The DOI matches its Crossref record; 42 of the 42 references it cites were found in a registry or an index.
Local sleep in awake rats
Open accessAbstract
In an awake state, neurons in the cerebral cortex fire irregularly and electroencephalogram (EEG) recordings display low-amplitude, high-frequency fluctuations. During sleep, neurons oscillate between 'on' periods, when they fire as in an awake brain, and 'off' periods, when they stop firing altogether and the EEG displays high-amplitude slow waves. However, what happens to neuronal firing after a long period of being awake is not known. Here we show that in freely behaving rats after a long period in an awake state, cortical neurons can go briefly 'offline' as in sleep, accompanied by slow waves in the local EEG. Neurons often go offline in one cortical area but not in another, and during these periods of 'local sleep', the incidence of which increases with the duration of the awake state, rats are active and display an 'awake' EEG. However, they are progressively impaired in a sugar pellet reaching task. Thus, although both the EEG and behaviour indicate wakefulness, local populations of neurons in the cortex may be falling asleep, with negative consequences for performance.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“However, as distinct qualitative differences between both frequency bands have not been confirmed, the decrease in SWA across sleep appears to be most parsimoniously explained by a decrease in the incidence of high-amplitude slow waves (1267).”
From About Sleep's Role in Memory (2013) · cites this paper as [1267]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“in demonstrating that the encoding of information during waking enhances subsequent SWA in specific brain regions, these studies provide compelling evidence that SWA is regulated locally in addition to its global regulation by brain stem and diencephalic structures (672, 859, 975, 1267).”
From About Sleep's Role in Memory (2013) · cites this paper as [1267]
Experimental — accuracy not yet measuredThe source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“these studies provide compelling evidence that SWA is regulated locally in addition to its global regulation by brain stem and diencephalic structures (672, 859, 975, 1267).”
From About Sleep's Role in Memory (2013) · cites this paper as [1267]
Experimental — accuracy not yet measuredIn the citing paper
“Likewise, the intensity of slow waves in the cortical field potential slowly increases over the active period, in direct relationship to more frequent and longer sleep bouts”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Vyazovskiy et al., 2011
In the citing paper
“In addition to the phenomena described above, the degree of habituation to an experimental situation may also change the prevalence of low frequency rhythms in the cortex”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Vyazovskiy et al., 2011
In the citing paper
“In one recent study, the ability of animals to perform a difficult pellet retrieval task was significantly impaired during the appearance of Off periods in cortical networks, supporting the hypothesis that these sudden, but brief, cessations of cortical activity are detrimental to behaviorally relevant cortical operation (Vyazovskiy et al., 2011)”
From Waking state: rapid variations modulate neural and behavioral responses (2015) · cites this paper as Vyazovskiy et al., 2011
