An update on laboratory detection and interpretation of antiphospholipid antibodies for diagnosis of antiphospholipid syndrome: guidance from the ISTH-SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS)

MIYAKIS, S., LOCKSHIN, M. D., ATSUMI, T., BRANCH, D. W., BREY, R. L., CERVERA, R., DERKSEN, R. H. W. M., DE GROOT, P. G., KOIKE, T., MERONI, P. L., et al. (2006) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2006.01753.x · Cited by 7,203 · see citing works

Clinical course of high‐risk patients diagnosed with antiphospholipid syndrome

PENGO, V., RUFFATTI, A., LEGNANI, C., GRESELE, P., BARCELLONA, D., ERBA, N., TESTA, S., MARONGIU, F., BISON, E., DENAS, G., et al. (2010) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2009.03674.x · Cited by 633 · see citing works

Lupus Anticoagulant IgG's (LA) Are Not Directed to Phospholipids only, but to a Complex of Lipid-Bound Human Prothrombin

Bevers, E. M., Galli, M., Barbui, T., Comfurius, P., & Zwaal, R. F. A. (1991) · Thrombosis and Haemostasis · doi:10.1055/s-0038-1646476 · Cited by 575 · see citing works

2023 ACR/EULAR antiphospholipid syndrome classification criteria

Barbhaiya, M., Zuily, S., Naden, R., Hendry, A., Manneville, F., Amigo, M.-C., Amoura, Z., Andrade, D., Andreoli, L., Artim-Esen, B., et al. (2023) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-224609 · Cited by 493 · see citing works

Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study

Pengo, V., Ruffatti, A., Legnani, C., Testa, S., Fierro, T., Marongiu, F., De Micheli, V., Gresele, P., Tonello, M., Ghirarduzzi, A., et al. (2011) · Blood · doi:10.1182/blood-2011-03-340232 · Cited by 465 · see citing works

Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis

Devreese, K. M. J., de Groot, P. G., de Laat, B., Erkan, D., Favaloro, E. J., Mackie, I., Martinuzzo, M., Ortel, T. L., Pengo, V., Rand, J. H., et al. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15047 · Cited by 439 · see citing works

Antiphospholipid syndrome

Schreiber, K. I., Sciascia, S., de Groot, P. G., Devreese, K. M. J., Jacobsen, S., Ruiz‐Irastorza, G., Salmon, J. E., Shoenfeld, Y., Shovman, O., & Hunt, B. J. (2018) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.103 · Cited by 437 · see citing works

Antiphospholipid antibodies and risk of myocardial infarction and ischaemic stroke in young women in the RATIO study: a case-control study

Urbanus, R. T., Siegerink, B., Roest, M., Rosendaal, F. R., de Groot, P. G., & Algra, A. (2009) · The Lancet Neurology · doi:10.1016/s1474-4422(09)70239-x · Cited by 429 · see citing works

The Second International Anti-Cardiolipin Standardization Workshop/The Kingston Anti-Phospholipid Antibody Study (KAPS) Group

Harris, E. N. (1990) · American Journal of Clinical Pathology · doi:10.1093/ajcp/94.4.476 · Cited by 416 · see citing works

Prediction of adverse pregnancy outcome by the presence of lupus anticoagulant, but not anticardiolipin antibody, in patients with antiphospholipid antibodies

Lockshin, M. D., Kim, M., Laskin, C. A., Guerra, M., Branch, D. W., Merrill, J., Petri, M., Porter, T. F., Sammaritano, L., Stephenson, M. D., et al. (2012) · Arthritis & Rheumatism · doi:10.1002/art.34402 · Cited by 388 · see citing works

IgG antibodies that recognize epitope Gly40-Arg43 in domain I of β2–glycoprotein I cause LAC, and their presence correlates strongly with thrombosis

de Laat, B., Derksen, R. H. W. M., Urbanus, R. T., & de Groot, P. G. (2005) · Blood · doi:10.1182/blood-2004-09-3387 · Cited by 378 · see citing works

Antibody profiles for the diagnosis of antiphospholipid syndrome

Biasiolo, A., Pegoraro, C., Cucchini, U., Noventa, F., Iliceto, S., & Pengo, V. (2005) · Thrombosis and Haemostasis · doi:10.1160/th04-12-0839 · Cited by 318 · see citing works

Laboratory criteria for antiphospholipid syndrome: communication from the SSC of the ISTH

Devreese, K. M. J., Ortel, T. L., Pengo, V., & de Laat, B. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13976 · Cited by 269 · see citing works

Anti-prothrombin (aPT) and anti-phosphatidylserine/prothrombin (aPS/PT) antibodies and the risk of thrombosis in the antiphospholipid syndrome

Sciascia, S., Sanna, G., Murru, V., Roccatello, D., Khamashta, M. A., & Bertolaccini, M. L. (2013) · Thrombosis and Haemostasis · doi:10.1160/th13-06-0509 · Cited by 253 · see citing works

Testing for Antiphospholipid antibodies with Solid Phase Assays: guidance from the SSC of the ISTH

Devreese, K. M. J., Pierangeli, S. S., de Laat, B., Tripodi, A., Atsumi, T., & Ortel, T. L. (2014) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12537 · Cited by 224 · see citing works

