Acetylcholine receptors containing the β2 subunit are involved in the reinforcing properties of nicotine

Picciotto, Marina R., Zoli, Michele, Rimondini, Roberto, Léna, Clément, Marubio, Lisa M., Pich, Emilio Merlo, Fuxe, Kjell, Changeux, Jean-Pierre·1998·Nature

Cited by (148)

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  7. Reinforcing effects of nicotine microinjections into the ventral tegmental area of mice: dependence on cholinergic nicotinic and dopaminergic D1 receptors
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  10. Nicotine and endogenous opioids: neurochemical and pharmacological evidence
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  11. An extracellular protein microdomain controls up-regulation of neuronal nicotinic acetylcholine receptors by nicotine
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  12. Effects of ginsenoside Rg2 on human neuronal nicotinic acetylcholine receptors
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  13. Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors
    Henderson, Brandon J., Srinivasan, Rahul, Nichols, Weston A., Dilworth, Crystal N., Gutierrez, Diana F., Mackey, Elisha D.W., McKinney, Sheri, Drenan, Ryan M., Richards, Christopher I., Lester, Henry A. · 2014 · Journal of General Physiology
  14. Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome
    Besson, M., David, V., Suarez, S., Cormier, A., Cazala, P., Changeux, J.-P., Granon, S. · 2006 · Psychopharmacology
  15. β2-Subunit-containing nicotinic acetylcholine receptors are involved in nicotine-induced increases in conditioned reinforcement but not progressive ratio responding for food in C57BL/6 mice
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  16. Varenicline Is a Potent Partial Agonist at α6β2* Nicotinic Acetylcholine Receptors in Rat and Monkey Striatum
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  17. Structural determinants of α4β2 nicotinic acetylcholine receptor trafficking
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  18. The α3β4* nicotinic acetylcholine receptor subtype mediates nicotine reward and physical nicotine withdrawal signs independently of the α5 subunit in the mouse
    Jackson, Kia J., Sanjakdar, Sarah S., Muldoon, Pretal P., McIntosh, J. Michael, Damaj, M. Imad · 2013 · Neuropharmacology
  19. Cholinergic modulation of dopamine pathways through nicotinic acetylcholine receptors
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  20. β2 subunit containing acetylcholine receptors mediate nicotine withdrawal deficits in the acquisition of contextual fear conditioning
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  21. Nicotine addiction and psychiatric disorders
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  22. Changes in the Cholinergic System between Bipolar Depression and Euthymia as Measured with [123I]5IA Single Photon Emission Computed Tomography
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  23. From Men to Mice: CHRNA5/CHRNA3, Smoking Behavior and Disease
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  24. Age dependent nicotinic influences over dopamine neuron synaptic plasticity
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  25. Addiction‐related neuroadaptations following chronic nicotine exposure
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  26. Hippocampal nAChRs mediate nicotine withdrawal-related learning deficits
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  27. Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of α4β2 nicotinic receptors in rats
    Spiller, Krista, Xi, Zheng-Xiong, Li, Xia, Ashby, Charles R., Callahan, Patrick M., Tehim, Ashok, Gardner, Eliot L. · 2009 · Neuropharmacology
  28. Involvement of cholinergic neuronal systems in intravenous cocaine self-administration
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  29. Pharmacotherapy for smoking cessation: present and future
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  30. Cell autonomy, receptor autonomy, and thermodynamics in nicotine receptor up-regulation
    Nashmi, Raad, Lester, Henry · 2007 · Biochemical Pharmacology
  31. A concurrent excitation and inhibition of dopaminergic subpopulations in response to nicotine
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  32. Role of α7- and β4-Containing Nicotinic Acetylcholine Receptors in the Affective and Somatic Aspects of Nicotine Withdrawal: Studies in Knockout Mice
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  33. High-affinity nicotinic acetylcholine receptor expression and trafficking abnormalities in psychiatric illness
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  35. Mesolimbic Dopamine and Habenulo-Interpeduncular Pathways in Nicotine Withdrawal
    Dani, J. A., De Biasi, M. · 2013 · Cold Spring Harbor Perspectives in Medicine
  36. Nicotinic receptors modulating somatodendritic and terminal dopamine release differ pharmacologically
    Reuben, Melanie, Boye, Sandra, Clarke, Paul B.S · 2000 · European Journal of Pharmacology
  37. Contribution of dihydro-beta-erythroidine sensitive nicotinic acetylcholine receptors in the ventral tegmental area to cocaine-induced behavioral sensitization in rats
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  38. Nonaggressive and adapted social cognition is controlled by the interplay between noradrenergic and nicotinic receptor mechanisms in the prefrontal cortex
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  39. The Ferrier Lecture 1998. The molecular biology of consciousness investigated with genetically modified mice
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  40. Sex Differences in the Nicotinic Acetylcholine Receptor System of Rodents: Impacts on Nicotine and Alcohol Reward Behaviors
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  41. Evolution in Neuromodulation—The Differential Roles of Acetylcholine in Higher Order Association vs. Primary Visual Cortices
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  42. Route of nicotine administration influences in vivo dopamine neuron activity: habituation, needle injection, and cannula infusion
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  43. Regulation of α4β2α5 nicotinic acetylcholinergic receptors in rat cerebral cortex in early and late adolescence: Sex differences in response to chronic nicotine
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  44. Short- and Long-Lasting Consequences of<i>In Vivo</i>Nicotine Treatment on Hippocampal Excitability
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  45. Alpha4 containing nicotinic receptors are positioned to mediate postsynaptic effects on 5-HT neurons in the rat dorsal raphe nucleus
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  46. Vulnerability to nicotine self-administration in adolescent mice correlates with age-specific expression of α4* nicotinic receptors
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  47. The dendritically targeted protein Dendrin is induced by acute nicotine in cortical regions of adolescent rat brain
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