Cited by 502

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Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation

Van Roey, Kim, Uyar, Bora, Weatheritt, Robert J., Dinkel, Holger, Seiler, Markus, Budd, Aidan, Gibson, Toby J., Davey, Norman E.·2014·Chemical Reviews

DOI 10.1021/cr400585q

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Abstract

The eukaryotic cell is a bustling collection of macromolecules acting cooperatively to mediate the functions required for cell viability. Specific, context-dependent and tightly controlled physical interactions between these cellular components govern the necessary physiological processes, from cell division to cell death. The specificity, conditionality, and regulation of these binding events depend on communication between the interacting molecules and their surroundings. For proteins, most of this communication is mediated by a variety of modules that are embedded within the protein sequence, can bind a wide array of ligands, and have catalytic, regulatory, or scaffolding activity. These functional units enable proteins to sense, integrate, and transmit environmental and cell state indicators and concomitantly instigate cellular decisions based on the information available to the system.

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Global quantification of mammalian gene expression control
Schwanhäusser, B., Busse, D., Li, N., Dittmar, G., Schuchhardt, J., Wolf, J., Chen, W., & Selbach, M. (2011) · Nature · doi:10.1038/nature10098 · Cited by 6,566
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., et al. (2004) · Science · doi:10.1126/science.1092472 · Cited by 4,661
Intrinsically unstructured proteins and their functions
Dyson, H. J., & Wright, P. E. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1589 · Cited by 3,871
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
Cho, Y., Gorina, S., Jeffrey, P. D., & Pavletich, N. P. (1994) · Science · doi:10.1126/science.8023157 · Cited by 2,551
Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain
Kussie, P. H., Gorina, S., Marechal, V., Elenbaas, B., Moreau, J., Levine, A. J., & Pavletich, N. P. (1996) · Science · doi:10.1126/science.274.5289.948 · Cited by 2,206
A signature motif in transcriptional co-activators mediates binding to nuclear receptors
Heery, D. M., Kalkhoven, E., Hoare, S., & Parker, M. G. (1997) · Nature · doi:10.1038/42750 · Cited by 2,128
Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels
Kato, M., Han, T. W., Xie, S., Shi, K., Du, X., Wu, L. C., Mirzaei, H., Goldsmith, E. J., Longgood, J., Pei, J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.04.017 · Cited by 2,012
Mechanism of auxin perception by the TIR1 ubiquitin ligase
Tan, X., Calderon-Villalobos, L. I. A., Sharon, M., Zheng, C., Robinson, C. V., Estelle, M., & Zheng, N. (2007) · Nature · doi:10.1038/nature05731 · Cited by 1,688
An h Per2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome
Toh, K. L., Jones, C. R., He, Y., Eide, E. J., Hinz, W. A., Virshup, D. M., Ptáček, L. J., & Fu, Y.-H. (2001) · Science · doi:10.1126/science.1057499 · Cited by 1,460
CDK inhibitors: Cell cycle regulators and beyond
Besson, A., Dowdy, S. F., & Roberts, J. M. (2008) · Developmental Cell · doi:10.1016/j.devcel.2008.01.013 · Cited by 1,152
Curvature of clathrin-coated pits driven by epsin
Ford, M. G. J., Mills, I. G., Peter, B. J., Vallis, Y., Praefcke, G. J. K., Evans, P. R., & McMahon, H. T. (2002) · Nature · doi:10.1038/nature01020 · Cited by 1,019
A conserved docking motif in MAP kinases common to substrates, activators and regulators
Tanoue, T., Adachi, M., Moriguchi, T., & Nishida, E. (2000) · Nature Cell Biology · doi:10.1038/35000065 · Cited by 816
Substrate Specificities and Identification of Putative Substrates of ATM Kinase Family Members
Kim, S.-T., Lim, D.-S., Canman, C. E., & Kastan, M. B. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.53.37538 · Cited by 810
Structural basis for the recognition of hydroxyproline in HIF-1α by pVHL
Hon, W.-C., Wilson, M. I., Harlos, K., Claridge, T. D. W., Schofield, C. J., Pugh, C. W., Maxwell, P. H., Ratcliffe, P. J., Stuart, D. I., & Jones, E. Y. (2002) · Nature · doi:10.1038/nature00767 · Cited by 751
A common human skin tumour is caused by activating mutations in β-catenin
Chan, E., Gat, U., McNiff, J. M., & Fuchs, E. (1999) · Nature Genetics · doi:10.1038/7747 · Cited by 612
Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study
