The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Effects of D-cycloserine on extinction of conditioned freezing.
Abstract
The present study tested the prediction that D-cycloserine (DCS), a partial N-methyl-D-aspartate agonist, would facilitate extinction of conditioned freezing in male Sprague-Dawley rats. Rats received 5 light-shock pairings (conditioning). The following day, rats received 6 light-alone presentations (extinction training). Twenty-four hours later, rats received 1 light-alone presentation (test). Subcutaneous DCS injection before or after extinction training significantly enhanced extinction, and the dose-response curve for this effect was linear. Increasing the delay of DCS administration after extinction training led to a linear decrease in the facilitatory effect. The effect of systemic administration was replicated by intra-basolateral amygdala infusion. These results suggest that DCS facilitates extinction of conditioned freezing by acting on consolidation processes partly mediated by the basolateral amygdala.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“administration of the NMDAR partial agonist D-cycloserine (DCS) enhances the acquisition of the extinction memory”
From Retrieval-Dependent Mechanisms Affecting Emotional Memory Persistence: Reconsolidation, Extinction, and the Space in Between (2020) · cites this paper as Ledgerwood et al., 2003
In the citing paper
“with no effect when administered after re-exposure in rodents (Ledgerwood et al., 2003; Lee et al., 2006a)”
From Retrieval-Dependent Mechanisms Affecting Emotional Memory Persistence: Reconsolidation, Extinction, and the Space in Between (2020) · cites this paper as Ledgerwood et al., 2003
In the citing paper
“Preclinical research has demonstrated that DCS facilitates extinction learning and memory in rodent models (Davis et al, 2006; Ledgerwood et al, 2003; Walker et al, 2002).”
From D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial (2014) · cites this paper as Ledgerwood et al, 2003
In the citing paper
“We chose weekly dosing, administered 90 min before exposure sessions, as this regimen has been effective in multiple animal and human fear extinction studies (Ledgerwood et al, 2003; Ressler et al, 2004; Walker et al, 2002)”
From D-cycloserine augmentation of exposure therapy for post-traumatic stress disorder: a pilot randomized clinical trial (2014) · cites this paper as Ledgerwood et al, 2003
In the citing paper
“administration of D-cycloserine (DCS), a partial agonist of the NMDA receptor involved in long-term potentiation (a cellular model of learning), facilitates extinction (e.g., Walker, Ressler, Lu, & Davis, 2002; Ledgerwood, Richardson, & Cranney, 2003).”
From D-cycloserine facilitates context-specific fear extinction learning (2008) · cites this paper as Ledgerwood, Richardson, & Cranney, 2003
In the citing paper
“Our results are generally in agreement with the results of Walker et al (2002) and Ledgerwood et al (2003), in which DCS systemic administration enhanced the extinction of conditioned fear.”
From Effects of Single Prolonged Stress and D-Cycloserine on Contextual Fear Extinction and Hippocampal NMDA Receptor Expression in a Rat Model of PTSD (2008) · cites this paper as Ledgerwood et al (2003)
In the citing paper
“Likewise, though the molecular mechanism of contextual fear extinction remains to be precisely determined, the N-methyl-D-aspartate (NMDA) receptor appears to play a critical role in fear extinction (Falls et al, 1992;Ledgerwood et al, 2003Ledgerwood et al, , 2004Ledgerwood et al, , 2005;;Rodrigues et al, 2001;Santini et al, 2001;Walker et al, 2002).”
From Effects of Single Prolonged Stress and D-Cycloserine on Contextual Fear Extinction and Hippocampal NMDA Receptor Expression in a Rat Model of PTSD (2008) · cites this paper as Ledgerwood et al, 2003
In the citing paper
“The DCS dose (15 mg/kg per rat) was chosen on the basis of the results of other behavioral studies (Ledgerwood et al, 2003(Ledgerwood et al, , 2005;;Walker et al, 2002).”