Pathogenic anti-β2-glycoprotein I antibodies recognize domain I of β2-glycoprotein I only after a conformational change

de Laat, B., Derksen, R. H. W. M., van Lummel, M., Pennings, M. T. T., & de Groot, P. G. (2005) · Blood · doi:10.1182/blood-2005-05-1943 · Cited by 208 · see citing works

Risk of venous and arterial thrombosis according to type of antiphospholipid antibodies in adults without systemic lupus erythematosus: a systematic review and meta-analysis

Reynaud, Q., Lega, J.-C., Mismetti, P., Chapelle, C., Wahl, D., Cathébras, P., & Laporte, S. (2014) · Autoimmunity Reviews · doi:10.1016/j.autrev.2013.11.004 · Cited by 179 · see citing works

Use of direct oral anticoagulants in patients with thrombotic antiphospholipid syndrome: Guidance from the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis

Zuily, S., Cohen, H., Isenberg, D. A., Woller, S. C., Crowther, M. A., Dufrost, V., Wahl, D. G., Doré, C. J., Cuker, A. C., Carrier, M., et al. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14935 · Cited by 156 · see citing works

Circulating Circular RNAs as Biomarkers for the Diagnosis and Prediction of Outcomes in Acute Ischemic Stroke

Zuo, L., Zhang, L., Zu, J., Wang, Z., Han, B., Chen, B., Cheng, M., Ju, M., Li, M., Shu, G., et al. (2019) · Stroke · doi:10.1161/strokeaha.119.027348 · Cited by 151 · see citing works

Lupus anticoagulant detection in anticoagulated patients. Guidance from the Scientific and Standardization Committee for lupus anticoagulant/antiphospholipid antibodies of the International Society on Thrombosis and Haemostasis

Tripodi, A., Cohen, H., & Devreese, K. M. J. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14846 · Cited by 143 · see citing works

IgG/IgM antiphospholipid antibodies present in the classification criteria for the antiphospholipid syndrome: a critical review of their association with thrombosis

Kelchtermans, H., Pelkmans, L., de Laat, B., & Devreese, K. M. J. (2016) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13379 · Cited by 131 · see citing works

Persistent Antiphospholipid Antibody (APL) in Asymptomatic Carriers as a Risk Factor for Future Thrombotic Events: A Nationwide Prospective Study

Mustonen, P., Lehtonen, K. V., Javela, K., & Puurunen, M. (2014) · Lupus · doi:10.1177/0961203314545410 · Cited by 127 · see citing works

Clinical accuracy for diagnosis of antiphospholipid syndrome in systemic lupus erythematosus: evaluation of 23 possible combinations of antiphospholipid antibody specificities

SCIASCIA, S., MURRU, V., SANNA, G., ROCCATELLO, D., KHAMASHTA, M. A., & BERTOLACCINI, M. L. (2012) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12014 · Cited by 116 · see citing works

Clinical Characterization of Antiphospholipid Syndrome by Detection of IgG Antibodies Against β 2 ‐Glycoprotein I Domain 1 and Domain 4/5: Ratio of Anti–Domain 1 to Anti–Domain 4/5 As a Useful New Biomarker for Antiphospholipid Syndrome

Andréoli, L., Chighizola, C. B., Nalli, C., Gerosa, M., Borghi, M. O., Pregnolato, F., Grossi, C., Zanola, A., Allegri, F., Norman, G. L., et al. (2015) · Arthritis & Rheumatology · doi:10.1002/art.39187 · Cited by 105 · see citing works

Immune responses against domain I of β2-glycoprotein I are driven by conformational changes: Domain I of β2-glycoprotein I harbors a cryptic immunogenic epitope

de Laat, B., van Berkel, M., Urbanus, R. T., Siregar, B., de Groot, P. G., Gebbink, M. F. B. G., & Maas, C. (2011) · Arthritis & Rheumatism · doi:10.1002/art.30633 · Cited by 103 · see citing works

Confirmation of initial antiphospholipid antibody positivity depends on the antiphospholipid antibody profile

Pengo, V., Ruffatti, A., Del Ross, T., Tonello, M., Cuffaro, S., Hoxha, A., Banzato, A., Bison, E., Denas, G., Bracco, A., et al. (2013) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.12264 · Cited by 101 · see citing works

Survey of lupus anticoagulant diagnosis by central evaluation of positive plasma samples

Pengo, V., Biasiolo, A., Gresele, P., Marongiu, F., Erba, N., Veschi, F., Ghirarduzzi, A., Candia, E. D., Montaruli, B., Testa, S., et al. (2007) · Journal of Thrombosis and Haemostasis · doi:10.1111/j.1538-7836.2007.02454.x · Cited by 95 · see citing works

Thrombotic risk assessment in the antiphospholipid syndrome requires more than the quantification of lupus anticoagulants

Devreese, K., Peerlinck, K., & Hoylaerts, M. F. (2010) · Blood · doi:10.1182/blood-2009-09-244426 · Cited by 93 · see citing works

The (non-)sense of detecting anti-cardiolipin and anti-β2glycoprotein I IgM antibodies in the antiphospholipid syndrome