Ray-Coquard, I., Blay, J.-Y., Italiano, A., Le Cesne, A., Penel, N., Zhi, J., Heil, F., Rueger, R., Graves, B., Ding, M., et al. (2012) · The Lancet Oncology · doi:10.1016/s1470-2045(12)70474-6 · Cited by 571
Transcriptional Regulation by P53
Beckerman, R., & Prives, C. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000935 · Cited by 569
Targeting the von Hippel-Lindau E3 ubiquitin ligase using small molecules to disrupt the VHL/HIF-1α interaction
Buckley, D. L., Van Molle, I., Gareiss, P. C., Tae, H. S., Michel, J., Noblin, D. J., Jorgensen, W. L., Ciulli, A., & Crews, C. M. (2012) · Journal of the American Chemical Society · doi:10.1021/ja209924v · Cited by 569
The updated biology of hypoxia-inducible factor
Greer, S. N., Metcalf, J. L., Wang, Y., & Ohh, M. (2012) · The EMBO Journal · doi:10.1038/emboj.2012.125 · Cited by 545
Tissue-specific splicing of disordered segments that embed binding motifs rewires protein interaction networks
Buljan, M., Chalancon, G., Eustermann, S., Wagner, G. P., Fuxreiter, M., Bateman, A., & Babu, M. M. (2012) · Molecular Cell · doi:10.1016/j.molcel.2012.05.039 · Cited by 396
Linear motifs: Evolutionary interaction switches
Neduva, V., & Russell, R. B. (2005) · FEBS Letters · doi:10.1016/j.febslet.2005.04.005 · Cited by 352
HIF-1 regulation: not so easy come, easy go
Koh, M. Y., Spivak-Kroizman, T. R., & Powis, G. (2008) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2008.08.002 · Cited by 339
Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactions
BIONDI, R. M., & NEBREDA, A. R. (2003) · Biochemical Journal · doi:10.1042/bj20021641 · Cited by 334
Molecular recognition of p53 and MDM2 by USP7/HAUSP.
Sheng, Y., Saridakis, V., Sarkari, F., Duan, S., Wu, T., Arrowsmith, C. H., & Frappier, L. (2006) · Nature Structural & Molecular Biology · doi:10.1038/nsmb1067 · Cited by 315
Structural Basis of Competitive Recognition of p53 and MDM2 by HAUSP/USP7: Implications for the Regulation of the p53–MDM2 Pathway
Hu, M., Gu, L., Li, M., Jeffrey, P. D., Gu, W., & Shi, Y. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040027 · Cited by 251
Protein Family Expansions and Biological Complexity
Vogel, C., & Chothia, C. (2006) · PLoS Computational Biology · doi:10.1371/journal.pcbi.0020048 · Cited by 227
p53 regulation by ubiquitin
Brooks, C. L., & Gu, W. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.05.022 · Cited by 186
Domain size distributions can predict domain boundaries
Wheelan, S. J., Marchler-Bauer, A., & Bryant, S. H. (2000) · Bioinformatics · doi:10.1093/bioinformatics/16.7.613 · Cited by 182
Auxin Perception--Structural Insights
Calderon-Villalobos, L. I., Tan, X., Zheng, N., & Estelle, M. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005546 · Cited by 177
Membrane Topology of the ATP Binding Cassette Transporter ABCR and Its Relationship to ABC1 and Related ABCA Transporters
Bungert, S., Molday, L. L., & Molday, R. S. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m101902200 · Cited by 173
Multiple degradation pathways regulate versatile CIP/KIP CDK inhibitors
Starostina, N. G., & Kipreos, E. T. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2011.10.004 · Cited by 147
Substrate and Docking Interactions in Serine/Threonine Protein Kinases
Goldsmith, E. J., Akella, R., Min, X., Zhou, T., & Humphreys, J. M. (2007) · Chemical Reviews · doi:10.1021/cr068221w · Cited by 143
β-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases
Kanemori, Y., Uto, K., & Sagata, N. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0501873102 · Cited by 128
Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis
Percy, M. J., Beer, P. A., Campbell, G., Dekker, A. W., Green, A. R., Oscier, D., Rainey, M. G., van Wijk, R., Wood, M., Lappin, T. R. J., et al. (2008) · Blood · doi:10.1182/blood-2008-02-137703 · Cited by 127
Novel Selective Inhibitors of the Interaction of Individual Nuclear Hormone Receptors with a Mutually Shared Steroid Receptor Coactivator 2
Geistlinger, T. R., & Guy, R. K. (2003) · Journal of the American Chemical Society · doi:10.1021/ja0348391 · Cited by 94
Erythrocytosis-associated HIF-2α Mutations Demonstrate a Critical Role for Residues C-terminal to the Hydroxylacceptor Proline
Furlow, P. W., Percy, M. J., Sutherland, S., Bierl, C., McMullin, M. F., Master, S. R., Lappin, T. R. J., & Lee, F. S. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m808737200 · Cited by 58
Further insight into substrate recognition by USP7: structural and biochemical analysis of the HdmX and Hdm2 interactions with USP7.
