Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: a randomized controlled trial

Fogliati, V.J.; Dear, B.F.; Staples, L.G.; Terides, M.D.; Sheehan, J.; Johnston, L.; Kayrouz, R.; Dear, R.; McEvoy, P.M.; Titov, N.

doi:10.1016/j.janxdis.2016.03.005

Cited by 86Digital Mental Health InterventionsAnxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesPersonality Disorders and Psychopathology

Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: a randomized controlled trial

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Fogliati, V.J., Dear, B.F., Staples, L.G., Terides, M.D., Sheehan, J., Johnston, L., Kayrouz, R., Dear, R. +2 more·2016·Journal of Anxiety Disorders

DOI 10.1016/j.janxdis.2016.03.005

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Abstract

Transdiagnostic cognitive behaviour therapy (TD-CBT) aims to target the symptoms of multiple disorders whereas disorder-specific CBT (DS-CBT) targets the symptoms of principal disorders. This study compared the relative benefits of internet-delivered TD-CBT and DS-CBT when provided in clinician-guided (CG-CBT) and self-guided (SG-CBT) formats for people with a principal diagnosis of Panic Disorder (PD). Participants (n=145) were randomly allocated to receive TD-CBT or DS-CBT and CG-CBT or SG-CBT. Large reductions in symptoms of PD (Cohen's d ≥ 0.71; avg. reduction ≥ 36%) and moderate-to-large reductions in symptoms of comorbid depression (Cohen's d ≥ 0.71; avg. reduction ≥ 33%), generalised anxiety disorder (Cohen's d ≥ 0.91; avg. reduction ≥ 34%) and social anxiety disorder (Cohen's d ≥ 0.50; avg. reduction ≥ 15%) were found over the 24-month follow-up period. Highlighting their efficacy and acceptability, no marked and consistent differences were observed between TD-CBT and DS-CBT or CG-CBT and DS-CBT.

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Internet-based cognitive behavioral therapy programs reduce symptoms across a range of mental disorders, including post-traumatic stress disorder, social anxiety disorder, and panic disorder.
“Internet-based cognitive behavioral therapy programs have been shown to reduce symptoms across a range of mental disorders, including post-traumatic stress disorder (1), social anxiety disorder (2), and panic disorder (3), among others.”
From Improving Acceptability and Uptake Behavior for Internet-Based Cognitive-Behavioral Therapy (2021) · cites this paper as [3]
The PSP Wellbeing Course was adapted from the transdiagnostic ICBT program called the Wellbeing Course, which was developed for use in the general population by eCentre Clinic at Macquarie University, Australia.
“The PSP Wellbeing Course was adapted from a transdiagnostic ICBT program called the Wellbeing Course, which was developed for use in the general population by eCentre Clinic at Macquarie University, Australia [28-32].”
From Initial Outcomes of Transdiagnostic Internet-Delivered Cognitive Behavioral Therapy Tailored to Public Safety Personnel: Longitudinal Observational Study (2021) · cites this paper as [30]

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Should our major classifications of mental disorders be revised?
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TRANSDIAGNOSTIC INTERNET TREATMENT FOR ANXIETY AND DEPRESSION
Titov, N., Dear, B. F., Johnston, L., & Terides, M. D. (2012) · Revista de Psicopatología y Psicología Clínica · Cited by 31 · see citing works
Further Study of the Psychometric Qualities of a Brief Screening Tool for Social Phobia (MINI-SPIN) Applied to Clinical and Nonclinical Samples
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Cognitive-behavioural treatment for panic
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Mewton, L., Wong, N., & Andrews, G. (2012). The effectiveness of internet cognitive behavioural therapy for generalized anxiety disorder in clinical practice. Depress Anxiety, 29(10), 843-849.

