The Association Between Social Cognition and Executive Functioning and Symptoms of Anxiety and Depression in Adolescents With Autism Spectrum Disorders
Abstract
While high levels of anxiety and depression are now recognized as major co‐occurring problems in children and young people with an autism spectrum disorder (ASD), research examining possible associations with individual differences in neurocognitive functioning has been limited. This study included 90 adolescents with an ASD aged 14–16 years with a full‐scale IQ > 50. Using structural equation modeling, we examined the independent relationships between multiple measures of executive functioning and social cognition on severity of anxiety or depressive symptoms. Results indicated a significant association between poorer executive functioning and higher levels of anxiety, but not depression. In contrast, social cognition ability was not associated with either anxiety or depression. This study is the first to report significant associations between executive functions and anxiety in ASD. This may suggest that poor executive functioning is one factor associated with the high prevalence of anxiety disorder in children and adolescents with ASD. Autism Res 2014, 7: 216–228. © 2014 I nternational S ociety for A utism R esearch, W iley P eriodicals, I nc.
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The finding of a large direct effect of IU on depression symptoms in autistic young people was in keeping with previous research.
“The finding of a large, direct effect of IU on depression symptoms in autistic young people was in keeping with previous research in this area (Cai et al., 2018; Hollocks et al., 2014).”
From Investigating the Effects of Transdiagnostic Processes on Anxiety and Depression Symptoms in Autistic Young People: the Mediating Role of Emotion Dysregulation. (2025) · cites this paper as Hollocks et al., 2014
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“The studies that did not report significant associations indicated that that social cognition problems did not predict symptoms of depression and that engagement in social activities did not predict internalizing symptoms longitudinally (Hollocks et al., 2014; Taylor et al., 2017).”
BackgroundMental health challenges faced by autistic people
Lai, M. (2023) · Nature Human Behaviour · doi:10.1038/s41562-023-01718-2 · Cited by 80 · see citing works
“Intellectual abilities also significantly influence executive function and social cognition 156 .”
BackgroundMagiati, I., Ong, C. W., Lim, X. Y., Tan, J. W., Ong, A. Y. L., Patrycia, F., Fung, D. S. S., Sung, M., Poon, K. K., & Howlin, P. (2015) · Autism · doi:10.1177/1362361315577519 · Cited by 73 · see citing works
“…either to total anxiety rates or SCAS-P specific anxiety subtypes when other child factors were controlled, parallels the results of Rieske et al. (2011) and Hollocks et al. (2014b), who found that social impairments and social cognition, respectively, were not associated with overall anxiety.”
BackgroundResultVogan, V. M., Leung, R. C., Safar, K., Martinussen, R., Smith, M. L., & Taylor, M. J. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.01774 · Cited by 72 · see citing works
“Previous studies of TD children and young adults have found strong associations between poor EF and externalizing and internalizing behaviors (Castaneda et al., 2008; Hughes and Ensor, 2008; Snyder, 2013).”
Andersen, P. N., Skogli, E. W., Hovik, K. T., Egeland, J., & Øie, M. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2415-8 · Cited by 63 · see citing works
Comparing stress and arousal systems in response to different social contexts in children with ASD
Corbett, B. A., Muscatello, R. A., & Baldinger, C. (2018) · Biological Psychology · doi:10.1016/j.biopsycho.2018.12.010 · Cited by 62 · see citing works
“This blunted response may be associated with comorbid symptoms such as social problems (Edmiston, Jones, & Corbett, 2016) or anxiety (Hollocks et al., 2014; Mikita et al., 2015).”
