The DOI matches its Crossref record; 56 of the 56 references it cites were found in a registry or an index.
Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies
Abstract
The brown seaweed Adenocystis utricularis (family Adenocystaceae, order Ectocarpales sensu lato) was extracted in parallel with three solvents usually utilized for obtaining fucoidans: distilled water, 2% calcium chloride solution and diluted hydrochloric acid (pH 2) solution. In each case, the extraction was effected at room temperature and then at 70 degrees C. The extraction yields and characteristics of the products were similar in the three cases, with only minor differences. The analytical features of the products indicate that two different types of fucoidans are present in this seaweed. One of them, mostly extracted at room temperature, is composed mainly of L-fucose, D-galactose and ester sulfate (the 'galactofucan'). The other product (the 'uronofucoidan') is the major component of the extracts obtained at 70 degrees C. It is composed mainly of fucose, accompanied by other monosaccharides (mostly Man, but also Glc, Xyl, Rha and Gal), significant amounts of uronic acids and low proportions of sulfate ester. Fractionation with the cationic detergent cetrimide has allowed achieving a better separation of the galactofucan and uronofucoidan components. The galactofucans show a high inhibitory activity against herpes simplex virus 1 and 2, with no cytotoxicity, whereas the uronofucoidans carry no antiviral activity. Structural studies on the galactofucan fractions were carried out by methylation analysis, desulfation and NMR spectroscopy. The fucan constituent is mainly composed of 3-linked alpha-L-fucopyranosyl backbone, mostly sulfated at C-4, and branched at C-2 with non-sulfated fucofuranosyl and fucopyranosyl units, and 2-sulfated fucopyranosyl units. The galactan moiety is more heterogeneous, with predominant D-galactopyranose units linked on C-3 and C-6, and sulfation mostly on C-4, even in terminal non-reducing units. It may be inferred that at least some of these galactose units carry the alpha-configuration.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“A longer extraction time decreases the fucose and sulfate contents, resulting in low-quality fucoidan [23,37].”
From A Review on Fucoidan Structure, Extraction Techniques, and Its Role as an Immunomodulatory Agent (2022) · cites this paper as [37]
In the citing paper
“the galactan moiety, which was also present, was predominantly found to be a backbone structure of (1→3) and (1→6) d-galactopyranose units with sulfation mostly on C-4 [15].”
In the citing paper
“Other algal fucoidans whose structures contain the same α(1→3)-backbone of fucose residues have been found in Analipus japonicas (Ectocarpales), Adenocystis utricularis (Ectocarpales) and Cladosiphon okamuranus (Chordariales) [14,15,39], but the FCSPs from these brown algae also appear to contain other monosaccharides than fucose (Table 2).”
In the citing paper
“Methylation analysis, desulfation and NMR spectroscopy of the FCSPs fractions from Adenocystis utricularis (Ectocarpales) showed that these FCSPs contained the same α-(1→3)-fucopyranose backbone as that found in Chorda filum and Laminaria saccharina FCSPs, and that the fucopyranosyl units were mostly sulfated at C-4, and branched at C-2 with non-sulfated fucopyranosyl units;”
In the citing paper
“Ponce et al. (2003) 17 thus reported that longer extraction time led to poorer fucose content, whereas glucuronic acid increased while sulfate decreased with time, i.e., the sulfate content was highest when glucuronic acid was lowest.17”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [17]
In the citing paper
