Cited by 529Schizophrenia research and treatmentFunctional Brain Connectivity StudiesHallucinations in medical conditions

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Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations

Lawrie, Stephen M, Buechel, Christian, Whalley, Heather C, Frith, Christopher D, Friston, Karl J, Johnstone, Eve C·2002·Biological Psychiatry

DOI 10.1016/s0006-3223(02)01316-1

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Abstract

Background We used functional magnetic resonance imaging (fMRI) to investigate the frontotemporal disconnection hypothesis of schizophrenia.Methods Eight DSM-IV schizophrenia patients and 10 control subjects were studied with fMRI while they thought of the missing last word in 128 visually presented sentences. The fMRI data were analyzed comparing the effect of sentence completion (vs. rest) using a random effects analysis.Results There were no significant group differences in regional brain responses. Correlation coefficients between left temporal cortex (x = -54, y = -42, z = 3) and left dorsolateral prefrontal cortex (x = -39, y = 12, z = 24) were significantly lower in the schizophrenic group and were negatively correlated with the severity of auditory hallucinations.Conclusions Previous demonstrations of hypofrontality in schizophrenia may reflect particular task requirements. Frontotemporal functional connectivity is reduced in schizophrenia and may be associated with auditory hallucinations.

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Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Co-planar stereotaxic atlas of the human brain
Laitinen, L. (1989) · Clinical Neurology and Neurosurgery · doi:10.1016/0303-8467(89)90128-5 · Cited by 7,565
The Effects of Clozapine, Risperidone, and Olanzapine on Cognitive Function in Schizophrenia
Meltzer, H. Y., & McGurk, S. R. (1999) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a033376 · Cited by 1,021
The Hayling and Brixton Tests
Burgess, P. W., & Shallice, T. (1997) · UCL Discovery (University College London) · Cited by 1,008
Response suppression, initiation and strategy use following frontal lobe lesions
Burgess, P. W., & Shallice, T. (1996) · Neuropsychologia · doi:10.1016/0028-3932(95)00104-2 · Cited by 854 · cited 1×
“This task is sensitive to lesions of the frontal lobe (Burgess and Shallice 1996) and activates frontal and temporal regions (Nathaniel-James et al 1997).”
Background
A standardized psychiatric assessment scale for rating chronic psychotic patients
Krawiecka, M., Goldberg, D. P., & Vaughan, M. (1977) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1977.tb00174.x · Cited by 680
Regional Brain Activity in Chronic Schizophrenic Patients during the Performance of a Verbal Fluency Task
Frith, C., Friston, K. J., Herold, S., Silbersweig, D., Fletcher, P. C., Cahill, C., Dolan, R. J., Frackowiak, R. S. J., & Liddle, P. F. (1995) · The British Journal of Psychiatry · doi:10.1192/bjp.167.3.343 · Cited by 424
Prefrontal function in schizophrenia: confounds and controversies
Weinberger, D. R., & Berman, K. F. (1996) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1996.0135 · Cited by 414
Completion norms for 329 sentence contexts
Bloom, P. A., & Fischler, I. (1980) · Memory & Cognition · doi:10.3758/bf03213783 · Cited by 289
Functional magnetic resonance imaging of schizophrenic patients and comparison subjects during word production
Yurgelun-Todd, D. A., WATERNAUX, C. M., Cohen, B. M., Gruber, S. A., English, C. D., & Renshaw, P. F. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.2.200 · Cited by 242

