Recent advances in the genetic epidemiology and molecular genetics of substance use disorders

Diagnostic and Statistical Manual of Mental Disorders

Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works

The Fagerstrom Test for Nicotine Dependence: a revision of the Fagerstrom Tolerance Questionnaire

HEATHERTON, T. F., KOZLOWSKI, L. T., FRECKER, R. C., & FAGERSTROM, K. (1991) · British Journal of Addiction · doi:10.1111/j.1360-0443.1991.tb01879.x · Cited by 10,738 · see citing works

Neurocircuitry of Addiction

Koob, G. F., & Volkow, N. D. (2010) · Neuropsychopharmacology · doi:10.1038/npp.2009.110 · Cited by 5,340 · see citing works

Integrating Person‐Centered and Variable‐Centered Analyses: Growth Mixture Modeling With Latent Trajectory Classes

Muthén, B., & Muthén, L. K. (2000) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2000.tb02070.x · Cited by 3,161 · see citing works

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

Thorgeirsson, T. E., Geller, F., Sulem, P., Rafnar, T., Wiste, A., Magnusson, K. P., Manolescu, A., Thorleifsson, G., Stefansson, H., Ingason, A., et al. (2008) · Nature · doi:10.1038/nature06846 · Cited by 1,523 · see citing works

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Amos, C. I., Wu, X., Broderick, P., Gorlov, I. P., Gu, J., Eisen, T., Dong, Q., Zhang, Q., Gu, X., Vijayakrishnan, J., et al. (2008) · Nature Genetics · doi:10.1038/ng.109 · Cited by 1,310 · see citing works

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

Hung, R. J., McKay, J. D., Gaborieau, V., Boffetta, P., Hashibe, M., Zaridze, D., Mukeria, A., Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P., et al. (2008) · Nature · doi:10.1038/nature06885 · Cited by 1,275 · see citing works

The genetics of addictions: uncovering the genes

Goldman, D., Oroszi, G., & Ducci, F. (2005) · Nature Reviews Genetics · doi:10.1038/nrg1635 · Cited by 1,099 · see citing works

Genome-wide meta-analyses identify multiple loci associated with smoking behavior

The Tobacco and Genetics Consortium (2010) · Nature Genetics · doi:10.1038/ng.571 · Cited by 1,098 · see citing works

A Role for Brain Stress Systems in Addiction

Koob, G. F. (2008) · Neuron · doi:10.1016/j.neuron.2008.06.012 · Cited by 1,056 · see citing works

Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs

Saccone, S. F., Hinrichs, A. L., Saccone, N. L., Chase, G. A., Konvicka, K., Madden, P. A. F., Breslau, N., Johnson, E. O., Hatsukami, D., Pomerleau, O., et al. (2007) · Human Molecular Genetics · doi:10.1093/hmg/ddl438 · Cited by 850 · see citing works

Co-occurrence of Abuse of Different Drugs in Men: The Role of Drug-Specific and Shared Vulnerabilities

Tsuang, M. T., Lyons, M. J., Meyer, J. M., Doyle, T., Eisen, S. A., Goldberg, J., True, W., Lin, N., Toomey, R., & Eaves, L. (1998) · Archives of General Psychiatry · doi:10.1001/archpsyc.55.11.967 · Cited by 710 · see citing works

Specificity of Genetic and Environmental Risk Factors for Use and Abuse/Dependence of Cannabis, Cocaine, Hallucinogens, Sedatives, Stimulants, and Opiates in Male Twins

Kendler, K. S., Jacobson, K. C., Prescott, C. A., & Neale, M. C. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.4.687 · Cited by 693 · see citing works

Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior

The ENGAGE Consortium, Thorgeirsson, T. E., Gudbjartsson, D. F., Surakka, I., Vink, J. M., Amin, N., Geller, F., Sulem, P., Rafnar, T., Esko, T., et al. (2010) · Nature Genetics · doi:10.1038/ng.573 · Cited by 689 · see citing works

Variations in GABRA2, Encoding the α2 Subunit of the GABAA Receptor, Are Associated with Alcohol Dependence and with Brain Oscillations

Edenberg, H. J., Dick, D. M., Xuei, X., Tian, H., Almasy, L., Bauer, L. O., Crowe, R. R., Goate, A., Hesselbrock, V., Jones, K., et al. (2004) · The American Journal of Human Genetics · doi:10.1086/383283 · Cited by 655 · see citing works

Variants in Nicotinic Receptors and Risk for Nicotine Dependence

Bierut, L. J., Stitzel, J. A., Wang, J. C., Hinrichs, A. L., Grucza, R. A., Xuei, X., Saccone, N. L., Saccone, S. F., Bertelsen, S., Fox, L., et al. (2008) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2008.07111711 · Cited by 648 · see citing works

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

The Wellcome Trust Case Control Consortium, Liu, J. Z., Tozzi, F., Waterworth, D. M., Pillai, S. G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C. W., Yuan, X., et al. (2010) · Nature Genetics · doi:10.1038/ng.572 · Cited by 614 · see citing works

Distribution of ADH2 and ALDH2 genotypes in different populations

Goedde, H. W., Agarwal, D. P., Fritze, G., Meier-Tackmann, D., Singh, S., Beckmann, G., Bhatia, K., Chen, L. Z., Fang, B., Lisker, R., et al. (1992) · Human Genetics · doi:10.1007/bf00197271 · Cited by 564 · see citing works

A meta‐analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins

Li, M. D., Cheng, R., Ma, J. Z., & Swan, G. E. (2002) · Addiction · doi:10.1046/j.1360-0443.2003.00295.x · Cited by 554 · see citing works

Models for the joint effect of genotype and environment on liability to psychiatric illness

Kendler, K. S., & Eaves, L. J. (1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.3.279 · Cited by 549 · see citing works

The role of GABAA receptors in the acute and chronic effects of ethanol

Grobin, A., Matthews, D. B., Devaud, L., & Morrow, A. (1998) · Psychopharmacology · doi:10.1007/s002130050685 · Cited by 498 · see citing works

Genetic and Environmental Influences on Alcohol, Caffeine, Cannabis, and Nicotine Use From Early Adolescence to Middle Adulthood

Kendler, K. S., Schmitt, J. E., Aggen, S. H., & Prescott, C. A. (2008) · Archives of General Psychiatry · doi:10.1001/archpsyc.65.6.674 · Cited by 488 · see citing works

α-5/α-3 nicotinic receptor subunit alleles increase risk for heavy smoking

Berrettini, W., Yuan, X., Tozzi, F., Song, K., Francks, C., Chilcoat, H., Waterworth, D., Muglia, P., & Mooser, V (2008) · Molecular Psychiatry · doi:10.1038/sj.mp.4002154 · Cited by 465 · see citing works

A genome-wide association study of alcohol dependence

Bierut, L. J., Agrawal, A., Bucholz, K. K., Doheny, K. F., Laurie, C., Pugh, E., Fisher, S., Fox, L., Howells, W., Bertelsen, S., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0911109107 · Cited by 457 · see citing works

Nicotine addiction and nicotinic receptors: lessons from genetically modified mice

Changeux, J.-P. (2010) · Nature Reviews Neuroscience · doi:10.1038/nrn2849 · Cited by 453 · cited 1× · see citing works

