cited by 88 · see citing works

Lipid peroxidation: Reactive carbonyl species, protein/DNA adducts, and signaling switches in oxidative stress and cancer

Moldogazieva, N. T., Zavadskiy, S. P., Astakhov, D. V., & Terentiev, A. A. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.149167 · Cited by 82 · see citing works

Yin-Yang Mechanisms Regulating Lipid Peroxidation of Docosahexaenoic Acid and Arachidonic Acid in the Central Nervous System

Yang, B., Fritsche, K. L., Beversdorf, D. Q., Gu, Z., Lee, J. C., Folk, W. R., Greenlief, C. M., & Sun, G. Y. (2019) · Frontiers in Neurology · doi:10.3389/fneur.2019.00642 · Cited by 74 · see citing works

The role of reactive oxygen species in bone cell physiology and pathophysiology

Marques-Carvalho, A., Kim, H., & Almeida, M. (2023) · Bone Reports · doi:10.1016/j.bonr.2023.101664 · Cited by 72 · see citing works

Electrophilic Aldehyde 4-Hydroxy-2-Nonenal Mediated Signaling and Mitochondrial Dysfunction

Sharma, S., Sharma, P., Bailey, T., Bhattarai, S., Subedi, U., Miller, C., Ara, H., Kidambi, S., Sun, H., Panchatcharam, M., et al. (2022) · Biomolecules · doi:10.3390/biom12111555 · Cited by 67 · see citing works

Lipid peroxidation products’ role in autophagy regulation

Gęgotek, A., & Skrzydlewska, E. (2024) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2024.01.001 · Cited by 53 · see citing works

Phospholipid peroxidation inhibits autophagy via stimulating the delipidation of oxidized LC3-PE

Li, W., Luo, L., Zhou, Q., Gong, H., Fu, Y., Yan, C., Li, E., Sun, J. Y., Luo, Z., Ding, Z., et al. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102421 · Cited by 42 · see citing works

Oxidative stress, lipid peroxidation and premature placental senescence in preeclampsia

Nègre‐Salvayre, A., Swiader, A., Salvayre, R., & Guerby, P. (2022) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2022.109416 · Cited by 46 · see citing works

Intracellular second messengers mediate stress inducible hormesis and Programmed Cell Death: A review

Zhou, D. R., Eid, R., Miller, K. A., Boucher, É. L., Mandato, C. A., & Greenwood, M. T. (2019) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2019.01.016 · Cited by 43 · see citing works

4-Hydroxy-2-nonenal in food products: A review of the toxicity, occurrence, mitigation strategies and analysis methods

Liao, H., Zhu, M., & Chen, Y. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.12.011 · Cited by 42 · see citing works

Lipid Peroxidation Linking Diabetes and Cancer: The Importance of 4-Hydroxynonenal

Jaganjac, M., & Žarković, N. (2022) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0146 · Cited by 39 · see citing works

Oxidative Stress-mediated Lipid Peroxidation-derived Lipid Aldehydes in the Pathophysiology of Neurodegenerative Diseases

Allowitz, K. V., Taylor, J., Harames, K., Yoo, J., Baloch, O. A., & Ramana, K. V. (2024) · Current Neuropharmacology · doi:10.2174/011570159x342720241014164650 · Cited by 38 · see citing works

Ferroptosis in idiopathic pulmonary fibrosis: mechanisms, impact, and therapeutic opportunities

Yao, M., Liu, Z., Zhao, W., Song, S., Huang, X., & Wang, Y. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1567994 · Cited by 47 · see citing works

4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation

Valacchi, G., Pecorelli, A., Cervellati, C., & Hayek, J. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2016.12.045 · Cited by 37 · see citing works

Ozone in the adjunct medical treatment. The round personality of a molecule with hormetic properties

Chirumbolo, S., Tirelli, U., Franzini, M., Pandolfi, S., Ricevuti, G., Vaiano, F., & Valdenassi, L. (2023) · Human & Experimental Toxicology · doi:10.1177/09603271231218926 · Cited by 34 · see citing works

Reduced Liver Autophagy in High-Fat Diet Induced Liver Steatosis in New Zealand Obese Mice

Korovila, I., Höhn, A., Jung, T., Grune, T., & Ott, C. (2021) · Antioxidants · doi:10.3390/antiox10040501 · Cited by 31 · see citing works

4-Hydroxynonenal Contributes to Fibroblast Senescence in Skin Photoaging Evoked by UV-A Radiation

