In synch but not in step: Circadian clock circuits regulating plasticity in daily rhythms

Development and Applications of CRISPR-Cas9 for Genome Engineering

Hsu, P. D., Lander, E. S., & Zhang, F. (2014) · Cell · doi:10.1016/j.cell.2014.05.010 · Cited by 5,762 · see citing works

Dynamical Systems in Neuroscience

Izhikevich, E. M. (2006) · The MIT Press eBooks · doi:10.7551/mitpress/2526.001.0001 · Cited by 3,776 · see citing works

CRISPR-Cas systems for editing, regulating and targeting genomes

Sander, J. D., & Joung, J. K. (2014) · Nature Biotechnology · doi:10.1038/nbt.2842 · Cited by 3,153 · see citing works

A circadian gene expression atlas in mammals: Implications for biology and medicine

Zhang, R., Lahens, N. F., Ballance, H. I., Hughes, M. E., & Hogenesch, J. B. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408886111 · Cited by 2,304 · see citing works

Coordinated Transcription of Key Pathways in the Mouse by the Circadian Clock

Panda, S., Antoch, M. P., Miller, B. H., Su, A. I., Schook, A. C., Straume, M., Schultz, P. G., Kay, S. A., Takahashi, J. S., & Hogenesch, J. B. (2002) · Cell · doi:10.1016/s0092-8674(02)00722-5 · Cited by 2,272 · see citing works

Central and Peripheral Circadian Clocks in Mammals

Mohawk, J. A., Green, C. B., & Takahashi, J. S. (2012) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-060909-153128 · Cited by 2,265 · see citing works

A functional analysis of circadian pacemakers in nocturnal rodents

Pittendrigh, C. S., & Daan, S. (1976) · Journal of Comparative Physiology A · doi:10.1007/bf01417856 · Cited by 2,129 · see citing works

Biological rhythms and the behavior of populations of coupled oscillators

Winfree, A. T. (1967) · Journal of Theoretical Biology · doi:10.1016/0022-5193(67)90051-3 · Cited by 2,035 · see citing works

Resetting central and peripheral circadian oscillators in transgenic rats

Yamazaki, S., Numano, R., Abe, M., Hida, A., Takahashi, R.-I., Ueda, M., Block, G. D., Sakaki, Y., Menaker, M., & Tei, H. (2000) · Science · doi:10.1126/science.288.5466.682 · Cited by 1,907 · see citing works

Suprachiasmatic nucleus : the mind's clock

Klein, D. C., Moore, R. Y., & Reppert, S. M. (1991) · Cited by 1,713 · see citing works

A functional analysis of circadian pacemakers in nocturnal rodents: V. Pacemaker structure: A clock for all seasons

Pittendrigh, C. S., & Daan, S. (1976) · Journal of Comparative Physiology ? A · doi:10.1007/bf01417860 · Cited by 1,636 · see citing works

Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms.

Welsh, D. K., Logothetis, D., Meister, M., & Reppert, S. (1995) · Neuron · doi:10.1016/0896-6273(95)90214-7 · Cited by 1,535 · see citing works

Sync: The Emerging Science of Spontaneous Order

Goldenfeld, N. D. (2004) · Physics Today · doi:10.1063/1.1784276 · Cited by 1,528 · see citing works

Extensive and divergent circadian gene expression in liver and heart

Storch, K.-F., Lipan, O., Leykin, I., Viswanathan, N., Davis, F. C., Wong, W. H., & Weitz, C. J. (2002) · Nature · doi:10.1038/nature744 · Cited by 1,509 · see citing works

Exogenous and Endogenous Components in Circadian RhythmsPreprint

Aschoff, J. (1960) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1960.025.01.004 · Cited by 1,487 · see citing works

The neurosciences. Third study program

(1975) · Comparative Biochemistry and Physiology Part A Physiology · doi:10.1016/s0300-9629(75)80111-3 · Cited by 1,445 · see citing works

Circadian Rhythms and the Circadian Organization of Living SystemsPreprint

Pittendrigh, C. S. (1960) · Cold Spring Harbor Symposia on Quantitative Biology · doi:10.1101/sqb.1960.025.01.015 · Cited by 1,397 · see citing works

Sync: The Emerging Science of Spontaneous Order

Strogatz, S. H. (2003) · Cited by 1,297 · see citing works

Melanopsin and rod-cone photoreceptive systems account for all major accessory visual functions in mice

Hattar, S., Lucas, R. J., Mrosovsky, N., Thompson, S., Douglas, R. H., Hankins, M. W., Lem, J., Biel, M., Hofmann, F., Foster, R. G., et al. (2003) · Nature · doi:10.1038/nature01761 · Cited by 1,245 · see citing works

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

Welsh, D. K., Takahashi, J. S., & Kay, S. A. (2010) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021909-135919 · Cited by 1,216 · see citing works

Circadian Gene Expression in Individual Fibroblasts

Nagoshi, E., Saini, C., Bauer, C. R., Laroche, T., Naef, F., & Schibler, U. (2004) · Cell · doi:10.1016/j.cell.2004.11.015 · Cited by 1,003 · see citing works

Gap junctions: New tools, new answers, new questions

Bennett, M. V. L., Barrio, L. C., Bargiello, T. A., Spray, D. C., Hertzberg, E. L., & Sáez, J. C. (1991) · Neuron · doi:10.1016/0896-6273(91)90241-q · Cited by 970 · see citing works

Synchronization of Cellular Clocks in the Suprachiasmatic Nucleus

Yamaguchi, S., Isejima, H., Matsuo, T., Okura, R., Yagita, K., Kobayashi, M., & Okamura, H. (2003) · Science · doi:10.1126/science.1089287 · Cited by 934 · see citing works

Three period Homologs in Mammals: Differential Light Responses in the Suprachiasmatic Circadian Clock and Oscillating Transcripts Outside of Brain

Zylka, M. J., Shearman, L. P., Weaver, D. R., & Reppert, S. M. (1998) · Neuron · doi:10.1016/s0896-6273(00)80492-4 · Cited by 865 · see citing works

Suprachiasmatic nucleus in the mouse: retinal innervation, intrinsic organization and efferent projections

Abrahamson, E. E., & Moore, R. Y. (2001) · Brain Research · doi:10.1016/s0006-8993(01)02890-6 · Cited by 788 · see citing works

The circadian visual system, 2005

Morin, L. P., & Allen, C. N. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.08.003 · Cited by 786 · see citing works

ELECTRICAL SYNAPSES IN THE MAMMALIAN BRAIN

Connors, B. W., & Long, M. A. (2004) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.041002.131128 · Cited by 784 · see citing works

Mammalian Photoperiodic System: Formal Properties and Neuroendocrine Mechanisms of Photoperiodic Time Measurement

Goldman, B. D. (2001) · Journal of Biological Rhythms · doi:10.1177/074873001129001980 · Cited by 771 · see citing works

A functional analysis of circadian pacemakers in nocturnal rodents

Pittendrigh, C. S., & Daan, S. (1976) · Journal of Comparative Physiology A · doi:10.1007/bf01417859 · Cited by 765 · see citing works

Vasoactive intestinal polypeptide mediates circadian rhythmicity and synchrony in mammalian clock neurons

Aton, S. J., Colwell, C. S., Harmar, A. J., Waschek, J. A., & Herzog, E. D. (2005) · Nature Neuroscience · doi:10.1038/nn1419 · Cited by 764 · see citing works

Circadian Rhythms in Man: A self-sustained oscillator with an inherent frequency underlies human 24-hour periodicity

Aschoff, J. (1965) · Science · doi:10.1126/science.148.3676.1427 · Cited by 752 · see citing works

Molecular components of the mammalian circadian clock

Buhr, E. D., & Takahashi, J. S. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25950-0_1 · Cited by 738 · see citing works

Bioluminescence imaging of individual fibroblasts reveals persistent, independently phased circadian rhythms of clock gene expression

Welsh, D. K., Yoo, S.-H., Liu, A. C., Takahashi, J. S., & Kay, S. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.11.057 · Cited by 726 · see citing works

Melanopsin is required for non-image-forming photic responses in blind mice

Panda, S., Provencio, I., Tu, D. C., Pires, S. S., Rollag, M. D., Castrucci, A. M., Pletcher, M. T., Sato, T. K., Wiltshire, T., Andahazy, M., et al. (2003) · Science · doi:10.1126/science.1086179 · Cited by 711 · see citing works

Circadian rhythms in isolated brain regions

Abe, M., Herzog, E. D., Yamazaki, S., Straume, M., Tei, H., Sakaki, Y., Menaker, M., & Block, G. D. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-01-00350.2002 · Cited by 681 · see citing works