Sorted by citations

Digital interventions for the treatment of depression: a meta-analytic review
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Psychometric properties and clinical utility of brief measures of depression, anxiety, and general distress: The PHQ-2, GAD-2, and K-6
Staples, L. G., Dear, B. F., Gandy, M., Fogliati, V., Fogliati, R., Karin, E., Nielssen, O., & Titov, N. (2019) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2018.11.003 · Cited by 405 · see citing works
Self-citation
Internet-delivered transdiagnostic and tailored cognitive behavioral therapy for anxiety and depression: a systematic review and meta-analysis of randomized controlled trials
Păsărelu, C. R., Andersson, G., Bergman Nordgren, L., & Dobrean, A. (2017) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2016.1231219 · Cited by 335 · see citing works
Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial
Dear, B. F., Staples, L. G., Terides, M. D., Karin, E., Zou, J., Johnston, L., Gandy, M., Fogliati, V. J., Wootton, B. M., McEvoy, P. M., et al. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2015.09.003 · Cited by 230 · see citing works
Self-citation
Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial
Titov, N., Dear, B. F., Staples, L. G., Terides, M. D., Karin, E., Sheehan, J., Johnston, L., Gandy, M., Fogliati, V. J., Wootton, B. M., et al. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2015.08.002 · Cited by 223 · see citing works
Internet- and mobile-based interventions for anxiety disorders: A meta-analytic review of intervention components
Domhardt, M., Geßlein, H., von Rezori, R. E., & Baumeister, H. (2019) · Depression and Anxiety · doi:10.1002/da.22860 · Cited by 218 · see citing works
Two decades of digital interventions for anxiety disorders: a systematic review and meta-analysis of treatment effectiveness
Pauley, D., Cuijpers, P., Papola, D., Miguel, C., & Karyotaki, E. (2021) · Psychological Medicine · doi:10.1017/s0033291721001999 · Cited by 170 · see citing works
Impact of guidance on intervention adherence in computerised interventions for mental health problems: a meta-analysis
Musiat, P., Johnson, C., Atkinson, M., Wilksch, S., & Wade, T. (2022) · Psychological Medicine · doi:10.1017/s0033291721004621 · Cited by 166 · see citing works
Guided and unguided Acceptance and Commitment Therapy for social anxiety disorder and/or panic disorder provided via the Internet and a smartphone application: A randomized controlled trial
Ivanova, E., Lindner, P., Ly, K. H., Dahlin, M., Vernmark, K., Andersson, G., & Carlbring, P. (2016) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2016.09.012 · Cited by 165 · see citing works
Internet-delivered cognitive behaviour therapy for chronic health conditions: A systematic review and meta-analysis
Mehta, S., Peynenburg, V. A., & Hadjistavropoulos, H. D. (2019) · Journal of Behavioral Medicine · doi:10.1007/s10865-018-9984-x · Cited by 153 · see citing works
From Research to Practice: Ten Lessons in Delivering Digital Mental Health Services
Titov, N., Hadjistavropoulos, H. D., Nielssen, O. B., Mohr, D. C., Andersson, G., & Dear, B. F. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8081239 · Cited by 117 · see citing works
Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for social anxiety disorder and comorbid disorders: a randomized controlled trial
Dear, B. F., Staples, L. G., Terides, M. D., Fogliati, V. J., Sheehan, J., Johnston, L., Kayrouz, R., Dear, R., McEvoy, P. M., & Titov, N. (2016) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2016.05.004 · Cited by 114 · see citing works
Effects of a transdiagnostic unguided Internet intervention (‘velibra’) for anxiety disorders in primary care: results of a randomized controlled trial
Berger, T., Urech, A., Krieger, T., Stolz, T., Schulz, A., Vincent, A., Moser, C. T., Moritz, S., & Meyer, B. (2017) · Psychological Medicine · doi:10.1017/s0033291716002270 · Cited by 98 · see citing works
