Cited by 423Posttraumatic Stress Disorder ResearchStress Responses and CortisolChild Abuse and Trauma

The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.

Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis

Kitayama, Noriyuki, Vaccarino, Viola, Kutner, Michael, Weiss, Paul, Bremner, J. Douglas·2005·Journal of Affective Disorders

DOI 10.1016/j.jad.2005.05.014

Open this paper in CoChat — free account

Abstract

Background Studies in animals showed that the hippocampus, a brain area involved in learning and memory, is sensitive to stress. Although several MRI studies showed smaller hippocampal volume in adults with chronic PTSD, others did not show significant differences from controls. These studies are typified by small sample sizes which may limit the ability to show significant differences. We therefore performed a meta-analytic study of all of these studies to clarify the role of hippocampal structural changes in subjects with PTSD. Methods Nine studies with a total of 133 adult subjects with chronic PTSD, 148 healthy controls, and 53 traumatized controls were included in the meta-analysis. Results There was significantly smaller volume in both right and left hippocampi in adult subjects with chronic PTSD in comparison with both healthy controls and traumatized controls. Conclusion These findings are consistent with smaller hippocampal volume in adult subjects with chronic PTSD.

Integrity signals

Registry

Crossref · 10.1016/j.jad.2005.05.014

Cites

49 of 49 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Posttraumatic Stress Disorder in the National Comorbidity Survey
Kessler, R. C. (1995) · Archives of General Psychiatry · doi:10.1001/archpsyc.1995.03950240066012 · Cited by 10,379
Book Reviews: Statistical Methods for Meta-Analysis Larry V. Hedges and Ingram Olkin New York: Academic Press, 1985. xxii + 369 pp
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
Methods of Meta-Analysis: Correcting Error and Bias in Research Findings
Schmidt, F. L., & Hunter, J. E. (2015) · doi:10.4135/9781483398105 · Cited by 5,542
The Handbook of Research Synthesis.
Howel, D., Cooper, H., & Hedges, L. V. (1995) · Biometrics · doi:10.2307/2533295 · Cited by 3,657
Statistical Methods for Meta-Analysis
(1985) · Elsevier eBooks · doi:10.1016/c2009-0-03396-0 · Cited by 2,570
Methods of Meta-Analysis: Correcting Error and Bias in Research Findings.
Raudenbush, S. W., Hunter, J. E., & Schmidt, F. L. (1991) · Journal of the American Statistical Association · doi:10.2307/2289738 · Cited by 2,368
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
Nibuya, M., Morinobu, S., & Duman, R. (1995) · The Journal of Neuroscience · doi:10.1523/jneurosci.15-11-07539.1995 · Cited by 2,109
The Handbook of Research Synthesis.
Light, R. J., Cooper, H., & Hedges, L. V. (1994) · Journal of the American Statistical Association · doi:10.2307/2291021 · Cited by 1,880
Smaller hippocampal volume predicts pathologic vulnerability to psychological trauma
Gilbertson, M. W., Shenton, M. E., Ciszewski, A., Kasai, K., Lasko, N. B., Orr, S. P., & Pitman, R. K. (2002) · Nature Neuroscience · doi:10.1038/nn958 · Cited by 1,635
MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder
(1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.7.973 · Cited by 1,610
Self-citation

