The gut microbiota as a mediator of metabolic benefits after bariatric surgery
Abstract
Bariatric surgery is based on major anatomic rearrangements in the gastrointestinal tract that coincide with functional and taxonomic changes in gut microbial communities. These alterations in gut anatomy and in the microbiota are associated with early resolution of obesity-related impairment of glycemic control and are marked weight loss in the long term. Moreover, altered bile acid metabolism has been implicated in the control of energy homeostasis, emerging as a pivotal orchestrator in the gut microbiota-mediated effects of bariatric surgery. In this review, we summarize the growing body of evidence linking changes in the gut microbiota to the metabolic benefits of bariatric surgery and discuss the potential mechanisms involved.
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Postsurgical increases in Proteobacteria and Verrucomicrobia (Akkermansia muciniphila) are often reported.
“On the other hand, postsurgical increase in the phyla Proteobacteria and Verrucomicrobia (Akkermansia muciniphila) are often reported [52, 53].”
From Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects (2020) · cites this paper as [53]
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Functional Foods and Lifestyle Approaches for Diabetes Prevention and Management
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Bariatric surgery: remission of inflammation, cardiometabolic benefits, and common adverse effects
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- Authors
- Anhê, F. F., Varin, T. V., Schertzer, J. D., & Marette, A.
- Affiliations
- Institut universitaire de cardiologie et de pneumologie de Québec (CA)
- Université Laval (CA)
- McMaster University (CA)
- Corresponding author
- Marette, André
- Venue
- Canadian Journal of Diabetes
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 41
- Issue
- 4
- Pages
- 439-447
- ISSN
- 1499-2671 (ISSN-L)
- OpenAlex
- W2617406638
- Cited by
- 93
- References
- 116
- Citations by year
- 2026: 3 · 2025: 3 · 2024: 10 · 2023: 10 · 2022: 13 · 2021: 13 · 2020: 11 · 2019: 16 · 2018: 7 · 2017: 6
- FWCI
- 1.02
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Canadian Journal of Diabetes (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Surgery › Bariatric Surgery and Outcomes
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- bariatric surgery, gut microbiota, obesity, bile acid metabolism, glycemic control, weight loss, energy homeostasis, metabolic benefits
- MeSH terms
- Gastrointestinal Microbiome, Humans, Obesity, Gastrointestinal Tract, Bariatric Surgery
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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