Swiader, A., Camaré, C., Guerby, P., Salvayre, R., & Nègre‐Salvayre, A. (2021) · Antioxidants · doi:10.3390/antiox10030365 · Cited by 29 · see citing works

Nanoantioxidants: The Fourth Generation of Antioxidants—Recent Research Roadmap and Future Perspectives

Shah, S. T., Chowdhury, Z. Z., Simarani, K., Basirun, W. J., Badruddin, I. A., Hussien, M., Alrobei, H., & Kamangar, S. (2022) · Coatings · doi:10.3390/coatings12101568 · Cited by 28 · see citing works

Improving Sperm Oxidative Stress and Embryo Quality in Advanced Paternal Age Using Idebenone In Vitro—A Proof-of-Concept Study

Nikitaras, V., Zander‐Fox, D., & McPherson, N. O. (2021) · Antioxidants · doi:10.3390/antiox10071079 · Cited by 28 · see citing works

Study of Carnosine’s effect on nude mice skin to prevent UV-A damage

Radrezza, S., Carini, M., Baron, G., Aldini, G., Nègre‐Salvayre, A., & D’Amato, A. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.07.010 · Cited by 29 · see citing works

Is carbonyl/AGE/RAGE stress a hallmark of the brain aging?

Semchyshyn, H. M. (2021) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-021-02529-y · Cited by 27 · see citing works

Long chain lipid hydroperoxides increase the glutathione redox potential through glutathione peroxidase 4

Corteselli, E., Gibbs-Flournoy, E. A., Simmons, S. O., Bromberg, P. A., Gold, A. R., & Samet, J. M. (2019) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2019.03.002 · Cited by 29 · see citing works

Telomere length is independently associated with age, oxidative biomarkers, and sport training in skeletal muscle of healthy adult males

Magi, F., Dimauro, I., Margheritini, F., Duranti, G., Mercatelli, N., Fantini, C., Ripani, F. R., Sabatini, S., & Caporossi, D. (2018) · Free Radical Research · doi:10.1080/10715762.2018.1459043 · Cited by 26 · see citing works

Oxidative Stress Dysregulates Protein Homeostasis Within the Male Germ Line

Cafe, S. L., Nixon, B., Dun, M. D., Roman, S. D., Bernstein, I. R., & Bromfield, E. G. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7832 · Cited by 27 · see citing works

Investigation of ROS scavenging properties and in vitro cytotoxicity of oxygen-deficient La2O3-x nanostructure synthesized by spray pyrolysis method

Rehman, Y., Copet, C., Morlando, A., Huang, X., & Konstantinov, K. (2020) · Journal of nanostructure in chemistry · doi:10.1007/s40097-020-00356-8 · Cited by 23 · see citing works

Reactive oxygen species in health and disease

Ren, Y., Li, J., & Dai, X. (2026) · Molecular Biomedicine · doi:10.1186/s43556-026-00419-2 · Cited by 26 · see citing works

NXP032 Ameliorates Aging-Induced Oxidative Stress and Cognitive Impairment in Mice through Activation of Nrf2 Signaling

Lee, J. M., Lee, J. H., Song, M. K., & Kim, Y. (2022) · Antioxidants · doi:10.3390/antiox11010130 · Cited by 21 · see citing works

Age-related alteration in HNE elimination enzymes

Zhang, H., Morgan, T. E., & Forman, H. J. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108749 · Cited by 20 · see citing works

Does membrane curvature elastic energy play a role in mediating oxidative stress in lipid membranes?

Bahja, J., & Dymond, M. K. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.05.021 · Cited by 19 · see citing works

Reactive Carbonyl Species and Protein Lipoxidation in Atherogenesis

Nègre‐Salvayre, A., & Salvayre, R. (2024) · Antioxidants · doi:10.3390/antiox13020232 · Cited by 18 · see citing works

Oxidative stress and programmed cell death in diabetic wounds: A comprehensive review

Hong, L., Li, M., & Fan, Y. (2025) · Science Progress · doi:10.1177/00368504251370676 · Cited by 21 · see citing works

The redox signal: A physiological perspective

Margaritelis, N. V., Chatzinikolaou, P. N., Chatzinikolaou, A., Paschalis, V., Theodorou, A. A., Vrabas, I. S., Kyparos, A., & Nikolaidis, M. G. (2021) · IUBMB Life · doi:10.1002/iub.2550 · Cited by 17 · see citing works