From Effects of Single Prolonged Stress and D-Cycloserine on Contextual Fear Extinction and Hippocampal NMDA Receptor Expression in a Rat Model of PTSD (2008) · cites this paper as Ledgerwood et al, 2003
Citations
Cites
The Rat Brain in Stereotaxic Coordinates
Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585
LeDoux, J. E. (2000) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.23.1.155 · Cited by 8,444
Neurobiology of Pavlovian fear conditioning
Maren, S. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.897 · Cited by 1,543
Distribution of N-methyl-D-aspartate-sensitive L-[3H]glutamate-binding sites in rat brain
Monaghan, D., & Cotman, C. W. (1985) · Journal of Neuroscience · doi:10.1523/jneurosci.05-11-02909.1985 · Cited by 1,279
NMDA receptors - their role in long-term potentiation
Collingridge, G. L., & Bliss, T. (1987) · Trends in Neurosciences · doi:10.1016/0166-2236(87)90175-5 · Cited by 1,178
Aguado Aguilar, L. (2001) · PubMed · Cited by 1,072
Neural organization of the defensive behavior system responsible for fear
Fanselow, M. S. (1994) · Psychonomic Bulletin & Review · doi:10.3758/bf03210947 · Cited by 1,000
From normal fear to pathological anxiety.
Rosen, J. B., & Schulkin, J. A. (1998) · Psychological Review · doi:10.1037/0033-295x.105.2.325 · Cited by 914
A perceptual-defensive-recuperative model of fear and pain
Bolles, R. C., & Fanselow, M. S. (1980) · Behavioral and Brain Sciences · doi:10.1017/s0140525x0000491x · Cited by 840
Miserendino, M. J. D., Sananes, C. B., Melia, K. R., & Davis, M. (1990) · Nature · doi:10.1038/345716a0 · Cited by 824
Flagged first, then by citations
Research works printed but not linked: 1
- Bouton, 1991, A contextual analysis of fear extinction., 435
Cited by
Sorted by citations
Items 101–200 of 388
D-cycloserine Deters Reacquisition of Cocaine Self-Administration by Augmenting Extinction Learning
Dhonnchadha, B. Á. N., Szalay, J. J., Achat‐Mendes, C., Platt, D. M., Otto, M. W., Spealman, R. D., & Kantak, K. M. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.139 · Cited by 93
Augmentation of Extinction and Inhibitory Learning in Anxiety and Trauma-Related Disorders
Lebois, L. A. M., Seligowski, A. V., Wolff, J. D., Hill, S. B., & Ressler, K. J. (2019) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-050718-095634 · Cited by 97
Yang, Y.-L., & Lu, K. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.04.003 · Cited by 93
Ori, R., Amos, T., Bergman, H., Soares‐Weiser, K., Ipser, J., & Stein, D. J. (2015) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007803.pub2 · Cited by 104
Big Effects of Small RNAs: A Review of MicroRNAs in Anxiety
Malan‐Müller, S., Hemmings, S. M. J., & Seedat, S. (2012) · Molecular Neurobiology · doi:10.1007/s12035-012-8374-6 · Cited by 91
Opioid Receptors Regulate the Extinction of Pavlovian Fear Conditioning.
McNally, G. P., & Westbrook, R. F. (2003) · Behavioral Neuroscience · doi:10.1037/0735-7044.117.6.1292 · Cited by 91
Human fear conditioning: From neuroscience to the clinic
Fullana, M. A., Dunsmoor, J. E., Schruers, K. R. J., Savage, H. S., Bach, D. R., & Harrison, B. J. (2019) · Behaviour Research and Therapy · doi:10.1016/j.brat.2019.103528 · Cited by 96
Siegmund, A., Golfels, F., Finck, C., Halisch, A., Räth, D., Plag, J., & Ströhle, A. (2011) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2011.01.020 · Cited by 89
Treating disgust in anxiety disorders.