Flagged first, then by citations

Show all 49 references

Sorted by citations

The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.83 · Cited by 2,083
Whither opportunity?: rising inequality, schools, and children's life chances
(2012) · Choice Reviews Online · doi:10.5860/choice.49-5804 · Cited by 1,745
Biological studies of post-traumatic stress disorder
Pitman, R. K., Rasmusson, A. M., Koenen, K. C., Shin, L. M., Orr, S. P., Gilbertson, M. W., Milad, M. R., & Liberzon, I. (2012) · Nature Reviews Neuroscience · doi:10.1038/nrn3339 · Cited by 1,529
Borderline personality disorder
Leichsenring, F., Leibing, E., Kruse, J., New, A. S., & Leweke, F. (2011) · The Lancet · doi:10.1016/s0140-6736(10)61422-5 · Cited by 895
A meta-analysis of structural brain abnormalities in PTSD
KARL, A., SCHAEFER, M., MALTA, L., DORFEL, D., ROHLEDER, N., & WERNER, A. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2006.03.004 · Cited by 881
Traumatic stress: effects on the brain
Bremner, J. D. (2006) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2006.8.4/jbremner · Cited by 738
Self-citation
Sex differences in stress-related psychiatric disorders: neurobiological perspectives
Bangasser, D. A., & Valentino, R. J. (2014) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2014.03.008 · Cited by 737
Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus
Kheirbek, M. A., Drew, L. J., Burghardt, N. S., Costantini, D. O., Tannenholz, L., Ahmari, S. E., Zeng, H., Fenton, A. A., & Hen, R. (2013) · Neuron · doi:10.1016/j.neuron.2012.12.038 · Cited by 713
Neuroimaging of child abuse: a critical review
Hart, H., & Rubia, K. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00052 · Cited by 660
A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing
Tottenham, N. (2009) · Frontiers in Human Neuroscience · doi:10.3389/neuro.09.068.2009 · Cited by 651
Disturbed dreaming, posttraumatic stress disorder, and affect distress: A review and neurocognitive model.
Levin, R., & Nielsen, T. A. (2007) · Psychological Bulletin · doi:10.1037/0033-2909.133.3.482 · Cited by 554
Neural correlates of socioeconomic status in the developing human brain
Noble, K. G., Houston, S. M., Kan, E., & Sowell, E. R. (2012) · Developmental Science · doi:10.1111/j.1467-7687.2012.01147.x · Cited by 542
A quantitative meta-analysis of neurocognitive functioning in posttraumatic stress disorder.
Scott, J. C., Matt, G. E., Wrocklage, K. M., Crnich, C., Jordan, J., Southwick, S. M., Krystal, J. H., & Schweinsburg, B. C. (2015) · Psychological Bulletin · doi:10.1037/a0038039 · Cited by 513
Neurogenesis and generalization: a new approach to stratify and treat anxiety disorders
Kheirbek, M. A., Klemenhagen, K. C., Sahay, A., & Hen, R. (2012) · Nature Neuroscience · doi:10.1038/nn.3262 · Cited by 538
Lifecourse Social Conditions and Racial and Ethnic Patterns of Cognitive Aging
Glymour, M. M., & Manly, J. J. (2008) · Neuropsychology Review · doi:10.1007/s11065-008-9064-z · Cited by 481
Smaller hippocampal volume in posttraumatic stress disorder: a multisite ENIGMA-PGC study: subcortical volumetry results from posttraumatic stress disorder consortia
Logue, M. W., van Rooij, S. J. H., Dennis, E. L., Davis, S. L., Hayes, J. P., Stevens, J. S., Densmore, M., Haswell, C. C., Ipser, J., Koch, S. B. J., et al. (2018) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.09.006 · Cited by 487
Context Processing and the Neurobiology of Post-Traumatic Stress Disorder
Liberzon, I., & Abelson, J. L. (2016) · Neuron · doi:10.1016/j.neuron.2016.09.039 · Cited by 489
Hippocampal and amygdala volumes in children and adults with childhood maltreatment-related posttraumatic stress disorder: a meta-analysis
Woon, F. L., & Hedges, D. W. (2008) · Hippocampus · doi:10.1002/hipo.20437 · Cited by 416
Hippocampal volume deficits associated with exposure to psychological trauma and posttraumatic stress disorder in adults: A meta-analysis
Woon, F. L., Sood, S., & Hedges, D. W. (2010) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2010.06.016 · Cited by 410
Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders
Radua, J., van den Heuvel, O. A., Surguladze, S., & Mataix-Cols, D. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2010.70 · Cited by 400
Chronic stress: Implications for neuronal morphology, function and neurogenesis
Joëls, M., Karst, H., Krugers, H. J., & Lucassen, P. J. (2007) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2007.04.001 · Cited by 381
A systematic review and meta-analysis of magnetic resonance imaging measurement of structural volumes in posttraumatic stress disorder
O'Doherty, D. C. M., Chitty, K. M., Saddiqui, S., Bennett, M. R., & Lagopoulos, J. (2015) · Psychiatry Research: Neuroimaging · doi:10.1016/j.pscychresns.2015.01.002 · Cited by 375