“It has also been shown by others that longer extraction time at higher temperatures led to higher polysaccharide yield with lower amounts of sulfate and a higher proportion of glucuronic acid.11,17”
From Fucoidans from brown seaweeds: an update on structures, extraction techniques and use of enzymes as tools for structural elucidation (2013) · cites this paper as [17]
Citations
Cites
PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT
Lowry, O. H., Rosebrough, N., Farr, A. L., & Randall, R. (1951) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)52451-6 · Cited by 316,394
Colorimetric Method for Determination of Sugars and Related Substances
DuBois, M., Gilles, K. A., Hamilton, J. K., Rebers, P. A., & Smith, F. (1956) · Analytical Chemistry · doi:10.1021/ac60111a017 · Cited by 52,269
Rapid colorimetric assay for cell growth and survival
Denizot, F., & Lang, R. (1986) · Journal of Immunological Methods · doi:10.1016/0022-1759(86)90368-6 · Cited by 4,935
A simple and rapid method for the permethylation of carbohydrates
Ciucanu, I., & Kerek, F. (1984) · Carbohydrate Research · doi:10.1016/0008-6215(84)85242-8 · Cited by 3,581
A note on the determination of the ester sulphate content of sulphated polysaccharides
Dodgson, K. S., & Price, R. (1962) · Biochemical Journal · doi:10.1042/bj0840106 · Cited by 1,645
A SUBMICRODETERMINATION OF GLUCOSE
Park, J. T., & Johnson, M. J. (1949) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)56635-7 · Cited by 1,574
Measurement of uronic acids without interference from neutral sugars
Filisetti-Cozzi, T. M. C. C., & Carpita, N. C. (1991) · Analytical Biochemistry · doi:10.1016/0003-2697(91)90372-z · Cited by 1,446
Taylor, R., & Conrad, H. E. (1972) · Biochemistry · doi:10.1021/bi00758a009 · Cited by 889
Chemistry and enzymology of marine algal polysaccharides
Percival, E. E., & McDowell, R. H. (1967) · Cited by 686
Baba, M., Snoeck, R., Pauwels, R., & Clercq, E. D. (1988) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.32.11.1742 · Cited by 545
Research works printed but not linked: 3
- Blondin, 1994, Mol. Inmunol., 31, 245
- Stortz, 2000, Curr. Top. Phytochem., 4, 121
- Usov, 1998, Russ. J. Bioorg. Chem., 24, 437
Cited by
Sorted by citations
Fucoidan: Structure and bioactivity
Li, B., Lu, F., Wei, X., & Zhao, R. (2008) · Molecules · doi:10.3390/molecules13081671 · Cited by 1,383
Chemical structures and bioactivities of sulfated polysaccharides from marine algae
Jiao, G., Yu, G., Zhang, J., & Ewart, H. S. (2011) · Marine Drugs · doi:10.3390/md9020196 · Cited by 1,054
Wijesekara, I., Pangestuti, R., & Kim, S.-K. (2011) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2010.10.062 · Cited by 992
Medicinal and pharmaceutical uses of seaweed natural products: A review
Smit, A. J. (2004) · Journal of Applied Phycology · doi:10.1023/b:japh.0000047783.36600.ef · Cited by 806
Ale, M. T., Mikkelsen, J. D., & Meyer, A. S. (2011) · Marine Drugs · doi:10.3390/md9102106 · Cited by 779
Berteau, O. (2003) · Glycobiology · doi:10.1093/glycob/cwg058 · Cited by 769
Antioxidant activity of sulfated polysaccharide fractions extracted from Laminaria japonica
Wang, J., Zhang, Q., Zhang, Z., & Li, Z. (2007) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2007.10.003 · Cited by 745
Marine Polysaccharides from Algae with Potential Biomedical Applications
Raposo, M. F. D. J., Morais, A. M. M. B., & Morais, R. M. S. C. (2015) · Marine Drugs · doi:10.3390/md13052967 · Cited by 712
Liu, J., Willför, S. M., & Xu, C. (2014) · Bioactive Carbohydrates and Dietary Fibre · doi:10.1016/j.bcdf.2014.12.001 · Cited by 641
Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications
Cunha, L., & Grenha, A. (2016) · Marine Drugs · doi:10.3390/md14030042 · Cited by 620