Mason, E. C., & Richardson, R. (2012) · Clinical Psychology Science and Practice · doi:10.1111/j.1468-2850.2012.01282.x · Cited by 95
Self-citationAna, E. J. S., Rounsaville, B. J., Frankforter, T. L., Nich, C., Babuscio, T. A., Poling, J. C., Gonsai, K., Hill, K. P., & Carroll, K. M. (2009) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2009.04.023 · Cited by 88
Harvey, B. H., & Shahid, M. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.06.014 · Cited by 90
Haaker, J., Maren, S., Andreatta, M., Merz, C. J., Richter, J., Richter, S. H., Drexler, S. M., Lange, M. D., Jüngling, K., Nees, F., et al. (2019) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2019.09.020 · Cited by 92
Nasir, M., Trujillo, D., Levine, J. L. S., Dwyer, J. B., Rupp, Z. W., & Bloch, M. H. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.548505 · Cited by 94
Bustos, S. G., Giachero, M., Maldonado, H., & Molina, V. A. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.215 · Cited by 91
Fear Processing, Psychophysiology, and PTSD
Norrholm, S. D., & Jovanović, T. (2018) · Harvard Review of Psychiatry · doi:10.1097/hrp.0000000000000189 · Cited by 92
Effects of D-cycloserine on extinction of learned fear to an olfactory cue
Weber, M., Hart, J., & Richardson, R. (2007) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2006.12.010 · Cited by 83
Self-citationWhittle, N., Hauschild, M., Lübec, G., Holmes, A., & Singewald, N. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0849-10.2010 · Cited by 83
Wang, W., Kang, S., Liu, W., Li, M., Liu, Y., Yu, C. F., Chen, J., Chi, Z., He, L., & Liu, J. (2012) · Journal of Neuroscience · doi:10.1523/jneurosci.1991-12.2012 · Cited by 81
Novel Approach to the Role of NMDA Receptors in Traumatic Brain Injury
Shohami, E., & Biegon, A. R. (2014) · CNS & Neurological Disorders - Drug Targets · doi:10.2174/18715273113126660196 · Cited by 80
Chhatwal, J. P., Gutman, A. R., Maguschak, K. A., Bowser, M. E., Yang, Y., Davis, M., & Ressler, K. J. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.97 · Cited by 80
Stress and Amygdala Suppression of Metaplasticity in the Medial Prefrontal Cortex
Richter‐Levin, G., & Maroun, M. (2010) · Cerebral Cortex · doi:10.1093/cercor/bhp311 · Cited by 79
Mechanisms of fear learning and extinction: synaptic plasticity–fear memory connection
Luchkina, N. V., & Bolshakov, V. Y. (2018) · Psychopharmacology · doi:10.1007/s00213-018-5104-4 · Cited by 87
Learning and memory in conditioned fear extinction: Effects of d-cycloserine
Vervliet, B. (2007) · Acta Psychologica · doi:10.1016/j.actpsy.2007.07.001 · Cited by 78
Krystal, J. H., Tolin, D. F., Sanacora, G., Castner, S. A., Williams, G. V., Aikins, D. E., Hoffman, R. E., & D'Souza, D. C. (2009) · Drug Discovery Today · doi:10.1016/j.drudis.2009.05.002 · Cited by 76
d-Cycloserine Augmentation of Cognitive Behavioral Therapy for Anxiety Disorders: an Update
Hofmann, S. G., Otto, M. W., Pollack, M. H., & Smits, J. A. J. (2014) · Current Psychiatry Reports · doi:10.1007/s11920-014-0532-2 · Cited by 76
Whittle, N., Schmuckermair, C., Gunduz‐Cinar, O., Hauschild, M., Ferraguti, F., Holmes, A., & Singewald, N. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.06.001 · Cited by 76
Augmentation of exposure therapy with post-session administration of D-cycloserine
Tart, C. D., Handelsman, P. R., DeBoer, L. B., Rosenfield, D., Pollack, M. H., Hofmann, S. G., Powers, M. B., Otto, M. W., & Smits, J. A. J. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.09.024 · Cited by 75
Yang, Y.-L., Chao, P.-K., Ro, L., Wo, Y., & Lu, K.-T. (2007) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301215 · Cited by 79
D-Cycloserine Effects on Extinction of Conditioned Responses to Drug-Related Cues
Myers, K. M., & Carlezon, W. A. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.02.030 · Cited by 72
