The transcriptional co-activator p/CIP binds CBP and mediates nuclear-receptor function

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

LAEMMLI, U. K. (1970) · Nature · doi:10.1038/227680a0 · Cited by 249,961

Nuclear protein CBP is a coactivator for the transcription factor CREB

Kwok, R. P. S., Lundblad, J. R., Chrivia, J. C., Richards, J. P., Bächinger, H. P., Brennan, R. G., Roberts, S. G. E., Green, M. R., & Goodman, R. H. (1994) · Nature · doi:10.1038/370223a0 · Cited by 1,443

Activation function 2 (AF-2) of retinoic acid receptor and 9-cis retinoic acid receptor: Presence of a conserved autonomous constitutive activating domain and influence of the nature of the response element on AF-2 activity

Durand, B., Saunders, M., Gaudon, C., Roy, B., Losson, R., & Chambon, P. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06872.x · Cited by 354

Regulation of chromatin by histone modifications

Bannister, A. J., & Kouzarides, T. (2011) · Cell Research · doi:10.1038/cr.2011.22 · Cited by 6,012

A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis

Puigserver, P., Wu, Z., Park, C. W., Graves, R., Wright, M., & Spiegelman, B. M. (1998) · Cell · doi:10.1016/s0092-8674(00)81410-5 · Cited by 3,864

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

Wright, P. E., & Dyson, H. J. (1999) · Journal of Molecular Biology · doi:10.1006/jmbi.1999.3110 · Cited by 2,968

The mechanisms of action of PPARs

Berger, J., & Moller, D. E. (2002) · Annual Review of Medicine · doi:10.1146/annurev.med.53.082901.104018 · Cited by 2,659

The coregulator exchange in transcriptional functions of nuclear receptors

Glass, C. K., & Rosenfeld, M. G. (2000) · Genes & Development · doi:10.1101/gad.14.2.121 · Cited by 2,233

Physiological and Molecular Basis of Thyroid Hormone Action

Yen, P. M. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1097 · Cited by 2,011

Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

McKenna, N. J., & O'Malley, B. W. (2002) · Cell · doi:10.1016/s0092-8674(02)00641-4 · Cited by 1,463

The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes

Vega, R. B., Huss, J. M., & Kelly, D. P. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1868-1876.2000 · Cited by 1,195

Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response

Rosenfeld, M. G., Lunyak, V. V., & Glass, C. K. (2006) · Genes & Development · doi:10.1101/gad.1424806 · Cited by 952

Coregulator Function: A Key to Understanding Tissue Specificity of Selective Receptor Modulators

Smith, C. L., & O’Malley, B. W. (2004) · Endocrine Reviews · doi:10.1210/er.2003-0023 · Cited by 931

Androgen Receptor (AR) Coregulators: An Overview

Heinlein, C. A., & Chang, C. (2002) · Endocrine Reviews · doi:10.1210/edrv.23.2.0460 · Cited by 943

The GRAS gene family in Arabidopsis: sequence characterization and basic expression analysis of the SCARECROW‐LIKE genes

Pysh, L. D., Wysocka‐Diller, J. W., Camilleri, C., Bouchez, D., & Benfey, P. N. (1999) · The Plant Journal · doi:10.1046/j.1365-313x.1999.00431.x · Cited by 698

The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins

McMahon, S. B., Van Buskirk, H. A., Dugan, K. A., Copeland, T. D., & Cole, M. D. (1998) · Cell · doi:10.1016/s0092-8674(00)81479-8 · Cited by 693

Diverse signaling pathways modulate nuclear receptor recruitment of N-CoR and SMRT complexes.

