Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

Alternative activation of macrophages

Gordon, S. (2003) · Nature Reviews Immunology · doi:10.1038/nri978 · Cited by 6,189 · see citing works

Nitric oxide and the immune response

Bogdan, C. (2001) · Nature Immunology · doi:10.1038/ni1001-907 · Cited by 3,447 · see citing works

Recognition of microorganisms and activation of the immune response

Medzhitov, R. (2007) · Nature · doi:10.1038/nature06246 · Cited by 2,862 · see citing works

Regulation of immune responses by L-arginine metabolism

Bronte, V., & Zanovello, P. (2005) · Nature Reviews Immunology · doi:10.1038/nri1668 · Cited by 1,775 · see citing works

Fibrotic disease and the TH1/TH2 paradigm

Wynn, T. A. (2004) · Nature Reviews Immunology · doi:10.1038/nri1412 · Cited by 1,765 · see citing works

Host Defense Mechanisms Triggered by Microbial Lipoproteins Through Toll-Like Receptors

Brightbill, H. D., Libraty, D. H., Krutzik, S. R., Yang, R., Belisle, J. T., Bleharski, J. R., Maitland, M. L., Norgard, M. V., Plevy, S. E., Smale, S. T., et al. (1999) · Science · doi:10.1126/science.285.5428.732 · Cited by 1,659 · see citing works

Transcriptional Adaptation of <i>Mycobacterium tuberculosis</i> within Macrophages

Schnappinger, D., Ehrt, S., Voskuil, M. I., Liu, Y., Mangan, J. A., Monahan, I. M., Dolganov, G., Efron, B., Butcher, P. D., Nathan, C., et al. (2003) · The Journal of Experimental Medicine · doi:10.1084/jem.20030846 · Cited by 1,420 · see citing works

Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation

Vats, D., Mukundan, L., Odegaard, J. I., Zhang, L., Smith, K. L., Morel, C. R., Greaves, D. R., Murray, P. J., & Chawla, A. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.05.011 · Cited by 1,369 · see citing works

The JAK-STAT Signaling Pathway: Input and Output Integration

Murray, P. J. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.5.2623 · Cited by 1,179 · see citing works

Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages.

Chan, J., Xing, Y., Magliozzo, R. S., & Bloom, B. R. (1992) · The Journal of Experimental Medicine · doi:10.1084/jem.175.4.1111 · Cited by 1,062 · see citing works

Protective immune mechanisms in helminth infection

Anthony, R. M., Rutitzky, L. I., Urban, J. F., Stadecker, M. J., & Gause, W. C. (2007) · Nature reviews. Immunology · doi:10.1038/nri2199 · Cited by 929 · see citing works

Induction of Direct Antimicrobial Activity Through Mammalian Toll-Like Receptors

Thoma-Uszynski, S., Stenger, S., Takeuchi, O., Ochoa, M. T., Engele, M., Sieling, P. A., Barnes, P. F., Röllinghoff, M., Bölcskei, P., Wagner, M., et al. (2001) · Science · doi:10.1126/science.291.5508.1544 · Cited by 729 · see citing works

Alternative Metabolic States in Murine Macrophages Reflected by the Nitric Oxide Synthase/Arginase Balance: Competitive Regulation by CD4+ T Cells Correlates with Th1/Th2 Phenotype

Munder, M., Eichmann, K., & Modolell, M. (1998) · The Journal of Immunology · doi:10.4049/jimmunol.160.11.5347 · Cited by 647 · see citing works

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

Saeij, J. P. J., Coller, S. P., Boyle, J. P., Jerome, M. E., White, M. W., & Boothroyd, J. C. (2006) · Nature · doi:10.1038/nature05395 · Cited by 585 · see citing works

Th1/Th2-Regulated Expression of Arginase Isoforms in Murine Macrophages and Dendritic Cells

Munder, M., Eichmann, K., Morán, J. M., Centeno, F., Soler, G., & Modolell, M. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.163.7.3771 · Cited by 561 · see citing works

Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Guerin mutants that secrete listeriolysin

Grode, L. (2005) · Journal of Clinical Investigation · doi:10.1172/jci24617 · Cited by 557 · see citing works

Reciprocal regulation of the nitric oxide synthase/arginase balance in mouse bone marrow‐derived macrophages by TH 1 and TH 2 cytokines

Modolell, M., Corraliza, I. M., Link, F., Soler, G., & Eichmann, K. (1995) · European Journal of Immunology · doi:10.1002/eji.1830250436 · Cited by 554 · see citing works

RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

Park, J., Kim, Y., McDonald, C., Kanneganti, T., Hasegawa, M., Body–Malapel, M., Inohara, N., & Núñez, G. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.178.4.2380 · Cited by 532 · see citing works

Persistent activation of an innate immune response translates respiratory viral infection into chronic lung disease

Kim, E. Y., Battaile, J. T., Patel, A. C., You, Y., Agapov, E., Grayson, M. H., Benoit, L. A., Byers, D. E., Alevy, Y., Tucker, J., et al. (2008) · Nature Medicine · doi:10.1038/nm1770 · Cited by 523 · see citing works

Cutting Edge: Toll-Like Receptor (TLR)2- and TLR4-Mediated Pathogen Recognition in Resistance to Airborne Infection with Mycobacterium tuberculosis

Reiling, N., Hölscher, C., Fehrenbach, A., Kröger, S., Kirschning, C. J., Goyert, S. M., & Ehlers, S. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.169.7.3480 · Cited by 463 · see citing works

