Nucleic acid memory
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Escherichia coli has a storage density of 10^19 bits of data per cubic centimeter.
“Escherichia coli has a storage density of 1019 bits of data per cubic centimeter [5].”
From DNA Data Storage. (2023) · cites this paper as [5]
DNA has outstanding features of long-term, high-density, and low maintenance cost for data storage.
“with outstanding features of long-term, high-density, and low maintain cost”
From Large-Scale de Novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities (2021) · cites this paper as Zhirnov et al., 2016
DNA is a viable and compelling alternative to traditional storage media and has the potential to solve the world crisis of digital data explosion.
“DNA is believed to be a viable and compelling alternative to traditional storage media and to be potential to solve the world crisis of digital data explosion”
From Large-Scale de Novo Oligonucleotide Synthesis for Whole-Genome Synthesis and Data Storage: Challenges and Opportunities (2021) · cites this paper as Zhirnov et al., 2016
Recent progress in nucleic acid synthesis and sequencing continues to reduce the cost of writing and reading DNA, foreshadowing future commercially competitive DNA-based information storage.
“Recent progress in nucleic acid synthesis and sequencing technologies continue to reduce the cost of writing and reading DNA, foreshadowing future commercially competitive DNA-based information storage1,3–5.”
From Random access DNA memory using Boolean search in an archival file storage system (2021) · cites this paper as [1]
DNA can be used for the storage of arbitrary digital information at densities far exceeding conventional data storage technologies such as flash and tape memory, at scales well beyond the capacity of the largest existing data centers.
“While DNA is the polymer selected by evolution for the storage and transmission of genetic information in biology, it can also be used for the storage of arbitrary digital information at densities far exceeding conventional data storage technologies such as flash and tape memory, at scales well beyond the capacity of the largest existing data centers1,2.”
From Random access DNA memory using Boolean search in an archival file storage system (2021) · cites this paper as [1]
While the file system supports theoretical storage densities orders of magnitude higher than archival file storage systems based on hard disk, magnetic tape, or similar archival media, silica encapsulation of DNA file sequences lowers overall data storage density compared with bare DNA memory.
“First, while our file system supports theoretical storage densities that are orders of magnitude higher than archival file storage systems based on hard disk, magnetic tape, or similar archival media1,40 commonly used today, silica encapsulation of DNA file sequences lowers overall data storage density compared with bare DNA memory (Supplementary Section 6).”
From Random access DNA memory using Boolean search in an archival file storage system (2021) · cites this paper as [1]
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Cites
Molecular Cloning: A Laboratory Manual
Sambrook, J., Fritsch, E., & Maniatis, T. (1989) · UCLA - Biblioteca de Ciencias de la Salud · Cited by 133,589 · see citing works
Molecular cloning: A laboratory manual
Deininger, P. L. (1990) · Analytical Biochemistry · doi:10.1016/0003-2697(90)90595-z · Cited by 84,684 · see citing works
Folding DNA to create nanoscale shapes and patterns
Rothemund, P. W. K. (2006) · Nature · doi:10.1038/nature04586 · Cited by 7,320 · see citing works
Cradle to cradle: remaking the way we make things
Braungart, M., & McDonough, W. F. (2002) · Choice Reviews Online · doi:10.5860/choice.40-0914 · Cited by 3,850 · see citing works
The potential and challenges of nanopore sequencing
Branton, D., Deamer, D. W., Marziali, A., Bayley, H., Benner, S. A., Butler, T. J., Ventra, M. D., Garaj, S., Hibbs, A. H., Huang, X. C., et al. (2008) · Nature Biotechnology · doi:10.1038/nbt.1495 · Cited by 2,534 · see citing works
A DNA-fuelled molecular machine made of DNA
Yurke, B., Turberfield, A. J., Mills, A. P., Simmel, F. C., & Neumann, J. L. (2000) · Nature · doi:10.1038/35020524 · Cited by 2,426 · see citing works
The complete genome sequence of a Neanderthal from the Altai Mountains
Prüfer, K., Racimo, F., Patterson, N., Jay, F., Sankararaman, S., Sawyer, S., Heinze, A., Renaud, G., Sudmant, P. H., de Filippo, C., et al. (2014) · Nature · doi:10.1038/nature12886 · Cited by 2,254 · see citing works
The World’s Technological Capacity to Store, Communicate, and Compute Information