Ten “Cheat Codes” for Measuring Oxidative Stress in Humans

Cobley, J. N., Margaritelis, N. V., Chatzinikolaou, P. N., Nikolaidis, M. G., & Davison, G. W. (2024) · Antioxidants · doi:10.3390/antiox13070877 · Cited by 17 · see citing works

Electrophilic Signaling: The Role of Reactive Carbonyl Compounds

Kosmachevskaya, O. V., Шумаев, К. Б., & Topunov, A. F. (2019) · Biochemistry (Moscow) · doi:10.1134/s0006297919140128 · Cited by 17 · see citing works

Half sandwich-type osmium, ruthenium, iridium and rhodium complexes with bidentate glycosyl heterocyclic ligands induce cytostasis in platinum-resistant ovarian cancer cells and bacteriostasis in Gram-positive multiresistant bacteria

Kacsir, I., Sipos, A., Kiss, T., Major, E., Bajusz, N., Tóth, E., Buglyó, P., Somsák, L., Kardos, G., Bai, P., et al. (2023) · Frontiers in Chemistry · doi:10.3389/fchem.2023.1086267 · Cited by 16 · see citing works

Aberrant reactive aldehyde detoxification by aldehyde dehydrogenase-2 influences endometriosis development and pain-associated behaviors

McAllister, S. L., Sinharoy, P., Vasu, M., & Gross, E. R. (2020) · Pain · doi:10.1097/j.pain.0000000000001949 · Cited by 16 · see citing works

Genie in a bottle: controlled release helps tame natural polypharmacology?

Long, M. J. C., Liu, X., & Aye, Y. (2019) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2019.02.014 · Cited by 15 · see citing works

Egg white consumption increases GSH and lowers oxidative damage in 110-week-old geriatric mice hearts

Ye, J., Botta, A. M., Simtchouk, S., Winkler, J., Renaud, L., Dadlani, H., Rasmussen, B., Elango, R., & Ghosh, S. (2019) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2019.108252 · Cited by 15 · see citing works

Activation of cellular signalling pathways and apoptosis by the aldehyde acrolein – A major environmental hazard

Averill‐Bates, D. A., & Tanel, A. (2023) · Redox Biochemistry and Chemistry · doi:10.1016/j.rbc.2023.100019 · Cited by 14 · see citing works

Nuclear Sphingosine-1-phosphate Lyase Generated ∆2-hexadecenal is A Regulator of HDAC Activity and Chromatin Remodeling in Lung Epithelial Cells

Ebenezer, D. L., Ramchandran, R., Fu, P., Mangio, L. A., Suryadevara, V., Ha, A. W., Berdyshev, E. V., Veldhoven, P. P. V., Kron, S. J., Schumacher, F., et al. (2021) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-021-01005-9 · Cited by 14 · see citing works

Suppression of hERG K+ current and cardiac action potential prolongation by 4-hydroxynonenal via dual mechanisms

Choi, S. W., Choi, S. W., Jeon, Y. K., Moon, S., Zhang, Y. H., & Kim, S. J. (2018) · Redox Biology · doi:10.1016/j.redox.2018.08.018 · Cited by 13 · see citing works

From aldehyde metabolism to delay aging: targeting ALDH2 as a novel strategy

Yang, P., Su, W., Wang, L., Xu, F., Kong, Y., & Long, J. (2025) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2025.05.389 · Cited by 12 · see citing works

l ‐Arginine prevents 4‐hydroxy‐2‐nonenal accumulation and depresses inflammation via inhibiting NF‐κB activation

Liang, M., Wang, Z., Li, H., Liu, B., & Yang, L. (2022) · Journal of Biochemical and Molecular Toxicology · doi:10.1002/jbt.23087 · Cited by 12 · see citing works

Multi-omics reveal disturbance of glucose homeostasis in pregnant rats exposed to short-chain perfluorobutanesulfonic acid

Yu, G., Luo, T., Liu, Y., Huo, X., Mo, C., Huang, B., Li, Y., Feng, L., Sun, Y., Zhang, J., et al. (2024) · Ecotoxicology and Environmental Safety · doi:10.1016/j.ecoenv.2024.116402 · Cited by 12 · see citing works

Chronic Oral D-Galactose Induces Oxidative Stress but Not Overt Organ Dysfunction in Male Wistar Rats

Martinović, J., Stojanović, I. G., Nešić, S., Todorović, A., Bobić, K., Stankovic, S. D., & Drakulić, D. (2025) · Current Issues in Molecular Biology · doi:10.3390/cimb47030161 · Cited by 10 · see citing works

