Microenvironmental regulation of tumor progression and metastasis

Quail, Daniela F, Joyce, Johanna A·2013·Nature Medicine

Cited by (154)

Items 101–154 of 154

  1. Chemotherapy and tumor microenvironment of pancreatic cancer
    Liu, Qiaofei, Liao, Quan, Zhao, Yupei · 2017 · Cancer Cell International
  2. Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
    Sethumadhavan, Shalini, Silva, Murillo, Philbrook, Phaethon, Nguyen, Thao, Hatfield, Stephen M., Ohta, Akio, Sitkovsky, Michail V. · 2017 · PLOS ONE
  3. A comprehensive review of SHP2 and its role in cancer
    Asmamaw, Moges Dessale, Shi, Xiao-Jing, Zhang, Li-Rong, Liu, Hong-Min · 2022 · Cellular Oncology
  4. Nanoparticle Interactions with the Tumor Microenvironment
    Huai, Yanyan, Hossen, Md Nazir, Wilhelm, Stefan, Bhattacharya, Resham, Mukherjee, Priyabrata · 2019 · Bioconjugate Chemistry
  5. The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond
    Sullivan, Ryan, Maresh, Grace, Zhang, Xin, Salomon, Carlos, Hooper, John, Margolin, David, Li, Li · 2017 · Frontiers in Endocrinology
  6. An organoid-based screen for epigenetic inhibitors that stimulate antigen presentation and potentiate T-cell-mediated cytotoxicity
    Zhou, Zhuolong, Van der Jeught, Kevin, Fang, Yuanzhang, Yu, Tao, Li, Yujing, Ao, Zheng, Liu, Sheng, Zhang, Lu, Yang, Yang, Eyvani, Haniyeh et al. · 2021 · Nature Biomedical Engineering
  7. Endothelial-to-mesenchymal transition (EndoMT): roles in tumorigenesis, metastatic extravasation and therapy resistance
    Platel, Valentin, Faure, Sébastien, Corre, Isabelle, Clere, Nicolas · 2019 · Journal of Oncology
  8. Exosomes as Emerging Pro-Tumorigenic Mediators of the Senescence-Associated Secretory Phenotype
    Jakhar, Rekha, Crasta, Karen · 2019 · International Journal of Molecular Sciences
  9. Nitric oxide mediates metabolic coupling of omentum-derived adipose stroma to ovarian and endometrial cancer cells
    Salimian Rizi, Bahar, Caneba, Christine, Nowicka, Aleksandra, Nabiyar, Ahmad W., Liu, Xinran, Chen, Kevin, Klopp, Ann, Nagrath, Deepak · 2015 · Cancer Research
  10. Exosomal PD‐L1: New Insights Into Tumor Immune Escape Mechanisms and Therapeutic Strategies
    Zhou, Kaijian, Guo, Shu, Li, Fei, Sun, Qiang, Liang, Guoxin · 2020 · Frontiers in Cell and Developmental Biology
  11. Drilling for Oil: Tumor-Surrounding Adipocytes Fueling Cancer
    Attané, Camille, Muller, Catherine · 2020 · Trends in Cancer
  12. Matrix stiffness‐mediated effects on macrophages polarization and their LOXL2 expression
    Xing, Xiaoxia, Wang, Yaohui, Zhang, Xi, Gao, Xiangyu, Li, Miao, Wu, Sifan, Zhao, Yan, Chen, Jie, Gao, Dongmei, Chen, Rongxin et al. · 2021 · The FEBS Journal
  13. Aurora A inhibition eliminates myeloid cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in breast cancer
    Yin, Tingting, Zhao, Zhi-Bin, Guo, Jing, Wang, Tianchen, Yang, Jing-Bo, Wang, Chao, Long, Jie, Ma, Shisong, Huang, Qiang, Zhang, Kaiguang et al. · 2019 · Cancer Research
  14. MMP14 in sarcoma: a regulator of tumor microenvironment communication in connective tissues
    Gonzalez-Molina, Jordi, Gramolelli, Silvia, Liao, Zehuan, Carlson, Joseph W., Ojala, Päivi M., Lehti, Kaisa · 2019 · Cells
  15. BRCA mutational status shapes the stromal microenvironment of pancreatic cancer linking clusterin expression in cancer associated fibroblasts with HSF1 signaling
    Shaashua, Lee, Ben-Shmuel, Aviad, Pevsner-Fischer, Meirav, Friedman, Gil, Levi-Galibov, Oshrat, Nandakumar, Subhiksha, Barki, Debra, Nevo, Reinat, Brown, Lauren E., Zhang, Wenhan et al. · 2022 · Nature Communications
  16. Lipocalin 2 from macrophages stimulated by tumor cell-derived sphingosine 1-phosphate promotes lymphangiogenesis and tumor metastasis
    Jung, Michaela, Ören, Bilge, Mora, Javier, Mertens, Christina, Dziumbla, Sarah, Popp, Rüdiger, Weigert, Andreas, Grossmann, Nina, Fleming, Ingrid, Brüne, Bernhard · 2016 · Science Signaling
