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Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
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“…blockade in MS, as evidenced by the downregulation of miR-219 and miR-338, two microRNAs that facilitate oligodendrocyte maturation by suppressing transcriptional inhibitors like Hes5 and Sox6, thereby disrupting the gene expression control required for lineage progression [126,127].”
Metadata
- Authors
- John, G. R., Shankar, S. L., Shafit-Zagardo, B., Massimi, A., Lee, S. C., Raine, C. S., & Brosnan, C. F.
- Venue
- Nature Medicine
- Published
- 2002-09-23
- Volume
- 8
- Issue
- 10
- Pages
- 1115-1121
- ISSN
- 1078-8956 (ISSN-L)
- 1546-170X
- OpenAlex
- W2035098555
- Cited by
- 477
- References
- 33
- FWCI
- 15.89
- Type
- journal article
- Language
- en
- Open access
- closed
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