Hilbert, M., & López, P. (2011) · Science · doi:10.1126/science.1200970 · Cited by 1,643 · see citing works
Next-Generation Digital Information Storage in DNA
Church, G. M., Gao, Y., & Kosuri, S. (2012) · Science · doi:10.1126/science.1226355 · Cited by 1,441 · see citing works
Self-citationTowards Practical, High-Capacity, Low-Maintenance Information Storage in Synthesized DNA
Goldman, N., Bertone, P., Chen, S., Dessimoz, C., LeProust, E. M., Sipos, B., & Birney, E. (2013) · Nature · doi:10.1038/nature11875 · Cited by 1,220 · see citing works
The Digital Universe in 2020: Big Data, Bigger Digital Shadows, and Biggest Growth in the Far East
Gantz, J., & Reinsel, D. (2012) · Cited by 1,146 · see citing works
Neural network computation with DNA strand displacement cascades
Qian, L., Winfree, E., & Bruck, J. (2011) · Nature · doi:10.1038/nature10262 · Cited by 1,079 · see citing works
Recalibrating equus evolution using the genome sequence of an early middle pleistocene horse
Orlando, L., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., et al. (2013) · Nature · doi:10.1038/nature12323 · Cited by 841 · see citing works
Robust Chemical Preservation of Digital Information on DNA in Silica with Error-Correcting Codes
Grass, R. N., Heckel, R., Puddu, M., Paunescu, D., & Stark, W. J. (2015) · Angewandte Chemie International Edition · doi:10.1002/anie.201411378 · Cited by 754 · see citing works
DNA rendering of polyhedral meshes at the nanoscale
Benson, E., Mohammed, A., Gardell, J., Masich, S., Czeizler, E., Orponen, P., & Högberg, B. (2015) · Nature · doi:10.1038/nature14586 · Cited by 672 · see citing works
The half-life of DNA in bone: measuring decay kinetics in 158 dated fossils
Allentoft, M. E., Collins, M., Harker, D., Haile, J., Oskam, C. L., Hale, M. L., Campos, P. F., Samaniego, J. A., Gilbert, M. T. P., Willerslev, E., et al. (2012) · Proceedings of the Royal Society B: Biological Sciences · doi:10.1098/rspb.2012.1745 · Cited by 633 · see citing works
A semi-synthetic organism with an expanded genetic alphabet
Malyshev, D. A., Dhami, K., Lavergne, T., Chen, T., Dai, N., Foster, J. M., Junior, I. R. C., & Romesberg, F. E. (2014) · Nature · doi:10.1038/nature13314 · Cited by 614 · see citing works
Emerging technologies in DNA sequencingPreprint
Metzker, M. L. (2005) · Genome Research · doi:10.1101/gr.3770505 · Cited by 493 · see citing works
Complex wireframe DNA origami nanostructures with multi-arm junction vertices
Zhang, F., Jiang, S., Wu, S., Li, Y., Mao, C., Liu, Y., & Yan, H. (2015) · Nature Nanotechnology · doi:10.1038/nnano.2015.162 · Cited by 415 · see citing works
Hayden, E. C. (2014) · Nature · doi:10.1038/507294a · Cited by 409 · see citing works
Chemistry and Biology of DNA Repair
Schärer, O. D. (2003) · Angewandte Chemie International Edition · doi:10.1002/anie.200200523 · Cited by 381 · see citing works
Current progress in DNA barcoding and future implications for entomology
Jinbo, U., Kato, T., & Itô, M. (2011) · Entomological Science · doi:10.1111/j.1479-8298.2011.00449.x · Cited by 301 · see citing works
The expanding scope of DNA sequencing
Shendure, J., & Aiden, E. L. (2012) · Nature Biotechnology · doi:10.1038/nbt.2421 · Cited by 300 · see citing works
CTP synthase 1 deficiency in humans reveals its central role in lymphocyte proliferation
Martin, E., Palmic, N., Sanquer, S., Lenoir, C., Hauck, F. H., Mongellaz, C., Fabrega, S., Nitschké, P., Esposti, M. D., Schwartzentruber, J., et al. (2014) · Nature · doi:10.1038/nature13386 · Cited by 243 · see citing works
Carr, P. A., & Church, G. M. (2009) · Nature Biotechnology · doi:10.1038/nbt.1590 · Cited by 203 · see citing works
Self-citationReplication of individual DNA molecules under electronic control using a protein nanopore
Olasagasti, F., Lieberman, K. R., Benner, S., Cherf, G. M., Dahl, J. M., Deamer, D. W., & Akeson, M. A. (2010) · Nature Nanotechnology · doi:10.1038/nnano.2010.177 · Cited by 167 · see citing works
DNA Nanostructures as Programmable Biomolecular Scaffolds
Yang, Y. R., Liu, Y., & Yan, H. (2015) · Bioconjugate Chemistry · doi:10.1021/acs.bioconjchem.5b00194 · Cited by 150 · see citing works
Construction of a 4 Zeptoliters Switchable 3D DNA Box Origami
Zadegan, R. M., Jepsen, M. D. E., Thomsen, K. E., Okholm, A. H., Schaffert, D., Andersen, E. S., Birkedal, V., & Kjems, J. (2012) · ACS Nano · doi:10.1021/nn303767b · Cited by 130 · see citing works
Self-citationWaldrop, M. M. (2016) · Nature · Cited by 119 · see citing works
Construction of a Fuzzy and Boolean Logic Gates Based on DNA
Zadegan, R. M., Jepsen, M. D. E., Hildebrandt, L. L., Birkedal, V., & Kjems, J. (2015) · Small · doi:10.1002/smll.201402755 · Cited by 113 · see citing works