BackgroundUnderstanding, recognising and treating co-occurring anxiety in autism
Rodgers, J., & Ofield, A. (2018) · Current Developmental Disorders Reports · doi:10.1007/s40474-018-0132-7 · Cited by 62 · see citing works
The relationship between alexithymia and theory of mind: A systematic review
Pisani, S., Murphy, J., Conway, J. R., Millgate, E., Catmur, C., & Bird, G. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.09.036 · Cited by 63 · see citing works
Anxiety and intellectual functioning in autistic children: A systematic review and meta-analysis
Mingins, J., Tarver, J., Waite, J., Jones, C. A., & Surtees, A. D. R. (2020) · Autism · doi:10.1177/1362361320953253 · Cited by 55 · see citing works
“Of the analyses conducted, five used some form of regression and found no significant result, where IQ scores were not significant predictors of anxiety group membership (Gardiner & Iarocci, 2018; Hollocks et al., 2014b; Kerns et al., 2014; Rosenberg et al., 2011; Simonoff et al., 2008).”
MethodSelf-citationOakley, B. F. M., Loth, E., & Murphy, D. (2021) · International Review of Psychiatry · doi:10.1080/09540261.2021.1872506 · Cited by 59 · see citing works
Pallathra, A. A., Calkins, M. E., Parish‐Morris, J., Maddox, B. B., Perez, L. S., Miller, J. S., Gur, R. C., Mandell, D. S., Schultz, R. T., & Brodkin, E. S. (2018) · Autism Research · doi:10.1002/aur.1910 · Cited by 55 · see citing works
Schwartzman, J. M., & Corbett, B. A. (2020) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2020.101613 · Cited by 53 · see citing works
“…reliability and strength of agreement were significant between TD early adolescents and their parents in that study (Ozsivadjian, Hibberd, & Hollocks, 2014), which matched results from other studies of higher reliability and strength of agreement between raters in TD cohorts (e.g.,…”
BackgroundResultInfluentialHollocks, M. J., Charman, T., Baird, G., Lord, C., Pickles, A. R., & Simonoff, E. A. (2021) · Autism · doi:10.1177/13623613211046160 · Cited by 51 · see citing works
“Difficulties with executive functioning are common in autism (Demetriou et al., 2018) and have been shown to be related to having greater symptoms of both emotional (Hollocks et al., 2014) and behavioural difficulties (Carter Leno et al., 2019) in childhood and adolescence.”
BackgroundInfluentialSelf-citationSturrock, A., Chilton, H., Foy, K., Freed, J., & Adams, C. (2021) · Autism · doi:10.1177/13623613211002047 · Cited by 49 · see citing works
“Other factors such as social cognition and executive function will contribute to poorer functionality, social interrelations and emotional wellbeing (Bishop-Fitzpatrick et al., 2017; Hollocks et al., 2014).”
BackgroundBailey, J., & Baker, S. T. (2020) · Journal of Research in Special Educational Needs · doi:10.1111/1471-3802.12490 · Cited by 46 · see citing works
Burrows, C. A., Timpano, K. R., & Uddin, L. Q. (2017) · Clinical Psychological Science · doi:10.1177/2167702616683506 · Cited by 43 · see citing works
“Several recent studies support this model, identifying independent links between negative self-views, cognitive flexibility, and increased rates of anxiety and depression in children, adolescents, and adults with ASD (Boulter, Freeston, South, & Rodgers, 2013; Hollocks et al., 2014; Wallace et al., 2016; Williamson, C…”
BackgroundResultCharacteristic Executive Dysfunction for High‐Functioning Autism Sustained to Adulthood
Xie, R., Sun, X., Yang, L., & Guo, Y. (2020) · Autism Research · doi:10.1002/aur.2304 · Cited by 45 · see citing works
“Second, severity of ASD symptoms may affect EF performance as some previous studies suggested that executive performance worsens as the symptoms of ASD worsen [Hollocks et al., 2014].”