“Although transdiagnostic and tailored approaches may not be more effective than disorder-specific treatments (Berger et al. 2014; Dear et al. 2015; Fogliati et al. 2016), they have other advantages, particularly when delivered in primary care.”
Background
Cognitive behavioral therapy, mindfulness-based cognitive therapy and acceptance commitment therapy for anxiety disorders: Integrating traditional with digital treatment approaches
Apolinário-Hagen, J., Drüge, M., & Fritsche, L. (2020) · Advances in Experimental Medicine and Biology · doi:10.1007/978-981-32-9705-0_17 · Cited by 100 · see citing works
Treating anxiety and depression in young adults: a randomised controlled trial comparing clinician-guided versus self-guided Internet-delivered cognitive behavioural therapy
Dear, B. F., Fogliati, V. J., Fogliati, R., Johnson, B., Boyle, O., Karin, E., Gandy, M., Kayrouz, R., Staples, L. G., & Titov, N. (2018) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867417738055 · Cited by 93 · see citing works
Eficacia de la terapia cognitivo conductual transdiagnóstica en el tratamiento de la ansiedad y la depresión en adultos, niños y adolescentes: Un meta-análisis
García-Escalera, J., Chorot, P., Valiente, R. M., Reales, J. M., & Sandín, B. (2017) · Revista de Psicopatología y Psicología Clínica · doi:10.5944/rppc.vol.21.num.3.2016.17811 · Cited by 94 · see citing works
A systematic review and meta-analysis of transdiagnostic cognitive behavioural therapies for emotional disorders
Schaeuffele, C., Meine, L. E., Schulz, A., Weber, M. C., Moser, A., Paersch, C., Recher, D., Boettcher, J., Renneberg, B., Flückiger, C., et al. (2024) · Nature Human Behaviour · doi:10.1038/s41562-023-01787-3 · Cited by 91 · see citing works
Metacognitive therapy versus disorder-specific CBT for comorbid anxiety disorders: A randomized controlled trial
Johnson, S. U., Hoffart, A., Nordahl, H. M., & Wampold, B. E. (2017) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2017.06.004 · Cited by 67 · see citing works
Internet-based treatment for panic disorder: A three-arm randomized controlled trial comparing guided (via real-time video sessions) with unguided self-help treatment and a waitlist control. PAXPD study results
Ciuca, A. M., Berger, T., Crişan, L. G., & Miclea, M. (2018) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2018.03.009 · Cited by 58 · see citing works
Two Novel Cognitive Behavioral Therapy–Based Mobile Apps for Agoraphobia: Randomized Controlled Trial
Christoforou, M., Sáez Fonseca, J. A., & Tsakanikos, E. (2017) · Journal of Medical Internet Research · doi:10.2196/jmir.7747 · Cited by 48 · see citing works
Comparative efficacy and acceptability of psychotherapies for panic disorder with or without agoraphobia: systematic review and network meta-analysis of randomised controlled trials
Papola, D., Ostuzzi, G., Tedeschi, F., Gastaldon, C., Purgato, M., Giovane, C. D., Pompoli, A., Pauley, D., Karyotaki, E., Sijbrandij, M., et al. (2021) · The British Journal of Psychiatry · doi:10.1192/bjp.2021.148 · Cited by 56 · see citing works
Acceptability of Digital Mental Health Interventions for Depression and Anxiety: Systematic Review
Lau, C. K. Y., Saad, A., Camara, B., Rahman, D., & Bolea-Alamanac, B. (2024) · Journal of Medical Internet Research · doi:10.2196/52609 · Cited by 51 · see citing works
Self-guided internet–delivered cognitive behavior therapy (ICBT) for obsessive-compulsive symptoms: A randomized controlled trial
Wootton, B. M., Karin, E., Titov, N., & Dear, B. F. (2019) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2019.102111 · Cited by 51 · see citing works
Initial Outcomes of Transdiagnostic Internet-Delivered Cognitive Behavioral Therapy Tailored to Public Safety Personnel: Longitudinal Observational Study
Hadjistavropoulos, H. D., McCall, H. C., Thiessen, D. L., Huang, Z., Carleton, R. N., Dear, B. F., & Titov, N. (2021) · Journal of Medical Internet Research · doi:10.2196/27610 · Cited by 42 · see citing works
Self-citation
A web-based transdiagnostic intervention for affective and mood disorders: randomized controlled trial.
