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Cited by 33Autism Spectrum Disorder ResearchDown syndrome and intellectual disability researchAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Emotional dysregulation and uncertainty intolerance as transdiagnostic mediators of anxiety in adults with autism spectrum disorders and intellectual disability

Sáez-Suanes, Gema P., García-Villamisar, Domingo, del Pozo Armentia, Araceli, Dattilo, John·2020·Research in Developmental Disabilities
DOI 10.1016/j.ridd.2020.103784
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Abstract

BACKGROUND: There is extensive documentation supporting the comorbidity of anxiety and autistic spectrum disorder (ASD). Transdiagnostic factors such as executive functions, emotion regulation, and uncertainty intolerance are associated with anxiety in ASD. AIM: The primary aim of this paper is to study anxiety symptoms in adults with ASD and ID and their relationship with transdiagnostic variables. METHOD: 121 adults (M = 35.46 years, SD = 9.46) with ASD and intellectual disabilities (ID) were evaluated to determine the predictive and mediating role of executive functioning, emotional regulation and intolerance to uncertainty. RESULTS: Hierarchical linear regression showed uncertainty intolerance was a predictor of anxiety. A multiple mediation analysis supported the mediating role of uncertainty intolerance and emotional regulation between ASD and anxiety. CONCLUSIONS AND IMPLICATIONS: These findings suggest that interventions designed to reduce anxiety symptoms in people with ASD and ID should include among their goals emotional regulation and especially intolerance of uncertainty.

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  • Sáez-Suanes et al. (2020) showed that both intolerance of uncertainty and emotion regulation played independent mediating roles between autism-related behavioural traits and anxiety in autistic adults with intellectual disability.

    “Finally, a recent study of autistic adults with ID by Sáez-Suanes et al. (2020) showed that both IU and ER played independent mediating roles between autism-related behavioural traits and anxiety.”

    From Examining a model of anxiety in autistic adults (2024) · cites this paper as Sáez-Suanes et al. (2020)

  • Intolerance of uncertainty was a predictor of anxiety, and intolerance of uncertainty and emotional regulation mediated the relationship between autism spectrum disorder and anxiety.

    “Results showed that IU was a predictor of anxiety, and supported the mediating role of UI and emotional regulation between ASD and anxiety”

    From Emotional dysregulation as a part of the autism spectrum continuum: a literature review from late childhood to adulthood (2023) · cites this paper as [56]

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Authors
Sáez-Suanes, G. P., García-Villamisar, D., del Pozo Armentia, A., & Dattilo, J.
Affiliations
  • Universidad Complutense de Madrid (ES)
  • Pennsylvania State University (US)
ORCID
Venue
Research in Developmental Disabilities
Publisher
Elsevier BV
Published
2020-11
Volume
106
Pages
103784
ISSN
0891-4222 (ISSN-L)
DOI
10.1016/j.ridd.2020.103784
OpenAlex
W3090676042
Cited by
33
References
79
Citations by year
2026: 5 · 2025: 4 · 2024: 9 · 2023: 8 · 2022: 4 · 2021: 3
FWCI
2.02
Type
journal article
Language
en
Update notices
erratum (2021-06-01)
Open access
closed
Licence
Locations
  • Research in Developmental Disabilities (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Down syndrome and intellectual disability research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Keywords
autism spectrum disorder, intellectual disability, anxiety, intolerance of uncertainty, emotional dysregulation, emotion regulation, executive function, transdiagnostic factors, mediation, comorbidities, adults
MeSH terms
Autism Spectrum Disorder, Adult, Anxiety, Anxiety Disorders, Humans, Intellectual Disability, Uncertainty

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