ResultLieb, R. W., & Bohnert, A. M. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3205-2 · Cited by 43 · see citing works
Behavioral improvements in a valproic acid rat model of autism following vitamin D supplementation
Du, L., Zhao, G., Duan, Z., & Li, F. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.03.003 · Cited by 42 · see citing works
Ambrose, K., Simpson, K., & Adams, D. (2021) · Clinical Psychology Review · doi:10.1016/j.cpr.2021.102086 · Cited by 41 · see citing works
Emotion regulation and executive function: Associations with depression and anxiety in autism
Conner, C. M., Elias, R., Smith, I. C., & White, S. W. (2023) · Research in Autism Spectrum Disorders · doi:10.1016/j.rasd.2023.102103 · Cited by 43 · see citing works
Kenworthy, L. E., Verbalis, A. D., Bascom, J., daVanport, S., Strang, J. F., Pugliese, C. E., Freeman, A. J., Jeppsen, C., Armour, A. C., Jost, G. M., et al. (2021) · Autism · doi:10.1177/13623613211029117 · Cited by 40 · see citing works
“, 2015) and in autistic people in particular (Hollocks et al., 2014; Lawson et al., 2015; Wallace et al., 2016; Zimmerman et al., 2017).”
BackgroundLei, J., Charman, T., Leigh, E., Russell, A., Mohamed, Z., & Hollocks, M. J. (2022) · Autism Research · doi:10.1002/aur.2826 · Cited by 35 · see citing works
“…et al., 2022), Trail Making (Hollocks et al., 2022), Color Word Interference Task (CW-4; Andersen et al., 2015), Wisconsin Card Sorting Task (WCST; Hollocks et al., 2014, 2022; Tachibana et al., 2013; Teunisse et al., 2012), and the Cambridge Neuropsychological Test Automated battery Intra/Extra…”
BackgroundSelf-citationAnxiety in Autism Spectrum Disorder
Uljarević, M., Nuske, H. J., & Vivanti, G. (2016) · Springer eBooks · doi:10.1007/978-3-319-29695-1_2 · Cited by 36 · see citing works
Kuzminskaite, E., Begeer, S., Hoekstra, R. A., & Grove, R. (2020) · Autism · doi:10.1177/1362361320934218 · Cited by 33 · see citing works
“This is consistent with previous research reporting a significant link between autistic social traits and social anxiety (Spain et al., 2018), while no association with broader anxiety symptoms (Hollocks et al., 2014).”
BackgroundResultBen‐Itzchak, E., Koller, J., & Zachor, D. A. (2020) · Research on Child and Adolescent Psychopathology · doi:10.1007/s10802-020-00673-0 · Cited by 32 · see citing works
Wichers, R., van der Wouw, L. C., Brouwer, M. E., Lok, A., & Bockting, C. (2022) · Psychological Medicine · doi:10.1017/s0033291722003415 · Cited by 32 · see citing works
“, 2015) as well as poorer executive functioning (Hollocks et al., 2014) have been related to greater levels of anxiety.”
Backgroundvan Eijndhoven, P., Collard, R. M., Vrijsen, J. N., Geurts, D. E. M., Vásquez, A. A., Schellekens, A., van den Munckhof, E., Brolsma, S. C. A., Duyser, F. A., Bergman, M. A., et al. (2021) · JMIRx Med · doi:10.2196/31269 · Cited by 34 · see citing works
“In individuals with ASD, there is some evidence that poorer executive functioning (and greater behavioral inflexibility) predicts greater anxiety and depression [48,65].”
BackgroundAnxiety in youth with autism spectrum disorders: implications for treatment
Johnco, C. J., & Storch, E. A. (2015) · Expert Review of Neurotherapeutics · doi:10.1586/14737175.2015.1111762 · Cited by 32 · see citing works
“One of the outstanding treatment-related questions is whether or not ASD-specific treatments are necessary for the treatment of anxiety in youth with ASD.”
BackgroundInfluentialHirosawa, T., Kontani, K., Fukai, M., Kameya, M., Soma, D., Hino, S., Kitamura, T., Hasegawa, C., An, K., Takahashi, T., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0235380 · Cited by 28 · see citing works
Leno, V. C., Vitoratou, S., Kent, R. G., Charman, T., Chandler, S., Jones, C. R. G., Happe, F. G. E., Baird, G., Pickles, A. R., & Simonoff, E. A. (2018) · Autism · doi:10.1177/1362361318769176 · Cited by 27 · see citing works
“Data from the majority of the EF tasks, along with ToM tasks, have previously been reported in the SNAP cohort (Carter Leno et al., 2015; Hollocks et al., 2014).”