Lavinsky, R. M., Jepsen, K., Heinzel, T., Torchia, J., Mullen, T.-M., Schiff, R., Del-Rio, A. L., Ricote, M., Ngo, S., Gemsch, J., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.6.2920 · Cited by 660

Transcriptional Cross Talk between NF-κB and p53

Webster, G. A., & Perkins, N. D. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.5.3485 · Cited by 598

Glucocorticoid receptor control of transcription: precision and plasticity via allostery

Weikum, E. R., Knuesel, M. T., Ortlund, E. A., & Yamamoto, K. R. (2017) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.152 · Cited by 533

Coregulator codes of transcriptional regulation by nuclear receptors

Rosenfeld, M. G., & Glass, C. K. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100041200 · Cited by 509

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex

Fryer, C. J., & Archer, T. K. (1998) · Nature · doi:10.1038/30032 · Cited by 511

Recruitment of CBP/p300 by the IFNβ Enhanceosome Is Required for Synergistic Activation of Transcription

Merika, M., Williams, A. J., Chen, G., Collins, T., & Thanos, D. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80028-3 · Cited by 435

The Human Tumor Antigen PRAME Is a Dominant Repressor of Retinoic Acid Receptor Signaling

Epping, M. T., Wang, L., Edel, M. J., Carlée, L., Hernandez, M., & Bernards, R. (2005) · Cell · doi:10.1016/j.cell.2005.07.003 · Cited by 432

Nuclear receptor-binding sites of coactivators glucocorticoid receptor interacting protein 1 (GRIP1) and steroid receptor coactivator 1 (SRC-1): multiple motifs with different binding specificities

Ding, X. F., Anderson, C. M., Ma, H., Hong, H., Uht, R. M., Kushner, P. J., & Stallcup, M. R. (1998) · Molecular Endocrinology · doi:10.1210/mend.12.2.0065 · Cited by 434

Retinoic acid receptors: From molecular mechanisms to cancer therapy

di Masi, A., Leboffe, L., De Marinis, E., Pagano, F., Cicconi, L., Rochette-Egly, C., Lo-Coco, F., Ascenzi, P., & Nervi, C. (2015) · Molecular Aspects of Medicine · doi:10.1016/j.mam.2014.12.003 · Cited by 403

Modulation of STAT signaling by STAT-interacting proteins

Shuai, K. (2000) · Oncogene · doi:10.1038/sj.onc.1203522 · Cited by 379

Biological control through regulated transcriptional coactivators

Spiegelman, B. M., & Heinrich, R. (2004) · Cell · doi:10.1016/j.cell.2004.09.037 · Cited by 377

Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of the Inducible Nitric Oxide Synthase Gene

Li, M., Pascual, G., & Glass, C. K. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.13.4699-4707.2000 · Cited by 377

The E6 protein of human papillomavirus type 16 binds to and inhibits co-activation by CBP and p300

Patel, D., Huang, S., Baglia, L. A., & McCance, D. J. (1999) · The EMBO Journal · doi:10.1093/emboj/18.18.5061 · Cited by 374

Linking β-Catenin to Androgen-signaling Pathway

Yang, F., Li, X., Sharma, M., Sasaki, C. Y., Longo, D. L., Lim, B., & Sun, Z. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m111962200 · Cited by 342

Nuclear Integration of Glucocorticoid Receptor and Nuclear Factor-κB Signaling by CREB-binding Protein and Steroid Receptor Coactivator-1

Sheppard, K.-A., Phelps, K. M., Williams, A. J., Thanos, D., Glass, C. K., Rosenfeld, M. G., Gerritsen, M. E., & Collins, T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29291 · Cited by 305

Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression

Schrem, H., Klempnauer, J., & Borlak, J. (2002) · Pharmacological Reviews · doi:10.1124/pr.54.1.129 · Cited by 283

A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition

Condon, J. C., Jeyasuria, P., Faust, J. M., Wilson, J. W., & Mendelson, C. R. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1633616100 · Cited by 270

The androgen receptor amino-terminal domain plays a key role in p160 coactivator-stimulated gene transcription

Alen, P., Claessens, F., Verhoeven, G., Rombauts, W., & Peeters, B. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.9.6085 · Cited by 268

Androgen receptor as a target in androgen-independent prostate cancer

Balk, S. P. (2002) · Urology · doi:10.1016/s0090-4295(02)01593-5 · Cited by 264

Oxygen-regulated and Transactivating Domains in Endothelial PAS Protein 1: Comparison with Hypoxia-inducible Factor-1α

O'Rourke, J. F., Tian, Y.-M., Ratcliffe, P. J., & Pugh, C. W. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.4.2060 · Cited by 242