SOCS3 regulates the plasticity of gp130 signaling

Lang, R., Pauleau, A.-L., Parganas, E., Takahashi, Y., Mages, J., Ihle, J. N., Rutschman, R., & Murray, P. J. (2003) · Nature Immunology · doi:10.1038/ni932 · Cited by 439 · see citing works

Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen Toxoplasma gondii

Scharton‐Kersten, T., Yap, G. S., Magram, J., & Sher, A. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.185.7.1261 · Cited by 423 · see citing works

Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival

Gobert, A. P., McGee, D. J., Akhtar, M., Mendz, G. L., Newton, J. C., Cheng, Y., Mobley, H. L. T., & Wilson, K. T. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.241443798 · Cited by 380 · see citing works

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

Karaghiosoff, M., Steinborn, R., Kovarik, P., Kriegshäuser, G., Baccarini, M., Donabauer, B., Reichart, U., Kolbe, T., Bogdan, C., Leanderson, T., et al. (2003) · Nature Immunology · doi:10.1038/ni910 · Cited by 363 · see citing works

Tissue‐Specific Contributions of Pneumococcal Virulence Factors to Pathogenesis

Orihuela, C. J., Gao, G., Francis, K. P., Yu, J., & TUOMANEN, E. I. (2004) · The Journal of Infectious Diseases · doi:10.1086/424596 · Cited by 327 · see citing works

Cutting Edge: Stat6-Dependent Substrate Depletion Regulates Nitric Oxide Production

Rutschman, R. L., Lang, R., Hesse, M., Ihle, J. N., Wynn, T. A., & Murray, P. J. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.4.2173 · Cited by 324 · see citing works

Nitric oxide and nitrosative stress tolerance in bacteria

Poole, R. K. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330176 · Cited by 269 · see citing works

Enhancer-Mediated Control of Macrophage-Specific Arginase I Expression

Pauleau, A., Rutschman, R. L., Lang, R., Pernis, A. B., Watowich, S. S., & Murray, P. J. (2004) · The Journal of Immunology · doi:10.4049/jimmunol.172.12.7565 · Cited by 243 · see citing works

Coinduction of Nitric-oxide Synthase and Arginase I in Cultured Rat Peritoneal Macrophages and Rat Tissues in Vivo by Lipopolysaccharide

Sonoki, T., Nagasaki, A., Gotoh, T., Takiguchi, M., Takeya, M., Matsuzaki, H., & Mori, M. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.6.3689 · Cited by 217 · see citing works

Induction of arginase I transcription by IL-4 requires a composite DNA response element for STAT6 and C/EBPβ

Gray, M. J., Poljakovic, M., Kepka-Lenhart, D., & Morris, S. M. (2005) · Gene · doi:10.1016/j.gene.2005.04.004 · Cited by 191 · see citing works

Crystal structure of human arginase I at 1.29-Å resolution and exploration of inhibition in the immune response

Costanzo, L. D., Sabio, G., Mora, A., Rodrı́guez, P. C., Ochoa, A. C., Centeno, F., & Christianson, D. W. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504027102 · Cited by 190 · see citing works

Translational Control of Inducible Nitric Oxide Synthase by IL-13 and Arginine Availability in Inflammatory Macrophages

El-Gayar, S., Thüring, H., Pfeilschifter, J. M., Röllinghoff, M., & Bogdan, C. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.171.9.4561 · Cited by 180 · see citing works

L-arginine metabolism and its impact on host immunity against Leishmania infection

Wanasen, N., & Soong, L. (2007) · Immunologic Research · doi:10.1007/s12026-007-8012-y · Cited by 178 · see citing works

Helicobacter pylori Induces Macrophage Apoptosis by Activation of Arginase II

Gobert, A. P., Cheng, Y., Wang, J., Boucher, J., Iyer, R. K., Cederbaum, S. D., Casero, R. A., Newton, J. C., & Wilson, K. T. (2002) · The Journal of Immunology · doi:10.4049/jimmunol.168.9.4692 · Cited by 173 · see citing works

Mouse Model for Human Arginase Deficiency

Iyer, R. K., Yoo, P. K., Kern, R. M., Rozengurt, N., Tsoa, R. W., O’Brien, W. E., Yu, H., Grody, W. W., & Cederbaum, S. D. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.13.4491-4498.2002 · Cited by 171 · see citing works

Analysis of Nitric Oxide Synthase and Nitrotyrosine Expression in Human Pulmonary Tuberculosis

Choi, H.-S., Rai, P. R., Chu, H. W., Cool, C. D., & Chan, E. D. (2002) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2201023 · Cited by 161 · see citing works

Re-examination of the Role of Suppressor of Cytokine Signaling 1 (SOCS1) in the Regulation of Toll-like Receptor Signaling

Gingras, S., Parganas, E., Pauw, A. D., Ihle, J. N., & Murray, P. J. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m411043200 · Cited by 148 · see citing works

Spermine Causes Loss of Innate Immune Response to Helicobacter pylori by Inhibition of Inducible Nitric-oxide Synthase Translation

Bussière, F. I., Chaturvedi, R., Cheng, Y., Gobert, A. P., Asim, M., Blumberg, D. R., Xu, H., Kim, P. Y., Hacker, A., Casero, R. A., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.c400498200 · Cited by 144 · see citing works

Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control ofMycobacterium tuberculosisin the Murine Lung

Cooper, A. M., Pearl, J. E., Brooks, J. V., Ehlers, S., & Orme, I. M. (2000) · Infection and Immunity · doi:10.1128/iai.68.12.6879-6882.2000 · Cited by 133 · see citing works

Mechanism of Inducible Nitric Oxide Synthase Exclusion from Mycobacterial Phagosomes

