Everyday executive function impairments predict comorbid psychopathology in autism spectrum and attention deficit hyperactivity disorders
Abstract
OBJECTIVE: Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) both have psychiatric comorbidities and distinctive profiles of executive dysfunction. Although there is evidence that executive function (EF) plays a role in the expression of specific behaviors and psychiatric symptoms, it is not known whether specific EF deficits in ASD and ADHD may be pathways to comorbidities in the disorders. This study examines whether parent reported problems with flexibility in ASD and inhibition in ADHD mediate the disorders' associations with anxiety/depression and oppositional/aggressive behavior, respectively. METHOD: Parent report data from the Behavior Rating Inventory of Executive Function (BRIEF) and the Child Behavior Checklist (CBCL) were obtained for 125 children (70 ASD, 55 ADHD Hyperactive/Impulsive or Combined type) as part of a neuropsychological assessment. Diagnostic status, BRIEF Shift (shifting/flexibility) and Inhibit (behavioral inhibition) scale scores, and CBCL Anxious/Depressed (anxiety/depression) and Aggressive Behavior (oppositionality/aggression) scale scores were analyzed with a path analysis to investigate the relation of flexibility and inhibition to comorbid symptoms in children with ASD and ADHD. RESULTS: In a path model with good fit ASD predicted greater inflexibility which predicted greater anxiety/depression, while ADHD predicted greater disinhibition that predicted greater aggression, consistent with our mediational hypotheses. Unexpectedly, the greater inflexibility associated with ASD also predicted greater aggression. CONCLUSIONS: Findings support the importance of everyday EF problems in ASD and ADHD as predictors of comorbid psychopathology and as crucial intervention targets for potential prevention and mitigation of comorbid symptoms.
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Set-shifting and inhibition predicted internalizing and externalizing psychopathology in ASD and ADHD.
“set-shifting and inhibition predicted internalizing and externalizing psychopathology in ASD and ADHD (Lawson et al., 2015).”
From Data‐driven identification of subtypes of executive function across typical development, attention deficit hyperactivity disorder, and autism spectrum disorders (2020) · cites this paper as Lawson et al., 2015
Difficulties with habituation and flexibility, associated with disrupted integration between mPFC and limbic regions, can be treated directly with benefits for anxiety and depression.
“Difficulties with habituation and flexibility, associated with disrupted integration between mPFC and limbic regions, can also be treated directly with benefits for anxiety and depression (Kenworthy et al., 2014; Lawson et al., 2015; Wallace et al., 2016).”
From Sensory, emotional and cognitive contributions to anxiety in autism spectrum disorders (2017) · cites this paper as Lawson et al., 2015
CI has been associated with self- and parent-reported depression in autistic individuals in several studies.
“as several studies have found CI to be associated with self and parent-reported depression in autistic individuals (Gabrys et al., 2018; Hollocks et al., 2014, 2022a, 2022b; Lawson et al., 2015).”
From Investigating the Effects of Transdiagnostic Processes on Anxiety and Depression Symptoms in Autistic Young People: the Mediating Role of Emotion Dysregulation. (2025) · cites this paper as Lawson et al., 2015
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“As described earlier, distinct behavioral issues can co-occur and even predict the opposite one in the same child; this does not only work for MDD but also for ASD which is often accompanied by greater aggression.(78) Given the complexity of mental problems, the associations of Phascolarctobacterium and Alistipes with…”
BackgroundHollocks, M. J., Charman, T., Baird, G., Lord, C., Pickles, A. R., & Simonoff, E. A. (2021) · Autism · doi:10.1177/13623613211046160 · Cited by 51 · see citing works
“…emotional and behavioural difficulties experienced by autistic people is supported by a limited literature showing similar associations in children, adolescents, and young adults both with (Visser et al., 2015) and without (Lawson et al., 2015; Wallace et al., 2016) mild intellectual disability.”
BackgroundResultBurrows, C. A., Timpano, K. R., & Uddin, L. Q. (2017) · Clinical Psychological Science · doi:10.1177/2167702616683506 · Cited by 43 · see citing works
“Specifically, cognitive inflexibility, and insistence on sameness have also been associated with elevated internalizing problems in ASD (Hollocks et al., 2014; Lawson et al., 2015; Rodgers, Glod, Connolly, & McConachie, 2012).”