Sarkari, F., La Delfa, A., Arrowsmith, C. H., Frappier, L., Sheng, Y., & Saridakis, V. (2010) · Journal of Molecular Biology · doi:10.1016/j.jmb.2010.08.017 · Cited by 54
Two new mutations in the HIF2A gene associated with erythrocytosis
Percy, M. J., Chung, Y. J., Harrison, C., Mercieca, J., Hoffbrand, A. V., Dinardo, C. L., Santos, P. C. J. L., Fonseca, G. H. H., Gualandro, S. F. M., Pereira, A. C., et al. (2012) · American Journal of Hematology · doi:10.1002/ajh.23123 · Cited by 37

Research works printed but not linked: 468

Kersse K., 2011, Trends Biochem. Sci., 36, 541, 10.1016/j.tibs.2011.06.006 · DOI
Havugimana P. C., 2012, Cell, 150, 1068, 10.1016/j.cell.2012.08.011 · DOI
Dunker A. K., 2001, J. Mol. Graphics Modell., 19, 26, 10.1016/S1093-3263(00)00138-8 · DOI · Paper page
Wright P. E., 1999, J. Mol. Biol., 293, 321, 10.1006/jmbi.1999.3110 · DOI · Paper page
Uversky V. N., 2000, Proteins, 41, 415, 10.1002/1097-0134(20001115)41:3<415::AID-PROT130>3.0.CO;2-7 · DOI
Tompa P., 2002, Trends Biochem. Sci., 27, 527, 10.1016/S0968-0004(02)02169-2 · DOI · Paper page
Xie H., 2007, J. Proteome Res., 6, 1882, 10.1021/pr060392u · DOI · Paper page
Galea C. A., 2008, Biochemistry, 47, 7598, 10.1021/bi8006803 · DOI
Gsponer J., 2009, Prog. Biophys. Mol. Biol., 99, 94, 10.1016/j.pbiomolbio.2009.03.001 · DOI
Gibson T. J., 2009, Trends Biochem. Sci., 34, 471, 10.1016/j.tibs.2009.06.007 · DOI
Tompa P., 2011, Curr. Opin. Struct. Biol., 21, 419, 10.1016/j.sbi.2011.03.012 · DOI · Paper page
Babu M. M., 2011, Curr. Opin. Struct. Biol., 21, 432, 10.1016/j.sbi.2011.03.011 · DOI · Paper page
Tompa P., 2012, Trends Biochem. Sci., 37, 509, 10.1016/j.tibs.2012.08.004 · DOI · Paper page
Dinkel H., 2014, Nucleic Acids Res., 42, D259, 10.1093/nar/gkt1047 · DOI · Paper page
Davey N. E., 2012, Mol. Biosyst., 8, 268, 10.1039/C1MB05231D · DOI · Paper page
Mohan A., 2006, J. Mol. Biol., 362, 1043, 10.1016/j.jmb.2006.07.087 · DOI · Paper page
Mi T., 2012, Nucleic Acids Res., 40, D252, 10.1093/nar/gkr1189 · DOI
Van Roey K., 2013, Sci. Signal, 6, rs7, 10.1126/scisignal.2003345 · DOI
Beltrao P., 2012, Cell, 150, 413, 10.1016/j.cell.2012.05.036 · DOI
Dinkel H., 2011, Nucleic Acids Res., 39, D261, 10.1093/nar/gkq1104 · DOI · Paper page
Hornbeck P. V., 2012, Nucleic Acids Res., 40, D261, 10.1093/nar/gkr1122 · DOI · Paper page
Zhao Y., 2009, Proteomics, 9, 4632, 10.1002/pmic.200900398 · DOI · Paper page
Stein A., 2011, Nucleic Acids Res., 39, D718, 10.1093/nar/gkq962 · DOI
Schuster-Bockler B., 2007, BMC Bioinformatics, 8, 259, 10.1186/1471-2105-8-259 · DOI
Liddington R. C., 2004, Methods Mol. Biol., 261, 3
Uversky V. N., 2011, Chem. Soc. Rev., 40, 1623, 10.1039/C0CS00057D · DOI · Paper page
Tompa P., 2009, Bioessays, 31, 328, 10.1002/bies.200800151 · DOI
Pornillos O., 2010, J. Mol. Biol., 401, 985, 10.1016/j.jmb.2010.06.042 · DOI