Davis, A. S., Vergne, I., Master, S. S., Kyei, G. B., Chua, J., & Deretic, V. P. (2007) · PLoS Pathogens · doi:10.1371/journal.ppat.0030186 · Cited by 114 · see citing works

An Effect of Parasite-Encoded Arginase on the Outcome of Murine Cutaneous Leishmaniasis

Dixit, U. G., Roberts, S. C., Dalvi, R. P., Corraliza, I., Ullman, B., & Wilson, M. E. (2007) · The Journal of Immunology · doi:10.4049/jimmunol.179.12.8446 · Cited by 113 · see citing works

Chlamydial Infection in Inducible Nitric Oxide Synthase Knockout Mice

Igietseme, J. U., Perry, L. L., Ananaba, G. A., Uriri, I. M., Ojior, O. O., Kumar, S. N., & Caldwell, H. D. (1998) · Infection and Immunity · doi:10.1128/iai.66.4.1282-1286.1998 · Cited by 98 · see citing works

Inhibition of Inducible Nitric Oxide Synthase Exacerbates Chronic Cerebral Toxoplasmosis in Toxoplasma gondii-Susceptible C57BL/6 Mice But Does Not Reactivate the Latent Disease in T. gondii-Resistant BALB/c Mice

Schlüter, D., Deckert‐Schlüter, M., Lorenz, E., Meyer, T., Röllinghoff, M., & Bogdan, C. (1999) · The Journal of Immunology · doi:10.4049/jimmunol.162.6.3512 · Cited by 96 · see citing works

Decreased Expression of CD3ζ and Nuclear Transcription Factor κB in Patients with Pulmonary Tuberculosis: Potential Mechanisms and Reversibility with Treatment

Zea, A. H., Culotta, K. S., Ali, J., Mason, C. M., Park, H., Zabaleta, J., García, L. F., & Ochoa, A. C. (2006) · The Journal of Infectious Diseases · doi:10.1086/508200 · Cited by 72 · see citing works

An Inducible Enhancer Required forIl12bPromoter Activity in an Insulated Chromatin Environment

Zhou, L., Nazarian, A. A., Xu, J., Tantin, D. R., Corcoran, L. M., & Smale, S. T. (2007) · Molecular and Cellular Biology · doi:10.1128/mcb.00788-06 · Cited by 48 · see citing works

MACROPHAGE ARGINASE REGULATION BY CCAAT/ENHANCER-BINDING PROTEIN ??

Albina, J. E., Mahoney, E. J., Daley, J. M., Szollosi, D. E., Morris, S. M., & Reichner, J. S. (2005) · Shock · doi:10.1097/01.shk.0000148054.74268.e2 · Cited by 44 · see citing works

Arginine Homeostasis in J774.1 Macrophages in the Context of Mycobacterium bovis BCG Infection

Talaue, M. T., Venketaraman, V., Hazbón, M. H., Peteroy-Kelly, M. A., Seth, A., Colangeli, R., Alland, D., & Connell, N. D. (2006) · Journal of Bacteriology · doi:10.1128/jb.01687-05 · Cited by 39 · see citing works

MyD88-dependent changes in the pulmonary transcriptome after infection with<i>Chlamydia pneumoniae</i>

Rodríguez, N., Mages, J., Dietrich, H., Wantia, N., Wagner, H., Lang, R., & Miethke, T. (2007) · Physiological Genomics · doi:10.1152/physiolgenomics.00011.2007 · Cited by 37 · see citing works

Nitric oxide exerts distinct effects in local and systemic infections with Streptococcus pneumoniae

Kerr, A. R., Wei, X., Andrew, P. W., & Mitchell, T. J. (2004) · Microbial Pathogenesis · doi:10.1016/j.micpath.2004.02.001 · Cited by 33 · see citing works

Stimulation of peritoneal cell arginase by bacterial lipopolysaccharides.

Ryan, J. L., Yohe, W. B., & Morrison, D. C. (1980) · PubMed · Cited by 30 · see citing works

Macrophage activation and polarization: nomenclature and experimental guidelines

Murray, P. J., Allen, J. E., Biswas, S. K., Fisher, E. A., Gilroy, D. W., Goerdt, S., Gordon, S., Hamilton, J. A., Ivashkiv, L. B., Lawrence, T., et al. (2014) · Immunity · doi:10.1016/j.immuni.2014.06.008 · Cited by 6,337 · see citing works

Protective and pathogenic functions of macrophage subsets

Murray, P. J., & Wynn, T. A. (2011) · Nature Reviews Immunology · doi:10.1038/nri3073 · Cited by 5,269 · see citing works

Alternative activation of macrophages: mechanism and functions

Gordon, S., & Martinez, F. O. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.007 · Cited by 4,197 · see citing works

Macrophage Polarization

Murray, P. J. (2017) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022516-034339 · Cited by 2,981 · see citing works

Transcriptional regulation of macrophage polarization: enabling diversity with identity

Lawrence, T., & Natoli, G. (2011) · Nature Reviews Immunology · doi:10.1038/nri3088 · Cited by 2,284 · see citing works

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

Wang, R., Dillon, C. P., Shi, L. Z., Milasta, S., Carter, R., Finkelstein, D., McCormick, L. L., Fitzgerald, P., Chi, H., Munger, J., et al. (2011) · Immunity · doi:10.1016/j.immuni.2011.09.021 · Cited by 2,140 · see citing works

Microglial <scp>M1/M2</scp> polarization and metabolic states

Orihuela, R., McPherson, C. A., & Harry, G. J. (2016) · British Journal of Pharmacology · doi:10.1111/bph.13139 · Cited by 2,070 · see citing works

