The Aging Cardiovascular System

The Hallmarks of Aging

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Prediction of coronary heart disease using risk factor categories

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Age-related clonal hematopoiesis associated with adverse outcomes

Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., et al. (2014) · New England Journal of Medicine · doi:10.1056/nejmoa1408617 · Cited by 4,841 · see citing works

Trends in Prevalence and Outcome of Heart Failure with Preserved Ejection Fraction

Owan, T., Hodge, D. O., Herges, R. M., Jacobsen, S. J., Roger, V. L., & Redfield, M. M. (2006) · New England Journal of Medicine · doi:10.1056/nejmoa052256 · Cited by 4,191 · see citing works

Ageing populations: the challenges ahead

Christensen, K., Doblhammer, G., Rau, R., & Vaupel, J. W. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61460-4 · Cited by 3,764 · see citing works

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y., et al. (2004) · Science · doi:10.1126/science.1094637 · Cited by 3,239 · see citing works

Forecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart Association

Heidenreich, P. A., Trogdon, J. G., Khavjou, O. A., Butler, J., Dracup, K., Ezekowitz, M. D., Finkelstein, E. A., Hong, Y., Johnston, S. C., Khera, A., et al. (2011) · Circulation · doi:10.1161/cir.0b013e31820a55f5 · Cited by 3,208 · see citing works

Treatment of hypertension in patients 80 years of age or older

Beckett, N. S., Peters, R., Fletcher, A. E., Staessen, J. A., Liu, L., Dumitrascu, D., Stoyanovsky, V., Antikainen, R. L., Nikitin, Y., Anderson, C., et al. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0801369 · Cited by 3,092 · see citing works

Sarcopenia: origins and clinical relevance

Rosenberg, I. H. (1997) · The Journal of Nutrition · doi:10.1093/jn/127.5.990s · Cited by 2,399 · see citing works

Arterial and Cardiac Aging: Major Shareholders in Cardiovascular Disease Enterprises: Part I: Aging Arteries: A “Set Up” for Vascular Disease

Lakatta, E. G., & Levy, D. (2003) · Circulation · doi:10.1161/01.cir.0000048892.83521.58 · Cited by 2,244 · see citing works

Suppression of Aging in Mice by the Hormone Klotho

Kurosu, H., Yamamoto, M., Clark, J. D., Pastor, J. V., Nandi, A., Gurnani, P., McGuinness, O. P., Chikuda, H., Yamaguchi, M., Kawaguchi, H., et al. (2005) · Science · doi:10.1126/science.1112766 · Cited by 1,935 · see citing works

Mechanisms, Pathophysiology, and Therapy of Arterial Stiffness

Zieman, S. J., Melenovsky, V., & Kass, D. A. (2005) · Arteriosclerosis, Thrombosis, and Vascular Biology · doi:10.1161/01.atv.0000160548.78317.29 · Cited by 1,854 · see citing works

The DNA damage response and cancer therapy

Lord, C. J., & Ashworth, A. (2012) · Nature · doi:10.1038/nature10760 · Cited by 1,843 · see citing works

Is Pulse Pressure Useful in Predicting Risk for Coronary Heart Disease?

Franklin, S. S., Khan, S. A., Wong, N. D., Larson, M. G., & Levy, D. A. (1999) · Circulation · doi:10.1161/01.cir.100.4.354 · Cited by 1,756 · see citing works

The p66shc adaptor protein controls oxidative stress response and life span in mammals

Migliaccio, E., Giorgio, M., Mele, S., Pelicci, G., Reboldi, P., Pandolfi, P. P., Lanfrancone, L., & Pelicci, P. G. (1999) · Nature · doi:10.1038/46311 · Cited by 1,712 · see citing works

Lifetime Risk for Developing Congestive Heart Failure

Lloyd‐Jones, D. M., Larson, M. G., Leip, E. P., Beiser, A., D’Agostino, R. B., Kannel, W. B., Murabito, J. M., Vasan, R. S., Benjamin, E. J., & Levy, D. A. (2002) · Circulation · doi:10.1161/01.cir.0000039105.49749.6f · Cited by 1,615 · see citing works