ResultSelf-citationMertens, J. B., Zane, E. R., Neumeyer, K., & Grossman, R. B. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2979-y · Cited by 28 · see citing works
Moradi, H., Sohrabi, M., Taheri, H., Khodashenas, E., & Movahedi, A. (2018) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2018.02.005 · Cited by 26 · see citing works
Menezes, M., Robinson, L. A., Román, M. J. S., & Cook, B. L. (2018) · Review Journal of Autism and Developmental Disorders · doi:10.1007/s40489-018-0146-4 · Cited by 26 · see citing works
Hilton, C. L. (2015) · International Journal of Sports and Exercise Medicine · doi:10.23937/2469-5718/1510017 · Cited by 26 · see citing works
“Hollocks and associates [33] examined 90 adolescents with ASD between 14 and 16 years of age and found a significant association between poorer executive functioning and higher levels of anxiety.”
Uljarević, M., Hedley, D., Nevill, R. E. A., Evans, D. W., Cai, R. Y., Butter, E. M., & Mulick, J. A. (2018) · Autism Research · doi:10.1002/aur.1953 · Cited by 25 · see citing works
“…affect severity scores, are inconsistent with previous studies reporting a positive association between impairments in the cognitive and emotional aspects of self-regulation and core ASD symptom severity [Berkovits et al., 2017; Hollocks et al., 2014; Samson et al., 2014; Uljarević et al., 2017].”
InfluentialMcArthur, G. E., Lee, E., & Laycock, R. (2022) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-022-05742-5 · Cited by 24 · see citing works
“Such anxiety was shown to predict poor executive functions in adolescents with ASD (Hollocks et al., 2014).”
BackgroundAntezana, L., Mosner, M. G., Troiani, V., & Yerys, B. E. (2015) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-015-2661-9 · Cited by 25 · see citing works
“There is now an appreciation for co-occurring anxiety and ADHD symptoms influencing performance on attention, executive function, and social processing tasks in youth with ASD (Corbett et al. 2009; Herrington et al., submitted; Hollocks et al. 2014; Pugliese et al. 2015; Sinzig et al. 2008; Yerys et al. 2013).”
BackgroundAdams, D., Ambrose, K., Simpson, K., Malone, S. A., & Dargue, N. (2023) · Clinical Child and Family Psychology Review · doi:10.1007/s10567-023-00450-7 · Cited by 23 · see citing works
Capriola, N. N., Maddox, B., & White, S. (2016) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-016-2827-0 · Cited by 33 · see citing works
Guo, Q., Yin, X., Qiao, M., Jia, Y., Chen, D., Shao, J., LeBaron, T. W., Gao, Y., Shi, H., & Jia, B. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00170 · Cited by 23 · see citing works
Teh, E. J., Chan, D. M.-E., Tan, G. K. J., & Magiati, I. (2017) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-017-3136-y · Cited by 22 · see citing works
Pagni, B. A., Hill, E., Walsh, M. J. M., Delaney, S., Ogbeama, D., Monahan, L., Cook, J. R., Guerithault, N., Dixon, M. V., Ballard, L., et al. (2023) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.220159 · Cited by 20 · see citing works
“5 Moreover, deficits in executive functioning — critical to managing mood and anxiety 6 — remain impaired across the lifespan of individuals with ASD.”
BackgroundDepression in young autistic people: A scoping review
Kim, S. Y., & Lecavalier, L. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101841 · Cited by 20 · see citing works
Mukherjee, S., & Beresford, B. (2023) · Autism · doi:10.1177/13623613231158959 · Cited by 14 · see citing works
“…processing skills; alexithymia), other child-centred factors (e.g. adaptive functioning skills) and socio-environmental factors (Carter Leno et al., 2018; Chandler et al., 2016; Colvert et al., 2021; Hollocks et al., 2014; Lundström et al., 2011; McCauley et al., 2020; Milosavljevic et al., 2016).”