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

Kelly, B., & O'Neill, L. A. (2015) · Cell Research · doi:10.1038/cr.2015.68 · Cited by 1,876 · see citing works

Macrophages: master regulators of inflammation and fibrosis

Wynn, T., & Barron, L. (2010) · Seminars in Liver Disease · doi:10.1055/s-0030-1255354 · Cited by 1,392 · see citing works

Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

Rath, M., ller, I. M. ⁄., Kropf, P., Closs, E. I., & Munder, M. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00532 · Cited by 1,271 · see citing works

M1 and M2 Macrophages: Oracles of Health and Disease

Mills, C. D. (2012) · Critical Reviews in Immunology · doi:10.1615/critrevimmunol.v32.i6.10 · Cited by 1,145 · see citing works

Macrophage defense mechanisms against intracellular bacteria

Weiss, G., & Schaible, U. E. (2015) · Immunological Reviews · doi:10.1111/imr.12266 · Cited by 989 · see citing works

Novel Markers to Delineate Murine M1 and M2 Macrophages

Jablonski, K., Amici, S. A., Webb, L., Ruiz‐Rosado, J. D. D., Popovich, P. G., Partida‐Sánchez, S., & Guerau‐de‐Arellano, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0145342 · Cited by 1,003 · see citing works

Nitric oxide synthase in innate and adaptive immunity: an update

Bogdan, C. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.01.003 · Cited by 862 · see citing works

Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor

Marigo, I., Bosio, E., Solito, S., Mesa, C., Fernández, A., Dolcetti, L., Ugel, S., Sonda, N., Bicciato, S., Falisi, E., et al. (2010) · Immunity · doi:10.1016/j.immuni.2010.05.010 · Cited by 854 · see citing works

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

Pesce, J. T., Ramalingam, T. R., Mentink-Kane, M. M., Wilson, M. S., El Kasmi, K. C., Smith, A. M., Thompson, R. W., Cheever, A. W., Murray, P. J., & Wynn, T. A. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000371 · Cited by 816 · see citing works

Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease

Dyken, S. J. V., & Locksley, R. M. (2013) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032712-095906 · Cited by 714 · see citing works

Macrophage polarization in pathology

Sica, A., Erreni, M., Allavena, P., & Porta, C. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-1995-y · Cited by 673 · see citing works

Arginase: an emerging key player in the mammalian immune system

Munder, M. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00291.x · Cited by 701 · see citing works

Macrophages and cancer: from mechanisms to therapeutic implications

Ostuni, R., Kratochvill, F., Murray, P. J., & Natoli, G. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.02.004 · Cited by 685 · see citing works

Type 2 cytokines: mechanisms and therapeutic strategies

Wynn, T. A. (2015) · Nature reviews. Immunology · doi:10.1038/nri3831 · Cited by 671 · see citing works

Macrophage phenotypes in atherosclerosis

Colin, S., Chinetti‐Gbaguidi, G., & Staels, B. (2014) · Immunological Reviews · doi:10.1111/imr.12218 · Cited by 657 · see citing works

Differential activation and antagonistic function of HIF-α isoforms in macrophages are essential for NO homeostasisPreprint

Takeda, N., O'Dea, E. L., Doedens, A. L., Kim, J., Weidemann, A., Stockmann, C., Asagiri, M., Simon, M. C., Hoffmann, A., & Johnson, R. S. (2010) · Genes & Development · doi:10.1101/gad.1881410 · Cited by 621 · see citing works

Modulation of innate immunity by Toxoplasma gondii virulence effectors

Hunter, C. A., & Sibley, L. D. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2858 · Cited by 570 · see citing works

Obstacles and opportunities for understanding macrophage polarization

Murray, P. J., & Wynn, T. A. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.0710409 · Cited by 558 · see citing works

Macrophage-Mediated Inflammation in Normal and Diabetic Wound Healing

Boniakowski, A. E., Kimball, A., Jacobs, B. N., Kunkel, S. L., & Gallagher, K. A. (2017) · The Journal of Immunology · doi:10.4049/jimmunol.1700223 · Cited by 546 · see citing works

Macrophage plasticity in experimental atherosclerosis

Khallou-Laschet, J., Varthaman, A., Fornasa, G., Compain, C., Gaston, A.-T., Clement, M., Dussiot, M., Levillain, O., Graff-Dubois, S., Nicoletti, A., et al. (2010) · PLoS ONE · doi:10.1371/journal.pone.0008852 · Cited by 517 · see citing works

Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment

Steggerda, S. M., Bennett, M. K., Chen, J., Emberley, E. D., Huang, T. C., Janes, J. R., Li, W., MacKinnon, A. L., Makkouk, A., Marguier, G. M., et al. (2017) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-017-0308-4 · Cited by 488 · see citing works

Recent advances in arginine metabolism: roles and regulation of the arginases

Morris Jr, S. M. (2009) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2009.00278.x · Cited by 485 · see citing works

Innate immunity to Toxoplasma gondii infection

Yarovinsky, F. (2014) · Nature reviews. Immunology · doi:10.1038/nri3598 · Cited by 462 · see citing works

New Insights on the Role of Lipid Metabolism in the Metabolic Reprogramming of Macrophages

Batista‐González, A., Vidal, R. M., Criollo, A., & Carreño, L. J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.02993 · Cited by 435 · see citing works

Myeloid Cell-Derived Arginase in Cancer Immune Response

Grzywa, T. M., Sosnowska, A., Matryba, P., Rydzyńska, Z., Jasiński, M., Nowis, D., & Gołąb, J. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.00938 · Cited by 434 · see citing works