The neurosciences-third study program

Hécaen, H. (1975) · Neuropsychologia · doi:10.1016/0028-3932(75)90080-9 · Cited by 635 · see citing works

Hypothalamic integration of central and peripheral clocks

Buijs, R. M., & Kalsbeek, A. (2001) · Nature reviews. Neuroscience · doi:10.1038/35081582 · Cited by 580 · see citing works

GABA is the principal neurotransmitter of the circadian system

Moore, R. Y., & Speh, J. C. (1993) · Neuroscience Letters · doi:10.1016/0304-3940(93)90120-a · Cited by 555 · see citing works

The VPAC2 Receptor Is Essential for Circadian Function in the Mouse Suprachiasmatic Nuclei

Harmar, A. J., Marston, H. M., Shen, S., Spratt, C., West, K. M., Sheward, W. J., Morrison, C. F., Dorin, J. R., Piggins, H. D., Reubi, J.-C., et al. (2002) · Cell · doi:10.1016/s0092-8674(02)00736-5 · Cited by 549 · see citing works

Suprachiasmatic nucleus organization

Moore, R. Y., Speh, J. C., & Leak, R. K. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0575-2 · Cited by 547 · see citing works

Strange vision: ganglion cells as circadian photoreceptors

Berson, D. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00130-9 · Cited by 546 · see citing works

Neurotransmitters of the hypothalamic suprachiasmatic nucleus: Immunocytochemical analysis of 25 neuronal antigens

van den Pol, A. N., & Tsujimoto, K. L. (1985) · Neuroscience · doi:10.1016/0306-4522(85)90254-4 · Cited by 534 · see citing works

Cellular Construction of a Circadian Clock: Period Determination in the Suprachiasmatic Nuclei

Liu, C., Weaver, D. R., Strogatz, S. H., & Reppert, S. M. (1997) · Cell · doi:10.1016/s0092-8674(00)80473-0 · Cited by 508 · see citing works

The Suprachiasmatic Nucleus: A 25-Year Retrospective

Weaver, D. R. (1998) · Journal of Biological Rhythms · doi:10.1177/074873098128999952 · Cited by 508 · see citing works

A Broad Role for Melanopsin in Nonvisual Photoreception

Gooley, J. J., Lü, J., Fischer, D., & Saper, C. B. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-18-07093.2003 · Cited by 476 · see citing works

Orchestrating time: arrangements of the brain circadian clock

Antle, M. C., & Silver, R. (2005) · Trends in Neurosciences · doi:10.1016/j.tins.2005.01.003 · Cited by 463 · see citing works

Clocks not winding down: unravelling circadian networks

Zhang, E. E., & Kay, S. A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2995 · Cited by 446 · see citing works

Biological Oscillators: their Mathematical Analysis

(1973) · Elsevier eBooks · doi:10.1016/b978-0-12-547350-7.x5001-9 · Cited by 445 · see citing works

Synchronization and Maintenance of Timekeeping in Suprachiasmatic Circadian Clock Cells by Neuropeptidergic Signaling

Maywood, E. S., Reddy, A. B., Wong, G. K. Y., O'Neill, J. S., O'Brien, J. A., McMahon, D. G., Harmar, A. J., Okamura, H., & Hastings, M. H. (2006) · Current Biology · doi:10.1016/j.cub.2006.02.023 · Cited by 438 · see citing works

The circadian visual system

Morin, L. P. (1994) · Brain Research Reviews · doi:10.1016/0165-0173(94)90005-1 · Cited by 437 · see citing works

Cell-Specific Expression of Connexins and Evidence of Restricted Gap Junctional Coupling between Glial Cells and between Neurons

Rash, J. E., Yasumura, T., Dudek, F. E., & Nagy, J. I. (2001) · Journal of Neuroscience · doi:10.1523/jneurosci.21-06-01983.2001 · Cited by 432 · see citing works

Constant light desynchronizes mammalian clock neurons

Ohta, H., Yamazaki, S., & McMahon, D. G. (2005) · Nature Neuroscience · doi:10.1038/nn1395 · Cited by 405 · see citing works

Disrupted circadian rhythms in VIP- and PHI-deficient mice

Colwell, C. S., Michel, S. H., Itri, J. N., Rodriguez, W. I., Nguyen‐Van‐Tam, J. S., Lelièvre, V., Hu, Z., Liu, X., & Waschek, J. A. (2003) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00200.2003 · Cited by 384 · see citing works

Vertebrate Circadian Systems

Aschoff, J., Daan, S., & Groos, G. A. (1982) · Proceedings in life sciences · doi:10.1007/978-3-642-68651-1 · Cited by 373 · see citing works

GABA Synchronizes Clock Cells within the Suprachiasmatic Circadian Clock

Liu, C., & Reppert, S. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)80876-4 · Cited by 340 · see citing works

Mice Genetically Deficient in Vasopressin V1a and V1b Receptors Are Resistant to Jet Lag

Yamaguchi, Y., Suzuki, T., Mizoro, Y., Kori, H., Okada, K., Chen, Y., Fustin, J., Yamazaki, F., Mizuguchi, N., Zhang, J., et al. (2013) · Science · doi:10.1126/science.1238599 · Cited by 334 · see citing works

A GABAergic Mechanism Is Necessary for Coupling Dissociable Ventral and Dorsal Regional Oscillators within the Circadian Clock

Albus, H., Vansteensel, M. J., Michel, S. H., Block, G. D., & Meijer, J. H. (2005) · Current Biology · doi:10.1016/j.cub.2005.03.051 · Cited by 328 · see citing works

Immunogold evidence that neuronal gap junctions in adult rat brain and spinal cord contain connexin-36 but not connexin-32 or connexin-43

Rash, J. E., Staines, W. A., Yasumura, T., Patel, D., Furman, C. S., Stelmack, G. L., & Nagy, J. I. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.13.7573 · Cited by 293 · see citing works

Clock genes in mammalian peripheral tissues

Balsalobre, A. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0585-0 · Cited by 288 · see citing works

Come Together, Right…Now: Synchronization of Rhythms in a Mammalian Circadian Clock

Aton, S. J., & Herzog, E. D. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.001 · Cited by 288 · see citing works

Antiphase Oscillation of the Left and Right Suprachiasmatic Nuclei

de la, H. O., Iglesia, Meyer, J. L., Carpino, A., & Schwartz, W. J. (2000) · Science · doi:10.1126/science.290.5492.799 · Cited by 286 · see citing works

A diversity of paracrine signals sustains molecular circadian cycling in suprachiasmatic nucleus circuits

Maywood, E. S., Chesham, J. E., O’Brien, J., & Hastings, M. H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1101767108 · Cited by 284 · see citing works

Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity

Inagaki, N., Honma, S., Ono, D., Tanahashi, Y., & Honma, K. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0607713104 · Cited by 274 · see citing works

An Abrupt Shift in the Day/Night Cycle Causes Desynchrony in the Mammalian Circadian Center

Nagano, M., Adachi, A. A., Nakahama, K., Nakamura, T., Tamada, M., Meyer-Bernstein, E. L., Sehgal, A., & Shigeyoshi, Y. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-14-06141.2003 · Cited by 273 · see citing works

Output pathways of the mammalian suprachiasmatic nucleus: coding circadian time by transmitter selection and specific targeting

Kalsbeek, A., & Buijs, R. M. (2002) · Cell and Tissue Research · doi:10.1007/s00441-002-0577-0 · Cited by 261 · see citing works

The Biological Clock Nucleus: A Multiphasic Oscillator Network Regulated by Light

Quintero, J. E., Kuhlman, S. J., & McMahon, D. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-22-08070.2003 · Cited by 259 · see citing works

The suprachiasmatic nuclei contain a tetrodotoxin-resistant circadian pacemaker.

