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Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis

Harris, P. A., Bandyopadhyay, D., Berger, S. B., Campobasso, N., Capriotti, C. A., Cox, J. A., Dare, L. C., Finger, J. N., Hoffman, S. J., Kahler, K. M., et al. (2013) · ACS Medicinal Chemistry Letters · doi:10.1021/ml400382p · Cited by 142 · see citing works

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Lee, E., Seo, J.-H., Jeong, M.-H., Lee, S.-S., & Song, J.-W. (2012) · BMB Reports · doi:10.5483/bmbrep.2012.45.9.186 · Cited by 137 · see citing works

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Cell Death-Associated Molecular-Pattern Molecules: Inflammatory Signaling and Control

Sangiuliano, B. A., Pérez-Sosa, M., Moreira, D., & Belizário, J. E. (2014) · Mediators of Inflammation · doi:10.1155/2014/821043 · Cited by 136 · see citing works

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Weinlich, R., & Green, D. R. (2014) · Molecular Cell · doi:10.1016/j.molcel.2014.11.001 · Cited by 127 · see citing works

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Huang, D., Zheng, X., Wang, Z.-A., Chen, X., He, W., Zhang, Y., Xu, J.-G., Zhao, H., Shi, W., Wang, X., et al. (2016) · Molecular and Cellular Biology · doi:10.1128/mcb.00497-16 · Cited by 132 · see citing works

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Lee, E., Kim, J.-H., Ahn, Y.-H., Seo, J., Ko, A., Jeong, M., Kim, S.-J., Ro, J. Y., Park, K.-M., Lee, H., et al. (2012) · Nature Communications · doi:10.1038/ncomms1981 · Cited by 130 · see citing works

Positive and negative phosphorylation regulates RIP1- and RIP3-induced programmed necrosis

McQuade, T. J., Cho, Y., & Chan, F. K.-M. (2013) · Biochemical Journal · doi:10.1042/bj20130860 · Cited by 129 · see citing works

RIP3 Inhibits Inflammatory Hepatocarcinogenesis but Promotes Cholestasis by Controlling Caspase-8- and JNK-Dependent Compensatory Cell Proliferation

Vucur, M., Reisinger, F., Gautheron, J., Janssen, J., Roderburg, C., Cardenas, D. V., Kreggenwinkel, K., Koppe, C., Hammerich, L., Hakem, R., et al. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.07.035 · Cited by 127 · see citing works

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Witt, A., & Vucic, D. (2017) · Cell Death and Differentiation · doi:10.1038/cdd.2017.33 · Cited by 126 · see citing works

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Feltham, R., Vince, J. E., & Lawlor, K. E. (2017) · Clinical & Translational Immunology · doi:10.1038/cti.2016.83 · Cited by 123 · see citing works

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Choi, S.-W., Park, H., Kim, S., Chung, J. M., Noh, H.-J., Kim, S. K., Song, H. K., Lee, C., Morgan, M. J., Kang, H. C., et al. (2018) · Molecular Cell · doi:10.1016/j.molcel.2018.05.016 · Cited by 116 · see citing works

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Li, L., Chen, Y., Doan, J., Murray, J. D., Molkentin, J. D., & Liu, Q. (2014) · Circulation · doi:10.1161/circulationaha.114.011195 · Cited by 112 · see citing works

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Tonnus, W., & Linkermann, A. (2017) · Immunological Reviews · doi:10.1111/imr.12551 · Cited by 109 · see citing works

Multitasking Kinase RIPK1 Regulates Cell Death and InflammationPreprint

Newton, K. (2019) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a036368 · Cited by 106 · see citing works

Non‐apoptotic functions of apoptosis‐regulatory proteins

Galluzzi, L., Kepp, O., Trojel‐Hansen, C., & Kroemer, G. (2012) · The EMBO Reports · doi:10.1038/embor.2012.19 · Cited by 109 · see citing works

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Mocarski, E. S., Guo, H., & Kaiser, W. J. (2015) · Virology · doi:10.1016/j.virol.2015.03.016 · Cited by 104 · see citing works

Current translational potential and underlying molecular mechanisms of necroptosis

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Williams, J., Manley, S., & Ding, W. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i36.12908 · Cited by 102 · see citing works

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1

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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

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