A population-based twin study in women of smoking initiation and nicotine dependence

Kendler, K. S., Neale, M. C., Sullivan, P. F., Corey, L. A., GARDNER, C. O., & Prescott, C. A. (1999) · Psychological Medicine · doi:10.1017/s0033291798008022 · Cited by 438 · see citing works

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

Saccone, N. L., Culverhouse, R. C., Schwantes-An, T.-H., Cannon, D. S., Chen, X., Cichon, S., Giegling, I., Han, S., Han, Y., Keskitalo-Vuokko, K., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001053 · Cited by 395 · see citing works

Evidence for genetic linkage to alcohol dependence on chromosomes 4 and 11 from an autosome-wide scan in an american indian population

Long, J. C., Knowler, W. C., Hanson, R. L., Robin, R. W., Urbanek, M., Moore, E., Bennett, P. H., & Goldman, D. A. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19980508)81:3 · Cited by 389 · see citing works

Genome-wide Association Study of Alcohol Dependence

Treutlein, J., Cichon, S., Ridinger, M., Wodarz, N., Soyka, M., Zill, P., Maier, W., Moessner, R., Gäebel, W., Dahmen, N., et al. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.83 · Cited by 380 · see citing works

The Structure of Genetic and Environmental Risk Factors for Syndromal and Subsyndromal Common DSM-IV Axis I and All Axis II Disorders

Kendler, K. S., Aggen, S. H., Knudsen, G. P., Røysamb, E., Neale, M. C., & Reichborn‐Kjennerud, T. (2010) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10030340 · Cited by 368 · see citing works

Specificity of Genetic and Environmental Risk Factors for Symptoms of Cannabis, Cocaine, Alcohol, Caffeine, and Nicotine Dependence

Kendler, K. S., Myers, J., & Prescott, C. A. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.11.1313 · Cited by 363 · see citing works

A Central Role of the BK Potassium Channel in Behavioral Responses to Ethanol in C. elegans

Davies, A. G., Pierce-Shimomura, J. T., Kim, H., VanHoven, M. K., Thiele, T. R., Bonci, A., Bargmann, C. I., & McIntire, S. L. (2003) · Cell · doi:10.1016/s0092-8674(03)00979-6 · Cited by 359 · see citing works

Untitled work

(2006) · Cited by 336 · see citing works

Allelic and haplotypic association of <i>GABRA2</i> with alcohol dependence

Covault, J., Gelernter, J., Hesselbrock, V., Nellissery, M., & Kranzler, H. R. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30091 · Cited by 273 · cited 1× · see citing works

Linkage Disequilibrium at the ADH2 and ADH3 Loci and Risk of Alcoholism

Osier, M. V., PAKSTIS, A. J., Kidd, J. R., Lee, J.-F., Yin, S., Ko, H., Edenberg, H. J., Lu, R., & Kídd, K. K. (1999) · The American Journal of Human Genetics · doi:10.1086/302317 · Cited by 257 · see citing works

A twin study of genetic and environmental influences on tobacco initiation, regular tobacco use and nicotine dependence

MAES, H. H. M., Sullivan, P. F., Bulik, C. M., Neale, M. C., Prescott, C. A., Eaves, L. J., & Kendler, K. S. (2004) · Psychological Medicine · doi:10.1017/s0033291704002405 · Cited by 254 · see citing works

Psychiatric “diseases” versus behavioral disorders and degree of genetic influence

Bienvenu, O., Davydow, D., & Kendler, K. (2010) · Psychological Medicine · doi:10.1017/s003329171000084x · Cited by 244 · see citing works

Parental monitoring moderates the importance of genetic and environmental influences on adolescent smoking.

Dick, D. M., Viken, R. J., Purcell, S., Kaprio, J. A., Pulkkinen, L., & Rose, R. J. (2007) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.116.1.213 · Cited by 242 · see citing works

Polymorphism of ADH and ALDH Genes among Four Ethnic Groups in China and Effects upon the Risk for Alcoholism

Shen, Y., Fan, J.-H., Edenberg, H. J., Li, T., Cui, Y.-H., Wang, Y., Tian, C., Zhou, C., Zhou, R., Wang, J., et al. (1997) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-199710000-00017 · Cited by 242 · see citing works

SLO-1 Potassium Channels Control Quantal Content of Neurotransmitter Release at the C. elegans Neuromuscular Junction

Wang, Z.-W., Saifee, O., Nonet, M. L., & Salkoff, L. (2001) · Neuron · doi:10.1016/s0896-6273(01)00522-0 · Cited by 231 · see citing works

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

Spitz, M. R., Amos, C. I., Dong, Q., Lin, J. M., & Wu, X. (2008) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/djn363 · Cited by 229 · see citing works

The Role of GABRA2 in Risk for Conduct Disorder and Alcohol and Drug Dependence across Developmental Stages

Dick, D. M., Bierut, L., Hinrichs, A., Fox, L., Bucholz, K. K., Kramer, J., Kuperman, S., Hesselbrock, V., Schuckit, M., Almasy, L., et al. (2006) · Behavior Genetics · doi:10.1007/s10519-005-9041-8 · Cited by 227 · see citing works

Genetic and Environmental Predictors of Early Alcohol Use

Kaufman, J., Yang, B.-Z., Douglas-Palumberi, H., Crouse-Artus, M., Lipschitz, D., Krystal, J. H., & Gelernter, J. (2007) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.06.039 · Cited by 216 · see citing works

Interaction between CRHR1 gene and stressful life events predicts adolescent heavy alcohol use

Blomeyer, D., Treutlein, J., Esser, G., Schmidt, M. H., Schumann, G., & Laucht, M. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2007.04.026 · Cited by 211 · see citing works

Environmental Adversity Increases Genetic Risk for Externalizing Disorders

Hicks, B. M., South, S., Dirago, A. C., Iacono, W., & McGue, M. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2008.554 · Cited by 209 · see citing works

Tobacco Consumption in Swedish Twins Reared Apart and Reared Together

Kendler, K. S., Thornton, L. M., & Pedersen, N. L. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.9.886 · Cited by 207 · see citing works

The Self‐Rating of the Effects of Alcohol (SRE) form as a retrospective measure of the risk for alcoholism

Schuckit, M. A., Smith, T. L., & TIPP, J. E. (1997) · Addiction · doi:10.1111/j.1360-0443.1997.tb02977.x · Cited by 196 · see citing works

Association Between Alcoholism and ??-Amino Butyric Acid ??2 Receptor Subtype in a Russian Population

Lappalainen, J., Krupitsky, E. M., Remizov, M., Пчелина, С. Н., Taraskina, A., Zvartau, E. E., Somberg, L. K., Covault, J., Kranzler, H. R., Krystal, J. H., et al. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000158938.97464.90 · Cited by 192 · see citing works

Association of GABRA2 with drug dependence in the collaborative study of the genetics of alcoholism sample

Agrawal, A., Edenberg, H. J., Foroud, T., Bierut, L. J., Dunne, G., Hinrichs, A. L., Nurnberger, J. I., Crowe, R., Kuperman, S., Schuckit, M. A., et al. (2006) · Behavior Genetics · doi:10.1007/s10519-006-9069-4 · Cited by 189 · see citing works

Low Frequency of the ADH2*2 Allele among Atayal Natives of Taiwan with Alcohol Use Disorders

Thomasson, H. R., Crabb, D. W., Edenberg, H. J., Li, T., Hwu, H., Chen, C., Yeh, E., & Yin, S. (1994) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1994.tb00923.x · Cited by 182 · see citing works

Interactive Effects of the Serotonin Transporter 5-HTTLPR Polymorphism and Stressful Life Events on College Student Drinking and Drug Use

Covault, J., Tennen, H. A., Armeli, S., Conner, T. S., Herman, A. I., Cillessen, A. H. N., & Kranzler, H. R. (2006) · Biological Psychiatry · doi:10.1016/j.biopsych.2006.05.018 · Cited by 179 · see citing works

Exploring gene-environment interactions: Socioregional moderation of alcohol use.