Russo A. A., 1996, Nature, 382, 325, 10.1038/382325a0 · DOI · Paper page
Wu G., 2000, Science, 287, 92, 10.1126/science.287.5450.92 · DOI · Paper page
He J., 2013, Mol. Cell, 50, 649, 10.1016/j.molcel.2013.04.024 · DOI
Jeffrey P. D., 1995, Science, 267, 1498, 10.1126/science.7878469 · DOI · Paper page
Vanhooke J. L., 2004, Biochemistry, 43, 4101, 10.1021/bi036056y · DOI
Wu X., 1995, Structure, 3, 215, 10.1016/S0969-2126(01)00151-4 · DOI
Fontes M. R., 2003, Biochem. J., 375, 339, 10.1042/bj20030510 · DOI
Han J. H., 2007, Nat. Rev. Mol. Cell Biol., 8, 319, 10.1038/nrm2144 · DOI · Paper page
Follis A. V., 2012, Adv. Exp. Med. Biol., 725, 27, 10.1007/978-1-4614-0659-4_3 · DOI
Phan A. T., 2011, Nat. Struct. Mol. Biol., 18, 796, 10.1038/nsmb.2064 · DOI · Paper page
Kojima C., 2004, EMBO J., 23, 4413, 10.1038/sj.emboj.7600442 · DOI
Stein A., 2008, PLoS One, 3, e2524, 10.1371/journal.pone.0002524 · DOI
Chica C., 2009, PLoS One, 4, e6052, 10.1371/journal.pone.0006052 · DOI
London N., 2010, Structure, 18, 188, 10.1016/j.str.2009.11.012 · DOI · Paper page
Kalderon D., 1984, Cell, 39, 499, 10.1016/0092-8674(84)90457-4 · DOI
Kastritis P. L., 2011, Protein Sci., 20, 482, 10.1002/pro.580 · DOI
Lee J. H., 2007, J. Biol. Chem., 282, 10414, 10.1074/jbc.M610857200 · DOI
Hirschi A., 2010, Nat. Struct. Mol. Biol., 17, 1051, 10.1038/nsmb.1868 · DOI
Chang C. C., 2011, Mol. Cell, 42, 62, 10.1016/j.molcel.2011.02.022 · DOI
Sun Q., 2010, PLoS One, 5, e12819, 10.1371/journal.pone.0012819 · DOI
Harreman M. T., 2004, J. Biol. Chem., 279, 20613, 10.1074/jbc.M401720200 · DOI
Honnappa S., 2005, EMBO J., 24, 261, 10.1038/sj.emboj.7600529 · DOI
Lee C. W., 2010, Proc. Natl. Acad. Sci. U.S.A., 107, 19290, 10.1073/pnas.1013078107 · DOI
Lacy E. R., 2004, Nat. Struct. Mol. Biol., 11, 358, 10.1038/nsmb746 · DOI
Philo J. S., 1996, Biochemistry, 35, 1681, 10.1021/bi9524272 · DOI
Vicentini A. M., 1990, Biochemistry, 29, 8827, 10.1021/bi00489a046 · DOI
Dyson H. J., 2011, Q. Rev. Biophys., 44, 467, 10.1017/S0033583511000060 · DOI
Remaut H., 2006, Trends Biochem. Sci., 31, 436, 10.1016/j.tibs.2006.06.007 · DOI
Fuxreiter M., 2007, Bioinformatics, 23, 950, 10.1093/bioinformatics/btm035 · DOI
Donaldson L. W., 2002, Proc. Natl. Acad. Sci. U.S.A., 99, 14053, 10.1073/pnas.212518799 · DOI
Uversky V. N., 2009, BMC Genomics, 10, S7, 10.1186/1471-2164-10-S1-S7 · DOI
Zhou H. X., 2012, Trends Biochem. Sci., 37, 43, 10.1016/j.tibs.2011.11.002 · DOI
Dunker A. K., 1998, Pac. Symp. Biocomput., 473
Papadakos G., 2012, J. Mol. Biol., 418, 269, 10.1016/j.jmb.2012.01.039 · DOI
Dogan J., 2014, Phys. Chem. Chem. Phys., 16, 6323, 10.1039/C3CP54226B · DOI
Shammas S. L., 2013, J. Phys. Chem. B, 117, 13346, 10.1021/jp404267e · DOI
Freedman S. J., 2002, Proc. Natl. Acad. Sci. U.S.A., 99, 5367, 10.1073/pnas.082117899 · DOI