BackgroundAssessment and Treatment of Executive Function Impairments in Autism Spectrum Disorder
Wallace, G. L., Yerys, B. E., Peng, C. S., Dlugi, E., Anthony, L. G., & Kenworthy, L. E. (2016) · International review of research in developmental disabilities · doi:10.1016/bs.irrdd.2016.07.004 · Cited by 45 · see citing works
Self-citationEmotion regulation and executive function: Associations with depression and anxiety in autism
Conner, C. M., Elias, R., Smith, I. C., & White, S. W. (2023) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2023.102103 · Cited by 43 · see citing works
Huang, F., Sun, L., Qian, Y., Liu, L., Ma, Q., Yang, L., Cheng, J. R., Cao, Q., Su, Y., Gao, Q., et al. (2016) · Chinese Medical Journal · doi:10.4103/0366-6999.187861 · Cited by 40 · see citing works
“[30] However, the importance of everyday EF problems in ADHD was emphasized since they were predictors of comorbid psychopathology[31]”
BackgroundKenworthy, L. E., Verbalis, A. D., Bascom, J., daVanport, S., Strang, J. F., Pugliese, C. E., Freeman, A. J., Jeppsen, C., Armour, A. C., Jost, G. M., et al. (2021) · Autism · doi:10.1177/13623613211029117 · Cited by 40 · see citing works
“, 2015) and in autistic people in particular (Hollocks et al., 2014; Lawson et al., 2015; Wallace et al., 2016; Zimmerman et al., 2017).”
BackgroundSelf-citationLei, J., Charman, T., Leigh, E., Russell, A., Mohamed, Z., & Hollocks, M. J. (2022) · Autism Research · doi:10.1002/aur.2826 · Cited by 35 · see citing works
“Overall, many studies found that the parent/teacher reported CI significantly correlated with greater symptoms of anxiety (Dieckhaus et al., 2021; Lawson et al., 2015; Uljarevi c et al., 2022; Vogan et al., 2018), depression (Gardiner & Iarocci, 2018; Lawson et al., 2015; Lieb & Bohnert, 2017) and…”
BackgroundInfluentialGaining Insights into Aggressive Behaviour in Autism Spectrum Disorder Using Latent Profile Analysis
Sullivan, M. O., Gallagher, L., & Heron, E. A. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-04129-3 · Cited by 36 · see citing works
Kalb, L. G., Vasa, R. A., Ballard, E. D., Woods, S. W., Goldstein, M. A., & Wilcox, H. C. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2820-7 · Cited by 36 · see citing works
“Other challenges faced by children with ASD include elopement, sensory processing and executive function difficulties, and lack of danger perception (Cavalari and Romanczyk 2012; Anderson et al. 2012; Lawson et al. 2015; Iannuzzi et al. 2014).”
BackgroundTakara, K., & Kondo, T. (2015) · Mental Health in Family Medicine · doi:10.25149/1756-8358.1102011 · Cited by 35 · see citing works
“Various backgrounds should be taken into consideration when treating depressed adults with ASD, such as past negative experiences bullying [14,88], interpersonal friction [14, 16, 21, 89], and school maladjustment [14, 90]), psychological vulnerability (loneliness [89, 91], lowered self-esteem [87, 91 92], poor emotio…”
BackgroundMaternal Urinary Fluoride and Child Neurobehavior at Age 36 Months
Malin, A. J., Eckel, S. P., Hu, H., Martinez-Mier, E. A., Hernandez‐Castro, I., Yang, T., Farzan, S. F., Habre, R., Breton, C. V., & Bastain, T. M. (2024) · JAMA Network Open · doi:10.1001/jamanetworkopen.2024.11987 · Cited by 34 · see citing works
Dimakos, J., Gauthier-Gagné, G., Lin, L., Scholes, S., & Gruber, R. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.08.001 · Cited by 33 · see citing works
Temperament and Self‐Regulation
Galehouse, P. J., & Foley, M. (2012) · Wiley eBooks · doi:10.1002/9781118704660.ch2 · Cited by 37 · see citing works
Sáez-Suanes, G. P., García-Villamisar, D., del Pozo Armentia, A., & Dattilo, J. (2020) · Research in Developmental Disabilities · doi:10.1016/j.ridd.2020.103784 · Cited by 33 · see citing works
Effects of therapeutic recreation on adults with ASD and ID: a preliminary randomized control trial
García-Villamisar, D. A., Dattilo, J., & Muela, C. (2016) · Journal of Intellectual Disability Research · doi:10.1111/jir.12320 · Cited by 36 · see citing works
Ameis, S. H., Haltigan, J. D., Lyon, R. E., Sawyer, A., Mirenda, P., Kerns, C. M., Smith, I. M., Vaillancourt, T., Volden, J., Waddell, C., et al. (2021) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13493 · Cited by 37 · see citing works
“BRIEF-measured set-shifting has also been found to mediate the relation between ASD (vs. ADHD) diagnostic status and anxious/depressed behaviors in a cross-sectional study of children and youth (Lawson et al., 2015).”