Dick, D. M., Rose, R. J., Viken, R. J., Kaprio, J. A., & Koskenvuo, M. (2001) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.110.4.625 · Cited by 175 · see citing works

The Influence of Religion on Alcohol Use Initiation: Evidence for Genotype X Environment Interaction

Koopmans, J. R., Slutske, W. S., van Baal, G. C. M., & Boomsma, D. I. (1999) · Behavior Genetics · doi:10.1023/a:1021679005623 · Cited by 172 · see citing works

Acetylcholine Receptor (AChR) α5 Subunit Variant Associated with Risk for Nicotine Dependence and Lung Cancer Reduces (α4β2)2α5 AChR Function

Kuryatov, A., Berrettini, W., & Lindstrom, J. (2011) · Molecular Pharmacology · doi:10.1124/mol.110.066357 · Cited by 171 · see citing works

Role of GABRA2 in Trajectories of Externalizing Behavior Across Development and Evidence of Moderation by Parental Monitoring

Dick, D. M., Latendresse, S. J., Lansford, J. E., Budde, J., Goate, A., Dodge, K. A., Pettit, G. S., & Bates, J. E. (2009) · Archives of General Psychiatry · doi:10.1001/archgenpsychiatry.2009.48 · Cited by 164 · see citing works

A genetically modulated, intrinsic cingulate circuit supports human nicotine addiction

Hong, L. E., Hodgkinson, C. A., Yang, Y., Sampath, H., Ross, T. J., Buchholz, B., Salmeron, B. J., Srivastava, V., Thaker, G. K., Goldman, D. A., et al. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1004745107 · Cited by 164 · see citing works

Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

DeMeo, D. L., Mariani, T. J., Bhattacharya, S., Srisuma, S., Lange, C., Litonjua, A. A., Bueno, R., Pillai, S. G., Lomas, D. A., Sparrow, D., et al. (2009) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2009.09.004 · Cited by 162 · see citing works

Distinguishing Between Latent Classes and Continuous Factors with Categorical Outcomes: Class Invariance of Parameters of Factor Mixture Models

Lubke, G. H., & Neale, M. C. (2008) · Multivariate Behavioral Research · doi:10.1080/00273170802490673 · Cited by 161 · see citing works

A Risk Allele for Nicotine Dependence in CHRNA5 Is a Protective Allele for Cocaine Dependence

Grucza, R. A., Wang, J. C., Stitzel, J. A., Hinrichs, A. L., Saccone, S. F., Saccone, N. L., Bucholz, K. K., Cloninger, C. R., Neuman, R. J., Budde, J. P., et al. (2008) · Biological Psychiatry · doi:10.1016/j.biopsych.2008.04.018 · Cited by 152 · see citing works

Association between a 15q25 gene variant, smoking quantity and tobacco-related cancers among 17 000 individuals

Lips, E. H., Gaborieau, V., McKay, J. D., Chabrier, A., Hung, R. J., Boffetta, P., Hashibe, M., Zaridze, D., Szeszenia-Dabrowska, N., Lissowska, J., et al. (2010) · International Journal of Epidemiology · doi:10.1093/ije/dyp288 · Cited by 145 · see citing works

Creating a Social World

Kendler, K. S., Jacobson, K. C., Gardner, C. O., Gillespie, N. A., Aggen, S. A., & Prescott, C. A. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.8.958 · Cited by 127 · see citing works

Genomewide Association Analysis of Symptoms of Alcohol Dependence in the Molecular Genetics of Schizophrenia (MGS2) Control Sample: SYMPTOMS OF AD IN THE MGS2 CONTROL SAMPLE

Kendler, K. S., Kalsi, G., Holmans, P. A., Sanders, A. R., Aggen, S. H., Dick, D. M., Aliev, F., Shi, J., Levinson, D. F., & Gejman, P. V. (2011) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.2010.01427.x · Cited by 121 · see citing works

Factor and item‐response analysis DSM‐IV criteria for abuse of and dependence on cannabis, cocaine, hallucinogens, sedatives, stimulants and opioids

Gillespie, N. A., Neale, M. C., Prescott, C. A., Aggen, S. H., & Kendler, K. S. (2007) · Addiction · doi:10.1111/j.1360-0443.2007.01804.x · Cited by 112 · see citing works

Genome-wide association study of conduct disorder symptomatology

Dick, D. M., Aliev, F., Krueger, R. F., Edwards, A., Agrawal, A., Lynskey, M., Lin, P., Schuckit, M., Hesselbrock, V, Nurnberger, J., et al. (2011) · Molecular Psychiatry · doi:10.1038/mp.2010.73 · Cited by 111 · see citing works

Pathways to cannabis abuse: a multi‐stage model from cannabis availability, cannabis initiation and progression to abuse

Gillespie, N. A., Neale, M. C., & Kendler, K. S. (2009) · Addiction · doi:10.1111/j.1360-0443.2008.02456.x · Cited by 110 · see citing works

Dimensional anxiety mediates linkage of GABRA2 haplotypes with alcoholism

Enoch, M., Schwartz, L., Albaugh, B., Virkkunen, M. E., & Goldman, D. A. (2006) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30336 · Cited by 107 · see citing works

Trends in the Genetic Influences on Smoking

Boardman, J. D., Blalock, C. L., & Pampel, F. C. (2010) · Journal of Health and Social Behavior · doi:10.1177/0022146509361195 · Cited by 106 · see citing works

Marital status, alcohol dependence, and GABRA2: evidence for gene-environment correlation and interaction.

Dick, D. M., Arpana Agrawal, A., Schuckit, M. A., Bierut, L. J., Hinrichs, A. L., Fox, L. W., Mullaney, J., Cloninger, C. R., HESSELBROCK, V. M., Nürnberger, J. I., et al. (2006) · Journal of Studies on Alcohol · doi:10.15288/jsa.2006.67.185 · Cited by 106 · see citing works

Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence

Chen, X., Chen, J., Williamson, V. S., An, S., Hettema, J. M., Aggen, S. H., Neale, M. C., & Kendler, K. S. (2009) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30919 · Cited by 103 · see citing works

Rat supraoptic magnocellular neurones show distinct large conductance, Ca2+‐activated K+ channel subtypes in cell bodies versus nerve endings

Dopico, A. M., Widmer, H., Wang, G., Lémos, J. R., & Treistman, S. N. (1999) · The Journal of Physiology · doi:10.1111/j.1469-7793.1999.0101o.x · Cited by 97 · see citing works

Measurement of the risk for substance use disorders: phenotypic and genetic analysis of an index of common liability

Vanyukov, M. M., Kirisci, L., Moss, L., Tarter, R. E., Reynolds, M. D., Maher, B. S., Kirillova, G. P., Ridenour, T., & Clark, D. B. (2009) · Behavior Genetics · doi:10.1007/s10519-009-9269-9 · Cited by 88 · see citing works

Illicit drug use and abuse/dependence: modeling of two-stage variables using the CCC approach

Arpana Agrawal, A., Neale, M. C., Jacobson, K. C., Prescott, C. A., & Kendler, K. S. (2004) · Addictive Behaviors · doi:10.1016/j.addbeh.2004.09.007 · Cited by 86 · see citing works

The moderating effects of religiosity on the genetic and environmental determinants of smoking initiation.