The intersection between aging and cardiovascular disease

North, B. J., & Sinclair, D. A. (2012) · Circulation Research · doi:10.1161/circresaha.111.246876 · Cited by 1,585 · see citing works

Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial

Forette, F., Seux, M.-L., Staessen, J. A., Thijs, L., Birkenhäger, W. H., Babarskiene, M.-R., Babeanu, S., Bossini, A., Gil-Extremera, B., Girerd, X., et al. (1998) · The Lancet · doi:10.1016/s0140-6736(98)03086-4 · Cited by 1,441 · see citing works

Aging is associated with endothelial dysfunction in healthy men years before the age-related decline in women

Celermajer, D. S., Sørensen, K. E., Spiegelhalter, D. J., Georgakopoulos, D., Robinson, J. T. C., & Deanfield, J. E. (1994) · Journal of the American College of Cardiology · doi:10.1016/0735-1097(94)90305-0 · Cited by 1,334 · see citing works

Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial

Williamson, J. D., Supiano, M. A., Applegate, W. B., Berlowitz, D. R., Campbell, R. C., Chertow, G. M., Fine, L. J., Haley, W. E., Hawfield, A. T., Ix, J. H., et al. (2016) · JAMA · doi:10.1001/jama.2016.7050 · Cited by 1,261 · see citing works

Wild-type transthyretin amyloidosis as a cause of heart failure with preserved ejection fraction

González-López, E., Gallego‐Delgado, M., Guzzo-Merello, G., Moral, F. J. D. H.-D., Marcos, M. C., Robles, C., Bornstein, B., Salas, C., Lara‐Pezzi, E., Alonso‐Pulpón, L., et al. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv338 · Cited by 1,176 · see citing works

Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease.

Vita, J. A., Treasure, C. B., Nabel, E. G., McLenachan, J. M., Fish, R. D., Yeung, A. C., Vekshtein, V. I., Selwyn, A. P., & Ganz, P. (1990) · Circulation · doi:10.1161/01.cir.81.2.491 · Cited by 1,172 · see citing works

Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials

Staessen, J. A., Gąsowski, J., Wang, J. G., Thijs, L., Hond, E. D., Boissel, J., Coope, J., Ekbom, T., Gueyffier, F., Liu, L., et al. (2000) · The Lancet · doi:10.1016/s0140-6736(99)07330-4 · Cited by 1,159 · see citing works

Genetic Associations with Valvular Calcification and Aortic Stenosis

Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1109034 · Cited by 1,008 · see citing works

Untitled work

Wang (2012) · doi:10.1161/circresaha.111.261388 · Cited by 957 · see citing works

SIRT1 Promotes Endothelium-Dependent Vascular Relaxation by Activating Endothelial Nitric Oxide Synthase

Mattagajasingh, I., Kim, C.-S., Naqvi, A., Yamamori, T., Hoffman, T. A., Jung, S.-B., DeRicco, J., Kasuno, K., & Irani, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0704329104 · Cited by 881 · see citing works

Recent Trends in Disability and Functioning Among Older Adults in the United States

Freedman, V. A., Martin, L. G., & Schoeni, R. F. (2002) · JAMA · doi:10.1001/jama.288.24.3137 · Cited by 867 · see citing works

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

Haycock, P. C., Heydon, E. E., Kaptoge, S., Butterworth, A. S., Thompson, A., & Willeit, P. (2014) · BMJ · doi:10.1136/bmj.g4227 · Cited by 856 · see citing works

Diagnosis and Management of the Cardiac Amyloidoses

Falk, R. H. (2005) · Circulation · doi:10.1161/circulationaha.104.489187 · Cited by 795 · see citing works

Telomere Diseases

Calado, R. T., & Young, N. S. (2009) · New England Journal of Medicine · doi:10.1056/nejmra0903373 · Cited by 783 · see citing works

Dogma Disputed: Can Aggressively Lowering Blood Pressure in Hypertensive Patients with Coronary Artery Disease Be Dangerous?