Tulbure, B. T., Rusu, A., Sava, F. A., Sălăgean, N., & Farchione, T. J. (2018) · JMIR Mental Health · doi:10.2196/mental.8901 · Cited by 43 · see citing works
Internet-delivered cognitive behavioral therapy for panic disorder with or without agoraphobia: a systematic review and meta-analysis
Stech, E. P., Lim, J., Upton, E. L., & Newby, J. M. (2020) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2019.1628808 · Cited by 43 · see citing works
A randomized controlled trial of a transdiagnostic Internet intervention for individuals with panic and phobias – one size fits all
Schröder, J., Jelinek, L., & Moritz, S. (2017) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/j.jbtep.2016.05.002 · Cited by 32 · see citing works
The Effects of Internet-Based Cognitive Behavioral Therapy for Suicidal Ideation or Behaviors on Depression, Anxiety, and Hopelessness in Individuals With Suicidal Ideation: Systematic Review and Meta-Analysis of Individual Participant Data
Sander, L., Beisemann, M., Doebler, P., Micklitz, H. M., Kerkhof, A. J. F. M., Cuijpers, P. J., Batterham, P. J., Calear, A. L., Christensen, H. M., Jaegere, E. D., et al. (2023) · Journal of Medical Internet Research · doi:10.2196/46771 · Cited by 34 · see citing works
Remote cognitive behavioral therapy for panic disorder: A meta-analysis.
Efron, G., & Wootton, B. (2021) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2021.102385 · Cited by 27 · see citing works
Improving Acceptability and Uptake Behavior for Internet-Based Cognitive-Behavioral Therapy
Molloy, A., Ellis, D. M., Su, L., & Anderson, P. L. (2021) · Frontiers in Digital Health · doi:10.3389/fdgth.2021.653686 · Cited by 29 · see citing works
Internet-delivered treatment for young adults with anxiety and depression: Evaluation in routine clinical care and comparison with research trial outcomes
Staples, L., Dear, B. F., Johnson, B., Fogliati, V. J., Gandy, M., Fogliati, R., Nielssen, O. B., & Titov, N. (2019) · Journal of Affective Disorders · doi:10.1016/j.jad.2019.05.058 · Cited by 31 · see citing works
Comorbidity and diagnosis distribution in transdiagnostic treatments for emotional disorders: A systematic review of randomized controlled trials
González-Robles, A., Díaz‐García, A., Miguel, C., García‐Palacios, A., & Botella, C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0207396 · Cited by 31 · see citing works
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Polak, M., Tanzer, N. K., Bauernhofer, K., & Andersson, G. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100364 · Cited by 26 · see citing works
Aplicación grupal del Protocolo Unificado para el tratamiento transdiagnóstico de los trastornos emocionales en población argentina
Grill, S. S., Castañeiras, C. E., & Fasciglione, M. P. (2017) · Revista de Psicopatología y Psicología Clínica · doi:10.5944/rppc.vol.22.num.3.2017.18122 · Cited by 23 · see citing works
Psychometric properties of the mini-social phobia inventory (Mini-SPIN) in a large online treatment-seeking sample
Fogliati, V. J., Terides, M. D., Gandy, M., Staples, L., Johnston, L., Karin, E., Rapee, R. M., Titov, N., & Dear, B. F. (2016) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2016.1158206 · Cited by 23 · see citing works
Transdiagnostic internet-delivered cognitive-behaviour therapy (CBT) for adults with functional gastrointestinal disorders (FGID): A feasibility open trial
Dear, B. F., Fogliati, V. J., Fogliati, R., Gandy, M., McDonald, S., Talley, N. J., Holtmann, G., Titov, N., & Jones, M. (2018) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2018.02.015 · Cited by 23 · see citing works
Insights into internet-delivered cognitive behavioural therapy for public safety personnel: Exploration of client experiences during and after treatment
Beahm, J. D., McCall, H. C., Carleton, R. N., Titov, N., Dear, B., & Hadjistavropoulos, H. D. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100481 · Cited by 23 · see citing works