Bioactive potential and possible health effects of edible brown seaweeds
Gupta, S., & Abu-Ghannam, N. (2011) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2011.03.011 · Cited by 608
Characterization of polysaccharides extracted from brown seaweeds
Rioux, L.-E., Turgeon, S. L., & Beaulieu, M. (2007) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2007.01.009 · Cited by 604
Wang, Y., Xing, M., Cao, Q., Ji, A., Liang, H., & Song, S. (2019) · Marine Drugs · doi:10.3390/md17030183 · Cited by 530
Screening for bioactive compounds from algae
Plaza, M., Santoyo, S., Jaime, L., Reina, G. G.-B., Herrero, M., Señoráns, F. J., & Ibáñez, E. (2009) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2009.03.016 · Cited by 504
Michel, G., Tonon, T., Scornet, D., Cock, J. M., & Kloareg, B. (2010) · New Phytologist · doi:10.1111/j.1469-8137.2010.03374.x · Cited by 441
Polysaccharide biological response modifiers
Leung, M. Y. K., Liu, C., Koon, J. C. M., & Fung, K. (2006) · Immunology Letters · doi:10.1016/j.imlet.2006.01.009 · Cited by 410
Rahaman, M. M., Hossain, R., Herrera‐Bravo, J., Islam, M. T., Atolanı, O., Adeyemı, O. S., Owolodun, O. A., Kambizi, L., Daştan, S. D., Călina, D. C., et al. (2023) · Food Science & Nutrition · doi:10.1002/fsn3.3217 · Cited by 402
Therapeutic Effects of Fucoidan: A Review on Recent Studies
Luthuli, S., Wu, S., Cheng, Y., Zheng, X., Wu, M., & Tong, H. (2019) · Marine Drugs · doi:10.3390/md17090487 · Cited by 395
Ghosh, T., Chattopadhyay, K., Marschall, M., Karmakar, P., Mandal, P., & Ray, B. (2008) · Glycobiology · doi:10.1093/glycob/cwn092 · Cited by 393
The Antiviral Activities and Mechanisms of Marine Polysaccharides: An Overview
Wang, W., Wang, S., & Guan, H. (2012) · Marine Drugs · doi:10.3390/md10122795 · Cited by 386
Ale, M. T., & Meyer, A. S. (2013) · RSC Adv. · doi:10.1039/c3ra23373a · Cited by 381
Yuan, Y., & Macquarrie, D. (2015) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2015.04.057 · Cited by 371
Immunomodulatory and Anti-Inflammatory Effects of Fucoidan: A Review
Apostolova, E., Lukova, P., Baldzhieva, A., Katsarov, P., Nikolova, M., Iliev, I. N., Peychev, L. P., Trică, B., Oancea, F., Delattre, C., et al. (2020) · Polymers · doi:10.3390/polym12102338 · Cited by 350
Fucoidan Structure and Activity in Relation to Anti-Cancer Mechanisms
van Weelden, G. H., Bobiński, M. S., Okła, K., van Weelden, W. J., Romano, A., & Pijnenborg, J. M. A. (2019) · Marine Drugs · doi:10.3390/md17010032 · Cited by 340
Deniaud-Bouët, E., Hardouin, K., Potin, P., Kloareg, B., & Hervé, C. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.07.082 · Cited by 320
Deniaud-Bouët, E., Kervarec, N., Michel, G., Tonon, T., Kloareg, B., & Hervé, C. (2014) · Annals of Botany · doi:10.1093/aob/mcu096 · Cited by 317
Antiviral Potential of Algae Polysaccharides Isolated from Marine Sources: A Review
Ahmadi, A., Moghadamtousi, S. Z., AbuBakar, S., & Zandi, K. (2015) · BioMed Research International · doi:10.1155/2015/825203 · Cited by 309
Palanisamy, S., Vinosha, M., Marudhupandi, T., Rajasekar, P., & Prabhu, N. M. (2017) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.03.182 · Cited by 280
Antiviral surfaces and coatings and their mechanisms of action
Rakowska, P. D., Tiddia, M., Faruqui, N., Bankier, C., Pei, Y., Pollard, A. J., Zhang, J., & Gilmore, I. S. (2021) · Communications Materials · doi:10.1038/s43246-021-00153-y · Cited by 275
The seasonal variation of fucoidan within three species of brown macroalgae
Fletcher, H. R., Biller, P., Ross, A. B., & Adams, J. M. M. (2016) · Algal Research · doi:10.1016/j.algal.2016.10.015 · Cited by 270
A highly regular fraction of a fucoidan from the brown seaweed Fucus distichus L.