Messerli, F. H., Mancia, G., Conti, C. R., Hewkin, A. C., Kupfer, S., Champion, A., Kolloch, R. E., Bénétos, A., & Pepine, C. J. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-12-200606200-00005 · Cited by 777 · see citing works

Telomere length, risk of coronary heart disease, and statin treatment in the West of Scotland Primary Prevention Study: a nested case-control study

Brouilette, S., Moore, J. S., McMahon, A. D., Thompson, J. R., Ford, I., Shepherd, J., Packard, C. J., & Samani, N. J. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60071-3 · Cited by 744 · see citing works

Predominance of Isolated Systolic Hypertension Among Middle-Aged and Elderly US Hypertensives

Franklin, S. S., Jacobs, M. J., Wong, N. D., L'Italien, G. J., & Lapuerta, P. (2001) · Hypertension · doi:10.1161/01.hyp.37.3.869 · Cited by 705 · see citing works

Enhanced Peroxynitrite Formation Is Associated with Vascular Aging

van der Loo, B., Labugger, R., Skepper, J. N., Bachschmid, M. M., Kilo, J., Powell, J. M., Palacios‐Callender, M., Erusalimsky, J. D., Quaschning, T., Maliñski, T., et al. (2000) · The Journal of Experimental Medicine · doi:10.1084/jem.192.12.1731 · Cited by 674 · see citing works

Age-Related Reduction of NO Availability and Oxidative Stress in Humans

Taddei, S., Virdis, A., Ghiadoni, L., Salvetti, G., Bernini, G., Magagna, A., & Salvetti, A. (2001) · Hypertension · doi:10.1161/01.hyp.38.2.274 · Cited by 664 · see citing works

Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes

Aronson, D. (2003) · Journal of Hypertension · doi:10.1097/00004872-200301000-00002 · Cited by 652 · see citing works

Critical Reevaluation of Endothelial Progenitor Cell Phenotypes for Therapeutic and Diagnostic Use

Fadini, G. P., Losordo, D. W., & Dimmeler, S. (2012) · Circulation Research · doi:10.1161/circresaha.111.243386 · Cited by 633 · see citing works

Aortic-Valve Stenosis — From Patients at Risk to Severe Valve Obstruction

Otto, C. M., & Prendergast, B. (2014) · New England Journal of Medicine · doi:10.1056/nejmra1313875 · Cited by 631 · see citing works

Role of Frailty in Patients With Cardiovascular Disease

Afilalo, J., Karunananthan, S., Eisenberg, M. J., Alexander, K. P., & Bergman, H. (2009) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2009.01.375 · Cited by 616 · see citing works

Cytokines and growth factors positively and negatively regulate interstitial collagen gene expression in human vascular smooth muscle cells.

Amento, E. P., Ehsani, N., Palmer, H., & Libby, P. (1991) · Arteriosclerosis and Thrombosis: A Journal of Vascular Biology · doi:10.1161/01.atv.11.5.1223 · Cited by 609 · see citing works

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

Bollati, V., Schwartz, J. D., Wright, R. O., Litonjua, A. A., Tarantini, L., Suh, H. H., Sparrow, D., Vokonas, P., & Baccarelli, A. (2008) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2008.12.003 · Cited by 594 · see citing works

JunD Reduces Tumor Angiogenesis by Protecting Cells from Oxidative Stress

Gerald, D., Berra, E., Frapart, Y. M., Chan, D. A., Giaccia, A. J., Mansuy, D., Pouysségur, J., Yaniv, M., & Mechta-Grigoriou, F. (2004) · Cell · doi:10.1016/j.cell.2004.08.025 · Cited by 588 · see citing works

Randomised trial of α-tocopherol and β-carotene supplements on incidence of major coronary events in men with previous myocardial infarction