Oxidative stress is inhibited by plant-based supplements: A quantitative lipidomic analysis of antioxidant activity and lipid compositional change

Bahja, J., Stewart, N. A., & Dymond, M. K. (2022) · Advances in Redox Research · doi:10.1016/j.arres.2022.100054 · Cited by 10 · see citing works

Editorial Introduction to the Special Issue on 4-Hydroxynonenal and Related Lipid Oxidation Products

Poli, G., & Žarković, N. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.05.016 · Cited by 10 · see citing works

Potential Role of Oxidative Stress in the Pathophysiology of Neurodegenerative Disorders

Singh, S. K., Ahuja, A., & Pathak, S. (2024) · Combinatorial Chemistry & High Throughput Screening · doi:10.2174/0113862073280680240101065732 · Cited by 10 · see citing works

Glucose-dependent insulinotropic polypeptide (GIP) alleviates ferroptosis in aging-induced brain damage through the Epac/Rap1 signaling pathway

Ko, J., Jang, S., Jang, S., Park, S., Yi, J. K., Choi, D. K., Kim, S., Kim, M. O., Lim, S., & Ryoo, Z. Y. (2024) · BMB Reports · doi:10.5483/bmbrep.2024-0067 · Cited by 9 · see citing works

Inflammation subsequent to mild iron excess differentially alters regional brain iron metabolism, oxidation and neuroinflammation status in mice

Ashraf, A., Aljuhani, M., Hubens, C. J., Jeandriens, J., Parkes, H. G., Geraki, K., Mahmood, A., Herlihy, A. H., & So, P. (2024) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2024.1393351 · Cited by 8 · see citing works

L-Methionine inhibits 4-hydroxy-2-nonenal accumulation and suppresses inflammation in growing rats

Wang, Z., Liang, M., Li, H., Liu, B., & Yang, L. (2022) · Nutrition Research and Practice · doi:10.4162/nrp.2022.16.6.729 · Cited by 8 · see citing works

Discovery adductomics provides a comprehensive portrait of tissue-, age- and sex-specific DNA modifications in rodents and humans

Guilbaud, A., Ghanegolmohammadi, F., Wang, Y., Leng, J., Kreymerman, A., Varela, J. G., Garbern, J. C., Elwell, H., Cao, F., Ricci-Blair, E. M., et al. (2023) · Nucleic Acids Research · doi:10.1093/nar/gkad822 · Cited by 8 · see citing works

Cannabidiol improves learning and memory deficits and alleviates anxiety in 12-month-old SAMP8 mice

Goodland, M. N., Banerjee, S., Niehoff, M. L., Young, B. J., Macarthur, H., Butler, A. A., Morley, J. E., & Farr, S. A. (2025) · PLoS ONE · doi:10.1371/journal.pone.0296586 · Cited by 7 · see citing works

Unlocking the Power of Antioxidant Nanoparticles: Insights into Classification, Formulation, Characterization, and Biomedical Applications

Khan, I., Hameed, H., Younas, K., Zaman, M., Faheem, S., Majeed, I., & Alvi, M. N. (2024) · BioNanoScience · doi:10.1007/s12668-024-01761-x · Cited by 6 · see citing works

Reduced Function of the Glutathione S-Transferase S1 Suppresses Behavioral Hyperexcitability in Drosophila Expressing Mutant Voltage-Gated Sodium Channels

Chen, H.-L., Kasuya, J., Lansdon, P., Kaas, G. A., Tang, H., Sodders, M., & Kitamoto, T. (2020) · G3 Genes Genomes Genetics · doi:10.1534/g3.119.401025 · Cited by 6 · see citing works

Physiological and pharmacological characterization of a molluscan neuronal efflux transporter; evidence for age-related transporter impairment

Hermann, P. M., Perry, A. C., Hamad, I., & Wildering, W. C. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.213785 · Cited by 5 · see citing works

Detection of HNE Modification of Proteins in Aging Mouse Tissues: A Western Blot-Based Approach

Zhang, H., Lyn, N., Haghani, A., & Forman, H. J. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0592-9_21 · Cited by 5 · see citing works

Protection against APOE4-associated phenotypes with the longevity-promoting intervention 17α-estradiol in middle-aged male mice

