Altered expression of long noncoding RNAs in patients with major depressive disorder

Exploratory Data Analysis

David, F. N., & Tukey, J. W. (1977) · Biometrics · doi:10.2307/2529486 · Cited by 12,707 · see citing works

Chromatin modifications and their function

Kouzarides, T. (2007) · Cell · doi:10.1016/j.cell.2007.02.005 · Cited by 10,883 · see citing works

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt, R. D., Bertin, A., & Jalfre, M. (1977) · PubMed · Cited by 3,275 · see citing works

DNA methylation landscapes: Provocative insights from epigenomics

Suzuki, M. M., & Bird, A. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2341 · Cited by 3,039 · see citing works

Small silencing RNAs: an expanding universe

Ghildiyal, M., & Zamore, P. D. (2009) · Nature Reviews Genetics · doi:10.1038/nrg2504 · Cited by 2,314 · see citing works

Exploratory Data Analysis

Bulmer, M. (1978) · Sociology · doi:10.1177/003803857801200331 · Cited by 1,438 · see citing works

Epigenetic regulation in psychiatric disorders

Tsankova, N., Renthal, W., Kumar, A., & Nestler, E. J. (2007) · Nature reviews. Neuroscience · doi:10.1038/nrn2132 · Cited by 1,400 · see citing works

On the classification of long non-coding RNAs

Ma, L., Bajić, V. B., & Zhang, Z. (2013) · RNA Biology · doi:10.4161/rna.24604 · Cited by 1,333 · see citing works

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression

David, D. J., Samuels, B. A., Rainer, Q., Wang, J.-W., Marsteller, D., Mendez, I., Drew, M., Craig, D. A., Guiard, B. P., Guilloux, J.-P., et al. (2009) · Neuron · doi:10.1016/j.neuron.2009.04.017 · Cited by 1,267 · see citing works

Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression

Prensner, J. R., Iyer, M. K., Balbin, O. A., Dhanasekaran, S. M., Cao, Q., Brenner, J. C., Laxman, B., Asangani, I. A., Grasso, C. S., Kominsky, H. D., et al. (2011) · Nature Biotechnology · doi:10.1038/nbt.1914 · Cited by 1,026 · see citing works

Antidepressant Actions of Histone Deacetylase Inhibitors

Covington, H. E., Maze, I., LaPlant, Q. C., Vialou, V. F., Ohnishi, Y. N., Berton, O., Fass, D. M., Renthal, W., Rush, A. J., Wu, E. Y., et al. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.1758-09.2009 · Cited by 624 · see citing works

Non-coding RNAs as direct and indirect modulators of epigenetic regulation

Peschansky, V. J., & Wahlestedt, C. (2013) · Epigenetics · doi:10.4161/epi.27473 · Cited by 516 · see citing works

Reliability and validity of Japanese version of the Mini‐International Neuropsychiatric Interview

Otsubo, T., Tanaka, K., Koda, R., Shinoda, J., SANO, N., Tanaka, S., AOYAMA, H., Mimura, M., & Kamijima, K. (2005) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2005.01408.x · Cited by 508 · see citing works

Ribosome Dysfunction Is an Early Event in Alzheimer's Disease

Ding, Q., Markesbery, W. R., Chen, Q., Li, F., & Keller, J. N. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.3040-05.2005 · Cited by 433 · see citing works

Ro Small Cytoplasmic Ribonucleoproteins Are a Subclass of La Ribonucleoproteins: Further Characterization of the Ro and La Small Ribonucleoproteins from Uninfected Mammalian Cells

Hendrick, J. P., Wolin, S. L., Rinke, J., Lerner, M. R., & STEITZ, J. A. (1981) · Molecular and Cellular Biology · doi:10.1128/mcb.1.12.1138 · Cited by 400 · see citing works

Epigenetic Status of Gdnf in the Ventral Striatum Determines Susceptibility and Adaptation to Daily Stressful Events

Uchida, S., Hara, K., Kobayashi, A., Otsuki, K., Yamagata, H., Hobara, T., Suzuki, T., Miyata, N., & Watanabe, Y. (2011) · Neuron · doi:10.1016/j.neuron.2010.12.023 · Cited by 398 · see citing works

The long non-coding RNA Gomafu is acutely regulated in response to neuronal activation and involved in schizophrenia-associated alternative splicing