Schwartz, W. J., Gross, R. A., & Morton, M. T. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.6.1694 · Cited by 258 · see citing works

Photic regulation of peptides located in the ventrolateral subdivision of the suprachiasmatic nucleus of the rat: daily variations of vasoactive intestinal polypeptide, gastrin-releasing peptide, and neuropeptide Y

Shinohara, K., Tominaga, K., Isobe, Y., & Inouye, S. T. (1993) · Journal of Neuroscience · doi:10.1523/jneurosci.13-02-00793.1993 · Cited by 257 · see citing works

Cellular Clocks in AVP Neurons of the SCN Are Critical for Interneuronal Coupling Regulating Circadian Behavior Rhythm

Mieda, M., Ono, D., Hasegawa, E., Okamoto, H., Honma, K., Honma, S., & Sakurai, T. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.005 · Cited by 254 · see citing works

Seasonal Encoding by the Circadian Pacemaker of the SCN

vanderLeest, H. T., Houben, T., Michel, S. H., Deboer, T., Albus, H., Vansteensel, M. J., Block, G. D., & Meijer, J. H. (2007) · Current Biology · doi:10.1016/j.cub.2007.01.048 · Cited by 253 · see citing works

Morning and evening circadian oscillations in the suprachiasmatic nucleus in vitro

Jagota, A., de la Iglesia, H. O., & Schwartz, W. J. (2000) · Nature Neuroscience · doi:10.1038/73943 · Cited by 246 · see citing works

Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

Webb, A. B., Angelo, N., Huettner, J. E., & Herzog, E. D. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902768106 · Cited by 236 · see citing works

Forced Desynchronization of Dual Circadian Oscillators within the Rat Suprachiasmatic Nucleus

de la Iglesia, H. O., Cambras, T., Schwartz, W. J., & Dı́ez-Noguera, A. (2004) · Current Biology · doi:10.1016/j.cub.2004.04.034 · Cited by 236 · see citing works

Two coupled oscillators: Simulations of the circadian pacemaker in mammalian activity rhythms

Daan, S., & Berde, C. B. (1978) · Journal of Theoretical Biology · doi:10.1016/0022-5193(78)90378-8 · Cited by 234 · see citing works

In Search of the Pathways for Light-Induced Pacemaker Resetting in the Suprachiasmatic Nucleus

Meijer, J. H., & Schwartz, W. J. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403018003006 · Cited by 226 · see citing works

Differential Resynchronisation of Circadian Clock Gene Expression within the Suprachiasmatic Nuclei of Mice Subjected to Experimental Jet Lag

Reddy, A. B., Field, M. D., Maywood, E. S., & Hastings, M. H. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-17-07326.2002 · Cited by 220 · see citing works

Luminance coding in a circadian pacemaker: the suprachiasmatic nucleus of the rat and the hamster

Meijer, J. H., Groos, G. A., & Rusak, B. (1986) · Brain Research · doi:10.1016/0006-8993(86)90117-4 · Cited by 220 · see citing works

Heterogeneity of rhythmic suprachiasmatic nucleus neurons: Implications for circadian waveform and photoperiodic encoding

Schaap, J., Albus, H., vanderLeest, H. T., Eilers, P. H. C., Détári, L., & Meijer, J. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2436298100 · Cited by 216 · see citing works

Two distinct oscillators in the rat suprachiasmatic nucleus in vitro.

Shinohara, K., Honma, S., Katsuno, Y., Abe, H., & Honma, K.-I. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.16.7396 · Cited by 215 · see citing works

Differential induction and localization of mPer1 and mPer2 during advancing and delaying phase shifts

Yan, L., & Silver, R. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02224.x · Cited by 208 · see citing works

Dynamic Interactions Mediated by Nonredundant Signaling Mechanisms Couple Circadian Clock Neurons

Evans, J. A., Leise, T., Castañón‐Cervantes, O., & Davidson, A. J. (2013) · Neuron · doi:10.1016/j.neuron.2013.08.022 · Cited by 199 · see citing works

Forty Years of Prcs-What Have We Learned?

Johnson, C. H. (1999) · Chronobiology International · doi:10.3109/07420529909016940 · Cited by 194 · see citing works

Electrical synapses coordinate activity in the suprachiasmatic nucleus

Long, M. A., Jutras, M. J., Connors, B. W., & Burwell, R. D. (2004) · Nature Neuroscience · doi:10.1038/nn1361 · Cited by 194 · see citing works

Vasopressin and the Output of the Hypothalamic Biological Clock

Kalsbeek, A., Fliers, E., Hofman, M. A., Swaab, D. F., & Buijs, R. M. (2010) · Journal of Neuroendocrinology · doi:10.1111/j.1365-2826.2010.01956.x · Cited by 192 · see citing works

Retinal ganglion cell projections to the hamster suprachiasmatic nucleus, intergeniculate leaflet, and visual midbrain: Bifurcation and melanopsin immunoreactivity

Morin, L. P., Blanchard, J. H., & Provencio, I. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10881 · Cited by 184 · see citing works

Vasoactive intestinal peptide and the mammalian circadian system

Vosko, A. M., Schroeder, A., Loh, D. H., & Colwell, C. S. (2007) · General and Comparative Endocrinology · doi:10.1016/j.ygcen.2007.04.018 · Cited by 183 · see citing works

Comparative Anatomy of the Mammalian Hypothalamic Suprachiasmatic Nucleus

Cassone, V. M., Speh, J. C., Card, J. P., & Moore, R. Y. (1988) · Journal of Biological Rhythms · doi:10.1177/074873048800300106 · Cited by 182 · see citing works

Neuromedin S-Producing Neurons Act as Essential Pacemakers in the Suprachiasmatic Nucleus to Couple Clock Neurons and Dictate Circadian Rhythms

Lee, I. T., Chang, A. S., Manandhar, M., Shan, Y., Fan, J., Izumo, M., Ikeda, Y., Motoike, T., Dixon, S., Seinfeld, J. E., et al. (2015) · Neuron · doi:10.1016/j.neuron.2015.02.006 · Cited by 180 · see citing works

Structure and function in circadian timing systems: Evidence for multiple coupled circadian oscillators

Rosenwasser, A. M., & Adler, N. T. (1986) · Neuroscience & Biobehavioral Reviews · doi:10.1016/0149-7634(86)90005-9 · Cited by 176 · see citing works

GABA-mediated repulsive coupling between circadian clock neurons in the SCN encodes seasonal time

Myung, J., Hong, S., DeWoskin, D., Schutter, E. D., Forger, D. B., & Takumi, T. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1421200112 · Cited by 174 · see citing works

Visualizing jet lag in the mouse suprachiasmatic nucleus and peripheral circadian timing system

Davidson, A. J., Castanon‐Cervantes, O., Leise, T. L., Molyneux, P. C., & Harrington, M. E. (2009) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06534.x · Cited by 171 · see citing works

Suprachiasmatic Nucleus Organization

Moore, R. Y., & Silver, R. (1998) · Chronobiology International · doi:10.3109/07420529808998703 · Cited by 166 · see citing works

The Suprachiasmatic Nucleus Entrains, But Does Not Sustain, Circadian Rhythmicity in the Olfactory Bulb

Granados‐Fuentes, D., Prolo, L. M., Abraham, U., & Herzog, E. D. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.4002-03.2004 · Cited by 156 · see citing works

Aging Differentially Affects the Re-entrainment Response of Central and Peripheral Circadian Oscillators

Sellix, M. T., Evans, J. A., Leise, T., Castañón‐Cervantes, O., Hill, D. D., Delisser, P., Block, G. D., Menaker, M., & Davidson, A. J. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.3559-12.2012 · Cited by 153 · see citing works

Complex circadian regulation of pineal melatonin and wheel-running in Syrian hamsters

Elliott, J. A., & Tamarkin, L. (1994) · Journal of Comparative Physiology A · doi:10.1007/bf00191713 · Cited by 152 · see citing works

SCN Organization Reconsidered

Morin, L. P. (2007) · Journal of Biological Rhythms · doi:10.1177/0748730406296749 · Cited by 151 · see citing works

Daily and circadian expression of neuropeptides in the suprachiasmatic nuclei of nocturnal and diurnal rodents

Dardente, H., Menet, J. S., Challet, É., Tournier, B. B., Pévet, P., & Masson‐Pévet, M. (2004) · Molecular Brain Research · doi:10.1016/j.molbrainres.2004.01.010 · Cited by 150 · see citing works

Cellular Level Brain Imaging in Behaving Mammals: An Engineering Approach

Hamel, E. O., Grewe, B. F., Parker, J. G., & Schnitzer, M. J. (2015) · Neuron · doi:10.1016/j.neuron.2015.03.055 · Cited by 147 · see citing works

Gradients in the circadian expression of Per1 and Per2 genes in the rat suprachiasmatic nucleus

Yan, L., & Okamura, H. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.01955.x · Cited by 146 · see citing works

Cellular communication in the circadian clock, the suprachiasmatic nucleus

van den Pol, A. N., & Dudek, F. E. (1993) · Neuroscience · doi:10.1016/0306-4522(93)90128-3 · Cited by 146 · see citing works

Distinct roles for GABA across multiple timescales in mammalian circadian timekeeping

DeWoskin, D., Myung, J., Belle, M. D. C., Piggins, H. D., Takumi, T., & Forger, D. B. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1420753112 · Cited by 143 · see citing works

