Autophagy and apoptosis dysfunction in neurodegenerative disorders

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

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Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

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Autophagy fights disease through cellular self-digestion

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

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Alzheimer’s disease

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Inflammation and Alzheimer’s disease

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Microglia: a sensor for pathological events in the CNS

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Autophagy: process and functionPreprint

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Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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Autophagy: cellular and molecular mechanisms

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Mitochondrial Fission, Fusion, and Stress

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Mechanisms underlying inflammation in neurodegeneration

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Loss of autophagy in the central nervous system causes neurodegeneration in mice

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TFEB Links Autophagy to Lysosomal Biogenesis

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Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

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Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology

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Reactive microglia are positive for HLA‐DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

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Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

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PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

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Huntington's disease

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Programmed Cell Death in Animal Development

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TDP-43 Mutations in Familial and Sporadic Amyotrophic Lateral Sclerosis

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Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

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Molecular mechanisms of necroptosis: an ordered cellular explosion

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Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease

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Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages

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Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

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Autophagy and Aging

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Impaired Degradation of Mutant α-Synuclein by Chaperone-Mediated Autophagy

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Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

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Programmed Cell Death in Animal Development and Disease

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Amyotrophic Lateral Sclerosis

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α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro

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Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

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Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

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Regulation of Mammalian Autophagy in Physiology and Pathophysiology

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Alzheimer Mechanisms and Therapeutic Strategies

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The roles of intracellular protein-degradation pathways in neurodegeneration

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Control of microglial neurotoxicity by the fractalkine receptor

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A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

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ER Stress Triggers Apoptosis by Activating BH3-Only Protein Bim

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Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

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Lysosomal membrane permeabilization in cell death

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Mitochondrial abnormalities in Alzheimer's disease

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Lysosomes and autophagy in cell death control

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ABAD Directly Links Aß to Mitochondrial Toxicity in Alzheimer's Disease

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Neuronal α-Synucleinopathy with Severe Movement Disorder in Mice Expressing A53T Human α-Synuclein

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Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS

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Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein

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Apaf1 Is Required for Mitochondrial Pathways of Apoptosis and Brain Development

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Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

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Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy

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SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

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α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration

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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis

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Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

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Autophagic Cell Death and Its Execution by Lysosomal Cathepsins.

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Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

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Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin

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Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession

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β-Amyloid1–42Induces Neuronal Death through the p75 Neurotrophin Receptor

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Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

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A Short Mitochondrial Form of p19ARF Induces Autophagy and Caspase-Independent Cell Death

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Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: Involvement of endoplasmic reticulum calcium release in oligomer-induced cell death

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CHOP Potentially Co-Operates with FOXO3a in Neuronal Cells to Regulate PUMA and BIM Expression in Response to ER Stress

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Novel synthetic small‐molecule activators of AMPK as enhancers of autophagy and amyloid‐β peptide degradation

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The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases

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Biomarkers of Oxidative Damage and Inflammation in Alzheimer's Disease

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Control of Autophagic Cell Death by Caspase-10 in Multiple Myeloma

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Tumor Necrosis Factor α Is Toxic to Embryonic Mesencephalic Dopamine Neurons

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Regulation of apoptosis in health and disease: the balancing act of BCL-2 family proteins

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The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

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Elusive roles for reactive astrocytes in neurodegenerative diseases

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Programmed cell death in aging

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Presenilin 1 Maintains Lysosomal Ca2+ Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification

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Lysosome biology in autophagy

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Autophagic Dysfunction in Neurodegeneration

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The Pathological Mechanism of Neuronal Autophagy-Lysosome Dysfunction After Ischemic Stroke

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NEOSTRIATAL HUNTINGTIN IMMUNOREACTIVITY CORRELATES WITH VULNERABILITY TO NEURODEGENERATION IN HUNTINGTONʼS DISEASE

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Autophagy Flux: A Bottleneck in the Clearance of Damaged Organelles and Proteins after Skeletal Muscle Injury

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