BackgroundWang, J., Zheng, B., Zhou, D., Xing, J., Li, H., Li, J., Zhang, Z., Zhang, B., & Li, P. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.552345 · Cited by 19 · see citing works
“The autism spectrum disorder (ASD), a type of developmental neurobiological disorders, is characterized by the pervasive impairments of social interaction and communication capabilities, and the restricted, repetitive, and stereotyped behaviors, activities, and interests (1).”
BackgroundDickson, K. S., Aarons, G. A., Anthony, L. G., Kenworthy, L. E., Crandal, B. R., Williams, K. N., & Brookman-Frazee, L. I. (2020) · Pilot and Feasibility Studies · doi:10.1186/s40814-020-00593-2 · Cited by 18 · see citing works
Demetriou, E. A., Park, S. H., Pepper, K. L., Naismith, S. L., Song, Y. J., Thomas, E. E., Hickie, I. B., & Guastella, A. J. (2021) · Journal of Affective Disorders · doi:10.1016/j.jad.2020.11.089 · Cited by 17 · see citing works
Costescu, C. A., Roșan, A., David, C., Cozma, L., & Calota, A. (2023) · European Journal of Investigation in Health Psychology and Education · doi:10.3390/ejihpe13120194 · Cited by 17 · see citing works
“Hollocks et al. [26] investigated the association between executive functioning and anxiety and depression in adolescents with ASD aged between 14 and 16 years.”
BackgroundDell’Osso, L., Nardi, B., Bonelli, C., Amatori, G., Pereyra, M. A., Massimetti, E., Cremone, I. M., Pini, S., & Carpita, B. (2024) · Brain Sciences · doi:10.3390/brainsci14010064 · Cited by 18 · see citing works
“Similarly, people with ASD show greater cognitive inflexibility compared to the general population, and those difficulties with executive functioning appear to be correlated with greater symptoms of both emotional and behavioral difficulties [88–91].”
BackgroundBergman, M. A., Schene, A. H., Vissers, C., Vrijsen, J. N., Kan, C. C., & van Oostrom, I. (2019) · Research in Autism · doi:10.1016/j.rasd.2019.101455 · Cited by 17 · see citing works
Development and validation of the Executive Functioning Scale
Uljarević, M., Cai, R. Y., Hardan, A. Y., & Frazier, T. W. (2023) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.1078211 · Cited by 17 · see citing works
“Further, EF and ER difficulties are associated with specific symptom domains commonly observed across NDD/NPD, including anxiety (16, 26), sameness/rituals (27, 28), social functioning difficulties (29, 30), positive and negative symptoms of psychoses (31–33) and externalizing problems (34).”
BackgroundBlume, J., Dhanasekara, C. S., Kahathuduwa, C. N., & Mastergeorge, A. (2023) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-023-05961-4 · Cited by 14 · see citing works
“…function abilities of those with ASD are also of great interest to the developmental science community, far less empirical work to date has focused on understanding the interplay between executive functioning and social skills (Andersen et al., 2015; Bertollo et al., 2020; Hollocks et al., 2014).”
Ghiotto, C., Silva, C., Charvin, I., Atzori, P., Givaudan, M., Fonséca, D. D., & Bat‐Pitault, F. (2022) · European Eating Disorders Review · doi:10.1002/erv.2904 · Cited by 15 · see citing works
“Concerning ASD our results are in agreement with Hollocks' et al., study (Hollocks et al., 2014), who found a strong association between anxiety and set‐ shifting, as evaluated by a card sorting task and the TMT in adolescents with ASD.”