Responses of neurones of the rat suprachiasmatic nucleus to retinal illumination under photopic and scotopic conditions

Aggelopoulos, N. C., & Meissl, H. (2000) · The Journal of Physiology · doi:10.1111/j.1469-7793.2000.t01-1-00211.x · Cited by 143 · see citing works

Phase Resetting Light Pulses InducePer1and Persistent Spike Activity in a Subpopulation of Biological Clock Neurons

Kuhlman, S. J., Silver, R., LeSauter, J., Bult‐Ito, A., & McMahon, D. G. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-04-01441.2003 · Cited by 142 · see citing works

Rhythmic coupling among cells in the suprachiasmatic nucleus

Colwell, C. S. (2000) · Journal of Neurobiology · doi:10.1002/1097-4695(20000615)43:4 · Cited by 139 · see citing works

The eye is necessary for a circadian rhythm in the suprachiasmatic nucleus

Lee, H. S., Nelms, J. L., Nguyen, M. M. N., Silver, R., & Lehman, M. N. (2003) · Nature Neuroscience · doi:10.1038/nn1006 · Cited by 138 · see citing works

Resetting the brain clock: time course and localization of mPER1 and mPER2 protein expression in suprachiasmatic nuclei during phase shifts

Yan, L., & Silver, R. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03189.x · Cited by 136 · see citing works

Circadian rhythms in mouse suprachiasmatic nucleus explants on multimicroelectrode plates.

Herzog, E., Geusz, M., Khalsa, S. B., Straume, M., & Block, G. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00337-5 · Cited by 133 · see citing works

Photoperiod differentially regulates the expression of Per1 and ICER in the pars tuberalis and the suprachiasmatic nucleus of the Siberian hamster

Messager, S., Hazlerigg, D. G., Mercer, J. G., & Morgan, P. J. (2000) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2000.00174.x · Cited by 130 · see citing works

Response curve, free-running period, and activity time in circadian locomotor rhythm of rats.

Honma, K., Honma, S., & Hiroshige, T. (1985) · The Japanese Journal of Physiology · doi:10.2170/jjphysiol.35.643 · Cited by 130 · see citing works

Calbindin-D28K cells in the hamster SCN express light-induced Fos

Silver, R., Romero, M.-T., Besmer, H. R., Leak, R. K., Nunez, J. M., & LeSauter, J. (1996) · Neuroreport · doi:10.1097/00001756-199604260-00026 · Cited by 130 · see citing works

A possible glial role in the mammalian circadian clock

Prosser, R. A., Edgar, D. M., Heller, H. C., & Miller, J. D. (1994) · Brain Research · doi:10.1016/0006-8993(94)90036-1 · Cited by 127 · see citing works

GABA Networks Destabilize Genetic Oscillations in the Circadian Pacemaker

Freeman, G. M., Krock, R. M., Aton, S. J., Thaben, P. F., & Herzog, E. D. (2013) · Neuron · doi:10.1016/j.neuron.2013.04.003 · Cited by 125 · see citing works

Gastrin-Releasing Peptide Promotes Suprachiasmatic Nuclei Cellular Rhythmicity in the Absence of Vasoactive Intestinal Polypeptide-VPAC2Receptor Signaling

Brown, T. M., Hughes, A. T. L., & Piggins, H. D. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.3821-05.2005 · Cited by 125 · see citing works

Gates and Oscillators: A Network Model of the Brain Clock

Antle, M. C., Foley, D. K., Foley, N. C., & Silver, R. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403253840 · Cited by 125 · see citing works

Two coupled neural oscillators as a model of the circadian pacemaker

Kawato, M., & Suzuki, R. (1980) · Journal of Theoretical Biology · doi:10.1016/0022-5193(80)90352-5 · Cited by 125 · see citing works

A neuropeptide speeds circadian entrainment by reducing intercellular synchrony

An, S., Harang, R., Meeker, K., Granados‐Fuentes, D., Tsai, C. A., Mazuski, C. N., Kim, J., Doyle, F. J., Petzold, L. R., & Herzog, E. D. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1307088110 · Cited by 122 · see citing works

Lateralization of Circadian Pacemaker Output: Activation of Left- and Right-Sided Luteinizing Hormone-Releasing Hormone Neurons Involves a Neural Rather Than a Humoral Pathway

de la Iglesia, H. O., Meyer, J. L., & Schwartz, W. J. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-19-07412.2003 · Cited by 122 · see citing works

Circadian Timing of REM Sleep Is Coupled to an Oscillator within the Dorsomedial Suprachiasmatic Nucleus

Lee, M. L., Swanson, B. E., & de la Iglesia, H. O. (2009) · Current Biology · doi:10.1016/j.cub.2009.03.051 · Cited by 120 · see citing works

Endogenous ultradian rhythms in rats exposed to prolonged continuous light

Honma, K., & Hiroshige, T. (1978) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1978.235.5.r250 · Cited by 120 · see citing works

Differential Response of Period 1 Expression within the Suprachiasmatic Nucleus

Nakamura, W. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.0889-05.2005 · Cited by 118 · see citing works

Seasonal induction of GABAergic excitation in the central mammalian clock

Farajnia, S., van Westering, T. L. E., Meijer, J. H., & Michel, S. H. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1319820111 · Cited by 117 · see citing works

Neuronal synchronization without calcium-dependent synaptic transmission in the hypothalamus.

Bouskila, Y., & Dudek, F. E. (1993) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.90.8.3207 · Cited by 116 · see citing works

Photoperiod-Nonresponsive Morphs: A Possible Variable in Microtine Population-Density Fluctuations

Nelson, R. J. (1987) · The American Naturalist · doi:10.1086/284715 · Cited by 115 · see citing works

Rhythmic multiunit neural activity in slices of hamster suprachiasmatic nucleus reflect prior photoperiod

Mrugała, M. M., Złomańczuk, P., Jagota, A., & Schwartz, W. J. (2000) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2000.278.4.r987 · Cited by 115 · see citing works

Regional pacemakers composed of multiple oscillator neurons in the rat suprachiasmatic nucleus

Nakamura, W., Honma, S., Shirakawa, T., & Honma, K.-I. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01684.x · Cited by 113 · see citing works

Temporal Precision in Circadian Systems: A Reliable Neuronal Clock from Unreliable Components?

Enright, J. T. (1980) · Science · doi:10.1126/science.7433976 · Cited by 112 · see citing works

Intrinsic Regulation of Spatiotemporal Organization within the Suprachiasmatic Nucleus

Evans, J. A., Leise, T., Castañón‐Cervantes, O., & Davidson, A. J. (2011) · PLoS ONE · doi:10.1371/journal.pone.0015869 · Cited by 111 · see citing works

Disrupted Neuronal Activity Rhythms in the Suprachiasmatic Nuclei of Vasoactive Intestinal Polypeptide-Deficient Mice

Brown, T. M., Colwell, C. S., Waschek, J. A., & Piggins, H. D. (2006) · Journal of Neurophysiology · doi:10.1152/jn.01206.2006 · Cited by 109 · see citing works

The Methamphetamine-Sensitive Circadian Oscillator (MASCO) in Mice

Tataroğlu, Ö., Davidson, A. J., Benvenuto, L. J., & Menaker, M. (2006) · Journal of Biological Rhythms · doi:10.1177/0748730406287529 · Cited by 109 · see citing works

Development of neuronal activity in the rat suprachiasmatic nucleus

Shibata, S., & Moore, R. Y. (1987) · Developmental Brain Research · doi:10.1016/0165-3806(87)90220-3 · Cited by 108 · see citing works

Overexpression of the human VPAC 2 receptor in the suprachiasmatic nucleus alters the circadian phenotype of mice

Shen, S., Spratt, C., Sheward, W. J., Kalló, I., West, K. M., Morrison, C. F., Coen, C. W., Marston, H. M., & Harmar, A. J. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.21.11575 · Cited by 107 · see citing works

Multiple Circadian Oscillators Regulate the Timing of Behavioral and Endocrine Rhythms in Female Golden Hamsters

Swann, J. M., & Turek, F. W. (1985) · Science · doi:10.1126/science.4001926 · Cited by 105 · see citing works

Evidence for differences in the circadian organization of hamsters exposed to short day photoperiod

Puchalski, W., & Lynch, G. R. (1986) · Journal of Comparative Physiology A · doi:10.1007/bf00612490 · Cited by 104 · see citing works

Clock Gene Daily Profiles and Their Phase Relationship in the Rat Suprachiasmatic Nucleus Are Affected by Photoperiod

Sumová, A., Jáč, M., Sládek, M., Šauman, I., & Illnerová, H. (2003) · Journal of Biological Rhythms · doi:10.1177/0748730403251801 · Cited by 104 · see citing works