Freedman S. J., 2003, Nat. Struct. Biol., 10, 504, 10.1038/nsb936 · DOI
Via A., 2007, BMC Bioinformatics, 8, 68, 10.1186/1471-2105-8-68 · DOI
Tan C. S., 2009, Science, 325, 1686, 10.1126/science.1174301 · DOI
Pandit B., 2007, Nat. Genet., 39, 1007, 10.1038/ng2073 · DOI · Paper page
Zhang T., 2001, J. Biol. Chem., 276, 29702, 10.1074/jbc.M011326200 · DOI
Hittinger C. T., 2008, Evol. Dev., 10, 537, 10.1111/j.1525-142X.2008.00269.x · DOI
Beltrao P., 2007, PLoS Comput. Biol., 3, e25, 10.1371/journal.pcbi.0030025 · DOI
Kim J., 2012, PLoS Genet., 8, e1002510, 10.1371/journal.pgen.1002510 · DOI
Zielinska D. F., 2012, Mol. Cell, 46, 542, 10.1016/j.molcel.2012.04.031 · DOI · Paper page
Holt L. J., 2009, Science, 325, 1682, 10.1126/science.1172867 · DOI · Paper page
Nair R., 2003, Nucleic Acids Res., 31, 397, 10.1093/nar/gkg001 · DOI
Boutros R., 2007, Nat. Rev. Cancer, 7, 495, 10.1038/nrc2169 · DOI · Paper page
Primorac I., 2013, J. Cell Biol., 201, 177, 10.1083/jcb.201301130 · DOI
Bruning J. B., 2004, Structure, 12, 2209, 10.1016/j.str.2004.09.018 · DOI · Paper page
Conti E., 2000, Structure, 8, 329, 10.1016/S0969-2126(00)00107-6 · DOI · Paper page
Liu B. A., 2012, Philos. Trans. R. Soc. London, B, Biol. Sci., 367, 2556, 10.1098/rstb.2012.0107 · DOI
Kaneko T., 2012, Cell Commun. Signal, 10, 32, 10.1186/1478-811X-10-32 · DOI
Clery A., 2011, Nat. Struct. Mol. Biol., 18, 443, 10.1038/nsmb.2001 · DOI
Joshi A., 2011, Structure, 19, 1816, 10.1016/j.str.2011.09.020 · DOI
Corsini L., 2007, Nat. Struct. Mol. Biol., 14, 620, 10.1038/nsmb1260 · DOI
Cukier C. D., 2010, Nat. Struct. Mol. Biol., 17, 1058, 10.1038/nsmb.1883 · DOI
Motley A. M., 2000, EMBO Rep., 1, 40, 10.1093/embo-reports/kvd010 · DOI
Finn R. D., 2014, Nucleic Acids Res., 42, D222, 10.1093/nar/gkt1223 · DOI · Paper page
Landgraf C., 2004, PLoS Biol., 2, E14, 10.1371/journal.pbio.0020014 · DOI
Zarrinpar A., 2003, Nature, 426, 676, 10.1038/nature02178 · DOI · Paper page
Ubersax J. A., 2007, Nat. Rev. Mol. Cell Biol., 8, 530, 10.1038/nrm2203 · DOI · Paper page
Liu B. A., 2010, Mol. Cell. Proteomics, 9, 2391, 10.1074/mcp.M110.001586 · DOI
Poy F., 1999, Mol. Cell, 4, 555, 10.1016/S1097-2765(00)80206-3 · DOI
Saksela K., 2012, FEBS Lett., 586, 2609, 10.1016/j.febslet.2012.04.042 · DOI
Bhattacharyya R. P., 2006, Science, 311, 822, 10.1126/science.1120941 · DOI
Ng C., 2008, EMBO J., 27, 804, 10.1038/emboj.2008.18 · DOI
Ottmann C., 2007, EMBO J., 26, 902, 10.1038/sj.emboj.7601530 · DOI
Garron M. L., 2008, J. Mol. Biol., 375, 1320, 10.1016/j.jmb.2007.11.040 · DOI
Nomura M., 2005, J. Mol. Biol., 354, 903, 10.1016/j.jmb.2005.10.008 · DOI
Sahu S. C., 2008, J. Mol. Biol., 375, 1444, 10.1016/j.jmb.2007.11.079 · DOI
Jennings B. H., 2006, Mol. Cell, 22, 645, 10.1016/j.molcel.2006.04.024 · DOI
Hao B., 2007, Mol. Cell, 26, 131, 10.1016/j.molcel.2007.02.022 · DOI