Tumour-associated macrophages-derived CXCL8 determines immune evasion through autonomous PD-L1 expression in gastric cancer

Lin, C., He, H., Liu, H., Li, R., Chen, Y., Qi, Y., Jiang, Q., Chen, L., Zhang, P., Zhang, H., et al. (2019) · Gut · doi:10.1136/gutjnl-2018-316324 · Cited by 420 · see citing works

Macrophages and control of granulomatous inflammation in tuberculosis

Flynn, J. L., Chan, J., & Lin, P. L. (2011) · Mucosal Immunology · doi:10.1038/mi.2011.14 · Cited by 415 · see citing works

RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming

Yin, H., Zhang, X., Yang, P., Zhang, X., Peng, Y., Li, D., Yu, Y., Wu, Y., Wang, Y., Zhang, J., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21514-8 · Cited by 410 · see citing works

Adenosine promotes alternative macrophage activation via A2A and A2B receptors

Csóka, B., Selmeczy, Z., Koscsó, B., Németh, Z. H., Pacher, P., Murray, P. J., Kepka‐Lenhart, D., Morris, S. M., Gause, W. C., Leibovich, S. J., et al. (2011) · The FASEB Journal · doi:10.1096/fj.11-190934 · Cited by 378 · see citing works

Arginine-dependent immune responses

Líndez, A.-A. M. I., & Reith, W. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03828-4 · Cited by 368 · see citing works

Regulation of inflammation by interleukin-4: a review of "alternatives"

Luzina, I. G., Keegan, A. D., Heller, N. M., Rook, G. A. W., Shea-Donohue, T., & Atamas, S. P. (2012) · Journal of Leukocyte Biology · doi:10.1189/jlb.0412214 · Cited by 351 · see citing works

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

Mattila, J. T., Ojo, O. O., Kepka‐Lenhart, D., Marino, S., Kim, J. H., Eum, S. Y., Via, L. E., Barry, C. E., Klein, E. C., Kirschner, D. E., et al. (2013) · The Journal of Immunology · doi:10.4049/jimmunol.1300113 · Cited by 340 · see citing works

Alternatively activated macrophages derived from monocytes and tissue macrophages are phenotypically and functionally distinct

Gundra, U. M., Girgis, N. M., Ruckerl, D., Jenkins, S., Ward, L. N., Kurtz, Z. D., Wiens, K. E., Tang, M. S., Basu-Roy, U., Mansukhani, A., et al. (2014) · Blood · doi:10.1182/blood-2013-08-520619 · Cited by 371 · see citing works

Macrophage PI3Kγ Drives Pancreatic Ductal Adenocarcinoma Progression

Kaneda, M. M., Cappello, P., Nguyen, A. V., Ralainirina, N., Hardamon, C. R., Foubert, P., Schmid, M. C., Sun, P., Mose, E. S., Bouvet, M., et al. (2016) · Cancer Discovery · doi:10.1158/2159-8290.cd-15-1346 · Cited by 330 · see citing works

Metabolic origins of spatial organization in the tumor microenvironment

Carmona‐Fontaine, C., Déforet, M., Akkari, L., Thompson, C. B., Joyce, J. A., & Xavier, J. B. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1700600114 · Cited by 322 · see citing works

Metabolic orchestration of the wound healing response

Eming, S. A., Murray, P. J., & Pearce, E. J. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.07.017 · Cited by 319 · see citing works

Th1/Th2 Paradigm Extended: Macrophage Polarization as an Unappreciated Pathogen-Driven Escape Mechanism?

Muraille, É., Léo, O., & Moser, M. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00603 · Cited by 313 · see citing works

Control of immune response by amino acid metabolism

Grohmann, U., & Bronte, V. (2010) · Immunological Reviews · doi:10.1111/j.1600-065x.2010.00915.x · Cited by 311 · see citing works

Microbial manipulation of receptor crosstalk in innate immunity

Hajishengallis, G., & Lambris, J. D. (2011) · Nature reviews. Immunology · doi:10.1038/nri2918 · Cited by 307 · see citing works

Adrenergic Signaling in Muscularis Macrophages Limits Infection-Induced Neuronal Loss

Matheis, F., Muller, P. A., Graves, C. L., Gabanyi, I., Kerner, Z. J., Costa-Borges, D., Ahrends, T., Rosenstiel, P. C., & Mucida, D. (2020) · Cell · doi:10.1016/j.cell.2019.12.002 · Cited by 303 · see citing works

Tet2 restrains inflammatory gene expression in macrophages

Cull, A. H., Snetsinger, B., Buckstein, R., Wells, R. A., & Rauh, M. J. (2017) · Experimental Hematology · doi:10.1016/j.exphem.2017.08.001 · Cited by 295 · see citing works

Functions of arginase isoforms in macrophage inflammatory responses: impact on cardiovascular diseases and metabolic disorders

Yang, Z., & Ming, X.-F. (2014) · Frontiers in Immunology · doi:10.3389/fimmu.2014.00533 · Cited by 290 · see citing works

Alternatively activated macrophages in infection and autoimmunity

Fairweather, D., & Cihakova, D. (2009) · Journal of Autoimmunity · doi:10.1016/j.jaut.2009.09.012 · Cited by 290 · see citing works

TSC1 controls macrophage polarization to prevent inflammatory disease

Zhu, L., Yang, T., Li, L., Sun, L., Hou, Y., Hu, X., Zhang, L., Tian, H., Zhao, Q., Peng, J., et al. (2014) · Nature Communications · doi:10.1038/ncomms5696 · Cited by 285 · see citing works

Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis

Takeda, Y., Costa, S., Delamarre, E., Roncal, C., de Oliveira, R. L., Squadrito, M. L., Finisguerra, V., Deschoemaeker, S., Bruyére, F., Wenes, M., et al. (2011) · Nature · doi:10.1038/nature10507 · Cited by 287 · see citing works

Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

Rodrı́guez, P. C., Ochoa, A. C., & Al-Khami, A. A. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00093 · Cited by 287 · see citing works

Toxoplasma gondii Rhoptry Kinase ROP16 Activates STAT3 and STAT6 Resulting in Cytokine Inhibition and Arginase-1-Dependent Growth Control

Butcher, B. A., Fox, B. A., Rommereim, L. M., Kim, S. G., Maurer, K. J., Yarovinsky, F., Herbert, D. R., Bzik, D. J., & Denkers, E. (2011) · PLoS Pathogens · doi:10.1371/journal.ppat.1002236 · Cited by 282 · see citing works

Effect of helminth-induced immunity on infections with microbial pathogens

Salgame, P., Yap, G. S., & Gause, W. C. (2013) · Nature Immunology · doi:10.1038/ni.2736 · Cited by 281 · see citing works

TNF Counterbalances the Emergence of M2 Tumor Macrophages

Kratochvill, F., Neale, G. A. M., Haverkamp, J. M., de Velde, L.-A. V., Smith, A. M., Kawauchi, D., McEvoy, J. D., Roussel, M. F., Dyer, M. A., Qualls, J. E., et al. (2015) · Cell Reports · doi:10.1016/j.celrep.2015.08.033 · Cited by 278 · see citing works

Contribution of metabolic reprogramming to macrophage plasticity and function

Kasmi, K. C. E., & Stenmark, K. R. (2015) · Seminars in Immunology · doi:10.1016/j.smim.2015.09.001 · Cited by 276 · see citing works

Inflammatory monocytes regulate pathologic responses to commensals during acute gastrointestinal infection

Grainger, J. R., Wohlfert, E. A., Fuss, I. J., Bouladoux, N. J., Askenase, M. H., Legrand, F., Koo, L. Y., Brenchley, J. M., Fraser, I. D. C., & Belkaid, Y. (2013) · Nature Medicine · doi:10.1038/nm.3189 · Cited by 259 · see citing works

Host protective roles of type 2 immunity: Parasite killing and tissue repair, flip sides of the same coin

Allen, J. E., & Sutherland, T. E. (2014) · Seminars in Immunology · doi:10.1016/j.smim.2014.06.003 · Cited by 260 · see citing works

Division of labor between lung dendritic cells and macrophages in the defense against pulmonary infections

Guilliams, M., Lambrecht, B. N., & Hammad, H. (2013) · Mucosal Immunology · doi:10.1038/mi.2013.14 · Cited by 261 · see citing works

Adventitial Fibroblasts Induce a Distinct Proinflammatory/Profibrotic Macrophage Phenotype in Pulmonary Hypertension

Kasmi, K. C. E., Pugliese, S. C., Riddle, S. R., Poth, J. M., Anderson, A. L., Frid, M. G., Li, M., Pullamsetti, S. S., Savai, R., Nagel, M. A., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1303048 · Cited by 247 · see citing works

Amino acid auxotrophy as a system of immunological control nodes

Murray, P. J. (2016) · Nature Immunology · doi:10.1038/ni.3323 · Cited by 248 · see citing works

Modulation of the Arginase Pathway in the Context of Microbial Pathogenesis: A Metabolic Enzyme Moonlighting as an Immune Modulator

Das, P., Lahiri, A., Lahiri, A., & Chakravortty, D. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1000899 · Cited by 247 · see citing works

Local Arginase 1 Activity Is Required for Cutaneous Wound Healing

Campbell, L., Saville, C. R., Murray, P. J., Cruickshank, S. M., & Hardman, M. J. (2013) · Journal of Investigative Dermatology · doi:10.1038/jid.2013.164 · Cited by 246 · see citing works

Toxoplasma Polymorphic Effectors Determine Macrophage Polarization and Intestinal Inflammation

Jensen, K. D. C., Wang, Y., Wojno, E. D. T., Shastri, A. J., Hu, K. H., Cornel, L., Boedec, E., Ong, Y.-C., Chien, Y., Hunter, C. A., et al. (2011) · Cell Host & Microbe · doi:10.1016/j.chom.2011.04.015 · Cited by 236 · see citing works

Single cell RNA sequencing identifies unique inflammatory airspace macrophage subsets

Mould, K. J., Jackson, N. D., Henson, P. M., Seibold, M. A., & Janssen, W. J. (2019) · JCI Insight · doi:10.1172/jci.insight.126556 · Cited by 236 · see citing works

More than just protein building blocks: how amino acids and related metabolic pathways fuel macrophage polarization

Kieler, M., Hofmann, M., & Schabbauer, G. (2021) · FEBS Journal · doi:10.1111/febs.15715 · Cited by 246 · see citing works

The Roles of Hypoxia Signaling in the Pathogenesis of Cardiovascular Diseases

Abe, H., Semba, H., & Takeda, N. (2017) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.rv17009 · Cited by 237 · see citing works

Advanced Age Impairs Macrophage Polarization

Mahbub, S., Deburghgraeve, C. R., & Kovacs, E. J. (2012) · Journal of Interferon &amp; Cytokine Research · doi:10.1089/jir.2011.0058 · Cited by 222 · see citing works

Suppressor of cytokine signaling (SOCS)1 is a key determinant of differential macrophage activation and function