Bilan, M. I., Grachev, A. A., Ustuzhanina, N. E., Shashkov, A. S., Nifantiev, N. E., & Usov, A. I. (2004) · Carbohydrate Research · doi:10.1016/j.carres.2003.10.028 · Cited by 259
Bioactive Polysaccharides from Seaweeds
Hentati, F., Tounsi, L., Djomdi, D., Pierre, G., Delattre, C., Ursu, A. V., Fendri, I., Abdelkafi, S., & Michaud, P. (2020) · Molecules · doi:10.3390/molecules25143152 · Cited by 254
Yang, C., Chung, D., Shin, I.-S., Lee, H., Kim, J., Lee, Y., & You, S. (2008) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2008.08.006 · Cited by 254
Mak, W., Hamid, N., Liu, T., Lu, J., & White, W. L. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.02.047 · Cited by 253
The Evolution Road of Seaweed Aquaculture: Cultivation Technologies and the Industry 4.0
García‐Poza, S., Leandro, A., Cotas, C., Cotas, J., Marques, J. C., Pereira, L., & Gonçalves, A. M. M. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17186528 · Cited by 265
Fucoidans as a natural bioactive ingredient for functional foods
Vo, T., & Kim, S. (2012) · Journal of Functional Foods · doi:10.1016/j.jff.2012.08.007 · Cited by 237
Stiger‐Pouvreau, V., Bourgougnon, N., & Deslandes, É. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802772-1.00008-7 · Cited by 226
Koh, H. S. A., Lu, J., & Zhou, W. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.02.040 · Cited by 221
Seaweed polysaccharides and their potential biomedical applications
Venkatesan, J., Lowe, B., Anil, S., Manivasagan, P., Kheraif, A. A. A., Kang, K., & Kim, S. (2015) · Starch - Stärke · doi:10.1002/star.201400127 · Cited by 216
Bilan, M. I., Grachev, A. A., Shashkov, A. S., Kelly, M. S., Sanderson, C. J., Nifantiev, N. E., & Usov, A. I. (2010) · Carbohydrate Research · doi:10.1016/j.carres.2010.07.009 · Cited by 215
Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum
Adhikari, U., Mateu, C. G., Chattopadhyay, K., Pujol, C. A., Damonte, E. B., & Ray, B. (2006) · Phytochemistry · doi:10.1016/j.phytochem.2006.05.024 · Cited by 213
Self-citationAlgal fucoidan: structural and size-dependent bioactivities and their perspectives
Morya, V. K., Kim, J.-E., & Kim, E.-K. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-011-3666-8 · Cited by 208
Hu, T., Liú, D., Chen, Y., Wu, J., & Wang, S. (2009) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2009.12.004 · Cited by 205
Mandal, P., Mateu, C. G., Chattopadhyay, K., Pujol, C. A., Damonte, E. B., & Ray, B. (2007) · Antiviral chemistry & chemotherapy · doi:10.1177/095632020701800305 · Cited by 205
Self-citationYuan, Y., Xu, X., Jing, C., Zou, P., Zhang, C., & Li, Y. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.11.061 · Cited by 197
Bioactive compounds in seaweeds: An overview of their biological properties and safety
Rengasamy, K. R. R., Mahomoodally, M. F., Aumeeruddy, M. Z., Zengin, G., Xiao, J., & Kim, D. H. (2019) · Food and Chemical Toxicology · doi:10.1016/j.fct.2019.111013 · Cited by 199
Herpes Simplex Virus Cell Entry Mechanisms: An Update
Madavaraju, K., Koganti, R., Volety, I., Yadavalli, T., & Shukla, D. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.617578 · Cited by 194
Mensah, E. O., Kanwugu, O. N., Panda, P. K., & Adadi, P. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2023.108784 · Cited by 194
Anticancer and Cancer Preventive Properties of Marine Polysaccharides: Some Results and Prospects
Fedorov, S., Ermakova, S., Zvyagintseva, T., & Stonik, V. (2013) · Marine Drugs · doi:10.3390/md11124876 · Cited by 189