Phase Shifting Capacity of the Circadian Pacemaker Determined by the SCN Neuronal Network Organization

vanderLeest, H. T., Rohling, J. H. T., Michel, S. H., & Meijer, J. H. (2009) · PLoS ONE · doi:10.1371/journal.pone.0004976 · Cited by 102 · see citing works

Photoperiod differentially regulates gene expression rhythms in the rostral and caudal SCN

Hazlerigg, D. G., Ebling, F. J. P., & Johnston, J. D. (2005) · Current Biology · doi:10.1016/j.cub.2005.06.010 · Cited by 101 · see citing works

Gastrin-Releasing Peptide Phase-Shifts Suprachiasmatic Nuclei Neuronal RhythmsIn Vitro

McArthur, A. J., Coogan, A. N., Ajpru, S., Sugden, D., Biello, S. M., & Piggins, H. D. (2000) · Journal of Neuroscience · doi:10.1523/jneurosci.20-14-05496.2000 · Cited by 101 · see citing works

Two Antiphase Oscillations Occur in Each Suprachiasmatic Nucleus of Behaviorally Split Hamsters

Yan, L., Foley, N. C., Bobula, J. M., Kriegsfeld, L. J., & Silver, R. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.2538-05.2005 · Cited by 99 · see citing works

Multiple hypothalamic cell populations encoding distinct visual information

Brown, T. M., Wynne, J., Piggins, H. D., & Lucas, R. J. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2010.199877 · Cited by 98 · see citing works

Differential regulation of fos family genes in the ventrolateral and dorsomedial subdivisions of the rat suprachiasmatic nucleus

Schwartz, W. J., Carpino, A., de la Iglesia, H. O., Baler, R., Klein, D. C., Nakabeppu, Y., & D, N. A. M. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00140-8 · Cited by 98 · see citing works

Dopamine receptor 1 neurons in the dorsal striatum regulate food anticipatory circadian activity rhythms in mice

Gallardo, C. M., Darvas, M., Oviatt, M., Chang, C. H., Michalik, M. J., Huddy, T. F., Meyer, E. E., Shuster, S. A., Aguayo, A., Hill, E. M., et al. (2014) · eLife · doi:10.7554/elife.03781 · Cited by 98 · see citing works

Lhx1 Controls Terminal Differentiation and Circadian Function of the Suprachiasmatic Nucleus

Bedont, J. L., LeGates, T. A., Slat, E. A., Byerly, M. S., Wang, H., Hu, J., Rupp, A. C., Qian, J. X., Wong, G. W., Herzog, E. D., et al. (2014) · Cell Reports · doi:10.1016/j.celrep.2014.03.060 · Cited by 98 · see citing works

Reorganization of the Suprachiasmatic Nucleus Coding for Day Length

Naito, E., Watanabe, T., Tei, H., Yoshimura, T., & Ebihara, S. (2008) · Journal of Biological Rhythms · doi:10.1177/0748730408314572 · Cited by 98 · see citing works

Na V 1.1 channels are critical for intercellular communication in the suprachiasmatic nucleus and for normal circadian rhythms

Han, S., Yu, F. H., Schwartz, M. D., Linton, J. D., Bosma, M. M., Hurley, J. B., Catterall, W. A., & de la Iglesia, H. O. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1115729109 · Cited by 97 · see citing works

The Circadian Component in Photoperiodic Induction

Pittendrigh, C. S., Elliott, J. A., & Takamura, T. (1984) · Novartis Foundation symposium · doi:10.1002/9780470720851.ch4 · Cited by 96 · see citing works

Gastrin-Releasing Peptide Mediates Light-Like Resetting of the Suprachiasmatic Nucleus Circadian Pacemaker through cAMP Response Element-Binding Protein andPer1Activation

Gamble, K. L., Allen, G. C., Zhou, T., & McMahon, D. G. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.1109-07.2007 · Cited by 96 · see citing works

Prokineticin 2 and circadian clock output

Zhou, Q., & Cheng, M. (2005) · FEBS Journal · doi:10.1111/j.1742-4658.2005.04984.x · Cited by 92 · see citing works

Spatiotemporal Heterogeneity in the Electrical Activity of Suprachiasmatic Nuclei Neurons and their Response to Photoperiod

Brown, T. M., & Piggins, H. D. (2009) · Journal of Biological Rhythms · doi:10.1177/0748730408327918 · Cited by 92 · see citing works

Circadian rhythms in the rat: Constant darkness, entrainment to T cycles and to skeleton photoperiods

Stephan, F. K. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90152-x · Cited by 91 · see citing works

Photoperiod regulates multiple gene expression in the suprachiasmatic nuclei and pars tuberalis of the Siberian hamster (Phodopus sungorus)

Johnston, J. D., Ebling, F. J. P., & Hazlerigg, D. G. (2005) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2005.04148.x · Cited by 91 · see citing works

Per and neuropeptide expression in the rat suprachiasmatic nuclei: compartmentalization and differential cellular induction by light

Dardente, H., Poirel, V., Klosen, P., Pévet, P., & Masson‐Pévet, M. (2002) · Brain Research · doi:10.1016/s0006-8993(02)03563-1 · Cited by 88 · see citing works

Light-Induced Phase Shifts in tau Mutant Hamsters

Shimomura, K., & Menaker, M. (1994) · Journal of Biological Rhythms · doi:10.1177/074873049400900201 · Cited by 87 · see citing works

Dissociation of circadian and light inhibition of melatonin release through forced desynchronization in the rat

Schwartz, M. D., Wotus, C., Liu, T., Friesen, W. O., Borjigin, J., Oda, G. A., & de la Iglesia, H. O. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906382106 · Cited by 86 · see citing works

Circadian Rhythm in Inhibitory Synaptic Transmission in the Mouse Suprachiasmatic Nucleus

Itri, J. N., Michel, S. H., Waschek, J. A., & Colwell, C. S. (2004) · Journal of Neurophysiology · doi:10.1152/jn.01078.2003 · Cited by 83 · see citing works

Light selectively alters vasoactive intestinal peptide and peptide histidine isoleucine immunoreactivity within the rat suprachiasmatic nucleus

Albers, H. E., Minamitani, N., Stopa, E. G., & Ferris, C. F. (1987) · Brain Research · doi:10.1016/0006-8993(87)91544-7 · Cited by 82 · see citing works

Twenty-four-hour melatonin and core body temperature rhythms: their adaptation in night workers

Weibel, L., Spiegel, K., Gronfier, C., FOLLENIUS, M., & BRANDENBERGER, G. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.3.r948 · Cited by 81 · see citing works

The Two-Oscillator Circadian System of Tree Shrews (Tupaia belangeri) and Its Response to Light and Dark Pulses

Meijer, J. H., Daan, S., Overkamp, G. J. F., & Hermann, P. (1990) · Journal of Biological Rhythms · doi:10.1177/074873049000500101 · Cited by 81 · see citing works

The suprachiasmatic nuclei: Two circadian clocks?

Pickard, G. E., & Turek, F. W. (1983) · Brain Research · doi:10.1016/0006-8993(83)90486-9 · Cited by 80 · see citing works

Circadian Control of Mouse Heart Rate and Blood Pressure by the Suprachiasmatic Nuclei: Behavioral Effects Are More Significant than Direct Outputs

Sheward, W. J., Naylor, E., Knowles-Barley, S., Armstrong, J. D., Brooker, G. A., Seckl, J. R., Turek, F. W., Holmes, M. C., Zee, P. C., & Harmar, A. J. (2010) · PLoS ONE · doi:10.1371/journal.pone.0009783 · Cited by 79 · see citing works

Photic responses of suprachiasmatic area neurons in diurnal degus (Octodon degus) and nocturnal rats (Rattus norvegicus).