Whyte, C. S., Bishop, E., Rückerl, D., Gaspar-Pereira, S., Barker, R. N., Allen, J. E., Rees, A. J., & Wilson, H. M. (2011) · Journal of Leukocyte Biology · doi:10.1189/jlb.1110644 · Cited by 216 · see citing works

Phytosterols Promote Liver Injury and Kupffer Cell Activation in Parenteral Nutrition–Associated Liver Disease

Kasmi, K. E., Anderson, A. L., Devereaux, M., Vue, P. M., Zhang, W.-J., Setchell, K., Karpen, S., & Sokol, R. (2013) · Science Translational Medicine · doi:10.1126/scitranslmed.3006898 · Cited by 201 · see citing works

Activation of Murine Macrophages

Mosser, D. M., & Zhang, X. (2008) · Current Protocols in Immunology · doi:10.1002/0471142735.im1402s83 · Cited by 211 · see citing works

Preexisting helminth infection induces inhibition of innate pulmonary anti-tuberculosis defense by engaging the IL-4 receptor pathway

Potian, J. A., Rafi, W., Bhatt, K., McBride, A., Gause, W. C., & Salgame, P. R. (2011) · The Journal of Experimental Medicine · doi:10.1084/jem.20091473 · Cited by 214 · see citing works

Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2

Huber, S., Hoffmann, R. F. G., Muskens, F., & Voehringer, D. (2010) · Blood · doi:10.1182/blood-2010-02-271981 · Cited by 207 · see citing works

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells

Marigo, I., Zilio, S., Desantis, G., Mlecnik, B., Agnellini, A. H. R., Ugel, S., Sasso, M. S., Qualls, J. E., Kratochvill, F., Zanovello, P., et al. (2016) · Cancer Cell · doi:10.1016/j.ccell.2016.08.004 · Cited by 204 · see citing works

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4-, and IFN-β-dependent

Shirey, K. A., Pletneva, L. M., Puche, A. C., Keegan, A. D., Prince, G. A., Blanco, J. C. G., & Vogel, S. N. (2010) · Mucosal Immunology · doi:10.1038/mi.2010.6 · Cited by 203 · see citing works

Macrophage Polarization Drives Granuloma Outcome during Mycobacterium tuberculosis Infection

Marino, S., Cilfone, N. A., Mattila, J. T., Linderman, J. J., Flynn, J. L., & Kirschner, D. E. (2014) · Infection and Immunity · doi:10.1128/iai.02494-14 · Cited by 193 · see citing works

Image based Machine Learning for identification of macrophage subsets

Rostam, H. M., Reynolds, P. M., Alexander, M. R., Gadegaard, N., & Ghaemmaghami, A. M. (2017) · Scientific Reports · doi:10.1038/s41598-017-03780-z · Cited by 196 · see citing works

TLR9-Targeted STAT3 Silencing Abrogates Immunosuppressive Activity of Myeloid-Derived Suppressor Cells from Prostate Cancer Patients

Hossain, D. M. S., Pal, S. K., Moreira, D., Duttagupta, P. A., Zhang, Q., Won, H., Jones, J. O., D’Apuzzo, M., Forman, S. J., & Kortylewski, M. (2015) · Clinical Cancer Research · doi:10.1158/1078-0432.ccr-14-3145 · Cited by 189 · see citing works

Metformin-treated cancer cells modulate macrophage polarization through AMPK-NF-κB signaling

Chiang, C., Chao, T., Su, Y., Hsu, C., Chien, C., Chiu, K., Shiah, S., Lee, C.-H., Liu, S.-Y., & Shieh, Y. (2017) · Oncotarget · doi:10.18632/oncotarget.14982 · Cited by 188 · see citing works

“Pumping iron”—how macrophages handle iron at the systemic, microenvironmental, and cellular levels

Nairz, M., Theurl, I., Swirski, F. K., & Weiss, G. (2017) · Pflügers Archiv - European Journal of Physiology · doi:10.1007/s00424-017-1944-8 · Cited by 178 · see citing works

Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPARγ and TR4 for Survival

Mahajan, S., Dkhar, H. K., Chandra, V., Dave, S., Nanduri, R., Janmeja, A. K., Agrewala, J. N., & Gupta, P. K. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103038 · Cited by 185 · see citing works

Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

Qualls, J. E., Subramanian, C., Rafi, W., Smith, A. M., Balouzian, L., DeFreitas, A. A., Shirey, K. A., Reutterer, B., Kernbauer, E., Stockinger, S., et al. (2012) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2012.07.012 · Cited by 184 · see citing works

Macrophage activation governs schistosomiasis‐induced inflammation and fibrosis

Barron, L., & Wynn, T. A. (2011) · European Journal of Immunology · doi:10.1002/eji.201141869 · Cited by 183 · see citing works

Traumatic brain injury induces macrophage subsets in the brain

Hsieh, C. L., Kim, C. C., Ryba, B. E., Niemi, E. C., Bando, J. K., Locksley, R. M., Liu, J., Nakamura, M. C., & Seaman, W. E. (2013) · European Journal of Immunology · doi:10.1002/eji.201243084 · Cited by 179 · see citing works

Chemotherapy-Induced IL34 Enhances Immunosuppression by Tumor-Associated Macrophages and Mediates Survival of Chemoresistant Lung Cancer Cells

Baghdadi, M., Wada, H., Nakanishi, S., Abe, H., Han, N., Putra, W. E., Endo, D., Watari, H., Sakuragi, N., Hida, Y., et al. (2016) · Cancer Research · doi:10.1158/0008-5472.can-16-1170 · Cited by 183 · see citing works