Rapola, J., Virtamo, J. R. K., Ripatti, S., Huttunen, J. K., Albanes, D., Taylor, P. R., & Heinonen, O. P. (1997) · The Lancet · doi:10.1016/s0140-6736(97)01234-8 · Cited by 569 · see citing works

Direct Evidence of Endothelial Oxidative Stress With Aging in Humans

Donato, A. J., Eskurza, I., Silver, A., Levy, A., Pierce, G. L., Gates, P. E., & Seals, D. R. (2007) · Circulation Research · doi:10.1161/01.res.0000269183.13937.e8 · Cited by 558 · see citing works

Heart Failure with Preserved Ejection Fraction

Redfield, M. M. (2016) · New England Journal of Medicine · doi:10.1056/nejmcp1511175 · Cited by 513 · see citing works

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

Menghini, R., Casagrande, V., Cardellini, M., Martelli, E., Terrinoni, A., Amati, F., Vasa‐Nicotera, M., Ippoliti, A., Novelli, G., Melino, G., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.864629 · Cited by 479 · see citing works

Cardiovascular event rates and mortality according to achieved systolic and diastolic blood pressure in patients with stable coronary artery disease: an international cohort study

Vidal-Petiot, E., Ford, I., Greenlaw, N., Ferrari, R., Fox, K. M., Tardif, J.-C., Tendera, M., Tavazzi, L., Bhatt, D. L., & Steg, P. G. (2016) · The Lancet · doi:10.1016/s0140-6736(16)31326-5 · Cited by 470 · see citing works

Dual Angiotensin Receptor and Neprilysin Inhibition as an Alternative to Angiotensin-Converting Enzyme Inhibition in Patients with Chronic Systolic Heart Failure: Rationale for and Design of the Prospective Comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure Trial (PARADIGM-HF)

McMurray, J. J. V., Packer, M., Desai, A. S., Gong, J., Lefkowitz, M. P., Rizkala, A. R., Rouleau, J. L., Shi, V. C., Solomon, S. D., Swedberg, K. B., et al. (2013) · European Journal of Heart Failure · doi:10.1093/eurjhf/hft052 · Cited by 458 · see citing works

Protective effects of sirtuins in cardiovascular diseases: from bench to bedside

Winnik, S. H., Auwerx, J. H., Sinclair, D. A., & Matter, C. M. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv290 · Cited by 443 · see citing works

Sirt1 modulates premature senescence-like phenotype in human endothelial cells

Ota, H., Akishita, M., Eto, M., Iijima, K., Kaneki, M., & Ouchi, Y. (2007) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2007.08.008 · Cited by 422 · see citing works

Lysosomal Cysteine Proteases in Atherosclerosis

Liu, J., Sukhova, G. K., Sun, J., Xu, W., Libby, P., & Shi, G. (2004) · Arteriosclerosis Thrombosis and Vascular Biology · doi:10.1161/01.atv.0000134530.27208.41 · Cited by 397 · see citing works

Endothelium-specific overexpression of class III deacetylase SIRT1 decreases atherosclerosis in apolipoprotein E-deficient mice

Zhang, Q., Wang, Z., Chen, H., Zhou, S., Zheng, W., Liu, G., Wei, Y.-S., Cai, H. “., Liu, D., & Liang, C. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn224 · Cited by 388 · see citing works

Genome Instability and Aging

Vijg, J., & Suh, Y. (2013) · Annual Review of Physiology · doi:10.1146/annurev-physiol-030212-183715 · Cited by 386 · see citing works

Determinants of Muscle and Bone Aging

Curtis, E., Litwic, A., Cooper, C., & Dennison, E. (2015) · Journal of Cellular Physiology · doi:10.1002/jcp.25001 · Cited by 375 · see citing works

eNOS uncoupling and endothelial dysfunction in aged vessels

Yang, Y., Huang, A., Kaley, G., & Sun, D. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00230.2009 · Cited by 370 · see citing works

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

Dikalov, S. I., & Nazarewicz, R. R. (2013) · Antioxidants & Redox Signaling · doi:10.1089/ars.2012.4604 · Cited by 356 · see citing works