Chayoua, W., Kelchtermans, H., Gris, J., Moore, G. W., Musiał, J., Wahl, D., de Groot, P. G., de Laat, B., & Devreese, K. M. J. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14633 · Cited by 89 · see citing works

Trial of Rivaroxaban in AntiPhospholipid Syndrome (TRAPS): Two‐year outcomes after the study closure

Pengo, V., Hoxha, A., Andréoli, L., Tincani, A., Silvestri, E., Prisco, D., Fierro, T., Gresele, P., Cafolla, A., Micheli, V. D., et al. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15158 · Cited by 79 · see citing works

Role of anti‐domain 1‐β2glycoprotein I antibodies in the diagnosis and risk stratification of antiphospholipid syndrome

Craemer, A. S. D., Musiał, J., & Devreese, K. M. J. (2016) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13389 · Cited by 78 · see citing works

Antiphospholipid antibody ELISAs: Survey on the performance of clinical laboratories assessed by using lyophilized affinity-purified IgG with anticardiolipin and anti-β2-Glycoprotein I activity

Pengo, V., Biasiolo, A., Bison, E., Chantarangkul, V., & Tripodi, A. (2006) · Thrombosis Research · doi:10.1016/j.thromres.2006.07.014 · Cited by 77 · see citing works

EUREKA algorithm predicts obstetric risk and response to treatment in women with different subsets of anti-phospholipid antibodies

Pregnolato, F., Gerosa, M., Raimondo, M. G., Comerio, C., Bartoli, F., Lonati, P. A., Borghi, M. O., Acaia, B., Ossola, M. W., Ferrazzi, E. M., et al. (2020) · Rheumatology · doi:10.1093/rheumatology/keaa203 · Cited by 76 · see citing works

Laboratory Diagnosis of Antiphospholipid Syndrome: Insights and Hindrances

Vandevelde, A., & Devreese, K. M. J. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11082164 · Cited by 76 · see citing works

Examining the prevalence of non-criteria anti-phospholipid antibodies in patients with anti-phospholipid syndrome: a systematic review

Rodriguez-Garcia, V., Ioannou, Y., Fernández‐Nebro, A., Isenberg, D. A., & Giles, I. (2015) · Rheumatology · doi:10.1093/rheumatology/kev226 · Cited by 75 · see citing works

Beyond thrombosis: Anti-β2GPI domain 1 antibodies identify late pregnancy morbidity in anti-phospholipid syndrome

Chighizola, C. B., Pregnolato, F., Andréoli, L., Bodio, C., Cesana, L., Comerio, C., Gerosa, M., Grossi, C., Kumar, R., Lazzaroni, M. G., et al. (2018) · Journal of Autoimmunity · doi:10.1016/j.jaut.2018.02.002 · Cited by 75 · see citing works

Persistent triple antiphospholipid antibody positivity as a strong risk factor of first thrombosis, in a long‐term follow‐up study of patients without history of thrombosis or obstetrical morbidity

Yelnik, C. M., Urbanski, G., Drumez, E., Sobanski, V, Maillard, H., Lanteri, A., Morell-Dubois, S., Caron, C., Dubucquoi, S., Launay, D., et al. (2017) · Lupus · doi:10.1177/0961203316657433 · Cited by 73 · see citing works

Increased mortality in patients with the lupus anticoagulant: the Vienna Lupus Anticoagulant and Thrombosis Study (LATS)

Gebhart, J., Posch, F., Koder, S., Perkmann, T., Quehenberger, P., Zoghlami, C., Ay, C., & Pabinger, I. (2015) · Blood · doi:10.1182/blood-2014-11-611129 · Cited by 72 · see citing works

Identification of high thrombotic risk triple‐positive antiphospholipid syndrome patients is dependent on anti‐cardiolipin and anti‐β2glycoprotein I antibody detection assays

Chayoua, W., Kelchtermans, H., Moore, G. W., Musiał, J., Wahl, D., de Laat, B., & Devreese, K. M. J. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14261 · Cited by 71 · see citing works

Prevalence of antibodies to prothrombin in solid phase (aPT) and to phosphatidylserine-prothrombin complex (aPS/PT) in patients with and without lupus anticoagulant

Sciascia, S., Murru, V., Garcia-Fernandez, C., Sanna, G., Khamashta, M., & Bertolaccini, M. L. (2013) · Thrombosis and Haemostasis · doi:10.1160/th12-07-0527 · Cited by 67 · see citing works

Semiquantitative interpretation of anticardiolipin and antiβ2glycoprotein I antibodies measured with various analytical platforms: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Vandevelde, A., Chayoua, W., de Laat, B., Gris, J., Moore, G. W., Musiał, J., Zuily, S., Wahl, D., & Devreese, K. M. J. (2022) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15585 · Cited by 66 · see citing works

Mixing studies in lupus anticoagulant testing are required at least in some type of samples

Devreese, K. M. J., & de Laat, B. (2015) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13020 · Cited by 63 · see citing works

A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E‐selectin on endothelial cells

Vega-Ostertag, M. E., Liu, X., Kwan‐Ki, H., Chen, P. P., & Pierangeli, S. S. (2006) · British Journal of Haematology · doi:10.1111/j.1365-2141.2006.06283.x · Cited by 62 · see citing works