ResultKimura, Y., Fujioka, T., Jung, M., Fujisawa, T. X., Tomoda, A., & Kosaka, H. (2020) · Psychiatry Research · doi:10.1016/j.psychres.2020.113503 · Cited by 15 · see citing works
Anxiety relates to classroom executive function problems in students with ASD, but not ADHD
Dieckhaus, M. F. S., Hardy, K. K., Anthony, L. G., Verbalis, A. D., Kenworthy, L. E., & Pugliese, C. E. (2021) · Research in Autism · doi:10.1016/j.rasd.2021.101739 · Cited by 14 · see citing works
Uljarević, M., Frazier, T. W., Rached, G., Busch, R. M., Klaas, P., Srivastava, S., Martínez-Agosto, J. A., Şahin, M., Eng, C., & Hardan, A. Y. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-04881-5 · Cited by 14 · see citing works
Georgoula, C., Ferrín, M., Pietraszczyk-Kędziora, B., Amaia Hervas, G., Marret, S., Oliveira, G., Rosier, A., Crutel, V., Besse, E., Severo, C. A., et al. (2022) · Child Psychiatry & Human Development · doi:10.1007/s10578-022-01328-5 · Cited by 14 · see citing works
Uljarević, M., McCabe, K., Angkustsiri, K., Simon, T. J., & Hardan, A. Y. (2019) · Autism Research · doi:10.1002/aur.2194 · Cited by 14 · see citing works
Lupi, E., Tucci, F., Casula, L., Novello, R. L., Guerrera, S., Vicari, S., & Valeri, G. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1092164 · Cited by 16 · see citing works
“, 2014) and emotional and behavioral problems over time (Hollocks et al., 2014; Lawson et al., 2015).”
BackgroundHealth, psychosocial and cognitive factors associated with anxiety symptoms
Mendoza, L. S. M., Trujillo‐Güiza, M. L., Forero, D. A., & Báez, S. (2024) · Current Psychology · doi:10.1007/s12144-024-05998-3 · Cited by 13 · see citing works
“…lower perfor - mance in executive functions to be associated with higher anxiety levels in populations such as primary care patients, older women, and neurodiverse individuals (Hollocks et al., 2014 ; Nyberg et al., 2021 ; Parra-Díaz et al., 2021 ; Predescu et al., 2020 ; Rozzini et al., 2009 ).”
InfluentialBarnes, G. L., Ozsivadjian, A., Baird, G., Absoud, M., & Hollocks, M. J. (2025) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-024-06246-0 · Cited by 12 · see citing works
Self-citationGodoy, P. B. G., Shephard, E., Milosavljevic, B., Johnson, M. H., Charman, T., The BASIS Team, Baron‐Cohen, S., Bedford, R., Bolton, P., Chandler, S., et al. (2020) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-020-04732-9 · Cited by 12 · see citing works
Self-citationWong, O. W. H., Barzilay, R., Lam, A. M. W., Chan, S. S. M., Calkins, M. E., Gur, R. E., & Gur, R. C. (2022) · Psychological Medicine · doi:10.1017/s0033291722001787 · Cited by 13 · see citing works
“Studies have demonstrated that executive dysfunction in ASD could be related to psychopathology such as anxiety (Hollocks et al., 2014), depressive disorders (Wallace et al., 2016), aggressive behaviors (Lawson et al., 2015), and ADHD (Craig et al., 2016).”
BackgroundHollocks, M. J., Wood, J. J., Storch, E. A., Cho, A. C., Kerns, C. M., & Kendall, P. C. (2022) · Journal of Clinical Child & Adolescent Psychology · doi:10.1080/15374416.2022.2025596 · Cited by 12 · see citing works
“Consistent with the previous research showing no significant relationships between measures of social cognition and anxiety in ASD (Hollocks et al., 2014), this study found that social cognition did not predict CBT treatment response.”
