The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Risk factors for age-related macular degeneration
Abstract
Objective To assess the prevalence and potential risk factors for late age-related macular degeneration (AMD) in three racially similar populations from North America, Europe, and AUSTRALIA:Design Combined analysis of population-based eye disease prevalence data.Participants There were 14,752 participants with gradable photographs from the Beaver Dam Eye Study (n = 4756), Rotterdam Study (n = 6411), and Blue Mountains Eye Study (n = 3585).Main outcome measures AMD diagnosis was made from masked grading of stereo macular photographs. Final classification of AMD cases was agreed by consensus between study investigators.Results AMD prevalence was strongly age related. Overall, AMD was present in 0.2% of the combined population aged 55 to 64 years, rising to 13% of the population older than 85 years. Prevalence of neovascular AMD (NV) increased from 0.17% among subjects aged 55 to 64 years to 5.8% for those older than 85 years. Prevalence of pure geographic atrophy (GA) increased from 0.04% to 4.2% for these age groups. There were no significant gender differences in the prevalence of NV or GA. Subjects in the Rotterdam population had a significantly lower age-adjusted and smoking-adjusted risk of NV than subjects in the Beaver Dam and Blue Mountains populations. Apart from age, tobacco smoking was the only risk factor consistently associated with any form of AMD in all sites separately and in pooled analyses over the three sites.Conclusions These combined data from racially similar communities across three continents provide strong and consistent evidence that tobacco smoking is the principal known preventable exposure associated with any form of AMD.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“In total, data from 18 prospective, cross-sectional studies and 8 case control studies [12,24-26,28,30,31,33-47,49-54,57-73] were included in the final analysis, contributing a sample of some 94,058 patients (ranging from 261 to 22,071) including 3,178 (ranging from 8 to 776) late AMD cases.”
From Clinical risk factors for age-related macular degeneration: a systematic review and meta-analysis (2010) · cites this paper as [25]
In the citing paper
“Age is the strongest risk factor associated with the development of AMD (3, 112, 140) (Figure 3).”
From Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration (2009) · cites this paper as [140]
In the citing paper
“The pooled data from two population-based studies reveal an estimated prevalence of advanced AMD of ~0.2% in ages 55 to 64, increasing to 13% in those older than 85 years (140).”
From Unraveling a Multifactorial Late-Onset Disease: From Genetic Susceptibility to Disease Mechanisms for Age-Related Macular Degeneration (2009) · cites this paper as [140]
In the citing paper
“Female sex may be a risk factor in individuals aged over 75 years,16 with the relative risk for neovascular age-related macular degeneration in women possibly as much as twice that observed in age-matched men.”
From Age-related macular degeneration (2008) · cites this paper as [16]
In the citing paper
“These three large population-based studies have found that the incidence of advanced age-related macular degeneration increases with age, as does the development of large drusen and pigmentary changes.”
From Age-related macular degeneration (2008) · cites this paper as [16]
In the citing paper
“Data pooled from three population-based studies—the Beaver Dam Eye Study, the Rotterdam Study, and the Blue Mountains Eye Study—have estimated the prevalence of advanced age-related macular degeneration to be 0·2% in those aged 55–64 years, increasing to 13% in those older than 85 years.16”
From Age-related macular degeneration (2008) · cites this paper as [16]
Citations
Cites
Bird, A. C., Bressler, N. M., Bressler, S. B., Chisholm, I. H., Coscas, G., Davis, M. D., de Jong, P. T. V. M., Klaver, C. C. W., Klein, B. E. K., Klein, R., et al. (1995) · Survey of Ophthalmology · doi:10.1016/s0039-6257(05)80092-x · Cited by 1,926
Self-citationPrevalence of age-related maculopathy
Klein, R., Klein, B. E. K., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)31871-8 · Cited by 1,845
Self-citationKlein, R., Klein, R., Moss, S. E., & Linton, K. L. P. (1992) · Ophthalmology · doi:10.1016/s0161-6420(92)32011-1 · Cited by 1,382
Self-citationLeibowitz, H. M., Krueger, D. E., Maunder, L. R., Milton, R. C., KINI, M. M., Kahn, H. A., Nickerson, R. J., Pool, J., Colton, T., Ganley, J. P., et al. (1980) · PubMed · Cited by 1,250
The Wisconsin Age-related Maculopathy Grading System
Klein, R., Davis, M. D., Magli, Y. L., Segał, P., Klein, R., & Hubbard, L. D. (1991) · Ophthalmology · doi:10.1016/s0161-6420(91)32186-9 · Cited by 1,188
Self-citationThe Five-year Incidence and Progression of Age-related Maculopathy
Klein, R., Klein, R., Jensen, S. C., & Meuer, S. M. (1997) · Ophthalmology · doi:10.1016/s0161-6420(97)30368-6 · Cited by 1,154
Self-citationPrevalence of age-related maculopathy in Australia
Mitchell, P., Smith, W., Attebo, K., & Wang, J. J. (1995) · Ophthalmology · doi:10.1016/s0161-6420(95)30846-9 · Cited by 1,062
Self-citationThe Prevalence of Age-related Maculopathy in the Rotterdam Study
Vingerling, J. R., Dielemans, I., Hofman, A., Grobbee, D. E., Hijmering, M., Kramer, C. F. L., & de Jong, P. T. V. M. (1995) · Ophthalmology · doi:10.1016/s0161-6420(95)31034-2 · Cited by 815
Drusen and Disciform Macular Detachment and Degeneration
Gass, J. D. M. (1973) · Archives of Ophthalmology · doi:10.1001/archopht.1973.01000050208006 · Cited by 593
Senile macular degeneration: a case-control study
HYMAN, L. G., LILIENFELD, A. M., FERRIS, F. L., & FINE, S. L. (1983) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113629 · Cited by 587
Cited by
Sorted by citations
Items 201–300 of 1,000
The influence of sublethal blue light exposure on human RPE cells.
(2009) · PubMed Central · Cited by 88
The Human Eye Proteome Project: Perspectives on an emerging proteome
Semba, R. D., Enghild, J. J., Venkatraman, V., Dyrlund, T. F., & Eyk, J. E. V. (2013) · PROTEOMICS · doi:10.1002/pmic.201300075 · Cited by 90
The Association between the Lipids Levels in Blood and Risk of Age-Related Macular Degeneration
Wang, Y., Wang, M., Zhang, X., Zhang, Q., Nie, J., Zhang, M., Liu, X., & Ma, L. (2016) · Nutrients · doi:10.3390/nu8100663 · Cited by 88
Wegscheider, B. J., Weger, M., Renner, W., Steinbrugger, I., März, W., Mossböck, G., Temmel, W., El‐Shabrawi, Y., Schmut, O., Jahrbacher, R., et al. (2007) · Ophthalmology · doi:10.1016/j.ophtha.2006.07.048 · Cited by 87
Risk factors for age related maculopathy in a Japanese population: the Hisayama study
Miyazaki, M. (2003) · British Journal of Ophthalmology · doi:10.1136/bjo.87.4.469 · Cited by 87
( R )-α-Lipoic Acid Protects Retinal Pigment Epithelial Cells from Oxidative Damage
Voloboueva, L. A., Liu, J., Suh, J. H., Ames, B. N., & Miller, S. S. (2005) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-1098 · Cited by 87
Ashraf, M., Souka, A., & Adelman, R. A. (2017) · Acta Ophthalmologica · doi:10.1111/aos.13565 · Cited by 86
Pons, M., & Marin‐Castaño, M. E. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016722 · Cited by 87
HTRA1 Variants in Exudative Age-Related Macular Degeneration and Interactions with Smoking and CFH
Tam, P. O. S., Ng, T. K., Liu, D. T. L., Chan, W. M., Chiang, S. W. Y., Chen, L. J., DeWan, A. T., Hoh, J. J., Lam, D. S. C., & Pang, C. P. (2008) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-1520 · Cited by 84
Thomson, L. R., Toyoda, Y., Delori, F. C., Garnett, K. M., Wong, Z.-Y., Nichols, C. R., Cheng, K. M., Craft, N. E., & Dorey, C. K. (2002) · Experimental Eye Research · doi:10.1006/exer.2002.2050 · Cited by 84
Association of neovascular age-related macular degeneration and hyperhomocysteinemia
Axer‐Siegel, R., Bourla, D. H., Ehrlich, R., Dotan, G., Benjamini, Y., Gavendo, S., Weinberger, D., & Sela, B. (2003) · American Journal of Ophthalmology · doi:10.1016/s0002-9394(03)00864-x · Cited by 84
Incidence and Progression of Geographic Atrophy
Joachim, N., Mitchell, P., Kifley, A., Rochtchina, E., Hong, T., & Wang, J. J. (2013) · Ophthalmology · doi:10.1016/j.ophtha.2013.03.029 · Cited by 84
Self-citationSabour‐Pickett, S., Nolan, J. M., Loughman, J., & Beatty, S. (2011) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201100219 · Cited by 85
Laser photocoagulation for neovascular age-related macular degeneration
Virgili, G., & Bini, A. (2007) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004763.pub2 · Cited by 86
Progression of Geographic Atrophy and Genotype in Age-Related Macular Degeneration
Klein, M. L., Ferris, F. L., Francis, P. J., Lindblad, A. S., Chew, E. Y., Hamon, S., & Ott, J. (2010) · Ophthalmology · doi:10.1016/j.ophtha.2009.12.012 · Cited by 84
Chen, Y. (2011) · Archives of Ophthalmology · doi:10.1001/archophthalmol.2011.10 · Cited by 83
Nischler, C., Oberkofler, H., Ortner, C., Paikl, D., Riha, W., Lang, N., Patsch, W., & Egger, S. F. (2011) · Acta Ophthalmologica · doi:10.1111/j.1755-3768.2010.02080.x · Cited by 81
Brinks, J., van Dijk, E. H. C., Klaassen, I., Schlingemann, R. O., Kiełbasa, S. M., Emri, E., Quax, P. H. A., Bergen, A. A. B., Meijer, O. C., & Boon, C. J. F. (2021) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2021.100994 · Cited by 82
Loyet, K. M., DeForge, L. E., Katschke, K. J., Diehl, L. J., Graham, R., Pao, L. I., Sturgeon, L., Lewin-Koh, S.-C., Hollyfield, J. G., & Campagne, M. V. L. (2012) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-9587 · Cited by 84
The use of cholesterol-lowering medications and age-related macular degeneration
McGwin, G., Xie, A., & Owsley, C. J. (2005) · Ophthalmology · doi:10.1016/j.ophtha.2004.10.027 · Cited by 81
Statins for age-related macular degeneration
Gehlbach, P. L., Li, T., & Hatef, E. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd006927.pub3 · Cited by 80
Korb, C. A., Kottler, U. B., Wolfram, C., Höhn, R., Schulz, A., Zwiener, I., Wild, P. S., Pfeiffer, N., & Mirshahi, A. (2014) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-014-2591-9 · Cited by 79
Wang, J. J., Rochtchina, E., Smith, W. T., Klein, R., Klein, B. E. K., Joshi, T., Sivakumaran, T. A., Iyengar, S. K., & Mitchell, P. B. (2008) · American Journal of Epidemiology · doi:10.1093/aje/kwn358 · Cited by 80
Self-citationMacrophages in neovascular age-related macular degeneration: friends or foes?
Skeie, J. M., & Mullins, R. F. (2008) · Eye · doi:10.1038/eye.2008.206 · Cited by 80
Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1
Chinnery, H. R., McLenachan, S., Humphries, T. G., Kezic, J. M., Chen, X., Ruitenberg, M. J., & McMenamin, P. G. (2011) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2011.03.010 · Cited by 82
Strunnikova, N., Zhang, C., Teichberg, D., Cousins, S. W., Baffi, J., Becker, K. G., & Csaky, K. G. (2004) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.04-0311 · Cited by 78
Update of the vascular model of AMD
Friedman, E. (2004) · British Journal of Ophthalmology · doi:10.1136/bjo.2003.036277 · Cited by 78
Exposure to Chlamydia pneumoniae infection and progression of age-related macular degeneration
Robman, L., Mahdi, O., McCarty, C., Dimitrov, P., Tikellis, G., McNeil, J., Byrne, G., Taylor, H., & Guymer, R. (2005) · American Journal of Epidemiology · doi:10.1093/aje/kwi130 · Cited by 77
Choudhury, F., Varma, R., McKean‐Cowdin, R., Klein, R., & Azen, S. P. (2011) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2011.02.025 · Cited by 77
Self-citationDiabetes Mellitus and Visual Impairment
Zhang, X. (2008) · Archives of Ophthalmology · doi:10.1001/archopht.126.10.1421 · Cited by 80
Pons, M., & Marin‐Castaño, M. E. (2011) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.10-6254 · Cited by 77
Aging of the eye: Lessons from cataracts and age-related macular degeneration
Cvekl, A., & Vijg, J. (2024) · Ageing Research Reviews · doi:10.1016/j.arr.2024.102407 · Cited by 77
Schmier, J. K., Halpern, M. T., COVERT, D. W., Delgado, J., & Sharma, S. (2006) · Retina · doi:10.1097/01.iae.0000254890.48272.5a · Cited by 76
Gupta, S., Murthy, G. V. S., Morrison, N., Price, G. M., Dherani, M., John, N., FLETCHER, A. E., & Chakravarthy, U. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-0712 · Cited by 75
Xu, Y.-L., Guan, N., Xu, J., Yang, X., Ma, K., Zhou, H., Zhang, F., Snellingen, T., Jiao, Y., Liu, X., et al. (2008) · Europe PMC (PubMed Central) · Cited by 75
Population-Based Studies in Ophthalmology
Wong, T. Y., & Hyman, L. (2008) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2008.07.048 · Cited by 74
Loss of Complement Factor H impairs antioxidant capacity and energy metabolism of human RPE cells
Armento, A., Honisch, S., Panagiotakopoulou, V., Sonntag, I., Jacob, A., Bolz, S., Kilger, E., Deleidi, M., Clark, S. J., & Ueffing, M. (2020) · Scientific Reports · doi:10.1038/s41598-020-67292-z · Cited by 75
Analysis of the Y402H Variant of the Complement Factor H Gene in Age-Related Macular Degeneration
Baird, P. N., Islam, A. F. M., Richardson, A. J., Cain, M. S., Hunt, N. C., & Guymer, R. H. (2006) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.05-1285 · Cited by 74
Age-Related Macular Degeneration: Insights into Inflammatory Genes
Cascella, R., Ragazzo, M., Strafella, C., Missiroli, F., Borgiani, P., Angelucci, F., Marsella, L., Cusumano, A., Novelli, G., Ricci, F., et al. (2014) · Journal of Ophthalmology · doi:10.1155/2014/582842 · Cited by 74
Bartlett, H., & Eperjesi, F. (2003) · Ophthalmic & physiological optics · doi:10.1046/j.1475-1313.2003.00130.x · Cited by 74
Chakravarthy, U., Bailey, C., Scanlon, P. H., McKibbin, M., Khan, R. S., Mahmood, S., Downey, L., Dhingra, N., Brand, C., Brittain, C. J., et al. (2020) · Ophthalmology Retina · doi:10.1016/j.oret.2020.01.012 · Cited by 71
Cho, B., Heo, J. W., Kim, T. W., Ahn, J., & Chung, H. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-13096 · Cited by 71
Age‐related maculopathy: pathogenetic features and new treatment modalities
Algvere, P. V., & Seregard, S. (2002) · Acta Ophthalmologica Scandinavica · doi:10.1034/j.1600-0420.2002.800204.x · Cited by 71
Association of diabetes with age-related macular degeneration in the EUREYE study
Topouzis, F., Anastasopoulos, E., Augood, C. A., Bentham, G., Chakravarthy, U., de Jong, P. T. V. M., Rahu, M., Seland, J. H., Soubrane, G., Tomazzoli, L., et al. (2009) · British Journal of Ophthalmology · doi:10.1136/bjo.2008.146316 · Cited by 71
Mori, K., Gehlbach, P. L., Kabasawa, S., Kawasaki, I., Oosaki, M., Iizuka, H., Katayama, S., Awata, T., & Yoneya, S. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0426 · Cited by 70
Cuticular drusen: Stars in the sky
Boon, C. J. F., van de Ven, J. P. H., Hoyng, C. B., den Hollander, A. I., & Klevering, B. J. (2013) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2013.08.003 · Cited by 71
Yamada, K., Sakurai, E., Itaya, M., Yamasaki, S., & Ogura, Y. (2007) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.06-1085 · Cited by 70
Augood, C. A., FLETCHER, A. E., Bentham, G., Chakravarthy, U., de Jong, P. T. V. M., Rahu, M., Seland, J. H., Soubrane, G., Tomazzoli, L., Topouzis, F., et al. (2004) · Ophthalmic Epidemiology · doi:10.1076/opep.11.2.117.28160 · Cited by 70
Antioxidant Drug Therapy Approaches for Neuroprotection in Chronic Diseases of the Retina
Payne, A., Kaja, S., Naumchuk, Y., Kunjukunju, N., & Koulen, P. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15021865 · Cited by 70
Boyle, J., Vukicevic, M., Koklanis, K., & Itsiopoulos, C. (2014) · Psychology Health & Medicine · doi:10.1080/13548506.2014.936886 · Cited by 70
Progress in defining the molecular biology of age related macular degeneration
Lotery, A. J., & Trump, D. (2007) · Human Genetics · doi:10.1007/s00439-007-0406-3 · Cited by 71
Ocular Vascular Diseases: From Retinal Immune Privilege to Inflammation
Wang, X., Wang, T., Lam, E., Álvarez, D., & Sun, Y. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512090 · Cited by 71
Radiotherapy for neovascular age-related macular degeneration
Evans, J. R., Sivagnanavel, V., & Chong, V. N. (2010) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004004.pub3 · Cited by 69
Nakayama, M., Iejima, D., Akahori, M., Kamei, J., Goto, A., & Iwata, T. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-14453 · Cited by 69
Ocular Rigidity in Patients With Age-related Macular Degeneration
Pallikaris, I. G., Kymionis, G. D., GINIS, H. S., Kounis, G. A., Christodoulakis, E., & Tsilimbaris, M. K. (2006) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2005.11.010 · Cited by 68
Pachychoroid Geographic Atrophy
Takahashi, A., Ooto, S., Yamashiro, K., Tamura, H., Oishi, A., Miyata, M., Hata, M., Yoshikawa, M., Yoshimura, N., & Tsujikawa, A. (2017) · Ophthalmology Retina · doi:10.1016/j.oret.2017.08.016 · Cited by 68
Martin, D. F., Bressler, N. M., Bressler, S. B., Chew, E. Y., Clemons, T. E., Klein, R., & Seddon, J. M. (2003) · Investigative Ophthalmology & Visual Science · Cited by 68
Self-citationGenetics and genetic testing for age-related macular degeneration
Warwick, A., & Lotery, A. (2018) · Eye · doi:10.1038/eye.2017.245 · Cited by 67
Recent developments in the management of dry age-related macular degeneration
Buschini, E., Zola, M., Fea, A. M., Lavia, C. A., Nassisi, M., Pignata, G., & Grignolo, F. M. (2015) · Clinical ophthalmology · doi:10.2147/opth.s59724 · Cited by 67
Toma, C., Cillà, S. D., Palumbo, A., Garhwal, D. P., & Grossini, E. (2021) · Antioxidants · doi:10.3390/antiox10050653 · Cited by 67
Cano, M., Datta, S., Wang, L., Liu, T., Flores‐Bellver, M., Sachdeva, M. M., Sinha, D., & Handa, J. T. (2021) · Aging Cell · doi:10.1111/acel.13444 · Cited by 66
Seitsonen, S., Onkamo, P., Peng, G., Xiong, M., Tommila, P. V., Ranta, P., Holopainen, J. M., Moilanen, J., Palosaari, T., Kaarniranta, K., et al. (2008) · PLoS ONE · doi:10.1371/journal.pone.0003833 · Cited by 66
Freeman, S., Kozak, I., Cheng, L., Bartsch, D., Mojana, F., Nigam, N., Brar, M., Yuson, R. M. S., & Freeman, W. R. (2010) · Retina · doi:10.1097/iae.0b013e3181bd2f94 · Cited by 67
Simonelli, F. (2006) · British Journal of Ophthalmology · doi:10.1136/bjo.2006.096487 · Cited by 66
Hopley, C. (2004) · British Journal of Ophthalmology · doi:10.1136/bjo.2003.035279 · Cited by 66
Age-Related Macular Degeneration: Clinical Findings, Histopathology and Imaging Techniques
Zarbin, M. A., Casaroli-Marano, R. P., & Rosenfeld, P. J. (2014) · Developments in ophthalmology · doi:10.1159/000358536 · Cited by 66
Effect of dietary zeaxanthin on tissue distribution of zeaxanthin and lutein in quail.
Toyoda, Y., Thomson, L. R., Langner, A., Craft, N. E., Garnett, K. M., Nichols, C. R., Cheng, K. M., & Dorey, C. K. (2002) · PubMed · Cited by 64
Ling, C. N. Y., Lim, S. C., Jonas, J. B., & Sabanayagam, C. (2021) · International Journal of Obesity · doi:10.1038/s41366-021-00829-y · Cited by 65
Different Therapeutic Approaches for Dry and Wet AMD
Marchesi, N., Capierri, M., Pascale, A., & Barbieri, A. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252313053 · Cited by 66
Prevalence and Pattern of Geographic Atrophy in Asia
Rim, T. H., Kawasaki, R., Tham, Y. C., Kang, S. W., Ruamviboonsuk, P., Bikbov, M. M., Miyake, M., Hao, J., FLETCHER, A. E., Sasaki, M., et al. (2020) · Ophthalmology · doi:10.1016/j.ophtha.2020.04.019 · Cited by 63
Pollreisz, A., Reiter, G. S., Bogunović, H., Baumann, L., Jakob, A., Schlanitz, F. G., Sacu, S., Owsley, C. J., Sloan, K. R., Curcio, C. A., et al. (2021) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.62.2.26 · Cited by 62
The role of epigenetics in age-related macular degeneration
Gemenetzi, M. K., & Lotery, A. J. (2014) · Eye · doi:10.1038/eye.2014.225 · Cited by 63
The Association of Aspirin Use With Age-Related Macular Degeneration
Liew, G., Mitchell, P., Wong, T. Y., Rochtchina, E., & Wang, J. J. (2013) · JAMA Internal Medicine · doi:10.1001/jamainternmed.2013.1583 · Cited by 62
Self-citationHMG CoA Reductase Inhibitors (Statins): Do They Have a Role in Age-related Macular Degeneration?
Guymer, R. H., Chiu, A. W.-I., Lim, L. L., & Baird, P. N. (2005) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2004.12.002 · Cited by 61
Schmidt, S., Scott, W. K., Postel, E. A., Agarwal, A., Hauser, E. R., De La Paz, M. A., Gilbert, J. R., Weeks, D. E., Gorin, M. B., Haines, J. L., et al. (2004) · BMC Genetics · doi:10.1186/1471-2156-5-18 · Cited by 60
Sharma, A., Neekhra, A., Gramajo, A. L., Patil, J., Chwa, M., Kuppermann, B. D., & Kenney, M. C. (2008) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.08-2060 · Cited by 60
Hjelmqvist, L., Lindberg, C., Kanulf, P., Dahlgren, H., Johansson, I., & Siewert, A. (2011) · Journal of Ophthalmology · doi:10.1155/2011/405724 · Cited by 61
AMD and micronutrient antioxidants
Hogg, R. E., & Chakravarthy, U. (2004) · Current Eye Research · doi:10.1080/02713680490517890 · Cited by 59
Mecamylamine Suppresses Basal and Nicotine-Stimulated Choroidal Neovascularization
Kiuchi, K., Matsuoka, M., Wu, J., Silva, R. L. E., Kengatharan, M., Mary, V., Ueno, S., Yokoi, K., Khu, N. H., Cooke, J. P., et al. (2008) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0089 · Cited by 60
Treder, M., Lauermann, J. L., & Eter, N. (2018) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-018-4098-2 · Cited by 58
Optimization of pillar electrodes in subretinal prosthesis for enhanced proximity to target neurons
Flores, T., Lei, X., Huang, T., Lorach, H., Dalal, R., Galambos, L., Kamins, T., Mathieson, K., & Palanker, D. (2018) · Journal of Neural Engineering · doi:10.1088/1741-2552/aaac39 · Cited by 57
Munch, I. C., Linneberg, A. R., & Larsen, M. (2013) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.12-10785 · Cited by 57
Preventing and Managing Visual Disability in Primary Care
Goldzweig, C. L., Rowe, S. G., Wenger, N. S., MacLean, C. H., & Shekelle, P. (2004) · JAMA · doi:10.1001/jama.291.12.1497 · Cited by 58
Dow, C. T., & Harley, C. (2016) · Clinical Ophthalmology · doi:10.2147/opth.s100042 · Cited by 56
Alcazar, O., Cousins, S. W., Striker, G. E., & Marin‐Castaño, M. E. (2009) · Experimental Eye Research · doi:10.1016/j.exer.2009.06.014 · Cited by 56
Cardiovascular risk factors associated with age‐related macular degeneration: the Tromsø Study
Erke, M. G., Bertelsen, G., Pető, T., Sjølie, A. K., Lindekleiv, H., & Njølstad, I. (2014) · Acta Ophthalmologica · doi:10.1111/aos.12346 · Cited by 56
Spatiotemporal characteristics of retinal response to network-mediated photovoltaic stimulation
Ho, E., Smith, R., Goetz, G., Lei, X., Galambos, L., Kamins, T. I., Harris, J. S., Mathieson, K., Palanker, D., & Sher, A. (2017) · Journal of Neurophysiology · doi:10.1152/jn.00872.2016 · Cited by 57
High density lipoprotein mediated lipid efflux from retinal pigment epithelial cells in culture
Ishida, B. Y. (2006) · British Journal of Ophthalmology · doi:10.1136/bjo.2005.085076 · Cited by 56
Vassilev, Z. P., Ruigómez, A., Soriano‐Gabarró, M., & Rodriguez, L. A. G. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-16271 · Cited by 55
Joint effects of smoking history and APOE genotypes in age-related macular degeneration.
Schmidt, S., Haines, J. L., Postel, E. A., Agarwal, A., Kwan, S. Y., Gilbert, J. R., Pericak‐Vance, M. A., & Scott, W. K. (2005) · PubMed · Cited by 55
The Blue Light Hazard Versus Blue Light Hype
Mainster, M. A., Findl, O., Dick, H. B., Desmettre, T. J., Ledesma‐Gil, G., Curcio, C. A., & Turner, P. L. (2022) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2022.02.016 · Cited by 54
Genomic aspects of age-related macular degeneration
Horie‐Inoue, K., & Inoue, S. (2014) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2014.08.013 · Cited by 54
Coleman, A. L., Yu, F., Ensrud, K. E., Stone, K. L., Cauley, J. A., Pedula, K. L., Hochberg, M. C., & Mangione, C. M. (2010) · American Journal of Ophthalmology · doi:10.1016/j.ajo.2010.05.030 · Cited by 56
Parmar, V. M., Parmar, T., Arai, E., Perusek, L., & Maeda, A. (2018) · Stem Cell Research · doi:10.1016/j.scr.2018.01.014 · Cited by 54
The Role of the Complement System in Age-Related Macular Degeneration
Weber, B. H. F., Issa, P. C., Pauly, D., Herrmann, P., Graßmann, F., & Holz, F. G. (2014) · Deutsches Ärzteblatt international · doi:10.3238/arztebl.2014.0133 · Cited by 55
Rare Complement Factor H Variant Associated With Age-Related Macular Degeneration in the Amish
Hoffman, J., Bailey, J. N. C., D’Aoust, L. N., Cade, W., Ayala-Haedo, J., Fuzzell, D., Laux, R. A., Adams, L. D., Reinhart‐Mercer, L., Caywood, L. J., et al. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.13-13684 · Cited by 53
Zinc Supplementation Inhibits Complement Activation in Age-Related Macular Degeneration
Smailhodzic, D., van Asten, F., Blom, A. M., Mohlin, F. C., den Hollander, A. I., van de Ven, J. P. H., van Huet, R. A. C., Groenewoud, J. M. M., Tian, Y., Berendschot, T. T. J. M., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0112682 · Cited by 54
Kumar, N., Mrejen, S., Fung, A. T.-C., Marsiglia, M., Loh, B. K., & Spaide, R. F. (2012) · Ophthalmology · doi:10.1016/j.ophtha.2012.07.076 · Cited by 53
Kim, E. C., Han, K., & Jee, D. (2014) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.14-14763 · Cited by 53
Brétillon, L., Acar, N., Seeliger, M. W., Santos, M., Maire, M. A., ́da, P. J., Martine, L., Gregoire, S., Joffre, C., Bron, A. M., et al. (2008) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.07-0808 · Cited by 53
Metadata
- Authors
- Smith, W., Assink, J., Klein, R., Mitchell, P., Klaver, C. C. W., Klein, B. E. K., Hofman, A., Jensen, S., Wang, J. J., & de Jong, P. T. V. M.
- Affiliations
- Australian National University (AU)
- Erasmus University Rotterdam (NL)
- The University of Sydney (AU)
- University of Wisconsin–Madison (US)
- Corresponding author
- Mitchell, Paul
- Venue
- Ophthalmology
- Publisher
- Elsevier BV
- Published
- 2001-04
- Volume
- 108
- Issue
- 4
- Pages
- 697-704
- ISSN
- 0161-6420 (ISSN-L)
- OpenAlex
- W1543801259
- Cited by
- 1,071
- References
- 43
- Citations by year
- 2026: 12 · 2025: 30 · 2024: 43 · 2023: 33 · 2022: 44 · 2021: 51 · 2020: 30 · 2019: 28 · 2018: 33 · 2017: 43 · 2016: 43 · 2015: 46 · 2014: 70 · 2013: 52 · 2012: 60
- FWCI
- 11.39
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Ophthalmology (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Topics
- Health Sciences › Medicine › Ophthalmology › Retinal Diseases and Treatments
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Retinal Imaging and Analysis
- Health Sciences › Medicine › Ophthalmology › Ocular Diseases and Behçet’s Syndrome
- Keywords
- age-related macular degeneration, neovascular AMD, geographic atrophy, prevalence, risk factors, smoking, age, gender differences, Beaver Dam Eye Study, Rotterdam Study, Blue Mountains Eye Study, cross-population comparison
- MeSH terms
- Adult, Aged, Aged, 80 and over, Female, Humans, Macular Degeneration, Male, Middle Aged, Netherlands, New South Wales, Risk Factors, Smoking, Wisconsin, Prevalence, Age Distribution, Sex Distribution
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