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Diekelmann, S., & Born, J. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2762 · Cited by 3,760
An Energy Budget for Signaling in the Grey Matter of the Brain
Attwell, D., & Laughlin, S. B. (2001) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1097/00004647-200110000-00001 · Cited by 3,543
Van Dongen, H. P. A., Maislin, G., Mullington, J. M., & Dinges, D. F. (2003) · Sleep · doi:10.1093/sleep/26.2.117 · Cited by 3,173
Sleep function and synaptic homeostasis
Tononi, G., & Cirelli, C. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.05.002 · Cited by 2,151
Self-citationHuber, R., Felice Ghilardi, M., Massimini, M., & Tononi, G. (2004) · Nature · doi:10.1038/nature02663 · Cited by 1,854
Self-citationSleep Homeostasis and Models of Sleep Regulation
Borb, A. A., & Achermann, P. (1999) · Journal of Biological Rhythms · doi:10.1177/074873099129000894 · Cited by 1,546
Effects of sleep deprivation on cognition
Killgore, W. D. S. (2010) · Progress in Brain Research · doi:10.1016/b978-0-444-53702-7.00007-5 · Cited by 1,421
Natural waking and sleep states: a view from inside neocortical neurons
Steriade, M., Timofeev, I., & Grenier, F. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.5.1969 · Cited by 1,296
Learning-Induced LTP in Neocortex
Rioult-Pedotti, M.-S., Friedman, D. J., & Donoghue, J. P. (2000) · Science · doi:10.1126/science.290.5491.533 · Cited by 1,014
Regional Slow Waves and Spindles in Human Sleep
Nir, Y., Staba, R. J., Andrillon, T., Vyazovskiy, V. V., Cirelli, C., Fried, I., & Tononi, G. (2011) · Neuron · doi:10.1016/j.neuron.2011.02.043 · Cited by 924
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 852
Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex
Rocchi, F., Canella, C., Noei, S., Gutierrez‐Barragan, D., Coletta, L., Galbusera, A., Stuefer, A., Vassanelli, S., Pasqualetti, M., Iurilli, G., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28591-3 · Cited by 121
A Neocortical Delta Rhythm Facilitates Reciprocal Interlaminar Interactions via Nested Theta Rhythms
Carracedo, L. M., Kjeldsen, H., Cunnington, L. G., Jenkins, A., Schofield, I. S., Cunningham, M. O., Davies, C. H., Traub, R. D., & Whittington, M. A. (2013) · Journal of Neuroscience · doi:10.1523/jneurosci.0735-13.2013 · Cited by 114
Sleep–Wake Cycle in Young and Older Mice
Soltani, S., Chauvette, S., Bukhtiyarova, O., Lina, J., Dubé, J., Seigneur, J., Carrier, J., & Timofeev, I. (2019) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2019.00051 · Cited by 121
Dietary Therapy Mitigates Persistent Wake Deficits Caused by Mild Traumatic Brain Injury
Lim, M. M., Elkind, J., Xiong, G., Galante, R., Zhu, J., Zhang, L., Lian, J., Rodin, J., Kuzma, N. N., Pack, A. I., et al. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3007092 · Cited by 113
Neurobiological studies of fatigue
Harrington, M. E. (2012) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2012.07.004 · Cited by 112
“Sleep deprivation leads to increased theta power in the EEG (Vyazovskiy and Tobler, 2005) and periods of reduced neural activity in cortical areas during waking (Vyazovskiy et al., 2011).”
Local sleep spindle modulations in relation to specific memory cues
Cox, R., Hofman, W. F., de Boer, M., & Talamini, L. M. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2014.05.028 · Cited by 118
Gating and the Need for Sleep: Dissociable Effects of Adenosine A1 and A2A Receptors
