Hypoxia — a key regulatory factor in tumour growth

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Items 101–167 of 167

1. Development and analysis of multi-layer scaffolds for tissue engineering
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2. The tumour hypoxia induced non-coding transcriptome
   Choudhry, Hani, Harris, Adrian L., McIntyre, Alan · 2016 · Molecular Aspects of Medicine
3. Enhancement of Hypoxia-Induced Tumor Cell Death <b> <i>In vitro</i> </b> and Radiation Therapy <b> <i>In vivo</i> </b> by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α
   Zhang, Xiuwu, Kon, Takashi, Wang, He, Li, Fang, Huang, Qian, Rabbani, Zahid N., Kirkpatrick, John P., Vujaskovic, Zeljko, Dewhirst, Mark W., Li, Chuan-Yuan · 2004 · Cancer Research
4. Hypoxia signaling in cancer: Implications for therapeutic interventions
   Zhuang, Yan, Liu, Kua, He, Qinyu, Gu, Xiaosong, Jiang, Chunping, Wu, Junhua · 2023 · MedComm
5. HIF inhibitor 32-134D eradicates murine hepatocellular carcinoma in combination with anti-PD1 therapy
   Salman, Shaima, Meyers, David J., Wicks, Elizabeth E., Lee, Sophia N., Datan, Emmanuel, Thomas, Aline M., Anders, Nicole M., Hwang, Yousang, Lyu, Yajing, Yang, Yongkang et al. · 2022 · Journal of Clinical Investigation
6. High Intensity Focused Ultrasound-Responsive and Ultrastable Cerasomal Perfluorocarbon Nanodroplets for Alleviating Tumor Multidrug Resistance and Epithelial–Mesenchymal Transition
   Ma, Xiaotu, Yao, Meinan, Shi, Jiyun, Li, Xiaoda, Gao, Yu, Luo, Qi, Hou, Rui, Liang, Xiaolong, Wang, Fan · 2020 · ACS Nano
7. Oncogenic KRAS modulates mitochondrial metabolism in human colon cancer cells by inducing HIF-1α and HIF-2α target genes
   Chun, Sang Y, Johnson, Craig, Washburn, Joseph G, Cruz-Correa, Marcia R, Dang, Duyen T, Dang, Long H · 2010 · Molecular Cancer
8. Proteasomal Inhibition Attenuates Transcriptional Activity of Hypoxia-Inducible Factor 1 (HIF-1) via Specific Effect on the HIF-1α C-Terminal Activation Domain
   Kaluz, Stefan, Kaluzová, Milota, Stanbridge, Eric J. · 2006 · Molecular and Cellular Biology
9. HINCUTs in cancer: Hypoxia-induced noncoding ultraconserved transcripts
   Ferdin, J, Nishida, N, Wu, X, Nicoloso, M S, Shah, M Y, Devlin, C, Ling, H, Shimizu, M, Kumar, K, Cortez, M A et al. · 2013 · Cell Death &amp; Differentiation
10. Mechanisms of Hypoxic Gene Regulation of Angiogenesis Factor Cyr61 in Melanoma Cells
    Kunz, Manfred, Moeller, Steffen, Koczan, Dirk, Lorenz, Peter, Wenger, Roland H., Glocker, Michael O., Thiesen, Hans-Juergen, Gross, Gerd, Ibrahim, Saleh M. · 2003 · Journal of Biological Chemistry
11. Tumor vasculature normalization by orally fed erlotinib to modulate the tumor microenvironment for enhanced cancer nanomedicine and immunotherapy
    Chen, Qian, Xu, Ligeng, Chen, Jiawen, Yang, Zhijuan, Liang, Chao, Yang, Yu, Liu, Zhuang · 2017 · Biomaterials
12. Target gene selectivity of hypoxia-inducible factor-α in renal cancer cells is conveyed by post-DNA-binding mechanisms
    Lau, K W, Tian, Y-M, Raval, R R, Ratcliffe, P J, Pugh, C W · 2007 · British Journal of Cancer
13. Hypoxia-inducible factor 1α-induced epithelial–mesenchymal transition of endometrial epithelial cells may contribute to the development of endometriosis
    Xiong, Yao, Liu, Yi, Xiong, Wenqian, Zhang, Ling, Liu, Hengwei, Du, Yu, Li, Na · 2016 · Human Reproduction
14. Hypoxia-inducible Factor 1α and Antiangiogenic Activity of Farnesyltransferase Inhibitor SCH66336 in Human Aerodigestive Tract Cancer
    Han, Ji-Youn, Oh, Seung Hyun, Morgillo, Floriana, Myers, Jeffrey N., Kim, Edward, Hong, Waun Ki, Lee, Ho-Young · 2005 · JNCI: Journal of the National Cancer Institute
15. Poly(ethylene glycol)-b-poly (lysine) copolymer bearing nitroaromatics for hypoxia-sensitive drug delivery
    Thambi, Thavasyappan, Son, Soyoung, Lee, Doo Sung, Park, Jae Hyung · 2016 · Acta Biomaterialia
16. Normoxic stabilization of hypoxia-inducible factor-1α by modulation of the labile iron pool in differentiating U937 macrophages: effect of natural resistance-associated macrophage protein 1
    Knowles, Helen J., Mole, David R., Ratcliffe, Peter J., Harris, Adrian L. · 2006 · Cancer Research
17. Cell Volume Regulation in Epithelial Physiology and Cancer
    Pedersen, Stine F., Hoffmann, Else K., Novak, Ivana · 2013 · Frontiers in Physiology
18. Metal peroxides for cancer treatment
    He, Jin, Fu, Lian-Hua, Qi, Chao, Lin, Jing, Huang, Peng · 2021 · Bioactive Materials
19. Growth Factor-Mediated Induction of HDM2 Positively Regulates Hypoxia-Inducible Factor 1α Expression