BackgroundMethodResultInfluentialReal-world executive functioning for autistic children in school and home settings
Tschida, J. E., & Yerys, B. E. (2021) · Autism · doi:10.1177/13623613211041189 · Cited by 32 · see citing works
Hocking, D. R., Reeve, J. L., & Porter, M. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0137628 · Cited by 31 · see citing works
Hawco, C. S., Yoganathan, L., Voineskos, A. N., Lyon, R. E., Tan, T., Daskalakis, Z. J., Blumberger, D. M., Croarkin, P. E., Lai, M., Szatmári, P., et al. (2020) · NeuroImage Clinical · doi:10.1016/j.nicl.2020.102260 · Cited by 30 · see citing works
“, 2008), are associated with mental health symptoms (Lawson et al., 2015), adaptive functioning (Bertollo and Yerys, 2019; Gilotty et al.”
van Eijndhoven, P., Collard, R. M., Vrijsen, J. N., Geurts, D. E. M., Vásquez, A. A., Schellekens, A., van den Munckhof, E., Brolsma, S. C. A., Duyser, F. A., Bergman, M. A., et al. (2021) · JMIRx Med · doi:10.2196/31269 · Cited by 34 · see citing works
“In individuals with ASD, there is some evidence that poorer executive functioning (and greater behavioral inflexibility) predicts greater anxiety and depression [48,65].”
BackgroundMild-to-Moderate Gestational Iodine Deficiency Processing Disorder
Hay, I., Hynes, K., & Burgess, J. R. (2019) · Nutrients · doi:10.3390/nu11091974 · Cited by 30 · see citing works
“These executive function processing difficulties are also linked to working memory capacity difficulties with individuals with ASD having slower reaction time and a higher rate of perseveration when responding to questions [84].”
BackgroundKenworthy, L. E., Childress, D., Armour, A. C., Verbalis, A. D., Zhang, A., Troxel, M., Handsman, R., Kocher, K., Myrick, Y., Werner, M. A., et al. (2022) · Autism · doi:10.1177/13623613221111212 · Cited by 30 · see citing works
“It also drives negative child outcomes that put extra strain on parents, such as poor adaptive skills (Pugliese et al., 2016), and co-occurring psychopathology (Lawson et al., 2015).”
BackgroundSelf-citationMaddox, B. B., Cleary, P., Kuschner, E. S., Miller, J. S., Armour, A. C., Guy, L., Kenworthy, L. E., Schultz, R. T., & Yerys, B. E. (2017) · Autism · doi:10.1177/1362361317712651 · Cited by 30 · see citing works
“This study demonstrates that impairments in emotion regulation and executive function may particularly contribute to challenging behaviors in school-age children with ASD without ID, which is consistent with recent research (Lawson et al., 2015; Patel et al., 2016; Samson et al., 2015).”
BackgroundResultSelf-citationLeno, V. C., Vitoratou, S., Kent, R. G., Charman, T., Chandler, S., Jones, C. R. G., Happe, F. G. E., Baird, G., Pickles, A. R., & Simonoff, E. A. (2018) · Autism · doi:10.1177/1362361318769176 · Cited by 27 · see citing works
“Correspondingly, aggressive behaviour in children with ASD is associated with parent-143 reported inattention and hyperactivity (Hill et al., 2014) and inflexibility (Lawson et al., 2015; Visser et al., 2014).”