Lazarus, M., Oishi, Y., Bjorness, T. E., & Greene, R. W. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00740 · Cited by 110
Lempel-Ziv complexity of cortical activity during sleep and waking in rats
Abásolo, D., Simons, S., da Silva, R. M., Tononi, G., & Vyazovskiy, V. V. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00575.2014 · Cited by 112
Self-citationHippocampal sleep spindles preceding neocortical sleep onset in humans
Sarasso, S., Proserpio, P., Pigorini, A., Moroni, F., Ferrara, M., De Gennaro, L., De Carli, F., Lo Russo, G., Massimini, M., & Nobili, L. (2014) · NeuroImage · doi:10.1016/j.neuroimage.2013.10.031 · Cited by 105
Sleep in vertebrate and invertebrate animals, and insights into the function and evolution of sleep
Miyazaki, S., Liu, C.-Y., & Hayashi, Y. (2017) · Neuroscience Research · doi:10.1016/j.neures.2017.04.017 · Cited by 112
Porkka‐Heiskanen, T. (2013) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2013.02.010 · Cited by 114
Morning-evening variation in human brain metabolism and memory circuits
Shannon, B., Dosenbach, R. A. T., Su, Y., Vlassenko, A. G., Larson‐Prior, L. J., Nolan, T. S., Snyder, A. Z., & Raichle, M. E. (2012) · Journal of Neurophysiology · doi:10.1152/jn.00651.2012 · Cited by 108
Cortex-wide BOLD fMRI activity reflects locally-recorded slow oscillation-associated calcium waves
Schwalm, M., Schmid, F., Wachsmuth, L., Backhaus, H., Kronfeld, A., Aedo-Jury, F., Prouvot, P.-H., Fois, C., Albers, F., van Alst, T. M., et al. (2017) · eLife · doi:10.7554/elife.27602 · Cited by 106
Nobili, L., De Gennaro, L., Proserpio, P., Moroni, F., Sarasso, S., Pigorini, A., De Carli, F., & Ferrara, M. (2012) · Progress in Brain Research · doi:10.1016/b978-0-444-59427-3.00013-7 · Cited by 100
Dreams and nightmares in healthy adults and in patients with sleep and neurological disorders
Siclari, F., Valli, K., & Arnulf, I. (2020) · The Lancet Neurology · doi:10.1016/s1474-4422(20)30275-1 · Cited by 98
Cell-Type-Specific Optical Recording of Membrane Voltage Dynamics in Freely Moving Mice
Marshall, J. D., Li, J. Z., Zhang, Y., Gong, Y., St-Pierre, F., Lin, M. Z., & Schnitzer, M. J. (2016) · Cell · doi:10.1016/j.cell.2016.11.021 · Cited by 97
Kinase signalling in excitatory neurons regulates sleep quantity and depth
Kim, S. J., Hotta-Hirashima, N., Asano, F., Kitazono, T., Iwasaki, K., Nakata, S., Komiya, H., Asama, N., Matsuoka, T., Fujiyama, T., et al. (2022) · Nature · doi:10.1038/s41586-022-05450-1 · Cited by 96
Slow Oscillations during Sleep Coordinate Interregional Communication in Cortical Networks
Cox, R., van Driel, J., de Boer, M., & Talamini, L. M. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1953-14.2014 · Cited by 103
Sleep: a synchrony of cell activity‐driven small network states
Krueger, J. M., Huang, Y. H., Rector, D. M., & Buysse, D. J. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12238 · Cited by 98
The Theta Paradox: 4-8 Hz EEG Oscillations Reflect Both Sleep Pressure and Cognitive Control
Snipes, S., Krugliakova, E., Meier, E., & Huber, R. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.1063-22.2022 · Cited by 108
Novati, A., Hulshof, H. J., Koolhaas, J. M., Lucassen, P. J., & Meerlo, P. (2011) · Neuroscience · doi:10.1016/j.neuroscience.2011.06.027 · Cited by 99
Regulation of neuron-astrocyte metabolic coupling across the sleep-wake cycle
Petit, J.-M., & Magistretti, P. J. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2015.12.007 · Cited by 92