Alboofetileh, M., Rezaei, M., Tabarsa, M., Rittà, M., Donalisio, M., Mariatti, F., You, S., Lembo, D., & Cravotto, G. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2018.11.201 · Cited by 185
Hans, N., Malik, A., & Naik, S. N. (2020) · Bioresource Technology Reports · doi:10.1016/j.biteb.2020.100623 · Cited by 184
Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus
Harden, E. A., Falshaw, R., Carnachan, S., Kern, E. R., & Prichard, M. N. (2009) · Antiviral Research · doi:10.1016/j.antiviral.2009.06.007 · Cited by 183
Immanuel, G., Madasamy, S., Marudhupandi, T., Radhakrishnan, S., & Palavesam, A. (2012) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2012.01.003 · Cited by 181
Holtkamp, A. D., Kelly, S., Ulber, R., & Lang, S. (2009) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1790-x · Cited by 175
Hemmingson, J. A., Falshaw, R., Furneaux, R. H., & Thompson, K. (2006) · Journal of Applied Phycology · doi:10.1007/s10811-006-9096-9 · Cited by 171
Antibacterial activities of some marine algae from the Aegean Sea (Turkey)
Taşkın, E., Ozturk, M., Taşkın, E., & Kurt, O. (2007) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2007.000-2439 · Cited by 167
Chanda, M. J., Merghoub, N., & Arroussi, H. E. (2019) · World Journal of Microbiology and Biotechnology · doi:10.1007/s11274-019-2745-3 · Cited by 166
Rioux, L., & Turgeon, S. L. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-418697-2.00007-6 · Cited by 162
Li, B., Wei, X.-J., Sun, J.-L., & Xu, S.-Y. (2006) · Carbohydrate Research · doi:10.1016/j.carres.2006.03.035 · Cited by 161
Wang, J., Zhang, Q., Zhang, Z., Zhang, H., & Niu, X. (2010) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2010.05.010 · Cited by 159
Immunomodulating Activity of Arabinogalactan and Fucoidan In Vitro
Choi, E., Kim, A.-J., Kim, Y.-O., & Hwang, J. (2005) · Journal of Medicinal Food · doi:10.1089/jmf.2005.8.446 · Cited by 158
Ammar, H. H., Lajili, S., Said, R. B., Cerf, D. L., Bouraoui, A., & Majdoub, H. (2015) · DARU Journal of Pharmaceutical Sciences · doi:10.1186/s40199-015-0089-6 · Cited by 158
Kostas, E. T., Adams, J. M. M., Ruíz, H. A., Durán-Jiménez, G., & Lye, G. J. (2021) · Renewable and Sustainable Energy Reviews · doi:10.1016/j.rser.2021.111553 · Cited by 165
Silva, T. M. A., Alves, L. G., Queiroz, K. C. S., Santos, M. G. L., Marques, C. T., Chavante, S. F., Rocha, H. A. O., & Leite, E. L. (2005) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2005000400005 · Cited by 157
Teruya, T., Konishi, T., Uechi, S., Tamaki, H., & Tako, M. (2007) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2007.02.010 · Cited by 156
Rocha, H. A. O., Moraes, F. A., Trindade, E. D. S., Franco, C. R. C., Torquato, R. J. S., Veiga, S. S., Valente, A. P., Mourão, P. A. S., Leite, E. L., Nader, H. B., et al. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501124200 · Cited by 156
Antioxidant and antiproliferative activities of heterofucans from the seaweed Sargassum filipendula
Costa, L. S., Fidelis, G. P., Telles, C. B. S., Dantas-Santos, N., Camara, R. B. G., Cordeiro, S. L., Costa, M. S. S. P., Almeida-Lima, J., Melo-Silveira, R. F., Oliveira, R. M., et al. (2011) · Marine Drugs · doi:10.3390/md9060952 · Cited by 155
Fauziee, N. A. M., Chang, L. S., Mustapha, W. A. W., Nor, A. M., & Lim, S. J. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.11.067 · Cited by 161
Skriptsova, A. V., Shevchenko, N. M., Николаевна, З. Т., & Imbs, T. I. (2009) · Journal of Applied Phycology · doi:10.1007/s10811-009-9438-5 · Cited by 152