BackgroundResultSelf-citationHigh autistic traits linked with reduced performance on affective task switching: An ERP study
Zhou, S., Chen, Z., Liu, G., Ma, L., & Liu, Y. (2024) · NeuroImage · doi:10.1016/j.neuroimage.2024.120855 · Cited by 12 · see citing works
“These psychopathological variables may influence affective task switching performance (Hollocks et al., 2014; McArthur et al., 2022).”
BackgroundBagnall, R., Cadman, A., Russell, A., Brosnan, M., Otte, M., & Maras, K. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1117415 · Cited by 13 · see citing works
“Elevated anxiety is associated with poorer executive functioning in autistic adolescents (Hollocks et al., 2014), and broader socio-cognitive processing difficulties (Velikonja et al.”
BackgroundFossum, I. N., Orm, S., Andersen, P. N., Geurts, H. M., Øie, M. G., & Skogli, E. W. (2023) · Developmental Neuropsychology · doi:10.1080/87565641.2023.2206663 · Cited by 12 · see citing works
“In a cross-sectional study on children and adolescents with ASD, more EF difficulties were associated with more symptoms of anxiety, but not depression (Hollocks et al., 2014).”
BackgroundGenova, H. M., Kallen, M. A., Sherwood, K. L., DaWalt, L. S., Bishop, L., Telfer, D., Brown, C., Sanchez, B., & Smith, M. J. (2023) · Journal of Vocational Rehabilitation · doi:10.3233/jvr-230009 · Cited by 11 · see citing works
Trimarco, B., Manti, F., Nardecchia, F., Melogno, S., Testa, M., Meledandri, G., Carducci, C., Penge, R., & Leuzzi, V. (2020) · Molecular Genetics and Metabolism Reports · doi:10.1016/j.ymgmr.2020.100577 · Cited by 10 · see citing works
“A number of studies have investigated the relationship between EF and emotional symptoms: Cederlund and colleagues [42] found that depressive difficulties and EF impairments often co-occur in adolescents with ASD and Hollocks and colleagues [43] found a relationship between EF and anxiety symptoms.”
BackgroundJertberg, R., Begeer, S., Geurts, H. M., Chakrabarti, B., & der Burg, E. V. (2025) · Autism Research · doi:10.1002/aur.70015 · Cited by 9 · see citing works
Chan, N., Sanner, C. M., McGregor, H. A., Preston, A. E., & Neece, C. L. (2021) · Journal of Mental Health Research in Intellectual Disabilities · doi:10.1080/19315864.2021.1883781 · Cited by 10 · see citing works
“…social communication deficits, higher rates of being bullied) may place those in this group at higher risk for various psychiatric disorders (Hollocks et al., 2014; Rowley et al., 2012), emphasizing the need for more research to better understand and support the mental health of those in…”
BackgroundMunsell, E. G. S., Orsmond, G. I., Fulford, D., & Coster, W. J. (2021) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-021-05306-z · Cited by 9 · see citing works
Pugliese, C. E., Handsman, R., You, X., Anthony, L. G., Vaidya, C. J., & Kenworthy, L. E. (2024) · Autism · doi:10.1177/13623613241246091 · Cited by 8 · see citing works
“Specifically, we expect an EF profile characterized by inflexibility will be uniquely associated with anxiety, depression, and aggression (e.g. Hollocks et al., 2014; Lawson et al., 2015).”
Edmunds, S. R., MacNaughton, G. A., Rueda, M. R., Cómbita, L. M., & Faja, S. (2022) · Autism Research · doi:10.1002/aur.2735 · Cited by 7 · see citing works
“Anxiety features are correlated with reduced EF in autism (Hollocks et al., 2014), and it is thought that anxiety may directly blunt EF skills like attention, shifting, and working memory (Corbetta & Shulman, 2002) and potentially inhibit learning.”
BackgroundHarrop, C., Bodfish, J. W., Lecavalier, L., Dallman, A., Jones, D. R., Pritchett, J., Whitten, A., & Boyd, B. A. (2023) · Journal of Autism and Developmental Disorders · doi:10.1007/s10803-023-06079-3 · Cited by 7 · see citing works
“For example, children with anxiety have been found to perform more poorly on executive functioning tasks (Geronimi et al., 2016; Han et al., 2016; Murphy et al., 2018; Toren et al., 2000) and this relationship has been extended to autism (Hollocks et al., 2014, 2022; Wallace et al., 2016).”