Jiao, Y.-Y., Lee, T. M., & Rusak, B. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01218-9 · Cited by 78 · see citing works

Unilateral lesions of the hamster suprachiasmatic nuclei: evidence for redundant control of circadian rhythms

Davis, F. C., & Gorski, R. A. (1984) · Journal of Comparative Physiology A · doi:10.1007/bf00604987 · Cited by 78 · see citing works

Period Coding of Bmal1 Oscillators in the Suprachiasmatic Nucleus

Myung, J., Hong, S., Hatanaka, F., Nakajima, Y., Schutter, E. D., & Takumi, T. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.5586-11.2012 · Cited by 76 · see citing works

The Dorsomedial Suprachiasmatic Nucleus Times Circadian Expression of Kiss1 and the Luteinizing Hormone Surge

Smarr, B. L., Morris, E. L., & de la Iglesia, H. O. (2012) · Endocrinology · doi:10.1210/en.2011-1857 · Cited by 75 · see citing works

Shell neurons of the master circadian clock coordinate the phase of tissue clocks throughout the brain and body

Evans, J. A., Suen, T.-C., Callif, B. L., Mitchell, A. S., Castañón‐Cervantes, O., Baker, K. M., Kloehn, I., Baba, K., Teubner, B. J. W., Ehlen, J. C., et al. (2015) · BMC Biology · doi:10.1186/s12915-015-0157-x · Cited by 75 · see citing works

Metabolic rhythm abnormalities in mice lacking VIP-VPAC2signaling

Bechtold, D. A., Brown, T. M., Luckman, S. M., & Piggins, H. D. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00667.2007 · Cited by 75 · see citing works

Calbindin neurons in the hamster suprachiasmatic nucleus do not exhibit a circadian variation in spontaneous firing rate

Jobst, E. E., & Allen, C. N. (2002) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2002.02309.x · Cited by 75 · see citing works

CELLULAR COMMUNICATION AND COUPLING WITHIN THE SUPRACHIASMATIC NUCLEUS

Michel, S. H., Colwell, C. S., & Colwell, C. S. (2001) · Chronobiology International · doi:10.1081/cbi-100106074 · Cited by 74 · see citing works

Characterization of circadian function in Djungarian hamsters insensitive to short day photoperiod

Puchalski, W., & Lynch, G. R. (1988) · Journal of Comparative Physiology A · doi:10.1007/bf00606119 · Cited by 72 · see citing works

Environmental induction of photononresponsiveness in the Siberian hamster, Phodopus sungorus

Gorman, M. R., & Zucker, I. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.3.r887 · Cited by 71 · see citing works

Entrainment of activity to multiple feeding times in rats with suprachiasmatic lesions

Stephan, F. K. (1989) · Physiology & Behavior · doi:10.1016/0031-9384(89)90026-7 · Cited by 70 · see citing works

MULTIPLE OSCILLATORS IN THE SUPRACHIASMATIC NUCLEUS

Shirakawa, T., Honma, S., & Honma, K. (2001) · Chronobiology International · doi:10.1081/cbi-100103962 · Cited by 70 · see citing works

Photic Entrainment of the Mammalian Rhythm in Melatonin Production

Illnerová, H., & Sumová, A. (1997) · Journal of Biological Rhythms · doi:10.1177/074873049701200609 · Cited by 68 · see citing works

Tracer and electrical coupling of rat suprachiasmatic nucleus neurons

Jiang, Z.-G., Yang, Y.-Q., & Allen, C. N. (1997) · Neuroscience · doi:10.1016/s0306-4522(96)00539-8 · Cited by 67 · see citing works

Effect of asymmetrical reductions of photoperiod on pineal melatonin, locomotor activity and gonadal condition of male Syrian hamsters

Hastings, M. H., Walker, A. P., & Herbert, J. (1987) · Journal of Endocrinology · doi:10.1677/joe.0.1140221 · Cited by 67 · see citing works

The clock in the dorsal suprachiasmatic nucleus runs faster than that in the ventral

Noguchi, T., Watanabe, K., Ogura, A., & Yamaoka, S. (2004) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2004.03784.x · Cited by 67 · see citing works

Splitting of wheelrunning rhythms by castrated or steroid treated male and female hamsters

Morin, L. P., & Cummings, L. A. (1982) · Physiology & Behavior · doi:10.1016/0031-9384(82)90236-0 · Cited by 66 · see citing works

Tetrodotoxin does not affect circadian rhythms in neuronal activity and metabolism in rodent suprachiasmatic nucleus in vitro.

Shibata, S., & Moore, R. (1993) · Brain Research · doi:10.1016/0006-8993(93)90993-w · Cited by 66 · see citing works

Disrupted Reproduction, Estrous Cycle, and Circadian Rhythms in Female Mice Deficient in Vasoactive Intestinal Peptide

Loh, D. H., Kuljis, D. A., Azuma, L., Wu, Y., Truong, D. A., Wang, H. B., & Colwell, C. S. (2014) · Journal of Biological Rhythms · doi:10.1177/0748730414549767 · Cited by 65 · see citing works

Phase Resetting of the Mammalian Circadian Clock Relies on a Rapid Shift of a Small Population of Pacemaker Neurons

Rohling, J. H. T., vanderLeest, H. T., Michel, S. H., Vansteensel, M. J., & Meijer, J. H. (2011) · PLoS ONE · doi:10.1371/journal.pone.0025437 · Cited by 65 · see citing works

Population Encoding by Circadian Clock Neurons Organizes Circadian Behavior

Ciarleglio, C. M., Gamble, K. L., Axley, J. C., Strauss, B. R., Cohen, J. Y., Colwell, C. S., & McMahon, D. G. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.3801-08.2009 · Cited by 65 · see citing works

Search for the feeding-entrainable circadian oscillator: a complex proposition

Davidson, A. J. (2006) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00073.2006 · Cited by 64 · see citing works

Circadian Effects of Light No Brighter Than Moonlight

Evans, J. A., Elliott, J. A., & Gorman, M. R. (2007) · Journal of Biological Rhythms · doi:10.1177/0748730407301988 · Cited by 64 · see citing works

In vitro electrical activity in the suprachiasmatic nucleus following splitting and masking of wheel-running behavior

Złomańczuk, P., Margraf, R. R., & Lynch, G. R. (1991) · Brain Research · doi:10.1016/0006-8993(91)90291-3 · Cited by 62 · see citing works

In Syrian and European hamsters, the duration of sensitive phase to light of the suprachiasmatic nuclei depends on the photoperiod

Vuillez, P., Jacob, N., Teclemariam‐Mesbah, R., & Pévet, P. (1996) · Neuroscience Letters · doi:10.1016/0304-3940(96)12535-0 · Cited by 61 · see citing works

Rhythm-Promoting Actions of Exercise in Mice with Deficient Neuropeptide Signaling

Power, A., Hughes, A. T. L., Samuels, R. E., & Piggins, H. D. (2010) · Journal of Biological Rhythms · doi:10.1177/0748730410374446 · Cited by 60 · see citing works

GABAergic modulation of gap junction communication in slice cultures of the rat suprachiasmatic nucleus

Shinohara, K., Hiruma, H., Funabashi, T., & Kimura, F. (2000) · Neuroscience · doi:10.1016/s0306-4522(99)00556-4 · Cited by 59 · see citing works

Gap junctions couple astrocytes but not neurons in dissociated cultures of rat suprachiasmatic nucleus

Welsh, D. K., & Reppert, S. M. (1996) · Brain Research · doi:10.1016/0006-8993(95)01172-2 · Cited by 59 · see citing works

Dissociation of the Rat Motor Activity Rhythm Under T Cycles Shorter Than 24 Hours

Campuzano, A., Vilaplana, J., Cambras, T., & Dı́ez-Noguera, A. (1998) · Physiology & Behavior · doi:10.1016/s0031-9384(97)00416-2 · Cited by 59 · see citing works

Live imaging of altered period1 expression in the suprachiasmatic nuclei of Vipr2−/− mice1

Hughes, A. T. L., Guilding, C., Lennox, L., Samuels, R. E., McMahon, D. G., & Piggins, H. D. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05520.x · Cited by 59 · see citing works

Internal organization of the circadian timing system in multicellular animals.

