Weight management strategies for patients with PCOS: current perspectives
Abstract
INTRODUCTION: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive-aged women. Overweight and obesity commonly accompany the syndrome at the clinic and are significant concerns for women with PCOS. AREAS COVERED: Herein, we provide an overview of the relevant literature on weight management strategies in women with PCOS. We performed an electronic-based search using PubMed until February 2021. We aimed to summarize available evidence of different weight-reducing interventions in PCOS and outline the gaps in our current knowledge and recommend areas for further research. EXPERT OPINION: PCOS is closely linked to obesity and increased adiposity enhances severity and expression of PCOS phenotype. Current data suggest that weight loss is associated with improved metabolic, endocrine, reproductive, cardiovascular and psychological features in overweight and obese women with PCOS. Lifestyle interventions including diet and exercise, anti-obesity medications and bariatric surgery have been used as therapeutic approaches for short-term management of obesity in PCOS with varying success rates. Large and sufficiently powered studies are required in order to determine long-term effects of weight management strategies and potential benefits beyond weight loss in the syndrome. This would allow informing the guidelines to make PCOS specific evidence-based recommendations.
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Weight loss through diet, physical activity, and lifestyle changes in women with PCOS, especially those with obesity, can improve metabolic parameters, reduce the risk of type 2 diabetes, lower triglycerides, enhance insulin sensitivity, normalize hormone levels, alleviate symptoms like hirsutism and acne, and support ovarian function and menstrual regularity.
“Weight loss through diet, physical activity, and lifestyle changes in women with PCOS, especially those with obesity, can improve metabolic parameters, reduce the risk of type 2 diabetes, lower triglycerides, and enhance insulin sensitivity. It also helps normalize hormone levels, alleviating symptoms like hirsutism and acne, supports ovarian function and menstrual regularity [36].”
From Dietary Patterns and Metabolic and Hormonal Parameters in Women with Suspected PCOS (2025) · cites this paper as [36]
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INOVAÇÕES NO MANEJO CLÍNICO DA SÍNDROME DO OVÁRIO POLICÍSTICO – UMA REVISÃO INTEGRATIVA
Sepulbeda, G. A. A., Sepulbeda, C. F. A., Junqueira, S. C. A., Rocha, B. L. D., Alciati, J. G. G., Mamani, A. J. L., & Maron, Y. L. (2026) · RECIMA21 - Revista Científica Multidisciplinar · doi:10.47820/recima21.v7i7.8298
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- Authors
- Ozgen Saydam, B., & Yildiz, B. O.
- Affiliations
- Yildirim Beyazit University, Yenimahalle Training and Research Hospital, Division of Endocrinology and Metabolism, Ankara, Turkey
- Hacettepe University School of Medicine, Division of Endocrinology and Metabolism, Ankara, Turkey
- Venue
- Expert Review of Endocrinology & Metabolism
- Publisher
- Informa UK Limited
- Published
- 2021-03-04
- Volume
- 16
- Issue
- 2
- Pages
- 49-62
- ISSN
- 1744-6651 (ISSN-L)
- 1744-8417
- OpenAlex
- W3135023887
- Cited by
- 33
- References
- 104
- Citations by year
- 2026: 9 · 2025: 9 · 2024: 4 · 2023: 6 · 2022: 4 · 2021: 1
- FWCI
- 0.62
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Expert Review of Endocrinology & Metabolism (publishedVersion)
- PubMed (publishedVersion)
- AYBU AVESIS (submittedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Obesity, Physical Activity, Diet
- Keywords
- polycystic ovary syndrome, weight management, obesity, weight loss interventions, lifestyle intervention, diet and exercise, anti-obesity drugs, bariatric surgery, adiposity
- MeSH terms
- Adult, Female, Humans, Life Style, Obesity, Polycystic Ovary Syndrome, Weight Loss, Overweight
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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