D'Rozario, A. L., Cross, N. E., Vakulin, A., Bartlett, D. J., WONG, K. K. H., Wang, D., & Grunstein, R. R. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.10.003 · Cited by 92
Heterogeneity of arousals in human sleep: A stereo-electroencephalographic study
Peter‐Derex, L., Magnin, M., & Bastuji, H. (2015) · NeuroImage · doi:10.1016/j.neuroimage.2015.07.057 · Cited by 95
Understanding the Need for Sleep to Improve Cognition
Leong, R. L. F., & Chee, M. W. L. (2022) · Annual Review of Psychology · doi:10.1146/annurev-psych-032620-034127 · Cited by 95
Modeling Resting-State Functional Networks When the Cortex Falls Asleep: Local and Global Changes
Deco, G., Hagmann, P., Hudetz, A. G., & Tononi, G. (2013) · Cerebral Cortex · doi:10.1093/cercor/bht176 · Cited by 93
Self-citationThe Roles of Cortical Slow Waves in Synaptic Plasticity and Memory Consolidation
Miyamoto, D., Hirai, D., & Murayama, M. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00092 · Cited by 97
How the Human Brain Sleeps: Direct Cortical Recordings of Normal Brain Activity
von Ellenrieder, N., Gotman, J., Zelmann, R., Rogers, C., Nguyen, D. K., Kahane, P., Dubeau, F., & Frauscher, B. (2019) · Annals of Neurology · doi:10.1002/ana.25651 · Cited by 91
Raccuglia, D., Huang, S., Ender, A., Heim, M. ‐., Laber, D., Suárez-Grimalt, R., Liotta, A., Sigrist, S. J., Geiger, J. R. P., & Owald, D. (2019) · Current Biology · doi:10.1016/j.cub.2019.08.070 · Cited by 89
Satterfield, B. C., & Dongen, H. P. A. V. (2013) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2013.798923 · Cited by 88
The sleep relay—the role of the thalamus in central and decentral sleep regulation
Coulon, P., Budde, T., & Pape, H. (2011) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-011-1014-6 · Cited by 87
Circadian dynamics in measures of cortical excitation and inhibition balance
Chellappa, S. L., Gaggioni, G., Ly, J. Q. M., Papachilleos, S., Borsu, C., Brzozowski, A., Rosanova, M., Sarasso, S., Luxen, A., Middleton, B., et al. (2016) · Scientific Reports · doi:10.1038/srep33661 · Cited by 84
Spatio-temporal properties of sleep slow waves and implications for development
Timofeev, I., Schoch, S. F., LeBourgeois, M. K., Huber, R., Riedner, B. A., & Kurth, S. (2020) · Current Opinion in Physiology · doi:10.1016/j.cophys.2020.01.007 · Cited by 83
Spoormaker, V. I., Gleiser, P. M., & Czisch, M. (2012) · Frontiers in Neurology · doi:10.3389/fneur.2012.00080 · Cited by 83
Neuronal Cascades Shape Whole-Brain Functional Dynamics at Rest
Rabuffo, G., Fousek, J., Bernard, C., & Jirsa, V. (2021) · eNeuro · doi:10.1523/eneuro.0283-21.2021 · Cited by 91
EEG slow waves in traumatic brain injury: Convergent findings in mouse and man
Modarres, M. H., Kuzma, N. N., Kretzmer, T. S., Pack, A. I., & Lim, M. M. (2016) · Neurobiology of Sleep and Circadian Rhythms · doi:10.1016/j.nbscr.2016.06.001 · Cited by 87
Tossell, K., Yu, X., Giannos, P., Soto, B. A., Nollet, M., Yustos, R., Miracca, G., Vicente, M., Miao, A., Hsieh, B., et al. (2023) · Nature Neuroscience · doi:10.1038/s41593-023-01430-4 · Cited by 86
Origins and consequences of cognitive fatigue
Pessiglione, M., Blain, B., Wiehler, A., & Naik, S. (2025) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2025.02.005 · Cited by 82
Chee, M. W. L., Goh, C. S. F., Namburi, P., Parimal, S., Seidl, K. N., & Kastner, S. (2011) · NeuroImage · doi:10.1016/j.neuroimage.2011.06.058 · Cited by 81
Effects of Aging on Cortical Neural Dynamics and Local Sleep Homeostasis in Mice