Kilaru, V., Iyer, S. V., Almli, L. M., Stevens, J. S., Lori, A., Jovanović, T., Ely, T. D., Bradley, B., Binder, E. B., Koen, N., et al. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.69 · Cited by 71
Hillman, B. G., Gupta, S. C., Stairs, D. J., Buonanno, A., & Dravid, S. M. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.01.008 · Cited by 73
Yamada, D., Zushida, K., Wada, K., & Sekiguchi, M. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.86 · Cited by 72
Woods, A. M., & Bouton, M. E. (2008) · Learning & Memory · doi:10.1101/lm.1078508 · Cited by 70
Enhancement of psychosocial treatment with D-cycloserine: Models, moderators, and future directions
Otto, M. W., Kredlow, M. A., Smits, J. A. J., Hofmann, S. G., Tolin, D. F., de Kleine, R. A., van Minnen, A., Evins, A. E., & Pollack, M. H. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.09.007 · Cited by 70
D-cycloserine potentiates the reconsolidation of cocaine-associated memories
Lee, J. L. C., Gardner, R. J., Butler, V. J., & Everitt, B. J. (2009) · Learning & Memory · doi:10.1101/lm.1186609 · Cited by 70
Influence of ethanol withdrawal on fear memory: Effect of d-cycloserine
Bertotto, M. E., Bustos, S. G., Molina, V. A., & Martijena, I. D. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.07.013 · Cited by 70
Evidence-Based Treatment of Post-Traumatic Stress Disorder
Difede, J., Olden, M., & Cukor, J. (2014) · Annual Review of Medicine · doi:10.1146/annurev-med-051812-145438 · Cited by 70
Raut, S. B., Marathe, P. A., van Eijk, L., Eri, R. D., Ravindran, M., Benedek, D. M., Ursano, R. J., Canales, J. J., & Johnson, L. R. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108195 · Cited by 74
Dadds, M. R., & Rhodes, T. (2008) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2008.0029 · Cited by 69
From Extinction Learning to Anxiety Treatment: Mind the Gap
Carpenter, J. K., Pinaire, M., & Hofmann, S. G. (2019) · Brain Sciences · doi:10.3390/brainsci9070164 · Cited by 77
Bukalo, O., Pinard, C. R., & Holmes, A. (2014) · British Journal of Pharmacology · doi:10.1111/bph.12779 · Cited by 73
Pharmacological enhancement of exposure-based treatment in PTSD: a qualitative review
de Kleine, R. A., ROTHBAUM, B. O., & van Minnen, A. (2013) · European Journal of Psychotraumatology · doi:10.3402/ejpt.v4i0.21626 · Cited by 72
Augmentation of Cognitive Behavioral Therapy with Pharmacotherapy
Ganasen, K. A., Ipser, J., & Stein, D. J. (2010) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2010.04.008 · Cited by 68
A window of vulnerability: Impaired fear extinction in adolescence
Baker, K., Den, M. L., Graham, B. M., & Richardson, R. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.10.009 · Cited by 73
Self-citationFear Extinction as a Model for Synaptic Plasticity in Major Depressive Disorder
Kühn, M., Höger, N., Feige, B., Blechert, J., Normann, C., & Nissen, C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0115280 · Cited by 65
Curlik, D. M., & Shors, T. J. (2010) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2010.21597 · Cited by 65
Langton, J. M., & Richardson, R. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.32 · Cited by 63
Self-citationCain, C. K., Godsil, B. P., Jami, S. A., & Barad, M. (2005) · Learning & Memory · doi:10.1101/lm.88805 · Cited by 62
Myers, K. M., & Carlezon, W. A. (2009) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.08.015 · Cited by 61
d-Cycloserine as an augmentation strategy for cognitive behavioral therapy of anxiety disorders
Hofmann, S. G., Wu, J. Q., & Boettcher, H. (2013) · Biology of Mood & Anxiety Disorders · doi:10.1186/2045-5380-3-11 · Cited by 59
Effects of pharmacological manipulations of NMDA-receptors on deliberation in the Multiple-T task
Blumenthal, A., Steiner, A. P., Seeland, K. D., & Redish, A. D. (2011) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2011.01.011 · Cited by 61
Cognitive remediation in the treatment of stimulant abuse disorders: A research agenda.