BackgroundRothärmel, M., Moulier, V., Vasse, M., Isaac, C., Faerber, M., Bendib, B., Miréa-Grivel, I., Opolczynski, G., Rosier, A., & Guillin, O. (2019) · Neuropsychobiology · doi:10.1159/000501025 · Cited by 27 · see citing works
Executive Function in Autism: Association with ADHD and ASD Symptoms
Lee, R. R., Ward, A. R., Lane, D. M., Aman, M. G., Loveland, K. A., Mansour, R., & Pearson, D. A. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04852-2 · Cited by 30 · see citing works
Hilton, C. L. (2015) · International Journal of Sports and Exercise Medicine · doi:10.23937/2469-5718/1510017 · Cited by 26 · see citing works
“Findings from a study of 70 children and adolescents between age 6 and 16 years diagnosed with ASD by Lawson and associates [34] indicate EF problems as a predictor of comorbid psychopathology (anxiety/depression and aggression/oppositionality) and as crucial intervention targets for potential prevention and mitigatio…”
BackgroundAtypical core-periphery brain dynamics in autism
Roy, D., & Uddin, L. Q. (2021) · Network Neuroscience · doi:10.1162/netn_a_00181 · Cited by 22 · see citing works
“Interestingly, both cross-sectional and longitudinal data support the increased segregation-with-maturation and decrease thereafter story (Baum et al., 2017; Dajani et al., 2020; Huang et al., 2015; Keown et al., 2017; Lawson et al., 2015).”
BackgroundCremone‐Caira, A., Trier, K. A., Sanchez, V., Kohn, B. H., Gilbert, R. K., & Faja, S. (2020) · Autism · doi:10.1177/1362361320955107 · Cited by 24 · see citing works
“The domains of EF affected among individuals with developmental disorders vary: relative to typically developing (TD) children, children with ASD often have difficulty with set-shifting abilities, whereas working memory and inhibition are characteristically impaired among children with ADHD (Antshel et al., 2016; Geur…”
BackgroundInfluentialTesfaye, R., Wright, N., Zaidman‐Zait, A., Bedford, R., Zwaigenbaum, L., Kerns, C. M., Duku, E., Mirenda, P., Bennett, T. A., Georgiades, S., et al. (2021) · SLEEP · doi:10.1093/sleep/zsab122 · Cited by 23 · see citing works
Orm, S., Øie, M. G., Fossum, I. N., Andersen, P. N., & Skogli, E. W. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.724759 · Cited by 23 · see citing works
Zukerman, G., Yahav, G., & Ben‐Itzchak, E. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04632-y · Cited by 22 · see citing works
Environmental influences on development of executive functions in dogs
Foraita, M., Howell, T. J., & Bennett, P. C. (2021) · Animal Cognition · doi:10.1007/s10071-021-01489-1 · Cited by 21 · see citing works
Distinct Frontoparietal Brain Dynamics Underlying the Co-Occurrence of Autism and ADHD
Watanabe, D., & Watanabe, T. (2023) · eNeuro · doi:10.1523/eneuro.0146-23.2023 · Cited by 23 · see citing works
“We can find face validation for this assumption in other prior findings that (1) pure ADHD children had more flexible and unstable cognition compared with TD (Kuntsi and Klein, 2011) and pure ASD individuals (Ozonoff and Jensen, 1999; Sergeant et al., 2002; Corbett et al., 2009; Lawson et al., 2015) and (2) the RRB sc…”
ResultAutonomic and Electrophysiological Evidence for Reduced Auditory Habituation in Autism
Gandhi, T. K., Tsourides, K., Singhal, N., Cardinaux, A. L., Jamal, W., Pantazis, D., Kjelgaard, M., & Sinha, P. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04636-8 · Cited by 19 · see citing works
Wan, B., Wang, Z., Jung, M., Lu, Y., He, H., Chen, Q., & Yu, J. Z. (2019) · Autism Research · doi:10.1002/aur.2120 · Cited by 18 · see citing works
“, 2013] and executive dysfunction [Demetriou et al., 2018; Gardiner & Iarocci, 2018; Lawson et al., 2015; Wallace et al., 2016], both of which have been associated with brain alterations.”