Structural and functional plasticity of the human brain in posttraumatic stress disorder
Bremner, J. D., Elzinga, B. M., Schmahl, C. G., & Vermetten, E. H. G. J. M. (2007) · Progress in brain research · doi:10.1016/s0079-6123(07)67012-5 · Cited by 379
Self-citation
Evidence for Acquired Pregenual Anterior Cingulate Gray Matter Loss from a Twin Study of Combat-Related Posttraumatic Stress Disorder
Kasai, K., Yamasue, H., Gilbertson, M. W., Shenton, M. E., Rauch, S. L., & Pitman, R. K. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.06.022 · Cited by 377
Reduced Medial Prefrontal Cortex Volume in Adults Reporting Childhood Emotional Maltreatment
van Harmelen, A.-L., van Tol, M.-J., van der Wee, N. J. A., Veltman, D. J., Aleman, A., Spinhoven, P., van Buchem, M. A., Zitman, F. G., Penninx, B. W. J. H., & Elzinga, B. M. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.06.011 · Cited by 362
Prospective reports of chronic life stress predict decreased grey matter volume in the hippocampus
Gianaros, P. J., Jennings, J. R., Sheu, L. K., Greer, P. J., Kuller, L. H., & Matthews, K. A. (2007) · NeuroImage · doi:10.1016/j.neuroimage.2006.10.045 · Cited by 324
Magnetic Resonance Imaging of Hippocampal Subfields in Posttraumatic Stress Disorder
Wang, Z., Neylan, T. C., Mueller, S. G., Lenoci, M., Truran, D., Marmar, C. R., Weiner, M. W., & Schuff, N. W. (2010) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.205 · Cited by 307
Functional neuroimaging studies of post-traumatic stress disorder
Hughes, K. C., & Shin, L. M. (2011) · Expert Review of Neurotherapeutics · doi:10.1586/ern.10.198 · Cited by 290
Posttraumatic stress disorder: An empirical evaluation of core assumptions
Rosen, G. M., & Lilienfeld, S. O. (2007) · Clinical Psychology Review · doi:10.1016/j.cpr.2007.12.002 · Cited by 282
Mild traumatic brain injury and posttraumatic stress disorder in returning veterans: Perspectives from cognitive neuroscience
Vasterling, J. J., Verfaellie, M. H., & Sullivan, K. D. (2009) · Clinical Psychology Review · doi:10.1016/j.cpr.2009.08.004 · Cited by 279
A Systematic Review of Treatments for Post-Traumatic Stress Disorder Among Refugees and Asylum-Seekers
Crumlish, N., & O'Rourke, K. (2010) · Journal of Nervous & Mental Disease · doi:10.1097/nmd.0b013e3181d61258 · Cited by 264
Gray Matter Correlates of Posttraumatic Stress Disorder: A Quantitative Meta-Analysis
Kühn, S., & Gallinat, J. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.06.029 · Cited by 259
Symptomatology and psychopathology of mental health problems after disaster.
Foa, E. B., Stein, D. J., & McFARLANE, A. C. (2006) · PubMed · Cited by 244
Consistent impaired verbal memory in PTSD: a meta-analysis.
Johnsen, G. E., & Asbjørnsen, A. (2008) · Journal of Affective Disorders · doi:10.1016/j.jad.2008.02.007 · Cited by 243
The Role of Glutamate in Anxiety and Related Disorders
Cortese, B. M., & Phan, K. L. (2005) · CNS Spectrums · doi:10.1017/s1092852900010427 · Cited by 231
Perceived Stress and Change in Cognitive Function Among Adults 65 Years and Older
Aggarwal, N. T., Wilson, R. S., Beck, T. L., Rajan, K. B., de Leon, C. F. M., Evans, D. A., & Everson‐Rose, S. A. (2013) · Psychosomatic Medicine · doi:10.1097/psy.0000000000000016 · Cited by 246
Biomarkers for the Diagnosis, Prognosis, and Evaluation of Treatment Efficacy for Traumatic Brain Injury
Dash, P. K., Zhao, J., Hergenroeder, G. W., & Moore, A. N. (2010) · Neurotherapeutics · doi:10.1016/j.nurt.2009.10.019 · Cited by 221
Hippocampal dysfunction effects on context memory: Possible etiology for posttraumatic stress disorder
Acheson, D. T., Gresack, J. E., & Risbrough, V. B. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.04.029 · Cited by 221
Neuropsychological Findings in Pediatric Maltreatment: Relationship of PTSD, Dissociative Symptoms, and Abuse/Neglect Indices to Neurocognitive Outcomes
De Bellis, M. D., Woolley, D. P., & Hooper, S. R. (2013) · Child Maltreatment · doi:10.1177/1077559513497420 · Cited by 183
Neuroimaging resilience to stress: a review
van der Werff, S. J. A., van den Berg, S. M., Pannekoek, J. N., Elzinga, B. M., & van der Wee, N. J. A. (2013) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2013.00039 · Cited by 188
Understanding posttraumatic stress disorder through fear conditioning, extinction and reconsolidation
Careaga, M. B. L., Girardi, C. E. N., & Suchecki, D. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.08.023 · Cited by 193
Genetics of Post-Traumatic Stress Disorder: Review and Recommendations for Genome-Wide Association Studies
