Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 953

The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.

A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells

Lee, Ju-Seog, Heo, Jeonghoon, Libbrecht, Louis, Chu, In-Sun, Kaposi-Novak, Pal, Calvisi, Diego F, Mikaelyan, Arsen, Roberts, Lewis R, Demetris, Anthony J, Sun, Zongtang, Nevens, Frederik, Roskams, Tania, Thorgeirsson, Snorri S·2006·Nature Medicine
DOI 10.1038/nm1377
Open this paper in CoChat — free account

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1038/nm1377

Cites

2 of 2 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 2 references

Research works printed but not linked: 38

  1. Parkin, D.M., Bray, F., Ferlay, J. & Pisani, P. Estimating the world cancer burden: Globocan 2000. Int. J. Cancer 94, 153–156 (2001). · DOI · Paper page
  2. El Serag, H.B. & Mason, A.C. Rising incidence of hepatocellular carcinoma in the United States. N. Engl. J. Med. 340, 745–750 (1999). · DOI · Paper page
  3. Bruix, J., Boix, L., Sala, M. & Llovet, J.M. Focus on hepatocellular carcinoma. Cancer Cell 5, 215–219 (2004). · DOI · Paper page
  4. Llovet, J.M. et al. Natural history of untreated nonsurgical hepatocellular carcinoma: rationale for the design and evaluation of therapeutic trials. Hepatology 29, 62–67 (1999). · DOI · Paper page
  5. Hanahan, D. & Weinberg, R.A. The hallmarks of cancer. Cell 100, 57–70 (2000). · DOI · Paper page
  6. Alizadeh, A.A. et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403, 503–511 (2000). · DOI · Paper page
  7. Ross, D.T. et al. Systematic variation in gene expression patterns in human cancer cell lines. Nat. Genet. 24, 227–235 (2000). · DOI · Paper page
  8. Roskams, T.A., Libbrecht, L. & Desmet, V.J. Progenitor cells in diseased human liver. Semin. Liver Dis. 23, 385–396 (2003). · DOI · Paper page
  9. Lee, J.S. et al. Application of comparative functional genomics to identify best-fit mouse models to study human cancer. Nat. Genet. 36, 1306–1311 (2004). · DOI · Paper page
  10. Lee, J.S., Grisham, J.W. & Thorgeirsson, S.S. Comparative functional genomics for identifying models of human cancer. Carcinogenesis 26, 1013–1020 (2005). · DOI
  11. Petkov, P.M. et al. Gene expression pattern in hepatic stem/progenitor cells during rat fetal development using complementary DNA microarrays. Hepatology 39, 617–627 (2004). · DOI
  12. Dabeva, M.D. & Shafritz, D.A. Hepatic stem cells and liver repopulation. Semin. Liver Dis. 23, 349–362 (2003). · DOI
  13. Thorgeirsson, S.S. & Grisham, J.W. Overview of recent experimental studies on liver stem cells. Semin. Liver Dis. 23, 303–312 (2003). · DOI
  14. Lee, J.S. et al. Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling. Hepatology 40, 667–676 (2004). · DOI · Paper page
  15. Chambers, A.F. & Matrisian, L.M. Changing views of the role of matrix metalloproteinases in metastasis. J. Natl. Cancer Inst. 89, 1260–1270 (1997). · DOI · Paper page
  16. Andreasen, P.A., Egelund, R. & Petersen, H.H. The plasminogen activation system in tumor growth, invasion, and metastasis. Cell. Mol. Life Sci. 57, 25–40 (2000). · DOI · Paper page
  17. Chang, C. & Werb, Z. The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis. Trends Cell Biol. 11, S37–S43 (2001). · DOI · Paper page
  18. Jothy, S. CD44 and its partners in metastasis. Clin. Exp. Metastasis 20, 195–201 (2003). · DOI
  19. Yu, Y. et al. Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. Nat. Med. 10, 175–181 (2004). · DOI · Paper page
  20. Curto, M. & McClatchey, A.I. Ezrin.a metastatic detERMinant? Cancer Cell 5, 113–114 (2004). · DOI
  21. Martin, T.A., Harrison, G., Mansel, R.E. & Jiang, W.G. The role of the CD44/ezrin complex in cancer metastasis. Crit. Rev. Oncol. Hematol. 46, 165–186 (2003). · DOI