Moore‐Ede, M. C., Schmelzer, W. S., Kass, D., & Herd, J. A. (1976) · PubMed · Cited by 59 · see citing works

Behavioural rhythm splitting in the CS mouse is related to clock gene expression outside the suprachiasmatic nucleus

Abe, H., Honma, S., Namihira, M., Masubuchi, S., & Honma, K.-I. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01732.x · Cited by 58 · see citing works

Quantitative Peptidomics for Discovery of Circadian-Related Peptides from the Rat Suprachiasmatic Nucleus

Lee, J. E., Zamdborg, L., Southey, B. R., Atkins, N., Mitchell, J. W., Li, M., Gillette, M. U., Kelleher, N. L., & Sweedler, J. V. (2012) · Journal of Proteome Research · doi:10.1021/pr300605p · Cited by 57 · see citing works

Circadian characteristics of Djungarian hamsters: effects of photoperiodic pretreatment and artificial selection

Puchalski, W., & Lynch, G. R. (1991) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1991.261.3.r670 · Cited by 56 · see citing works

Photoperiodism in Hamsters: Abrupt Versus Gradual Changes in Day Length Differentially Entrain Morning and Evening Circadian Oscillators

Gorman, M. R., Freeman, D. A., & Zucker, I. (1997) · Journal of Biological Rhythms · doi:10.1177/074873049701200204 · Cited by 55 · see citing works

Splitting of the Circadian Rhythm of Activity in Hamsters

Turek, F. W., Earnest, D. J., & Swann, J. M. (1982) · Proceedings in life sciences · doi:10.1007/978-3-642-68651-1_22 · Cited by 54 · see citing works

A hVIPR transgene as a novel tool for the analysis of circadian function in the mouse suprachiasmatic nucleus

King, V. M., Chahad‐Ehlers, S., Shen, S., Harmar, A. J., Maywood, E. S., & Hastings, M. H. (2003) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.2003.02487.x · Cited by 53 · see citing works

Evidence that the Circadian System Mediates Photoperiodic Nonresponsiveness in Siberian Hamsters: The Effect of Running Wheel Access on Photoperiodic Responsiveness

Freeman, D. A., & Goldman, B. D. (1997) · Journal of Biological Rhythms · doi:10.1177/074873049701200202 · Cited by 53 · see citing works

Role of vasoactive intestinal peptide in seasonal encoding by the suprachiasmatic nucleus clock

Lucassen, E. A., van Diepen, H. C., Houben, T., Michel, S. H., Colwell, C. S., & Meijer, J. H. (2012) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2012.08054.x · Cited by 52 · see citing works

The effects of continuous light exposure on Syrian hamster suprachiasmatic (SCN) neuronal discharge activity in vitro

Mason, R. (1991) · Neuroscience Letters · doi:10.1016/0304-3940(91)90920-o · Cited by 52 · see citing works

Melanopsin—Shedding Light on the Elusive Circadian Photopigment

Brown, R. L., & Robinson, P. R. (2004) · Chronobiology International · doi:10.1081/cbi-120037816 · Cited by 51 · see citing works

Hypothalamic Integration of Metabolic, Endocrine, and Circadian Signals in Fish: Involvement in the Control of Food Intake

Delgado, M. J., Cerdá‐Reverter, J. M., & Soengas, J. L. (2017) · Frontiers in Neuroscience · doi:10.3389/fnins.2017.00354 · Cited by 163 · see citing works

Molecular Links between the Circadian Clock and the Cell Cycle

Farshadi, E. A., van der Horst, G. T. J., & Chaves, I. (2020) · Journal of Molecular Biology · doi:10.1016/j.jmb.2020.04.003 · Cited by 162 · see citing works

The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus

Albers, H. E., Walton, J. C., Gamble, K. L., McNeill, J. K., & Hummer, D. L. (2016) · Frontiers in Neuroendocrinology · doi:10.1016/j.yfrne.2016.11.003 · Cited by 113 · see citing works

Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus

Carmona‐Alcocer, V., Abel, J. H., Sun, T. C., Petzold, L. R., Doyle, F. J., Simms, C. L., & Herzog, E. D. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.2006-17.2017 · Cited by 98 · see citing works

Output from VIP cells of the mammalian central clock regulates daily physiological rhythms

Paul, S., Hanna, L., Harding, C., Hayter, E. A., Walmsley, L., Bechtold, D. A., & Brown, T. M. (2020) · Nature Communications · doi:10.1038/s41467-020-15277-x · Cited by 78 · see citing works

The flexible clock: predictive and reactive homeostasis, energy balance and the circadian regulation of sleep–wake timing

Riede, S. J., van der Vinne, V., & Hut, R. A. (2017) · Journal of Experimental Biology · doi:10.1242/jeb.130757 · Cited by 76 · see citing works

Collective timekeeping among cells of the master circadian clock

Evans, J. A. (2016) · Journal of Endocrinology · doi:10.1530/joe-16-0054 · Cited by 77 · see citing works

Using light to tell the time of day: sensory coding in the mammalian circadian visual network

Brown, T. M. (2016) · Journal of Experimental Biology · doi:10.1242/jeb.132167 · Cited by 70 · see citing works

Sex differences in daily timekeeping and circadian clock circuits

Joye, D. A. M., & Evans, J. A. (2021) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2021.04.026 · Cited by 61 · see citing works

Evidence for Weakened Intercellular Coupling in the Mammalian Circadian Clock under Long Photoperiod

Buijink, M. R., Almog, A., Wit, C. B., Roethler, O., Engberink, A. H. O. O., Meijer, J. H., Garlaschelli, D., Rohling, J. H. T., & Michel, S. H. (2016) · PLoS ONE · doi:10.1371/journal.pone.0168954 · Cited by 48 · see citing works

Seasonal plasticity in GABAA signaling is necessary for restoring phase synchrony in the master circadian clock network

Rohr, K. E., Pancholi, H., Haider, S., Karow, C., Modert, D., Raddatz, N. J., & Evans, J. A. (2019) · eLife · doi:10.7554/elife.49578 · Cited by 46 · see citing works

Naturalistic Intensities of Light at Night: A Review of the Potent Effects of Very Dim Light on Circadian Responses and Considerations for Translational Research

Walbeek, T. J., Harrison, E. M., Gorman, M. R., & Glickman, G. L. (2021) · Frontiers in Neurology · doi:10.3389/fneur.2021.625334 · Cited by 38 · see citing works

Circuit development in the master clock network of mammals

Carmona‐Alcocer, V., Rohr, K. E., Joye, D. A. M., & Evans, J. A. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14259 · Cited by 37 · see citing works

Vasopressin regulates daily rhythms and circadian clock circuits in a manner influenced by sex

Rohr, K. E., Telega, A., Savaglio, A., & Evans, J. A. (2021) · Hormones and Behavior · doi:10.1016/j.yhbeh.2020.104888 · Cited by 35 · see citing works

Bipolar mood cycles associated with lunar entrainment of a circadian rhythm

Wehr, T. A. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0203-x · Cited by 33 · see citing works

Resynchronization Dynamics Reveal that the Ventral Entrains the Dorsal Suprachiasmatic Nucleus

Taylor, S. R., Wang, T. J., Granados‐Fuentes, D., & Herzog, E. D. (2016) · Journal of Biological Rhythms · doi:10.1177/0748730416680904 · Cited by 31 · see citing works

Asymmetric vasopressin signaling spatially organizes the master circadian clock

Bedont, J. L., Rohr, K. E., Bathini, A., Hattar, S. S., Blackshaw, S., Sehgal, A., & Evans, J. A. (2018) · The Journal of Comparative Neurology · doi:10.1002/cne.24478 · Cited by 28 · see citing works

Macroscopic Models for Human Circadian Rhythms

Hannay, K. M., Booth, V., & Forger, D. B. (2019) · Journal of Biological Rhythms · doi:10.1177/0748730419878298 · Cited by 30 · see citing works

Temporal Regulation of GABAAReceptor Subunit Expression: Role in Synaptic and Extrasynaptic Communication in the Suprachiasmatic Nucleus

Walton, J. C., McNeill, J. K., Oliver, K. A., & Albers, H. E. (2017) · eNeuro · doi:10.1523/eneuro.0352-16.2017 · Cited by 25 · see citing works

Recurring circadian disruption alters circadian clock sensitivity to resetting

Leise, T., Goldberg, A., Michael, J., Montoya, G., Solow, S., Molyneux, P. C., Vetrivelan, R., & Harrington, M. E. (2018) · European Journal of Neuroscience · doi:10.1111/ejn.14179 · Cited by 22 · see citing works

The circadian clock: a tale of genetic–electrical interplay and synaptic integration

Belle, M. D. C., & Allen, C. N. (2018) · Current Opinion in Physiology · doi:10.1016/j.cophys.2018.08.002 · Cited by 21 · see citing works

Seasonality and light phase-resetting in the mammalian circadian rhythm

Hannay, K. M., Forger, D. B., & Booth, V. (2020) · Scientific Reports · doi:10.1038/s41598-020-74002-2 · Cited by 19 · see citing works

Rhythmic astrocytic GABA production synchronizes neuronal circadian timekeeping in the suprachiasmatic nucleus

Ness, N., Díaz-Clavero, S., Hoekstra, M. M., & Brancaccio, M. (2024) · The EMBO Journal · doi:10.1038/s44318-024-00324-w · Cited by 17 · see citing works

Generation and Disruption of Circadian Rhythms in the Suprachiasmatic Nucleus: A Core-Shell Model

Goltsev, A. V., Wright, E. A. P., Mendes, J. F. F., & Yoon, S. Y. (2022) · Journal of Biological Rhythms · doi:10.1177/07487304221107834 · Cited by 13 · see citing works

The transcription factor VAX1 in VIP neurons of the suprachiasmatic nucleus impacts circadian rhythm generation, depressive-like behavior, and the reproductive axis in a sex-specific manner in mice