Guided versus self-guided internet delivered cognitive behavioural therapy for diagnosed anxiety and related disorders: a preliminary meta-analysis
Oey, L. T., McDonald, S., McGrath, L., Dear, B. F., & Wootton, B. M. (2023) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2023.2250073 · Cited by 22 · see citing works
Guided and unguided internet-delivered psychodynamic therapy for social anxiety disorder: A randomized controlled trial
Mechler, J., Lindqvist, K., Magnusson, K., Ringström, A., Krafman, J. D., Alvinzi, P., Kassius, L., Sowa, J., Andersson, G., & Carlbring, P. (2024) · npj Mental Health Research · doi:10.1038/s44184-024-00063-0 · Cited by 20 · see citing works
A Comparison of Self-Referral and Referral via Primary Care Providers, through Two Similar Digital Mental Health Services in Western Australia
Staples, L., Webb, N., Asrianti, L., Cross, S. P. M., Rock, D. J., Kayrouz, R., Karin, E., Dear, B. F., Nielssen, O. B., & Titov, N. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19020905 · Cited by 20 · see citing works
Internet-Delivered Psychological Treatment Options for Panic Disorder: A Review on Their Efficacy and Acceptability
Apolinário-Hagen, J. (2018) · Psychiatry Investigation · doi:10.30773/pi.2018.06.26 · Cited by 20 · see citing works
Brief online motivational interviewing pre-treatment intervention for enhancing internet-delivered cognitive behaviour therapy: A randomized controlled trial
Soucy, J. N., Hadjistavropoulos, H. D., Karin, E., Dear, B. F., & Titov, N. (2021) · Internet Interventions · doi:10.1016/j.invent.2021.100394 · Cited by 17 · see citing works
Transdiagnostic-focused apps for depression and anxiety: a meta-analysis
Linardon, J., Anderson, C., Messer, M., Liu, C., & Torous, J. B. (2025) · npj Digital Medicine · doi:10.1038/s41746-025-01860-3 · Cited by 18 · see citing works
Internet-delivered cognitive behavioural therapy for symptoms of PTSD among public safety personnel: Initial outcomes of an open cohort preference trial of transdiagnostic and disorder-specific therapy
McCall, H. C., Dear, B. F., Landry, C. A., Beahm, J. D., Gregory, J., Titov, N., Carleton, R. N., & Hadjistavropoulos, H. D. (2023) · Internet Interventions · doi:10.1016/j.invent.2023.100656 · Cited by 18 · see citing works
Accessibility and Applicability of Currently Available e-Mental Health Programs for Depression for People With Poststroke Aphasia: Scoping Review
Clunne, S. J., Ryan, B., Hill, A. J., Brandenburg, C., & Kneebone, I. (2018) · Journal of Medical Internet Research · doi:10.2196/jmir.9864 · Cited by 16 · see citing works
Facilitating access to iCBT: a randomized controlled trial assessing a translated version of an empirically validated program using a minimally monitored delivery model
Robichaud, M., Talbot, F., Titov, N., Dear, B. F., Hadjistavropoulos, H. D., Hadjistavropoulos, T., & Jbilou, J. (2019) · Behavioural and Cognitive Psychotherapy · doi:10.1017/s135246581900047x · Cited by 13 · see citing works
Understanding and Addressing Occupational Stressors in Internet-Delivered Therapy for Public Safety Personnel: A Qualitative Analysis
Beahm, J. D., Landry, C. A., McCall, H. C., Carleton, R. N., & Hadjistavropoulos, H. D. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19084744 · Cited by 11 · see citing works
Following up internet-delivered cognitive behaviour therapy (CBT): A longitudinal qualitative investigation of clients' usage of CBT skills
Eilert, N., Timulak, L., Duffy, D., Earley, C., Enrique, A., Kennedy, P., McCormack, C., Palacios, J., Wogan, R., & Richards, D. (2022) · Clinical Psychology & Psychotherapy · doi:10.1002/cpp.2619 · Cited by 11 · see citing works
“Previous quantitative research has highlighted iCBT's potential for long-term clinical effects (Buntrock et al., 2016; Fogliati et al., 2016; Ruwaard et al., 2010); however, regarding posttherapeutic CBT skills usage as a possible mechanism of effect maintenance, both of the aforementioned studies…”
Background