Self-citationRecent trends in nanopores for biotechnology
Stoloff, D. H., & Wanunu, M. (2012) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2012.11.008 · Cited by 108 · see citing works
A microfluidic oligonucleotide synthesizer
Lee, C.-C., Snyder, T. M., & Quake, S. R. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq092 · Cited by 94 · see citing works
Excitonic AND Logic Gates on DNA Brick Nanobreadboards
Cannon, B. L., Kellis, D. L., Davis, P. H., Lee, J., Kuang, W., Hughes, W. L., Graugnard, E., Yurke, B., & Knowlton, W. B. (2015) · ACS Photonics · doi:10.1021/ph500444d · Cited by 82 · see citing works
Self-citationProtocols for dry <scp>DNA</scp> storage and shipment at room temperature
Ivanova, N. V., & Kuzmina, M. L. (2013) · Molecular Ecology Resources · doi:10.1111/1755-0998.12134 · Cited by 72 · see citing works
Nanometer-Scale ${\rm HfO}_{x}$ RRAM
Zhang, Z., Wu, Y., Wong, H. ‐. P., & Wong, S. S. (2013) · IEEE Electron Device Letters · doi:10.1109/led.2013.2265404 · Cited by 56 · see citing works
Identification of ancient remains through genomic sequencingPreprint
Blow, M. J., Zhang, T., Woyke, T., Speller, C., Krivoshapkin, A., Yang, D. Y., Derevianko, A. P., & Rubin, E. M. (2008) · Genome Research · doi:10.1101/gr.076091.108 · Cited by 53 · see citing works
Photoelectrochemical synthesis of DNA microarrays
Chow, B. Y., Emig, C. J., & Jacobson, J. M. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813011106 · Cited by 48 · see citing works
DNA topology influences molecular machine lifetime in human serum
Goltry, S., Hallstrom, N., Clark, T., Kuang, W., Lee, J., Jorcyk, C. L., Knowlton, W. B., Yurke, B., Hughes, W. L., & Graugnard, E. (2015) · Nanoscale · doi:10.1039/c5nr02283e · Cited by 46 · see citing works
Self-citationXu, Z. (2014) · Journal of Computer Science and Technology · doi:10.1007/s11390-014-1420-2 · Cited by 44 · see citing works
Takabayashi, S., Klein, W. P., Onodera, C., Rapp, B., Flores-Estrada, J., Lindau, E. G., Snowball, L., Sam, J. T., Padilla, J. E., Lee, J., et al. (2014) · Nanoscale · doi:10.1039/c4nr03069a · Cited by 32 · see citing works
Self-citationMicroscale and nanoscale compartments for biotechnology
Retterer, S. T., & Simpson, M. L. (2012) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2012.01.002 · Cited by 14 · see citing works
Biological lithography: Improvements in DNA synthesis methods
Kim, C., Li, M., Rodesch, M. J., Lowe, A. M., Richmond, K. E., & Cerrina, F. (2004) · Journal of Vacuum Science & Technology B Microelectronics and Nanometer Structures Processing Measurement and Phenomena · doi:10.1116/1.1824066 · Cited by 11 · see citing works
Extending lifetime of flash memory using strong error correction coding
Kim, C., Park, C., Yoo, S., & Lee, S. (2015) · IEEE Transactions on Consumer Electronics · doi:10.1109/tce.2015.7150595 · Cited by 8 · see citing works
Flagged first, then by citations
Research works printed but not linked: 5
- [25]SemiSynBio Consortium and Roadmap Development (The National Institute of Standards and Technology, 2015); http://go.nature.com/PzwrM2
- [26]Bob K Past, Present and Future of DNA Sequencing (Illumina, 2013); http://go.nature.com/MtTrRk
- [35]Summary Report for the SRC Workshop on “Synergies between Semiconductors and Synthetic Biology” (SemiSynBio) (Semiconductor Research Corporation, 2013).
- [44]Kim C, Park C, Yoo S & Lee S IEEE Trans. Consum. Electron 61, 206– 214 (2015).
- [45]MinION MkI Oxford NanoPore Technologies http://go.nature.com/wYqldy
Cited by
Sorted by citations
Designer nanoscale DNA assemblies programmed from the top down
Veneziano, R., Ratanalert, S., Zhang, K., Zhang, F., Yan, H., Chiu, W., & Bathe, M. (2016) · Science · doi:10.1126/science.aaf4388 · Cited by 624 · see citing works
Molecular Digital Data Storage Using DNA
Ceze, L., Nivala, J., & Strauss, K. (2019) · Nature Reviews Genetics · doi:10.1038/s41576-019-0125-3 · Cited by 551 · see citing works
Portable and Error-Free DNA-Based Data Storage
Yazdi, S. M. H. T., Gabrys, R., & Milenkovic, O. (2017) · Scientific Reports · doi:10.1038/s41598-017-05188-1 · Cited by 361 · see citing works
CRISPR-Cas Encoding of a Digital Movie into the Genomes of a Population of Living Bacteria
Shipman, S. L., Nivala, J., Macklis, J. D., & Church, G. M. (2017) · Nature · doi:10.1038/nature23017 · Cited by 361 · see citing works
Self-citationEnzymatic DNA synthesis for digital information storage.
Lee, H. H., Kalhor, R., Goela, N., Bolot, J., & Church, G. M. (2018) · doi:10.1101/348987 · Cited by 265 · see citing works
Self-citationData storage in DNA with fewer synthesis cycles using composite DNA letters.