  17. The current landscape of 3D in vitro tumor models: what cancer hallmarks are accessible for drug discovery?
    Rodenhizer, Darren, Dean, Teresa, D'Arcangelo, Elisa, McGuigan, Alison P. · 2018 · Advanced Healthcare Materials
  18. Patient-derived xenograft models of pancreatic cancer: overview and comparison with other types of models
    Garcia, Patrick L., Miller, Aubrey L., Yoon, Karina J. · 2020 · Cancers
  19. A novel antagonist of CXCR4 prevents bone marrow-derived mesenchymal stem cell-mediated osteosarcoma and hepatocellular carcinoma cell migration and invasion
    Fontanella, Raffaela, Pelagalli, Alessandra, Nardelli, Anna, D'Alterio, Crescenzo, Ieranò, Caterina, Cerchia, Laura, Lucarelli, Enrico, Scala, Stefania, Zannetti, Antonella · 2016 · Cancer Letters
  20. A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts
    Kabir, Tasnuva D., Leigh, Ross J., Tasena, Hataitip, Mellone, Massimiliano, Coletta, Ricardo D., Parkinson, Eric K., Prime, Stephen S., Thomas, Gareth J., Paterson, Ian C., Zhou, Donghui et al. · 2016 · Aging
  21. Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment
    Olsson, Anders, Nakhlé, Jessica, Sundstedt, Anette, Plas, Pascale, Bauchet, Anne-Laure, Pierron, Valérie, Bruetschy, Luce, Deronic, Adnan, Törngren, Marie, Liberg, David et al. · 2015 · Journal for ImmunoTherapy of Cancer
  22. Mechanisms and Strategies to Overcome Drug Resistance in Colorectal Cancer
    Haynes, Jennifer, Manogaran, Prasath · 2025 · International Journal of Molecular Sciences
  23. Interactions between cancer stem cells, immune system and some environmental components: Friends or foes?
    Vahidian, Fatemeh, Duijf, Pascal H.G., Safarzadeh, Elham, Derakhshani, Afshin, Baghbanzadeh, Amir, Baradaran, Behzad · 2019 · Immunology Letters
  24. 3D hydrogel-based microwell arrays as a tumor microenvironment model to study breast cancer growth
    Casey, John, Yue, Xiaoshan, Nguyen, Trung Dung, Acun, Aylin, Zellmer, Victoria R, Zhang, Siyuan, Zorlutuna, Pinar · 2017 · Biomedical Materials
  25. Investigation of PPIX-Lipo-MnO2 to enhance photodynamic therapy by improving tumor hypoxia
    Chudal, Lalit, Pandey, Nil Kanatha, Phan, Jonathan, Johnson, Omar, Li, Xiuying, Chen, Wei · 2019 · Materials Science and Engineering: C
  26. Recapitulating the vasculature using ORGAN-ON-CHIP technology
    Pollet, Andreas M.A.O., den Toonder, Jaap M.J. · 2020 · Bioengineering
  27. Modeling Tumor Microenvironment Complexity In Vitro: Spheroids as Physiologically Relevant Tumor Models and Strategies for Their Analysis
    Shah, Shrey, D’Souza, Gerard G. M. · 2025 · Cells
  28. Role of the tumor microenvironment in cancer hallmarks and targeted therapy (Review)
    Naser, Rayan, Fakhoury, Isabelle, El‑Fouani, Adam, Abi‑Habib, Ralph, El‑Sibai, Mirvat · 2022 · International Journal of Oncology
  29. Radiographical assessment of tumour stroma and treatment outcomes using deep learning: a retrospective, multicohort study
    Jiang, Yuming, Liang, Xiaokun, Han, Zhen, Wang, Wei, Xi, Sujuan, Li, Tuanjie, Chen, Chuanli, Yuan, Qingyu, Li, Na, Yu, Jiang et al. · 2021 · The Lancet Digital Health