Efficacy of a transdiagnostic guided internet-delivered intervention for emotional, trauma and stress-related disorders in Mexican population: study protocol for a randomized controlled trial
la Rosa-Gómez, A. D., Flores-Plata, L. A., Esquivel-Santoveña, E. E., Torija, C. S. T., Flores, R. G., Rodríguez, A. D., Arenas-Landgrave, P., Castellanos-Vargas, R. O., Ruiz, E. B., Silvestre-Ramírez, R., et al. (2022) · BMC Psychiatry · doi:10.1186/s12888-022-04132-6 · Cited by 12 · see citing works
Outcomes of transdiagnostic internet-delivered cognitive behavioural therapy tailored to public safety personnel: A longitudinal observational study
Hadjistavropoulos, H. D., McCall, H. C., Dear, B. F., Beahm, J. D., Carleton, R. N., & Titov, N. (2024) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2024.102861 · Cited by 10 · see citing works
Decision-making about uptake and engagement with digital mental health services: a qualitative exploration of service user perspectives
Fisher, A. C., Corrigan, E., Cross, S. P. M., Ryan, K., Staples, L., Tan, R. L., Titov, N., & Dear, B. F. (2023) · Clinical Psychologist · doi:10.1080/13284207.2023.2279657 · Cited by 9 · see citing works
Web-Based Interventions to Help Australian Adults Address Depression, Anxiety, Suicidal Ideation, and General Mental Well-being: Scoping Review
Skaczkowski, G., van der Kruk, S., Loxton, S., Hughes-Barton, D., Howell, C., Turnbull, D., Jensen, N., Smout, M., & Gunn, K. (2022) · JMIR Mental Health · doi:10.2196/31018 · Cited by 9 · see citing works
“A rapid review of the evidence for each of these programs’ evaluations is provided in Multimedia Appendix 4 [10,12,17,42-151].”
BackgroundInfluential
Decision-making about uptake and engagement among digital mental health service users: a qualitative exploration of therapist perspectives
Fisher, A. C., Corrigan, E., Cross, S. P. M., Ryan, K., Staples, L., Tan, R. L., Webb, N., Titov, N., & Dear, B. F. (2023) · Clinical Psychologist · doi:10.1080/13284207.2022.2163157 · Cited by 9 · see citing works
Evaluation of The Practitioner Online Referral and Treatment Service (PORTS): the first 18 months of a state-wide digital service for adults with anxiety, depression, or substance use problems
Titov, N., Rock, D. J., Bezuidenhout, G., Webb, N., Kayrouz, R., Nielssen, O. B., Williams, L., Purtell, C., Dear, B. F., & Staples, L. (2019) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2019.1666162 · Cited by 9 · see citing works
Facilitating the Dissemination of iCBT for the Treatment of Anxiety and Depression: A Feasibility Study
DaPonte, D., Talbot, F., Titov, N., Dear, B. F., Hadjistavropoulos, H. D., Hadjistavropoulos, T., & Jbilou, J. (2018) · Behaviour Change · doi:10.1017/bec.2018.14 · Cited by 9 · see citing works
Web-Based Mindfulness Meditation as an Adjunct to Internet-Delivered Cognitive Behavioral Therapy for Public Safety Personnel: Mixed Methods Feasibility Evaluation Study
Landry, C. A., McCall, H. C., Beahm, J. D., Titov, N., Dear, B., Carleton, R. N., & Hadjistavropoulos, H. D. (2024) · JMIR Formative Research · doi:10.2196/54132 · Cited by 6 · see citing works
“More information on the origins of the intervention [25] and the adaptations of the intervention [29-32] can be found elsewhere.”
Background
Antidepressant medication use by patients accessing a national digital mental health service
Staples, L., Asrianti, L., Karin, E., Kayrouz, R., Cross, S. P. M., Bisby, M. A., Fisher, A. C., Dear, B. F., Titov, N., & Nielssen, O. B. (2022) · Journal of Affective Disorders · doi:10.1016/j.jad.2022.04.042 · Cited by 6 · see citing works
Digitale Gesundheitsanwendungen mit psychotherapeutischem Fokus
Guth, M., Wiebe, A., & Philipsen, A. (2023) · Der Nervenarzt · doi:10.1007/s00115-023-01446-y · Cited by 6 · see citing works
Predictors of outcome in self‐guided internet‐delivered cognitive‐behavior therapy for obsessive‐compulsive disorder: A preliminary investigation
Wootton, B. M., McDonald, S., Karin, E., Titov, N., & Dear, B. F. (2024) · Journal of Clinical Psychology · doi:10.1002/jclp.23710 · Cited by 6 · see citing works