Lupus anticoagulant testing during anticoagulation, including direct oral anticoagulants

Favaloro, E. J., & Pasalic, L. (2022) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12676 · Cited by 62 · see citing works

Antiphosphatidylserine/Prothrombin Antibodies: An Update on Their Association with Clinical Manifestations of Antiphospholipid Syndrome

Radin, M., Foddai, S. G., Cecchi, I., Rubini, E., Schreiber, K. I., Roccatello, D., Bertolaccini, M. L., & Sciascia, S. (2020) · Thrombosis and Haemostasis · doi:10.1055/s-0040-1705115 · Cited by 58 · see citing works

Antiphospholipid antibodies and the risk of thrombocytopenia in patients with systemic lupus erythematosus: A systematic review and meta-analysis

Chock, Y. P. E., Moulinet, T., Dufrost, V., Erkan, D., Wahl, D. G., & Zuily, S. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.102395 · Cited by 57 · see citing works

Performance of two new, automated chemiluminescence assay panels for anticardiolipin and anti‐beta2‐glycoprotein I antibodies in the laboratory diagnosis of the antiphospholipid syndrome

Hoecke, F. V., Persijn, L., Decavele, A.-S. C., & Devreese, K. M. J. (2012) · International Journal of Laboratory Hematology · doi:10.1111/j.1751-553x.2012.01448.x · Cited by 56 · see citing works

New insight into antiphospholipid syndrome: antibodies to β2glycoprotein I-domain 5 fail to induce thrombi in rats

Durigutto, P., Grossi, C., Borghi, M. O., Macor, P., Pregnolato, F., Raschi, E., Myers, M. P., de Groot, P. G., Meroni, P. L., & Tedesco, F. (2018) · Haematologica · doi:10.3324/haematol.2018.198119 · Cited by 55 · see citing works

Brief report: changes in antiphospholipid antibody titers during pregnancy: effects on pregnancy outcomes

Yelnik, C. M., Porter, T. F., Branch, D. W., Laskin, C. A., Merrill, J. T., Guerra, M. M., Lockshin, M. D., Buyon, J. P., Petri, M., Sammaritano, L. R., et al. (2016) · Arthritis & Rheumatology · doi:10.1002/art.39668 · Cited by 54 · see citing works

Internal Quality Control and External Quality Assurance in Testing for Antiphospholipid Antibodies: Part I—Anticardiolipin and Anti-β2-Glycoprotein I Antibodies

Favaloro, E. J., Wheatland, L., Jovanovich, S., Roberts-Thomson, P. J., & Wong, R. C. W. (2012) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0032-1311990 · Cited by 51 · see citing works

Detection of Anti-Cardiolipin and Anti-β2glycoprotein I Antibodies Differs between Platforms without Influence on Association with Clinical Symptoms

Chayouâ, W., Kelchtermans, H., Moore, G. W., Gris, J., Musiał, J., Wahl, D. G., Zuily, S., Gianniello, F., Fontana, P., Remijn, J. A., et al. (2019) · Thrombosis and Haemostasis · doi:10.1055/s-0039-1679901 · Cited by 51 · see citing works

Added value of antiphosphatidylserine/prothrombin antibodies in the workup of thrombotic antiphospholipid syndrome: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Vandevelde, A., Chayouâ, W., de Laat, B., Moore, G. W., Musiał, J., Zuily, S., Wahl, D. G., & Devreese, K. M. J. (2022) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15785 · Cited by 50 · see citing works

Clinical and laboratory practice for lupus anticoagulant testing: an International Society of Thrombosis and Haemostasis Scientific and Standardization Committee survey

Cohen, H., Mackie, I. J., & Devreese, K. M. J. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14560 · Cited by 48 · see citing works

The effect of unfractionated heparin, enoxaparin and danaparoid on lupus anticoagulant testing. Can activated carbon eliminate false positive results?

De Kesel, P. M. M., & Devreese, K. M. J. (2020) · Research and Practice in Thrombosis and Haemostasis · doi:10.1002/rth2.12264 · Cited by 47 · see citing works

International Multicenter, Multiplatform Study to Validate Taipan Snake Venom Time as a Lupus Anticoagulant Screening Test with Ecarin Time as the Confirmatory Test: Communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Moore, G. W., Jones, P. O., Platton, S., Hussain, N., White, D., Thomas, W., Rigano, J., Pouplard, C., Gray, E., & Devreese, K. M. J. (2021) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15438 · Cited by 47 · see citing works

Role of antiphospholipid antibodies in the diagnosis of antiphospholipid syndrome

Devreese, K. M. J., Zuily, S., & Meroni, P. L. (2021) · Journal of Translational Autoimmunity · doi:10.1016/j.jtauto.2021.100134 · Cited by 47 · see citing works

Resolving DOAC interference on aPTT, PT, and lupus anticoagulant testing by the use of activated carbon

Frans, G., Meeus, P., & Bailleul, E. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14488 · Cited by 44 · see citing works

Clinical significance of anti-domain 1 β2-glycoprotein I antibodies in antiphospholipid syndrome