Barry, G., Briggs, J. A., Vanichkina, D. P., Poth, E. M., Beveridge, N. J., Ratnu, V. S., Nayler, S. P., Nones, K., Hu, J., Bredy, T. W., et al. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.45 · Cited by 394 · see citing works

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

Maida, Y., Yasukawa, M., Furuuchi, M., Lassmann, T., Possemato, R., Okamoto, N., Kasim, V., Hayashizaki, Y., Hahn, W. C., & Masutomi, K. (2009) · Nature · doi:10.1038/nature08283 · Cited by 384 · see citing works

Chronic low dose corticosterone exposure decreased hippocampal cell proliferation, volume and induced anxiety and depression like behaviours in mice

Murray, F., Smith, D., & Hutson, P. H. (2008) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2008.01.014 · Cited by 334 · see citing works

Non-coding RNAs, epigenetics and complexity

Costa, F. F. (2007) · Gene · doi:10.1016/j.gene.2007.12.008 · Cited by 319 · see citing works

MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity

Issler, O., Haramati, S., Paul, E. D., Maeno, H., Navon, I., Zwang, R., Gil, S., Mayberg, H. S., Dunlop, B. W., Menke, A., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.05.042 · Cited by 318 · see citing works

Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae

Schmitt, M., & Clayton, D. A. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.12.7935-7941.1993 · Cited by 314 · see citing works

The interplay between inflammation, oxidative stress, DNA damage, DNA repair and mitochondrial dysfunction in depression

Czarny, P., Wigner, P., Galecki, P., & Sliwinski, T. (2018) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.036 · Cited by 310 · see citing works

Long noncoding RNAs in development and disease of the central nervous system

Ng, S., Lin, L., Soh, B.-S., & Stanton, L. W. (2013) · Trends in Genetics · doi:10.1016/j.tig.2013.03.002 · Cited by 308 · see citing works

miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment

Lopez, J. P., Lim, R., Cruceanu, C., Crapper, L., Fasano, C., Labonte, B., Maussion, G., Yang, J. P., Yerko, V., Vigneault, E., et al. (2014) · Nature Medicine · doi:10.1038/nm.3582 · Cited by 308 · see citing works

Regionally specific regulation of ERK MAP kinase in a model of antidepressant-sensitive chronic depression

Gourley, S. L., Wu, F. J., Kiraly, D. D., Ploski, J. E., Kedves, A. T., Duman, R. S., & Taylor, J. R. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.07.016 · Cited by 287 · see citing works

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m500526200 · Cited by 280 · see citing works

Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode

Belzeaux-R, R., Bergon, A., Jeanjean, V., Loriod, B., Formisano‐Tréziny, C., Verrier, L., Loundou, A., Baumstarck, K., Boyer, L., Gall, V., et al. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.112 · Cited by 222 · see citing works

Functional roles of non-coding Y RNAs

Kowalski, M. P., & Krude, T. (2015) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2015.07.003 · Cited by 217 · see citing works

HuR and GRSF1 modulate the nuclear export and mitochondrial localization of the lncRNA RMRPPreprint

Noh, J., Kim, K. M., Abdelmohsen, K., Yoon, J.-H., Panda, A., Munk, R., Kim, J., Curtis, J., Moad, C. A., Wohler, C., et al. (2016) · Genes & Development · doi:10.1101/gad.276022.115 · Cited by 213 · see citing works

MicroRNA dysregulation in schizophrenia

Beveridge, N. J., & Cairns, M. J. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.12.029 · Cited by 202 · see citing works

Nuclear RNase MRP is required for correct processing of pre-5.8S rRNA in Saccharomyces cerevisiae.

Schmitt, M. E., & Clayton, D. A. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.12.7935 · Cited by 200 · see citing works

Identification of MicroRNA-124-3p as a Putative Epigenetic Signature of Major Depressive Disorder

Roy, B., Dunbar, M., Shelton, R. C., & Dwivedi, Y. (2017) · Neuropsychopharmacology · doi:10.1038/npp.2016.175 · Cited by 199 · see citing works

Role of human noncoding RNAs in the control of tumorigenesis

Li, L., Feng, T., Lian, Y., Zhang, G., Garen, A., & Song, X. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906005106 · Cited by 185 · see citing works

Altered gene expression of histone deacetylases in mood disorder patients

Hobara, T., Uchida, S., Otsuki, K., Matsubara, T., Funato, H., Matsuo, K., Suetsugi, M., & Watanabe, Y. (2010) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2009.08.015 · Cited by 185 · see citing works

