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Genome-encoded ABCF factors implicated in intrinsic antibiotic resistance in Gram-positive bacteria: VmlR2, Ard1 and CplR

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Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling

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Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S

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Structural basis of the bacterial flagellar motor rotational switching

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Structural basis of host protein hijacking in human T-cell leukemia virus integration

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SHIP164 is a chorein motif lipid transfer protein that controls endosome–Golgi membrane traffic

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Structural Insights into the Activation of Human Aryl Hydrocarbon Receptor by the Environmental Contaminant Benzo[a]pyrene and Structurally Related Compounds

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Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation

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Lattice defects induced by microtubule-stabilizing agents exert a long-range effect on microtubule growth by promoting catastrophes

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Structural insights into TRAP association with ribosome-Sec61 complex and translocon inhibition by a CADA derivative

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Structural basis of substrate recognition and translocation by human very long-chain fatty acid transporter ABCD1

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CryoEM structure of the type IVa pilus secretin required for natural competence in Vibrio cholerae

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A wheat resistosome defines common principles of immune receptor channels

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Cryo-EM structure of the Smc5/6 holo-complex

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Cryo-EM structures of an LRRC8 chimera with native functional properties reveal heptameric assembly

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Mammalian PIWI–piRNA–target complexes reveal features for broad and efficient target silencing

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Structural basis for the activation of a compact CRISPR-Cas13 nuclease

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Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans

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Broadly inhibitory antibodies to severe malaria virulence proteins

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‘Generating chromosome geometries in a minimal cell from cryo-electron tomograms and chromosome conformation capture maps’

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Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

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Structural mechanism of outer kinetochore Dam1-Ndc80 complex assembly on microtubules

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Structural insight into Tn3 family transposition mechanism

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Architecture of the Tuberous Sclerosis Protein Complex

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Structural pathway for PI3-kinase regulation by VPS15 in autophagy

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The giant mimivirus 1.2 Mb genome is elegantly organized into a 30-nm diameter helical protein shield

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De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex

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Structural conservation of insulin/IGF signalling axis at the insulin receptors level in Drosophila and humans

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Visualising the cytoskeletal machinery in neuronal growth cones using cryo-electron tomography

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Structure comparison of the chimeric AAV2.7m8 vector with parental AAV2

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Cryo-EM structure of the inner ring from the Xenopus laevis nuclear pore complex

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Molecular architecture of synaptic vesicles

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Molecular mechanism of substrate recognition by folate transporter SLC19A1

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Cryo-EM structure of the β-1,3-glucan synthase FKS1-Rho1 complex

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Rieske head domain dynamics and indazole-derivative inhibition of Candida albicans complex III

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Mouse α-synuclein fibrils are structurally and functionally distinct from human fibrils associated with Lewy body diseases

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Molecular basis of mRNA delivery to the bacterial ribosome

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The kidney slit diaphragm resembles a fishnet

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Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

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Molecular insights into human phosphatidylserine synthase 1 reveal its inhibition promotes LDL uptake

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Cryo‐EM structures of human ABCA7 provide insights into its phospholipid translocation mechanisms

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Structures of tweety homolog proteins TTYH2 and TTYH3 reveal a Ca2+-dependent switch from intra- to intermembrane dimerization

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Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation

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Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant

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Structure of mycobacterial respiratory complex I

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Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane

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Structure-based electron-confurcation mechanism of the Ldh-EtfAB complex

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Structural basis of plp2-mediated cytoskeletal protein folding by TRiC/CCT

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Archaeal bundling pili of Pyrobaculum calidifontis reveal similarities between archaeal and bacterial biofilms

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Asgard archaea reveal the conserved principles of ESCRT-III membrane remodeling

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Structural basis for pre-tRNA recognition and processing by the human tRNA splicing endonuclease complex

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Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System

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Structural basis for the activity and regulation of human α-ketoglutarate dehydrogenase revealed by Cryo-EM

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