Iwaniec, T., Kaczor, M. P., Celińska‐Löwenhoff, M., Polański, S., & Musiał, J. (2017) · Thrombosis Research · doi:10.1016/j.thromres.2017.02.019 · Cited by 43 · see citing works

Clinical Management of Thrombotic Antiphospholipid Syndrome

Tumian, N. R., & Hunt, B. J. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11030735 · Cited by 43 · see citing works

Variability in Exposure of Epitope G40-R43 of Domain I in Commercial Anti-Beta2-Glycoprotein I IgG ELISAs

Pelkmans, L., Kelchtermans, H., de Groot, P. G., Zuily, S., Regnault, V., Wahl, D. G., Pengo, V., & de Laat, B. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071402 · Cited by 42 · see citing works

Direct Oral Anticoagulant Adsorption: Impact on Lupus Anticoagulant Testing—Review of the Literature and Evaluation on Spiked and Patient Samples

De Kesel, P. M., & Devreese, K. M. J. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14894 · Cited by 40 · see citing works

Prevalence of aPhosphatidylserine/prothrombin antibodies and association with antiphospholipid antibody profiles in patients with antiphospholipid syndrome: A systematic review and meta-analysis

Zhu, R., Cheng, C., Yang, Y., Denas, G., & Pengo, V. (2022) · Thrombosis Research · doi:10.1016/j.thromres.2022.04.021 · Cited by 40 · see citing works

Anti–Domain I β2-Glycoprotein I Antibodies and Activated Protein C Resistance Predict Thrombosis in Antiphospholipid Syndrome: TAC(I)T Study

Zuily, S., de Laat, B., Guillemin, F., Kelchtermans, H., Magy-Bertrand, N., Desmurs‐Clavel, H., Lambert, M., Poindron, V., de Maistre, E., Dufrost, V., et al. (2020) · The Journal of Applied Laboratory Medicine · doi:10.1093/jalm/jfaa072 · Cited by 38 · see citing works

Laboratory Diagnostics of Antiphospholipid Syndrome

Bison, E., Denas, G., Jose, S., Zoppellaro, G., Banzato, A., & Pengo, V. (2017) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0037-1601331 · Cited by 36 · see citing works

The clinical value of assays detecting antibodies against domain I of β2-glycoprotein I in the antiphospholipid syndrome

Yin, D., de Laat, B., Devreese, K. M. J., & Kelchtermans, H. (2018) · Autoimmunity Reviews · doi:10.1016/j.autrev.2018.06.011 · Cited by 36 · see citing works

Clinical Relevance of Isolated Lupus Anticoagulant Positivity in Patients with Thrombotic Antiphospholipid Syndrome

Yin, D., de Groot, P. G., Ninivaggi, M., Devreese, K. M. J., & de Laat, B. (2021) · Thrombosis and Haemostasis · doi:10.1055/a-1344-4271 · Cited by 36 · see citing works

A multicenter study to assess the reproducibility of antiphospholipid antibody results produced by an automated system

Devreese, K. M. J., Poncet, A., Lindhoff‐Last, E., Musiał, J., de Moerloose, P., & Fontana, P. (2016) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13560 · Cited by 35 · see citing works

Variability of cut‐off values for the detection of lupus anticoagulants: results of an international multicenter multiplatform study

Tripodi, A., Chantarangkul, V., Cini, M., Devreese, K., Dlott, J. S., Giacomello, R., Gray, E., Legnani, C., Martinuzzo, M. E., Pradella, P., et al. (2017) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.13678 · Cited by 35 · see citing works

Some Patients with Antiphospholipid Syndrome Express hitherto Undescribed Antibodies to Cardiolipin-binding Proteins

Rampazzo, P., Biasiolo, A., Garin, J., Rosato, A., Betterle, C., Ruffatti, A., & Pengo, V. (2001) · Thrombosis and Haemostasis · doi:10.1055/s-0037-1612904 · Cited by 34 · see citing works

Dilute Russell's viper venom time reagents in lupus anticoagulant testing: a well‐considered choice

Depreter, B., & Devreese, K. M. J. (2017) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2016-0245 · Cited by 34 · see citing works

Additional laboratory tests to improve on the diagnosis of antiphospholipid syndrome

Pengo, V. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14896 · Cited by 34 · see citing works

Immunoglobulin G (IgG) anticardiolipin antibodies and recurrent cardiovascular events. A systematic review and Bayesian meta-regression analysis

Pastori, D., Bucci, T., Triggiani, M., Ames, P. R. J., Parrotto, S., Violi, F., Pignatelli, P., & Farcomeni, A. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.03.005 · Cited by 33 · see citing works

A systematic review of the association between anti-β-2 glycoprotein I antibodies and APS manifestations

Jiang, D., Lim, W., Crowther, M. A., & Garcia, D. A. (2021) · Blood Advances · doi:10.1182/bloodadvances.2021005205 · Cited by 33 · see citing works

Clinical characteristics and prognosis of patients with antiphospholipid antibodies based on cluster analysis: an 8-year cohort study