A Paradigm for Gene Regulation: Inflammation, NF-κB and PPAR

Vanden Berghe, W., Vermeulen, L., Delerive, P., De Bosscher, K., Staels, B., & Haegeman, G. (2003) · Advances in experimental medicine and biology · doi:10.1007/978-1-4419-9072-3_22 · Cited by 222

PPARs and lipid ligands in inflammation and metabolism

Harmon, G. S., Lam, M. T., & Glass, C. K. (2011) · Chemical Reviews · doi:10.1021/cr2001355 · Cited by 216

Differential expression and regional distribution of steroid receptor coactivators SRC-1 and SRC-2 in brain and pituitary

Meijer, O. C., Steenbergen, P. J., & de Kloet, E. R. (2000) · Endocrinology · doi:10.1210/endo.141.6.7489 · Cited by 200

The nuclear receptor superfamily: a personal retrospect on the first two decades

Chambon, P. (2005) · Molecular Endocrinology · doi:10.1210/me.2005-0125 · Cited by 194

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

Wang, Y., Lonard, D. M., Yu, Y., Chow, D.-C., Palzkill, T. G., Wang, J., Qi, R., Matzuk, A. J., Song, X., Madoux, F., et al. (2014) · Cancer Research · doi:10.1158/0008-5472.can-13-2939 · Cited by 168

Recruitment of CREB Binding Protein Is Sufficient for CREB-Mediated Gene Activation

Cardinaux, J.-R., Notis, J. C., Zhang, Q., Vo, N., Craig, J. C., Fass, D. M., Brennan, R. G., & Goodman, R. H. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.5.1546-1552.2000 · Cited by 162

Down regulation of the interleukin-8 promoter by human papillomavirus type 16 E6 and E7 through effects on CREB binding protein/p300 and P/CAF

Huang, S.-M., & McCance, D. J. (2002) · Journal of Virology · doi:10.1128/jvi.76.17.8710-8721.2002 · Cited by 151

Receptor-interacting Protein 140 Directly Recruits Histone Deacetylases for Gene Silencing

Wei, L.-N., Hu, X., Chandra, D., Seto, E., & Farooqui, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004821200 · Cited by 150

SRC-1 and GRIP1 Coactivate Transcription with Hepatocyte Nuclear Factor 4

Wang, J.-C., Stafford, J. M., & Granner, D. K. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.47.30847 · Cited by 147

Glucocorticoids and the innate immune system: crosstalk with the toll-like receptor signaling network

Chinenov, Y., & Rogatsky, I. (2007) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2007.04.014 · Cited by 133

Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor.

Cheng, S., Brzostek, S., Lee, S. R., Hollenberg, A. N., & Balk, S. P. (2002) · Molecular Endocrinology · doi:10.1210/mend.16.7.0870 · Cited by 121

Nuclear receptor coactivators: structural and functional biochemistry

Bulynko, Y. A., & O’Malley, B. W. (2011) · Biochemistry · doi:10.1021/bi101762x · Cited by 113

Interleukin-4/STAT6 Represses STAT1 and NF-κB-dependent Transcription through Distinct Mechanisms

Ohmori, Y., & Hamilton, T. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006227200 · Cited by 106

Factor-specific modulation of CREB-binding protein acetyltransferase activity

Perissi, V., Dasen, J. S., Kurokawa, R., Wang, Z., Korzus, E., Rose, D. W., Glass, C. K., & Rosenfeld, M. G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.7.3652 · Cited by 104

Prolyl isomerase, Pin1: new findings of post-translational modifications and physiological substrates in cancer, asthma and Alzheimer’s disease

Takahashi, K., Uchida, C., Shin, R.-W., Shimazaki, K., & Uchida, T. (2008) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-007-7270-0 · Cited by 105

Functional Association between CBP and HNF4 inTrans-activation

Yoshida, E., Aratani, S., Itou, H., Miyagishi, M., Takiguchi, M., Osumu, T., Murakami, K., & Fukamizu, A. (1997) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.1997.7871 · Cited by 104

Concerted Activation of ETS Protein ER81 by p160 Coactivators, the Acetyltransferase p300 and the Receptor Tyrosine Kinase HER2/Neu

Goel, A., & Janknecht, R. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400036200 · Cited by 95