Anavy, L., Vaknin, I., Atar, O., Amit, R., & Yakhini, Z. (2019) · Nature Biotechnology · doi:10.1038/s41587-019-0240-x · Cited by 229 · see citing works
DNA storage: research landscape and future prospects
Dong, Y., Sun, F., Ping, Z., Ouyang, Q., & Qian, L. (2020) · National Science Review · doi:10.1093/nsr/nwaa007 · Cited by 224 · see citing works
Encoding information into polymers
Rutten, M. G. T. A., Vaandrager, F. W., Elemans, J. A. A. W., & Nolte, R. J. M. (2018) · Nature Reviews Chemistry · doi:10.1038/s41570-018-0051-5 · Cited by 216 · see citing works
DNA stability: a central design consideration for DNA data storage systems
Matange, K. R., Tuck, J. M., & Keung, A. J. (2021) · Nature Communications · doi:10.1038/s41467-021-21587-5 · Cited by 212 · see citing works
Defining the Field of Sequence‐Controlled Polymers
Lutz, J. (2017) · Macromolecular Rapid Communications · doi:10.1002/marc.201700582 · Cited by 202 · see citing works
Evolution of Structural DNA Nanotechnology
Nummelin, S., Kommeri, J., Kostiainen, M. A., & Linko, V. (2018) · Advanced Materials · doi:10.1002/adma.201703721 · Cited by 196 · see citing works
A DNA-of-things storage architecture to create materials with embedded memory.
Koch, J., Gantenbein, S., Masania, K., Stark, W. J., Erlich, Y., & Grass, R. N. (2020) · Nature Biotechnology · doi:10.1038/s41587-019-0356-z · Cited by 183 · see citing works
Multifunctional sequence-defined macromolecules for chemical data storage.
Martens, S., Landuyt, A., Espeel, P., Devreese, B., Dawyndt, P., & Du Prez, F. (2018) · Nature Communications · doi:10.1038/s41467-018-06926-3 · Cited by 180 · see citing works
Towards practical and robust DNA-based data archiving using the yin–yang codec system
Ping, Z., Chen, S., Zhou, G., Huang, X., Zhu, S. J., Zhang, H., Lee, H. H., Lan, Z., Cui, J., Chen, T., et al. (2022) · Nature Computational Science · doi:10.1038/s43588-022-00231-2 · Cited by 148 · see citing works
Self-citationRandom access DNA memory using Boolean search in an archival file storage system
Banal, J. L., Shepherd, T. R., Berleant, J., Huang, H., Reyes, M., Ackerman, C. M., Blainey, P. C., & Bathe, M. (2021) · Nature Materials · doi:10.1038/s41563-021-01021-3 · Cited by 143 · see citing works
DNA assembly for nanopore data storage readout
Lopez, R., Chen, Y.-J., Dumas Ang, S., Yekhanin, S., Makarychev, K., Racz, M. Z., Seelig, G., Strauss, K., & Ceze, L. (2019) · Nature Communications · doi:10.1038/s41467-019-10978-4 · Cited by 142 · see citing works
An Artificial Chromosome for Data Storage
Chen, W., Han, M., Zhou, J., Ge, Q., Wang, P., Zhang, X., Zhu, S., Song, L., & Yuan, Y. (2021) · National Science Review · doi:10.1093/nsr/nwab028 · Cited by 136 · see citing works
Probing the physical limits of reliable DNA data retrieval.
Organick, L., Chen, Y.-J., Dumas Ang, S., Lopez, R., Liu, X., Strauss, K., & Ceze, L. (2020) · Nature Communications · doi:10.1038/s41467-020-14319-8 · Cited by 135 · see citing works
Phototunable Biomemory Based on Light‐Mediated Charge Trap
Lv, Z., Wang, Y., Chen, Z., Sun, L., Wang, J., Chen, M., Xu, Z., Liao, Q., Zhou, L., Chen, X., et al. (2018) · Advanced Science · doi:10.1002/advs.201800714 · Cited by 134 · see citing works
DNA as a universal chemical substrate for computing and data storage
Yang, S., Bögels, B. W. A., Wang, F., Xu, C., Dou, H., Mann, S., Fan, C., & de Greef, T. F. A. (2024) · Nature Reviews Chemistry · doi:10.1038/s41570-024-00576-4 · Cited by 142 · see citing works
Ouahabi, A. A., Amalian, J., Charles, L., & Lutz, J. (2017) · Nature Communications · doi:10.1038/s41467-017-01104-3 · Cited by 132 · see citing works
Aksakal, R., Mertens, C., Soete, M., Badi, N., & Prez, F. D. (2021) · Advanced Science · doi:10.1002/advs.202004038 · Cited by 135 · see citing works
Choi, Y., Ryu, T., Lee, A. C., Choi, H., Lee, H., Park, J., Song, S.-H., Kim, S., Kim, H., Park, W., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-43105-w · Cited by 128 · see citing works
Synthetic DNA applications in information technology
Meiser, L. C., Nguyen, B. H., Chen, Y.-J., Nivala, J., Strauß, K., Ceze, L., & Grass, R. N. (2022) · Nature Communications · doi:10.1038/s41467-021-27846-9 · Cited by 129 · see citing works
How DNA could store all the world’s data
Extance, A. (2016) · Nature · doi:10.1038/537022a · Cited by 123 · see citing works
DNA punch cards for storing data on native DNA sequences via enzymatic nicking
Tabatabaei, S. K., Wang, B., Athreya, N. B. M., Enghiad, B., Hernandez, A. G., Fields, C. J., Leburton, J.-P., Soloveichik, D., Zhao, H., & Milenkovic, O. (2020) · Nature Communications · doi:10.1038/s41467-020-15588-z · Cited by 120 · see citing works
Dynamic and scalable DNA-based information storage
Lin, K. N., Volkel, K., Tuck, J. M., & Keung, A. J. (2020) · Nature Communications · doi:10.1038/s41467-020-16797-2 · Cited by 117 · see citing works
Photon-directed multiplexed enzymatic DNA synthesis for molecular digital data storage
Lee, H., Wiegand, D. J., Griswold, K., Punthambaker, S., Chun, H., Kohman, R. E., & Church, G. M. (2020) · Nature Communications · doi:10.1038/s41467-020-18681-5 · Cited by 116 · see citing works
Self-citationData storage in sequence-defined macromolecules via multicomponent reactions