Cornelis, M. C., Nugent, N. R., Amstadter, A. B., & Koenen, K. C. (2010) · Current Psychiatry Reports · doi:10.1007/s11920-010-0126-6 · Cited by 183
Meta-Analysis of 89 Structural MRI Studies in Posttraumatic Stress Disorder and Comparison With Major Depressive Disorder
Bromis, K., Calem, M., Reinders, A. A. T. S., Williams, S. C. R., & Kempton, M. J. (2018) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2018.17111199 · Cited by 177
Circadian Clock and Stress Interactions in the Molecular Biology of Psychiatric Disorders
Landgraf, D., McCarthy, M. J., & Welsh, D. K. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0483-7 · Cited by 181
Stress, PTSD, and dementia
Greenberg, M. S., Tanev, K., Marin, M., & Pitman, R. K. (2014) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.04.008 · Cited by 161
Thinner prefrontal cortex in veterans with posttraumatic stress disorder
Geuze, E., Westenberg, H. G. M., Heinecke, A., de Kloet, C. S., Goebel, R., & Vermetten, E. H. G. J. M. (2008) · NeuroImage · doi:10.1016/j.neuroimage.2008.03.007 · Cited by 168
Neuroimaging in Posttraumatic Stress Disorder and Other Stress-Related Disorders
Bremner, J. D. (2007) · Neuroimaging Clinics of North America · doi:10.1016/j.nic.2007.07.003 · Cited by 174
Self-citation
Human amygdala development in the absence of species‐expected caregiving
Tottenham, N. (2012) · Developmental Psychobiology · doi:10.1002/dev.20531 · Cited by 149
Different neural modifications underpin PTSD after different traumatic events: an fMRI meta-analytic study
Boccia, M., D’Amico, S., Bianchini, F., Marano, A., Giannini, A. M., & Piccardi, L. (2015) · Brain Imaging and Behavior · doi:10.1007/s11682-015-9387-3 · Cited by 155
Genetics of PTSD: fear conditioning as a model for future research
Amstadter, A. B., Nugent, N. R., & Koenen, K. C. (2009) · Psychiatric Annals · doi:10.3928/00485713-20090526-01 · Cited by 150
Animal models of post-traumatic stress disorder: face validity
Goswami, S., Rodríguez-Sierra, O. E., Cascardi, M. A., & Paré, D. (2013) · Frontiers in Neuroscience · doi:10.3389/fnins.2013.00089 · Cited by 165
Post-traumatic stress disorder and declarative memory functioning: a review
Samuelson, K. W. (2011) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2011.13.2/ksamuelson · Cited by 157
Neurobiology of comorbid post‐traumatic stress disorder and alcohol‐use disorder
Gilpin, N. W., & Weiner, J. L. (2016) · Genes Brain & Behavior · doi:10.1111/gbb.12349 · Cited by 154
Strategies for dementia prevention: latest evidence and implications
Rakesh, G., Szabo, S. T., Alexopoulos, G. S., & Zannas, A. S. (2017) · Therapeutic Advances in Chronic Disease · doi:10.1177/2040622317712442 · Cited by 164
Hippocampal volume varies with educational attainment across the life-span
Noble, K. G., Grieve, S. M., Korgaonkar, M. S., Engelhardt, L. E., Griffith, E. Y., Williams, L. M., & Brickman, A. M. (2012) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2012.00307 · Cited by 154
Smaller hippocampal volume as a vulnerability factor for the persistence of post-traumatic stress disorder
van Rooij, S. J. H., Kennis, M., Sjouwerman, R., van den Heuvel, M. P., Kahn, R. S., & Geuze, E. (2015) · Psychological Medicine · doi:10.1017/s0033291715000707 · Cited by 145
AMYGDALA RESPONSE TO NEGATIVE STIMULI PREDICTS PTSD SYMPTOM ONSET FOLLOWING A TERRORIST ATTACK
McLaughlin, K. A., Busso, D. S., Duys, A., Green, J. G., Alves, S., Way, M., & Sheridan, M. A. (2014) · Depression and Anxiety · doi:10.1002/da.22284 · Cited by 152
Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety
Shi, H., Wang, S., Wang, X., Zhang, R.-X., & Zhu, L. (2023) · Neuroscience Bulletin · doi:10.1007/s12264-023-01020-1 · Cited by 151
Hippocampal volume differences in gulf war veterans with current versus lifetime posttraumatic stress disorder symptoms
Apfel, B. A., Ross, J., Hlavin, J., Meyerhoff, D. J., Metzler, T. J., Marmar, C. R., Weiner, M. W., Schuff, N., & Neylan, T. C. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2010.09.044 · Cited by 139
Post-traumatic stress disorder: medicine and politics
Stein, D. J., Seedat, S., Iversen, A. C., & Wessely, S. C. (2007) · The Lancet · doi:10.1016/s0140-6736(07)60075-0 · Cited by 146
Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders
Hakamata, Y., Suzuki, Y., Kobashikawa, H., & Hori, H. (2022) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2022.100994 · Cited by 159
How does childhood maltreatment influence ensuing cognitive functioning among people with the exposure of childhood maltreatment? A systematic review of prospective cohort studies
Su, Y., D’Arcy, C., Yuan, S., & Meng, X. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.04.026 · Cited by 154