Noncoding RNAs in neurodegeneration

Salta, E., & De Strooper, B. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.90 · Cited by 183 · see citing works

Epigenetic mechanisms of major depression: Targeting neuronal plasticity

Uchida, S., Yamagata, H., Seki, T., & Watanabe, Y. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12621 · Cited by 181 · see citing works

Hippocampal MicroRNA-124 Enhances Chronic Stress Resilience in Mice

Higuchi, F., Uchida, S., Yamagata, H., Abe-Higuchi, N., Hobara, T., Hara, K., Kobayashi, A., Shintaku, T., Itoh, Y., Suzuki, T., et al. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.0319-16.2016 · Cited by 158 · see citing works

DCC Confers Susceptibility to Depression-like Behaviors in Humans and Mice and Is Regulated by miR-218

Torres-Berrío, A., Lopez, J. P., Bagot, R. C., Nouel, D., Dal Bo, G., Cuesta, S., Zhu, L., Manitt, C., Eng, C., Cooper, H. M., et al. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.08.017 · Cited by 153 · see citing works

Functions of Noncoding RNAs in Neural Development and Neurological Diseases

Bian, S., & Sun, T. (2011) · Molecular Neurobiology · doi:10.1007/s12035-011-8211-3 · Cited by 152 · see citing works

Integrating the roles of long and small non-coding RNA in brain function and disease

Barry, G. (2014) · Molecular Psychiatry · doi:10.1038/mp.2013.196 · Cited by 150 · see citing works

The lncRNA PCAT29 Inhibits Oncogenic Phenotypes in Prostate Cancer

Malik, R., Patel, L. R., Prensner, J. R., Shi, Y., Iyer, M. K., Subramaniyan, S., Carley, A., Niknafs, Y. S., Sahu, A., Han, S., et al. (2014) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-14-0257 · Cited by 133 · see citing works

Altered sirtuin deacetylase gene expression in patients with a mood disorder

Abe, N., Uchida, S., Otsuki, K., Hobara, T., Yamagata, H., Higuchi, F., Shibata, T., & Watanabe, Y. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.01.016 · Cited by 131 · see citing works

Long Noncoding RNA-Directed Epigenetic Regulation of Gene Expression Is Associated With Anxiety-like Behavior in Mice

Spadaro, P. A., Flavell, C. R., Widagdo, J., Ratnu, V. S., Troup, M., Ragan, C., Mattick, J. S., & Bredy, T. W. (2015) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.02.004 · Cited by 124 · see citing works

Microarray Profiling and Co-Expression Network Analysis of Circulating lncRNAs and mRNAs Associated with Major Depressive Disorder

Liu, Z., Li, X., Sun, N., Xu, Y. J., Meng, Y.-Q., Yang, C., Wang, Y., & Zhang, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0093388 · Cited by 121 · see citing works

Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processingPreprint

Goldfarb, K. C., & Cech, T. R. (2017) · Genes & Development · doi:10.1101/gad.286963.116 · Cited by 119 · see citing works

Altered HDAC5 and CREB mRNA expressions in the peripheral leukocytes of major depression

Iga, J.-I., Ueno, S.-I., Yamauchi, K., Numata, S., Kinouchi, S., Tayoshi-Shibuya, S., Song, H., & Ohmori, T. (2007) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2006.12.014 · Cited by 105 · see citing works

Discovery of blood transcriptomic markers for depression in animal models and pilot validation in subjects with early-onset major depression

PAJER, K. A., Andrus, B. M., Gardner, W. P., Lourie, A., Strange, B., Campo, J. V., Bridge, J. A., Blizinsky, K. D., Dennis, K., Vedell, P. T., et al. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.26 · Cited by 105 · see citing works

Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus

Kasahara, T., Takata, A., Kato, T., Kubota-Sakashita, M., Sawada, T., Kakita, A., Mizukami, H., Kaneda, D., Ozawa, K., & Kato, T. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.156 · Cited by 102 · see citing works

Impaired hippocampal spinogenesis and neurogenesis and altered affective behavior in mice lacking heat shock factor 1

Uchida, S., Hara, K., Kobayashi, A., Fujimoto, M., Otsuki, K., Yamagata, H., Hobara, T., Abe, N., Higuchi, F., Shibata, T., et al. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1016424108 · Cited by 97 · see citing works

Alterations of microRNA-124 expression in peripheral blood mononuclear cells in pre- and post-treatment patients with major depressive disorder