Acceptability and effectiveness study of therapist-assisted internet-delivered cognitive behaviour therapy for agriculture producers
Beck, C. D., Peynenburg, V. A., Patterson, T., Titov, N., Dear, B. F., & Hadjistavropoulos, H. D. (2024) · Internet Interventions · doi:10.1016/j.invent.2024.100709 · Cited by 5 · see citing works
Terapia cognitivo-conductual transdiagnóstica en Atención Primaria: un contexto ideal
González‐Blanch, C., Ruiz-Torres, M., Cordero‐Andrés, P., Umaran‐Alfageme, O., Hernández-Abellán, A., Muñoz‐Navarro, R., & Vindel, A. C. (2018) · Revista de Psicoterapia · doi:10.33898/rdp.v29i110.243 · Cited by 4 · see citing works
Lessons learned from two feasibility trials of a translated and minimally monitored iCBT program for young adults among community and university samples
LeBlanc, J., Talbot, F., Fournier, V., Titov, N., & Dear, B. F. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100529 · Cited by 4 · see citing works
An Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Among Clients Referred and Funded by Insurance Companies Compared With Those Who Are Publicly Funded: Longitudinal Observational Study
Hadjistavropoulos, H. D., Peynenburg, V. A., Mehta, S., Adlam, K., Nugent, M., Gullickson, K. M., Titov, N., & Dear, B. F. (2019) · JMIR Mental Health · doi:10.2196/16005 · Cited by 4 · see citing works
Transdiagnostic cognitive behavioural therapy
Norton, P. J. (2022) · Clinical Psychologist · doi:10.1080/13284207.2022.2064212 · Cited by 4 · see citing works
Evaluation of an online-based self-help intervention for patients with panic disorder – Study protocol for a randomized controlled trial
Rubel, J. A., Quest, J., Pruessner, L., Timm, C., Hartmann, S. F., Barnow, S., Rittmeyer, L., Rosenbaum, D., & Lalk, C. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100584 · Cited by 4 · see citing works
Clinician guidance in digital therapeutics for panic disorder: Meta-analytic dissection and implications for regulatory framing and scalable deployment
Cho, I., Kim, B.-H., Lee, H., Song, Y., Chang, M. J., Kim, J., & Han, E. (2025) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2025.103074 · Cited by 3 · see citing works
Individually tailored internet-based cognitive behavioural therapy for adolescents, young adults and older adults with anxiety
Silfvernagel, K. (2017) · Linköping studies in behavioural science · doi:10.3384/diss.diva-135823 · Cited by 3 · see citing works
Indícios de eficácia dos tratamentos psicoterápicos pela internet: revisão sistemática1
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Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for generalized anxiety disorder and comorbid disorders: A randomized controlled trial
Dear, B. F., Staples, L. G., Terides, M. D., Karin, E., Zou, J., Johnston, L., Gandy, M., Fogliati, V. J., Wootton, B. M., McEvoy, P. M., et al. (2015) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2015.09.003 · Cited by 230 · see citing works
Transdiagnostic versus disorder-specific and clinician-guided versus self-guided internet-delivered treatment for social anxiety disorder and comorbid disorders: a randomized controlled trial
Dear, B. F., Staples, L. G., Terides, M. D., Fogliati, V. J., Sheehan, J., Johnston, L., Kayrouz, R., Dear, R., McEvoy, P. M., & Titov, N. (2016) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2016.05.004 · Cited by 114 · see citing works
Disorder-specific versus transdiagnostic and clinician-guided versus self-guided treatment for major depressive disorder and comorbid anxiety disorders: A randomized controlled trial
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A controlled trial of internet-based cognitive-behavioural therapy for panic disorder with face-to-face support from a general practitioner or email support from a psychologist.
Pier, C., Austin, D., Klein, B., Mitchell, J., Schattner, P. L., Ciechomski, L., Gilson, K., Pierce, D., Shandley, K. A., & Wade, V. (2008) · PubMed Central · Cited by 33 · see citing works