Qi, W., Zhao, J., Huang, C., Jiang, N., Li, J., Wu, C., Zhang, S., Hu, C., Xu, D., Wang, Q., et al. (2022) · Arthritis Research & Therapy · doi:10.1186/s13075-022-02814-w · Cited by 32 · see citing works

Detection of anti‐domain I antibodies by chemiluminescence enables the identification of high‐risk antiphospholipid syndrome patients: A multicenter multiplatform study

Yin, D., Chayouâ, W., Kelchtermans, H., et al. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14682 · Cited by 31 · see citing works

Validation of a commercially available kit to detect anti-phosphatidylserine/prothrombin antibodies in a cohort of systemic lupus erythematosus patients

Sciascia, S., Sanna, G., Murru, V., Khamashta, M. A., & Bertolaccini, M. L. (2013) · Thrombosis Research · doi:10.1016/j.thromres.2013.12.001 · Cited by 30 · see citing works

Is There an Additional Value in Detecting Anticardiolipin and Anti-β2 glycoprotein I IgA Antibodies in the Antiphospholipid Syndrome?

Chayouâ, W., Yin, D., Kelchtermans, H., Moore, G. W., Gris, J., Musiał, J., Zuily, S., Cate, H. T., de Laat, B., & Devreese, K. M. J. (2020) · Thrombosis and Haemostasis · doi:10.1055/s-0040-1714653 · Cited by 30 · see citing works

Estimates of Within-Subject Biological Variation of Protein C, Antithrombin, Protein S Free, Protein S Activity, and Activated Protein C Resistance in Pregnant Women

Kristoffersen, A. H., Petersen, P. H., Røraas, T., & Sandberg, S. (2017) · Clinical Chemistry · doi:10.1373/clinchem.2016.265900 · Cited by 27 · see citing works

Extended persistence of antiphospholipid antibodies beyond the 12‐week time interval: association with baseline antiphospholipid antibodies titres

Devignes, J., Smaïl‐Tabbone, M., Hervé, A., Cagninacci, G., Devignes, M., Lecompte, T., Zuily, S., & Wahl, D. (2019) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.13094 · Cited by 27 · see citing works

Solid Phase Assays for Antiphospholipid Antibodies

Devreese, K. M. J. (2022) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0042-1744364 · Cited by 27 · see citing works

Noncriteria antiphospholipid antibodies in antiphospholipid syndrome

Devreese, K. M. J. (2024) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.14268 · Cited by 27 · see citing works

Analytical and clinical comparison of different immunoassay systems for the detection of antiphospholipid antibodies

Montaruli, B., Luna, E. D., Erroi, L., Marchese, C. A., Mengozzi, G., Napoli, P., Nicolò, C., Romito, A., Bertero, M., Sivera, P., et al. (2016) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.12466 · Cited by 25 · see citing works

Antiphospholipid Syndrome With Isolated Isotype M Anticardiolipin and/or Anti-B2GPI Antibody Is Associated With Stroke

Urbanski, G., Yelnik, C., Maillard, H., Launay, D., Dubucquoi, S., HACHULLA, E., Hatron, P., & Lambert, M. (2018) · Stroke · doi:10.1161/strokeaha.118.023021 · Cited by 22 · see citing works

Fluctuation of Anti–Domain 1 and Anti– β2‐Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies

Chighizola, C. B., Pregnolato, F., ANDRADE, D. C. O. D., Tektonidou, M. G., Pengo, V., Ruiz‐Irastorza, G., Belmont, M. H., Gerosa, M., Fortin, P. R., Branch, D. W., et al. (2023) · Arthritis & Rheumatology · doi:10.1002/art.42459 · Cited by 22 · see citing works

Toward harmonized interpretation of anticardiolipin and anti–β2-glycoprotein I antibody detection for diagnosis of antiphospholipid syndrome using defined level intervals and likelihood ratios: communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Vandevelde, A., Gris, J., Moore, G. W., Musiał, J., Zuily, S., Wahl, D. G., & Devreese, K. M. J. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2024.04.016 · Cited by 22 · see citing works

Single or triple positivity for antiphospholipid antibodies in “carriers” or symptomatic patients: Untangling the knot

Bertin, D., Camoin‐Jau, L., Veit, V., Resseguier, N., Lambert, M., Buffet Delmas, P., Heim, X., Mège, J., Morange, P., & Bardin, N. (2021) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15518 · Cited by 21 · see citing works

Application of the thrombin generation assay in patients with antiphospholipid syndrome: A systematic review of the literature

Gehlen, R., Vandevelde, A., de Laat, B., & Devreese, K. M. J. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1075121 · Cited by 21 · see citing works

Laboratory criteria for antiphospholipid syndrome: reply

Devreese, K. M. J., Ortel, T. L., Pengo, V., & de Laat, B. (2018) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14238 · Cited by 20 · see citing works

Anti‐phosphatidylserine prothrombin antibodies as a predictor of the lupus anticoagulant in an all‐comer population

Pham, M., Orsolini, G., Crowson, C. S., Snyder, M. R., Pruthi, R. K., & Moder, K. G. (2022) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15792 · Cited by 20 · see citing works

Classification Criteria for the Antiphospholipid Syndrome: Not the Same as Diagnostic Criteria for Antiphospholipid Syndrome