Boukis, A. C., & Meier, M. A. R. (2018) · European Polymer Journal · doi:10.1016/j.eurpolymj.2018.04.038 · Cited by 111 · see citing works
Quantifying Molecular Bias in DNA Data Storage
Chen, Y.-J., Takahashi, C. N., Organick, L., Stewart, K., Ang, S. D., Weiss, P., Peck, B., Seelig, G., Ceze, L., & Strauss, K. (2019) · doi:10.1101/566554 · Cited by 109 · see citing works
Storage of Information Using Small Organic Molecules
Cafferty, B. J., Ten, A. S., Fink, M. J., Morey, S., Preston, D. J., Mrksich, M., & Whitesides, G. M. (2019) · ACS Central Science · doi:10.1021/acscentsci.9b00210 · Cited by 107 · see citing works
Robust data storage in DNA by de Bruijn graph-based de novo strand assembly
Song, L., Geng, F., Gong, Z.-Y., Chen, X., Tang, J., Gong, C., Zhou, L., Xia, R., Han, M., Xu, J.-Y., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-33046-w · Cited by 98 · see citing works
Driving the Scalability of DNA-Based Information Storage Systems
Tomek, K. J., Volkel, K., Simpson, A., Hass, A. G., Indermaur, E. W., Tuck, J. M., & Keung, A. J. (2019) · ACS Synthetic Biology · doi:10.1021/acssynbio.9b00100 · Cited by 100 · see citing works
Laure, C., Karamessini, D., Milenković, O., Charles, L., & Lutz, J. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201605279 · Cited by 87 · see citing works
High-throughput DNA synthesis for data storage
Yu, M., Tang, X., Li, Z., Wang, W., Wang, S., Li, M., Yu, Q., Xie, S., Zuo, X., & Chen, C. Q. (2024) · Chemical Society Reviews · doi:10.1039/d3cs00469d · Cited by 90 · see citing works
An alternative approach to nucleic acid memory
Dickinson, G. D., Mortuza, G. M., Clay, W., Piantanida, L., Green, C. M., Watson, C., Hayden, E. J., Andersen, T., Kuang, W., Graugnard, E., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-22277-y · Cited by 82 · see citing works
Self-citationRewritable two-dimensional DNA-based data storage with machine learning reconstruction
Pan, C., Tabatabaei, S. K., Yazdi, S. M. H. T., Hernandez, A. G., Schroeder, C. M., & Milenković, O. (2022) · Nature Communications · doi:10.1038/s41467-022-30140-x · Cited by 82 · see citing works
Addressable configurations of DNA nanostructures for rewritable memory
Chandrasekaran, A. R., Levchenko, O., Patel, D. S., MacIsaac, M., & Halvorsen, K. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkx777 · Cited by 79 · see citing works
Choi, Y., Bae, H. J., Lee, A. C., Choi, H., Lee, D., Ryu, T., Hyun, J., Kim, S., Kim, H., Song, S., et al. (2020) · Advanced Materials · doi:10.1002/adma.202001249 · Cited by 77 · see citing works
Song, L.-F., Deng, Z.-H., Gong, Z.-Y., Li, L.-L., & Li, B.-Z. (2021) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2021.689797 · Cited by 74 · see citing works
Multicomponent molecular memory
Arcadia, C. E., Kennedy, E., Geiser, J. D., Dombroski, A., Oakley, K., Chen, S., Sprague, L. W., Ozmen, M., Sello, J. K., Weber, P. M., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-14455-1 · Cited by 74 · see citing works
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König, N. F., Ouahabi, A. A., Oswald, L., Szweda, R., Charles, L., & Lutz, J. (2019) · Nature Communications · doi:10.1038/s41467-019-11566-2 · Cited by 74 · see citing works
Nucleic Acid Databases and Molecular-Scale Computing
Song, X., & Reif, J. (2019) · ACS Nano · doi:10.1021/acsnano.9b02562 · Cited by 73 · see citing works
DNA Data Storage and Hybrid Molecular–Electronic Computing
Carmean, D., Ceze, L., Seelig, G., Stewart, K., Strauss, K., & Willsey, M. (2019) · Proceedings of the IEEE · doi:10.1109/jproc.2018.2875386 · Cited by 69 · see citing works
König, N. F., Ouahabi, A. A., Poyer, S., Charles, L., & Lutz, J. (2017) · Angewandte Chemie International Edition · doi:10.1002/anie.201702384 · Cited by 69 · see citing works
Uncertainties in synthetic DNA-based data storage
Xu, C., Zhao, C., Ma, B., & Liu, H. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab230 · Cited by 65 · see citing works
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Zhu, J., Ermann, N., Chen, K., & Keyser, U. F. (2021) · Small · doi:10.1002/smll.202100711 · Cited by 66 · see citing works
Enabling technology and core theory of synthetic biology
Zhang, X., Liu, C., Dai, J., Yuan, Y., Gao, C., Feng, Y. F., Wu, B., Wei, P., You, C., Wang, X., et al. (2023) · Science China Life Sciences · doi:10.1007/s11427-022-2214-2 · Cited by 65 · see citing works
Tabatabaei, S. K., Pham, B., Pan, C., Liu, J., Chandak, S., Shorkey, S. A., Hernandez, A. G., Aksimentiev, A., Chen, M., Schroeder, C. M., et al. (2022) · Nano Letters · doi:10.1021/acs.nanolett.1c04203 · Cited by 63 · see citing works
Semiautomated synthesis of sequence-defined polymers for information storage
Lee, J. M., Kwon, J.-H., Lee, S. J., Jang, H., Kim, D., Song, J., & Kim, K. T. (2022) · Science Advances · doi:10.1126/sciadv.abl8614 · Cited by 62 · see citing works
High-Capacity Digital Polymers: Storing Images in Single Molecules
Laurent, E., Amalian, J., Parmentier, M., Oswald, L., Ouahabi, A. A., Dufour, F., Launay, K., Jean-Louis, C., Gigmès, D., Delsuc, M., et al. (2020) · Macromolecules · doi:10.1021/acs.macromol.0c00666 · Cited by 62 · see citing works
DNA as a digital information storage device: hope or hype?