Timberlake, D. S., Rhee, S., Haberstick, B. C., Hopfer, C., Ehringer, M. A., Lessem, J. M., Smolen, A., & Hewitt, J. (2006) · Nicotine & Tobacco Research · doi:10.1080/14622200500432054 · Cited by 82 · see citing works

Do Schools Moderate the Genetic Determinants of Smoking?

Boardman, J. D., Onge, J. M. S., Haberstick, B. C., Timberlake, D. S., & Hewitt, J. K. (2008) · Behavior Genetics · doi:10.1007/s10519-008-9197-0 · Cited by 80 · see citing works

Chromosome 15q25.1 genetic markers associated with level of response to alcohol in humans

Joslyn, G., Brush, G., Robertson, M. A., Smith, T. L., Kalmijn, J. A., Schuckit, M. A., & White, R. L. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0810970105 · Cited by 79 · see citing works

Mediating effects of smoking and chronic obstructive pulmonary disease on the relation between the CHRNA5‐A3 genetic locus and lung cancer risk

Wang, J., Spitz, M. R., Amos, C. I., Wilkinson, A. V., Wu, X., & Shete, S. S. (2010) · Cancer · doi:10.1002/cncr.25085 · Cited by 78 · see citing works

Nicotinic acetylcholine receptor genes on chromosome 15q25.1 are associated with nicotine and opioid dependence severity

Erlich, P. M., Hoffman, S. N., Rukstalis, M. R., Han, J., Chu, X., Kao, W. H. L., Gerhard, G. S., Stewart, W. F., & Boscarino, J. A. (2010) · Human Genetics · doi:10.1007/s00439-010-0876-6 · Cited by 66 · see citing works

Methodological issues in the assessment of substance use phenotypes

Neale, M. C., Aggen, S. H., MAES, H. H. M., Kubarych, T. S., & Schmitt, J. E. (2006) · Addictive Behaviors · doi:10.1016/j.addbeh.2006.03.047 · Cited by 57 · see citing works

Ethanol reduces excitability in a subgroup of primary sensory neurons by activation of BKCa channels

Gruß, M., Henrich, M., König, P., Hempelmann, G., Vogel, W., & Scholz, A. (2001) · European Journal of Neuroscience · doi:10.1046/j.0953-816x.2001.01754.x · Cited by 54 · see citing works

Measuring Addiction Propensity and Severity: The Need for a New Instrument

Conway, K., Levy, J., Vanyukov, M., Chandler, R. K., Rutter, J., Swan, G., & Neale, M. (2010) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2010.03.011 · Cited by 51 · see citing works

Family Transmission and Heritability of Externalizing Disorders: A Twin-Family Study

Hicks, B. M., Krueger, R. F., Iacono, W. G., McGue, M., & Patrick, C. J. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.9.922 · Cited by 46 · see citing works

Effects of Variation at theALDH2Locus on Alcohol Metabolism, Sensitivity, Consumption, and Dependence in Europeans

Dickson, P. A., James, M. R., Heath, A. C., Montgomery, G. W., Martin, N. G., Whitfield, J. B., & Birley, A. J. (2006) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2006.00128.x · Cited by 43 · see citing works

Fine mapping of chromosome 15q25.1 lung cancer susceptibility in African-Americans

Hansen, H. M., Xiao, Y., Rice, T., Bracci, P. M., Wrensch, M., Sison, J. D., Chang, J., Smirnov, I. V., Patoka, J., Seldin, M. F., et al. (2010) · Human Molecular Genetics · doi:10.1093/hmg/ddq268 · Cited by 40 · see citing works

Distinguishing Population Stratification from Genuine Allelic Effects with Mx: Association of ADH2 with Alcohol Consumption

Neale, M. C., Cherny, S. S., Sham, P. C., Whitfield, J. B., Heath, A. C., Birley, A. J., & Martin, N. G. (1999) · Behavior Genetics · doi:10.1023/a:1021638122693 · Cited by 29 · see citing works

A Twin Association Study of Nicotine Dependence with Markers in the CHRNA3 and CHRNA5 Genes

MAES, H. H. M., Neale, M. C., Chen, X., Chen, J., Prescott, C. A., & Kendler, K. S. (2011) · Behavior Genetics · doi:10.1007/s10519-011-9476-z · Cited by 22 · see citing works

Psychometric modeling of cannabis initiation and use and the symptoms of cannabis abuse, dependence and withdrawal in a sample of male and female twins

Gillespie, N. A., Kendler, K. S., & Neale, M. C. (2011) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2011.03.014 · Cited by 18 · see citing works

The behavioral economics of substance use disorders: reinforcement pathologies and their repair

Bickel, W. K., Johnson, M. W., Koffarnus, M. N., MacKillop, J., & Murphy, J. G. (2014) · Annual Review of Clinical Psychology · doi:10.1146/annurev-clinpsy-032813-153724 · Cited by 655 · see citing works

Time to connect: bringing social context into addiction neuroscience

Heilig, M., Epstein, D. H., Nader, M. A., & Shaham, Y. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.67 · Cited by 298 · see citing works

Assessment of culture and environment in the Adolescent Brain and Cognitive Development Study: Rationale, description of measures, and early data

Zucker, R. A., Gonzalez, R., Feldstein Ewing, S. W., Paulus, M. P., Arroyo, J., Fuligni, A., Morris, A. S., Sanchez, M., & Wills, T. (2018) · Developmental Cognitive Neuroscience · doi:10.1016/j.dcn.2018.03.004 · Cited by 221 · see citing works

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders

Hatoum, A. S., Colbert, S. M. C., Johnson, E. C., Huggett, S. B., Deak, J. D., Pathak, G. A., Jennings, M. V., Paul, S. E., Karcher, N. R., Hansen, I., et al. (2023) · Nature Mental Health · doi:10.1038/s44220-023-00034-y · Cited by 241 · see citing works

The brain disease model of addiction: is it supported by the evidence and has it delivered on its promises?