Bao, R., Leahy, A. A., Lubans, D. R., Diallo, T., Beauchamp, M. R., Smith, J. J., Hillman, C. H., & Wade, L. (2024) · Journal of Sports Sciences · doi:10.1080/02640414.2024.2422203 · Cited by 7 · see citing works
“…and social-emotional health (Diamond, 2013; Riggs et al., 2006; Yang et al., 2022), whereas impaired executive functions may have detrimental effects on physical (e.g., a risk of obesity (Mamrot & Hanć, 2019)) and mental (e.g., depression (Gardiner & Iarocci, 2018; Hollocks et al., 2014)) health.”
Su, W. C., Srinivasan, S. M., & Bhat, A. N. (2025) · Disability and Rehabilitation · doi:10.1080/09638288.2025.2465600 · Cited by 7 · see citing works
“These findings align with previous studies linking EF difficulties to both externalizing (e.g., aggression) and internalizing behaviors (e.g., anxiety and depression) in children with ASD [19,43].”
Cognitive-Behavioral Principles and Their Applications Within Autism Spectrum Disorder
Ryan, P. M., Kaskas, M. M., & Davis, T. E. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805122-1.00006-5 · Cited by 6 · see citing works
Profiles of circumscribed interests in autistic youth
Spackman, E. K., Smillie, L. D., Frazier, T. W., Hardan, A. Y., Alvares, G. A., Whitehouse, A., & Uljarević, M. (2023) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2023.1037967 · Cited by 6 · see citing works
“Therefore, future studies may wish to explore other potential third variables, such as executive functioning or self-regulation, both of which have been linked to anxiety and CI (Anthony et al., 2013; Hollocks et al., 2014; Demetriou et al., 2019; Faja and Nelson Darling, 2019).”
BackgroundAnxiety Disorders in Autistic People
Schiltz, H. K., McVey, A. J., & Lord, C. (2024) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2024.04.016 · Cited by 5 · see citing works
- Authors
- Hollocks, M. J., Jones, C. R. G., Pickles, A., Baird, G., Happé, F., Charman, T., & Simonoff, E.
- Affiliations
- King's College London (GB)
- Cardiff University (GB)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- MRC SGDP Research Centre Institute of Psychiatry King's College London London United Kingdom
- Corresponding author
- Hollocks, Matthew J.
- ORCID
- Venue
- Autism Research
- Publisher
- Wiley
- Published
- 2014-03-12
- Volume
- 7
- Issue
- 2
- Pages
- 216-228
- ISSN
- 1939-3792 (ISSN-L)
- 1939-3806
- OpenAlex
- W2100273199
- Cited by
- 150
- References
- 77
- Citations by year
- 2026: 9 · 2025: 12 · 2024: 15 · 2023: 19 · 2022: 12 · 2021: 19 · 2020: 16 · 2019: 7 · 2018: 12 · 2017: 12 · 2016: 4 · 2015: 10 · 2014: 3
- FWCI
- 5.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Autism Research (publishedVersion)
- PubMed (publishedVersion)
- ORCA Online Research @Cardiff (Cardiff University) (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- Funders
- Medical Research Council (G0400065)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- autism spectrum disorder, adolescents, executive function, social cognition, anxiety symptoms, depressive symptoms, anxiety comorbidity, neurocognitive function
- MeSH terms
- Adolescent, Anxiety Disorders, Child Development Disorders, Pervasive, Culture, Depressive Disorder, Emotions, Facial Expression, Female, Humans, Male, Neuropsychological Tests, Surveys and Questionnaires, Statistics as Topic, Comorbidity, Intention, Executive Function, Theory of Mind, Emotional Intelligence
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