Authors: Fogliati, V. J., Dear, B. F., Staples, L. G., Terides, M. D., Sheehan, J., Johnston, L., Kayrouz, R., Dear, R., McEvoy, P. M., & Titov, N.
Affiliations: Macquarie University (AU)
Curtin University (AU)
Corresponding author: Dear, B.F.
ORCID: Fogliati, V.J.
Dear, B.F.
Staples, L.G.
Terides, M.D.
Kayrouz, R.
McEvoy, P.M.
Titov, N.
Venue: Journal of Anxiety Disorders
Publisher: Elsevier BV
Published: 2016-04
Volume: 39
Pages: 88-102
ISSN: 0887-6185 (ISSN-L)
DOI: 10.1016/j.janxdis.2016.03.005
OpenAlex: W2298366945
Cited by: 86
References: 83
Citations by year: 2026: 2 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 9 · 2021: 13 · 2020: 2 · 2019: 14 · 2018: 11 · 2017: 6 · 2016: 6 · 2015: 2
FWCI: 18.95
Type: journal article
Language: en
Open access: hybrid
doi.org
Licence: cc-by-nc-nd
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
creativecommons.org/licenses/by-nc-nd/4.0/ (vor)
Locations: Journal of Anxiety Disorders (publishedVersion, cc-by-nc-nd)
PubMed (publishedVersion)
eSpace (Curtin University) (submittedVersion, cc-by-nc-nd)
Funders: Australian National Health and Medical Research Council
NHMRC Australian Public Health Fellowship
Topics: Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: internet-delivered treatment, self-guided treatment, panic disorder, comorbid depression, generalized anxiety disorder, social anxiety disorder, treatment acceptability, treatment efficacy
MeSH terms: Phobia, Social, Adult, Anxiety Disorders, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Therapy, Computer-Assisted, Comorbidity, Cognitive Behavioral Therapy, Panic Disorder, Treatment Outcome, Internet, Stress Disorders, Traumatic, Acute

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Disorder-specific versus transdiagnostic and clinician-guided versus self-guided internet-delivered treatment for panic disorder and comorbid disorders: a randomized controlled trial

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