Neuroinflammation and the Immune-Kynurenine Pathway in Anxiety Disorders
Kim, Y., & Jeon, S. W. (2018) · Current Neuropharmacology · doi:10.2174/1570159x15666170913110426 · Cited by 133
A review on brain structures segmentation in magnetic resonance imaging
González-Villà, S., Oliver, A., Valverde, S., Wang, L., Reyer Zwiggelaar, A., & Lladó, X. (2016) · Artificial Intelligence in Medicine · doi:10.1016/j.artmed.2016.09.001 · Cited by 135
Abnormal Fear Memory as a Model for Posttraumatic Stress Disorder
Desmedt, A., Marighetto, A., & Piazza, P. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.06.017 · Cited by 140
Neuropsychological Sequelae of PTSD and TBI Following War Deployment among OEF/OIF Veterans
Dolan, S., Martindale, S., Robinson, J., Kimbrel, N. A., Meyer, E. C., Kruse, M. I., Morissette, S. B., Young, K. A., & Gulliver, S. B. (2012) · Neuropsychology Review · doi:10.1007/s11065-012-9190-5 · Cited by 126
Genetic approaches to understanding post-traumatic stress disorder
Almli, L. M., Fani, N., Smith, A. K., & Ressler, K. J. (2014) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713001090 · Cited by 124
Deficient fear extinction memory in posttraumatic stress disorder
Wicking, M., Steiger-White, F., Nees, F., Diener, S. J., Grimm, O., Ruttorf, M., Schad, L. R., Winkelmann, T., Wirtz, G., & Flor, H. (2016) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2016.09.016 · Cited by 139
Amygdala Volume in Adults with Posttraumatic Stress Disorder: A Meta-Analysis
Woon, F. L., & Hedges, D. W. (2009) · The Journal of Neuropsychiatry and Clinical Neurosciences · doi:10.1176/jnp.2009.21.1.5 · Cited by 120
Psychobiology of childhood maltreatment: effects of allostatic load?
Grassi-Oliveira, R., Ashy, M., & Stein, L. M. (2008) · Revista Brasileira de Psiquiatria · doi:10.1590/s1516-44462008000100012 · Cited by 116
The Relationship Between Cognitive and Brain Changes in Posttraumatic Stress Disorder
Bremner, J. D. (2006) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1364.008 · Cited by 122
Self-citation
Hippocampal and amygdala volumes in adults with posttraumatic stress disorder secondary to childhood abuse or maltreatment: A systematic review
Ahmed-Leitao, F., Spies, G., van den Heuvel, L. L., & Seedat, S. (2016) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2016.09.008 · Cited by 123
The urban environment and mental disorders
Galea, S., Uddin, M., & Koenen, K. C. (2011) · Epigenetics · doi:10.4161/epi.6.4.14944 · Cited by 119
Learning not to Fear: Neural Correlates of Learned Safety
Kong, E., Monje, F. J., Hirsch, J., & Pollak, D. D. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.191 · Cited by 113
Demographic, Maltreatment, and Neurobiological Correlates of PTSD Symptoms in Children and Adolescents
Bellis, M. D. D., Hooper, S. R., Woolley, D. P., & Shenk, C. E. (2009) · Journal of Pediatric Psychology · doi:10.1093/jpepsy/jsp116 · Cited by 121
Neuropsychological task performance in bipolar spectrum illness: genetics, alcohol abuse, medication and childhood trauma
Savitz, J. B., van der Merwe, L., Stein, D. J., Solms, M., & Ramesar, R. (2008) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00591.x · Cited by 111
Neuroimaging research in posttraumatic stress disorder – Focus on amygdala, hippocampus and prefrontal cortex
Henigsberg, N., Kalember, P., Petrović, Z. K., & Šečić, A. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2018.11.003 · Cited by 105
Twin studies of posttraumatic stress disorder: Differentiating vulnerability factors from sequelae
Kremen, W. S., Koenen, K. C., Afari, N., & Lyons, M. J. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.03.012 · Cited by 120
Manual validation of FreeSurfer's automated hippocampal segmentation in normal aging, mild cognitive impairment, and Alzheimer Disease subjects
Sánchez‐Benavides, G., Gómez‐Ansón, B., Sainz, A., Vives‐Gilabert, Y., Delfino, M., & Peña‐Casanova, J. (2010) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2009.10.011 · Cited by 109
Post‐traumatic stress disorder and risk of dementia among members of a health care delivery system
Flatt, J. D., Gilsanz, P., Quesenberry, C. P., Albers, K. B., & Whitmer, R. A. (2017) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2017.04.014 · Cited by 105
Neurobiology of emotional trauma
Giotakos, O. (2020) · Psychiatriki · doi:10.22365/jpsych.2020.312.162 · Cited by 130
Biomarkers in Posttraumatic Stress Disorder: Overview and Implications for Future Research
Schmidt, U., Kaltwasser, S. F., & Wotjak, C. T. (2013) · Disease Markers · doi:10.1155/2013/835876 · Cited by 103
The Neurocircuitry of Fear, Stress, and Anxiety Disorders
Shin, L. M., & Liberzon, I. (2011) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/foc.9.3.foc311 · Cited by 105