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Stephan, K. E., Baldeweg, T., & Friston, K. J. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.10.005 · Cited by 841
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Pettersson-Yeo, W., Allen, P., Benetti, S., McGuire, P., & Mechelli, A. (2011) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2010.11.004 · Cited by 712
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Sigurdsson, T., Stark, K. L., Karayiorgou, M., Gogos, J. A., & Gordon, J. A. (2010) · Nature · doi:10.1038/nature08855 · Cited by 702
Beyond hypofrontality: A quantitative meta‐analysis of functional neuroimaging studies of working memory in schizophrenia
Glahn, D. C., Ragland, J. D., Abramoff, A., Barrett, J., Laird, A. R., Bearden, C. E., & Velligan, D. I. (2005) · Human Brain Mapping · doi:10.1002/hbm.20138 · Cited by 647
The hallucinating brain: a review of structural and functional neuroimaging studies of hallucinations
Allen, P., Larøi, F., McGuire, P. K., & Aleman, A. (2008) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2007.07.012 · Cited by 579
Regionally specific disturbance of dorsolateral prefrontal-hippocampal functional connectivity in schizophrenia
Meyer-Lindenberg, A. S., Olsen, R. K., Kohn, P. D., Brown, T., Egan, M. F., Weinberger, D. R., & Berman, K. F. (2005) · Archives of General Psychiatry · doi:10.1001/archpsyc.62.4.379 · Cited by 574
The dysconnection hypothesis (2016)
Friston, K., Brown, H. R., Siemerkus, J., & Stephan, K. E. (2016) · Schizophrenia Research · doi:10.1016/j.schres.2016.07.014 · Cited by 561
NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development
Krystal, J. H., D'Souza, D. C., Mathalon, D., Perry, E., Belger, A., & Hoffman, R. (2003) · Psychopharmacology · doi:10.1007/s00213-003-1582-z · Cited by 530
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Brunelin, J., Mondino, M., Gassab, L., Haesebaert, F., Gaha, L., Suaud-Chagny, M.-F., Saoud, M., Mechri, A., & Poulet, E. (2012) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.11071091 · Cited by 520
Assessing functional connectivity in the human brain by fMRI
Rogers, B. P., Morgan, V. L., Newton, A. T., & Gore, J. C. (2007) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2007.03.007 · Cited by 511
22q11.2 microdeletions: linking DNA structural variation to brain dysfunction and schizophrenia
Karayiorgou, M., Simon, T. J., & Gogos, J. A. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2841 · Cited by 474
Disruption of cortical association networks in schizophrenia and psychotic bipolar disorder
Baker, J. T., Holmes, A. J., Masters, G. A., Yeo, B. T. T., Krienen, F., Buckner, R. L., & Öngür, D. (2014) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2013.3469 · Cited by 435
Pathways That Make Voices
Hubl, D., Koenig, T. W., Strik, W. K., Federspiel, A., Kreis, R., Boesch, C., Maier, S. E., Schroth, G., Lövblad, K., & Dierks, T. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.7.658 · Cited by 466
Psychobiology of Altered States of Consciousness.
Vaitl, D., Birbaumer, N., Gruzelier, J., Jamieson, G. A., Kotchoubey, B., Kübler, A., Lehmann, D., Miltner, W. H. R., Ott, U., Pütz, P., et al. (2005) · Psychological Bulletin · doi:10.1037/0033-2909.131.1.98 · Cited by 448
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Zhou, Y., Liang, M., Tian, L., Wang, K., Hao, Y., Liu, H., Liu, Z., & Jiang, T. (2007) · Schizophrenia Research · doi:10.1016/j.schres.2007.05.029 · Cited by 444
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Lehmann, D., Faber, P. L., Galderisi, S., Herrmann, W. M., Kinoshita, T., Koukkou, M., Mucci, A., Pascual-Marqui, R. D., Saito, N. H., Wackermann, J., et al. (2005) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2004.05.007 · Cited by 414
Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging
Liang, M., Zhou, Y., Jiang, T., Liu, Z., Tian, L., Liu, H., & Hao, Y. (2006) · Neuroreport · doi:10.1097/01.wnr.0000198434.06518.b8 · Cited by 402
High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain
Avanaki, K., Xia, J., Wan, H., Bauer, A. Q., Culver, J. P., & Wang, L. V. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1311868111 · Cited by 350
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Shen, H., Wang, L., Liu, Y., & Hu, D. (2009) · NeuroImage · doi:10.1016/j.neuroimage.2009.11.011 · Cited by 352
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Shamay‐Tsoory, S., Shur, S., Barcai-Goodman, L., Medlovich, S., Harari, H., & Levkovitz, Y. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2005.10.018 · Cited by 350
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Rotarska-Jagiela, A., van de Ven, V. G., Oertel‐Knöchel, V., Uhlhaas, P. J., Vogeley, K. T., & Linden, D. E. J. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2010.01.001 · Cited by 351
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Waites, A. B., Briellmann, R. S., Saling, M. M., Abbott, D. F., & Jackson, G. D. (2006) · Annals of Neurology · doi:10.1002/ana.20733 · Cited by 328
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Sigurdsson, T., & Duvarci, S. (2016) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2015.00190 · Cited by 309
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Pandya, M. A., Altinay, M. I., Malone, D. A., & Anand, A. (2012) · Current Psychiatry Reports · doi:10.1007/s11920-012-0322-7 · Cited by 327
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Herholz, S. C., Halpern, A. R., & Zatorre, R. J. (2012) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_00216 · Cited by 287
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Sussmann, J. E., Lymer, G. K. S., McKirdy, J. W., Moorhead, T. W. J., Maniega, S. M., Job, D. E., Hall, J., Bastin, M. E., Johnstone, E. C., Lawrie, S. M., et al. (2009) · Bipolar Disorders · doi:10.1111/j.1399-5618.2008.00646.x · Cited by 273
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Vercammen, A., Knegtering, H., den Boer, J. A., Liemburg, E. J., & Aleman, A. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.11.017 · Cited by 261