  30. Activated hepatic stellate cells promote angiogenesis via interleukin-8 in hepatocellular carcinoma
    Zhu, Bing, Lin, Nan, Zhang, Min, Zhu, Yong, Cheng, Huanhuan, Chen, Shuxian, Ling, Yunbiao, Pan, Weidong, Xu, Ruiyun · 2015 · Journal of Translational Medicine
  31. Modular Hydrogel Vaccine for Programmable and Coordinate Elicitation of Cancer Immunotherapy
    Ji, Panpan, Sun, Wenqi, Zhang, Siyan, Xing, Yuqi, Wang, Chen, Wei, Mengying, Li, Qiuyun, Ji, Gang, Yang, Guodong · 2023 · Advanced Science
  32. Eukaryotic elongation factor-2 kinase (eEF2K) signaling in tumor and microenvironment as a novel molecular target
    Karakas, Didem, Ozpolat, Bulent · 2020 · Journal of Molecular Medicine
  33. Cytoneme-mediated signaling essential for tumorigenesis
    Fereres, Sol, Hatori, Ryo, Hatori, Makiko, Kornberg, Thomas B. · 2019 · PLOS Genetics
  34. Recapitulation of complex transport and action of drugs at the tumor microenvironment using tumor-microenvironment-on-chip
    Han, Bumsoo, Qu, Chunjing, Park, Kinam, Konieczny, Stephen F., Korc, Murray · 2016 · Cancer Letters
  35. Spage2vec: Unsupervised representation of localized spatial gene expression signatures
    Partel, Gabriele, Wählby, Carolina · 2021 · The FEBS Journal
  36. Omics Technologies Improving Breast Cancer Research and Diagnostics
    Orsini, Arianna, Diquigiovanni, Chiara, Bonora, Elena · 2023 · International Journal of Molecular Sciences
  37. Identification of MTHFD2 as a prognostic biomarker and ferroptosis regulator in triple-negative breast cancer
    Zhang, Hao, Zhu, Shuangli, Zhou, Haiting, Li, Rui, Xia, Xiaohui, Xiong, Huihua · 2023 · Frontiers in Oncology
  38. Programming of macrophages by UV-irradiated apoptotic cancer cells inhibits cancer progression and lung metastasis
    Kim, Yong-Bae, Ahn, Young-Ho, Jung, Ji-Hae, Lee, Ye-Ji, Lee, Jin-Hwa, Kang, Jihee Lee · 2019 · Cellular & Molecular Immunology
  39. Efferocytosis Creates a Tumor Microenvironment Supportive of Tumor Survival and Metastasis
    2015 · Cancer Cell & Microenvironment
  40. Harnessing Ferroptosis to Overcome Drug Resistance in Colorectal Cancer: Promising Therapeutic Approaches
    Cheng, Xiaofei, Zhao, Feng, Ke, Bingxin, Chen, Dong, Liu, Fanlong · 2023 · Cancers
  41. Fibroblast-induced switching to the mesenchymal-like phenotype and PI3K/mTOR signaling protects melanoma cells from BRAF inhibitors
    Seip, Kotryna, Fleten, Karianne G., Barkovskaya, Anna, Nygaard, Vigdis, Haugen, Mads H., Engesæter, Birgit Ø., Mælandsmo, Gunhild M., Prasmickaite, Lina · 2016 · Oncotarget
  42. Digital image analysis and machine learning-assisted prediction of neoadjuvant chemotherapy response in triple-negative breast cancer
    Fisher, Timothy B., Saini, Geetanjali, Rekha, T. S., Krishnamurthy, Jayashree, Bhattarai, Shristi, Callagy, Grace, Webber, Mark, Janssen, Emiel A. M., Kong, Jun, Aneja, Ritu · 2024 · Breast Cancer Research
  43. Importance and Considerations of Antibody Engineering in Antibody-Drug Conjugates Development from a Clinical Pharmacologist’s Perspective