Vocci, F. J. (2008) · Experimental and Clinical Psychopharmacology · doi:10.1037/a0014101 · Cited by 62
Cognitive enhancers for facilitating drug cue extinction: Insights from animal models
Dhonnchadha, B. Á. N., & Kantak, K. M. (2011) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2011.01.018 · Cited by 57
Siette, J., Reichelt, A. C., & Westbrook, R. F. (2014) · Learning & Memory · doi:10.1101/lm.032557.113 · Cited by 65
STEINGLASS, J., SYSKO, R., SCHEBENDACH, J., BROFT, A., STROBER, M., & WALSH, B. T. (2007) · Journal of Psychiatric Practice · doi:10.1097/01.pra.0000281484.89075.a8 · Cited by 56
Pharmacological enhancement of fear reduction: preclinical models
Graham, B. M., Langton, J. M., & Richardson, R. (2010) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2010.01175.x · Cited by 57
Self-citationCombining pharmacotherapy with cognitive behavioral therapy: Traditional and new approaches
Davis, M., Barad, M., Otto, M. W., & Southwick, S. (2006) · Journal of Traumatic Stress · doi:10.1002/jts.20149 · Cited by 55
Impaired fear extinction in adolescent rodents: Behavioural and neural analyses
Baker, K., Bisby, M. A., & Richardson, R. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.05.019 · Cited by 60
Self-citationKuriyama, K., Honma, M., Soshi, T., Fujii, T., & Kim, Y. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2353-x · Cited by 54
Ogden, K. K., Khatri, A., Traynelis, S. F., & Heldt, S. A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.241 · Cited by 54
Otto, M. W., Basden, S. L., Leyro, T. M., McHugh, R. K., & Hofmann, S. G. (2007) · CNS Spectrums · doi:10.1017/s1092852900020526 · Cited by 53
Augmentation of Fear Extinction by D-Cycloserine is Blocked by Proteasome Inhibitors
Mao, S.-C., Lin, H., & Gean, P. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.30 · Cited by 51
A Meta-Analysis of d-Cycloserine in Exposure-Based Treatment
Mcguire, J. F., Wu, M. S., Piacentini, J. C., McCracken, J. T., & Storch, E. A. (2016) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15r10334 · Cited by 52
Akirav, I., Segev, A., Motanis, H., & Maroun, M. (2009) · Learning & Memory · doi:10.1101/lm.1565109 · Cited by 51
Boccia, M. M., Blake, M. G., Baratti, C. M., & McGaugh, J. L. (2008) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2008.07.012 · Cited by 50
Effects of REM deprivation and an NMDA agonist on the extinction of conditioned fear
Silvestri, A. J., & Root, D. H. (2007) · Physiology & Behavior · doi:10.1016/j.physbeh.2007.08.020 · Cited by 53
The effects of yohimbine and amphetamine on fear expression and extinction in rats
Mueller, D. T., Olivera-Figueroa, L. A., Pine, D. S., & Quirk, G. J. (2009) · Psychopharmacology · doi:10.1007/s00213-009-1491-x · Cited by 49
Sakurai, S., Yu, L., & Tan, S.-E. (2007) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3282ee7b62 · Cited by 48