BackgroundDickson, K. S., Aarons, G. A., Anthony, L. G., Kenworthy, L. E., Crandal, B. R., Williams, K. N., & Brookman-Frazee, L. I. (2020) · Pilot and Feasibility Studies · doi:10.1186/s40814-020-00593-2 · Cited by 18 · see citing works
Self-citationTemperament and Self‐Regulation
Galehouse, P. J., & Foley, M. (2021) · doi:10.1002/9781119487593.ch2 · Cited by 18 · see citing works
Anning, K. L., Langley, K., Hobson, C., & Van Goozen, S. H. M. (2023) · Cortex · doi:10.1016/j.cortex.2023.06.005 · Cited by 18 · see citing works
“Research has also found that comorbid anxiety may mitigate some EF problems by increasing cortical arousal and alertness (Arnsten, 2009), but can worsen performance on more complex EF tasks (e.g., Castagna et al., 2019; Lawson et al., 2015).”
Costescu, C. A., Roșan, A., David, C., Cozma, L., & Calota, A. (2023) · European Journal of Investigation in Health Psychology and Education · doi:10.3390/ejihpe13120194 · Cited by 17 · see citing works
Flynn, R. M., Colon-Acosta, N., Zhou, J., & Bower, J. D. (2019) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-019-03881-w · Cited by 17 · see citing works
“Previous research has supported that early diagnosis and intervention with cognitive training or cognitivebehavioral therapy for children with these disorders can result in higher quality of life (Anderson-Hanley et al. 2011; Diamond and Liang 2016; Frazier et al. 2007; Lawson et al. 2015; Miyake et al. 2000; Zelazo e…”
BackgroundBergman, M. A., Schene, A. H., Vissers, C., Vrijsen, J. N., Kan, C. C., & van Oostrom, I. (2019) · Research in Autism · doi:10.1016/j.rasd.2019.101455 · Cited by 17 · see citing works
Liu, C., Liu, R., Tao, R., Feng, J., Liang, X., Yang, Y., & Sit, C. H. P. (2025) · Preventive Medicine · doi:10.1016/j.ypmed.2025.108246 · Cited by 16 · see citing works
Kenny, L., Remington, A., & Pellicano, E. (2024) · Autism · doi:10.1177/13623613231224093 · Cited by 17 · see citing works
“This is despite EF challenges regularly being reported in questionnaire measures of real-world EF (e.g. Kenworthy et al., 2005; R. A. Lawson et al., 2015), and regularly described by autistic people (Cribb et al., 2019; DePape & Lindsay, 2016; Livingston et al., 2019; Pellicano et al., 2021).”
BackgroundSmith, T. F., Kaczorowski, J. A., & Acosta, M. T. (2020) · Child s Nervous System · doi:10.1007/s00381-020-04745-w · Cited by 14 · see citing works
“Difficulty with cognitive flexibility is also observed in NF1-related comorbidities, like ASD [95, 96] and anxiety [97, 98].”
BackgroundAnxiety relates to classroom executive function problems in students with ASD, but not ADHD
Dieckhaus, M. F. S., Hardy, K. K., Anthony, L. G., Verbalis, A. D., Kenworthy, L. E., & Pugliese, C. E. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101739 · Cited by 14 · see citing works
Self-citationFitzgerald, B., McCusker, C., Dempsey, M., & Galvin, A. D. (2023) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-023-00385-3 · Cited by 14 · see citing works
Vaidya, C. J., & Klein, C. (2022) · Current topics in behavioral neurosciences · doi:10.1007/7854_2022_334 · Cited by 13 · see citing works
Lupi, E., Tucci, F., Casula, L., Novello, R. L., Guerrera, S., Vicari, S., & Valeri, G. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1092164 · Cited by 16 · see citing works
“, 2014) and emotional and behavioral problems over time (Hollocks et al., 2014; Lawson et al., 2015).”
BackgroundDevelopment and Psychometric Evaluation of the Open-Source Challenging Behavior Scale (OS-CBS)
Frazier, T. W., Khaliq, I. N., Scullin, K. M., Uljarević, M., Shih, A. J., & Karpur, A. (2022) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-022-05750-5 · Cited by 13 · see citing works
“For the present study, the general executive composite raw score was expected to show a moderate association with the OS-CBS total score (.30 > r > .50), as poor executive function may contribute to psychopathology and challenging behavior (Lawson et al., 2015).”