McKillop, L. E., Fisher, S. P., Cui, N., Peirson, S. N., Foster, F., Wafford, K. A., & Vyazovskiy, V. V. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.2513-17.2018 · Cited by 86
Self-citationTo sleep or not to sleep: neuronal and ecological insights
Eban-Rothschild, A., Giardino, W. J., & de Lecea, L. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.04.010 · Cited by 80
Human REM sleep recalibrates neural activity in support of memory formation
Lendner, J. D., Niethard, N., Mander, B. A., van Schalkwijk, F. J., Schuh‐Hofer, S., Schmidt, H., Knight, R. T., Jan Born, A., Walker, M. P., Lin, J. J., et al. (2023) · Science Advances · doi:10.1126/sciadv.adj1895 · Cited by 82
Bushey, D., Tononi, G., & Cirelli, C. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1419603112 · Cited by 82
Self-citationTanabe, S., Huang, Z., Zhang, J., Chen, Y., Fogel, S. M., Doyon, J., Wu, J., Xu, J., Zhang, J., Qin, P., et al. (2020) · Anesthesiology · doi:10.1097/aln.0000000000003197 · Cited by 78
Topographic sleep EEG changes in the acute and chronic stage of hemispheric stroke
Poryazova, R., Huber, R., Khatami, R., Werth, E., Brugger, P., Barath, K., Baumann, C. R., & Bassetti, C. L. (2014) · Journal of Sleep Research · doi:10.1111/jsr.12208 · Cited by 79
Barf, R. P., Van Dijk, G., Scheurink, A. J. W., Hoffmann, K., Novati, A., Hulshof, H. J., Fuchs, E., & Meerlo, P. (2012) · Physiology & Behavior · doi:10.1016/j.physbeh.2012.09.005 · Cited by 77
Sleep loss diminishes hippocampal reactivation and replay
Giri, B. K., Kinsky, N. R., Kaya, U., Maboudi, K., Abel, T. G., & Diba, K. (2024) · Nature · doi:10.1038/s41586-024-07538-2 · Cited by 79
Tracking the Sleep Onset Process: An Empirical Model of Behavioral and Physiological Dynamics
Prerau, M. J., Hartnack, K. E., Obregon-Henao, G., Sampson, A. L., Merlino, M., Gannon, K., Bianchi, M. T., Ellenbogen, J. M., & Purdon, P. L. (2014) · PLoS Computational Biology · doi:10.1371/journal.pcbi.1003866 · Cited by 77
Rodriguez, A. V., Funk, C. M., Vyazovskiy, V. V., Nir, Y., Tononi, G., & Cirelli, C. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1614-16.2016 · Cited by 76
Self-citationA single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice
Honda, T., Fujiyama, T., Miyoshi, C., Ikkyu, A., Hotta-Hirashima, N., Kanno, S., Mizuno, S., Sugiyama, F., Takahashi, S., Funato, H., et al. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1810823115 · Cited by 76
Offline memory consolidation during waking rest
Wamsley, E. J. (2022) · Nature Reviews Psychology · doi:10.1038/s44159-022-00072-w · Cited by 84
Slow Waves Promote Sleep-Dependent Plasticity and Functional Recovery after Stroke
Facchin, L., Schöne, C., Mensen, A., Bandarabadi, M., Pilotto, F., Saxena, S., Libourel, P., Bassetti, C. L., & Adamantidis, A. (2020) · Journal of Neuroscience · doi:10.1523/jneurosci.0373-20.2020 · Cited by 79
Apical drive-A cellular mechanism of dreaming?
Aru, J., Siclari, F., Phillips, W. A., & Storm, J. F. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.09.018 · Cited by 74
Claustrum neurons projecting to the anterior cingulate restrict engagement during sleep and behavior
Atlan, G., Matosevich, N., Peretz‐Rivlin, N., Marsh‐Yvgi, I., Zelinger, N., Chen, E., Kleinman, T., Bleistein, N., Sheinbach, E., Groysman, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-48829-6 · Cited by 77
Self-citationIs criticality a unified setpoint of brain function?