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Eckert, M. A., Leonard, C. M., Wilke, M., Eckert, M., Richards, T. L., Richards, A. L., & Berninger, V. W. (2005) · Cortex · doi:10.1016/s0010-9452(08)70268-5 · Cited by 161
Oscillations and hippocampal–prefrontal synchrony
Gordon, J. A. (2011) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2011.02.012 · Cited by 167
Diffusion Tensor Magnetic Resonance Imaging of Disruption of Regional White Matter in Schizophrenia
Minami, T., Nobuhara, K., Okugawa, G., Takase, K., Yoshida, T., Sawada, S., Ha-Kawa, S., Ikeda, K., & Kinoshita, T. (2003) · Neuropsychobiology · doi:10.1159/000070583 · Cited by 157
Auditory Oddball Deficits in Schizophrenia: An Independent Component Analysis of the fMRI Multisite Function BIRN Study
Kim, D. I., Mathalon, D. H., Ford, J. M., Mannell, M. V., Turner, J. A., Brown, G. G., Belger, A., Gollub, R. L., Lauriello, J., Wible, C. G., et al. (2008) · Schizophrenia Bulletin · doi:10.1093/schbul/sbn133 · Cited by 159
Cortical Cholinergic Transmission and Cortical Information Processing in Schizophrenia
Sarter, M. (2005) · Schizophrenia Bulletin · doi:10.1093/schbul/sbi006 · Cited by 153
On the role of general system theory for functional neuroimaging
Stephan, K. (2004) · Journal of Anatomy · doi:10.1111/j.0021-8782.2004.00359.x · Cited by 174
Abnormal topological organization of structural brain networks in schizophrenia
Zhang, Y., Lin, L., Lin, C., Zhou, Y., Chou, K., Lo, C. Z., Su, T., & Jiang, T. (2012) · Schizophrenia Research · doi:10.1016/j.schres.2012.08.021 · Cited by 149
Targeting reduced neural oscillations in patients with schizophrenia by transcranial alternating current stimulation
Ahn, S., Mellin, J. M., Alagapan, S., Alexander, M. L., Gilmore, J. H., Jarskog, L. F., & Frӧhlich, F. (2018) · NeuroImage · doi:10.1016/j.neuroimage.2018.10.056 · Cited by 150
Clinical Symptoms and Alpha Band Resting-State Functional Connectivity Imaging in Patients With Schizophrenia: Implications for Novel Approaches to Treatment
Hinkley, L. B. N., Vinogradov, S., Guggisberg, A. G., Fisher, M., Findlay, A. M., & Nagarajan, S. S. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.06.029 · Cited by 149
Neuroimaging of cognitive disability in schizophrenia: Search for a pathophysiological mechanism
Ragland, J. D., Yoon, J. H., Minzenberg, M., & Carter, C. S. (2007) · International Review of Psychiatry · doi:10.1080/09540260701486365 · Cited by 151
Engagement of brain areas implicated in processing inner speech in people with auditory hallucinations
Shergill, S. S., Brammer, M. J., Fukuda, R., Williams, S., Murray, R. M., & McGuire, P. K. (2003) · The British Journal of Psychiatry · doi:10.1192/bjp.182.6.525 · Cited by 152
Functional Disconnection Between the Prefrontal and Parietal Cortices During Working Memory Processing in Schizophrenia: A [15O]H2O PET Study
Kim, J., Kwon, J. S., Park, H., Youn, T., Kang, D. H., Kim, M. S., Lee, D. S., & Lee, M. C. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.5.919 · Cited by 145
fMRI correlates of state and trait effects in subjects at genetically enhanced risk of schizophrenia
Whalley, H. C. (2003) · Brain · doi:10.1093/brain/awh070 · Cited by 145
Dysbindin-1 modulates prefrontal cortical activity and schizophrenia-like behaviors via dopamine/D2 pathways
Papaleo, F., Yang, F., Garcia, S., Chen, J., Lu, B., Crawley, J. N., & Weinberger, D. R. (2010) · Molecular Psychiatry · doi:10.1038/mp.2010.106 · Cited by 148
Subjective Time
(2014) · The MIT Press eBooks · doi:10.7551/mitpress/8516.001.0001 · Cited by 146
Altered resting-state connectivity in subjects at ultra-high risk for psychosis: an fMRI study
Shim, G., Oh, J. S., Jung, W. H., Jang, J. H., Choi, C., Kim, E., Park, H.-Y., Choi, J., Jung, M. H., & Kwon, J. S. (2010) · Behavioral and Brain Functions · doi:10.1186/1744-9081-6-58 · Cited by 143
Dysconnectivity of multiple resting-state networks in patients with schizophrenia who have persistent auditory verbal hallucinations
Wolf, N. D., Sambataro, F., Vasić, N., Frasch, K., Schmid, M., Schönfeldt‐Lecuona, C., Thomann, P. A., & Wolf, R. C. (2011) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.110008 · Cited by 145
Overall brain connectivity maps show cortico‐subcortical abnormalities in schizophrenia
Salvador, R. M., Sarró, S., Gomar, J. J., Ortiz‐Gil, J., Vila‐Rodriguez, F., Capdevila, A., Bullmore, E. T., McKenna, P. J., & Pomarol‐Clotet, E. (2010) · Human Brain Mapping · doi:10.1002/hbm.20993 · Cited by 143
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Drew, L., Crabtree, G. W., Markx, S., Stark, K. L., Chaverneff, F., Xu, B., Mukai, J., Fénelon, K., Hsu, P.-K., Gogos, J. A., et al. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.09.007 · Cited by 142
Functional disconnectivity in subjects at high genetic risk of schizophrenia
Whalley, H. C., Simonotto, E., Marshall, I., Owens, D. G. C., Goddard, N., Johnstone, E. C., & Lawrie, S. M. (2005) · Brain · doi:10.1093/brain/awh556 · Cited by 134
Hallucinations in schizophrenia, sensory impairment, and brain disease: A unifying model
Behrendt, R., & Young, C. (2004) · Behavioral and Brain Sciences · doi:10.1017/s0140525x04000184 · Cited by 137
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Rapoport, J. L., & Gogtay, N. (2010) · International Journal of Developmental Neuroscience · doi:10.1016/j.ijdevneu.2010.10.003 · Cited by 138
Design and analysis of fMRI studies with neurologically impaired patients
Price, C. J., Crinion, J., & Friston, K. J. (2006) · Journal of Magnetic Resonance Imaging · doi:10.1002/jmri.20580 · Cited by 132
Relationships between Gene Expression and Brain Wiring in the Adult Rodent Brain
French, L., & Pavlidis, P. (2011) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1001049 · Cited by 129
Altered Integrity of Perisylvian Language Pathways in Schizophrenia: Relationship to Auditory Hallucinations
Catani, M., Craig, M., Forkel, S. J., Kanaan, R., Picchioni, M., Toulopoulou, T., Shergill, S. S., Williams, S., Murphy, D., & McGuire, P. K. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.06.013 · Cited by 133