Hall, W., Carter, A., & Forlini, C. (2015) · The Lancet Psychiatry · doi:10.1016/s2215-0366(14)00126-6 · Cited by 233 · see citing works

A Targeted Review of the Neurobiology and Genetics of Behavioural Addictions: An Emerging Area of Research

Leeman, R. F., & Potenza, M. N. (2013) · The Canadian Journal of Psychiatry · doi:10.1177/070674371305800503 · Cited by 235 · see citing works

Overview of the Genetics of Alcohol Use Disorder

Tawa, E. A., Hall, S. D., & Lohoff, F. W. (2016) · Alcohol and Alcoholism · doi:10.1093/alcalc/agw046 · Cited by 181 · see citing works

Striatal ups and downs: Their roles in vulnerability to addictions in humans

Leyton, M., & Vezina, P. (2013) · Neuroscience &amp; Biobehavioral Reviews · doi:10.1016/j.neubiorev.2013.01.018 · Cited by 165 · see citing works

Personality traits and vulnerability or resilience to substance use disorders

Belcher, A. M., Volkow, N. D., Moeller, F. G., & Ferré, S. (2014) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2014.01.010 · Cited by 162 · see citing works

Shared Genetic Vulnerability for Disordered Gambling and Alcohol Use Disorder in Men and Women: Evidence from a National Community-Based Australian Twin Study

Slutske, W. S., Ellingson, J. M., Richmond‐Rakerd, L. S., Zhu, G., & Martin, N. G. (2013) · Twin Research and Human Genetics · doi:10.1017/thg.2013.11 · Cited by 125 · see citing works

Extended Heroin Access Increases Heroin Choices Over a Potent Nondrug Alternative

Lenoir, M., Cantin, L., Vanhille, N., Serre, F., & Ahmed, S. H. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.17 · Cited by 114 · see citing works

Marijuana use trends among college students in states with and without legalization of recreational use: initial and longer‐term changes from 2008 to 2018

Bae, H. T., & Kerr, D. (2019) · Addiction · doi:10.1111/add.14939 · Cited by 106 · see citing works

Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement

Carey, C. E., Arpana Agrawal, A., Bucholz, K. K., Hartz, S. M., Lynskey, M. T., Nelson, E. C., Bierut, L. J., & Bogdan, R. (2016) · Frontiers in Genetics · doi:10.3389/fgene.2016.00149 · Cited by 103 · see citing works

DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence

Cecil, C. A. M., Walton, E., Smith, R. G., Viding, E., McCrory, E. J., Relton, C. L., Suderman, M., Pingault, J.-B., McArdle, W., Gaunt, T. R., et al. (2016) · Translational Psychiatry · doi:10.1038/tp.2016.247 · Cited by 101 · see citing works

A Primer on the Genetics of Comorbid Eating Disorders and Substance Use Disorders

Munn‐Chernoff, M. A., & Baker, J. H. (2015) · European Eating Disorders Review · doi:10.1002/erv.2424 · Cited by 97 · see citing works

The genetics of alcohol dependence

Rietschel, M., & Treutlein, J. (2012) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2012.06794.x · Cited by 95 · see citing works

Classification and psychopathology research.

Berenbaum, H. (2013) · Journal of Abnormal Psychology · doi:10.1037/a0033096 · Cited by 91 · see citing works

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H. J., Nurnberger, J. I., et al. (2017) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.2269 · Cited by 90 · see citing works

Trying to make sense of rodents' drug choice behavior

Ahmed, S. H. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.09.027 · Cited by 74 · see citing works

Shaping vulnerability to addiction – the contribution of behavior, neural circuits and molecular mechanisms

Egervári, G., Ciccocioppo, R., Jentsch, J. D., & Hurd, Y. L. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.05.019 · Cited by 75 · see citing works

Adolescent substance use behavior and suicidal behavior for boys and girls: a cross-sectional study by latent analysis approach

Wang, P., & Yen, C. (2017) · BMC Psychiatry · doi:10.1186/s12888-017-1546-1 · Cited by 63 · see citing works

The role of the BK channel in ethanol response behaviors: evidence from model organism and human studies

Bettinger, J. C., & Davies, A. G. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00346 · Cited by 61 · see citing works

Substance Use and Substance Use Disorders

Chassin, L., Colder, C. R., Hussong, A. M., & Sher, K. J. (2016) · Wiley eBooks · doi:10.1002/9781119125556.devpsy319 · Cited by 58 · see citing works

The Genetically Informed Neurobiology of Addiction (GINA) model

Bogdan, R., Hatoum, A. S., Johnson, E. C., & Arpana Agrawal, A. (2022) · Nature reviews. Neuroscience · doi:10.1038/s41583-022-00656-8 · Cited by 54 · see citing works

Cocaine addiction as a homeostatic reinforcement learning disorder.

Keramati, M., Durand, A., Girardeau, P., Gutkin, B., & Ahmed, S. H. (2017) · Psychological Review · doi:10.1037/rev0000046 · Cited by 44 · see citing works

ADHD co-morbidities: A review of implication of gene × environment effects with dopamine-related genes

Kanarik, M., Grimm, O., Mota, N. R., Reif, A., & Harro, J. (2022) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2022.104757 · Cited by 48 · see citing works

Cannabis and amphetamine use and its psychosocial correlates among school-going adolescents in Ghana

Asante, K. O. (2019) · Child and Adolescent Psychiatry and Mental Health · doi:10.1186/s13034-019-0293-0 · Cited by 47 · see citing works

Genetic influences on hormonal markers of chronic hypothalamic–pituitary–adrenal function in human hair

Tucker–Drob, E. M., Grotzinger, A. D., Briley, D. A., Engelhardt, L. E., Mann, F. D., Patterson, M. W., Kirschbaum, C., Adam, E. K., Church, J. A., Tackett, J. L., et al. (2017) · Psychological Medicine · doi:10.1017/s0033291716003068 · Cited by 45 · see citing works

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol‐Response Behaviors in Model Organisms

Adkins, A. E., Hack, L. M., Bigdeli, T. B., Williamson, V. S., McMichael, G. O., Mamdani, M., Edwards, A. C., Alıev, F., Chan, R. F., Bhandari, P., et al. (2017) · Alcoholism Clinical and Experimental Research · doi:10.1111/acer.13362 · Cited by 44 · see citing works

An epigenetic, transgenerational model of increased mental health disorders in children, adolescents and young adults

Monaco, A. P. (2020) · European Journal of Human Genetics · doi:10.1038/s41431-020-00726-4 · Cited by 45 · see citing works

Genetic and Environmental Interplay in Adolescent Substance Use Disorders

Hines, L. A., Morley, K. I., Mackie, C. J., & Lynskey, M. T. (2015) · Current Addiction Reports · doi:10.1007/s40429-015-0049-8 · Cited by 42 · see citing works

Building causal knowledge in behavior genetics

Madole, J. W., & Harden, K. P. (2022) · Behavioral and Brain Sciences · doi:10.1017/s0140525x22000681 · Cited by 42 · see citing works

Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disordersPreprint

Hatoum, A. S., Colbert, S. M. C., Johnson, E. C., Huggett, S. B., Deak, J. D., Pathak, G. A., Jennings, M. V., Paul, S. E., Karcher, N. R., Hansen, I. S., et al. (2022) · medRxiv · doi:10.1101/2022.01.06.22268753 · Cited by 42 · see citing works

Fischer 344 and Lewis Rat Strains as a Model of Genetic Vulnerability to Drug Addiction

Cadoni, C. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00013 · Cited by 41 · see citing works

Individual decision-making in the causal pathway to addiction: contributions and limitations of rodent models

Ahmed, S. H. (2018) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2017.07.005 · Cited by 39 · see citing works