Loh, B. M. V., Yaw, A. M., Breuer, J. A., Jackson, B., Nguyen, D., Jang, K., Ramos, F., Ho, E. V., Cui, L. J., Gillette, D., et al. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1269672 · Cited by 12 · see citing works

Food anticipatory circadian rhythms in mice entrained to long or short day photoperiods

Power, S. C., & Mistlberger, R. E. (2020) · Physiology & Behavior · doi:10.1016/j.physbeh.2020.112939 · Cited by 12 · see citing works

Dissociation between two subgroups of the suprachiasmatic nucleus affected by the number of damped oscillated neurons

Gu, C., Yang, H., & Rohling, J. H. T. (2017) · Physical review. E · doi:10.1103/physreve.95.032302 · Cited by 12 · see citing works

Decapentaplegic Acutely Defines the Connectivity of Central Pacemaker Neurons in Drosophila

Polcowñuk, S., Yoshii, T., & Ceriani, M. F. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0397-21.2021 · Cited by 11 · see citing works

A Meta-Analysis Characterizing Stem-Like Gene Expression in the Suprachiasmatic Nucleus and Its Circadian Clock

Beligala, D. H., De, A., & Geusz, M. E. (2018) · BioMed Research International · doi:10.1155/2018/3610603 · Cited by 9 · see citing works

Gap junction protein Innexin2 modulates the period of free-running rhythms in Drosophila melanogaster

Ramakrishnan, A., & Sheeba, V. (2021) · iScience · doi:10.1016/j.isci.2021.103011 · Cited by 9 · see citing works

Pineal Gland—A Spiritual Third Eye: An Odyssey of Antiquity to Modern Chronomedicine

Kumar, R., Kumar, A., & Sardhara, J. (2018) · Indian Journal of Neurosurgery · doi:10.1055/s-0038-1649524 · Cited by 9 · see citing works

Desipramine restores the alterations in circadian entrainment induced by prenatal exposure to glucocorticoids

Spulber, S. D., Conti, M., Elberling, F., Raciti, M., Borroto‐Escuela, D. O., Fuxé, K., & Ceccatelli, S. (2019) · Translational Psychiatry · doi:10.1038/s41398-019-0594-3 · Cited by 8 · see citing works

Midday meals do not impair mouse memory

Power, S. C., Michalik, M. J., Couture-Nowak, S., Kent, B. A., & Mistlberger, R. E. (2018) · Scientific Reports · doi:10.1038/s41598-018-35427-y · Cited by 8 · see citing works

Electromagnetic radiation and biophoton emission in neuronal communication and neurodegenerative diseases

Erboz, A., Kesekler, E., Gentili, P. L., Uversky, V. N., & Coskuner‐Weber, O. (2024) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2024.12.004 · Cited by 7 · see citing works

Modelling the functional roles of synaptic and extra-synaptic γ-aminobutyric acid receptor dynamics in circadian timekeeping

Sueviriyapan, N., Granados‐Fuentes, D., Simon, T., Herzog, E. D., & Henson, M. A. (2021) · Journal of The Royal Society Interface · doi:10.1098/rsif.2021.0454 · Cited by 7 · see citing works

The cell adhesion molecule EphA4 is involved in circadian clock functions

Kießling, S., O’Callaghan, E. K., Freyburger, M., Cermakian, N., & Mongrain, V. (2017) · Genes Brain & Behavior · doi:10.1111/gbb.12387 · Cited by 7 · see citing works

Enhanced Circadian Entrainment in Mice and Its Utility under Human Shiftwork Schedules

Walbeek, T. J., Harrison, E. M., Soler, R. R., & Gorman, M. R. (2019) · Clocks & Sleep · doi:10.3390/clockssleep1030032 · Cited by 5 · see citing works

Functional interactions between neurotransmitters and neuropeptides in regulating suprachiasmatic nucleus function and circadian rhythms

Reghunandanan, V. (2024) · Exploration of neuroscience · doi:10.37349/en.2024.00059 · Cited by 4 · see citing works

Modified Wavelet Analyses Permit Quantification of Dynamic Interactions Between Ultradian and Circadian Rhythms

Riggle, J. P., Kay, L. M., Onishi, K. G., Falk, D. T., Smarr, B. L., Zucker, I., & Prendergast, B. J. (2022) · Journal of Biological Rhythms · doi:10.1177/07487304221128652 · Cited by 4 · see citing works

First In Situ Identification of Ultradian and Infradian Rhythms, and Nocturnal Locomotion Activities of Four Colonies of Red Wood Ants ( Formica rufa -Group)

Berberich, G. M., Berberich, M. B., Ellison, A. M., Grumpe, A., & Wöhler, C. (2019) · Journal of Biological Rhythms · doi:10.1177/0748730418821446 · Cited by 4 · see citing works

Modeling of Jet Lag and Searching for an Optimal Light Treatment

Aleixo, B., Yoon, S. Y., Mendes, J. F. F., & Goltsev, A. V. (2025) · Journal of Biological Rhythms · doi:10.1177/07487304241306851 · Cited by 3 · see citing works

Model Research on the Influence of the Biological Clock Network Structure on Function Under Light Stimulation

Feng, J., Zheng, W., & Gu, C. (2025) · Symmetry · doi:10.3390/sym17091418 · Cited by 2 · see citing works

Astrocytes in the Circadian System: A Promising Target for Mood Disorder Interventions

Liu, P., Li, H., Zhu, Y., Song, S., Kang, L., & Hu, Y. (2026) · Journal of Integrative Neuroscience · doi:10.31083/jin48501 · Cited by 1 · see citing works

Circadian Rhythm of Patients with Disorders of Consciousness

Di, H. (2018) · Open access Journal of Neurology & Neurosurgery · doi:10.19080/oajnn.2018.09.555763 · Cited by 1 · see citing works

Chronobiology and Chronotherapy in Depression: Current Knowledge and Chronotherapeutic Promises

Rojas, M., Chávez-Castillo, M., Pírela, D., Ortega, Á., Salazar, J. J., Cano, C., Chacín, M., Riaño-Garzón, M., Batista, M. J., Díaz-Camargo, E. A., et al. (2020) · Current Psychiatry Research and Reviews · doi:10.2174/2666082216999201124152432 · Cited by 1 · see citing works

PINEAL GLAND: HISTORICAL EXCURSION AND CURRENT SCIENTIFIC FACTS (LITERATURE REVIEW)

Semenenko, S. B., Slobodian, K. V., Dzhuriak, V., Chernei, N. Y., & Rudan, K. V. (2024) · Clinical & experimental pathology · doi:10.24061/1727-4338.xxiii.2.88.2024.17

Circadian Behavioral and Bioluminescence Rhythms in the Per2 LUC Syrian Hamster

Liu, Y., Roszkowski, E., Li, R., Sisson, C., Landman, E., Weaver, D. R., Wang, Z., Evans, J. A., & Bittman, E. L. (2026) · Journal of Biological Rhythms · doi:10.1177/07487304261459487

Neurons in rat suprachiasmatic nucleus exhibit variable ultradian cycles and retain the rhythmic firing patterns entrained by periodic stimuli

Song, H., Shao, P., Li, X., Wang, Y., & Li, D. (2026) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2026.154368

Come Together, Right…Now: Synchronization of Rhythms in a Mammalian Circadian Clock

Aton, S. J., & Herzog, E. D. (2005) · Neuron · doi:10.1016/j.neuron.2005.11.001 · Cited by 288 · see citing works

The clock shop: Coupled circadian oscillators

Granados‐Fuentes, D., & Herzog, E. D. (2012) · Experimental Neurology · doi:10.1016/j.expneurol.2012.10.011 · Cited by 30 · see citing works

Cell autonomy and synchrony of suprachiasmatic nucleus circadian oscillators

Mohawk, J. A., & Takahashi, J. S. (2011) · Trends in Neurosciences · doi:10.1016/j.tins.2011.05.003 · Cited by 247 · see citing works

Regulating the Suprachiasmatic Nucleus (SCN) Circadian Clockwork: Interplay between Cell-Autonomous and Circuit-Level MechanismsPreprint

Herzog, E. D., Hermanstyne, T. O., Smyllie, N. J., & Hastings, M. H. (2017) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a027706 · Cited by 268 · see citing works

Suprachiasmatic nucleus

Honma, S., Ono, D., Suzuki, Y., Inagaki, N., Yoshikawa, T., Nakamura, W., & Honma, K.-I. (2012) · Progress in brain research · doi:10.1016/b978-0-444-59427-3.00029-0 · Cited by 59 · see citing works