He, S., Liu, X., Jiang, K., Peng, D., Hong, W., Fang, Y., Qian, Y., Yu, S., & Li, H. (2016) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2016.03.015 · Cited by 94 · see citing works

Long non-coding RNA H19 contributes to apoptosis of hippocampal neurons by inhibiting let-7b in a rat model of temporal lobe epilepsy

Han, C., Ge, M., Liu, Y., Zhao, X., Wang, K., Chen, N., Hu, W., Zhang, J., Li, L., & Meng, F. (2018) · Cell Death and Disease · doi:10.1038/s41419-018-0496-y · Cited by 92 · see citing works

Small RNAs derived from lncRNA RNase MRP have gene-silencing activity relevant to human cartilage–hair hypoplasia

Rogler, L. E., Kosmyna, B., Moskowitz, D. M., Bebawee, R. S., Rahimzadeh, J., Kutchko, K. M., Laederach, A., Notarangelo, L. D., Giliani, S. C., Bouhassira, E. E., et al. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt427 · Cited by 88 · see citing works

Long Non-Coding RNA: Potential Diagnostic and Therapeutic Biomarker for Major Depressive Disorder

Cui, X., Sun, X., Niu, W., Kong, L., He, M., Zhong, A., Chen, S., Jiang, K., Zhang, L.-Y., & Cheng, Z. (2016) · Medical Science Monitor · doi:10.12659/msm.899372 · Cited by 82 · see citing works

Blood diagnostic biomarkers for major depressive disorder using multiplex DNA methylation profiles: discovery and validation

Numata, S., Ishii, K., Tajima, A., Iga, J.-I., Kinoshita, M., Watanabe, S., Umehara, H., Fuchikami, M., Okada, S., Boku, S., et al. (2015) · Epigenetics · doi:10.1080/15592294.2014.1003743 · Cited by 79 · see citing works

Human Y5 RNA specializes a Ro ribonucleoprotein for 5S ribosomal RNA quality controlPreprint

Hogg, J. R., & Collins, K. (2007) · Genes & Development · doi:10.1101/gad.1603907 · Cited by 77 · see citing works

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease

Kocerha, J., Dwivedi, Y., & Brennand, K. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.30 · Cited by 76 · see citing works

State-dependent changes in the expression of DNA methyltransferases in mood disorder patients

Higuchi, F., Uchida, S., Yamagata, H., Otsuki, K., Hobara, T., Abe, N., Shibata, T., & Watanabe, Y. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.04.008 · Cited by 72 · see citing works

Roles of RNase P and Its Subunits

Jarrous, N. (2017) · Trends in Genetics · doi:10.1016/j.tig.2017.06.006 · Cited by 72 · see citing works

Blood Transcriptomic Markers in Patients with Late-Onset Major Depressive Disorder

Miyata, S., Kurachi, M., Okano, Y., Sakurai, N., Kobayashi, A., Harada, K., Yamagata, H., Matsuo, K., Takahashi, K., Narita, K., et al. (2016) · PLoS ONE · doi:10.1371/journal.pone.0150262 · Cited by 71 · see citing works

What Can Mitochondrial DNA Analysis Tell Us About Mood Disorders?

Kasahara, T., & Kato, T. (2017) · Biological Psychiatry · doi:10.1016/j.biopsych.2017.09.010 · Cited by 69 · see citing works

Telomere shortening in leukocyte subpopulations in depression

Karabatsiakis, A., Kolassa, I., Kolassa, S., Rudolph, K. L., & Dietrich, D. E. (2014) · BMC Psychiatry · doi:10.1186/1471-244x-14-192 · Cited by 67 · see citing works

Down-Regulation of <i>SIRT1</i> Gene Expression in Major Depressive Disorder

Luo, X.-J., & Zhang, C. (2016) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2016.16040394 · Cited by 66 · see citing works

Dysfunction in Ribosomal Gene Expression in the Hypothalamus and Hippocampus following Chronic Social Defeat Stress in Male Mice as Revealed by RNA-Seq

Смагин, Д. А., Kovalenko, I. L., Galyamina, A. G., Олегович, Б. А., Orlov, Y. L., & Kudryavtseva, N. N. (2015) · Neural Plasticity · doi:10.1155/2016/3289187 · Cited by 65 · see citing works

RMRP mutations in cartilage‐hair hypoplasia

Hermanns, P., Tran, A. A., Munivez, E. M., Carter, S., Zabel, B., Lee, B., & Leroy, J. G. (2006) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.31331 · Cited by 64 · see citing works