Seaweed as a Source of Natural Antioxidants: Therapeutic Activity and Food Applications
Kumar, Y., Tarafdar, A., & Badgujar, P. C. (2021) · Journal of Food Quality · doi:10.1155/2021/5753391 · Cited by 152
Croci, D. O., Cumashi, A., Ushakova, N. A., Preobrazhenskaya, M. E., Piccoli, A. L., Jr., Totani, L., Ustyuzhanina, N. E., Bilan, M. I., Usov, A. I., Grachev, A. A., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0017283 · Cited by 151
Nguyen, T. T., Mikkelsen, M. D., Tran, V. H. N., Trang, V. T. D., Rhein‐Knudsen, N., Holck, J., Rasin, A. B., Cao, H. T. T., Van, T. T. T., & Meyer, A. S. (2020) · Marine Drugs · doi:10.3390/md18060296 · Cited by 150
A Review on Fucoidan Structure, Extraction Techniques, and Its Role as an Immunomodulatory Agent
Jayawardena, T. U., Nagahawatta, D. P., Fernando, I. P. S., Kim, Y.-T., Kim, J.-S., Kim, W.-S., Lee, J. S., & Jeon, Y.-J. (2022) · Marine Drugs · doi:10.3390/md20120755 · Cited by 149
Peasura, N., Laohakunjit, N., Kerdchoechuen, O., & Wanlapa, S. (2015) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2015.09.030 · Cited by 149
A Comprehensive and Comparative Analysis of the Fucoidan Compositional Data Across the Phaeophyceae
Ponce, N. M. A., & Stortz, C. A. (2020) · Frontiers in Plant Science · doi:10.3389/fpls.2020.556312 · Cited by 150
Self-citationWang, W., Wu, J., Zhang, X., Hao, C., Zhao, X., Jiao, G., Shan, X., Tai, W., & Yu, G. (2017) · Scientific Reports · doi:10.1038/srep40760 · Cited by 147
Huang, C.-Y., Wu, S.-J., Yang, W.-N., Kuan, A.-W., & Chen, C.-Y. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2015.11.100 · Cited by 143
Lowe, B., Venkatesan, J., Anil, S., Shim, M. S., & Kim, S. (2016) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2016.02.054 · Cited by 143
Foley, S. A., Szegezdi, E., Mulloy, B., Samali, A., & Tuohy, M. G. (2011) · Journal of Natural Products · doi:10.1021/np200124m · Cited by 142
Cell Wall Polysaccharides of Marine Algae
Synytsya, A., Čopı́ková, J., Kim, W. J., & Park, Y. I. (2015) · Springer eBooks · doi:10.1007/978-3-642-53971-8_22 · Cited by 144
Pradhan, B., Patra, S., Nayak, R., Behera, C., Dash, S. R., Nayak, S., Sahu, B. B., Bhutia, S. K., & Jena, M. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.09.019 · Cited by 143
Bioactive Compounds and Properties of Seaweeds—A Review
Pal, A., Kamthania, M., & Kumar, A. (2014) · OALib · doi:10.4236/oalib.1100752 · Cited by 141
Fucoidans — sulfated polysaccharides of brown algae
Usov, A. I., & Bilan, M. I. (2009) · Russian Chemical Reviews · doi:10.1070/rc2009v078n08abeh004063 · Cited by 141
Praveen, M. A., Parvathy, K. R. K., Balasubramanian, P., & Jayabalan, R. (2019) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2019.08.011 · Cited by 140
Zou, P., Lu, X., Zhao, H., Yuan, Y., Meng, L., Zhang, C., & Li, Y. (2019) · Frontiers in Plant Science · doi:10.3389/fpls.2019.00048 · Cited by 135
Palanisamy, S., Vinosha, M., Marudhupandi, T., Rajasekar, P., & Prabhu, N. M. (2017) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2017.04.085 · Cited by 133
Rajauria, G., Ravindran, R., García‐Vaquero, M., Rai, D. K., Sweeney, T., & O’Doherty, J. V. (2020) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2020.106332 · Cited by 132
Matos, G. S., Pereira, S. G., Genisheva, Z. A., Gomes, A., Teixeira, J. A., & Rocha, C. M. R. (2021) · Foods · doi:10.3390/foods10030516 · Cited by 132