    Bárdos, Julia I., Chau, Noan-Minh, Ashcroft, Margaret · 2004 · Molecular and Cellular Biology
20. A 3D microvascular network model to study the impact of hypoxia on the extravasation potential of breast cell lines
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21. Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma
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22. Alternative Splicing of <i>Cyr61</i> Is Regulated by Hypoxia and Significantly Changed in Breast Cancer
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23. Cancer cells depend on environmental lipids for proliferation when electron acceptors are limited
    Li, Zhaoqi, Ji, Brian W., Dixit, Purushottam D., Tchourine, Konstantine, Lien, Evan C., Hosios, Aaron M., Abbott, Keene L., Rutter, Justine C., Westermark, Anna M., Gorodetsky, Elizabeth F. et al. · 2022 · Nature Metabolism
24. In vitro hypoxia-conditioned colon cancer cell lines derived from HCT116 and HT29 exhibit altered apoptosis susceptibility and a more angiogenic profile in vivo
    Yao, K, Gietema, J A, Shida, S, Selvakumaran, M, Fonrose, X, Haas, N B, Testa, J, O'Dwyer, P J · 2005 · British Journal of Cancer
25. Hypoxia-inducible factor 1 alpha expression increases during colorectal carcinogenesis and tumor progression
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26. HIF-2α Enhances β-Catenin/TCF-Driven Transcription by Interacting with β-Catenin
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27. Chronic hypoxia promotes hypoxia-inducible factor-1α–dependent resistance to etoposide and vincristine in neuroblastoma cells
    Hussein, Deema, Estlin, Edward J., Dive, Caroline, Makin, Guy W.J. · 2006 · Molecular Cancer Therapeutics
28. Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways
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29. HIF-1α and HIF-2α Are Differentially Regulated <i>In vivo</i> in Neuroblastoma: High HIF-1α Correlates Negatively to Advanced Clinical Stage and Tumor Vascularization
    Noguera, Rosa, Fredlund, Erik, Piqueras, Marta, Pietras, Alexander, Beckman, Siv, Navarro, Samuel, Påhlman, Sven · 2009 · Clinical Cancer Research
30. HIF-1α and TAZ serve as reciprocal co-activators in human breast cancer cells
    Xiang, Lisha, Gilkes, Daniele M., Hu, Hongxia, Luo, Weibo, Bullen, John W., Liang, Houjie, Semenza, Gregg L. · 2015 · Oncotarget
31. Multiple drug resistance due to resistance to stem cells and stem cell treatment progress in cancer (Review)
    DI, CHONG, ZHAO, YAODONG · 2015 · Experimental and Therapeutic Medicine
32. Hypoxia-inducible factors promote breast cancer stem cell specification and maintenance in response to hypoxia or cytotoxic chemotherapy
    2019 · Advances in Cancer Research
33. Hypoxia-inducible factor orchestrates adenosine metabolism to promote liver cancer development
    Cheu, Jacinth Wing-Sum, Chiu, David Kung-Chun, Kwan, Kenneth Kin-Leung, Yang, Chunxue, Yuen, Vincent Wai-Hin, Goh, Chi Ching, Chui, Noreen Nog-Qin, Shen, Wei, Law, Cheuk-Ting, Li, Qidong et al. · 2023 · Science Advances
34. HIF1α regulated expression of XPA contributes to cisplatin resistance in lung cancer
    Liu, Yanbin, Bernauer, Amanda M., Yingling, Christin M., Belinsky, Steven A. · 2012 · Carcinogenesis
35. Hypoxia-inducible factors as key regulators of tumor inflammation
    Mamlouk, Soulafa, Wielockx, Ben · 2013 · International Journal of Cancer
36. A microfluidic-based PDAC organoid system reveals the impact of hypoxia in response to treatment
    Geyer, Marlene, Schreyer, Daniel, Gaul, Lisa-Marie, Pfeffer, Susanne, Pilarsky, Christian, Queiroz, Karla · 2023 · Cell Death Discovery
37. The Hypoxia-inducible Factor Renders Cancer Cells More Sensitive to Vitamin C-induced Toxicity
    Tian, Weihua, Wang, Yu, Xu, Yan, Guo, Xiangpeng, Wang, Bo, Sun, Li, Liu, Longqi, Cui, Fenggong, Zhuang, Qiang, Bao, Xichen et al. · 2014 · Journal of Biological Chemistry
38. Attenuating hypoxia driven malignant behavior in glioblastoma with a novel hypoxia-inducible factor 2 alpha inhibitor
    Renfrow, Jaclyn J., Soike, Michael H., West, James L., Ramkissoon, Shakti H., Metheny-Barlow, Linda, Mott, Ryan T., Kittel, Carol A., D’Agostino, Ralph B., Tatter, Stephen B., Laxton, Adrian W. et al. · 2020 · Scientific Reports
39. Cellular oxygen sensing, signalling and how to survive translational arrest in hypoxia
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40. Nanodelivery Systems for Nucleic Acid Therapeutics in Drug Resistant Tumors
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41. Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension
    Koens, Rei, Tabata, Yugo, Serrano, Jean C., Aratake, Satoshi, Yoshino, Daisuke, Kamm, Roger D., Funamoto, Kenichi · 2020 · APL Bioengineering
42. Severe OSA associated with higher risk of mortality in stage III and IV lung cancer
    Huang, Hung-Yu, Lin, Shih-Wei, Chuang, Li-Pang, Wang, Chih-Liang, Sun, Ming-Hui, Li, Hsueh-Yu, Chang, Chee-Jen, Chang, Shu-Chen, Yang, Cheng-Ta, Chen, Ning-Hung · 2020 · Journal of Clinical Sleep Medicine
43. Surviving hypoxia by modulation of mRNA translation rate
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44. Expression and Prognostic Significance of Hypoxia-Inducible Factor 1α (HIF-1α) in Malignant Pleural Mesothelioma (MPM)
    Klabatsa, A., Sheaff, M.T., Steele, J.P.C., Evans, M.T., Rudd, R.M., Fennell, D.A. · 2006 · Lung Cancer
45. The role of hypoxia-inducible factor-1 in three-dimensional tumor growth, apoptosis, and regulation by the insulin-signaling pathway
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46. Breast cancer hypoxia in relation to prognosis and benefit from radiotherapy after breast-conserving surgery in a large, randomised trial with long-term follow-up
    Tutzauer, Julia, Sjöström, Martin, Holmberg, Erik, Karlsson, Per, Killander, Fredrika, Leeb-Lundberg, L. M. Fredrik, Malmström, Per, Niméus, Emma, Fernö, Mårten, Jögi, Annika · 2022 · British Journal of Cancer
47. The Role of Solute Carrier Transporters in Efficient Anticancer Drug Delivery and Therapy
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48. A novel HIF-1α-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1α expression and epithelial-mesenchymal transition in cancer cells
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49. Hypoxia-Induced Alterations in Hyaluronan and Hyaluronidase
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50. IFNγR2 trafficking tunes IFNγ–STAT1 signaling in T lymphocytes
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51. Adaptation of Human CD4+ T Cells to Pathophysiological Hypoxia: A Transcriptome Analysis
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52. Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions
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53. Hypoxia-inducible factor 2α: a novel target in gliomas
    Renfrow, Jaclyn J, Soike, Michael H, Debinski, Waldemar, Ramkissoon, Shakti H, Mott, Ryan T, Frenkel, Mark B, Sarkaria, Jann N, Lesser, Glenn J, Strowd, Roy E · 2018 · Future Medicinal Chemistry
54. A Key Role for Cyclic AMP-Responsive Element Binding Protein in Hypoxia-Mediated Activation of the Angiogenesis Factor CCN1 (CYR61) in Tumor Cells
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55. Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide
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56. Clinicopathological and prognostic significance of hypoxia-inducible factor-1α in esophageal squamous cell carcinoma: a meta-analysis
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57. Cell Type-dependent HIF1 α-mediated Effects of Hypoxia on Proliferation, Migration and Metastatic Potential of Human Tumor Cells
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58. Myc-induced glutaminolysis bypasses HIF-driven glycolysis in hypoxic small cell lung carcinoma cells
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59. Clinicopathological and prognostic significance of HIF-1α and HIF-2α expression in small cell lung cancer
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61. OVER EXPRESSION OF HYPOXIA-INDUCIBLE FACTOR-1α IN RENAL AND BLADDER CANCER CELLS INCREASES TUMORIGENIC POTENCY
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62. Hypoxia-inducible factor: roles in development, physiology, and disease
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63. Recombinant Human Erythropoietin Alpha Improves the Efficacy of Radiotherapy of a Human Tumor Xenograft, Affecting Tumor Cells and Microvessels
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64. Interaction study of cancer cells and fibroblasts on a spatially confined oxygen gradient microfluidic chip to investigate the tumor microenvironment
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65. Metabolic profiling of hypoxia-inducible factor-1β-deficient and wild type Hepa-1 cells: Effects of hypoxia measured by 1H magnetic resonance spectroscopy
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66. HIF1α is not a target of 14q deletion in clear cell renal cancer
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67. Hypoxia‐inducible factor‐1α in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways
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