Aberrant H3.3 dynamics in NAc promote vulnerability to depressive-like behavior

Lepack, A. E., Bagot, R. C., Peña, C. J., Loh, Y.-H. E., Farrelly, L. A., Lu, Y., Powell, S. K., Lorsch, Z. S., Issler, O., Cates, H. M., et al. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1608270113 · Cited by 63 · see citing works

MALAT1 lncRNA Induces Autophagy and Protects Brain Microvascular Endothelial Cells Against Oxygen–Glucose Deprivation by Binding to miR-200c-3p and Upregulating SIRT1 Expression

Wang, S., Han, X., Mao, Z., Xin, Y., Maharjan, S., & Zhang, B. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.11.024 · Cited by 59 · see citing works

State-dependent changes in the expression of DNA methyltransferases in mood disorder patients

Higuchi, F. (2013) · Medical Entomology and Zoology · Cited by 57 · see citing works

PCAT-1: A Novel Oncogenic Long Non-Coding RNA in Human Cancers

Xiong, T., Li, J., Chen, F., & Zhang, F. (2019) · International Journal of Biological Sciences · doi:10.7150/ijbs.30970 · Cited by 56 · see citing works

Parkinson's Disease DJ-1 L166P Alters rRNA Biogenesis by Exclusion of TTRAP from the Nucleolus and Sequestration into Cytoplasmic Aggregates via TRAF6

Vilotti, S., Codrich, M., Ferro, M. D., Pinto, M., Ferrer, I., Collavin, L., Gustincich, S., & Zucchelli, S. (2012) · PLoS ONE · doi:10.1371/journal.pone.0035051 · Cited by 51 · see citing works

The emerging roles of MicroRNAs in autism spectrum disorders

Fregeac, J., Colleaux, L., & Nguyen, L. S. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.10.018 · Cited by 51 · see citing works

Why YRNAs? About Versatile RNAs and Their Functions

Köhn, M., Pazaitis, N., & Hüttelmaier, S. (2013) · Biomolecules · doi:10.3390/biom3010143 · Cited by 47 · see citing works

Intergenic variants may predispose to major depression disorder through regulation of long non-coding RNA expression

Ye, N., Rao, S., Du, T., Hu, H., Liu, Z., Shen, Y., & Xu, Q. (2016) · Gene · doi:10.1016/j.gene.2016.11.041 · Cited by 44 · see citing works

GAS5 silencing protects against hypoxia/ischemia-induced neonatal brain injury

Zhao, R., Zhu, L.-H., Shu, J., Qiao, L., & Xia, Z. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.02.070 · Cited by 43 · see citing works

Translational Identification of Transcriptional Signatures of Major Depression and Antidepressant Response

Hervé, M., Bergon, A., Guisquet, A. L., Leman, S., Consoloni, J.-L., Fernandez, N., Lefebvre, M., El‐Hage, W., Belzeaux-R, R., Belzung, C., et al. (2017) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2017.00248 · Cited by 40 · see citing works

MicroRNAs in Major Depressive Disorder

Fries, G. R., Zhang, W., Benevenuto, D., & Quevedo, J. (2019) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-05542-4_9 · Cited by 31 · see citing works

Identification of commonly altered genes between in major depressive disorder and a mouse model of depression

Yamagata, H., Uchida, S., Matsuo, K., Harada, K., Kobayashi, A., Nakashima, M., Nakano, M., Otsuki, K., Abe-Higuchi, N., Higuchi, F., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-03291-x · Cited by 27 · see citing works

Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert−/− mice

Zhou, Q.-G., Wu, H.-Y., Zhou, H., Liu, M.-Y., Lee, H. W., Liu, X., Devkota, S., Ro, E., Zhu, D.-Y., & Suh, H. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.106 · Cited by 25 · see citing works

Defects in lymphocyte telomere homeostasis contribute to cellular immune phenotype in patients with cartilage-hair hypoplasia

Aubert, G., Strauss, K. A., Lansdorp, P. M., & Rider, N. L. (2017) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2016.11.051 · Cited by 20 · see citing works

Distinct Expression Pattern of Epigenetic Machinery Genes in Blood Leucocytes and Brain Cortex of Depressive Patients

Rey, R., Chauvet‐Gélinier, J., Suaud‐Chagny, M., Ragot, S., Bonin, B., d’Amato, T., & Teyssier, J. (2018) · Molecular Neurobiology · doi:10.1007/s12035-018-1406-0 · Cited by 20 · see citing works

Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential

Yuan, M., Yang, B., Rothschild, G., Mann, J. J., Sanford, L. D., Tang, X., Huang, C., Wang, C., & Zhang, W. (2023) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-023-01519-z · Cited by 246 · see citing works

Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression

Issler, O., van der Zee, Y. Y., Ramakrishnan, A., Wang, J., Tan, C., Loh, Y.-H. E., Purushothaman, I., Walker, D. M., Lorsch, Z. S., Hamilton, P. J., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.03.023 · Cited by 156 · see citing works

Ginsenoside Rg1 Reduced Microglial Activation and Mitochondrial Dysfunction to Alleviate Depression-Like Behaviour Via the GAS5/EZH2/SOCS3/NRF2 Axis

Li, J., Gao, W. F., Zhao, Z., Li, Y., Yang, L., Wei, W., Ren, F., Yang, L., Yu, Y., Duan, W., et al. (2022) · Molecular Neurobiology · doi:10.1007/s12035-022-02740-7 · Cited by 83 · see citing works

Nutrition, Epigenetics, and Major Depressive Disorder: Understanding the Connection

Ortega, M. A., Fraile‐Μartinez, O., Montero, C. G., Álvarez-Mon, M. Á., Lahera, G., Monserrat, J., Llavero-Valero, M., Mora, F., Rodríguez–Jiménez, R., Fernández-Rojo, S., et al. (2022) · Frontiers in Nutrition · doi:10.3389/fnut.2022.867150 · Cited by 57 · see citing works

Emerging roles of long non-coding RNA in depression

Hao, W.-Z., Chen, Q., Wang, L., Tao, G., Gan, H., Deng, L.-J., Huang, J.-Q., & Chen, J.-X. (2022) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2022.110515 · Cited by 37 · see citing works

lncRNA MIR155HG Alleviates Depression-Like Behaviors in Mice by Regulating the miR-155/BDNF Axis

Zhang, H., Mei, Z., Huang, N., Ma, X., Yaping, W., Liu, L., Wang, L., Kejin, Z., & Liu, Y. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03234-z · Cited by 35 · see citing works

Long Non-coding RNA RMRP in the Pathogenesis of Human Disorders

Hussen, B. M., Azimi, T., Hidayat, H. J., Taheri, M. N., & Ghafouri‐Fard, S. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.676588 · Cited by 34 · see citing works

Downregulation of lncRNA GAS5 Alleviates Hippocampal Neuronal Damage in Mice with Depression-Like Behaviors Via Modulation of MicroRNA-26a/EGR1 Axis

Wu, Y., Wei, R., Jiang, Q. L., Wang, R., & Huang, H. (2020) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2020.105550 · Cited by 28 · see citing works

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Inserra, A., Campanale, A., Rezai, T., Romualdi, P., & Rubino, T. (2024) · Translational Psychiatry · doi:10.1038/s41398-024-03055-y · Cited by 27 · see citing works

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Zhang, Z., Wu, H., Peng, Q., Xie, Z., Chen, F., Ma, Y., Zhang, Y., Zhou, Y. C., Yang, J., Cheng Ann, C. H. E. N., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.730300 · Cited by 26 · see citing works

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Jovčevska, I., & Paska, A. V. (2021) · Neurochemistry International · doi:10.1016/j.neuint.2021.105140 · Cited by 25 · see citing works

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Kawatake-Kuno, A., Murai, T., & Uchida, S. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.708004 · Cited by 23 · see citing works

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Ceylan, D., Karaçiçek, B., Tufekci, K., Aksahin, I. C., Şenol, Ş. H., & Genç, Ş. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2023.1304660 · Cited by 24 · see citing works

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Xie, Y., Chen, L., Wang, L., Liu, T., Zheng, Y., Si, L., Ge, H., Xu, H., Xiao, L., & Wang, G. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-023-04727-x · Cited by 24 · see citing works

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Wang, L., Wang, J., Yang, Z., Wang, Y., Zhao, T., Luo, W., Liang, T., & Zheng, Y. (2023) · Aging · doi:10.18632/aging.205269 · Cited by 17 · see citing works

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Simchovitz, A., & Soreq, H. (2020) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2020.09.003 · Cited by 17 · see citing works

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Gibbons, A. S., Sundram, S., & Dean, B. (2020) · Non-Coding RNA · doi:10.3390/ncrna6030033 · Cited by 16 · see citing works