Amygdala and hippocampus volumes are differently affected by childhood trauma in patients with bipolar disorders and healthy controls
Janiri, D., Sani, G., Rossi, P. D., Piras, F., Iorio, M., Banaj, N., Giuseppin, G., Spinazzola, E., Maggiora, M., Ambrosi, E., et al. (2017) · Bipolar Disorders · doi:10.1111/bdi.12516 · Cited by 99
Nicotine modulation of fear memories and anxiety: Implications for learning and anxiety disorders
Kutlu, M. G., & Gould, T. J. (2015) · Biochemical Pharmacology · doi:10.1016/j.bcp.2015.07.029 · Cited by 97
Pretrauma and Posttrauma Neurocognitive Functioning and PTSD Symptoms in a Community Sample of Young Adults
Parslow, R. A., & Jorm, A. F. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.3.509 · Cited by 134
Can pharmacological and psychological treatment change brain structure and function in PTSD? A systematic review
Thomaes, K., Dorrepaal, E., Draijer, N., Jansma, E. P., Veltman, D. J., & van Balkom, A. J. L. M. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2013.11.002 · Cited by 105
Elucidating Pretreatment Cognitive Impairment in Breast Cancer Patients: The Impact of Cancer-related Post-traumatic Stress
Hermelink, K., Voigt, V., Kaste, J., Neufeld, F., Wuerstlein, R., Bühner, M., Münzel, K., Rjosk-Dendorfer, D., Grandl, S., Braun, M., et al. (2015) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djv099 · Cited by 105
Anatomical deficits in adult posttraumatic stress disorder: A meta-analysis of voxel-based morphometry studies
Meng, Y., Qiu, C., Zhu, H., Lama, S., Lui, S., Gong, Q., & Zhang, W. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.05.021 · Cited by 97
Hippocampal volume in first episode and recurrent depression
Kronmüller, K., Schröder, J., Köhler, S., Götz, B., Victor, D., Unger, J., Giesel, F., Magnotta, V. A., Mundt, C., Essig, M., et al. (2009) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2008.08.001 · Cited by 94
Borderline Personality Disorder Recent research findings have contributed to an improved understanding and treatment of borderline personality
Leichsenring, F., Leibing, E., Kruse, J., New, A. S., & Leweke, F. (2013) · Cited by 93
Hippocampus Glutamate and N-Acetyl Aspartate Markers of Excitotoxic Neuronal Compromise in Posttraumatic Stress Disorder
Rosso, I. M., Crowley, D. J., Silveri, M. M., Rauch, S. L., & Jensen, J. E. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2017.32 · Cited by 97
Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder
Boven, R. W. V., Harrington, G. S., Hackney, D. B., Ebel, A., Gauger, G. E., Bremner, J. D., D’Esposito, M., Detre, J. A., Haacke, E. M., Jack, C. R., et al. (2009) · The Journal of Rehabilitation Research and Development · doi:10.1682/jrrd.2008.12.0161 · Cited by 93
Self-citation
Problematic alcohol use and reduced hippocampal volume: a meta-analytic review
Wilson, S., Bair, J. L., Thomas, K. M., & Iacono, W. G. (2017) · Psychological Medicine · doi:10.1017/s0033291717000721 · Cited by 90
Early-life stress, corpus callosum development, hippocampal volumetrics, and anxious behavior in male nonhuman primates
Jackowski, A. P., Perera, T. D., Abdallah, C. G., Garrido, G. J., Tang, C. Y., Martínez, J. A. B., Mathew, S. J., Gorman, J. M., Rosenblum, L. A., Smith, E. L., et al. (2011) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2010.11.006 · Cited by 89
Circadian rhythms in the blood–brain barrier: impact on neurological disorders and stress responses
Schurhoff, N. A., & Toborek, M. J. (2023) · Molecular Brain · doi:10.1186/s13041-023-00997-0 · Cited by 95
Single-prolonged stress induced mitochondrial-dependent apoptosis in hippocampus in the rat model of post-traumatic stress disorder
Li, X. M., Han, F., Liu, D. J., & Shi, Y. (2010) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2010.07.001 · Cited by 88
Neuropsychological performance is related to current social and occupational functioning in veterans with posttraumatic stress disorder
Geuze, E., Vermetten, E. H. G. J. M., de Kloet, C. S., Hijman, R., & Westenberg, H. G. M. (2008) · Depression and Anxiety · doi:10.1002/da.20476 · Cited by 97
Stress-induced change of mitochondria membrane potential regulated by genomic and non-genomic GR signaling: A possible mechanism for hippocampus atrophy in PTSD
Zhang, L., Zhou, R., Li, X., Ursano, R. J., & Li, H. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2005.11.041 · Cited by 87
Oxytocin receptor DNA methylation and alterations of brain volumes in maltreated children
Fujisawa, T. X., Nishitani, S., Takiguchi, S., Shimada, K., Smith, A. K., & Tomoda, A. (2019) · Neuropsychopharmacology · doi:10.1038/s41386-019-0414-8 · Cited by 85