SWI/SNF chromatin remodeling regulates alcohol response behaviors in Caenorhabditis elegans and is associated with alcohol dependence in humans

Mathies, L. D., Blackwell, G. G., Austin, M. K., Edwards, A. C., Riley, B. P., Davies, A. G., & Bettinger, J. C. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413451112 · Cited by 37 · see citing works

Review: Genetic research on alcohol use outcomes in African American populations: A review of the literature, associated challenges, and implications

Dick, D. M., Barr, P. B., Guy, M. C., Nasim, A., & Scott, D. M. (2017) · American Journal on Addictions · doi:10.1111/ajad.12495 · Cited by 37 · see citing works

Genetic and Environmental Variation in Continuous Phenotypes in the ABCD Study®

Maes, H., Lapato, D. M., Schmitt, J., Luciana, M., Banich, M., Bjork, J., Hewitt, J., Madden, P., Heath, A., Barch, D., et al. (2022) · Behavior Genetics · doi:10.1007/s10519-022-10123-w · Cited by 37 · see citing works

Genetic Factors Control Nicotine Self-Administration in Isogenic Adolescent Rat Strains

Chen, H., Hiler, K. A., Tolley, E. A., Matta, S. G., & Sharp, B. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0044234 · Cited by 35 · see citing works

Parent and peer influences on emerging adult substance use disorder: A genetically informed study

Bountress, K. E., Chassin, L., & Lemery‐Chalfant, K. (2016) · Development and Psychopathology · doi:10.1017/s095457941500125x · Cited by 32 · see citing works

Denise Kandel's classic work on the gateway sequence of drug acquisition

Lynskey, M. T., & Arpana Agrawal, A. (2018) · Addiction · doi:10.1111/add.14190 · Cited by 32 · see citing works

The Relationships of Parental Alcohol Versus Tobacco and Marijuana Use With Early Adolescent Onset of Alcohol Use

Capaldi, D. M., Tiberio, S. S., Kerr, D., & Pears, K. C. (2016) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2016.77.95 · Cited by 32 · see citing works

Genetic basis of delay discounting in frequent gamblers: examination of a priori candidates and exploration of a panel of dopamine‐related loci

Gray, J. C., & MacKillop, J. (2014) · Brain and Behavior · doi:10.1002/brb3.284 · Cited by 31 · see citing works

Consensus paper of the WFSBP task force on biological markers: Biological markers for alcoholism

Hashimoto, E., Riederer, P. F., HESSELBROCK, V. M., Hesselbrock, M. N., Mann, K. F., Ukai, W., Sohma, H., Thibaut, F., Schuckit, M. A., & Saito, T. (2013) · The World Journal of Biological Psychiatry · doi:10.3109/15622975.2013.838302 · Cited by 32 · see citing works

Prospective Prediction of First Onset of Nonsuicidal Self-Injury in Adolescent Girls

Gromatsky, M. A., He, S., Perlman, G., Klein, D. N., Kotov, R., & Waszczuk, M. A. (2019) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1016/j.jaac.2019.08.006 · Cited by 31 · see citing works

Let’s agree to agree: a comment on Hogarth (2020), with a plea for not-so-competing theories of addiction

Epstein, D. H. (2020) · Neuropsychopharmacology · doi:10.1038/s41386-020-0618-y · Cited by 31 · see citing works

Treatment of Adolescent Substance Use Disorders and Co-Occurring Internalizing Disorders: A Critical Review and Proposed Model

A. Hulvershorn, L., D. Quinn, P., & L. Scott, E. (2015) · Current Drug Abuse Reviews · doi:10.2174/1874473708666150514102745 · Cited by 30 · see citing works

The role of genetics in stress effects on health and addiction

Buchanan, T. W., & Lovallo, W. R. (2018) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2018.09.005 · Cited by 30 · see citing works

Personality and Personality Disorders in Medication-Overuse Headache: A Controlled Study by SWAP-200

Galli, F., Tanzilli, A., Simonelli, A., Tassorelli, C., Sances, G., Parolin, M., Cristofalo, P., Gualco, I., & Lingiardi, V. (2019) · Pain Research and Management · doi:10.1155/2019/1874078 · Cited by 28 · see citing works

Maternal substance use in pregnancy: Differential prediction by childhood adversity subtypes

Racine, N. M., McDonald, S., Chaput, K. H., Tough, S., & Madigan, S. L. (2020) · Preventive Medicine · doi:10.1016/j.ypmed.2020.106303 · Cited by 27 · see citing works

Dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder

Groenman, A. P., Greven, C. U., van Donkelaar, M. M. J., Schellekens, A., van Hulzen, K. J. E., Rommelse, N. N. J., Hartman, C. A., Hoekstra, P. J., Luman, M., Franke, B., et al. (2015) · Addiction Biology · doi:10.1111/adb.12230 · Cited by 27 · see citing works

The mathematical limits of genetic prediction for complex chronic disease

Keyes, K. M., Smith, G. D., Koenen, K. C., & Galea, S. (2015) · Journal of Epidemiology & Community Health · doi:10.1136/jech-2014-204983 · Cited by 26 · see citing works

Onset of Alcohol Use Disorders and Comorbid Psychiatric Disorders in a Military Cohort: Are there Critical Periods for Prevention of Alcohol Use Disorders?

Fink, D. S., Gallaway, M. S., Tamburrino, M., Liberzon, I., Chan, P., Cohen, G. H., Sampson, L., Shirley, E. R., Goto, T., D’Arcangelo, N., et al. (2015) · Prevention Science · doi:10.1007/s11121-015-0624-1 · Cited by 25 · see citing works

Interleukin 4 gene polymorphism (−589C/T) and the risk of asthma: a meta-analysis and met-regression based on 55 studies

Kousha, A., Gorabi, A. M., Forouzesh, M., Hosseini, M., Alexander, M., Imani, D., Razi, B., Mousavi, M. J., Aslani, S., & Mikaeili, H. (2020) · BMC Immunology · doi:10.1186/s12865-020-00384-7 · Cited by 28 · see citing works

Association between polygenic risk for tobacco or alcohol consumption and liability to licit and illicit substance use in young Australian adults

Chang, L.-H., Couvy‐Duchesne, B., Liu, M., Medland, S. E., Verhulst, B., Benotsch, E. G., Hickie, I. B., Martin, N. G., & Gillespie, N. A. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.01.015 · Cited by 23 · see citing works

A Concept Analysis of Substance Misuse to Inform Contemporary Terminology

Mahmoud, K. F., Finnell, D. S., Savage, C. L., Puskar, K. R., & Mitchell, A. M. (2017) · Archives of Psychiatric Nursing · doi:10.1016/j.apnu.2017.06.004 · Cited by 24 · see citing works

Role of placebo effects in pain and neuropsychiatric disorders

Belcher, A. M., Ferré, S., Martinez, P. E., & Colloca, L. (2017) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2017.06.003 · Cited by 23 · see citing works

From Genes to Treatments: A Systematic Review of the Pharmacogenetics in Smoking Cessation

Salloum, N. C., Buchalter, E. L. F., Chanani, S., Espejo, G. D., Ismail, M. S., Laine, R. O., Nageeb, M., Srivastava, A. B., Trapp, N. T., Trillo, L., et al. (2018) · Pharmacogenomics · doi:10.2217/pgs-2018-0023 · Cited by 23 · see citing works