Wu G., 2003, Mol. Cell, 11, 1445, 10.1016/S1097-2765(03)00234-X · DOI · Paper page
Song J. J., 2008, Genes Dev., 22, 1313, 10.1101/gad.1653308 · DOI
Han Z., 2007, Structure, 15, 1306, 10.1016/j.str.2007.08.007 · DOI
Oliver A. W., 2009, EMBO Rep., 10, 990, 10.1038/embor.2009.126 · DOI
Song J. J., 2008, J. Biol. Chem., 283, 35258, 10.1074/jbc.M806900200 · DOI
Stirnimann C. U., 2010, Trends Biochem. Sci., 35, 565, 10.1016/j.tibs.2010.04.003 · DOI · Paper page
Krenn V., 2012, J. Cell Biol., 196, 451, 10.1083/jcb.201110013 · DOI
Gsponer J., 2008, Science, 322, 1365, 10.1126/science.1163581 · DOI · Paper page
Vavouri T., 2009, Cell, 138, 198, 10.1016/j.cell.2009.04.029 · DOI · Paper page
Scott J. D., 2009, Science, 326, 1220, 10.1126/science.1175668 · DOI
Bossi A., 2009, Mol. Syst. Biol., 5, 260, 10.1038/msb.2009.17 · DOI
Rowicka M., 2007, Proc. Natl. Acad. Sci. U.S.A., 104, 16892, 10.1073/pnas.0706022104 · DOI
Jones R. B., 2006, Nature, 439, 168, 10.1038/nature04177 · DOI · Paper page
Cho W., 2006, Sci. STKE, 2006, pe7
Davis M. J., 2012, Mol. Biosyst., 8, 2054, 10.1039/c2mb25050k · DOI
Ellis J. D., 2012, Mol. Cell, 46, 884, 10.1016/j.molcel.2012.05.037 · DOI · Paper page
Weatheritt R. J., 2012, Trends Biochem. Sci., 37, 333, 10.1016/j.tibs.2012.05.001 · DOI
Ferreon J. C., 2009, Proc. Natl. Acad. Sci. U.S.A., 106, 6591, 10.1073/pnas.0811023106 · DOI · Paper page
Akiva E., 2012, PLoS Comput. Biol., 8, e1002341, 10.1371/journal.pcbi.1002341 · DOI
Van Roey K., 2012, Curr. Opin. Struct. Biol., 22, 378, 10.1016/j.sbi.2012.03.004 · DOI
Skaar J. R., 2013, Nat. Rev. Mol. Cell Biol., 14, 369, 10.1038/nrm3582 · DOI
Shin C., 2004, Nat. Rev. Mol. Cell Biol., 5, 727, 10.1038/nrm1467 · DOI · Paper page
Weatheritt R. J., 2012, Nucleic Acids Res., 40, 7123, 10.1093/nar/gks442 · DOI
Jin J., 2012, Philos. Trans. R. Soc. London, B: Biol. Sci., 367, 2540, 10.1098/rstb.2012.0106 · DOI
Diella F., 2008, Front. Biosci., 13, 6580, 10.2741/3175 · DOI · Paper page
Remenyi A., 2006, Curr. Opin. Struct. Biol., 16, 676, 10.1016/j.sbi.2006.10.008 · DOI · Paper page
Skroblin P., 2010, Int. Rev. Cell Mol. Biol., 283, 235, 10.1016/S1937-6448(10)83005-9 · DOI
Roskoski R. J., 2012, Pharmacol. Res., 66, 105, 10.1016/j.phrs.2012.04.005 · DOI · Paper page
Bardwell L., 2006, Biochem. Soc. Trans., 34, 837, 10.1042/BST0340837 · DOI
Ruest P. J., 2001, Mol. Cell. Biol., 21, 7641, 10.1128/MCB.21.22.7641-7652.2001 · DOI
Lobjois V., 2011, Biochem. Biophys. Res. Commun., 410, 87, 10.1016/j.bbrc.2011.05.110 · DOI
Cheng K. Y., 2006, J. Biol. Chem., 281, 23167, 10.1074/jbc.M600480200 · DOI
Lowe E. D., 2002, Biochemistry, 41, 15625, 10.1021/bi0268910 · DOI
Hsiao S. J., 2008, Biochimie, 90, 83, 10.1016/j.biochi.2007.07.012 · DOI
Guettler S., 2011, Cell, 147, 1340, 10.1016/j.cell.2011.10.046 · DOI