Diastolic Blood Pressure, Subclinical Myocardial Damage, and Cardiac Events

McEvoy, J. W., Chen, Y., Rawlings, A. M., Hoogeveen, R. C., Ballantyne, C. M., Blumenthal, R. S., Coresh, J., & Selvin, E. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.07.754 · Cited by 355 · see citing works

Increased mitochondrial H 2 O 2 production promotes endothelial NF-κB activation in aged rat arteries

Ungvari, Z. I., Orosz, Z. Z., Labinskyy, N., Rivera, A., Xiangmin, Z., Smith, K. E., & Csiszár, A. (2007) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.01346.2006 · Cited by 347 · see citing works

Stem cells and healthy aging

Goodell, M. A., & Rando, T. A. (2015) · Science · doi:10.1126/science.aab3388 · Cited by 347 · see citing works

MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1

Zhao, T., Li, J., & Chen, A. F. (2010) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00192.2010 · Cited by 328 · see citing works

Vascular endothelial dysfunction with aging: endothelin-1 and endothelial nitric oxide synthase

Donato, A. J., Gano, L. B., Eskurza, I., Silver, A., Gates, P. E., Jablonski, K., & Seals, D. R. (2009) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00689.2008 · Cited by 318 · see citing works

Meta-Analysis of Cell-based CaRdiac stUdiEs (ACCRUE) in Patients With Acute Myocardial Infarction Based on Individual Patient Data

Gyöngyösi, M., Wojakowski, W., Lemarchand, P., Lunde, K., Tendera, M., Bartunek, J., Marbán, E., Aßmus, B., Henry, T. D., Traverse, J. H., et al. (2015) · Circulation Research · doi:10.1161/circresaha.116.304346 · Cited by 313 · see citing works

Constitutive Human Telomerase Reverse Transcriptase Expression Enhances Regenerative Properties of Endothelial Progenitor Cells

Murasawa, S., Llevadot, J., Silver, M., Isner, J. M., Losordo, D. W., & Asahara, T. (2002) · Circulation · doi:10.1161/01.cir.0000027584.85865.b4 · Cited by 303 · see citing works

Deletion of p66 ^shc Gene Protects Against Age-Related Endothelial Dysfunction

Francia, P., delli Gatti, C., Bachschmid, M., Martin-Padura, I., Savoia, C., Migliaccio, E., Pelicci, P. G., Schiavoni, M., Lüscher, T. F., Volpe, M., et al. (2004) · Circulation · doi:10.1161/01.cir.0000147731.24444.4d · Cited by 298 · see citing works

Effects of aging on angiogenesis

Lähteenvuo, J., & Rosenzweig, A. (2012) · Circulation Research · doi:10.1161/circresaha.111.246116 · Cited by 292 · see citing works

Different Mechanisms of Endothelial Dysfunction With Aging and Hypertension in Rat Aorta

Küng, C. F., & Lüscher, T. F. (1995) · Hypertension · doi:10.1161/01.hyp.25.2.194 · Cited by 281 · see citing works

Effects of Reduced Sodium Intake on Hypertension Control in Older Individuals

Appel, L. J., Espeland, M. A., Easter, L. H., Wilson, A. C., Folmar, S. J., & Lacy, C. R. (2001) · Archives of Internal Medicine · doi:10.1001/archinte.161.5.685 · Cited by 274 · see citing works

Repression of P66Shc Expression by SIRT1 Contributes to the Prevention of Hyperglycemia-Induced Endothelial Dysfunction

Zhou, S., Chen, H., Wan, Y.-Z., Zhang, Q.-J., Wei, Y.-S., Huang, S., Liu, J., Lu, Y., Zhang, Z., Yang, R., et al. (2011) · Circulation Research · doi:10.1161/circresaha.111.243592 · Cited by 273 · see citing works

AGE, HYPERTENSION AND ARTERIAL FUNCTION

McEniery, C. M., Wilkinson, I. B., & Avolio, A. P. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04657.x · Cited by 267 · see citing works

Epigenetics of Aging and Aging-related Disease

Brunet, A., & Berger, S. L. (2014) · The Journals of Gerontology Series A · doi:10.1093/gerona/glu042 · Cited by 263 · see citing works

Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery.