Hengen, K. B., & Shew, W. L. (2025) · Neuron · doi:10.1016/j.neuron.2025.05.020 · Cited by 80
Physiologically-based modeling of sleep–wake regulatory networks
Booth, V., & Behn, C. D. (2014) · Mathematical Biosciences · doi:10.1016/j.mbs.2014.01.012 · Cited by 75
Sleep Patterns and Homeostatic Mechanisms in Adolescent Mice
Nelson, A. B., Faraguna, U., Zoltan, J., Tononi, G., & Cirelli, C. (2013) · Brain Sciences · doi:10.3390/brainsci3010318 · Cited by 74
Self-citationBeaman, C. B., Eagleman, S. L., & Dragoi, V. (2017) · Nature Communications · doi:10.1038/s41467-017-01030-4 · Cited by 80
REM sleep is associated with distinct global cortical dynamics and controlled by occipital cortex
Wang, Z., Fei, X., Liu, X., Wang, Y., Hu, Y., Peng, W., Wang, Y.-W., Zhang, S., & Xu, M. (2022) · Nature Communications · doi:10.1038/s41467-022-34720-9 · Cited by 73
The inescapable drive to sleep: Overlapping mechanisms of sleep and sedation
Franks, N. P., & Wisden, W. (2021) · Science · doi:10.1126/science.abi8372 · Cited by 74
Behavioral and Electrophysiological Correlates of Sleep and Sleep Homeostasis
Deboer, T. (2013) · Current topics in behavioral neurosciences · doi:10.1007/7854_2013_248 · Cited by 73
Scalp and Source Power Topography in Sleepwalking and Sleep Terrors: A High-Density EEG Study
Castelnovo, A., Riedner, B. A., Smith, R. F., Tononi, G., Boly, M., & Benca, R. M. (2016) · Sleep · doi:10.5665/sleep.6162 · Cited by 72
Self-citationSleep-Active Neurons: Conserved Motors of Sleep
Bringmann, H. (2018) · Genetics · doi:10.1534/genetics.117.300521 · Cited by 74
Microglia dynamics in sleep/wake states and in response to sleep loss
Deurveilher, S., Golovin, T., Hall, S., & Semba, K. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104944 · Cited by 75
Region-Specific Dissociation between Cortical Noradrenaline Levels and the Sleep/Wake Cycle
Bellesi, M., Tononi, G., Cirelli, C., & Serra, P. A. (2015) · SLEEP · doi:10.5665/sleep.5336 · Cited by 80
Self-citationMicrosleep episodes in the borderland between wakefulness and sleep.
Hertig-Godeschalk, A., Skorucak, J., Malafeev, A., Achermann, P., Mathis, J., & Schreier, D. (2019) · Sleep · doi:10.1093/sleep/zsz163 · Cited by 72
Reimann, H. M., & Niendorf, T. (2020) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2020.00008 · Cited by 75
Perogamvros, L., Baird, B., Seibold, M., Riedner, B., Boly, M., & Tononi, G. (2017) · Journal of Cognitive Neuroscience · doi:10.1162/jocn_a_01155 · Cited by 70
Self-citationTononi, G., Boly, M., & Cirelli, C. (2024) · Neuron · doi:10.1016/j.neuron.2024.04.011 · Cited by 70
Self-citationStereotypic wheel running decreases cortical activity in mice
Fisher, S. P., Cui, N., McKillop, L. E., Gemignani, J., Bannerman, D. M., Oliver, P. L., Peirson, S. N., & Vyazovskiy, V. V. (2016) · Nature Communications · doi:10.1038/ncomms13138 · Cited by 70
Self-citationIntracellular chloride regulation mediates local sleep pressure in the cortex
Alfonsa, H., Burman, R. J., Brodersen, P. J. N., Newey, S. E., Mahfooz, K., Yamagata, T., Panayi, M. C., Bannerman, D. M., Vyazovskiy, V. V., & Akerman, C. J. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01214-2 · Cited by 72
Self-citationThe Circadian Control of Sleep
Fisher, S. P., Foster, F., & Peirson, S. N. (2013) · Handbook of experimental pharmacology · doi:10.1007/978-3-642-25950-0_7 · Cited by 75
Sharpless, B. A. (2014) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2014.03.001 · Cited by 70