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Bu, T., Qiao, Z., Wang, W., Yang, X., Zhou, J., Chen, L., Yang, J., Xu, J., Yanping, J., Wang, Y., et al. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.651803 · Cited by 16 · see citing works

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Sargazi, S., Abghari, A. Z., Mirinejad, S., Nia, M. H., Majidpour, M., Danesh, H., Saravani, R., Sheervalilou, R., Shakiba, M., & Abghari, F. Z. (2022) · Nucleosides Nucleotides & Nucleic Acids · doi:10.1080/15257770.2022.2065017 · Cited by 14 · see citing works

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Denham, A. N., Drake, J., Gavrilov, M., Taylor, Z. N., Bacanu, S., & Vladimirov, V. I. (2022) · Non-Coding RNA · doi:10.3390/ncrna8040059 · Cited by 13 · see citing works

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Zhong, X.-L., Du, Y., Chen, L. T., & Cheng, Y. (2023) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2023.06.017 · Cited by 12 · see citing works

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Huang, Y., Jin, Y., Yao, S., Nan, G., & Mao, Y. Q. (2022) · Neurochemical Research · doi:10.1007/s11064-021-03508-6 · Cited by 10 · see citing works

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Sane, S., Ebrahimi, V., Shirvani-Farsani, Z., & Ghafouri‐Fard, S. (2024) · Journal of Molecular Neuroscience · doi:10.1007/s12031-024-02258-8 · Cited by 9 · see citing works

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Sires, A. M., Domínguez-Barragán, J., Lorenzón, N., Meskini, O., Buson, L., Silva, R. C., Bortolomasi, M., Perusi, G., Menesello, V., Gennarelli, M., et al. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106103 · Cited by 9 · see citing works

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Wang, S., Tang, L., Huang, N., & Wang, H. (2023) · Frontiers in Bioscience-Landmark · doi:10.31083/j.fbl2811321 · Cited by 8 · see citing works

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Sharifi, G., Eghtedarian, R., Taheri, M. N., Hussen, B. M., Eslami, S., Ghafouri‐Fard, S., & Sayad, A. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1031314 · Cited by 6 · see citing works

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Dwivedi, Y., & Roy, B. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03396-0 · Cited by 5 · see citing works

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Zhu, L., Guo, M., Li, K., Guo, C., & He, K. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252010995 · Cited by 5 · see citing works

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Zou, Z., Ye, Y., Zhou, B., & Zhang, Y. (2023) · World Journal of Psychiatry · doi:10.5498/wjp.v13.i2.36 · Cited by 5 · see citing works

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Shi, L., Han, X., Liu, F., Long, J., Jin, Y., Chen, S., Duan, G., & Yang, H. (2024) · Current Issues in Molecular Biology · doi:10.3390/cimb46070449 · Cited by 4 · see citing works

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Roy, B., Verma, A. K., Hulwi, E., & Dwivedi, Y. (2024) · Genomic psychiatry : · doi:10.61373/gp024i.0046 · Cited by 7 · see citing works

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Dini, N., Taheri, M. N., & Shirvani-Farsani, Z. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05974-y · Cited by 4 · see citing works

Helicid Alleviates Neuronal Apoptosis of Rats with Depression-Like Behaviors by Downregulating lncRNA-NONRATT030918.2

Zhang, Y., Jiang, Z.-Y., Wang, M., Zhang, X.-T., Ge, P., Wang, W., Zhang, Y., & Tong, J. (2024) · Molecular Neurobiology · doi:10.1007/s12035-024-04192-7 · Cited by 3 · see citing works

Long Noncoding RNA GAS5-Involved Progression of Neonatal Hydrocephalus and Inflammatory Responses

Zou, B., Zhang, Q., Gan, H. K., Qin, Y., Zhou, Y., Zhai, X., & Liang, P. (2024) · Molecular Biotechnology · doi:10.1007/s12033-024-01077-x · Cited by 2 · see citing works

Downregulated mitochondria-encoded long non-coding RNAs in mood disorders

Fettahoğlu, İ., Akşahin, İ. C., Yeşiloğlu, B., Çelik, H. E. A., Kaymakçı, E. Ç., Kendirlioglu, B. K., Frye, M. A., Özerdem, A., & Ceylan, D. (2025) · Journal of Affective Disorders · doi:10.1016/j.jad.2025.119653 · Cited by 1 · see citing works