Favaloro, E. J., Pasalic, L., & Lippi, G. (2023) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0043-1776318 · Cited by 20 · see citing works

Added value of antiphosphatidylserine/prothrombin antibodies in the workup of obstetric antiphospholipid syndrome: communication from the ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Vandevelde, A., Gris, J., Moore, G. W., Musiał, J., Zuily, S., Wahl, D. G., & Devreese, K. M. J. (2023) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2023.04.001 · Cited by 19 · see citing works

Lupus anticoagulant assay cut‐offs vary between reagents even when derived from a common set of normal donor plasmas

Moore, G. W., & Kumano, O. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14669 · Cited by 18 · see citing works

Development of a certified reference material for anti-β2-glycoprotein I IgG – commutability studies

Monogioudi, E., Martos, G., Sheldon, J., et al. (2020) · Clinical Chemistry and Laboratory Medicine (CCLM) · doi:10.1515/cclm-2020-0995 · Cited by 18 · see citing works

Antiphospholipid Syndrome

National Institute of Neurological Disorders and Stroke (NINDS) (2019) · Definitions · doi:10.32388/865343 · Cited by 18 · see citing works

A Clinical Approach for Defining the Threshold between Low and Medium Anti-Cardiolipin Antibody Levels for QUANTA Flash Assays

Lakos, G., Bentow, C., & Mähler, M. (2016) · Antibodies · doi:10.3390/antib5020014 · Cited by 17 · see citing works

Deciphered coagulation profile to diagnose the antiphospholipid syndrome using artificial intelligence

Kremers, R., Wahl, D. G., Zuily, S., Ninivaggi, M., Chayouâ, W., Regnault, V., Musiał, J., de Groot, P. G., Devreese, K. M. J., & de Laat, B. (2021) · Thrombosis Research · doi:10.1016/j.thromres.2021.05.008 · Cited by 17 · see citing works

A multi‐laboratory assessment of lupus anticoagulant assays performed on the ACL TOP 50 family for harmonized testing in a large laboratory network

Favaloro, E. J., Mohammed, S., Vong, R., Chapman, K., Swanepoel, P., Kershaw, G. W., Cai, N., Just, S., Connelly, L., Brighton, T., et al. (2022) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.13818 · Cited by 17 · see citing works

Additional laboratory tests to improve on the diagnosis of antiphospholipid syndrome: Response from Pengo

Pengo, V. (2020) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.15026 · Cited by 16 · see citing works

Close link between antiphosphatidylserine/prothrombin antibodies, lupus anticoagulant, and activated protein C resistance in tetra antiphospholipid antibody–positive subjects

Pontara, E., Bison, E., Cattini, M. G., Tonello, M., Denas, G., & Pengo, V. (2023) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2023.06.033 · Cited by 16 · see citing works

A Novel ELISA Assay for the Detection of Anti-Prothrombin Antibodies in Antiphospholipid Syndrome Patients at High Risk of Thrombosis

Chinnaraj, M., Pengo, V., & Pozzi, N. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.741589 · Cited by 15 · see citing works

Antiphosphatidylserine/prothrombin complex antibodies as a determinant of prothrombotic plasma fibrin clot properties in patients with antiphospholipid syndrome

Ząbczyk, M., Celińska‐Löwenhoff, M., Plens, K., Iwaniec, T., Musiał, J., & Undas, A. (2019) · Journal of Thrombosis and Haemostasis · doi:10.1111/jth.14551 · Cited by 14 · see citing works

A thrombin-driven neural net diagnoses the antiphospholipid syndrome without the need for interruption of anticoagulation

Kremers, R., Wahl, D. G., Zuily, S., Ninivaggi, M., Regnault, V., Musiał, J., de Groot, P. G., Devreese, K. M. J., & de Laat, B. (2024) · Blood Advances · doi:10.1182/bloodadvances.2023011938 · Cited by 12 · see citing works

Antiphosphatidylserine/prothrombin (aPS/PT) antibodies are associated with Raynaud phenomenon and migraine in primary thrombotic antiphospholipid syndrome

Kopytek, M., Natorska, J., & Undas, A. (2018) · Lupus · doi:10.1177/0961203317751644 · Cited by 11 · see citing works

Improvements in diagnosis and risk assessment of primary and secondary antiphospholipid syndrome

Petri, M. (2019) · Hematology · doi:10.1182/hematology.2019000046 · Cited by 11 · see citing works

Survey on antiphospholipid syndrome diagnosis and antithrombotic treatment in patients with ischemic stroke, other brain ischemic injury, or arterial thromboembolism in other sites: communication from ISTH SSC Subcommittee on Lupus Anticoagulant/Antiphospholipid Antibodies

Cohen, H., Werring, D. J., Chandratheva, A., Mittal, P., Devreese, K. M. J., Isenberg, D. A., Amoura, Z., ANDRADE, D. C. O. D., Baccouche, H., Baldwin, N., et al. (2023) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2023.06.020 · Cited by 11 · see citing works

Variable Performance of Lupus Anticoagulant Testing: The Australasian/Asia-Pacific Experience