Sbodio J. I., 2002, J. Biol. Chem., 277, 31887, 10.1074/jbc.M203916200 · DOI
Zhang Y., 2011, Nat. Cell Biol., 13, 623, 10.1038/ncb2222 · DOI · Paper page
Roy J., 2009, Sci. Signal, 2, re9
Hendrickx A., 2009, Chem. Biol., 16, 365, 10.1016/j.chembiol.2009.02.012 · DOI
Virshup D. M., 2009, Mol. Cell, 33, 537, 10.1016/j.molcel.2009.02.015 · DOI
Bollen M., 2010, Trends Biochem. Sci., 35, 450, 10.1016/j.tibs.2010.03.002 · DOI
Heroes E., 2013, FEBS J., 280, 584, 10.1111/j.1742-4658.2012.08547.x · DOI · Paper page
Vucic D., 2011, Nat. Rev. Mol. Cell Biol., 12, 439, 10.1038/nrm3143 · DOI · Paper page
Nakayama K. I., 2005, Semin. Cell Dev. Biol., 16, 323, 10.1016/j.semcdb.2005.02.010 · DOI · Paper page
Gregory M. A., 2003, J. Biol. Chem., 278, 51606, 10.1074/jbc.M310722200 · DOI · Paper page
Winston J. T., 1999, Genes Dev., 13, 270, 10.1101/gad.13.3.270 · DOI · Paper page
Zur A., 2001, EMBO J., 20, 792, 10.1093/emboj/20.4.792 · DOI
Clute P., 1999, Nat. Cell Biol., 1, 82, 10.1038/10049 · DOI
den Elzen N., 2001, J. Cell Biol., 153, 121, 10.1083/jcb.153.1.121 · DOI · Paper page
Nguyen H. G., 2005, Mol. Cell. Biol., 25, 4977, 10.1128/MCB.25.12.4977-4992.2005 · DOI
Lindon C., 2004, J. Cell Biol., 164, 233, 10.1083/jcb.200309035 · DOI · Paper page
Tasaki T., 2012, Annu. Rev. Biochem., 81, 261, 10.1146/annurev-biochem-051710-093308 · DOI · Paper page
Matta-Camacho E., 2010, Nat. Struct. Mol. Biol., 17, 1182, 10.1038/nsmb.1894 · DOI
Choi W. S., 2010, Nat. Struct. Mol. Biol., 17, 1175, 10.1038/nsmb.1907 · DOI
Sriram S. M., 2011, Nat. Rev. Mol. Cell Biol., 12, 735, 10.1038/nrm3217 · DOI
Matera A. G., 2009, Dev. Cell, 17, 639, 10.1016/j.devcel.2009.10.017 · DOI
Diekmann Y., 2013, Biochem. J., 449, 319, 10.1042/BJ20120957 · DOI
Hung M. C., 2011, J. Cell Sci., 124, 3381, 10.1242/jcs.089110 · DOI · Paper page
Uhlen M., 2010, Nat. Biotechnol., 28, 1248, 10.1038/nbt1210-1248 · DOI · Paper page
Derby M. C., 2007, Int. Rev. Cytol., 261, 47, 10.1016/S0074-7696(07)61002-X · DOI
Pandey K. N., 2010, Curr. Opin. Biotechnol., 21, 611, 10.1016/j.copbio.2010.08.007 · DOI
Kelly B. T., 2008, Nature, 456, 976, 10.1038/nature07422 · DOI
Owen D. J., 1998, Science, 282, 1327, 10.1126/science.282.5392.1327 · DOI · Paper page
Heilker R., 1999, Bioessays, 21, 558, 10.1002/(SICI)1521-1878(199907)21:7<558::AID-BIES4>3.0.CO;2-R · DOI
Eugster A., 2004, Mol. Biol. Cell, 15, 1011, 10.1091/mbc.e03-10-0724 · DOI
Majoul I., 2001, Dev. Cell, 1, 139, 10.1016/S1534-5807(01)00004-1 · DOI
Munro S., 1987, Cell, 48, 899, 10.1016/0092-8674(87)90086-9 · DOI · Paper page
Sorokin A. V., 2007, Biochemistry (Mosc.), 72, 1439, 10.1134/S0006297907130032 · DOI
Malik H. S., 1997, Proc. Natl. Acad. Sci. U.S.A., 94, 13738, 10.1073/pnas.94.25.13738 · DOI
Fu S. C., 2013, Nucleic Acids Res., 41, D338, 10.1093/nar/gks936 · DOI
Dingwall C., 1988, J. Cell Biol., 107, 841, 10.1083/jcb.107.3.841 · DOI