    Lucas, Andrew T., Moody, Amber, Schorzman, Allison N., Zamboni, William C. · 2021 · Antibodies
  44. Iron imaging reveals tumor and metastasis macrophage hemosiderin deposits in breast cancer
    Leftin, Avigdor, Ben-Chetrit, Nir, Klemm, Florian, Joyce, Johanna A., Koutcher, Jason A. · 2017 · PLOS ONE
  45. New chimeric antigen receptor design for solid tumors
    Wang, Yuedi, Luo, Feifei, Yang, Jiao, Zhao, Chujun, Chu, Yiwei · 2017 · Frontiers in Immunology
  46. Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases
    Pellegata, Natalia S., Berriel Diaz, Mauricio, Rohm, Maria, Herzig, Stephan · 2022 · Cancer and Metastasis Reviews
  47. Deep learning in digital pathology for personalized treatment plans of cancer patients
    Wen, Zhuoyu, Wang, Shidan, Yang, Donghan M., Xie, Yang, Chen, Mingyi, Bishop, Justin, Xiao, Guanghua · 2023 · Seminars in Diagnostic Pathology
  48. Interaction study of cancer cells and fibroblasts on a spatially confined oxygen gradient microfluidic chip to investigate the tumor microenvironment
    Sun, Wei, Chen, Yuqing, Wang, Yuerong, Luo, Pei, Zhang, Min, Zhang, Hongyang, Hu, Ping · 2018 · The Analyst
  49. Proteomic Identification of a Gastric Tumor ECM Signature Associated With Cancer Progression
    Moreira, Ana M., Ferreira, Rui M., Carneiro, Patrícia, Figueiredo, Joana, Osório, Hugo, Barbosa, José, Preto, John, Pinto-do-Ó, Perpétua, Carneiro, Fátima, Seruca, Raquel · 2022 · Frontiers in Molecular Biosciences
  50. Tumor microenvironment determines response to a heat-activated thermosensitive liposome formulation of cisplatin in cervical carcinoma
    Dou, Yannan N., Chaudary, Naz, Chang, Martin C., Dunne, Michael, Huang, Huang, Jaffray, David A., Milosevic, Michael, Allen, Christine · 2017 · Journal of Controlled Release
  51. Multi-Modal Multi-Spectral Intravital Macroscopic Imaging of Signaling Dynamics in Real Time during Tumor–Immune Interactions
    Liu, Tracy W., Gammon, Seth T., Fuentes, David, Piwnica-Worms, David · 2021 · Cells
  52. <scp>Noncontrast</scp> Magnetic Resonance Radiomics and Multilayer Perceptron Network Classifier: An approach for Predicting Fibroblast Activation Protein Expression in Patients With Pancreatic Ductal Adenocarcinoma
    Meng, Yinghao, Zhang, Hao, Li, Qi, Xing, Pengyi, Liu, Fang, Cao, Kai, Fang, Xu, Li, Jing, Yu, Jieyu, Feng, Xiaochen et al. · 2021 · Journal of Magnetic Resonance Imaging
  53. Exploring and bypassing resistance to targeted therapies in colorectal cancer
    Favier, Solène, Xiong, Wei, Chalabi-Dchar, Mounira, Chettab, Kamel, Piercey, Oliver, Wu, Ting, Fenouil, Tanguy, Albaret, Marie-Alexandra, Jordheim, Lars Petter, Diaz, Jean-Jacques et al. · 2025 · Biomedicine &amp; Pharmacotherapy
  54. Spatiotemporal analysis of tumour-infiltrating immune cells in biliary carcinogenesis
    Charbel, Alphonse, Tavernar, Luca, Albrecht, Thomas, Brinkmann, Fritz, Verheij, Joanne, Roos, Eva, Vogel, Monika Nadja, Köhler, Bruno, Springfeld, Christoph, Brobeil, Alexander et al. · 2022 · British Journal of Cancer