Stress-related factors in cannabis use and misuse: Implications for prevention and treatment
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We examined the role of stress as a risk factor and motivation for cannabis use/misuse. A systematic review of studies gathered from PsychINFO and MEDLINE databases was conducted. Findings suggest that cannabis is commonly used as a stress-coping strategy. Negative life events, trauma, and maladaptive coping were all related to consumption. Cannabis use for stress-coping purposes was most evident when examining chronic as compared with experimental use. Although many individuals may be able to use cannabis without consequences, there appears to be a subset of individuals who experience greater life stress and who may be more likely to use for stress-coping purposes. These individuals may be at greatest risk for addiction. Chronic use may potentiate stress-related motivation to use/abuse cannabis and is associated with decision-making deficits and alterations in brain-stress pathways that may exacerbate compulsive drug seeking and sensitize individuals to stress-related drug use. Overall, stress-coping interventions and harm reduction focused on reducing the amount ingested may facilitate prevention and recovery efforts.
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Stress is a significant factor in the maintenance of marijuana use.
“Stress has been shown to be a significant factor in the maintenance of marijuana use.”
From Effect of oxytocin on craving and stress response in marijuana-dependent individuals: A pilot study (2013) · cites this paper as Hyman and Sinha, 2009
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- Authors
- Hyman, S. M., & Sinha, R.
- Affiliations
- Yale University (US)
- Corresponding author
- Hyman, Scott M.
- ORCID
- Sinha, Rajita
- Venue
- Journal of Substance Abuse Treatment
- Publisher
- Elsevier BV
- Published
- 2009-06
- Volume
- 36
- Issue
- 4
- Pages
- 400-413
- ISSN
- 0740-5472 (ISSN-L)
- PMC
- PMC2696937
- OpenAlex
- W2080757251
- Cited by
- 344
- References
- 138
- Citations by year
- 2026: 24 · 2025: 35 · 2024: 20 · 2023: 29 · 2022: 24 · 2021: 32 · 2020: 43 · 2019: 30 · 2018: 15 · 2017: 14 · 2016: 13 · 2015: 13 · 2014: 19 · 2013: 10 · 2012: 6
- FWCI
- 0.57
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Substance Abuse Treatment (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (K02-DA17232, P50-DA16556)
- Topics
- Health Sciences › Medicine › Pharmacology › Cannabis and Cannabinoid Research
- Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
- Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
- Keywords
- cannabis use, cannabis use disorder, stress, stress coping, negative life events, trauma, maladaptive coping, chronic cannabis use, addiction risk, decision-making deficits, compulsive drug seeking, harm reduction, prevention, treatment
- MeSH terms
- Adaptation, Psychological, Marijuana Abuse, Decision Making, Humans, Risk Factors, Stress, Psychological, Databases, Factual, Behavior, Addictive, Harm Reduction
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