Panda, D., Molla, K. A., Baig, M. J., Swain, A., Behera, D., & Dash, M. (2018) · 3 Biotech · doi:10.1007/s13205-018-1246-7 · Cited by 64 · see citing works
Storing and Reading Information in Mixtures of Fluorescent Molecules
Nagarkar, A. A., Root, S. E., Fink, M. J., Ten, A. S., Cafferty, B. J., Richardson, D. S., Mrksich, M., & Whitesides, G. M. (2021) · ACS Central Science · doi:10.1021/acscentsci.1c00728 · Cited by 57 · see citing works
MS-DECODER: Milliseconds Sequencing of Coded Polymers
Burel, A., Carapito, C., Lutz, J., & Charles, L. (2017) · Macromolecules · doi:10.1021/acs.macromol.7b01737 · Cited by 52 · see citing works
Digital synthetic polymers for information storage
Yu, L., Chen, B., Li, Z., Huang, Q., He, K., Su, Y., Han, Z., Zhou, Y., Zhu, X., Yan, D., et al. (2023) · Chemical Society Reviews · doi:10.1039/d2cs01022d · Cited by 49 · see citing works
Information stored in nanoscale: Encoding data in a single DNA strand with Base64
Zhang, Y., Kong, L., Wang, F., Li, B., Ma, C., Chen, D., Liu, K., Fan, C., & Zhang, H. (2020) · Nano Today · doi:10.1016/j.nantod.2020.100871 · Cited by 48 · see citing works
Fei, Z., Gupta, N., Li, M., Xiao, P., & Hu, X. (2023) · Science Advances · doi:10.1126/sciadv.adg9933 · Cited by 47 · see citing works
Song, Y., Kim, S., Heller, M. J., & Huang, X. C. (2018) · Nature Communications · doi:10.1038/s41467-017-02705-8 · Cited by 47 · see citing works
Dahlhauser, S. D., Wight, C. D., Moor, S. R., Scanga, R. A., Ngo, P. H. T., York, J. T., Vera, M. S., Blake, K. J., Riddington, I. M., Reuther, J. F., et al. (2022) · ACS Central Science · doi:10.1021/acscentsci.2c00460 · Cited by 48 · see citing works
Producing highly complicated materials. Nature does it better
Bindi, L., Nespolo, M., Krivovichev, S. V., Chapuis, G., & Biagioni, C. (2020) · Reports on Progress in Physics · doi:10.1088/1361-6633/abaa3a · Cited by 45 · see citing works
Novel Modalities in DNA Data Storage
Lim, C. K., Nirantar, S., Yew, W. S., & Poh, C. L. (2021) · Trends in biotechnology · doi:10.1016/j.tibtech.2020.12.008 · Cited by 44 · see citing works
Reading Information Stored in Synthetic Macromolecules
Soete, M., Mertens, C., Badi, N., & Prez, F. D. (2022) · Journal of the American Chemical Society · doi:10.1021/jacs.2c10316 · Cited by 41 · see citing works
Rapidly sequence-controlled electrosynthesis of organometallic polymers
Zhang, J., Wang, J., Wei, C., Wang, Y., Xie, G., Li, Y., & Li, M. (2020) · Nature Communications · doi:10.1038/s41467-020-16255-z · Cited by 42 · see citing works
An outlook on the current challenges and opportunities in DNA data storage
Raza, M. H., Desai, S. S., Aravamudhan, S., & Zadegan, R. M. (2023) · Biotechnology Advances · doi:10.1016/j.biotechadv.2023.108155 · Cited by 40 · see citing works
Self-citationSubmillimetre Network Formation by Light-induced Hybridization of Zeptomole-level DNA
Iida, T., Nishimura, Y., Tamura, M., Nishida, K., Ito, S., & Tokonami, S. (2016) · Scientific Reports · doi:10.1038/srep37768 · Cited by 40 · see citing works
Szweda, R., Tschopp, M., Félix, O., Decher, G., & Lutz, J. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201810559 · Cited by 40 · see citing works
Inscribed Matter Communication: Part I
Rose, C., & Mian, S. I. (2016) · IEEE Transactions on Molecular Biological and Multi-Scale Communications · doi:10.1109/tmbmc.2017.2655025 · Cited by 40 · see citing works
Furuhata, T., Ohshiro, T., Akimoto, G., Ueki, R., Taniguchi, M., & Sando, S. (2019) · ACS Nano · doi:10.1021/acsnano.9b01250 · Cited by 39 · see citing works
Damage and Repair in Informational Poly( N ‐substituted urethane)s
Mondal, T., Charles, L., & Lutz, J. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202008864 · Cited by 38 · see citing works
Li, K., Lu, X., Liao, J., Chen, H., Wei, L., Zhao, Y., Tang, D., Li, C., Tian, Z., Zhu, Z., et al. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2410164121 · Cited by 36 · see citing works
Sequence-Encoded Macromolecules with Increased Data Storage Capacity through a Thiol-Epoxy Reaction