  22. Kondo, K. et al. Risk factors for early death after liver resection in patients with solitary hepatocellular carcinoma. J. Hepatobiliary Pancreat. Surg. 12, 399–404 (2005). · doi:10.1007/s00534-005-1009-9
  23. Gouillat, C., Manganas, D., Saguier, G., Duque-Campos, R. & Berard, P. Resection of hepatocellular carcinoma in cirrhotic patients: longterm results of a prospective study. J. Am. Coll. Surg. 189, 282–290 (1999). · doi:10.1016/s1072-7515(99)00142-8
  24. Lee, J.S. & Thorgeirsson, S.S. Genome-scale profiling of gene expression in hepatocellular carcinoma: classification, survival prediction, and identification of therapeutic targets. Gastroenterology 127, S51–S55 (2004). · DOI
  25. Kitano, H. Cancer robustness: tumour tactics. Nature 426, 125 (2003). · DOI
  26. Postic, C. & Magnuson, M.A. DNA excision in liver by an albumin-Cre transgene occurs progressively with age. Genesis 26, 149–150 (2000). · DOI · Paper page
  27. Pinkert, C.A., Ornitz, D.M., Brinster, R.L. & Palmiter, R.D. An albumin enhancer located 10 kb upstream functions along with its promoter to direct efficient, liver-specific expression in transgenic mice. Genes Dev. 1, 268–276 (1987). · DOI · Paper page
  28. Ferrando, A.A. et al. Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia. Cancer Cell 1, 75–87 (2002). · DOI · Paper page
  29. Sarraf, C. et al. Cell behavior in the acetylaminofluorene-treated regenerating rat liver. Light and electron microscopic observations. Am. J. Pathol. 145, 1114–1126 (1994).
  30. Eferl, R. et al. Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53. Cell 112, 181–192 (2003). · DOI · Paper page
  31. Hilberg, F., Aguzzi, A., Howells, N. & Wagner, E.F. c-jun is essential for normal mouse development and hepatogenesis. Nature 365, 179–181 (1993). · DOI · Paper page
  32. Logan, C.Y. & Nusse, R. The Wnt signaling pathway in development and disease. Annu. Rev. Cell Dev. Biol. 20, 781–810 (2004). · DOI · Paper page
  33. Lee, J.S. & Thorgeirsson, S.S. Genetic profiling of human hepatocellular carcinoma. Semin. Liver Dis. 25, 125–132 (2005). · DOI
  34. Robrechts, C. et al. Primary liver tumour of intermediate (hepatocyte-bile duct cell) phenotype: a progenitor cell tumour? Liver 18, 288–293 (1998). · DOI
  35. Libbrecht, L., Desmet, V., Van Damme, B. & Roskams, T. The immunohistochemical phenotype of dysplastic foci in human liver: correlation with putative progenitor cells. J. Hepatol. 33, 76–84 (2000). · DOI · Paper page
  36. Wu, P.C. et al. Classification of hepatocellular carcinoma according to hepatocellular and biliary differentiation markers. Clinical and biological implications. Am. J. Pathol. 149, 1167–1175 (1996).
  37. Uenishi, T. et al. Cytokeratin 19 expression in hepatocellular carcinoma predicts early postoperative recurrence. Cancer Sci. 94, 851–857 (2003). · DOI · Paper page
  38. Durnez, A. et al. The clinicopathological and prognostic relevance of cytokeratin 7 and 19 expression in hepatocellular carcinoma. Hepatology (in the press).

Cited by

Metadata

Authors
Lee, J.-S., Heo, J., Libbrecht, L., Chu, I.-S., Kaposi-Novak, P., Calvisi, D. F., Mikaelyan, A., Roberts, L. R., Demetris, A. J., Sun, Z., Nevens, F., Roskams, T., & Thorgeirsson, S. S.
Venue
Nature Medicine
Publisher
Springer Science and Business Media LLC
Published
2006-03-12
Volume
12
Issue
4
Pages
410-416
ISSN
  • 1078-8956 (ISSN-L)
  • 1546-170X
DOI
10.1038/nm1377
OpenAlex
W2124471593
Cited by
953
References
2
FWCI
31.90
Type
journal article
Language
en
Open access
closed
Licence
www.springer.com/tdm (tdm)

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.