Callaghan, B. L., Graham, B. M., Li, S., & Richardson, R. (2013) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2013.00090 · Cited by 50
Self-citationTian, S., Gao, J., Han, L., Fu, J., Li, C., & Li, Z. (2008) · Neuroscience · doi:10.1016/j.neuroscience.2008.03.005 · Cited by 48
Pharmacological Enhancement of Behavioral Therapy: Focus on Posttraumatic Stress Disorder
Choi, D. C., ROTHBAUM, B. O., Gerardi, M. A., & Ressler, K. J. (2009) · Current topics in behavioral neurosciences · doi:10.1007/7854_2009_10 · Cited by 47
Park, J. M., Small, B. J., GELLER, D. A., Murphy, T. K., Lewin, A. B., & Storch, E. A. (2013) · Journal of Child and Family Studies · doi:10.1007/s10826-013-9742-1 · Cited by 49
Extinction: Behavioral Mechanisms and Their Implications
Bouton, M. E., & Woods, A. M. (2008) · Elsevier eBooks · doi:10.1016/b978-012370509-9.00088-7 · Cited by 46
Inslicht, S. S., Niles, A. N., Metzler, T. J., Lipshitz, S. L., Otte, C., Milad, M. R., Orr, S. P., Marmar, C. R., & Neylan, T. C. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-021-01222-z · Cited by 44
Ren, J., Li, X., Zhang, X., Li, M., Wang, Y., & Ma, Y. (2013) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2013.02.017 · Cited by 44
Psychosocial Approaches of Acute Stress Reactions
Bryant, R. A. (2005) · CNS Spectrums · doi:10.1017/s1092852900019453 · Cited by 45
Acheson, D. T., Feifel, D., Kamenski, M., Mckinney, R., & Risbrough, V. B. (2015) · Depression and Anxiety · doi:10.1002/da.22362 · Cited by 44
Kamboj, S. K., Joye, A., Das, R. K., Gibson, A. J. W., Morgan, C. J. A., & Curran, H. V. (2012) · Psychopharmacology · doi:10.1007/s00213-011-2571-2 · Cited by 44
Fibroblast Growth Factor-2 Enhances Extinction and Reduces Renewal of Conditioned Fear
Graham, B. M., & Richardson, R. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2010.3 · Cited by 44
Self-citationAdvances in pharmacotherapy for pediatric anxiety disorders
Rynn, M. A., Puliafico, A. C., Heleniak, C. M., Rikhi, P., Ghalib, K., & Vidair, H. B. (2011) · Depression and Anxiety · doi:10.1002/da.20769 · Cited by 45
Effects of D-Cycloserine on Extinction: Consequences of Prior Exposure to Imipramine
Werner-Seidler, A., & Richardson, R. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.04.010 · Cited by 43
Self-citationGraham, B. M., Callaghan, B. L., & Richardson, R. (2014) · Behaviour Research and Therapy · doi:10.1016/j.brat.2014.07.012 · Cited by 49
Self-citationEffects of MK-801 on recognition and neurodegeneration in an MPTP-induced Parkinson's rat model
Hsieh, M., Gu, S.-L., Ho, S.-C., Pawlak, C. R., Lin, C., Ho, Y., Lai, T., & Wu, F.-Y. (2012) · Behavioural Brain Research · doi:10.1016/j.bbr.2011.12.035 · Cited by 42
Pei, J.-C., Luo, D.-Z., Gau, S.-S., Chang, C., & Lai, W. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.742058 · Cited by 48
Akirav, I. (2006) · Neuropsychopharmacology · doi:10.1038/sj.npp.1301050 · Cited by 41
The role of GABA and anxiety in the reconsolidation of conditioned fear.