The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings

Saccone, N. L., Baurley, J. W., Bergen, A. W., David, S. P., Elliott, H. R., Foreman, M. G., Kaprio, J. A., Piasecki, T. M., Relton, C. L., Zawertailo, L. A., et al. (2017) · Nicotine & Tobacco Research · doi:10.1093/ntr/ntx096 · Cited by 23 · see citing works

Exposure to Maternal Smoking During Pregnancy as a Risk Factor for Tobacco Use in Adult Offspring

Rydell, M., Magnusson, C., Cnattingius, S., Granath, F. N., Svensson, A. C., & Galanti, M. R. (2014) · American Journal of Epidemiology · doi:10.1093/aje/kwu074 · Cited by 23 · see citing works

DNA Methylation, Substance Use and Addiction: a Systematic Review of Recent Animal and Human Research from a Developmental Perspective

Cecil, C. A. M., Walton, E., & Viding, E. M. (2015) · Current Addiction Reports · doi:10.1007/s40429-015-0072-9 · Cited by 22 · see citing works

Associations between polygenic risk for tobacco and alcohol use and liability to tobacco and alcohol use, and psychiatric disorders in an independent sample of 13,999 Australian adults

Chang, L.-H., Whitfield, J. B., Liu, M., Medland, S. E., Hickie, I. B., Martin, N. G., Verhulst, B., Heath, A. C., Madden, P. A. F., Statham, D. J., et al. (2019) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2019.107704 · Cited by 19 · see citing works

A review of the genetic basis of problematic Internet use

Werling, A. M., & Grünblatt, E. (2022) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2022.101149 · Cited by 21 · see citing works

Gene–Environment Correlation in Humans: Lessons from Psychology for Quantitative Genetics

Saltz, J. B. (2019) · Journal of Heredity · doi:10.1093/jhered/esz027 · Cited by 21 · see citing works

Evaluating the Validity of Caffeine Use Disorder

Budney, A. J., Lee, D. C., & Juliano, L. M. (2015) · Current Psychiatry Reports · doi:10.1007/s11920-015-0611-z · Cited by 20 · see citing works

Narrative review of genes, environment, and cigarettes

Do, E. K., & MAES, H. H. M. (2016) · Annals of Medicine · doi:10.1080/07853890.2016.1177196 · Cited by 19 · see citing works

Social Determinants of Inter-Individual Variability and Vulnerability: The Role of Dopamine

Fauré, P., Fayad, S. L., Solié, C., & Reynolds, L. M. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2022.836343 · Cited by 17 · see citing works

Attention deficit hyperactivity disorder and substance abuse: An investigation in young Austrian males

Riegler, A., Völkl-Kernstock, S., Lesch, O., Walter, H., & Skala, K. (2017) · Journal of Affective Disorders · doi:10.1016/j.jad.2017.03.072 · Cited by 20 · see citing works

Substance-Related and Addictive Disorders

(2022) · American Psychiatric Association Publishing eBooks · doi:10.1176/appi.books.9780890425787.x16_substance_related_disorders · Cited by 20 · see citing works

In-utero exposure to maternal smoking is not linked to tobacco use in adulthood after controlling for genetic and family influences: a Swedish sibling study

Rosenqvist, M. A., Granath, F. N., Cnattingius, S., Magnusson, C., & Galanti, M. R. (2014) · European Journal of Epidemiology · doi:10.1007/s10654-014-9912-5 · Cited by 17 · see citing works

Intergenerational continuity in parents’ and adolescents’ externalizing problems: The role of life events and their interaction with GABRA2.

Salvatore, J. E., Meyers, J. L., Yan, J., Aliev, F., Lansford, J. E., Pettit, G. S., Bates, J. E., Dodge, K. A., Rose, R. J., Pulkkinen, L., et al. (2015) · Journal of Abnormal Psychology · doi:10.1037/abn0000066 · Cited by 17 · see citing works

Psychosocial interventions for substance-abusing parents and their young children: A scoping review

Heimdahl, K., & Karlsson, P. (2016) · Addiction Research & Theory · doi:10.3109/16066359.2015.1118064 · Cited by 17 · see citing works

Genetic and environmental risk factors in the non‐medical use of over‐the‐counter or prescribed analgesics, and their relationship to major classes of licit and illicit substance use and misuse in a population‐based sample of young adult twins

Gillespie, N. A., Bates, T. C., Hickie, I. B., Medland, S. E., Verhulst, B., Kirkpatrick, R. M., Kendler, K. S., Martin, N. G., & Benotsch, E. G. (2019) · Addiction · doi:10.1111/add.14750 · Cited by 17 · see citing works

Problem-Oriented Screening Instrument for Teenagers

Rahdert, E. R. (1992) · PsycTESTS Dataset · doi:10.1037/t04795-000 · Cited by 17 · see citing works

Early Predictors of Trajectories of Tobacco Use Level from Adolescence to Young Adulthood: A 16-Year Follow-Up of the TEMPO Cohort Study (1999–2015)

Clergue‐Duval, V., Mary‐Krause, M., Bolze, C., Fombonne, E. J., & Melchior, M. (2018) · European Addiction Research · doi:10.1159/000495759 · Cited by 16 · see citing works

National Institute on Drug Abuse genomics consortium white paper: Coordinating efforts between human and animal addiction studies

Cates, H. M., Benca‐Bachman, C. E., de Guglielmo, G., Schoenrock, S. A., Shu, C., & Kallupi, M. (2019) · Genes Brain & Behavior · doi:10.1111/gbb.12577 · Cited by 13 · see citing works

Passive Smoking Increases the Risk for Intestinal Surgeries in Patients With Crohn’s Disease

Scharrer-Cabello, S. I., Lissner, D., Primas, C., Reinisch, W., Novacek, G., Reinisch, S., Papay, P., Dejaco, C., Vogelsang, H., & Miehsler, W. (2020) · Inflammatory Bowel Diseases · doi:10.1093/ibd/izaa117 · Cited by 14 · see citing works

Cdh13 and AdipoQ gene knockout alter instrumental and Pavlovian drug conditioning

King, C. P., Militello, L., Hart, A., Pierre, C. L. S., Leung, E., Versaggi, C. L., Roberson, N., Catlin, J. P., Palmer, A. A., Richards, J. B., et al. (2017) · Genes, Brain and Behavior · doi:10.1111/gbb.12382 · Cited by 15 · see citing works

Sex differences in genetic and environmental contributions to alcohol consumption from early adolescence to young adulthood

Seglem, K. B., Waaktaar, T., Ask, H., & Torgersen, S. O. (2016) · Addiction · doi:10.1111/add.13321 · Cited by 13 · see citing works

Polygenic Risk for Externalizing Psychopathology and Executive Dysfunction in Trauma-Exposed Veterans

Sadeh, N., Wolf, E. J., Logue, M. W., Lusk, J., Hayes, J. P., McGlinchey, R. E., Milberg, W., Stone, A., Schichman, S. A., & Miller, M. W. (2015) · Clinical Psychological Science · doi:10.1177/2167702615613310 · Cited by 13 · see citing works

Identifying risk factors involved in the common versus specific liabilities to substance use: A genetically informed approach

