Poly(glycerol sebacate urethane)–cellulose nanocomposites with water-active shape-memory effects
Abstract
Biodegradable and biocompatible materials with shape-memory effects (SMEs) are attractive for use as minimally invasive medical devices. Nanocomposites with SMEs were prepared from biodegradable poly(glycerol sebacate urethane) (PGSU) and renewable cellulose nanocrystals (CNCs). The effects of CNC content on the structure, water absorption, and mechanical properties of the PGSU were studied. The water-responsive mechanically adaptive properties and shape-memory performance of PGSU-CNC nanocomposites were observed, which are dependent on the content of CNCs. The PGSU-CNC nanocomposite containing 23.2 vol % CNCs exhibited the best SMEs among the nanocomposites investigated, with the stable shape fixing and shape recovery ratios being 98 and 99%, respectively, attributable to the formation of a hydrophilic, yet strong, CNC network in the elastomeric matrix. In vitro degradation profiles of the nanocomposites were assessed with and without the presence of an enzyme.
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The presence of CNCs up to 23 vol% improved PGSU tensile strength and Young's modulus up to 1040% and 4400%, respectively.
“The presence of CNCs (up to 23 vol%) led to an improvement of the PGSU materials tensile strength and the Young's modulus up to 1040% and 4400%, respectively.”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
In the PGSU-CNC study, hydrophilic nanocrystals were grafted along the polymer macromolecule via reaction of CNCs with isocyanate groups of hexamethylene diisocyanate to form urethane linkages.
“In this study the hydrophilic nanocrystals were grafted along the polymer macromolecule: CNCs got competed with the -OH groups from PGS prepolymer (product of glycerol and sebacic acid polycondensation) to react with the isocyanate groups of hexamethylene diisocyanate in order to form urethane linkages.”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
Water-active shape-memory materials using hydrophilic CNCs as an active agent were prepared using biodegradable poly(glycerol sebacate urethane) (PGSU).
“hydrophilic CNCs as an active agent, were also prepared using biodegradable poly(glycerol sebacate urethane) (PGSU) [185].”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
The improvement was explained by formation of strong interfacial hydrogen-bond interactions between CNCs and PGSU in the blend.
“The phenomena was explained with the formation of strong interfacial interactions based on hydrogen bonds between CNCs and PGSU in the blend.”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
PGSU-CNC materials were lipase enzymatically degradable, with weight loss of 17% in 28 days.
“The materials were lipase enzymatically degradable (weight loss of 17% in 28 days)”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
Shape fixity and shape recovery ratios of PGSU-CNC nanocomposites increased with CNCs content and became stable at Rr 98% and Rf 99% after the first three wetting-stretching-drying cycles, owing to elimination of sample processing history and CNCs alignment.
“The shape fixity and shape recovery ratios of the PGSU-CNC nanocomposites increased with the CNCs content and became stable (Rr 98% and Rf 99%) after the first three wetting-stretching-drying cycles, owing to the elimination of the sample processing history and CNCs alignment.”
From Shape-memory polymers for multiple applications in the materials world (2016) · cites this paper as [185]
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- Authors
- Wu, T., Frydrych, M., O’Kelly, K., & Chen, B.
- Affiliations
- University of Sheffield (GB)
- Trinity College Dublin (IE)
- Corresponding author
- Chen, Biqiong
- Venue
- Biomacromolecules
- Publisher
- American Chemical Society (ACS)
- Published
- 2014-06-10
- Volume
- 15
- Issue
- 7
- Pages
- 2663-2671
- ISSN
- 1525-7797 (ISSN-L)
- 1526-4602
- OpenAlex
- W2328964456
- Cited by
- 126
- References
- 79
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 10 · 2023: 9 · 2022: 11 · 2021: 14 · 2020: 11 · 2019: 15 · 2018: 14 · 2017: 12 · 2016: 12 · 2015: 8
- FWCI
- 7.45
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Biomacromolecules (publishedVersion)
- PubMed (publishedVersion)
- Research Portal (Queen's University Belfast) (submittedVersion)
- Funders
- Royal Society
- Irish Research Council for Science, Engineering and Technology
- Topics
- Physical Sciences › Materials Science › Polymers and Plastics › Polymer composites and self-healing
- Physical Sciences › Engineering › Mechanical Engineering › Advanced Materials and Mechanics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Keywords
- cellulose nanocrystals, shape memory effect, water-responsive materials, biodegradable polymers, nanocomposites, water absorption, mechanical properties, shape recovery ratio, enzymatic degradation, minimally invasive medical devices
- MeSH terms
- Biocompatible Materials, Cellulose, Decanoic Acids, Elasticity, Glycerol, Lipase, Polymers, Polyurethanes, Surface Properties, Tensile Strength, Absorbable Implants, Nanoparticles, Nanocomposites, Hydrophobic and Hydrophilic Interactions
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