Dynamic modulation of theta–gamma coupling during rapid eye movement sleep
Bandarabadi, M., Boyce, R., Herrera, C. G., Bassetti, C. L., Williams, S., Schindler, K. A., & Adamantidis, A. (2019) · SLEEP · doi:10.1093/sleep/zsz182 · Cited by 75
Lunsford‐Avery, J. R., Damme, K. S. F., Engelhard, M., Kollins, S. H., & Mittal, V. A. (2020) · Scientific Reports · doi:10.1038/s41598-019-57024-3 · Cited by 69
Functional connectivity and the sleep-deprived brain
Chee, M. W. L., & Zhou, J. (2019) · Progress in brain research · doi:10.1016/bs.pbr.2019.02.009 · Cited by 68
Bassetti, C. L., Ferini‐Strambi, L., Brown, S. A., Adamantidis, A., Benedetti, F., Bruni, O., Cajochen, C., Dolenc‐Grošelj, L., Ferri, R., Gais, S., et al. (2015) · European Journal of Neurology · doi:10.1111/ene.12781 · Cited by 75
Sleep-like cortical dynamics during wakefulness and their network effects following brain injury
Massimini, M., Corbetta, M., Sanchez-Vives, M. V., Andrillon, T., Deco, G., Rosanova, M., & Sarasso, S. (2024) · Nature Communications · doi:10.1038/s41467-024-51586-1 · Cited by 76
Glycogen metabolism and the homeostatic regulation of sleep
Petit, J.-M., Burlet-Godinot, S., Magistretti, P. J., & Allaman, I. (2014) · Metabolic Brain Disease · doi:10.1007/s11011-014-9629-x · Cited by 79
Recent advances in understanding the roles of hypocretin/orexin in arousal, affect, and motivation
Nevárez, N., & de Lecea, L. (2018) · F1000Research · doi:10.12688/f1000research.15097.1 · Cited by 67
Large-scale structure and individual fingerprints of locally coupled sleep oscillations
Cox, R., Mylonas, D., Manoach, D. S., & Stickgold, R. (2018) · SLEEP · doi:10.1093/sleep/zsy175 · Cited by 74
Arena, A., Comolatti, R., Thon, S., Casali, A. G., & Storm, J. F. (2021) · eneuro · doi:10.1523/eneuro.0343-20.2021 · Cited by 66
Local Use-Dependent Sleep in Wakefulness Links Performance Errors to Learning
Quercia, A., Zappasodi, F., Committeri, G., & Ferrara, M. (2018) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2018.00122 · Cited by 70
Someren, E. J. W. V., Oosterman, J. M., van Harten, B., Vogels, R. L. C., Gouw, A. A., Weinstein, H. C., Poggesi, A., Scheltens, P., & Scherder, E. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.05.017 · Cited by 66
fMRI spectral signatures of sleep
Song, C., Boly, M., Tagliazucchi, E., Laufs, H., & Tononi, G. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2016732119 · Cited by 65
Self-citationDeciphering Neural Codes of Memory during Sleep
Chen, Z. S., & Wilson, M. A. (2017) · Trends in Neurosciences · doi:10.1016/j.tins.2017.03.005 · Cited by 65
Focal lesions induce large-scale percolation of sleep-like intracerebral activity in awake humans
Russo, S., Pigorini, A., Mikulan, E., Sarasso, S., Rubino, A., Zauli, F. M., Parmigiani, S., d’Orio, P., Cattani, A., Francione, S., et al. (2021) · NeuroImage · doi:10.1016/j.neuroimage.2021.117964 · Cited by 64
Optimizing detection and analysis of slow waves in sleep EEG
Mensen, A., Riedner, B. A., & Tononi, G. (2016) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2016.09.006 · Cited by 68
Self-citationTired and misconnected: A breakdown of brain modularity following sleep deprivation
Simon, E. B., Maron‐Katz, A., Lahav, N., Ron Shamir, A., & Hendler, T. (2017) · Human Brain Mapping · doi:10.1002/hbm.23596 · Cited by 64
Predicting dream recall: EEG activation during NREM sleep or shared mechanisms with wakefulness?