Authors: Kitayama, N., Vaccarino, V., Kutner, M., Weiss, P., & Bremner, J. D.
Affiliations: Emory University (US)
Corresponding author: Kitayama, Noriyuki
ORCID: Vaccarino, Viola
Kutner, Michael
Bremner, J. Douglas
Venue: Journal of Affective Disorders
Publisher: Elsevier BV
Published: 2005-09
Volume: 88
Issue: 1
Pages: 79-86
ISSN: 0165-0327 (ISSN-L)
DOI: 10.1016/j.jad.2005.05.014
OpenAlex: W2145267709
Cited by: 423
References: 49
Citations by year: 2026: 9 · 2025: 7 · 2024: 16 · 2023: 13 · 2022: 16 · 2021: 13 · 2020: 20 · 2019: 22 · 2018: 24 · 2017: 28 · 2016: 27 · 2015: 26 · 2014: 29 · 2013: 36 · 2012: 19
FWCI: 2.85
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Affective Disorders (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Clinical Psychology › Posttraumatic Stress Disorder Research
Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
Social Sciences › Psychology › Clinical Psychology › Child Abuse and Trauma
Keywords: post-traumatic stress disorder, hippocampal volume, hippocampal atrophy, chronic PTSD, brain structural changes, trauma exposure, hippocampus
MeSH terms: Adult, Chronic Disease, Dominance, Cerebral, Female, Hippocampus, Humans, Magnetic Resonance Imaging, Male, Reference Values, Stress Disorders, Post-Traumatic

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: A meta-analysis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks