Comparison of dopamine and noradrenaline release in mouse prefrontal cortex, striatum and hippocampus using microdialysis
Abstract
In vivo release of dopamine (DA) and noradrenaline (NA) in mouse medial prefrontal cortex, medial striatum and hippocampus was characterized using in vivo microdialysis. Basal release of NA was similar in these areas, but DA in striatum was 13-30 times higher than in other areas. Unconditioned stimuli (handling, novelty) induced strong increases, except for striatal DA. Striatal NA was more sensitive to handling than NA in other areas.
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Placing a rat in a novel environment leads to dopamine release in the hippocampus.
“Placing a rat in a novel environment leads to dopamine release in the hippocampus [19]”
From A neoHebbian framework for episodic memory; role of dopamine-dependent late LTP (2011) · cites this paper as [19]
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- Authors
- Ihalainen, J. A., Riekkinen Jr, P., & Feenstra, M. G. P.
- Affiliations
- Kuopio University Hospital (FI)
- Corresponding author
- Feenstra, M.G.P
- Venue
- Neuroscience Letters
- Publisher
- Elsevier BV
- Published
- 1999-12
- Volume
- 277
- Issue
- 2
- Pages
- 71-74
- ISSN
- 0304-3940 (ISSN-L)
- OpenAlex
- W2079911317
- Cited by
- 148
- References
- 21
- Citations by year
- 2025: 3 · 2024: 16 · 2023: 1 · 2022: 6 · 2021: 4 · 2020: 6 · 2019: 3 · 2018: 12 · 2017: 7 · 2016: 9 · 2015: 8 · 2014: 12 · 2013: 6 · 2012: 3
- FWCI
- 1.09
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuroscience Letters (publishedVersion)
- PubMed (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Keywords
- dopamine release, noradrenaline release, prefrontal cortex, striatum, hippocampus, handling stress, novelty, unconditioned stimulus
- MeSH terms
- Animals, Corpus Striatum, Dopamine, Handling, Psychological, Hippocampus, Male, Mice, Inbred C57BL, Norepinephrine, Prefrontal Cortex, Microdialysis, Mice
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