Barnes, G. L., Ozsivadjian, A., Baird, G., Absoud, M., & Hollocks, M. J. (2025) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06246-0 · Cited by 12 · see citing works
Neural Correlates of Executive Functioning in Anorexia Nervosa and Obsessive–Compulsive Disorder
Thomas, K. S., Birch, R. E., Jones, C. R. G., & Vanderwert, R. E. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.841633 · Cited by 12 · see citing works
“with a neurodevelopmental condition, such as autism spectrum disorder (ASD) or attention deficit hyperactivity disorder (ADHD), may represent a clear “at-risk” group for the development of AN and OCD, as studies commonly report executive functioning impairments in these samples (e.g., Ozonoff and Jensen, 1999; Lawson…”
BackgroundGodoy, P. B. G., Shephard, E., Milosavljevic, B., Johnson, M. H., Charman, T., The BASIS Team, Baron‐Cohen, S., Bedford, R., Bolton, P., Chandler, S., et al. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04732-9 · Cited by 12 · see citing works
Wong, O. W. H., Barzilay, R., Lam, A. M. W., Chan, S. S. M., Calkins, M. E., Gur, R. E., & Gur, R. C. (2022) · Psychological Medicine · doi:10.1017/s0033291722001787 · Cited by 13 · see citing works
“Studies have demonstrated that executive dysfunction in ASD could be related to psychopathology such as anxiety (Hollocks et al., 2014), depressive disorders (Wallace et al., 2016), aggressive behaviors (Lawson et al., 2015), and ADHD (Craig et al., 2016).”
BackgroundDoyle, L. R., Glass, L., Wozniak, J. R., Kable, J. A., Riley, E. P., Coles, C. D., Sowell, E. R., Jones, K. L., Mattson, S. N., & CIFASD, T. (2019) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.14036 · Cited by 12 · see citing works
Ng, R., Bjornsson, H. T., Fahrner, J. A., & Harris, J. R. (2023) · Archives of Clinical Neuropsychology · doi:10.1093/arclin/acad060 · Cited by 11 · see citing works
Fossum, I. N., Orm, S., Andersen, P. N., Geurts, H. M., Øie, M. G., & Skogli, E. W. (2023) · Developmental Neuropsychology · doi:10.1080/87565641.2023.2206663 · Cited by 12 · see citing works
“EF difficulties are one potential mechanism underlying the development and maintenance of co-occurring symptoms among individuals with ASD (Andersen et al., 2017; R. A. Lawson et al., 2015).”
BackgroundFlynn, R. M., & Colon-Acosta, N. (2016) · Games for Health Journal · doi:10.1089/g4h.2016.0053 · Cited by 11 · see citing works
Skogli, E. W., Andersen, P. N., Orm, S., Hovik, K. T., & Øie, M. G. (2022) · International Journal of Disability Development and Education · doi:10.1080/1034912x.2022.2095360 · Cited by 10 · see citing works
“…to typically developing children (TDC) (Gioia, Isquith, Kenworthy, & Barton, 2002; Hovik et al., 2017; Kouklari, Tsermentseli, & Monks, 2018; Lawson et al., 2015; Mahone et al., 2002; Rosenthal et al., 2013; Semrud-Clikeman, Walkowiak, Wilkinson, & Butcher, 2010; Sergeant, Geurts, &…”
“The Videos Made Me Feel Less Alone”: Feasible Executive Function Supports For Families
Smith, J. V., Dahlman, T., Holmes, J., Armour, C. A., Verbalis, A. D., Ratto, A. B., Hardy, K. K., Gunn, M., Decker, K., Brown, D., et al. (2024) · Journal of Child and Family Studies · doi:10.1007/s10826-023-02768-w · Cited by 9 · see citing works
“EF challenges predict lower quality of life (de Vries & Geurts, 2015, Snyder et al., 2015), co-occurring psychiatric conditions or symptoms (Lawson et al., 2015; Wallace et al. 2016), and poorer adaptive functioning (Pugliese et al., 2014, 2016).”
Self-citationDickson, K. S., Galligan, M. R. L., Holt, T., Kenworthy, L. E., Anthony, L. G., Roesch, S. C., & Brookman-Frazee, L. I. (2024) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06365-8 · Cited by 10 · see citing works
“Executive dysfunction is related to concurrent and enduring negative outcomes, including increased co-occurring mental health symptoms in autistic children (Lawson et al., 2015; Pugliese et al., 2020).”