Liang S. H., 1999, J. Biol. Chem., 274, 32699, 10.1074/jbc.274.46.32699 · DOI
Chen C. F., 1996, J. Biol. Chem., 271, 32863, 10.1074/jbc.271.51.32863 · DOI
Stommel J. M., 1999, EMBO J., 18, 1660, 10.1093/emboj/18.6.1660 · DOI · Paper page
van Hengel J., 1999, Proc. Natl. Acad. Sci. U.S.A., 96, 7980, 10.1073/pnas.96.14.7980 · DOI
Hurley J. H., 2000, Annu. Rev. Biophys. Biomol. Struct., 29, 49, 10.1146/annurev.biophys.29.1.49 · DOI · Paper page
Greaves J., 2007, J. Cell Biol., 176, 249, 10.1083/jcb.200610151 · DOI
Akhmanova A., 2005, Curr. Opin. Cell Biol., 17, 47, 10.1016/j.ceb.2004.11.001 · DOI
Jiang K., 2012, Curr. Biol., 22, 1800, 10.1016/j.cub.2012.07.047 · DOI · Paper page
Honnappa S., 2009, Cell, 138, 366, 10.1016/j.cell.2009.04.065 · DOI · Paper page
Mayer B. J., 1991, Proc. Natl. Acad. Sci. U.S.A., 88, 627, 10.1073/pnas.88.2.627 · DOI
Ren R., 1993, Science, 259, 1157, 10.1126/science.8438166 · DOI · Paper page
Pawson T., 1993, Curr. Biol., 3, 434, 10.1016/0960-9822(93)90350-W · DOI · Paper page
Hekman M., 2004, J. Biol. Chem., 279, 14074, 10.1074/jbc.M309620200 · DOI
Buey R. M., 2012, J. Biol. Chem., 287, 28227, 10.1074/jbc.M112.373928 · DOI
Tatham M. H., 2008, Nat. Cell Biol., 10, 538, 10.1038/ncb1716 · DOI · Paper page
Ye H., 2002, Nature, 418, 443, 10.1038/nature00888 · DOI
Giacinti C., 2006, Oncogene, 25, 5220, 10.1038/sj.onc.1209615 · DOI
Dick F. A., 2013, Nat. Rev. Mol. Cell Biol., 14, 297, 10.1038/nrm3567 · DOI · Paper page
Fattaey A. R., 1993, Oncogene, 8, 3149
Soni R., 1995, Plant Cell, 7, 85
Lee J. O., 1998, Nature, 391, 859, 10.1038/36038 · DOI
Nagy L., 2004, Trends Biochem. Sci., 29, 317, 10.1016/j.tibs.2004.04.006 · DOI · Paper page
Privalsky M. L., 2004, Annu. Rev. Physiol., 66, 315, 10.1146/annurev.physiol.66.032802.155556 · DOI · Paper page
Watson P. J., 2012, Mol. Cell. Endocrinol., 348, 440, 10.1016/j.mce.2011.08.033 · DOI
Pawson T., 2007, Oncogene, 26, 1268, 10.1038/sj.onc.1210255 · DOI
Good M. C., 2011, Science, 332, 680, 10.1126/science.1198701 · DOI · Paper page
Findlay G. M., 2013, Cell, 152, 1008, 10.1016/j.cell.2013.01.056 · DOI

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Authors: Van Roey, K., Uyar, B., Weatheritt, R. J., Dinkel, H., Seiler, M., Budd, A., Gibson, T. J., & Davey, N. E.
Venue: Chemical Reviews
Publisher: American Chemical Society (ACS)
Published: 2014-06-13
Volume: 114
Issue: 13
Pages: 6733-6778
ISSN: 0009-2665 (ISSN-L)
1520-6890
DOI: 10.1021/cr400585q
OpenAlex: W2330547698
Cited by: 502
References: 38
FWCI: 2.24
Type: journal article
Language: en
Open access: closed

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Short Linear Motifs: Ubiquitous and Functionally Diverse Protein Interaction Modules Directing Cell Regulation

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