McGill, C. J., Christensen, A., Qian, W., Thorwald, M. A., Godoy-Lugo, J. A., Namvari, S., White, O. S., Finch, C. E., Benayoun, B. A., & Pike, C. J. (2025) · Communications Medicine · doi:10.1038/s43856-025-00942-3 · Cited by 4 · see citing works

Aldehyde Dehydrogenase 2 Preserves Mitochondrial Function in the Ischemic Heart: A Redox-dependent Mechanism for AMPK Activation by Thioredoxin-1

Zhu, Y., He, Y.-J., Yu, Y., Xu, D., Yuan, S., & Yan, H. (2023) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000001499 · Cited by 4 · see citing works

Frog-derived peptides and neuroprotection

Moreira, D. C., Batagin‐Neto, A., & Leite, J. R. S. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-23763-8.00018-x · Cited by 4 · see citing works

Increased oxidative stress in elderly leprosy patients is related to age but not to bacillary load

da Silva, P. H. L., de Castro, K. K. G., Mendes, M. A., Leal-Calvo, T., Leal, J. M. P., Hacker, M. A., Nery, J. A. D. C., Sarno, E. N., Lourenço, R. A., Moraes, M. O., et al. (2021) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0009214 · Cited by 4 · see citing works

Design and Synthesis of Multipotent Antioxidants for Functionalization of Iron Oxide Nanoparticles

Shah, S. T., Chowdhury, Z. Z., Johan, M. R., Badruddin, I. A., Alrobei, H., & Kamangar, S. (2022) · Coatings · doi:10.3390/coatings12040517 · Cited by 4 · see citing works

Oxidative damage in metal fragment-embedded Sprague-Dawley rat gastrocnemius muscle

Kalinich, J. F., Vergara, V. B., & Hoffman, J. F. (2022) · Current Research in Toxicology · doi:10.1016/j.crtox.2022.100083 · Cited by 4 · see citing works

A proteomic approach to investigate the role of the MECP2 gene mutation in Rett syndrome redox regulatory pathways

Pasqui, A., Cicaloni, V., Tinti, L., Guiotto, A., Tinti, C., Mori, A., Bruttini, M., Hayek, J., Pecorelli, A., Salvini, L., et al. (2023) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2023.109860 · Cited by 4 · see citing works

Ursodeoxycholic acid prompts glycolytic dominance, reductive stress and epithelial-to-mesenchymal transition in ovarian cancer cells through NRF2 activation

Sipos, A., Kerekes, É., Szeőcs, D., Szarvas, F., Schwarcz, S., Tóth, E., Ujlaki, G., Mikó, E., & Bai, P. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02398-9 · Cited by 3 · see citing works

Oxidative Stress and the KEAP1/NRF2 Axis in Saphenous Vein: Implications for Graft Patency

Layton, G. R., Marston, E., Musa, H. L., Ladak, S. S., Copperwheat, A., Oluwanifemi, A., Antoun, I., & Zakkar, M. (2026) · Cells · doi:10.3390/cells15060563 · Cited by 2 · see citing works

Modeling aging in a culture dish: towards the development of more sophisticated in vitro models of human skin aging

Briganti, S., Camera, E., Ciriza, J., Fernández-Carro, E., Krivokuća, M. J., Lamartine, J., Letsiou, S., Nacka-Aleksić, M., Niessen, C. M., Oliva, N., et al. (2026) · Ageing Research Reviews · doi:10.1016/j.arr.2026.103109 · Cited by 3 · see citing works

Effect of Capsicum annuum leaf extract addition timing on yogurt bioactivity, digestibility, and cellular antioxidant defence

Ibrahim, A. N., Xu, N., Shen, S., Yang, Z., Zeng, L., & Zhang, Y. S. (2026) · Food & Function · doi:10.1039/d6fo00042h · Cited by 2 · see citing works

Nanomedicine-enabled ferroptosis intervention:from antitumor effects to immune remodeling in lung diseases

Zhang, Y., Huang, W., Zhu, K., Si, Q., Wang, T., & Qin, Y. (2026) · Biomaterials · doi:10.1016/j.biomaterials.2026.124301 · Cited by 2 · see citing works

Asian Flush Gene Variant Enhances Cellular Immunogenicity of COVID-19 Vaccine: Prospective Observation in the Japanese General Population

Bogahawaththa, S., Hara, M., Furukawa, T., Iwasaka, C., Sawada, T., Yamada, G., Tokiya, M., Kitagawa, K., Miyake, Y., Kido, M. A., et al. (2024) · Vaccines · doi:10.3390/vaccines12091015 · Cited by 2 · see citing works