Favaloro, E. J., Dean, E., & Arunachalam, S. (2024) · Seminars in Thrombosis and Hemostasis · doi:10.1055/s-0043-1776406 · Cited by 11 · see citing works

Fluctuation in the Levels of Immunoglobulin M and Immunoglobulin G Antibodies for Cardiolipin and β2-Glycoprotein among Healthy Pregnant Women

Al-Balushi, M. S., Hasson, S. S., Said, E. A., Al-Busaidi, J. Z., Al-Daihani, M. S., Othman, M. S., Sallam, T. A., Idris, M. A., Al-Kalbani, M., Woodhouse, N., et al. (2014) · Sultan Qaboos University medical journal · doi:10.18295/2075-0528.1622 · Cited by 10 · see citing works

Clinical and laboratory characteristics of isolated lupus anticoagulants

Mattia, E., Tonello, M., Ross, T. D., Zerbinati, P., Campello, E., Simioni, P., & Ruffatti, A. (2018) · Thrombosis Research · doi:10.1016/j.thromres.2018.03.008 · Cited by 10 · see citing works

Antiphospholipid antibody solid phase–based assays: problems and proposed solutions for the 2023 ACR/EULAR classification criteria for antiphospholipid syndrome

Huisman, A., Urbanus, R. T., & Meijer, P. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2023.12.019 · Cited by 10 · see citing works

Response to: Correspondence on ‘ACR/EULAR antiphospholipid syndrome classification criteria’ by Damoiseaux and van Beers

Barbhaiya, M., Zuily, S., Bertolaccini, M. L., et al. (2023) · Annals of the Rheumatic Diseases · doi:10.1136/ard-2023-225074 · Cited by 9 · see citing works

Lipid-binding antiphospholipid antibodies: significance for pathophysiology and diagnosis of the antiphospholipid syndrome

Müller-Calleja, N., Ruf, W., & Lackner, K. J. (2024) · Critical Reviews in Clinical Laboratory Sciences · doi:10.1080/10408363.2024.2305121 · Cited by 9 · see citing works

Cerebrovascular events in patients with isolated anti-phosphatidyl-serine/prothrombin antibodies

Radin, M., Barinotti, A., Foddai, S. G., Cecchi, I., Rubini, E., Roccatello, D., Menegatti, E., & Sciascia, S. (2021) · Immunologic Research · doi:10.1007/s12026-021-09208-1 · Cited by 7 · see citing works

An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment

Vilhena, J., Martins, M. R., Vicente, H., Grañeda, J. M., Caldeira, F., Gusmão, R., Neves, J., & Neves, J. (2017) · Journal of Medical Systems · doi:10.1007/s10916-017-0688-5 · Cited by 6 · see citing works

Anti-beta 2 glycoprotein I IgA in the SLICC classification criteria dataset

Elkhalifa, M., Orbai, A., Magder, L. S., et al. (2021) · Lupus · doi:10.1177/09612033211014248 · Cited by 6 · see citing works

Extra-criteria antiphospholipid antibodies in patients with small vessel brain lesions and clinical manifestations associated with antiphospholipid syndrome

Estévez, M. Á., Lanio, N., Molina, Á., Jiménez‐León, M. R., Picado, M. J., Esteban, E., Sánchez, S., Pallarés, L., & Juliá, M. R. (2023) · Journal of Stroke and Cerebrovascular Diseases · doi:10.1016/j.jstrokecerebrovasdis.2023.107034 · Cited by 6 · see citing works

Triple-positive antiphospholipid syndrome does not guarantee positivity in each lupus anticoagulant assay

Moore, G. W., Foxton, E., Platton, S., Yartey, N., White, D., & MacDonald, S. G. (2023) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2023.08.009 · Cited by 6 · see citing works

Laboratory Testing for Non-criteria Antiphospholipid Antibodies: Antibodies Toward the Domain I of Beta2-Glycoprotein I (aDI)

Devreese, K. M. J. (2023) · Methods in molecular biology · doi:10.1007/978-1-0716-3175-1_21 · Cited by 5 · see citing works

Taipan snake venom time has high sensitivity for lupus anticoagulants in non‐anticoagulated, triple positive antiphospholipid syndrome patients

Moore, G. W., Platton, S., Yartey, N., Foxton, E., White, D., & MacDonald, S. G. (2024) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.14240 · Cited by 5 · see citing works

Lupus Anticoagulant Testing in Challenging Situations: Navigating Complexities

Devreese, K. M. J. (2026) · International Journal of Laboratory Hematology · doi:10.1111/ijlh.14490 · Cited by 2 · see citing works

Standardization for Wood-based Panels in China

Dan-ping, W. (2008) · Mucai gongye

The Standardization of Rates

Fleiss, J. L., Levin, B. R., & Paik, M. C. (2003) · Wiley series in probability and statistics · doi:10.1002/0471445428.ch19 · Cited by 34 · see citing works

Better Facilities through Design Standardization.

Moore, W. B., & Cable, J. C. (1986)

Standardization Study for Advanced Aircraft Armament System Program

Graham, L. J., & SCHULZ, W. G. (1981) · Defense Technical Information Center (DTIC)

Study on Complex Standardization Mode and Typical Case

Fu, Y. (2013) · China Standardization