Assessing and interpreting personality change and continuity in patients treated for major depression.
Abstract
Structural, mean- and individual-level, differential, and ipsative personality continuity were examined in 599 patients treated for major depression assigned to 1 of 6 forms of a 6-month pharmaco-psychotherapy program. Covariation among traits from the Five Factor model remained invariant across treatment, and patients described themselves as slightly more extraverted, open to experience, agreeable and conscientious, and substantially more emotional stable after treatment. Trait changes were only to a small extent explained by changes in depression severity. There was evidence for differential, individual-level, and ipsative stability, with stable personality profiles in terms of shape and to a lesser extent in terms of scatter and elevation. Traits remain relatively stable, except for emotional stability, despite the depressive state and the psychopharmacological interventions.
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Neuroticism is elevated in current and remitted depression.
“First, neuroticism—the propensity to experience negative emotions—is elevated in current and remitted depression (De Fruyt et al, 2006; Klein et al, 2011), and predicts first onset of MDD (Kendler et al, 2006).”
From Neural Correlates of Three Promising Endophenotypes of Depression: Evidence from the EMBARC Study (2016) · cites this paper as De Fruyt et al, 2006
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- Authors
- De Fruyt, F., Van Leeuwen, K., Bagby, R. M., Rolland, J.-P., & Rouillon, F.
- Affiliations
- Ghent University (BE)
- Université Paris Nanterre (FR)
- Hôpital Albert-Chenevier (FR)
- Venue
- Psychological Assessment
- Published
- 2006
- Volume
- 18
- Issue
- 1
- Pages
- 71-80
- ISSN
- 1040-3590 (ISSN-L)
- 1939-134X
- OpenAlex
- W2007449032
- Cited by
- 168
- References
- 45
- Citations by year
- 2025: 4 · 2024: 5 · 2023: 5 · 2022: 10 · 2021: 8 · 2020: 6 · 2019: 12 · 2018: 9 · 2017: 14 · 2016: 13 · 2015: 7 · 2014: 9 · 2013: 11 · 2012: 12
- FWCI
- 11.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Psychological Assessment (publishedVersion)
- PubMed (publishedVersion)
- Ghent University Academic Bibliography (Ghent University) (submittedVersion)
- Lirias (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Personality Traits and Psychology
- Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
- Social Sciences › Psychology › Applied Psychology › Psychological Testing and Assessment
- Keywords
- personality change, personality continuity, major depressive disorder, Big Five personality traits, emotional stability, personality stability, depression severity, psychopharmacological treatment, psychotherapy
- MeSH terms
- Adolescent, Adult, Aged, Antidepressive Agents, Combined Modality Therapy, Major Depressive Disorder, Double-Blind Method, Electroconvulsive Therapy, Female, Follow-Up Studies, Hospitalization, Humans, Male, Middle Aged, Personality Disorders, Personality Inventory, Psychotherapy, Treatment Outcome
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