Soete, M., Mertens, C., Aksakal, R., Badi, N., & Prez, F. D. (2021) · ACS Macro Letters · doi:10.1021/acsmacrolett.1c00275 · Cited by 36 · see citing works
Molecular access to multi-dimensionally encoded information
Steinkoenig, J., Aksakal, R., & Prez, F. D. (2019) · European Polymer Journal · doi:10.1016/j.eurpolymj.2019.109260 · Cited by 35 · see citing works
Digital data storage on DNA tape using CRISPR base editors
Sadremomtaz, A., Glass, R. F., Guerrero, J. E., LaJeunesse, D., Josephs, E. A., & Zadegan, R. M. (2023) · Nature Communications · doi:10.1038/s41467-023-42223-4 · Cited by 35 · see citing works
Self-citationFractal construction of constrained code words for DNA storage systems
Löchel, H. F., Welzel, M., Hattab, G., Hauschild, A.-C., & Heider, D. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab1209 · Cited by 32 · see citing works
Promiscuous molecules for smarter file operations in DNA-based data storage
Tomek, K. J., Volkel, K., Indermaur, E. W., Tuck, J. M., & Keung, A. J. (2021) · Nature Communications · doi:10.1038/s41467-021-23669-w · Cited by 35 · see citing works
Rewritable Macromolecular Data Storage with Automated Read‐out
Soete, M., Bruycker, K. D., & Prez, F. D. (2022) · Angewandte Chemie International Edition · doi:10.1002/anie.202116718 · Cited by 33 · see citing works
Design considerations for advancing data storage with synthetic DNA for long-term archiving
Ezekannagha, C., Becker, A., Heider, D., & Hattab, G. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100306 · Cited by 31 · see citing works
Improving error-correcting capability in DNA digital storage via soft-decision decoding
Ding, L., Wu, S., Hou, Z., Li, A., Xu, Y., Feng, H., Pan, W., & Ruan, J. (2023) · National Science Review · doi:10.1093/nsr/nwad229 · Cited by 27 · see citing works
Functionalized Silicon Electrodes in Electrochemistry
Gonçales, V. R., Lian, J., Gautam, S., Tilley, R. D., & Gooding, J. J. (2020) · Annual Review of Analytical Chemistry · doi:10.1146/annurev-anchem-091619-092506 · Cited by 30 · see citing works
Concepts and Application of DNA Origami and DNA Self-Assembly: A Systematic Review
Liu, W., Duan, H., Zhang, D., Zhang, X., Luo, Q., Xie, T., Yan, H., Peng, L., Hu, Y., Li, L., et al. (2021) · Applied Bionics and Biomechanics · doi:10.1155/2021/9112407 · Cited by 30 · see citing works
Principles of Information Storage in Small-Molecule Mixtures
Rosenstein, J. K., Rose, C., Reda, S., Weber, P. M., Kim, E., Sello, J. K., Geiser, J. D., Kennedy, E., Arcadia, C. E., Dombroski, A., et al. (2020) · IEEE Transactions on NanoBioscience · doi:10.1109/tnb.2020.2977304 · Cited by 31 · see citing works
Scaling logical density of DNA storage with enzymatically-ligated composite motifs
Yan, Y., Pinnamaneni, N., Chalapati, S., Crosbie, C., & Appuswamy, R. (2023) · Scientific Reports · doi:10.1038/s41598-023-43172-0 · Cited by 29 · see citing works
Autonomous Computing Materials
Bathe, M., Hernandez, R., Komiyama, T., Machiraju, R., & Neogi, S. (2021) · ACS Nano · doi:10.1021/acsnano.0c09556 · Cited by 28 · see citing works
Preservation and Encryption in DNA Digital Data Storage
Zhang, Y., Ren, Y., Liu, Y., Wang, F., Zhang, H., & Liu, K. (2022) · ChemPlusChem · doi:10.1002/cplu.202200183 · Cited by 28 · see citing works
A mirror-image protein-based information barcoding and storage technology
Zheng, J., Liang, J., Shi, W., Li, Y., Hu, H., Tian, C., & Liu, L. (2021) · 中国科学通报：英文版 · doi:10.1016/j.scib.2021.03.010 · Cited by 27 · see citing works
Twisting of DNA Origami from Intercalators
Zadegan, R. M., Lindau, E. G., Klein, W. P., Green, C. M., Graugnard, E., Yurke, B., Kuang, W., & Hughes, W. L. (2017) · Scientific Reports · doi:10.1038/s41598-017-07796-3 · Cited by 26 · see citing works
Self-citationChemically Modified Aptamers in Biological Analysis
Shen, R., Tan, J., & Yuan, Q. (2020) · ACS Applied Bio Materials · doi:10.1021/acsabm.0c00062 · Cited by 26 · see citing works
Empowering DNA-Based Information Processing: Computation and Data Storage