Self-citationHollocks, M. J., McQuaid, G. A., Yerys, B. E., Strang, J. F., Anthony, L. G., Kenworthy, L. E., Lee, N., & Wallace, G. L. (2023) · Autism Research · doi:10.1002/aur.3025 · Cited by 10 · see citing works
“…cognitive flexibility are a common experience for autistic people and have been associated with a range of difficulties including reduced adaptive skills (Bertollo et al., 2020) and greater emotional and behavioral challenges (Hollocks et al., 2021; Lawson et al., 2015; Ozsivadjian et al., 2021).”
Self-citationSchippers, E. E., Hoogsteder, L. M., & Stams, G. J. J. M. (2020) · Journal of Forensic Sciences · doi:10.1111/1556-4029.14539 · Cited by 9 · see citing works
“lem behaviors, since not only aggression, but many psychiatric problems relate to poor EF (21,22).”
BackgroundBerenguer, C., Miranda, B. R., & Leader, G. (2018) · Journal of Educational and Developmental Psychology · doi:10.5539/jedp.v8n2p107 · Cited by 9 · see citing works
“Flexibility involves transitioning from one thought to another, shifting successfully from one task to another, and using flexible problem solving in a variety of contexts (Lawson et al., 2015).”
BackgroundPugliese, C. E., Handsman, R., You, X., Anthony, L. G., Vaidya, C. J., & Kenworthy, L. E. (2024) · Autism · doi:10.1177/13623613241246091 · Cited by 8 · see citing works
“Specifically, we expect an EF profile characterized by inflexibility will be uniquely associated with anxiety, depression, and aggression (e.g. Hollocks et al., 2014; Lawson et al., 2015).”
Self-citationCapp, S., Burca, A. D., Aydın, Ü., Agnew‐Blais, J. C., Lautarescu, A., Ronald, A., Happe, F. G. E., & McLoughlin, G. (2025) · JCPP Advances · doi:10.1002/jcv2.70003 · Cited by 9 · see citing works
“Better - informed interventions may also target executive function demands in early adulthood to mitigate their effects on mental health in individuals with high autistic or ADHD traits (Aydin et al., 2022; Lawson et al., 2015).”
Dickson, K. S., Kenworthy, L. E., Anthony, L. G., & Brookman-Frazee, L. I. (2022) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2021.2013142 · Cited by 7 · see citing works
“However, further work examining this possibility is needed, especially for additional mental health conditions beyond ASD and ADHD.”
BackgroundInfluentialSelf-citationRodgers, J., & South, M. (2020) · Journal of Child Psychology and Psychiatry · doi:10.1111/jcpp.13340 · Cited by 7 · see citing works
“There are a few studies linking cognitive inflexibility in autism to anxiety symptoms (Hol-locks, Howlin, Papadopoulos, Khondoker, & Simon-off, 2014) and externalising difficulties (Lawson et al., 2015).”
BackgroundChien, Y., Tai, Y., Chiu, Y., Tsai, W., & Gau, S. S. (2023) · Autism · doi:10.1177/13623613231184733 · Cited by 7 · see citing works
“Several studies have adopted the BRIEF to investigate everyday executive functions in autism (Blijd-Hoogewys et al., 2014; Gilotty et al., 2002; Gioia et al., 2002; Kenworthy et al., 2005; Lawson et al., 2015; Rosenthal et al., 2013; Smidts & Huizinga, 2009; van den Bergh et al., 2014).”
BackgroundBrookman-Frazee, L. I., Baker-Ericzén, M. J., Chan, J., Dickson, K. S., Rieth, S. R., Haine‐Schlagel, R., Stadnick, N. A., Stahmer, A. C., & Suhrheinrich, J. (2022) · Autism and child psychopathology series · doi:10.1007/978-3-030-88538-0_26 · Cited by 6 · see citing works
Do executive functions buffer against COVID-19 stress?