Tschudi, M. R., Barton, M., Bersinger, N. A., Moreau, P. R., Cosentino, F., Noll, G., Maliñski, T., & Lüscher, T. F. (1996) · Journal of Clinical Investigation · doi:10.1172/jci118872 · Cited by 260 · see citing works

Voluntary wheel running restores endothelial function in conduit arteries of old mice: direct evidence for reduced oxidative stress, increased superoxide dismutase activity and down‐regulation of NADPH oxidase

Durrant, J., Seals, D. R., Connell, M. L., Russell, M. J., Lawson, B. R., Folian, B. J., Donato, A. J., & Lesniewski, L. A. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2009.169771 · Cited by 244 · see citing works

Mechanisms Underlying Caloric Restriction and Lifespan Regulation

Ungvari, Z. I., Parrado‐Fernández, C., Csiszár, A., & de Cabo, R. (2008) · Circulation Research · doi:10.1161/circresaha.107.168369 · Cited by 239 · see citing works

Sodium Intake and All-Cause Mortality Over 20 Years in the Trials of Hypertension Prevention

Cook, N. R., Appel, L. J., & Whelton, P. K. (2016) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2016.07.745 · Cited by 228 · see citing works

Skeletal muscle capillary density and microvascular function are compromised with aging and type 2 diabetes

Groen, B. B. L., Hamer, H. M., Snijders, T., van Kranenburg, J. M. X., Frijns, D., Vink, H., & van Loon, L. J. C. (2014) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00919.2013 · Cited by 224 · see citing works

Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease

Camici, G. G., Savarese, G., Akhmedov, A., & Lüscher, T. F. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv587 · Cited by 223 · see citing works

Cellular Senescence, Vascular Disease, and Aging

Kovacic, J. C., Moreno, P., Nabel, E. G., Hachinski, V., & Fuster, V. (2011) · Circulation · doi:10.1161/circulationaha.110.009118 · Cited by 222 · see citing works

SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

Stein, S. M. A., Lohmann, C., Schäfer, N., Hofmann, J., Rohrer, L., Besler, C., Rothgiesser, K., Becher, B., Hottiger, M. O., Borén, J., et al. (2010) · European Heart Journal · doi:10.1093/eurheartj/ehq107 · Cited by 219 · see citing works

Mitochondrial Reactive Oxygen Species at the Heart of the Matter

Kornfeld, O. S., Hwang, S., Disatnik, M., Chen, C., Qvit, N., & Mochly‐Rosen, D. (2015) · Circulation Research · doi:10.1161/circresaha.116.305432 · Cited by 210 · see citing works

Osteoporosis and sarcopenia

Reginster, J., Beaudart, C., Buckinx, F., & Bruyère, O. (2015) · Current Opinion in Clinical Nutrition & Metabolic Care · doi:10.1097/mco.0000000000000230 · Cited by 207 · see citing works

Increased Expression of Matrix Metalloproteinase-2 in the Thickened Intima of Aged Rats

Li, Z., Froehlich, J. P., Galis, Z. S., & Lakatta, E. G. (1999) · Hypertension · doi:10.1161/01.hyp.33.1.116 · Cited by 203 · see citing works

Dementia and Disability Outcomes in Large Hypertension Trials: Lessons Learned from the Systolic Hypertension in the Elderly Program (SHEP) Trial

Di Bari, M., Pahor, M., Franse, L. V., Shorr, R. I., Wan, J. Y., Ferrucci, L., Somes, G. W., & Applegate, W. B. (2001) · American Journal of Epidemiology · doi:10.1093/aje/153.1.72 · Cited by 193 · see citing works

Nucleotide Excision DNA Repair Is Associated With Age-Related Vascular Dysfunction

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