Zhang, S., & Cranney, J. (2008) · Behavioral Neuroscience · doi:10.1037/a0013273 · Cited by 44
Self-citationPeskin, M., Wyka, K., Cukor, J., Olden, M., Altemus, M., Lee, F. S., & Difede, J. (2019) · Journal of Anxiety Disorders · doi:10.1016/j.janxdis.2018.03.001 · Cited by 40
Graham, B. M., & Richardson, R. (2009) · Neuropsychopharmacology · doi:10.1038/npp.2009.14 · Cited by 40
Self-citationTranslational research perspectives on maximizing the effectiveness of exposure therapy
Powers, M. B., Smits, J. A. J., Leyro, T. M., & Otto, M. W. (2007) · Elsevier eBooks · doi:10.1016/b978-012587421-2/50005-3 · Cited by 40
Kamboj, S. K., Massey-Chase, R. A., Rodney, L., Das, R., Almahdi, B., Curran, H. V., & Morgan, C. J. A. (2011) · Psychopharmacology · doi:10.1007/s00213-011-2254-z · Cited by 39
Kelamangalath, L., Swant, J., Stramiello, M., & Wagner, J. J. (2007) · Behavioural Brain Research · doi:10.1016/j.bbr.2007.08.001 · Cited by 38
The Role of the Medial Prefrontal Cortex in Regulating Social Familiarity-Induced Anxiolysis
Lungwitz, E. A., Stuber, G. D., Johnson, P. L., Dietrich, A. D., Schartz, N. D., Hanrahan, B., Shekhar, A., & Truitt, W. A. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.302 · Cited by 39
Toth, I., Dietz, M., Peterlik, D., Huber, S. E., Fendt, M., Neumann, I. D., Flor, P. J., & Slattery, D. A. (2011) · Neuropharmacology · doi:10.1016/j.neuropharm.2011.10.021 · Cited by 39
Role of the basolateral amygdala and NMDA receptors in higher-order conditioned fear
Parkes, S. L., & Westbrook, R. F. (2011) · Reviews in the Neurosciences · doi:10.1515/rns.2011.025 · Cited by 40
Associative Learning and Conditioning Theory
Laborda, M. A., McConnell, B. L., & Miller, R. R. (2011) · Cited by 36
Memory of fearful events: the role of fibroblast growth factor-2 in fear acquisition and extinction
Graham, B. M., & Richardson, R. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.05.041 · Cited by 39
Self-citationd-Cycloserine and performance under different states of anxiety in healthy volunteers
Bailey, J., Papadopoulos, A., Lingford-Hughes, A. R., & Nutt, D. (2007) · Psychopharmacology · doi:10.1007/s00213-007-0817-9 · Cited by 37
Fragale, J. E. C., Khariv, V., Gregor, D. M., Smith, I. M., Jiao, X., Elkabes, S., Servatius, R. J., Pang, K. C. H., & Beck, K. D. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.11.002 · Cited by 39
Sharp, W. G., Allen, A. G., Stubbs, K. H., Criado, K. K., Sanders, R., McCracken, C. E., Parsons, R. G., Scahill, L. D., & Gourley, S. L. (2017) · Translational Psychiatry · doi:10.1038/tp.2017.126 · Cited by 39
Effects of D-Cycloserine Administration on Weekly Nonemotional Memory Tasks in Healthy Participants
Otto, M. W., Basden, S. L., McHugh, R. K., Kantak, K. M., Deckersbach, T., Cather, C., GOFF, D. C., Hofmann, S. G., Berry, A. C., & Smits, J. A. J. (2008) · Psychotherapy and Psychosomatics · doi:10.1159/000172620 · Cited by 37
Metadata
- Authors
- Ledgerwood, L., Richardson, R., & Cranney, J.
- Affiliations
- UNSW Sydney (AU)
- Venue
- Behavioral Neuroscience
- Published
- 2003
- Volume
- 117
- Issue
- 2
- Pages
- 341-349
- ISSN
- 0735-7044 (ISSN-L)
- 1939-0084
- OpenAlex
- W2129939370
- Cited by
- 388
- References
- 46
- Citations by year
- 2026: 3 · 2025: 6 · 2024: 4 · 2023: 3 · 2022: 9 · 2021: 11 · 2020: 9 · 2019: 12 · 2018: 16 · 2017: 19 · 2016: 10 · 2015: 16 · 2014: 18 · 2013: 28 · 2012: 25
- FWCI
- 8.07
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Behavioral Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- D-cycloserine, extinction, conditioned freezing, NMDA receptor agonist, basolateral amygdala, memory consolidation, fear extinction, dose-response relationship
- MeSH terms
- Amygdala, Analysis of Variance, Animals, Brain Mapping, Conditioning, Psychological, Cycloserine, Dose-Response Relationship, Drug, Drug Administration Routes, Extinction, Psychological, Male, Reflex, Startle, Time Factors, Rats, Sprague-Dawley, Excitatory Amino Acid Agonists, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
