Cited by 468

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Global analysis of genome, transcriptome and proteome reveals the response to aneuploidy in human cells

Stingele, Silvia, Stoehr, Gabriele, Peplowska, Karolina, Cox, Jürgen, Mann, Matthias, Storchova, Zuzana·2012·Molecular Systems Biology

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Crossref · 10.1038/msb.2012.40

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  • SQSTM1 overexpression at both gene and protein levels can be observed in muscle atrophy induced by cancer, though not by glucocorticoids, suggesting that the stimulus inducing autophagy may also be relevant to differential regulation of autophagy-related proteins.

    “Of interest, SQSTM1 overexpression at both the gene and protein levels can be observed in muscle atrophy induced by cancer, though not by glucocorticoids, suggesting that the stimulus inducing autophagy may also be relevant to the differential regulation of autophagy-related proteins [584].”

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Citations

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Research works printed but not linked: 27

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  2. Chen G, Bradford WD, Seidel CW, Li R (2012) Hsp90 stress potentiates rapid cellular adaptation through induction of aneuploidy. Nature 482: 246–250 · DOI · Paper page
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  7. Hassold T, Hall H, Hunt P (2007) The origin of human aneuploidy: where we have been, where we are going. Hum Mol Genet 16: R203–R208 · DOI
  8. Haugen AC, Goel A, Yamada K, Marra G, Nguyen TP, Nagasaka T, Kanazawa S, Koike J, Kikuchi Y, Zhong X, Arita M, Shibuya K, Oshimura M, Hemmi H, Boland CR, Koi M (2008) Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer. Cancer Res 68: 8465–8472 · DOI
  9. Huettel B, Kreil DP, Matzke M, Matzke AJ (2008) Effects of aneuploidy on genome structure, expression, and interphase organization in Arabidopsis thaliana. PLoS Genet 4: e1000226 · DOI
  10. Kvitek DJ, Will JL, Gasch AP (2008) Variations in stress sensitivity and genomic expression in diverse S. cerevisiae isolates. PLoS Genet 4: e1000223 · DOI
  11. Lamark T, Johansen T (2009) Autophagy: links with the proteasome. Curr Opin Cell Biol 22: 192–198 · DOI
  12. Makarevitch I, Phillips RL, Springer NM (2008) Profiling expression changes caused by a segmental aneuploid in maize. BMC Genomics 9: 7–16 · DOI
  13. Masramon L, Ribas M, Cifuentes P, Arribas R, García F, Egozcue J, Peinado MA, Miró R (2000) Cytogenetic characterization of two colon cell lines by using conventional G‐banding, comparative genomic hybridization, and whole chromosome painting. Cancer Genet Cytogenet 121: 17–21 · DOI
  14. Niwa O, Tange Y, Kurabayashi A (2006) Growth arrest and chromosome instability in aneuploid yeast. Yeast 23: 937–950 · DOI
  15. Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M (2002) Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Mol Cell Proteomics 1: 376–386 · DOI · Paper page
  16. Pavelka N, Rancati G, Zhu J, Bradford WD, Saraf A, Florens L, Sanderson BW, Hattem GL, Li R (2010) Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast. Nature 468: 321–325 · DOI · Paper page
  17. Ruepp A, Waegele B, Lechner M, Brauner B, Dunger‐Kaltenbach I, Fobo G, Frishman G, Montrone C, Mewes HW (2010) CORUM: the comprehensive resource of mammalian protein complexes‐‐2009. Nucleic Acids Res 38: D497–D501 · DOI
  18. Segal DJ, McCoy EE (1974) Studies on Down's syndrome in tissue culture. I. Growth rates and protein contents of fibroblast cultures. J Cell Physiol 83: 85–90 · DOI
  19. Selmecki A, Forche A, Berman J (2006) Aneuploidy and isochromosome formation in drug‐resistant Candida albicans. Science 313: 367–370 · DOI · Paper page
  20. Sheltzer JM, Blank HM, Pfau SJ, Tange Y, George BM, Humpton TJ, Brito IL, Hiraoka Y, Niwa O, Amon A (2011) Aneuploidy drives genomic instability in yeast. Science 333: 1026–1030 · DOI
  21. Stenberg P, Lundberg LE, Johansson A‐M, Rydén P, Svensson MJ, Larsson J (2009) Buffering of Segmental and Chromosomal Aneuploidies in Drosophila melanogaster. PLoS Genet 5: e1000465 · DOI
  22. Storchova Z, Pellman D (2004) From polyploidy to aneuploidy, genome instability and cancer. Nat Rev Mol Cell Biol 5: 45–54 · DOI
  23. Tang YC, Williams BR, Siegel JJ, Amon A (2011) Identification of aneuploidy‐selective antiproliferation compounds. Cell 144: 499–512 · DOI · Paper page
  24. Torres EM, Dephoure N, Panneerselvam A, Tucker CM, Whittaker CA, Gygi SP, Dunham MJ, Amon A (2010) Identification of aneuploidy‐tolerating mutations. Cell 143: 71–83 · DOI
  25. Torres EM, Sokolsky T, Tucker CM, Chan LY, Boselli M, Dunham MJ, Amon A (2007) Effects of aneuploidy on cellular physiology and cell division in haploid yeast. Science 317: 916–924 · DOI · Paper page
  26. Upender MB, Habermann JK, McShane LM, Korn EL, Barrett JC, Difilippantonio MJ, Ried T (2004) Chromosome transfer induced aneuploidy results in complex dysregulation of the cellular transcriptome in immortalized and cancer cells. Cancer Res 64: 6941–6949 · DOI
  27. Williams BR, Prabhu VR, Hunter KE, Glazier CM, Whittaker CA, Housman DE, Amon A (2008) Aneuploidy affects proliferation and spontaneous immortalization in mammalian cells. Science 322: 703–709 · DOI

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Metadata

Authors
Stingele, S., Stoehr, G., Peplowska, K., Cox, J., Mann, M., & Storchova, Z.
Venue
Molecular Systems Biology
Published
2012-09-11
Volume
8
Issue
1
ISSN
1744-4292
Cited by
468
References
8
Language
en

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