Liu, J., Wu, S., Chen, L., Li, Q., Shen, Y.-Z., Li, J., Zhang, X., Chen, P., Wu, M., Choi, J., et al. (2019) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2019.11.113 · Cited by 132
Kim, K., Lee, O., & Lee, B.-Y. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.03.010 · Cited by 129
Saeed, M., Arain, M. A., Fazlani, S. A., Marghazani, I. B., Umar, M., Soomro, J., Bhutto, Z. A., Soomro, F., Noreldin, A. E., El-Hack, M. E. A., et al. (2021) · Aquaculture Nutrition · doi:10.1111/anu.13233 · Cited by 126
Hypolipidemic effect of fucoidan from Laminaria japonica in hyperlipidemic rats
Huang, L., Wen, K., Gao, X., & Liu, Y. (2010) · Pharmaceutical Biology · doi:10.3109/13880200903150435 · Cited by 125
Cassolato, J. E. F., Noseda, M. D., Pujol, C. A., Pellizzari, F., Damonte, E. B., & Duarte, M. E. R. (2008) · Carbohydrate Research · doi:10.1016/j.carres.2008.09.014 · Cited by 124
Self-citationYang, Q., Yang, R., Li, M., Zhou, Q., Liang, X.-P., & Elmada, Z. C. (2014) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2014.09.003 · Cited by 123
Chollet, L., Saboural, P., Chauvierre, C., Villemin, J.-N., Letourneur, D., & Chaubet, F. (2016) · Marine Drugs · doi:10.3390/md14080145 · Cited by 127
Anisha, G. S., Padmakumari, S., Patel, A. K., Pandey, A., & Singhania, R. R. (2022) · Bioengineering · doi:10.3390/bioengineering9090472 · Cited by 121
Abdel‐Latif, H. M. R., Dawood, M. A. O., Alagawany, M. M., Faggio, C., Nowosad, J., & Kucharczyk, D. (2022) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2022.01.039 · Cited by 118
Rabanal, M., Ponce, N. M. A., Navarro, D. A., Gomez, R. M., & Stortz, C. A. (2013) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2013.10.019 · Cited by 120
Self-citationHeterofucans from Dictyota menstrualis have anticoagulant activity
Albuquerque, I. R. L., Queiroz, K. C. S., Alves, L. G., dos Santos, E. A., Leite, E. L., & Rocha, H. A. O. (2004) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2004000200002 · Cited by 116
Sun, Q., Li, Y., Ni, L., Li, Y., Cui, Y., Jiang, S.-L., Xie, E., Du, J., Dèng, F., & Dong, C.-X. (2019) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2019.115487 · Cited by 114
Metadata
- Authors
- Ponce, N. M. A., Pujol, C. A., Damonte, E. B., Flores, M. L., & Stortz, C. A.
- Affiliations
- Universidad de Buenos Aires (AR)
- Corresponding author
- Stortz, Carlos A.
- Venue
- Carbohydrate Research
- Publisher
- Elsevier BV
- Published
- 2003-01
- Volume
- 338
- Issue
- 2
- Pages
- 153-165
- ISSN
- 0008-6215 (ISSN-L)
- OpenAlex
- W1981755056
- Cited by
- 484
- References
- 56
- Citations by year
- 2026: 5 · 2025: 21 · 2024: 20 · 2023: 14 · 2022: 40 · 2021: 40 · 2020: 32 · 2019: 23 · 2018: 24 · 2017: 25 · 2016: 18 · 2015: 24 · 2014: 22 · 2013: 23 · 2012: 21
- FWCI
- 11.76
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Carbohydrate Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Aquatic Science › Seaweed-derived Bioactive Compounds
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Polysaccharides and Plant Cell Walls
- Keywords
- fucoidan, brown algae, antiviral activity, herpes simplex virus type 1, herpes simplex virus type 2, sulfate esters, uronic acid, extraction methods, sulfated polysaccharides
- MeSH terms
- Animals, Antiviral Agents, Cell Survival, Chlorocebus aethiops, Chemical Fractionation, Polysaccharides, Seaweed, Vero Cells, Molecular Structure, Herpesvirus 2, Human, Herpesvirus 1, Human, Inhibitory Concentration 50
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