Regulation of Hepatocyte Thyroxine 5′-Deiodinase by T3 and Nuclear Receptor Coactivators as a Model of the Sick Euthyroid Syndrome

Yu, J., & Koenig, R. J. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004866200 · Cited by 94

Inactivation of the Nuclear Receptor Coactivator RAP250 in Mice Results in Placental Vascular Dysfunction

Antonson, P., Schuster, G. U., Wang, L., Rozell, B., Holter, E., Flodby, P., Treuter, E., Holmgren, L., & Gustafsson, J.-Å. (2003) · Molecular and Cellular Biology · doi:10.1128/mcb.23.4.1260-1268.2003 · Cited by 95

Competitive Cofactor Recruitment by Orphan Receptor Hepatocyte Nuclear Factor 4α1: Modulation by the F Domain

Ruse, M. D., Privalsky, M. L., & Sladek, F. M. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.6.1626-1638.2002 · Cited by 93

The use of phage display technique for the isolation of androgen receptor interacting peptides with (F/W)XXL(F/W) and FXXLY new signature motifs

Hsu, C.-L., Chen, Y.-L., Yeh, S., Ting, H.-J., Hu, Y.-C., Lin, H., Wang, X., & Chang, C. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m211908200 · Cited by 85

Familial/sporadic glucocorticoid resistance: clinical phenotype and molecular mechanisms

CHARMANDARI, E., KINO, T., & CHROUSOS, G. P. (2004) · Annals of the New York Academy of Sciences · doi:10.1196/annals.1321.014 · Cited by 76

Glucocorticoid and thyroid hormone receptors in mitochondria of animal cells

Scheller, K., Seibel, P., & Sekerist, C. E. (2003) · International review of cytology · doi:10.1016/s0074-7696(02)22011-2 · Cited by 73

cAMP response element-binding protein-binding protein mediates thyrotropin-releasing hormone signaling on thyrotropin subunit genes

Hashimoto, K., Zanger, K., Hollenberg, A. N., Cohen, L. E., Radovick, S., & Wondisford, F. E. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006819200 · Cited by 69

Something new to hang your HAT on

Montminy, M. (1997) · Nature · doi:10.1038/42594 · Cited by 59

The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells

Gizard, F., Lavallée, B., DeWitte, F., Teissier, E., Staels, B., & Hum, D. W. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205786200 · Cited by 58

The Nuclear Hormone Receptor Coactivator NRC Is a Pleiotropic Modulator Affecting Growth, Development, Apoptosis, Reproduction, and Wound Repair

Mahajan, M. A., Das, S., Zhu, H., Tomic-Canic, M., & Samuels, H. H. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.11.4994-5004.2004 · Cited by 55

A Novel Zinc Finger Protein TReP-132 Interacts with CBP/p300 to Regulate Human CYP11A1 Gene Expression

Gizard, F., Lavallée, B., DeWitte, F., & Hum, D. W. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m100113200 · Cited by 52

Nuclear receptor superfamily: Principles of signaling

Germain, P., Altucci, L., Bourguet, W., Rochette-Egly, C., & Gronemeyer, H. (2003) · Pure and Applied Chemistry · doi:10.1351/pac200375111619 · Cited by 53

p300 Regulates the Synergy of Steroidogenic Factor-1 and Early Growth Response-1 in Activating Luteinizing Hormone-β Subunit Gene

Mouillet, J.-F., Sonnenberg-Hirche, C., Yan, X., & Sadovsky, Y. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m312574200 · Cited by 51

Androgen receptor ligand-binding domain interaction and nuclear receptor specificity of FXXLF and LXXLL motifs as determined by L/F swapping

Dubbink, H. J., Hersmus, R., Pike, A. C. W., Molier, M., Brinkmann, A. O., Jenster, G., & Trapman, J. (2006) · Molecular Endocrinology · doi:10.1210/me.2005-0348 · Cited by 47

Unliganded Thyroid Hormone Receptor Regulates Metamorphic Timing via the Recruitment of Histone Deacetylase Complexes

Shi, Y.-B. (2013) · Current Topics in Developmental Biology · doi:10.1016/b978-0-12-396968-2.00010-5 · Cited by 46