Li, K., Chen, H., Li, D., Yang, C. J., Zhang, H., & Zhu, Z. (2024) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.4c13948 · Cited by 25 · see citing works
Decoding DNA data storage for investment
Stanley, P. M., Strittmatter, L. M., Vickers, A., & Lee, K. C. K. (2020) · Biotechnology Advances · doi:10.1016/j.biotechadv.2020.107639 · Cited by 24 · see citing works
Storing the portrait of Antoine de Lavoisier in a single macromolecule
Laurent, E., Amalian, J., Schutz, T., Launay, K., Jean-Louis, C., Gigmès, D., Burel, A., Carapito, C., Charles, L., Delsuc, M., et al. (2021) · Comptes Rendus Chimie · doi:10.5802/crchim.72 · Cited by 25 · see citing works
About the Crystallization of Abiotic Coded Matter
Petit, B. É., Lotz, B., & Lutz, J. (2019) · ACS Macro Letters · doi:10.1021/acsmacrolett.9b00307 · Cited by 24 · see citing works
Launay, K., Amalian, J., Laurent, E., Oswald, L., Ouahabi, A. A., Burel, A., Dufour, F., Carapito, C., Jean-Louis, C., Lutz, J., et al. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202010171 · Cited by 24 · see citing works
Wu, W., Xiang, L., Liu, Q., & Yang, K. (2023) · IEEE Transactions on Molecular Biological and Multi-Scale Communications · doi:10.1109/tmbmc.2023.3331579 · Cited by 23 · see citing works
Recent Progress in High-Throughput Enzymatic DNA Synthesis for Data Storage
Baek, D. J., Joe, S.-Y., Shin, H., Park, C., Jo, S., & Chun, H. (2024) · BioChip Journal · doi:10.1007/s13206-024-00146-2 · Cited by 24 · see citing works
DeSP: a systematic DNA storage error simulation pipeline
Yuan, L., Xie, Z., Wang, Y., & Wang, X. (2022) · BMC Bioinformatics · doi:10.1186/s12859-022-04723-w · Cited by 22 · see citing works
DNA-based data storage via combinatorial assemblyPreprint
Roquet, N., Bhatia, S. P., Flickinger, S. A., Mihm, S., Norsworthy, M. W., Leake, D., & Park, H. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.04.20.440194 · Cited by 24 · see citing works
Multi-resolution simulation of DNA transport through large synthetic nanostructures
Choudhary, A., Maffeo, C., & Aksimentiev, A. (2022) · Physical Chemistry Chemical Physics · doi:10.1039/d1cp04589j · Cited by 22 · see citing works
A biological camera that captures and stores images directly into DNA
Lim, C. K., Yeoh, J. W., Kunartama, A. A., Yew, W. S., & Poh, C. L. (2023) · Nature Communications · doi:10.1038/s41467-023-38876-w · Cited by 24 · see citing works
Buko, T., Tuczko, N., & Ishikawa, T. (2023) · BioTech · doi:10.3390/biotech12020044 · Cited by 21 · see citing works
CLGBO: An Algorithm for Constructing Highly Robust Coding Sets for DNA Storage
Zheng, Y., Wu, J., & Wang, B. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.644945 · Cited by 21 · see citing works
- Authors
- Zhirnov, V., Zadegan, R. M., Sandhu, G. S., Church, G. M., & Hughes, W. L.
- Affiliations
- Semiconductor Research Corporation (US)
- Boise State University (US)
- Micron (United States) (US)
- Harvard University (US)
- Corresponding author
- Church, George M.
- Hughes, William L.
- Venue
- Nature Materials
- Published
- 2016-03-23
- Volume
- 15
- Issue
- 4
- Pages
- 366-370
- ISSN
- 1476-1122 (ISSN-L)
- 1476-4660
- PMC
- PMC6361517
- OpenAlex
- W2302781903
- Cited by
- 307
- References
- 43
- Citations by year
- 2026: 23 · 2025: 38 · 2024: 42 · 2023: 41 · 2022: 40 · 2021: 35 · 2020: 31 · 2019: 22 · 2018: 15 · 2017: 13 · 2016: 7
- FWCI
- 8.12
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Nature Materials (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Scholar Works (Boise State University) (submittedVersion)
- Funders
- National Institute of General Medical Sciences (K25GM093233)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Biological Computing
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced Memory and Neural Computing
- Physical Sciences › Computer Science › Computer Networks and Communications › Advanced Data Storage Technologies
- Keywords
- DNA data storage, DNA strand displacement, information retention, storage density, energy efficiency
- MeSH terms
- Nucleic Acids, Information Storage and Retrieval
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