Scarpelli, S., D’Atri, A., Mangiaruga, A., Marzano, C., Gorgoni, M., Schiappa, C., Ferrara, M., & De Gennaro, L. (2017) · Brain Topography · doi:10.1007/s10548-017-0563-1 · Cited by 63
Neuroscience-driven discovery and development of sleep therapeutics
Dresler, M., Spoormaker, V. I., Beitinger, P., Czisch, M., Kimura, M., Steiger, A., & Holsboer, F. (2014) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2013.10.012 · Cited by 63
Lambert, I., Roehri, N., Giusiano, B., Carron, R., Wendling, F., Bénar, C., & Bartoloméi, F. (2017) · Epilepsia · doi:10.1111/epi.13958 · Cited by 63
Three brain states in the hippocampus and cortex
Kay, K., & Frank, L. M. (2018) · Hippocampus · doi:10.1002/hipo.22956 · Cited by 69
Stochastic transitions into silence cause noise correlations in cortical circuits
Mochol, G., Hermoso-Mendizabal, A., Sakata, S., Harris, K. D., & de la Rocha, J. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1410509112 · Cited by 62
Espie, C. A., Pawlecki, B., Waterfield, D., Fitton, K., Radocchia, M., & Luik, A. I. (2018) · Sleep Health · doi:10.1016/j.sleh.2018.03.003 · Cited by 62
Delta rhythm in wakefulness: evidence from intracranial recordings in human beings
Sachdev, R. N. S., Gaspard, N., Gerrard, J. L., Hirsch, L. J., Spencer, D. D., & Zaveri, H. P. (2015) · Journal of Neurophysiology · doi:10.1152/jn.00249.2015 · Cited by 62
Cognitive processing during the transition to sleep.
Goupil, L., & Bekinschtein, T. A. (2012) · PubMed · doi:10.4449/aib.v150i2.1247 · Cited by 60
Einstein, M., Polack, P., Tran, D. T., & Golshani, P. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3868-16.2017 · Cited by 62
Validation of an automated sleep spindle detection method for mouse electroencephalography
Uygun, D. S., Katsuki, F., Bolortuya, Y., Aguilar, D. D., McKenna, J. T., Thankachan, S., McCarley, R. W., Basheer, R., Brown, R. E., Strecker, R. E., et al. (2018) · SLEEP · doi:10.1093/sleep/zsy218 · Cited by 60
Humanely Ending the Life of Animals: Research Priorities to Identify Alternatives to Carbon Dioxide
Steiner, A. R., Flammer, S. A., Beausoleil, N. J., Berg, C., Bettschart‐Wolfensberger, R., Pinillos, R. G., Golledge, H., Marahrens, M., Meyer, R., Schnitzer, T. K., et al. (2019) · Animals · doi:10.3390/ani9110911 · Cited by 68
Metadata
- Authors
- Vyazovskiy, V. V., Olcese, U., Hanlon, E. C., Nir, Y., Cirelli, C., & Tononi, G.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Tononi, Giulio
- Venue
- Nature
- Published
- 2011-04
- Volume
- 472
- Issue
- 7344
- Pages
- 443-447
- ISSN
- 0028-0836 (ISSN-L)
- 1476-4687
- PMC
- PMC3085007
- OpenAlex
- W2039029351
- Cited by
- 865
- References
- 42
- Citations by year
- 2026: 55 · 2025: 72 · 2024: 58 · 2023: 54 · 2022: 64 · 2021: 65 · 2020: 73 · 2019: 73 · 2018: 53 · 2017: 62 · 2016: 50 · 2015: 36 · 2014: 45 · 2013: 46 · 2012: 39
- FWCI
- 24.07
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- www.springer.com/tdm (tdm)
- Locations
- Nature (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Surrey Research Insight Open Access (The University of Surrey) (submittedVersion)
- RePEc: Research Papers in Economics (submittedVersion)
- Open Research (University of Surrey) (submittedVersion)
- Funders
- National Institutes of Health (5p20mh077967-04, DP1OD000579)
- National Institute of Mental Health (P20MH-077967)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
- Keywords
- local sleep, cortical neuronal activity, slow waves, EEG, wakefulness, prolonged wakefulness, sleep-like state, cognitive impairment, rats, sleep-wake transition
- MeSH terms
- Action Potentials, Animals, Behavior, Animal, Cerebral Cortex, Electroencephalography, Male, Models, Neurological, Rats, Inbred WKY, Reward, Sleep, Sleep Deprivation, Wakefulness, Rats
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