Ng, T. L. Y., Majeed, N. M., Lua, V. Y. Q., & Hartanto, A. (2023) · Current Psychology · doi:10.1007/s12144-023-04652-8 · Cited by 6 · see citing works
“For instance, greater proficiency in executive function tasks has been associated with better mental (Lawson et al., 2015 ; Paelecke-Habermann et al., 2005 ; Penadés et al., 2007) and physical health (Crescioni et al., 2011; Ng & Hartanto, 2022; Riggs et al., 2010 ), stronger social relationships…”
Nakua, H., Hawco, C. S., Forde, N. J., Jacobs, G. R., Joseph, M. J. E., Voineskos, A. N., Wheeler, A. L., Lai, M., Szatmári, P., Kelley, E. A., et al. (2022) · Brain Structure and Function · doi:10.1007/s00429-022-02483-0 · Cited by 6 · see citing works
Hamilton, A., Tallberg, P., Ilahi, F., Hoff, E. V., Ahmadi, B., & Daukantaité, D. (2024) · Child Neuropsychology · doi:10.1080/09297049.2024.2434736 · Cited by 5 · see citing works
“This study recognizes the utility of the Swedish translation of the BRIEF-2’s in assessing day-to-day behavioral manifestations of EF, while exploring differences between youth with NDDs (specifically ADHD and ASD) and those with non-NDD psychiatric comorbidities as well as community controls in terms of parent-rated…”
InfluentialRanjbar, F., Dadgar, H., Azizi, M., & Dalvand, H. (2024) · Advances in Autism · doi:10.1108/aia-06-2024-0040 · Cited by 5 · see citing works
Cid-Duarte, S., Departamento de Psicología, U. D. O. (., Areces, D., Departamento de Psicología, U. D. O. (., Núñez, J. C., & Departamento de Psicología, U. D. O. (. (2022) · Revista de Psicología y Educación - Journal of Psychology and Education · doi:10.23923/rpye2023.01.232 · Cited by 6 · see citing works
Narzisi, A., Barbetti, F., Fabbri‐Destro, M., Berloffa, S., Fantozzi, P., Viglione, V., Muccio, R., Valente, E., Accorinti, I., Foti, E., et al. (2026) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2026.1765698 · Cited by 4 · see citing works
“This dissociation may re fl ect a breakdown in the cognitive-emotional integration mechanisms that typically support adaptive functioning in neurodevelopmental populations (18, 40, 55).”
Hollocks, M. J., McQuaid, G. A., Lee, N., & Wallace, G. L. (2025) · Autism Research · doi:10.1002/aur.70061 · Cited by 4 · see citing works
“…lower levels of cognitive flexibility when compared to those without an autism diagnosis (Bertollo et al. 2020), and this has been associated directly with increased symptoms of both anxiety and depression (Hollocks et al. 2022; Lawson et al. 2015; Ozsivadjian et al. 2021; Wallace et al. 2016).”
Self-citation
- Authors
- Lawson, R. A., Papadakis, A. A., Higginson, C. I., Barnett, J. E., Wills, M. C., Strang, J. F., Wallace, G. L., & Kenworthy, L.
- Affiliations
- Loyola University Maryland (US)
- Children's National (US)
- George Washington University (US)
- ORCID
- Venue
- Neuropsychology
- Published
- 2015-05
- Volume
- 29
- Issue
- 3
- Pages
- 445-453
- ISSN
- 0894-4105 (ISSN-L)
- 1931-1559
- OpenAlex
- W2084269933
- Cited by
- 169
- References
- 68
- Citations by year
- 2026: 13 · 2025: 13 · 2024: 16 · 2023: 20 · 2022: 19 · 2021: 14 · 2020: 18 · 2019: 16 · 2018: 8 · 2017: 13 · 2016: 10 · 2015: 6 · 2012: 1
- FWCI
- 5.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Isadore and Bertha Gudelsky Foundation
- Frederick and Elizabeth Singer Foundation
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
- Social Sciences › Psychology › Neuropsychology and Physiological Psychology › Developmental and Educational Neuropsychology
- Keywords
- executive function, autism spectrum disorder, attention deficit hyperactivity disorder, psychiatric comorbidity, flexibility, behavioral inhibition, inflexibility, disinhibition, anxiety and depression, mediation, children
- MeSH terms
- Autism Spectrum Disorder, Adolescent, Attention Deficit Disorder with Hyperactivity, Mental Disorders, Child, Depression, Female, Humans, Inhibition, Psychological, Male, Models, Psychological, Neuropsychological Tests, Executive Function
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