Protein Expression in the Gastrocnemius Muscle of a Rodent Shrapnel-Injury Model

Hoffman, J. F., Vergara, V. B., & Kalinich, J. F. (2021) · International Journal of Toxicology · doi:10.1177/10915818211062878 · Cited by 2 · see citing works

Protection against APOE4 -associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male micePreprint

McGill, C. J., Christensen, A., Qian, W., Thorwald, M. A., Lugo, J. G., Namvari, S., White, O. S., Finch, C. E., Benayoun, B. A., & Pike, C. J. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.03.12.584678 · Cited by 2 · see citing works

Aberrant mitochondria in endometriosis: From pathogenic mechanisms to therapeutic opportunities

Rong, Y., Zhu, J., Wang, C. C., Zhang, J., & Chen, Y. (2026) · iScience · doi:10.1016/j.isci.2026.115916 · Cited by 1 · see citing works

Mitochondrial vulnerability to aldehydic load and the role mitochondrial aldehyde dehydrogenases

Seike, T., & Mochly‐Rosen, D. (2026) · Pharmacological Research · doi:10.1016/j.phrs.2026.108285 · Cited by 1 · see citing works

Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability

Wang, Z., Liang, M., Li, H., Liu, B., & Yang, L. (2022) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2021-0575 · Cited by 1 · see citing works

4-hydroxy-2-nonenal as a marker of the oxidative stress in brains of dogs with canine distemper

Viscone, É. A., Oliveira, L. A., Pereira, A. A. B. G., de Castro, M. B., Brandão, P. E., Taniwaki, S. A., da Hora, A. S., & Bandarra, M. D. B. (2022) · Brazilian Journal of Veterinary Research and Animal Science · doi:10.11606/issn.1678-4456.bjvras.2022.188941 · Cited by 1 · see citing works

Effects of Gallic Acid on Antioxidant Defense System in Mice with Benzene-Induced MyelotoxicityPreprint

Olatoye, T. I., & Adebayo, J. O. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.12.598751 · Cited by 1 · see citing works

Avaliação imunohistoquímica do estresse oxidativo no sistema nervoso central de cães positivos para cinomose

Viscone, É. A. (2020) · doi:10.14393/ufu.di.2020.9

Oxidized (Phospho)lipids

Ni, Z., & Fedorova, M. (2017) · Springer eBooks · doi:10.1007/978-94-007-7864-1_183-1

Antioxidants and cognitive decline in elderly

Lobine, D., & Mahomoodally, M. F. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-819096-8.00054-9

GDAP1 binds 4-hydroxynonenal, the toxic end-product of lipid peroxidation, using its GST-like binding pocketPreprint

Googins, M. R., Brown, M. R., Woghiren‐Afegbua, A. O., Kiselyov, K. I., & VanDemark, A. P. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.10.28.514248

Tissue- and sex-specific DNA damage tracks aging in rodents and humansPreprint

Guilbaud, A., Ghanegolmohammadi, F., Wang, Y., Leng, J., Kreymerman, A., Varela, J. G., Garbern, J. C., Elwell, H., Cao, F., Ricci-Blair, E. M., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.11.28.518087

HNE-mediated cell signaling

Forman, H. J. (2018) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2018.05.011

4-Hydroxynonenal in the Pathogenesis and Progression of Human Diseases

Shoeb, M., Ansari, N., Srivastava, S., & Ramana, K. (2013) · Current Medicinal Chemistry · doi:10.2174/09298673113209990181 · Cited by 230 · see citing works

Oxidative Stress and 4-hydroxy-2-nonenal (4-HNE): Implications in the Pathogenesis and Treatment of Aging-related Diseases

Li, Y., Zhao, T., Li, J., Xia, M., Li, Y., Wang, X., Liu, C., Zheng, T., Chen, R., Kan, D., et al. (2022) · Journal of Immunology Research · doi:10.1155/2022/2233906 · Cited by 185 · see citing works

Age-related alteration in HNE elimination enzymes

Zhang, H., Morgan, T. E., & Forman, H. J. (2021) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2020.108749 · Cited by 20 · see citing works

On the role of 4-hydroxynonenal in health and disease

Csala, M., Kardon, T., Legeza, B., Lizák, B., Mandl, J., Margittai, É., Puskás, F., Száraz, P., Szelényi, P., & Bánhegyi, G. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.01.015 · Cited by 244 · see citing works