Iob, E., Schoeler, T., Cecil, C. A. M., Walton, E., McQuillin, A., & Pingault, J. (2020) · Addiction Biology · doi:10.1111/adb.12944 · Cited by 11 · see citing works

Cannabis Use Disorders

Duncan, P. M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781139025515.013 · Cited by 12 · see citing works

Beyond the factor indeterminacy problem using genome-wide association data

Sullivan, M. L. C., Schwaba, T., Harden, K. P., Grotzinger, A. D., Nivard, M. G., & Tucker–Drob, E. M. (2024) · Nature Human Behaviour · doi:10.1038/s41562-023-01789-1 · Cited by 11 · see citing works

Genome wide analysis of rare copy number variations in alcohol abuse or dependence

Rodríguez-López, J., Flórez, G., Blanco, V., Pereiro, C., Fernández, J. M., Fariñas, E., Estévez, V., Gómez-Trigo, J., Gurriarán, X., Calvo, R. C., et al. (2018) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2018.06.001 · Cited by 11 · see citing works

Explaining Individual Differences in Alcohol Intake in Adults: Evidence for Genetic and Cultural Transmission?

van Beek, J. H. D. A., de Moor, M. H. M., Geels, L. M., Willemsen, G. A. H. M., & Boomsma, D. I. (2014) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2014.75.201 · Cited by 11 · see citing works

Drugs of Abuse Induced-Subversion of the Peripheral Immune Response and Central Glial Activity: Focus on Novel Therapeutic Approaches

Magrone, T., & Jirillo, E. (2018) · Endocrine Metabolic & Immune Disorders - Drug Targets · doi:10.2174/1871530319666181129104329 · Cited by 11 · see citing works

Association between polygenic liability for schizophrenia and substance involvement: A nationwide population‐based study in Taiwan

Wang, S., Lai, R., Lee, Y., Su, M., Chen, C., Hsiao, P., Yang, A. C., Liu, Y., Tsai, S., & Kuo, P. (2020) · Genes Brain & Behavior · doi:10.1111/gbb.12639 · Cited by 11 · see citing works

Developmental Changes in Genetic and Shared Environmental Contributions to Smoking Initiation and Subsequent Smoking Quantity in Adolescence and Young Adulthood

Bares, C. B., Kendler, K. S., & MAES, H. H. M. (2015) · Twin Research and Human Genetics · doi:10.1017/thg.2015.48 · Cited by 11 · see citing works

Protection Genes in Nucleus Accumbens Shell Affect Vulnerability to Nicotine Self-Administration across Isogenic Strains of Adolescent Rat

Chen, H., Luo, R., Gong, S., Matta, S. G., & Sharp, B. M. (2014) · PLoS ONE · doi:10.1371/journal.pone.0086214 · Cited by 11 · see citing works

The Genetic and Environmental Association Between Parental Monitoring and Risk of Cannabis, Stimulants, and Cocaine Initiation in a Sample of Male Twins: Does Parenting Matter?

Olivares, E. L., Kendler, K. S., Neale, M. C., & Gillespie, N. A. (2016) · Twin Research and Human Genetics · doi:10.1017/thg.2016.52 · Cited by 11 · see citing works

Maternal smoking during pregnancy and offspring’s tobacco dependence. A study of exposure-discordant sibling pairs

Rydell, M., Granath, F., Cnattingius, S., Svensson, A. C., Magnusson, C., & Galanti, M. R. (2016) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2016.07.030 · Cited by 11 · see citing works

Voltage-Sensitive Potassium Channels of the BK Type and Their Coding Genes Are Alcohol Targets in Neurons

Dopico, A. M., Bukiya, A. N., & Bettinger, J. C. (2017) · Handbook of experimental pharmacology · doi:10.1007/164_2017_78 · Cited by 11 · see citing works

Role of genetic background in the effects of adolescent nicotine exposure on mesolimbic dopamine transmission

Cadoni, C., De Felice, M., Corongiu, S., Dessì, C., Espa, E., Melis, M., & Fenu, S. (2020) · Addiction Biology · doi:10.1111/adb.12803 · Cited by 10 · see citing works

Socioeconomic Status and Adolescent Alcohol Involvement: Evidence for a Gene–Environment Interaction

Davis, C. N., & Slutske, W. S. (2018) · Journal of Studies on Alcohol and Drugs · doi:10.15288/jsad.2018.79.725 · Cited by 10 · see citing works

Determining the stability of genome-wide factors in BMI between ages 40 to 69 years

Gillespie, N. A., Gentry, A. E., Kirkpatrick, R. M., MAES, H. H. M., Reynolds, C. A., Mathur, R., Kendler, K. S., Peterson, R. E., & Webb, B. T. (2022) · PLoS Genetics · doi:10.1371/journal.pgen.1010303 · Cited by 9 · see citing works

CHRNA5 rs16969968 and CHRNA3 rs578776 polymorphisms are associated with multiple nicotine dependence phenotypes in Bangladeshi smokers

Chaity, N. I., & Apu, M. N. H. (2022) · Heliyon · doi:10.1016/j.heliyon.2022.e09947 · Cited by 8 · see citing works

Anticipating possible policy uses of addiction neuroscience research

Hall, W., & Carter, A. (2013) · Drugs Education Prevention and Policy · doi:10.3109/09687637.2013.779426 · Cited by 8 · see citing works

Effects of Fathers on Adolescent Daughters’ Frequency of Substance Use and Risky Sexual Behavior

DelPriore, D. J., Brener, S. A., Hill, S. E., & Ellis, B. J. (2020) · Journal of Research on Adolescence · doi:10.1111/jora.12589 · Cited by 8 · see citing works

Heart rate, serotonin transporter linked polymorphic region (5-HTTLPR) genotype, and violence in an incarcerated sample

Armstrong, T. A., Boisvert, D. L., Flores, S., Symonds, M., & Gangitano, D. A. (2017) · Journal of Criminal Justice · doi:10.1016/j.jcrimjus.2017.05.012 · Cited by 7 · see citing works

Re-socializing the Vulnerable Brain: Building an Ethically Sustainable Brain Disease Model of Addiction

Kuorikoski, J., & Uusitalo, S. (2018) · Frontiers in Sociology · doi:10.3389/fsoc.2018.00039 · Cited by 7 · see citing works

Genetics of substance use disorders: a review

Deak, J. D., & Johnson, E. C. (2021) · Psychological Medicine · doi:10.1017/s0033291721000969 · Cited by 187 · see citing works

The genetic epidemiology of substance use disorder: A review

Prom‐Wormley, E. C., Ebejer, J. L., Dick, D. M., & Bowers, M. S. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.06.040 · Cited by 173 · see citing works

Molecular genetics of substance use disorders: An umbrella review

López‐León, S., González‐Giraldo, Y., Wegman-Ostrosky, T., & Forero, D. A. (2021) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2021.01.019 · Cited by 61 · see citing works

Advancing substance use disorder biology by studying underlying gene x environment interactions

Sidamon‐Eristoff, A. E., Rivera-Hernández, M., Huckins, L. M., Montalvo‐Ortiz, J. L., & Brennand, K. (2026) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2026.102443 · Cited by 1 · see citing works

Genetics of Substance Use Disorders

Goldman, D. A., & Sambo, D. O. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780197640654.003.0045