Authors: Lawrie, S. M., Buechel, C., Whalley, H. C., Frith, C. D., Friston, K. J., & Johnstone, E. C.
Affiliations: Royal Edinburgh Hospital (GB)
National Hospital for Neurology and Neurosurgery (GB)
ORCID: Lawrie, Stephen M
Whalley, Heather C
Friston, Karl J
Venue: Biological Psychiatry
Publisher: Elsevier BV
Published: 2002-06
Volume: 51
Issue: 12
Pages: 1008-1011
ISSN: 0006-3223 (ISSN-L)
DOI: 10.1016/s0006-3223(02)01316-1
OpenAlex: W2029059267
Cited by: 529
References: 15
Citations by year: 2026: 3 · 2025: 2 · 2024: 9 · 2023: 9 · 2022: 16 · 2021: 20 · 2020: 14 · 2019: 16 · 2018: 24 · 2017: 26 · 2016: 29 · 2015: 24 · 2014: 27 · 2013: 41 · 2012: 33
FWCI: 14.50
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Biological Psychiatry (publishedVersion)
PubMed (publishedVersion)
UCL Discovery (University College London) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Hallucinations in medical conditions
Keywords: schizophrenia, auditory hallucinations, dorsolateral prefrontal cortex, left temporal cortex, hypofrontality, sentence completion task
MeSH terms: Adult, Female, Frontal Lobe, Hallucinations, Humans, Magnetic Resonance Imaging, Male, Neuropsychological Tests, Schizophrenia, Schizophrenic Psychology, Task Performance and Analysis, Temporal Lobe

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Reduced frontotemporal functional connectivity in schizophrenia associated with auditory hallucinations

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