The role of polyamines in the regulation of macrophage polarization and function

Latour, Y. L., Gobert, A. P., & Wilson, K. T. (2019) · Amino Acids · doi:10.1007/s00726-019-02719-0 · Cited by 182 · see citing works

Identification and distribution of developing innate lymphoid cells in the fetal mouse intestine

Bando, J. K., Liang, H.-E., & Locksley, R. M. (2014) · Nature Immunology · doi:10.1038/ni.3057 · Cited by 179 · see citing works

Arginase 1 is a key driver of immune suppression in pancreatic cancer

Menjivar, R. E., Nwosu, Z. C., Du, W., Donahue, K. L., Hong, H. S., Espinoza, C. E., Brown, K. L., Velez-Delgado, A., Yan, W., Lima, F., et al. (2023) · eLife · doi:10.7554/elife.80721 · Cited by 180 · see citing works

Classical versus alternative macrophage activation: the Ying and the Yang in host defense against pulmonary fungal infections

Wager, C. M. L., & Wormley, F. L. (2014) · Mucosal Immunology · doi:10.1038/mi.2014.65 · Cited by 169 · see citing works

Biphasic Dynamics of Macrophage Immunometabolism during Mycobacterium tuberculosis Infection

Shi, L., Jiang, Q., Bushkin, Y., Subbian, S., & Tyagi, S. (2019) · mBio · doi:10.1128/mbio.02550-18 · Cited by 169 · see citing works

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

Qualls, J. E., Neale, G. A. M., Smith, A. M., Koo, M.-S., DeFreitas, A. A., Zhang, H., Kaplan, G., Watowich, S. S., & Murray, P. J. (2010) · Science Signaling · doi:10.1126/scisignal.2000955 · Cited by 167 · see citing works

Dichloroacetate improves immune dysfunction caused by tumor‐secreted lactic acid and increases antitumor immunoreactivity

Ohashi, T., Akazawa, T., Aoki, M., Kuze, B., Mizuta, K., Ito, Y., & Inoue, N. (2013) · International Journal of Cancer · doi:10.1002/ijc.28114 · Cited by 164 · see citing works

Lactate and IL6 define separable paths of inflammatory metabolic adaptation

Dichtl, S., Lindenthal, L., Zeitler, L., Behnke, K., Schlösser, D., Strobl, B., Scheller, J., Kasmi, K. C. E., & Murray, P. J. (2021) · Science Advances · doi:10.1126/sciadv.abg3505 · Cited by 163 · see citing works

Autocrine IL-10 Induces Hallmarks of Alternative Activation in Macrophages and Suppresses Antituberculosis Effector Mechanisms without Compromising T Cell Immunity

Schreiber, T., Ehlers, S., Heitmann, L., Rausch, A., Mages, J., Murray, P. J., Lang, R., & Hölscher, C. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803567 · Cited by 161 · see citing works

A critical role for suppressor of cytokine signalling 3 in promoting M 1 macrophage activation and function in vitro and in vivo

Arnold, C. E., Whyte, C. S., Gordon, P., Barker, R. N., Rees, A. J., & Wilson, H. M. (2013) · Immunology · doi:10.1111/imm.12173 · Cited by 157 · see citing works

Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

Sahin, E., Haubenwallner, S., Kuttke, M., Kollmann, I., Halfmann, A., Dohnal, A. M., Chen, L., Cheng, P. P., Hoesel, B., Einwallner, E., et al. (2014) · The Journal of Immunology · doi:10.4049/jimmunol.1302167 · Cited by 155 · see citing works

Arginine Metabolism in Bacterial Pathogenesis and Cancer Therapy

Xiong, L., Teng, J. L. L., Botelho, M. G., Lo, R. C., Lau, S. K. P., & Woo, P. C. Y. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17030363 · Cited by 152 · see citing works

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

Duque-Correa, M. A., Kühl, A. A., Rodriguez, P. C., Zedler, U., Schommer-Leitner, S., Rao, M., Weiner, J., Hurwitz, R., Qualls, J. E., Kosmiadi, G. A., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1408839111 · Cited by 146 · see citing works

The Role of Metabolic Remodeling in Macrophage Polarization and Its Effect on Skeletal Muscle Regeneration

Santa, F. D., Vitiello, L., Torcinaro, A., & Ferraro, E. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2017.7420 · Cited by 125 · see citing works

Arginine: Master and Commander in Innate Immune Responses

Morris, S. M. (2010) · Science Signaling · doi:10.1126/scisignal.3135pe27 · Cited by 96 · see citing works

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

Qualls, J. E., Neale, G. A. M., Smith, A. M., Koo, M.-S., DeFreitas, A. A., Zhang, H., Kaplan, G., Watowich, S. S., & Murray, P. J. (2010) · Science Signaling · doi:10.1126/scisignal.2000955 · Cited by 167 · see citing works

Arginase-1 expression in granulomas of tuberculosis patients: Figure 1

Pessanha, A. P., Martins, R. A. P., Mattos‐Guaraldi, A. L., Vianna, A. R. D. C. B., & Moreira, L. O. (2012) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2012.01012.x · Cited by 56 · see citing works

The absence of TNF permits myeloid Arginase 1 expression in experimental L. monocytogenes infection

Li, X., Lyons, A. B., Woods, G. M., & Körner, H. (2017) · Immunobiology · doi:10.1016/j.imbio.2017.05.012 · Cited by 10 · see citing works

Arginase-1 expression in granulomas of tuberculosis patients

Hor, S., Commun, T., Ca, I., On, T. I., Pessanha, A. P., Martins, R. A. P., Mattos-Guaraldi, A. L., Vianna, A. R. D. C. B., Moreira, L. O., Lilian, C., et al. (2012)