Haplotype analysis of long-chain non-coding RNA NONHSAT102891 promoter polymorphisms and depression in Chinese individuals: A case-control association study

Li, Y., Wang, Y., Tang, X., Liang, P., Chen, J., Jiang, F. X., Yang, Q., & Liang, Y. (2023) · World Journal of Psychiatry · doi:10.5498/wjp.v13.i12.1005

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Jiang, H., Zhao, S., & Yang, G. (2024) · Research Square · doi:10.21203/rs.3.rs-4121013/v1

lncRNA TUG1 transcript levels and psychological disorders: insights into interplay of glycemic index and glycemic load

Rasaei, N., Esmaeili, F., Khadem, A., Yekaninejad, M. S., & Mirzaei, K. (2024) · BMC Medical Genomics · doi:10.1186/s12920-024-01976-7

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Wang, S., Zhao, Y. P., Pan, J., Zhang, D., Wang, A., & Ma, K. (2025) · Psychopharmacology · doi:10.1007/s00213-025-06978-6

Additional file 1 of The expression analysis of long noncoding RNAs PCAT-1, PCAT-29, and MER11C in bipolar disorder

Dini, N., Taheri, M., & Shirvani-Farsani, Z. (2024) · Figshare · doi:10.6084/m9.figshare.26752804

Additional file 2 of The expression analysis of long noncoding RNAs PCAT-1, PCAT-29, and MER11C in bipolar disorder

Dini, N., Taheri, M., & Shirvani-Farsani, Z. (2024) · Figshare · doi:10.6084/m9.figshare.26752807

Additional file 1 of Single-nucleus transcriptomic analysis reveals the relationship between gene expression in oligodendrocyte lineage and major depressive disorder

Xie, Y., Chen, L., Wang, L., Liu, T., Zheng, Y., Si, L., Ge, H., Xu, H., Xiao, L., & Wang, G. (2024) · Figshare · doi:10.6084/m9.figshare.26673627

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Li, S., Fu, Y., Wang, Z., Zhang, Y., Sun, T., & Miao, N. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27073099

Dysregulation of inflammation-related long non-coding RNAs in autistic children

Mohseni, M. M., Momeni, M., Shirvani-Farsani, Z., & Ghafouri‐Fard, S. (2026) · Biomarkers in Neuropsychiatry · doi:10.1016/j.bionps.2026.100138

The expressions and m6A methylation modification patterns of mRNAs and lncRNAs in major depressive disorder

Liu, L., Yang, Z., tan, K., Xu, S., Xu, J., Niu, J., & Yang, X. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2026.1850052

Long Non-Coding RNA: Potential Diagnostic and Therapeutic Biomarker for Major Depressive Disorder

Cui, X., Sun, X., Niu, W., Kong, L., He, M., Zhong, A., Chen, S., Jiang, K., Zhang, L.-Y., & Cheng, Z. (2016) · Medical Science Monitor · doi:10.12659/msm.899372 · Cited by 82 · see citing works

RNA high-throughput sequencing and clinical outcome validation indicate that long non-coding RNAs are biomarkers in the peripheral blood of patients with major depressive disorder

Zhang, G., Xu, D., Bu, S., Li, L., Jiao, J., Shi, Y., Xu, Y., Kong, Y., & Zhang, Z. (2025) · NeuroMarkers. · doi:10.1016/j.neumar.2025.100114 · Cited by 1 · see citing works

The link between long noncoding RNAs and depression

Huang, X., Luo, Y., Mao, Y.-S., & Jian-lin, J. (2016) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2016.06.004 · Cited by 92 · see citing works

LncRNA of peripheral blood mononuclear cells: HYMAI acts as a potential diagnostic and therapeutic biomarker for female major depressive disorder

Bu, T., Yang, J., Zhou, J., Liu, Y., Qiao, K., Wang, Y., Zhang, J., Zhao, E., Owura, B. K., Qiu, X., et al. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2025.1241089 · Cited by 1 · see citing works

Evaluating the Connection between MicroRNAs and Long Non-Coding RNAs for the Establishment of the Major Depressive Disorder Diagnosis

Prodan-Bărbulescu, C., Șeclăman, E. P., ENĂTESCU, V. R., Faur, F. I., Ghenciu, L. A., Tuţac, P., Pașca, P., & Grigoriță, L. O. (2024) · Biomedicines · doi:10.3390/biomedicines12030516 · Cited by 8 · see citing works